The principles of clinical cytogenetics
In this thoroughly revised and expanded third edition of the highly praised classic, The Principles of Clinical Cytogenetics, a panel of hands-on experts update their descriptions of the basic concepts and interpretations involved in chromosome analysis to include the many advances that have occurred in the field. Among the highlights are a full chapter devoted to advances in chromosome microarray, soon to become a standard of care in this field, as well as an update on chromosome nomenclature as reflected in ISCN 2009
Internet Resources
1 online resource (561 pages)
9781441916884, 9781441916877, 1441916881, 1441916873
836407073
SECTION 1 - Basic Concepts and Background1. History of Clinical CytogeneticsSteven L. Gersen2. DNA, Chromosomes, and Cell Division Martha B. Keagle3. Human Chromosome Nomenclature: An Overview and Definition of TermsMarilyn L. Slovak, Aaron Theisen, and Lisa G. ShafferSECTION II - Examining and Analyzing Chromosomes4. Basic Cytogenetics Laboratory ProceduresMartha B. Keagle and Steven L. Gersen5. The Essentials of Light MicroscopyNathan Claxton and Stephen Ross6. Quality Control & Quality AssuranceMartha B. Keagle7. Instrumentation in the Cytogenetics LaboratorySteven L. GersenSECTION III – Clinical Cytogenetics8. Autosomal AneuploidyJin-Chen C. Wang9. Structural Chromosome RearrangementsKathleen Kaiser-Rogers and Kathleen Rao10. Sex Chromosomes, Sex Chromosome Disorders, and Disorders of Sex DevelopmentCynthia M. Powell11. The Cytogenetics of InfertilityLinda Marie Randolph12. Prenatal CytogeneticsLinda Marie Randolph13. The Cytogenetics of Spontaneous AbortionSolveig M. V. Pflueger14. Chromosome InstabilityXiao-Xiang ZhangSECTION IV – Cancer Cytogenetics15. The Cytogenetics of Hematologic NeoplasmsAurelia Meloni-Ehrig16. The Cytogenetics of Solid Tumors Linda D. Cooley and Kathleen S. WilsonSECTION V - Adjunct Technologies17. Fluorescence in situ Hybridization (FISH)Daynna J. Wolff18. Microarray-Based CytogeneticsLisa G. ShafferSECTION VI – Beyond Chromosomes19. Fragile X: A Family of Disorders: Changing Phenotype and Molecular GeneticsElaine B. Spector 20. Genomic Imprinting and Uniparental DisomyJin-Chen C. Wang21. Genetic CounselingSarah Hutchings Clark
English