CN1250483A - 与质量标记连接的杂文探针 - Google Patents
与质量标记连接的杂文探针 Download PDFInfo
- Publication number
- CN1250483A CN1250483A CN98803287.2A CN98803287A CN1250483A CN 1250483 A CN1250483 A CN 1250483A CN 98803287 A CN98803287 A CN 98803287A CN 1250483 A CN1250483 A CN 1250483A
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- CN
- China
- Prior art keywords
- quality status
- status stamp
- base sequence
- mass
- probe
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
- C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
- C12Q1/6872—Methods for sequencing involving mass spectrometry
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
- C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
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- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Discharge Heating (AREA)
- Adhesives Or Adhesive Processes (AREA)
- Surgical Instruments (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Ultra Sonic Daignosis Equipment (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Description
Claims (50)
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9700746.2 | 1997-01-15 | ||
GBGB9700746.2A GB9700746D0 (en) | 1996-10-04 | 1997-01-15 | Hybridisation probes |
GB9718255.4 | 1997-08-28 | ||
GBGB9718255.4A GB9718255D0 (en) | 1996-10-04 | 1997-08-28 | Hybridisation probes |
GBGB9726953.4A GB9726953D0 (en) | 1997-12-19 | 1997-12-19 | Hybridisation probes |
GB9726953.4 | 1997-12-19 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1250483A true CN1250483A (zh) | 2000-04-12 |
CN100434531C CN100434531C (zh) | 2008-11-19 |
Family
ID=27268674
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CNB988032872A Expired - Fee Related CN100434531C (zh) | 1997-01-15 | 1998-01-15 | 与质量标记连接的杂交探针 |
Country Status (10)
Country | Link |
---|---|
EP (2) | EP1400599B1 (zh) |
JP (3) | JP3884087B2 (zh) |
CN (1) | CN100434531C (zh) |
AT (2) | ATE374836T1 (zh) |
AU (1) | AU725966B2 (zh) |
CA (2) | CA2277786A1 (zh) |
DE (2) | DE69836013T2 (zh) |
IL (1) | IL130885A (zh) |
NZ (1) | NZ336769A (zh) |
WO (1) | WO1998031830A1 (zh) |
Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101519698B (zh) * | 2008-03-10 | 2013-05-22 | 周国华 | 一种利用序列标签定量测定核酸的方法 |
CN106556661A (zh) * | 2015-09-30 | 2017-04-05 | 安捷伦科技有限公司 | 分析物衍生化和增强温和电离的方法 |
CN107614108A (zh) * | 2015-03-23 | 2018-01-19 | 因斯利克萨公司 | 使用集成阵列对核酸杂交热力学的多路分析 |
US11098345B2 (en) | 2006-06-05 | 2021-08-24 | California Institute Of Technology | Methods for detecting target analytes |
US11360029B2 (en) | 2019-03-14 | 2022-06-14 | Insilixa, Inc. | Methods and systems for time-gated fluorescent-based detection |
US11447816B2 (en) | 2006-07-28 | 2022-09-20 | California Institute Of Technology | Multiplex Q-PCR arrays |
US11485997B2 (en) | 2016-03-07 | 2022-11-01 | Insilixa, Inc. | Nucleic acid sequence identification using solid-phase cyclic single base extension |
US11525156B2 (en) | 2006-07-28 | 2022-12-13 | California Institute Of Technology | Multiplex Q-PCR arrays |
US11560588B2 (en) | 2006-08-24 | 2023-01-24 | California Institute Of Technology | Multiplex Q-PCR arrays |
Families Citing this family (82)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9707980D0 (en) * | 1997-04-21 | 1997-06-11 | Brax Genomics Ltd | Characterising DNA |
CN1270598A (zh) * | 1997-07-22 | 2000-10-18 | 拉普吉恩公司 | 用于质谱分析核酸的方法和组合物 |
GB9718921D0 (en) | 1997-09-05 | 1997-11-12 | Brax Genomics Ltd | Catalytically generated mass labels |
AU746443B2 (en) * | 1997-09-15 | 2002-05-02 | Xzillion Gmbh & Co. Kg | Characterising nucleic acid by mass spectrometry |
