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Avian Salmonellosis
Disease Overview
Plan of Talk
 Salmonella overview
 Etiology
 Transmission
 Clinical signs
 Post mortem lesions
 Treatment
Plan of Talk
 Salmonella overview
 Etiology
 Transmission
 Clinical signs
 Post mortem lesions
 Treatment
Salmonella Overview
Salmonellosis is any of
several bacterial infections
caused by species of
Salmonella, ranging from
mild to serious infections.
Cont. …
“Salmonella”, the name, derived from Dr.
Daniel Salmon, a U.S. veterinary
surgeon, who discovered and isolated
the strain enterica or choleraesuis from
the intestine of a pig in 1885.
Cont. …
 Rod-shaped
 Gram-negative
 Facultative anaerobe
 Non-spore-forming
 It belongs to the same family
as Escherichia, which includes the
species E.coli.
Cont. …
 Predominantly motile
 Has peritrichous flagella (flagella
that are all around the cell body)
 Presence of fimbriae projections
that aid attachment to the gut.
 Ability to survive on diverse carbon
sources.
 Ability to synthesize aromatic amino
acids.
Cont. …
 Refrigeration prevents growth but
does not kill bacteria.
 Heating at 57-60°C has shown to be
effective in killing the bacteria.
 Optimal growth: 37°C
Cont. …
 Bacterium of 2501 identified strains, as of 2001.
 Many different diseases are caused by more than 1,400
serotypes of this bacteria genus.
Cont. …
 One major problem of Salmonella is its colonization without
disease, which leads to contamination of meat prior to or at
slaughter.
 Caeca are the main sites of colonization, up to 10 log 10 CFU
per gram of fecal material may occur.
 Persistence may occur for several months and be
accompanied by fecal shedding.
 Transmission through flocks appear due to coprophagic
behavior (coprophagy is the consumption of feces).
Plan of Talk
 Salmonella overview
 Etiology
 Transmission
 Clinical signs
 Post mortem lesions
 Treatment
Avian Salmonellosis
Caused by serovars of salmonella enterica.
Types Of Salmonella Infection In Poultry
1. Colonization of GIT + little or no systemic invasion.
E.g. S. Hadar, S. Infantis
2. Colonization of GIT + transient systemic infection + occasional
vertical transmission
E.g. S. typhimurium, S. Enteritidis
3. Systemic infection + little or no colonization of GIT + vertical
transmission.
E.g. S. Gallinarum, S. Pullorum.
Systemic Disease Of Poultry
Specific Serovars
S. Gallinarum
 Causes sever systemic disease of all age (fowl typhoid).
 Fowl Typhoid has a mortality rate around 60%.
Cont. …
S. Pullorum
 Causes sever systemic disease in chicks with mortality up to
90%.
 Characterized by white diarrhea.
 Disease is less sever in older birds.
 A carrier state leading to reproductive tract infection may
occur in hens with S. Pullorum leading to vertical
transmission.
Plan of Talk
 Salmonella overview
 Etiology
 Transmission
 Clinical signs
 Post mortem lesions
 Treatment
Transmission
Salmonella transmission may be;
1. Horizontal
2. Vertical
Transmission - Horizontal
The bacteria is shed from an infected bird in:
1. Nasal and or ocular secretions.
2. Fecal material.
3. Feather dust.
Transmission - Horizontal
The organism remains stable outside the host body and dries as
a dusty substance.
This dust or aerosol contaminates the air that is then
inhaled by another possible host.
Susceptibility as well as the amount of contamination
determine whether or not the new host becomes infected
with the disease.
 Transmission may be primarily through the air.
 Salmonella spp. are mainly transmitted by the fecal-oral
route.
Transmission - Vertical
Occurs in birds, with contamination of the vitelline membrane,
albumen and the yolk of eggs.
Plan of Talk
 Salmonella overview
 Etiology
 Transmission
 Clinical signs
 Post mortem lesions
 Treatment
Clinical Signs
General symptoms of Salmonella include:
1. Lethargy.
2. Anorexia.
3. Diarrhea.
In chronic cases
1. Arthritis may be present.
With high dose infections:
1. Excessive thirst.
2. Conjunctivitis.
3. Indications of liver, spleen, kidney or heart damage can occur.
Plan of Talk
 Salmonella overview
 Etiology
 Transmission
 Clinical signs
 Post mortem lesions
 Treatment
Post-mortem Lesions
In acute disease there may be few lesions.
1. Dehydration.
2. Enteritis.
3. Focal necrotic intestinal lesions.
4. Foci in liver.
5. Unabsorbed yolk.
6. Cheesy cores in caecae.
7. Pericarditis.
8. Perihepatitis.
9. Misshapen ovules in the ovaries in S.E. infection.
Plan of Talk
 Salmonella overview
 Etiology
 Transmission
 Clinical signs
 Post mortem lesions
 Treatment
Treatment
 Treatment of salmonella infections are more successful if
salmonella species is first determined.
 Once the particular species of salmonella has been identified,
the appropriate antibiotic can be administered.
 The frequently found Salmonella strains are sensitive to many
commonly available antibiotics.
