Causes of Peptic Ulcer Disease
 • H. Pylori
 • NSAIDs
 • Gastric adenocarcinoma
 • Gastric lymphoma
 • Local drug irritation
 • Irritation at the neck of a hiatus hernia (Cameron's ulcer)
 • Idiopathic
 • Anastomotic ulceration after previous gastric surgery
 • After radiotherapy
 • Zollinger-Ellison syndrome (gastrinoma) - particularly for duodenal ulcers
 • Multiple endocrine neoplasia type-I
 • Hyperparathyroidism without multiple endocrine neoplasia type-I
 • Systemic mastocytosis
 • Severe systemic illness stress ulcers (Cushing's ulcer)
 • Idiopathic eosinophilic and lymphocytic gastritis
 • Duodenal Crohn's disease
 • Coeliac axis stenosis
 • Hepatic artery chemotherapy
 • Prescribed medicines including bisphosphonates, sirolimus, mycophenolate, corticosteroids (when combined with NSAIDs)
 • Recreational drugs including crack cocaine

#PUD #Peptic #Ulcer #Disease #Causes #differential #diagnosis