The accurate homogeneous differentiation of human induced pluripotent stem cells into chondrocytes is crucial for cartilage regenerative therapies. Discovery of the signalling pathways responsible for the differentiation of unwanted cell types during in vitro chondrogenesis could herald a breakthrough for in vitro cartilage generation.
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Rim, Y.A., Ju, J.H. Streamlining cell fate decisions during chondrogenesis. Nat Rev Rheumatol 17, 313–314 (2021). https://doi.org/10.1038/s41584-021-00604-3
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DOI: https://doi.org/10.1038/s41584-021-00604-3