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Methacetin

CAS No.
51-66-1
Chemical Name:
Methacetin
Synonyms
N-(4-METHOXYPHENYL)ACETAMIDE;Metacetin;METHACETIN;acetaniside;p-acetaniside;4-Acetaniside;AURORA KA-3672;Acet-p-anisidin;p-Acetanasidine;MethacetinN-(4-
CBNumber:
CB6310310
Molecular Formula:
C9H11NO2
Molecular Weight:
165.19
MDL Number:
MFCD00014963
MOL File:
51-66-1.mol
Last updated:2023-05-15 10:43:34

Methacetin Properties

Melting point 128-130 °C(lit.)
Boiling point 293.03°C (rough estimate)
Density 1.1603 (rough estimate)
refractive index 1.5839 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility Chloroform (Slightly), Methanol (Slightly)
form Crystalline
pka 14.53±0.70(Predicted)
color White
Water Solubility 0.42 g/100 mL (20 ºC)
Merck 14,51
BRN 387887
Stability Hygroscopic
CAS DataBase Reference 51-66-1(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII 13E468TFHP
NIST Chemistry Reference N-(4-Methoxyphenyl)acetic acid amide(51-66-1)
EPA Substance Registry System Acetamide, N-(4-methoxyphenyl)- (51-66-1)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312+P330-P501-P301+P312a-P330-P501a
Hazard Codes  Xn,Xi
Risk Statements  22-36/38
Safety Statements  36-37/39-26
WGK Germany  1
RTECS  AE8290000
TSCA  Yes
HS Code  29242990
Toxicity LD50 orl-mus: 1190 mg/kg TXAPA9 19,20,71
NFPA 704
0
2 0

Methacetin price More Price(15)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical A0019 p-Acetanisidide >98.0%(HPLC)(N) 51-66-1 25g $83 2024-03-01 Buy
TCI Chemical A0019 p-Acetanisidide >98.0%(HPLC)(N) 51-66-1 100g $203 2024-03-01 Buy
TRC M258770 Methacetin 51-66-1 500mg $80 2021-12-16 Buy
Oakwood 091550 N-(4-Methoxyphenyl)acetamide 98% 51-66-1 5g $15 2021-12-16 Buy
Matrix Scientific 136397 N-(4-Methoxyphenyl)acetamide 95%+ 51-66-1 1g $101 2021-12-16 Buy
Product number Packaging Price Buy
A0019 25g $83 Buy
A0019 100g $203 Buy
M258770 500mg $80 Buy
091550 5g $15 Buy
136397 1g $101 Buy

Methacetin Chemical Properties,Uses,Production

Chemical Properties

LIGHT BEIGE CRYSTALLINE POWDER

Uses

Methacetin is evaluated in a breath test to predict early liver disfunction due to valproic acid and other cause. Methacetin breath test (MBT) is a rapid, non-invasive assessment of liver function in acute severe liver disease and a potential key tool in future dignosis.

Definition

ChEBI: Methacetin is a member of the class of acetamides that is paracetamol in which the hydrogen of phenolic hydroxy group has been replaced by a methyl group. It is a member of acetamides and an aromatic ether. It is functionally related to a p-anisidine and a paracetamol.

Synthesis Reference(s)

Journal of the American Chemical Society, 89, p. 7131, 1967 DOI: 10.1021/ja01002a061
The Journal of Organic Chemistry, 42, p. 3755, 1977
Organic Syntheses, Coll. Vol. 3, p. 661, 1955

Safety Profile

Moderately toxic by ingestion andother unspecified routes. When heated to decomposition itemits toxic fumes of NOx.

Global( 241)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Daken Advanced Materials Co.,Ltd
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career henan chemical co
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SIMAGCHEM CORP
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0551-65418671 sales@tnjchem.com China 34572 58

View Lastest Price from Methacetin manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Methacetin pictures 2023-03-29 Methacetin
51-66-1
US $30.00-10.00 / kg 10kg 99% 100000kg Hebei Guanlang Biotechnology Co,.LTD
Methacetin pictures 2019-07-14 Methacetin
51-66-1
US $1.00 / KG 1KG 99% 100kg Career Henan Chemical Co
  • Methacetin pictures
  • Methacetin
    51-66-1
  • US $30.00-10.00 / kg
  • 99%
  • Hebei Guanlang Biotechnology Co,.LTD
  • Methacetin pictures
  • Methacetin
    51-66-1
  • US $1.00 / KG
  • 99%
  • Career Henan Chemical Co
p-Acetanasidine~N-(Methoxyphenyl)acetamide p-Acetanasidine p-Acetoanisidide 4'-Methoxyacetanilide, 99+% n-(methoxyphenyl)acetamide p-acetaniside acetaniside p-acetylanisidine PARA-ACETANISIDIDE Acet-p-anisidin 4-METHOXYACETANILIDE / P-ACETANASIDINE MethacetinN-(4- Methoxyphenyl)acetamide p-Acetanisidide165.19 4'-Methoxyacetanilide, 98+% p-Acetanisidide N-(4-Methoxyphenyl) Acetamide, N-(4-methoxyphenyl)- Acetamide,N-(4-methoxyphenyl)- Acetanilide, 4'-methoxy- Acetanilide, 4-methoxy Aceto-p-anisidide Aceto-p-anisidine ethanamide,N-(4-methoxyphenyl)- Metacetin n-(4-methoxyphenyl)-acetamid N-(4-methoxyphenyl)ethanamide 4-(Acetylamino)anisole 4’-methoxy-acetanilid 4-Acetaniside N-(p-Methoxyphenyl)acetamide N-Acetyl-p-methoxyaniline p-Acetamidoanisole METHACETIN LABOTEST-BB LT00053555 AURORA KA-3672 P-ACETANISIDIDE P-ACETANISIDINE P-METHOXYACETANILIDE N-ACETYL-P-ANISIDINE 4'-METHOXYACETANILIDE 4-METHOXYACETANILIDE 4-ACETANISIDIDE 4-ACETANISIDINE 4-ACETAMIDOANISOLE ACETYL-P-ANISIDINE p-Acetanisidide > 4-Methoxy acetanlide TIANFU-CHEM CAS NO.51-66-1 N-(4-Methoxyphenyl)acetamide N-(4-METHOXYPHENYL)ACETAMIDE Hydrocortisone-d3(Cortisol-d3) 51-66-1 CH3OC6H4NHCOCH3 Protected Amines Nitrogen Compounds Organic Building Blocks Building Blocks Intermediates of Dyes and Pigments