General
Preferred name
AMPEROZIDE
Synonyms
AMPEROZIDE HYDROCHLORIDE ()
Amperozida ()
Amperozide HCl ()
P&D ID
PD004521
CAS
75558-90-6
75529-73-6
Tags
natural product
drug
available
Drug indication
Alcohol dependence
Drug Status
experimental
approved
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Atypical antipsychotic drug with high affinity for serotonin receptors and low affinity for D2 dopamine receptors
(LOPAC library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
1
Organisms
2
Compound Sets
12
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMatrix
Ki Database
LOPAC library
Novartis Chemogenetic Library (NIBR MoA Box)
NPC Screening Collection
ReFrame library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
40
Molecular Weight
401.23
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
1
Rotatable Bonds
7
Ring Count
3
Aromatic Ring Count
2
cLogP
4.22
TPSA
35.58
Fraction CSP3
0.43
Chiral centers
0.0
Largest ring
6.0
QED
0.75
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Member status
member
MOA
"5-HT2A Antagonists
Dopamine D2 Antagonists"
5-HT2A Antagonists
Dopamine D2 Antagonists
Dopamine Receptor antagonist
Target
FAAH, HTR2A
Indication
psychosis
Source data
