Skip to main content
Log in

Fetal Oropharyngeal Teratoma: A Case Report

  • Case Reports
  • Published:
Journal of Fetal Medicine

Abstract

Oropharyngeal teratomas are extremely rare fetal tumors and originate from pluripotent stem cells. The tumor typically arises from the palato-pharyngeal region around the basishenoid. These tumors are heterogenous in nature. The reported case was diagnosed at 20 weeks gestation. Ultrasound revealed a heterogenous, lobulated facial mass protruded from the oral cavity without any hypervascularity or intracranial extension. There was no evidence of polyhydromnios. After counseling, the parents opted for termination of pregnancy. Histopathological examination from the exophytic mass was consistent with immature teratoma containing components of all three germ cell layers. Genetic testing and fetal autopsy could not be arranged due to financial and infrastructural constraints.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5

References

  1. Morof D, Levine D, Grable I, et al. Oropharyngeal teratoma: prenatal diagnosis and assessment using sonography, MRI, and CT with management by ex utero intrapartum treatment procedure. AJR. 2004;183:493–6.

    Article  Google Scholar 

  2. Sarioglu N, Wegner RD, Gasiorek-Wiens A, et al. Epignathus: always a simple teratoma? Report of an exceptional case with two additional fetiforme bodies. Ultrasound Obstet Gynecol. 2003;21:397–403. https://doi.org/10.1002/uog.92.

    Article  CAS  PubMed  Google Scholar 

  3. Smith NM, Chambers SE, Billson VR, Lang I, West CP, Bell JE. Oral teratoma (epignathus) with intracranial extension: a report of two cases. Prenat Diagn. 1993;13:945–52.

    Article  CAS  Google Scholar 

  4. Prakash A, Parelkar SV, Oak SN, Gupta RK, Sanghvi BV. Giant epignathus with midline mandibular cleft: insights in embryology and management. Ann Maxillofac Surg. 2012;2:56–9. https://doi.org/10.4103/2231-0746.95322.

    Article  PubMed  PubMed Central  Google Scholar 

  5. Smart PJ, Schwarz C, Kelsey A. Ultrasonographic and biochemical abnormalities associated with prenatal diagnosis of epignathus. Prenat Diagn. 1990;10:327–32.

    Article  CAS  Google Scholar 

  6. Calda P, Novotna M, Cutka D, Bet’ak M, Halik L, Goldova B, et al. A case of an epignathus with intracranial extension appearing as a persistently open mouth at 16 weeks and subsequently diagnosed at 20 weeks of gestation. J Clin Ultrasound. 2011;39:164–8. https://doi.org/10.1002/jcu.20762.

    Article  PubMed  Google Scholar 

  7. Schwartz S, Raffel LJ, Sun CC, Waters E. An unusual mosaic karyotype detected through prenatal diagnosis with duplication of 1q and 19p and associated teratoma development. Teratology. 1992;46(4):399–404.

    Article  CAS  Google Scholar 

  8. Ashley DJ. Origin of teratomas. Cancer. 1973;32(2):390–4.

    Article  CAS  Google Scholar 

  9. Manchali MM, Sharabu C, Latha M, Kumar L. A rare case of oropharyngeal teratoma diagnosed antenatally with MRI. J Clin Imaging Sci. 2014;4:15.

    Article  Google Scholar 

  10. Smith NM, Chambers SE, Billson VR, West CP, Bell JE. Oral teratoma (epignathus) with intracranial extension: a report of two cases. Prenat Diagn. 1993;13:945–52.

    Article  CAS  Google Scholar 

  11. Vandenhaute B, Leteurtre E, Lecomte-houcke M, Pelerin P, Nuyts JP, Cuisset JM, Soto-ares G. Epignathus teratoma: report of three cases with a review of the literature. Cleft Palate-Craniofac J. 2000;37:83–91.

    Article  CAS  Google Scholar 

  12. Lang E, Loughrey J, Hunter K, Rowley H. Ex utero intrapartum treatment (EXIT) procedure and simultaneous excision of oral teratoma. Ir Med J. 2007;100(10):632–3.

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Kanchan Mukherjee.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Mukherjee, A., Kundu, S. & Mukherjee, K. Fetal Oropharyngeal Teratoma: A Case Report. J. Fetal Med. 8, 237–241 (2021). https://doi.org/10.1007/s40556-021-00319-1

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s40556-021-00319-1

Keywords

Navigation