2. Plan of Talk
Salmonella overview
Etiology
Transmission
Clinical signs
Post mortem lesions
Treatment
3. Plan of Talk
Salmonella overview
Etiology
Transmission
Clinical signs
Post mortem lesions
Treatment
4. Salmonella Overview
Salmonellosis is any of
several bacterial infections
caused by species of
Salmonella, ranging from
mild to serious infections.
5. Cont. …
“Salmonella”, the name, derived from Dr.
Daniel Salmon, a U.S. veterinary
surgeon, who discovered and isolated
the strain enterica or choleraesuis from
the intestine of a pig in 1885.
6. Cont. …
Rod-shaped
Gram-negative
Facultative anaerobe
Non-spore-forming
It belongs to the same family
as Escherichia, which includes the
species E.coli.
7. Cont. …
Predominantly motile
Has peritrichous flagella (flagella
that are all around the cell body)
Presence of fimbriae projections
that aid attachment to the gut.
Ability to survive on diverse carbon
sources.
Ability to synthesize aromatic amino
acids.
8. Cont. …
Refrigeration prevents growth but
does not kill bacteria.
Heating at 57-60°C has shown to be
effective in killing the bacteria.
Optimal growth: 37°C
9. Cont. …
Bacterium of 2501 identified strains, as of 2001.
Many different diseases are caused by more than 1,400
serotypes of this bacteria genus.
10. Cont. …
One major problem of Salmonella is its colonization without
disease, which leads to contamination of meat prior to or at
slaughter.
Caeca are the main sites of colonization, up to 10 log 10 CFU
per gram of fecal material may occur.
Persistence may occur for several months and be
accompanied by fecal shedding.
Transmission through flocks appear due to coprophagic
behavior (coprophagy is the consumption of feces).
11. Plan of Talk
Salmonella overview
Etiology
Transmission
Clinical signs
Post mortem lesions
Treatment
13. Types Of Salmonella Infection In Poultry
1. Colonization of GIT + little or no systemic invasion.
E.g. S. Hadar, S. Infantis
2. Colonization of GIT + transient systemic infection + occasional
vertical transmission
E.g. S. typhimurium, S. Enteritidis
3. Systemic infection + little or no colonization of GIT + vertical
transmission.
E.g. S. Gallinarum, S. Pullorum.
14. Systemic Disease Of Poultry
Specific Serovars
S. Gallinarum
Causes sever systemic disease of all age (fowl typhoid).
Fowl Typhoid has a mortality rate around 60%.
15. Cont. …
S. Pullorum
Causes sever systemic disease in chicks with mortality up to
90%.
Characterized by white diarrhea.
Disease is less sever in older birds.
A carrier state leading to reproductive tract infection may
occur in hens with S. Pullorum leading to vertical
transmission.
16. Plan of Talk
Salmonella overview
Etiology
Transmission
Clinical signs
Post mortem lesions
Treatment
18. Transmission - Horizontal
The bacteria is shed from an infected bird in:
1. Nasal and or ocular secretions.
2. Fecal material.
3. Feather dust.
19. Transmission - Horizontal
The organism remains stable outside the host body and dries as
a dusty substance.
This dust or aerosol contaminates the air that is then
inhaled by another possible host.
Susceptibility as well as the amount of contamination
determine whether or not the new host becomes infected
with the disease.
Transmission may be primarily through the air.
Salmonella spp. are mainly transmitted by the fecal-oral
route.
21. Plan of Talk
Salmonella overview
Etiology
Transmission
Clinical signs
Post mortem lesions
Treatment
22. Clinical Signs
General symptoms of Salmonella include:
1. Lethargy.
2. Anorexia.
3. Diarrhea.
In chronic cases
1. Arthritis may be present.
With high dose infections:
1. Excessive thirst.
2. Conjunctivitis.
3. Indications of liver, spleen, kidney or heart damage can occur.
23. Plan of Talk
Salmonella overview
Etiology
Transmission
Clinical signs
Post mortem lesions
Treatment
24. Post-mortem Lesions
In acute disease there may be few lesions.
1. Dehydration.
2. Enteritis.
3. Focal necrotic intestinal lesions.
4. Foci in liver.
5. Unabsorbed yolk.
6. Cheesy cores in caecae.
7. Pericarditis.
8. Perihepatitis.
9. Misshapen ovules in the ovaries in S.E. infection.
25. Plan of Talk
Salmonella overview
Etiology
Transmission
Clinical signs
Post mortem lesions
Treatment
26. Treatment
Treatment of salmonella infections are more successful if
salmonella species is first determined.
Once the particular species of salmonella has been identified,
the appropriate antibiotic can be administered.
The frequently found Salmonella strains are sensitive to many
commonly available antibiotics.