To find out incidence & mortality due to Neonatal Tetanus and to study its causes among all the admissions in Neonatal Intensive Care Unit [NICU] of tertiary health care center of Shri Bhausaheb Hire Government Medical College, [SBHGMC] Dhule. OBJECTIVES: 1] To find out incidence of Neonatal Tetanus in all neonatal admissions. 2] To find out mortality rate among all Neonatal Tetanus cases. 3] To take detailed history to find out causes of Neonatal Tetanus. MATERIALS & METHODS: Prospective interventional study was conducted in all neonates admitted in NICU of SBHGMC, a tertiary care center during 1st January 2013 to 31st December 2013. Cases of Neonatal Tetanus were diagnosed by taking detailed history & examination. All cases were treated using standard protocol. Incidence & mortality were calculated and causes noted from data obtained. RESULTS: Incidence of Neonatal Tetanus was found to be 2% while mortality was very high i.e. 87.50%. Cause of Neonatal Tetanus in this study were found to be home deliveries, deliveries by untrained person, application of ash on umbilical stump & improper immunization of mother during pregnancy. CONCLUSION: Neonatal Tetanus is completely preventable disease. Combination of high levels of tetanus toxoid Vaccination coverage during antenatal period, safe birth practices and care in post-partum period will definitely help to decrease neonatal mortality due to Neonatal Tetanus. KEYWORDS: Neonatal Tetanus, clostridium Tetani.