Forms of trypanosomatida
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Different morphological forms of trypanosomatida during their life cycle
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Forms of trypanosomatida
- 1. General Parasitology Zoo-701 CRH03(02+01) Tamreez khan Roll No 39 M.Phil. Zoology 1st Semester Submitted to Dr. Sadaf Naiz Date of submission: 30-08-2021
- 2. Forms of Trypanasomatidae Presentation Outline: Introduction to trypanasomatida Characteristics of trypanasomatida Medical importance of trypanasomatida life cycle of trypanasomatida Morphology of trypanasomatida
- 3. Introduction to trypanasomatida Meaning: Trypano mean borer soma mean Body Trypanasomatida is group of flagellated protozoans (Kinetoplastid).
- 4. Characteristics of trypanasomatida Their species move like corkscrew motion. All member of this group are parasites. There are intercellular parasites. Their life cycles is mostly begin from insects. They required secondary host. Both the vertebrates and invertebrates can betheir host.
- 5. Medical importance of trypanasomatida There are three medically important diseases causes y species of trypanasomatida. 1. Leishmaniasis: leishmaniasis is the invasion of leishmania parasite in the skin, visrea and the cutaneous parts of the human and other mammals. Causes: various specie of genus Leishmaniasis are causing the leishmaniasis in which L. tropica, L.donovani, L. mexicna are mostly involved Vector: The parasite of leishmaniasis are spread through sand fly.
- 6. 02. Trypanasomiasis: it is also known as sleeping sickness. Causes: trypanasomiasis is caused by trypanosome bruci. Vector: The vector for this parasites is also an insect called tsetse fly.
- 7. 03. Chagas disease: it is also known as American Trypanasomiasis and it is tropica parasitic diseases. Causes: Chagas disease is caused by trypanosome cruzi Vector: this parasite is transmitted though Kissing bug (triatominae).
- 8. Life cycle of trypanasomatida All the trypanasomatida required more than one host. It is mostly live in the digestive tracts of blood sucking insects and blood stream of vertebrates. They go through different morphological structure at least two from some time many in their life structure. The promastigote and epimastigote are found in the insects tracts. Tropomastigote form in the mammalian bloodstream. Amastigote from in the intracellular environment.
- 9. Morphology of trypanosomatida The trypanosomatida appear in different Morphological form during their life Cycle. Their morphological forms are based on The length, position and attachment of Flagellum. All trypanosomatida species have Single nucleus.
- 10. Amastigote (leishmanial). Leishmania amastigotes are particularly small and are among the smallest eukaryotic cells. The flagellum is very short, projecting only slightly beyond the flagellar pocket. Amastigotes are a common morphology during an intracellular lifecycle stage in a mammalian host. All Leishmania have an amastigote stage of the lifecycle.
- 12. Promastigote The promastigote form is a common morphology in the insect host. The flagellum is found anterior of nucleus and flagellum not attached to the cell body. The kinetoplast is located in front of the nucleus, near the anterior end of the body.
- 14. Epimastigote The flagellum exits the cell anterior of nucleus and is connected to the cell body for part of its length by an undulating membrane. The kinetoplast is located between the nucleus and the anterior end. Epimastigotes are a common form in the insect host and Crithidia and Blastocrithidia, both parasites of insects, exhibit this form during their life cycles.
- 15. Trypomastigote (trypanosomal) In trypomastigotes the kinetoplast is near the posterior end of the body, and the flagellum lies attached to the cell body for most of its length by an undulating membrane. This stage is characteristic of the genus Trypanosoma in the mammalian host bloodstream as well as infective metacyclic stages in the fly vector.