DK1036202T3 (da) * | 1997-12-05 | 2002-08-12 | Max Planck Gesellschaft | Fremgangsmåde til identifikation af nucleinsyrer ved matriksassisteret laserdesorptions/ionisationsmassespektrometri |
GB9815164D0 (en) * | 1998-07-13 | 1998-09-09 | Brax Genomics Ltd | Compounds for mass spectrometry |
GB9823646D0 (en) | 1997-12-19 | 1998-12-23 | Brax Genomics Ltd | Compounds for mass spectrometry |
GB9815166D0 (en) * | 1998-07-13 | 1998-09-09 | Brax Genomics Ltd | Compounds for mass spectrometry |
GB9815163D0 (en) * | 1998-07-13 | 1998-09-09 | Brax Genomics Ltd | Compounds |
CA2332862A1 (en) | 1998-05-15 | 1999-11-25 | Isis Innovation Ltd. | Libraries of oligomers labelled with different tags |
US7399844B2 (en) | 1998-07-09 | 2008-07-15 | Agilent Technologies, Inc. | Method and reagents for analyzing the nucleotide sequence of nucleic acids |
US6270976B1 (en) | 1998-09-15 | 2001-08-07 | Brax Group Limited | Characterizing nucleic acid by mass spectrometry |
JP3668075B2 (ja) * | 1999-10-12 | 2005-07-06 | 光夫 板倉 | 遺伝物質シーケンス決定用懸濁系、その懸濁系を用いた遺伝物質シーケンス決定方法およびその懸濁系を用いたSNPs高速スコアリング方法 |
US6509157B1 (en) * | 1999-11-05 | 2003-01-21 | Roche Molecular Systems, Inc | 3 blocked nucleic acid amplification primers |
DE19963536C2 (de) * | 1999-12-20 | 2003-04-10 | Epigenomics Ag | Verfahren zur Analyse von Nukleinsäuresequenzen |
JP2001204463A (ja) * | 2000-01-27 | 2001-07-31 | Toyo Kohan Co Ltd | ヌクレオチド固定用担体 |
GB0006141D0 (en) | 2000-03-14 | 2000-05-03 | Brax Group Ltd | Mass labels |
AU5951201A (en) | 2000-05-04 | 2001-11-12 | Univ Yale | High density protein arrays for screening of protein activity |
CA2419159A1 (en) | 2000-08-11 | 2002-02-21 | Agilix Corporation | Ultra-sensitive detection systems |
ATE552348T1 (de) | 2000-10-19 | 2012-04-15 | Target Discovery Inc | Massendefektetikettierung zur bestimmung von oligomersequenzen |
JPWO2002050307A1 (ja) * | 2000-12-12 | 2004-04-22 | 中外製薬株式会社 | 質量分析を利用してdnaの多型を検出する方法 |
US20040121313A1 (en) | 2002-12-06 | 2004-06-24 | Ecker David J. | Methods for rapid detection and identification of bioagents in organs for transplantation |
US7666588B2 (en) | 2001-03-02 | 2010-02-23 | Ibis Biosciences, Inc. | Methods for rapid forensic analysis of mitochondrial DNA and characterization of mitochondrial DNA heteroplasmy |
US7226739B2 (en) | 2001-03-02 | 2007-06-05 | Isis Pharmaceuticals, Inc | Methods for rapid detection and identification of bioagents in epidemiological and forensic investigations |
US20030027135A1 (en) | 2001-03-02 | 2003-02-06 | Ecker David J. | Method for rapid detection and identification of bioagents |
US7217510B2 (en) | 2001-06-26 | 2007-05-15 | Isis Pharmaceuticals, Inc. | Methods for providing bacterial bioagent characterizing information |
JP4290003B2 (ja) | 2001-09-14 | 2009-07-01 | エレクトロフォレティクス リミテッド | 質量標識体 |
EP1490693A1 (en) | 2002-04-04 | 2004-12-29 | Xzillion GmbH & CO.KG | Method for characterising analytes |
JP2004037128A (ja) * | 2002-06-28 | 2004-02-05 | Canon Inc | マトリクス援助レーザー脱着/イオン化飛行時間型質量分析法による基板上の物質の解析方法 |
EP2722869A1 (en) | 2002-10-29 | 2014-04-23 | Target Discovery, Inc. | Method for increasing ionization efficiency in mass spectroscopy |
JP2006516193A (ja) | 2002-12-06 | 2006-06-29 | アイシス・ファーマシューティカルス・インコーポレーテッド | ヒトおよび動物における病原体の迅速な同定方法 |
US7195751B2 (en) | 2003-01-30 | 2007-03-27 | Applera Corporation | Compositions and kits pertaining to analyte determination |
