Acute lymphoblastic leukemia (ALL) is a rare, aggressive cancer in which the bone marrow produces excessive numbers of lymphoblasts (abnormal immature lymphocytes) that replace normal bone marrow elements responsible for the production of healthy blood cells. This process leads to declining numbers of functional platelets, erythrocytes, and neutrophils, resulting in the clinical manifestations of ALL.1…
Acute lymphocytic leukemia (ALL) is a cancer of B or T lymphoblasts characterized by the unregulated proliferation of aberrant, immature lymphocytes and their progenitors. This process ultimately results in the replacement of bone marrow components and other lymphoid organs, giving rise to a distinctive disease pattern.1 An accurate and timely cancer diagnosis is critical to…
Acute lymphoblastic leukemia (ALL) is an aggressive malignancy of B or T lymphoblasts that is characterized by an uncontrolled proliferation of abnormal and immature lymphocytes and their progenitors.1 ALL can develop in both children and adults, and symptoms of this malignancy include fever, fatigue, bone pain, arthralgia, headache, and vomiting. The diagnosis of ALL may…
Acute lymphoblastic leukemia (ALL), also known as acute lymphocytic leukemia, is a rare, aggressive hematologic neoplasm characterized by the excessive production of immature lymphocytes (lymphoblasts) in the bone marrow.1 Abnormal immature lymphoblasts quickly replace healthy progenitor cells in the bone marrow and disrupt the production of normal blood cells,1 including platelets, erythrocytes, and neutrophils.2 The…
Acute lymphoblastic leukemia (ALL) is a type of blood cancer characterized by the overproduction of immature and abnormal lymphocytes and their progenitors.1 It is regarded to be the most common childhood cancer, although it also affects adults. A gradual increase in ALL incidence has been reported with rates of about 3.3 cases per 100,000 children.1-3…
Acute lymphoblastic leukemia (ALL), also called acute lymphocytic leukemia, is a rare, aggressive hematologic neoplasm characterized by the rapid proliferation of immature B- or T-lymphocytes (lymphoblasts) in the bone marrow. Cancerous lymphoblasts quickly replace healthy stem cells, decreasing the production of functional blood cells and causing symptoms of anemia, neutropenia, and thrombocytopenia.1 ALL is the…
Acute lymphoblastic leukemia (ALL), also known as acute lymphocytic leukemia, is a rare cancer, accounting for less than 0.5% of all cancers diagnosed in the United States.1 ALL accounts for approximately 2% of all lymphoid neoplasms diagnosed in the United States.2 Incidence and Prevalence of ALL US Incidence and Prevalence of ALL According to the…
Acute lymphoblastic leukemia (ALL), also called acute lymphocytic leukemia, is an aggressive cancer characterized by the uncontrolled proliferation of abnormal, immature lymphocytes (lymphoblasts), which are lymphoid progenitor cells. These rapidly proliferating abnormal cells accumulate and replace normal cells in the bone marrow and peripheral blood.1,2 The proliferative process, which favors survival of the cancer cells,…
