2-Aminopurine (CAS 452-06-2)

2-Aminopurine is an inhibitor of PKR and a chemical compound with diverse applications in scientific research. It is an organic molecule that belongs to the purine family, which is a class of compounds commonly found in nucleotides, DNA, and RNA. 2-Aminopurine has been extensively studied due to its unique properties and versatility. One of its notable characteristics is its fluorescence properties, which make it a valuable tool in fluorescence spectroscopy and imaging techniques. Its fluorescence emission can be modulated by various factors such as pH, solvent polarity, and interactions with other molecules. This property has enabled researchers to investigate molecular interactions, enzymatic activity, and DNA/protein interactions. Furthermore, 2-Aminopurine has been used in studies related to DNA mutagenesis and repair. Due to its structural similarity to adenine, it can be incorporated into DNA strands during replication, leading to altered base-pairing and potential mutations. This property has allowed researchers to explore the effects of specific DNA lesions and repair mechanisms. In addition, 2-Aminopurine has been utilized as a molecular probe in various fields, including medicinal chemistry, biochemistry, and genetics. Its ability to interact with specific proteins and nucleic acids has facilitated the characterization of binding sites, structural changes, and enzymatic activities. Overall, 2-Aminopurine serves as a versatile tool in scientific research, enabling investigations into fluorescence-based techniques, DNA dynamics, mutagenesis, and molecular interactions. Its broad range of applications continues to contribute to our understanding of biological processes and the development of new diagnostic and therapeutic approaches.

References:

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