Treatment
 Antibiotics
 Antidiarrheal

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Salmonella in poultry_disease overview

  • 2. Plan of Talk  Salmonella overview  Etiology  Transmission  Clinical signs  Post mortem lesions  Treatment
  • 3. Plan of Talk  Salmonella overview  Etiology  Transmission  Clinical signs  Post mortem lesions  Treatment
  • 4. Salmonella Overview Salmonellosis is any of several bacterial infections caused by species of Salmonella, ranging from mild to serious infections.
  • 5. Cont. … “Salmonella”, the name, derived from Dr. Daniel Salmon, a U.S. veterinary surgeon, who discovered and isolated the strain enterica or choleraesuis from the intestine of a pig in 1885.
  • 6. Cont. …  Rod-shaped  Gram-negative  Facultative anaerobe  Non-spore-forming  It belongs to the same family as Escherichia, which includes the species E.coli.
  • 7. Cont. …  Predominantly motile  Has peritrichous flagella (flagella that are all around the cell body)  Presence of fimbriae projections that aid attachment to the gut.  Ability to survive on diverse carbon sources.  Ability to synthesize aromatic amino acids.
  • 8. Cont. …  Refrigeration prevents growth but does not kill bacteria.  Heating at 57-60°C has shown to be effective in killing the bacteria.  Optimal growth: 37°C
  • 9. Cont. …  Bacterium of 2501 identified strains, as of 2001.  Many different diseases are caused by more than 1,400 serotypes of this bacteria genus.
  • 10. Cont. …  One major problem of Salmonella is its colonization without disease, which leads to contamination of meat prior to or at slaughter.  Caeca are the main sites of colonization, up to 10 log 10 CFU per gram of fecal material may occur.  Persistence may occur for several months and be accompanied by fecal shedding.  Transmission through flocks appear due to coprophagic behavior (coprophagy is the consumption of feces).
  • 11. Plan of Talk  Salmonella overview  Etiology  Transmission  Clinical signs  Post mortem lesions  Treatment
  • 12. Avian Salmonellosis Caused by serovars of salmonella enterica.
  • 13. Types Of Salmonella Infection In Poultry 1. Colonization of GIT + little or no systemic invasion. E.g. S. Hadar, S. Infantis 2. Colonization of GIT + transient systemic infection + occasional vertical transmission E.g. S. typhimurium, S. Enteritidis 3. Systemic infection + little or no colonization of GIT + vertical transmission. E.g. S. Gallinarum, S. Pullorum.
  • 14. Systemic Disease Of Poultry Specific Serovars S. Gallinarum  Causes sever systemic disease of all age (fowl typhoid).  Fowl Typhoid has a mortality rate around 60%.
  • 15. Cont. … S. Pullorum  Causes sever systemic disease in chicks with mortality up to 90%.  Characterized by white diarrhea.  Disease is less sever in older birds.  A carrier state leading to reproductive tract infection may occur in hens with S. Pullorum leading to vertical transmission.
  • 16. Plan of Talk  Salmonella overview  Etiology  Transmission  Clinical signs  Post mortem lesions  Treatment
  • 17. Transmission Salmonella transmission may be; 1. Horizontal 2. Vertical
  • 18. Transmission - Horizontal The bacteria is shed from an infected bird in: 1. Nasal and or ocular secretions. 2. Fecal material. 3. Feather dust.
  • 19. Transmission - Horizontal The organism remains stable outside the host body and dries as a dusty substance. This dust or aerosol contaminates the air that is then inhaled by another possible host. Susceptibility as well as the amount of contamination determine whether or not the new host becomes infected with the disease.  Transmission may be primarily through the air.  Salmonella spp. are mainly transmitted by the fecal-oral route.
  • 20. Transmission - Vertical Occurs in birds, with contamination of the vitelline membrane, albumen and the yolk of eggs.
  • 21. Plan of Talk  Salmonella overview  Etiology  Transmission  Clinical signs  Post mortem lesions  Treatment
  • 22. Clinical Signs General symptoms of Salmonella include: 1. Lethargy. 2. Anorexia. 3. Diarrhea. In chronic cases 1. Arthritis may be present. With high dose infections: 1. Excessive thirst. 2. Conjunctivitis. 3. Indications of liver, spleen, kidney or heart damage can occur.
  • 23. Plan of Talk  Salmonella overview  Etiology  Transmission  Clinical signs  Post mortem lesions  Treatment
  • 24. Post-mortem Lesions In acute disease there may be few lesions. 1. Dehydration. 2. Enteritis. 3. Focal necrotic intestinal lesions. 4. Foci in liver. 5. Unabsorbed yolk. 6. Cheesy cores in caecae. 7. Pericarditis. 8. Perihepatitis. 9. Misshapen ovules in the ovaries in S.E. infection.
  • 25. Plan of Talk  Salmonella overview  Etiology  Transmission  Clinical signs  Post mortem lesions  Treatment
  • 26. Treatment  Treatment of salmonella infections are more successful if salmonella species is first determined.  Once the particular species of salmonella has been identified, the appropriate antibiotic can be administered.  The frequently found Salmonella strains are sensitive to many commonly available antibiotics.