Honey Habi’s Post

Can expression of the PD-1 protein help differentiate inflammatory bowel disease (IBD) from other inflammation-related diseases, which is often challenging? The science on it remains inconclusive, but a new study describes results supporting the role of PD-1 expression as an indicator. Read the paper: PD-1-positive cells contribute to the diagnosis of inflammatory bowel disease and can aid in predicting response to vedolizumab Min Kyu Kim, et al. https://lnkd.in/etPicUkd #InflammatoryBowelDisease #InflammatoryDiseases #Inflammation #OpenAccess #Publication

The #CRP test stands for C-reactive protein test. It is a blood test that measures the level of C-reactive protein (CRP) in the bloodstream. CRP is a protein produced by the liver in response to inflammation in the body. When there is inflammation present, the levels of CRP increase in the blood.📍💉🏥 The CRP test is a non-specific marker of inflammation and is often used by healthcare providers to assess the presence and severity of inflammation in various conditions. It is a relatively simple and inexpensive test, and it can be used to help diagnose and monitor a wide range of inflammatory and infectious diseases, such as:🧬💊🔬💉🧪🧫 1. Infections: Bacterial or viral infections can cause an increase in CRP levels. 2. Autoimmune diseases: Conditions like rheumatoid arthritis, lupus, and inflammatory bowel disease can lead to elevated CRP levels. 3. Cardiovascular diseases: CRP levels can be used as a marker of inflammation in conditions like atherosclerosis and coronary artery disease. 4. Tissue injury: After trauma or surgery, CRP levels may temporarily rise. 5. Cancer: Some cancers can cause increased CRP levels. 6. Monitoring response to treatment: The CRP test can also be used to monitor the effectiveness of treatment for certain conditions. #crp #infection #inflammation #prevention #hospitals

Multiple Myeloma A cancer of plasma cells. The plasma cells are a type of white blood cell in the bone marrow. With this condition, a group of plasma cells becomes cancerous and multiplies. The disease can damage the bones, immune system, kidneys and red blood cell count.People may experience: Pain areas: in the back or bones Whole body: anaemia, fatigue, or loss of appetite Also common: constipation, hypercalcemia, increased risk of infection, kidney damage, or weight lossMedications Chemotherapy, Blood transfusion, Steroid and Bone healthComplications Complications of multiple myeloma include: Infections. Having multiple myeloma lowers the body's ability to fight infections. Bone problems. Multiple myeloma can cause bone pain, thinning bones and broken bones. Kidney problems. Multiple myeloma may cause problems with the kidneys. It can lead to kidney failure. Low red blood cell count, called anemia. As myeloma cells crowd out healthy blood cells, multiple myeloma can also cause anemia and other blood problems. #snsdesignthinkers #snsinstitutions #snsdesignthinking

Pulmonary arterial hypertension (PAH) is a progressive and life-threatening disease resulting from dysfunction in lung artery endothelial cells, leading to right heart failure and death. Previous research has linked PAH-related endothelial cell dysfunction to unrepaired DNA damage. A recent study led by Sarasa Isobe, MD, PhD, and BASE Director Marlene Rabinovitch, MD, published in Nature Communications, has identified the mechanisms responsible for the unrepaired DNA damage in lung endothelial cells associated with PAH. Read more at https://lnkd.in/dHrt_TRc #stanfordcvi #stanfordmedicine #pulmonaryhypertension #cardiovasculardisease