Causes of Orthopnea - Differential Diagnosis Framework
 • Fear and Anxiety
 • Pleural Effusion
 • Ascites
 • COPD
 • Hypothyroidism/Hyperthyroidism
 • URTI
 • Pulmonary Edema
 • Severe Pneumonia
 • Obesity/SIeep apnea
 • Hypothyroidism: Cardiogenic/Noncardicgenic pulmonary edema, Diaphragmatic weakness
 • Hyperthyroidism: Cardiogenic pulmonary edema, Diaphragmatic pulmonary edema
 • Bilateral Diaphragmatic paralysis: Trauma, Surgery, Radiation, Cervical manipulation, CNS lesion (ALS, MS, Polio), PNS lesion (Brachial plexus neuropathy, GBS, CIDP), Myopathies, Compressive mediastinal tumors

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