US7964343B2 (en) | 2003-05-13 | 2011-06-21 | Ibis Biosciences, Inc. | Method for rapid purification of nucleic acids for subsequent analysis by mass spectrometry by solution capture |
US8158354B2 (en) | 2003-05-13 | 2012-04-17 | Ibis Biosciences, Inc. | Methods for rapid purification of nucleic acids for subsequent analysis by mass spectrometry by solution capture |
US8546082B2 (en) | 2003-09-11 | 2013-10-01 | Ibis Biosciences, Inc. | Methods for identification of sepsis-causing bacteria |
US20120122099A1 (en) | 2003-09-11 | 2012-05-17 | Rangarajan Sampath | Compositions for use in identification of bacteria |
US8097416B2 (en) | 2003-09-11 | 2012-01-17 | Ibis Biosciences, Inc. | Methods for identification of sepsis-causing bacteria |
JP2005140755A (ja) * | 2003-11-10 | 2005-06-02 | Japan Science & Technology Agency | 質量分析用プローブ及びそれを用いた質量分析方法 |
US8163895B2 (en) | 2003-12-05 | 2012-04-24 | Ibis Biosciences, Inc. | Compositions for use in identification of orthopoxviruses |
US7355045B2 (en) | 2004-01-05 | 2008-04-08 | Applera Corporation | Isotopically enriched N-substituted piperazine acetic acids and methods for the preparation thereof |
US7307169B2 (en) | 2004-01-05 | 2007-12-11 | Applera Corporation | Isotopically enriched N-substituted piperazines and methods for the preparation thereof |
US20050148087A1 (en) | 2004-01-05 | 2005-07-07 | Applera Corporation | Isobarically labeled analytes and fragment ions derived therefrom |
US7666592B2 (en) | 2004-02-18 | 2010-02-23 | Ibis Biosciences, Inc. | Methods for concurrent identification and quantification of an unknown bioagent |
WO2005085869A2 (en) | 2004-03-01 | 2005-09-15 | Applera Corporation | Determination of analyte characteristics based upon binding properties |
ES2641832T3 (es) | 2004-05-24 | 2017-11-14 | Ibis Biosciences, Inc. | Espectrometría de masas con filtración de iones selectiva por establecimiento de umbrales digitales |
US20050266411A1 (en) | 2004-05-25 | 2005-12-01 | Hofstadler Steven A | Methods for rapid forensic analysis of mitochondrial DNA |
US20070048752A1 (en) | 2004-07-12 | 2007-03-01 | Applera Corporation | Mass tags for quantitative analyses |
US7811753B2 (en) | 2004-07-14 | 2010-10-12 | Ibis Biosciences, Inc. | Methods for repairing degraded DNA |
US7943294B2 (en) | 2004-07-30 | 2011-05-17 | Hologic, Inc. | Methods for detecting oncofetal fibronectin |
US20060183238A1 (en) | 2005-02-09 | 2006-08-17 | Applera Corporation | Amine-containing compound analysis methods |
CA2600184A1 (en) | 2005-03-03 | 2006-09-08 | Isis Pharmaceuticals, Inc. | Compositions for use in identification of adventitious viruses |
US8084207B2 (en) | 2005-03-03 | 2011-12-27 | Ibis Bioscience, Inc. | Compositions for use in identification of papillomavirus |
CA2616281C (en) | 2005-07-21 | 2014-04-22 | Isis Pharmaceuticals, Inc. | Methods for rapid identification and quantitation of mitochondrial dna variants |
GB0515323D0 (en) | 2005-07-26 | 2005-08-31 | Electrophoretics Ltd | Mass labels |
GB0518585D0 (en) * | 2005-09-12 | 2005-10-19 | Electrophoretics Ltd | Mass labels |
US8975404B2 (en) | 2006-01-24 | 2015-03-10 | Dh Technologies Development Pte. Ltd. | Labeling reagents for analyte determination and methods and compounds used in making the same |
EP2010679A2 (en) | 2006-04-06 | 2009-01-07 | Ibis Biosciences, Inc. | Compositions for the use in identification of fungi |
JP5413836B2 (ja) | 2006-05-26 | 2014-02-12 | ディーエイチ テクノロジーズ デベロップメント プライベート リミテッド | ヒドロキシル化化合物のためのタグ付け試薬およびその方法 |
US7906341B2 (en) | 2006-06-30 | 2011-03-15 | Dh Technologies Development Pte, Ltd. | Methods, mixtures, kits and compositions pertaining to analyte determination |
