Bacteria have previously been assumed to cope with environmental stress by tuning their total number of active ribosomes. Instead, a study in this issue of Nature Microbiology shows that from a heterogeneous pool of ribosomes, Vibrio vulnificus uses ribosomes with a particular ribosomal RNA variant to translate upregulated stress response mRNAs.
This is a preview of subscription content, access via your institution
Access options
Access Nature and 54 other Nature Portfolio journals
Get Nature+, our best-value online-access subscription
$29.99 / 30 days
cancel any time
Subscribe to this journal
Receive 12 digital issues and online access to articles
$119.00 per year
only $9.92 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Palade, G. E. J. Biophys. Biochem. Cy. 1, 59–68 (1955).
Noller, H. F. Cold Spring Harb. Perspect. Biol. 4, 1–14 (2012).
Khaitovich, P., Mankin, A. S., Green, R., Lancaster, L. & Noller, H. F. Proc. Natl Acad. Sci. USA 96, 85–90 (1999).
Genuth, N. R. & Barna, M. Mol. Cell 71, 364–374 (2018).
Woese, C. R. Microbiol. Rev. 51, 221–271 (1987).
Gutell, R. R. RNA Biol. 11, 254–272 (2014).
Pei, A. Y. et al. Appl. Environ. Microbiol. 76, 3886–3897 (2010).
Sun, D. L., Jiang, X., Wu, Q. L. & Zhou, N. Y. Appl. Environ. Microb. 79, 5962–5969 (2013).
Gunderson, J. H. et al. Science 238, 933–937 (1987).
Song, W. et al. Nat. Microbiol. https://doi.org/10.1038/s41564-018-0341-1 (2019).
Dai, X. et al. Nat. Microbiol. 2, 1–9 (2016).
Steitz, J. A. & Jakes, K. Proc. Natl Acad. Sci. USA 72, 4734–4738 (1975).
Kurylo, C. M. et al. Cell Rep. 25, 236–248 (2018).
Parks, M. M. et al. Sci. Adv. 4, eaao0665 (2018).
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
The authors declare no competing interests.
Rights and permissions
About this article
Cite this article
Leppek, K., Barna, M. An rRNA variant to deal with stress. Nat Microbiol 4, 382–383 (2019). https://doi.org/10.1038/s41564-019-0396-7
Published:
Issue Date:
DOI: https://doi.org/10.1038/s41564-019-0396-7