Mycobacterium tuberculosis and atypical mycobacteria
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Mycobacterium tuberculosis and Atypical Mycobacteria
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Mycobacterium tuberculosis and atypical mycobacteria
- 1. Mycobacterium tuberculosis and atypical Mycobacteria BDS 3-4-15
- 4. Mycobacterium tuberculosis Transmission and Epidemiology 1.7 Million Deaths 9 Million New Cases Mycobacterium bovis Intestinal Tuberculosis
- 5. Mycobacterium tuberculosis Growth & Medium
- 6. Mycobacterium tuberculosis Cell Wall & Cord Factor Trehalose Dimycolate
- 7. Mycobacterium tuberculosis Pathogenesis Lesions 1. Exudative Lesions 2. Granulomatous Lesions
- 9. Diagnosis of tuberculosis Latent Infection Active tuberculosis Smear examination Solid and liquid culture Identification Susceptibility testing methods TST IFN- techniques Molecular methods -Detection -Identification -Detection of resistance 9
- 11. Atypical Mycobacteria Runyon’s Classification 1. Photochromogens 2. Schotochromogens 3. Nonchromogens 4. Rapid Growers
- 12. Group 1 Photochromogens Mycobacterium kansasi and M. marinum M. kansasii • Causes lung disease clinically resembling tuberculosis. • It is susceptible to the standard antituberculosis drugs. Mycobacterium marinum • Causes "swimming pool or "fish tank” granuloma . • These granulomatous, ulcerating lesions occur in the skin at the site of abrasions incurred at swimming pools and aquariums. • Treatment with a tetracyclines
- 13. Group 2 Scotochromogens Mycobacterium scrofulacium • Causes lymphadenitis
- 14. Group 3 Nonchromochromogens Mycobacterium avium and M. intracellulare Mycobacterium avium intracellulare complex • Cause tuberculosis like illness usually in immunocompromised patients • Highly resistant to antituberculosis drugs
- 15. Group 4 Rapid Growers Mycobacterium fortuitum and M. chelonei Mycobacterium fortuitum-chelonei complex • Rarely cause human disease. • Infections occur in immunocompomised patients and patients with catheters or prosthetic joints. • Resistant to antituberculous drugs.
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