US8362242B2 (en) | 2006-06-30 | 2013-01-29 | Dh Technologies Development Pte. Ltd. | Analyte determination utilizing mass tagging reagents comprising a non-encoded detectable label |
CA2663029C (en) | 2006-09-14 | 2016-07-19 | Ibis Biosciences, Inc. | Targeted whole genome amplification method for identification of pathogens |
WO2008104002A2 (en) | 2007-02-23 | 2008-08-28 | Ibis Biosciences, Inc. | Methods for rapid forensic dna analysis |
GB0704764D0 (en) | 2007-03-12 | 2007-04-18 | Electrophoretics Ltd | Isobarically labelled reagents and methods of their use |
WO2008151023A2 (en) | 2007-06-01 | 2008-12-11 | Ibis Biosciences, Inc. | Methods and compositions for multiple displacement amplification of nucleic acids |
EP2347254A2 (en) | 2008-09-16 | 2011-07-27 | Ibis Biosciences, Inc. | Sample processing units, systems, and related methods |
US8534447B2 (en) | 2008-09-16 | 2013-09-17 | Ibis Biosciences, Inc. | Microplate handling systems and related computer program products and methods |
EP2349549B1 (en) | 2008-09-16 | 2012-07-18 | Ibis Biosciences, Inc. | Mixing cartridges, mixing stations, and related kits, and system |
US8158936B2 (en) | 2009-02-12 | 2012-04-17 | Ibis Biosciences, Inc. | Ionization probe assemblies |
WO2010104798A1 (en) | 2009-03-08 | 2010-09-16 | Ibis Biosciences, Inc. | Bioagent detection methods |
EP2406634A4 (en) | 2009-03-10 | 2013-06-19 | Univ Maryland | ISOBARE DEUTERIUM REACTIVE MARKERS USED FOR QUANTITATIVE ANALYZES |
US9393564B2 (en) | 2009-03-30 | 2016-07-19 | Ibis Biosciences, Inc. | Bioagent detection systems, devices, and methods |
WO2011008971A1 (en) | 2009-07-17 | 2011-01-20 | Ibis Biosciences, Inc. | Lift and mount apparatus |
WO2011008972A1 (en) | 2009-07-17 | 2011-01-20 | Ibis Biosciences, Inc. | Systems for bioagent identification |
WO2011014811A1 (en) | 2009-07-31 | 2011-02-03 | Ibis Biosciences, Inc. | Capture primers and capture sequence linked solid supports for molecular diagnostic tests |
EP2462244B1 (en) | 2009-08-06 | 2016-07-20 | Ibis Biosciences, Inc. | Non-mass determined base compositions for nucleic acid detection |
ES2628739T3 (es) | 2009-10-15 | 2017-08-03 | Ibis Biosciences, Inc. | Amplificación por desplazamiento múltiple |
US9758840B2 (en) | 2010-03-14 | 2017-09-12 | Ibis Biosciences, Inc. | Parasite detection via endosymbiont detection |
WO2012003478A2 (en) | 2010-07-02 | 2012-01-05 | Ventana Medical Systems, Inc. | Detecting targets using mass tags and mass spectrometry |
US8492163B2 (en) | 2011-01-31 | 2013-07-23 | Dh Technologies Development Pte. Ltd. | Methods, mixtures, kits and compositions pertaining to analyte determination |
EP3400444A4 (en) * | 2016-01-04 | 2019-10-16 | QuantuMDx Group Limited | DESIGN, SYNTHESIS AND USE OF SYNTHETIC NUCLEOTIDES COMPRISING SPECIFIC CHARGE LABELS |
EP4240872A1 (en) * | 2020-11-06 | 2023-09-13 | Waters Technologies Corporation | Methods and compositions useful for nucleic acid analysis |
CN116496335B (zh) * | 2023-03-21 | 2024-03-08 | 中国药科大学 | 一种修饰核苷酸及其应用 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1994016101A2 (en) * | 1993-01-07 | 1994-07-21 | Koester Hubert | Dna sequencing by mass spectrometry |
GB9315847D0 (en) * | 1993-07-30 | 1993-09-15 | Isis Innovation | Tag reagent and assay method |
US5707807A (en) * | 1995-03-28 | 1998-01-13 | Research Development Corporation Of Japan | Molecular indexing for expressed gene analysis |
