Fritz Hoffmann (right), founder of F. Hoffmann-La Roche & Co., with chemist Emil Barell in 1898. 

Fritz Hoffmann (right), founder of F. Hoffmann-La Roche & Co., with chemist Emil Barell in 1898. 

Source: Roche

Switzerland’s Biggest Family Fortune Has Prospered for 124 Years

The family behind drug maker Roche has neatly navigated the pitfalls of generational change.

The timing was precise, the choreography immaculate: with two deft maneuvers, a new generation of the Oeri-Hoffmann family marked its growing influence over the wealthiest dynasty in Switzerland.

First, seven members of the fifth generation late last year joined the clan’s shareholder pool, which oversees a $25 billion stake in pharmaceuticals giant Roche Holding AG. Then, in March, another member of that generation, Joerg Duschmale, replaced his uncle on the drugmaker’s board.