For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Cefonicid sodium is a broadspectrum cephalosporin antibiotic which inhibits the formation of the bacterial cell wall. Studies suggest that Cefonicid sodium can inhibit the carnitine/carnitine antiport when it is added internally and externally to proteoliposomes. It is known that the molecule contains various electroactive groups that can be detected using adsorptive square-wave stripping voltammetry. In addition, the compound can be detected in solution using UV spectroscopy at 265 nm. Studies indicate that Cefonicid sodium is effective against Escherichia coli, Klebsiella, Citrobacter, Enterobacter, indole-negative Proteus, and Providencia.
References:
1. Grappel, S.F., et al. 1980. J. Antibiot. 33: 85-87. PMID: 7372555 2. Dudley, M.N., et al. 1984. Clin Pharm. 3: 23-32. PMID: 6365414 3. Radi, A., et al. 2003. J Pharm Biomed Anal. 31: 1041-1046. PMID: 12667920 4. Pochini, L., et al. 2008. Chem. Biol. Interact. 173: 187-194. PMID: 18452908
Appearance :
Powder
Physical State :
Solid
Solubility :
Soluble in water, DMSO, and methanol.
Storage :
Store at 4° C
Melting Point :
>184° C (dec.)
Refractive Index :
n20D 1.85 (Predicted)
Optical Activity :
α20D -46.3°, c = 0.20 in methanol
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.