Owen Moore’s Post

Smart Research Review: Relationship Between Endplate Defects, Modic Change, Facet Joint Degeneration, and Disc Degeneration of the Cervical Spine “Neck pain is a multidimensional phenomenon that affects as much as two-thirds or more of the general population. Among the many causes of neck pain, degeneration of the cervical disc is a common condition.” “In particular, disc height reduction, segmental kyphosis, and loss of segmental motion are related with degeneration.” “It demonstrates the change of disc height, segmental angle, and segmental motion according to the degeneration grade.” https://bit.ly/3Z9FOgS

Subjects with ankylosing spinal disorders, including diffuse idiopathic skeletal hyperostosis (DISH) and ankylosing spondylitis (AS) have a higher risk of vertebral fractures compared to patients without an ankylosed spine. Our latest systematic review on this topic was recently published in the North American Spine Society Journal: 7 studies on DISH were included (n = 1,193 patients, total fractures = 231)  pooled vertebral fracture prevalence: 22.6% (95%CI: 13.4%-33.4%) 26 studies on AS were included (n = 2,875 patients, total fractures = 460)  pooled vertebral fracture prevalence: 15.2% (95%CI: 11.6%-19.1%) Fractures in DISH were most common at the thoracolumbar junction, whereas for AS, the most common location was the mid-thoracic spine. Link to article: https://lnkd.in/dEsy939m Netanja Harlianto, Solaiman E., Jonneke Kuperus, Irene van der Horst-Bruinsma, Pim de Jong, Jorrit-Jan Verlaan

Lower motor neuron (LMN) lesions and upper motor neuron (UMN) lesions refer to damage or dysfunction in different parts of the nervous system, leading to distinct clinical manifestations: 1. **Lower Motor Neuron (LMN) Lesion:** - Location: Damage occurs at or below the level of the anterior horn cell in the spinal cord or the motor nuclei in the brainstem. - Effects: Results in weakness, atrophy, hyporeflexia (decreased reflexes), and fasciculations (muscle twitches) in the muscles supplied by the affected nerve or nerves. - Example Conditions: Peripheral nerve injuries, spinal cord injuries affecting the anterior horn cells, motor neuron diseases like ALS (amyotrophic lateral sclerosis). 2. **Upper Motor Neuron (UMN) Lesion:** - Location: Damage occurs along the descending motor pathways above the level of the anterior horn cell. - Effects: Leads to spasticity (increased muscle tone), hyperreflexia (increased reflexes), clonus (repetitive rhythmic contractions), and weakness, usually in a more widespread distribution compared to LMN lesions. - Example Conditions: Stroke, multiple sclerosis, cerebral palsy, spinal cord injury. In summary, while both LMN and UMN lesions can cause weakness, they differ in their specific clinical signs and underlying anatomical locations of damage. #RaiseAgainstAutism #PinnacleSaysItAll #PinnacleBloomsNetwork #1AutismTherapyCentresNetwork

Paraneoplastic and limbic encephalitis are two syndromes with well described clinicopathological features that are likely immune-mediated (Dropcho, 2004). It typically causes short-term memory loss, seizures, irritability, depression and cognitive decline Anti-Ma associated encephalitis is a paraneoplastic neurological syndrome (PNS) characterized by isolated or combined limbic, diencephalic, or brainstem dysfunction. However, in most cases the clinical pictures are different from those of classical PNS and this creates a potential risk of underdiagnosis. It has been reported that less than 30% of the patients with anti-Ma2 ,exhibit clinical presentations typical of the classical description of LE. Of the remaining, many exhibit excessive daytime sleepiness, vertical ophthalmoparesis, or both associated with LE, because of frequent involvement of the diencephalon and/or upper brainstem. Guarantors of Brain MRI image- Axial FLAIR showing midbrain, thalmi and bi-temporal lobe hyper intense signals

Can a Disc Cause Pain A disc can herniate backward pressing on the spinal cord or herniate lateral of center and press on a nerve root. These findings can cause radicular pain, loss of strength and sensation and altered reflexes. But can a disc cause pain without these neurological findings? According to an article in Journal of Anatomy, authored by Polly Lama, in 2018, nerves and blood vessels can migrate inward towards the damaged inner tissue of the nucleus polposus. The nerves that originate in the outer layers of the annulus fibrosis and vertebral end plates grow inward through disrupted damaged tissue.  Damage from slow degeneration of trauma must have previously occurred.  These nerves are pain sensitive and can be the origin of chronic discogenic (disc origin) pain that is often present in degenerated discs. Soooo, spine pain without herniation can originate in disc. 1.     An MRI can detect a herniated or degenerated disc and can show disc damage. 2.     The distribution of pain can match known disc pain patterns. These two findings offer evidence to justify a discogenic pain diagnosis. #chiropractic #autoaccident