CA2218188A1 (en) * | 1995-04-11 | 1996-10-17 | Trustees Of Boston University | Solid phase sequencing of biopolymers |
NZ331043A (en) * | 1996-01-23 | 1999-01-28 | Rapigene Inc | Methods and compositions for analyzing nucleic acid molecules utilizing sizing techniques |
GB9618544D0 (en) * | 1996-09-05 | 1996-10-16 | Brax Genomics Ltd | Characterising DNA |
-
1998
- 1998-01-15 NZ NZ336769A patent/NZ336769A/xx unknown
- 1998-01-15 EP EP03076965A patent/EP1400599B1/en not_active Expired - Lifetime
- 1998-01-15 CA CA002277786A patent/CA2277786A1/en active Pending
- 1998-01-15 DE DE69836013T patent/DE69836013T2/de not_active Expired - Lifetime
- 1998-01-15 AU AU55700/98A patent/AU725966B2/en not_active Ceased
- 1998-01-15 JP JP53394298A patent/JP3884087B2/ja not_active Expired - Fee Related
- 1998-01-15 CN CNB988032872A patent/CN100434531C/zh not_active Expired - Fee Related
- 1998-01-15 EP EP98900611A patent/EP0979305B1/en not_active Expired - Lifetime
- 1998-01-15 IL IL13088598A patent/IL130885A/xx not_active IP Right Cessation
- 1998-01-15 DE DE69838519T patent/DE69838519T2/de not_active Expired - Lifetime
- 1998-01-15 WO PCT/GB1998/000127 patent/WO1998031830A1/en active IP Right Grant
- 1998-01-15 CA CA002441655A patent/CA2441655A1/en not_active Abandoned
- 1998-01-15 AT AT03076965T patent/ATE374836T1/de not_active IP Right Cessation
- 1998-01-15 AT AT98900611T patent/ATE340869T1/de not_active IP Right Cessation
-
2004
- 2004-02-13 JP JP2004036206A patent/JP2004357697A/ja not_active Withdrawn
-
2006
- 2006-04-19 JP JP2006115777A patent/JP2006208400A/ja active Pending
Cited By (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11098345B2 (en) | 2006-06-05 | 2021-08-24 | California Institute Of Technology | Methods for detecting target analytes |
US11447816B2 (en) | 2006-07-28 | 2022-09-20 | California Institute Of Technology | Multiplex Q-PCR arrays |
US11525156B2 (en) | 2006-07-28 | 2022-12-13 | California Institute Of Technology | Multiplex Q-PCR arrays |
US11560588B2 (en) | 2006-08-24 | 2023-01-24 | California Institute Of Technology | Multiplex Q-PCR arrays |
CN101519698B (zh) * | 2008-03-10 | 2013-05-22 | 周国华 | 一种利用序列标签定量测定核酸的方法 |
CN107614108A (zh) * | 2015-03-23 | 2018-01-19 | 因斯利克萨公司 | 使用集成阵列对核酸杂交热力学的多路分析 |
CN107614108B (zh) * | 2015-03-23 | 2020-10-23 | 因斯利克萨公司 | 使用集成阵列对核酸杂交热力学的多路分析 |
CN106556661A (zh) * | 2015-09-30 | 2017-04-05 | 安捷伦科技有限公司 | 分析物衍生化和增强温和电离的方法 |
US11485997B2 (en) | 2016-03-07 | 2022-11-01 | Insilixa, Inc. | Nucleic acid sequence identification using solid-phase cyclic single base extension |
US11360029B2 (en) | 2019-03-14 | 2022-06-14 | Insilixa, Inc. | Methods and systems for time-gated fluorescent-based detection |
Also Published As
Publication number | Publication date |
---|---|
AU5570098A (en) | 1998-08-07 |
EP0979305B1 (en) | 2006-09-27 |
CN100434531C (zh) | 2008-11-19 |
EP1400599B1 (en) | 2007-10-03 |
JP2001508307A (ja) | 2001-06-26 |
CA2441655A1 (en) | 1998-07-23 |
DE69838519D1 (de) | 2007-11-15 |
ATE340869T1 (de) | 2006-10-15 |
WO1998031830A1 (en) | 1998-07-23 |
JP2006208400A (ja) | 2006-08-10 |
EP1400599A1 (en) | 2004-03-24 |
DE69838519T2 (de) | 2008-07-03 |
DE69836013D1 (de) | 2006-11-09 |
ATE374836T1 (de) | 2007-10-15 |
CA2277786A1 (en) | 1998-07-23 |
IL130885A (en) | 2005-05-17 |
EP0979305A1 (en) | 2000-02-16 |
JP3884087B2 (ja) | 2007-02-21 |
JP2004357697A (ja) | 2004-12-24 |
AU725966B2 (en) | 2000-10-26 |
DE69836013T2 (de) | 2007-05-24 |
IL130885A0 (en) | 2001-01-28 |
NZ336769A (en) | 2001-01-26 |
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