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Ganglioglioma

  • Chapter
Oncology of CNS Tumors

Abstract

The term ganglioglioma was first coined by Perkins in 1926 to refer to an intracranial tumor composed of both neoplastic astrocytes and atypical ganglion cells. Gangliogliomas were then described by Cushing in his monograph published in 1927 and by Courville in 1930, who provided the first review published on 20 cases [24]. According to subsequent reports, these tumors accounted for an incidence of 0.3–0.97% of all central nervous system (CNS) tumors [10, 24]. Recent studies, however, suggest that gangliogliomas are not as uncommon as previously thought. With the more extensive use of magnetic resonance imaging (MRI) and improved sensitivity and accuracy of histological diagnosis, the incidence of gangliogliomas is actually believed to range between 1.3% and 10% of all primary central nervous system neoplasms [10, 22]. They are more frequently found in children and young adults with a mean age ranging from 8.5 to 31 years, 60–80% of the patients being less than 30 years old [22]. There is a slight male preponderance in most series, though many authors report an almost equal distribution between the two sexes [7].

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Authors and Affiliations

  1. Pediatric Neurosurgery, UCSC, Policlinico Gemelli, Largo Gemelli 8, Rome, 00168, Italy

    Concezio Di Rocco

  2. Ped. Neurosurgery, Catholic University, Rome

    Gianpiero Tamburrini

Authors
  1. Concezio Di Rocco
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  2. Gianpiero Tamburrini
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Correspondence to Concezio Di Rocco .

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Editors and Affiliations

  1. Universitätsklinikum München Klinikum Großhadern Neurochirurgische Klinik, Marchioninistr. 15, München, 81377, Germany

    Jörg-Christian Tonn

  2. Universitätsklinikum Hamburg Krankenhaus Eppendorf Klinik und Poliklinik für Neurochirurgie, Martinistr. 52, Neurologie, Hamburg, 20246, Germany

    Manfred Westphal

  3. Division of Neurosurgery, The Hospital for Sick Children, 555 University Avenue Suite 1502, Toronto, ON, M5G 1X8, Canada

    James T. Rutka

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Rocco, C.D., Tamburrini, G. (2010). Ganglioglioma. In: Tonn, JC., Westphal, M., Rutka, J.T. (eds) Oncology of CNS Tumors. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-02874-8_27

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  • DOI: https://doi.org/10.1007/978-3-642-02874-8_27

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-02873-1

  • Online ISBN: 978-3-642-02874-8

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