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Maleic hydrazide (CAS 123-33-1)

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CAS Number:
123-33-1
Molecular Weight:
112.09
Molecular Formula:
C4H4N2O2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

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Maleic hydrazide is a water-insoluble pyridazinone compound with diverse applications. It serves as both a herbicide and a plant growth regulator, making it valuable in agricultural practices. Additionally, maleic hydrazide is utilized to control the unwanted sprouting or suckering of tobacco plants.

References:

  1. Maleic hydrazide as an antiauxin in plants.  |  LEOPOLD, AC. and KLEIN, WH. 1951. Science. 114: 9-10. PMID: 14854880
  2. Determination of maleic hydrazide residues in cured tobacco by gas chromatography.  |  Renaud, JM., et al. 1992. J Chromatogr. 604: 243-6. PMID: 1517350
  3. The Fate of maleic hydrazide on tobacco during smoking.  |  Zhang, H., et al. 2012. ScientificWorldJournal. 2012: 451471. PMID: 23193377
  4. Maleic hydrazide: sprout suppression of potatoes in the field.  |  De Blauwer, V., et al. 2012. Commun Agric Appl Biol Sci. 77: 343-51. PMID: 23878989
  5. Cytotoxic effects of etephon and maleic hydrazide in Vero, Hep2, HepG2 cells.  |  Yurdakok, B., et al. 2014. Drug Chem Toxicol. 37: 459-65. PMID: 24495230
  6. Use of autoclave extraction and liquid chromatography with tandem mass spectrometry for determination of maleic hydrazide residues in tobacco.  |  Deng, H., et al. 2019. J Sep Sci. 42: 2390-2397. PMID: 31038270
  7. Maleic hydrazide: should the Delaney amendment apply to its use?  |  Haley, TJ. 1977. J Toxicol Environ Health. 2: 1085-94. PMID: 325222
  8. Maleic hydrazide elicits global transcriptomic changes in chemically topped tobacco to influence shoot bud development.  |  Singh, SK., et al. 2020. Planta. 252: 64. PMID: 32968874
  9. Intelligent analysis of maleic hydrazide using a simple electrochemical sensor coupled with machine learning.  |  Xu, L., et al. 2021. Anal Methods. 13: 4662-4673. PMID: 34546231
  10. Maleic hydrazide residues in tobacco and their toxicological implications.  |  Meyer, SA., et al. 1987. Rev Environ Contam Toxicol. 98: 43-60. PMID: 3554416
  11. Cytotoxic effects of maleic hydrazide.  |  Swietlińska, Z. and Zuk, J. 1978. Mutat Res. 55: 15-30. PMID: 368621
  12. Maleic hydrazide prompting growth and delaying senescence of mother frond in S. Polyrriza 7498.  |  Wang, J., et al. 2023. J Plant Physiol. 284: 153966. PMID: 36965290
  13. Mode of action of maleic hydrazide in relation to residues in crops and soils.  |  Hoffman, I. and Parups, EV. 1964. Residue Rev. 7: 96-113. PMID: 4865264
  14. A review of environmental and health risks of maleic hydrazide.  |  Ponnampalam, R., et al. 1983. Regul Toxicol Pharmacol. 3: 38-47. PMID: 6351180
  15. Maleic hydrazide, carcinogenicity study in rats.  |  Van der Heijden, CA., et al. 1981. Toxicology. 19: 139-50. PMID: 7268786