Gallbladder is a small organ located under the liver. Its function is to aid in digestion of food by storing and secreting bile (a digestive juice) into the small intestine when food enters there. Gallstone Disease may develop when there is too much cholesterol or bilirubin inside gallbladder secreted by the liver. To know the signs & symptoms of Gallstone Disease. visit at http://gisurgery.info
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Gallstone Disease
1. Gallstone Disease
Introduction
Gallbladder is a small organ located under the liver. Its function is to aid in
digestion of food by storing and secreting bile (a digestive juice) into the small
intestine when food enters there. Bile is a digestive fluid that is produced by
the liver and is made up of several substances including cholesterol, bilirubin
and bile salts.
Gallstones are pieces of solid material that form in the gallbladder. Sometimes
the cholesterol and pigments present in bile result in formation of hard
particles. These stones range in size from tiny sand grains to large ones the
size of golf balls.
There are mainly two types of gallstones that can be formed inside gallbladder:
Cholesterol stones: these are the most common type of gallstones, often
appears yellow green in color. Almost 80% of the gallstones are cholesterol
stones.
Pigment Stones: it is usually formed due to the large amount of bilirubin
inside gallbladder. They are dark brown or black in color.
Signs & Symptoms
• Sudden and rapid pain in the upper abdomen and upper back lasting several
minutes to few hours
• Back pain between the shoulder blades
• Pain in the right shoulder
• Nausea & vomiting
• Other gastrointestinal problems like - Bloating, indigestion, heartburn, gas etc
Causes
Gallstone may develop when there is too much cholesterol or bilirubin inside
gallbladder secreted by the liver.
Bile usually dissolves or break down cholesterol however if the liver produces
more cholesterols than the bile can dissolve it results in formation of hard
stones called cholesterol gall stones.
Bilirubin is a chemical that is produced when the body breaks down old red
blood cells. In some cases such as cirrhosis of the liver and certain blood
disorders the liver produces too much bilirubin which contributes to the
gallstone formation.
2. If the gallbladder often fails to get empty completely the bile may becomes
overly concentrated leading to formation of gallstones.
Risk Factors
Following are the various risk factors of developing gallstones:
Age of above 40 years and female gender: gallstones are more common
among women and older people
Cirrhosis of liver: may cause liver to produce more cholesterol than bile can
dissolve which leads to formation of cholesterol gallstones
On low calorie diet that leads to rapid weight loss: if a person looses
weight too quickly the liver secretes extra cholesterol which may lead to
formation of gallstone. Fasting also cause the gallbladder to contract less
preventing the gallbladder from emptying completely which may leads to
concentrate the gallbladder content and ultimately gallstones
Diabetes: diabetic people tend to have higher level of triglycerides which is a
type of blood fat that increases the risk of gallstone formation
Obesity: this is one of the biggest risk factor. It can cause a rise in cholesterol
and also prevent gallbladder from preventing completely
Estrogen: it can increase cholesterol and reduce gallbladder motility. Women
who are pregnant or who take birth control pills or hormone replacement
therapy have higher levels of estrogen and are more likely to develop gallstone
Genetics: Having family history of gallstones increases your risk of developing
gallstone
Cholesterol lowering drugs: they increases the amount of cholesterol in bile
increasing the chances of developing gallstone
Complications
If the gallstone gets lodged in the neck of the gallbladder it can cause
inflammation of the gallbladder called cholecystitis which can cause severe
pain and fever.
Gallstones may get stuck in to any of the tubes that carries bile from
gallbladder to small intestine causing blockage of common bile duct. This
condition may lead to jaundice or bile duct infection.
Gallstone may put you at increased risk of developing gallbladder cancer
however the chances of gallbladder cancer are usually very small.
Diagnosis
Abdominal CT Scan: it is a digital imaging test that takes pictures of the liver
and abdominal region revealing the presence of gallstone if any.
3. Ultrasound: this test uses ultrasonic sound waves to create image of
abdominal organs which help find presence of any gallstone.
Blood tests: to look for amount of bilirubin in the blood and to determine the
functioning of liver.
Treatment
Surgery is often the first choice if there are profound symptoms of gallstone.
Laparoscopic gallbladder removal is the most common surgical technique
which involves insertion of two to three rod like instrument called laparoscope
through tiny holes on abdomen.
Drugs that dissolve gallstones caused by cholesterol can be used for those who
cannot undergo surgery however these drugs may take several years to
eliminate the gallstone.
The risk of developing gallstone can be reduced by adopting healthy lifestyle
strategies. Eat balanced diet. Avoid skipping meals. Drink sufficient amount of
water every day. Eat fiber rich diet. Maintain healthy weight etc.