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Lucid interval

In emergency medicine, a lucid interval is


a temporary improvement in a patient's
condition after a traumatic brain injury,
after which the condition deteriorates. A
lucid interval is especially indicative of an
epidural hematoma. An estimated 20 to
50% of patients with epidural hematoma
experience such a lucid interval.[1][2]

Indications
When related to hemorrhage, the lucid
interval occurs after the patient is knocked
out by the initial concussive force of the
trauma, then lapses into unconsciousness
again after recovery when bleeding causes
the hematoma to expand past the extent
for which the body can compensate.[3]
After the injury, the patient is momentarily
dazed or knocked out, and then becomes
relatively lucid for a period of time which
can last minutes or hours.[3] Thereafter
there is rapid decline as the blood collects
within the skull, causing a rise in
intracranial pressure, which damages brain
tissue. In addition, some patients may
develop "pseudoaneurysms" after trauma
which can eventually burst and bleed, a
factor which might account for the delay in
loss of consciousness.[4]

Because a patient may have a lucid


interval, any significant head trauma is
regarded as a medical emergency and
receives emergency medical treatment
even if the patient is conscious.

Delayed cerebral edema, a very serious


and potentially fatal condition in which the
brain swells dramatically, may follow a
lucid interval that occurs after a minor
head trauma.[5]
Lucid intervals may also occur in
conditions other than traumatic brain
injury, such as heat stroke[6] and the
postictal phase after a seizure in epileptic
patients.[7]

See also
Natasha Richardson
Mark Donohue

References
1. Kushner D (1998). "Mild Traumatic Brain
Injury: Toward Understanding
Manifestations and Treatment" . Archives
of Internal Medicine. 158 (15): 1617–1624.
doi:10.1001/archinte.158.15.1617 .
PMID 9701095 . Archived from the original
on 2008-05-14.
2. Kushner DS (2001). "Concussion in
Sports: Minimizing the Risk for
Complications" . American Family
Physician. 64 (6): 1007–14.
PMID 11578022 .
3. Valadka AB (2004). "Injury to the
cranium". In Moore EJ, Feliciano DV, Mattox
KL. Trauma . New York: McGraw-Hill,
Medical Pub. Division. pp. 385–406.
ISBN 0-07-137069-2. Retrieved 2008-08-15.
4. Roski, RA; Owen M; White RJ; Takaoka Y;
Bellon EM (1981). "Middle meningeal artery
trauma". Surgical Neurology. Elsevier
Science Inc. 17 (3): 200–203.
doi:10.1016/0090-3019(82)90280-4 .
PMID 7079938 .
5. Kors, EE; Terwindt GM; Vermeulen FL;
Fitzsimons RB; Jardine PE; Heywood P;
Love S; van den Maagdenberg AM; Haan J;
Frants RR; Ferrari MD (2001). "Delayed
cerebral edema and fatal coma after minor
head trauma: role of the CACNA1A calcium
channel subunit gene and relationship with
familial hemiplegic migraine". Annals of
Neurology. 49 (6): 753–760.
doi:10.1002/ana.1031 . PMID 11409427 .
6. Casa, DJ; Armstrong LE; Ganio MS;
Yeargin SW (2005). "Exertional heat stroke
in competitive athletes". Current Sports
Medicine Reports. 4 (6): 309–317.
doi:10.1097/01.csmr.0000306292.64954.d
a . PMID 16282032 .
7. Nishida, T; Kudo T; Nakamura F;
Yoshimura M; Matsuda K; Yagi K (2005).
"Postictal mania associated with frontal
lobe epilepsy". Epilepsy & Behavior. 6 (1):
102–110.
doi:10.1016/j.yebeh.2004.11.009 .
PMID 15652742 .

External links
Medpix.com discussion of lucid
interval . Retrieved on February 6, 2007.

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