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Digestive System

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The Pathophysiologic Basis of Nuclear Medicine

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Abstract

The digestive system consists of the gastrointestinal tract, hepatobiliary system, pancreas, and salivary glands. Nuclear medicine is concerned with the evaluation of normal and abnormal functions of the gastrointestinal tract and hepatobiliary system. To date, the role of nuclear medicine in pancreatic disorders is limited to evaluation of its tumors which is dealt with elsewhere in the book. This chapter deals with gastrointestinal tract, salivary glands, and the hepatobiliary system. It discusses pathophysiologic changes of the most relevant diseases and diagnostic imaging in a correlative approach.

The primary purpose of scintigraphic liver imaging includes tissue-specific characterization of hepatic lesions, evaluation of functional liver mass, and evaluation of hepatobiliary function. Advances in instrumentation, e.g., the use of single-photon emission computed tomography/X-ray computed tomography (SPECT/CT), use of pharmacological interventions in conjunction with cholescintigraphy, and development of new radiopharmaceuticals have significantly improved the efficacy of scintigraphic imaging with expanded clinical applications. Scintigraphy has proven extremely useful in the diagnosis of acute cholecystitis, chronic gall bladder disease, biliary leaks, biliary obstruction, and biliary atresia.

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    Abdelhamid H. Elgazzar & Saud A. Alenezi

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Elgazzar, A.H., Alenezi, S.A. (2022). Digestive System. In: Elgazzar, A.H. (eds) The Pathophysiologic Basis of Nuclear Medicine. Springer, Cham. https://doi.org/10.1007/978-3-030-96252-4_10

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