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4 Functional and Nonfunctional Pituitary Adenomas

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Endoscopic and Keyhole Cranial Base Surgery

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Abstract

Pituitary adenomas are slow-growing, benign tumors that arise from the cells of the pituitary gland. They can be nonfunctional or functional depending on whether they secrete hormones. For non-prolactin-secreting adenomas that are symptomatic through mass effect on local structures or hormonal hypersecretion, or nonfunctional adenomas large enough to warrant elective treatment, surgery is typically recommended. The endoscopic endonasal approach provides safe and thorough exposure of the sella and any tumors within it. Here, we review the process of evaluating patients with pituitary tumors, including the necessary laboratory and radiographic tests for these patients, and the technical aspects of endoscopic endonasal surgery for pituitary tumors, including preoperative considerations, operative technique and nuances, and postoperative complications. In the hands of an experienced neurosurgeon, the endoscopic endonasal technique is quite successful at resecting these common tumors and helping patients improve or maintain their quality of life.

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Authors and Affiliations

  1. Department of Neurological Surgery, University of California San Francisco, CA, USA

    Ankush Chandra & Manish K. Aghi

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  1. Ankush Chandra
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  2. Manish K. Aghi
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Correspondence to Manish K. Aghi .

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Editors and Affiliations

  1. Cranial Base and Pituitary Surgery Department of Neurosurgery, Thomas Jefferson University, Philadelphia, PA, USA

    James J. Evans

  2. Pituitary and Cranial Base Surgery, Department of Neurosurgery, Albany Medical Center, Albany, NY, USA

    Tyler J. Kenning

  3. Cranial Base and Pituitary Surgery Department of Neurosurgery, Thomas Jefferson University, Philadelphia, PA, USA

    Christopher Farrell

  4. Skull Base, Pituitary and Cerebrovascular Surgery Department of Neurosurgery, Cleveland Clinic, Cleveland, OH, USA

    Varun R. Kshettry

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Chandra, A., Aghi, M.K. (2019). 4 Functional and Nonfunctional Pituitary Adenomas. In: Evans, J., Kenning, T., Farrell, C., Kshettry, V. (eds) Endoscopic and Keyhole Cranial Base Surgery . Springer, Cham. https://doi.org/10.1007/978-3-319-64379-3_4

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  • DOI: https://doi.org/10.1007/978-3-319-64379-3_4

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  • Publisher Name: Springer, Cham

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  • Online ISBN: 978-3-319-64379-3

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