The Cholinesterase Test checks enzyme activity for nerve health and toxin exposure. It's crucial in industries to ensure worker safety and overall well-being. Learn how it safeguards against potential health risks.
Here are the basic details of the Cholinesterase Test.
Also Known As | Cholinesterase Activity Test |
Type | Blood Test |
Purpose | Assess nerve health & toxin exposure |
Sample Type | Serum |
Preparation | No |
Fasting | No required |
Gender | Unisex |
Age Group | All |
Normal Value | 8-18 (U/mL) |
Reporting Time | A few days |
Cost | 450-900 INR* |
*Price range may vary as per location, lab type, and procedure of lab test.
A Cholinesterase Test measures the activity of cholinesterase enzymes to evaluate nerve health and detect exposure to toxins, especially in occupational settings.
The purpose of the Cholinesterase Test is to:
Here is the basic preparation for the Cholinesterase Test.
Here is the basic Cholinesterase Test Procedure.
Here is the normal range of the Cholinesterase Test.
Measurement | Normal Range |
---|---|
Pseudocholinesterase | 8-18 U/mL or 8-18 kU/L |
Here is the Interpretation of the Cholinesterase Test.
Result | Interpretation |
---|---|
< 35% of normal | Suggestive of severe poisoning |
35-50% of normal | Indicative of mild to moderate poisoning |
50-100% of normal | Within the expected range (normal or no poisoning) |
Above 100% of normal | Higher than normal, but not related to poisoning |
Cholinesterase Test assesses enzyme activity, with a normal range of 8-18 U/mL or 8-18 kU/L; a drop of >35% suggests severe poisoning.
Here are some possible causes of high Cholinesterase levels:
Possible Causes | Description |
---|---|
Liver Disease | Impaired metabolism due to liver dysfunction |
Pregnancy | Normal physiological increase during pregnancy |
Some Medications | Certain drugs can temporarily elevate levels |
High Cholinesterase levels can result from liver disease, pregnancy, or specific medications.
Here are some possible causes of low Cholinesterase levels:
Possible Causes | Description |
---|---|
Organophosphate Poisoning | Exposure to toxic chemicals like pesticides |
Succinylcholine Sensitivity | Inherited enzyme deficiency affecting drug metabolism |
Chronic Liver Disease | Liver dysfunction leading to enzyme reduction |
Malnutrition | Inadequate nutrition can lower enzyme levels |
Renal Disease | Kidney problems may impact enzyme activity |
Cholinesterase Test assesses enzyme levels; low levels may signal poisoning or medical conditions like liver disease.
Here are the specimen requirements for the Cholinesterase Test.
Specimen |
Serum |
|
Volume |
0.5 mL |
|
Container |
Red-top tube or gel-barrier tube |
|
Collection |
Separate serum from cells immediately after clotting (30 minutes) and place in transport tube. Mark transport tube “serum”. |
|
Storage |
Room temperature |
|
Sample Stability |
Temperature |
Period |
Room temperature |
14 days |
|
Refrigerated |
14 days |
|
Frozen |
14 days |
|
Freeze/thaw cycles |
Stable x3 |
|
Causes for Rejection |
Whole blood specimen (a 20% to 25% increase can occur over a 24-hour period if serum is left on the clot); hemolysis |
Cholinesterase Test is generally safe.
Here is the basic limitation of Cholinesterase Test.
Here are some of the risk factors of the Cholinesterase Test.
Here are the Doctor's recommendations or consult a specialist after the Cholinesterase Test.
Cholinesterase Result | Doctor to Consult | Reason |
---|---|---|
High | Primary Care Physician or Specialist | Determine underlying cause. |
Normal | No specific visit required | - |
Low | Primary Care Physician or Specialist | Assess potential toxin exposure. |
Here are the estimated Cholinesterase Test Prices in India with different top cities:
City |
Price Range (INR)* |
400-900 |
|
450-900 |
|
400-900 |
|
450-900 |
|
400-900 |
|
450-900 |
|
400-900 |
|
450-900 |
|
450-900 |
|
400-900 |
|
450-900 |
|
400-900 |
|
450-900 |
|
400-900 |
*Prices are approximate and vary depending on a specific laboratory or healthcare facility.
Summary
Overall, The Cholinesterase Test evaluates nerve health and toxin exposure, aiding in the detection of pesticide poisoning and anesthesia sensitivity. Also check Drlogy Test for detailed information about all medical tests for patients, doctors, scholers and medical students.
Reference
The cost of a Cholinesterase Test typically ranges from INR 700 to INR 1000 in India. However, it's important to note that the exact cost may vary depending on the location of the healthcare facility, any additional services or consultations included, and whether you have health insurance coverage. It's advisable to check with the specific laboratory or healthcare provider for the most accurate pricing information for the test.
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