Abstract
Oropharyngeal teratomas are extremely rare fetal tumors and originate from pluripotent stem cells. The tumor typically arises from the palato-pharyngeal region around the basishenoid. These tumors are heterogenous in nature. The reported case was diagnosed at 20 weeks gestation. Ultrasound revealed a heterogenous, lobulated facial mass protruded from the oral cavity without any hypervascularity or intracranial extension. There was no evidence of polyhydromnios. After counseling, the parents opted for termination of pregnancy. Histopathological examination from the exophytic mass was consistent with immature teratoma containing components of all three germ cell layers. Genetic testing and fetal autopsy could not be arranged due to financial and infrastructural constraints.
References
Morof D, Levine D, Grable I, et al. Oropharyngeal teratoma: prenatal diagnosis and assessment using sonography, MRI, and CT with management by ex utero intrapartum treatment procedure. AJR. 2004;183:493–6.
Sarioglu N, Wegner RD, Gasiorek-Wiens A, et al. Epignathus: always a simple teratoma? Report of an exceptional case with two additional fetiforme bodies. Ultrasound Obstet Gynecol. 2003;21:397–403. https://doi.org/10.1002/uog.92.
Smith NM, Chambers SE, Billson VR, Lang I, West CP, Bell JE. Oral teratoma (epignathus) with intracranial extension: a report of two cases. Prenat Diagn. 1993;13:945–52.
Prakash A, Parelkar SV, Oak SN, Gupta RK, Sanghvi BV. Giant epignathus with midline mandibular cleft: insights in embryology and management. Ann Maxillofac Surg. 2012;2:56–9. https://doi.org/10.4103/2231-0746.95322.
Smart PJ, Schwarz C, Kelsey A. Ultrasonographic and biochemical abnormalities associated with prenatal diagnosis of epignathus. Prenat Diagn. 1990;10:327–32.
Calda P, Novotna M, Cutka D, Bet’ak M, Halik L, Goldova B, et al. A case of an epignathus with intracranial extension appearing as a persistently open mouth at 16 weeks and subsequently diagnosed at 20 weeks of gestation. J Clin Ultrasound. 2011;39:164–8. https://doi.org/10.1002/jcu.20762.
Schwartz S, Raffel LJ, Sun CC, Waters E. An unusual mosaic karyotype detected through prenatal diagnosis with duplication of 1q and 19p and associated teratoma development. Teratology. 1992;46(4):399–404.
Ashley DJ. Origin of teratomas. Cancer. 1973;32(2):390–4.
Manchali MM, Sharabu C, Latha M, Kumar L. A rare case of oropharyngeal teratoma diagnosed antenatally with MRI. J Clin Imaging Sci. 2014;4:15.
Smith NM, Chambers SE, Billson VR, West CP, Bell JE. Oral teratoma (epignathus) with intracranial extension: a report of two cases. Prenat Diagn. 1993;13:945–52.
Vandenhaute B, Leteurtre E, Lecomte-houcke M, Pelerin P, Nuyts JP, Cuisset JM, Soto-ares G. Epignathus teratoma: report of three cases with a review of the literature. Cleft Palate-Craniofac J. 2000;37:83–91.
Lang E, Loughrey J, Hunter K, Rowley H. Ex utero intrapartum treatment (EXIT) procedure and simultaneous excision of oral teratoma. Ir Med J. 2007;100(10):632–3.
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Mukherjee, A., Kundu, S. & Mukherjee, K. Fetal Oropharyngeal Teratoma: A Case Report. J. Fetal Med. 8, 237–241 (2021). https://doi.org/10.1007/s40556-021-00319-1
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DOI: https://doi.org/10.1007/s40556-021-00319-1