FRONTONASAL DYSPLASIA Syn.:- Median Cleft Face Syndrome AETIOLOGY :•The basic defect is unknown but thought to result from failure of flow of ectomesenchyme allowing brain vesicle to fill space normally occupied by the nasal capsule CLINICAL FEATURES:•Facial alteration graded from mild to severe •Anterior encephalocoele in some •Occular hypertelorism •Microopthalmia •Nose often flattened with widely spaced nostrils •Cleft lip •Mental Retardation
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