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    DIAGNOSTIC AND STATISTICAL
           MANUAL OF
        MENTAL DISORDERS
                                                        FOURTH EDITION

                                                       TEXT REVISION

                                                                                                                            TM
                                                                          -                      -




                                                                               184 4



         _-                     .             .    .   _-_·           -       ----·              -.            .             .

                                                     Published by the
                                              American Psychiatric Association
                                                     Washington, DC

-
'
Copyright© 2000 American Psychiatric Association
DSM, DSM-IV, and DSM-IV-TR are trademarks of the American Psychiatric Association. Use
of these terms is prohibited without permission of the American Psychiatric Association.
ALL RIGHTS RESERVED. Unless authorized in writing by the APA, no part of this book may
be reproduced or used in a manner inconsistent with the AP A's copyright. This prohibition ap-
plies to unauthorized uses or reprod1,1 ctions in any fom1, including electronic applications.
Correspondence regarding copyright permissions should be directed to the DSM Permissions,
Office of Publishing Operations, American Psychiatric Association, 1400 K Street, N.W., Wash-
ington, DC 20005.
Manufactured in the United States of America on acid-free paper.
American Psychiatric Association
1400 K Street, N.N., Washington, DC 20005
www.psych.org
The correct citation for this book is American Psychiatric Association: Diagnostic and Sialisticnl
M.n1mal of Mental Disorders, Fourth Edition, Text Revision. Washington, DC, American Psychi-
atric Association, 2000.
Library of Congress Cataloging-in-Publication Data
Diagnostic and statistical manual of mental disorder5 : OSM-IV.~th ed., text revision.
    p. ; em.
  Prepared by the Task Force on OSM-IV and other committees and work groups of the Amer-
ican Psychiatric Association.
  Includes index.
  IS B1 0-89042-02+6 (casebound: a1k. paper}-ISB1 0-89042-025--! (pbk : alk. paper)
  l. Mental illness-Classification-Handbooks, manuals, etc. 2. Mental illness-Diagnosis-
H andbooks, manuals, etc. I. Title: DSM-IV. IT. American Psycltiatric Association. ill. American
Psychiatric Association. Task Force on DSM-IV.
   [DNLM: 1. Mental Disorders-classification. 2.. Mental Disorders-diagnosis.
VM 15 D536 2000}
RC!55.2..C! D536 2000
616.89'075--dc21
                                                                           00-024852
British Library Cataloguing in Publication Data
A ClP record is available from the British library.
Text Design- Anne Barnes
Manufacturing-R. R. Oonnelley & Sons Company
Contents
                                                                                                     -


Task Force on DSM-IV .. .. ............................. ... xi
Work Groups for the DSM-IV-TR Text Revision ............ .. . xv
Acknowledgments for DSM-IV-TR ..... .... ................ xix
Acknowledgments for
DSM-IV Text Revision ... .. .............. . ............. .. xxi
         .                                                                                     ...
Introd UctiOn   . . . . . . . . . . . ....... . . . . . . . . . . . . . . . . . . . . . . .. XXIII

Cautionary Statement .. .......... .................... xxxvii
Use of the Manual ... .... . ......................... . ..... 1
DSM-IV-TR Classification ................................. 13
Multiaxial Assessment ..................... . ... .. . . . ..... 27
Disorders Usually First Diagnosed in
Infancy, Childhood, or Adolescence . ................ . .... .. 39
Delirium, Dementia, and Amnestic and
Other Cognitive Disorders ...... .... .... .... ............. 135
Mental Disorders Due to a General Medical Condition .. . ..... 181
Substance-Related Disorders .............. , . . ...... .. .... 191

Schizophrenia and
Other Psychotic Disorders . ......... ..... .. .............. 297
Mood Disorders .... .. ............................. .. .. 345
Anxiety Disorders . .. .. ...................... . ..... .. ... 429
Somatoform Disorders ........ . ........... . ....... . .. . . .485
Factitious Disorders ..... ... ......... . .......... .. . . .... 513
Dissociative Disorders .. . ...... ...... ............. ... .... 519
Sexual and Gender Identity Disorders . ...... ..... .. ........ 535
---

      Eating Disorders ............. ..... ......... .......... .. 583
      Sleep Disorders . . ... .......... .. . .. . ................... 597
      Impulse-Control Disorders Not Elsewhere Classified ..... . ... . 663
      Adjustment Disorders ..................... .......... ... 679
      Personality Disorders .......... ............. .. ... . . . . . .. 685
      Other Conditions That May Be a
      Focus of Clinical Attention ...... ............. . .......... 731
      Additional Codes ................... ..... ......... ..... 743

      Appendix A
      Decision Trees for Differential Diagnosis ......... ... ....... 745

      Appendix B
      Criteria Sets and Axes Provided for Further Study .. . ......... 759

      Appendix C
      Glossary of Technica l Terms ....... ... . .............. . ... . 819

      Appendix D
      High lights of Changes in
      DSM-IV Text Revision ................................ ... 829

      Appendix E
      Alphabetical Listing of
      DSM-IV-TR Diagnoses and Codes ......................... 845

      Appendix F
      Numerical Listing of
      DSM-IV-TR Diagnoses and Codes ..... . ...... ........ . . ... 857

      Appendix G
      ICD-9-CM Codes for Selected General Medical
 ·-   Conditions and Medication-Induced Disorders . ............. 867
Appendix H
DSM-IV Classificatio n
(With ICD- 10 Codes) ....................................883           -
Appendix I
Outline for Cultural Formu lation and
Glossary of Culture-Bound Syndr omes ...... .. ... . .. ...... . 897

Appendix J
DSM-IV Contributors ..................... ... . ..... . .. .. 905

Appendix K
DSM-IV Text Revision Advisers .. . .. . . ..................... 929

Index ........ . ........................ .... . . ........ . 933
TASK FORCE ON DSM -IV

                                ALLEN FRANCES, M.D.
                                       Clzairpers011
                            HAROLD ALAN PINCUS, M .D.
                                    Vice-Chairperson
                               MICHAEL B. FIRsT, M .D.
                                 Editor, Text and Criteria
N ancy Coover Andreasen, M.D., Ph.D.              Chester W. Schmidt, M.D.
David H. Barlow, Ph.D.                            Marc Alan Schuckit, M.D.
Magda Campbell, M.D.                              David Shaffer, M.D.
Dennis P. Canhve11, MD.                           Robert L. Spitzer, M.D.
Ellen Frank, Ph.D.                                  Special Adviser
Judith H. Gold, M.D.                              Gary J. Tucker, M.D.
John Gunderson, M.D.                              B. Timothy Walsh, M.D.
Robert E. Hales, M.D.                             Thomas A. Widiger, Ph.D.
Kenneth S. Kendler, M.D.
                                                    Research Coordinator
                                                  Janet B. W. Williams, D.S.W.
David J. Kupfer, M.D.
                                                  Jolm C. Urbaitis, M.D.
Michael R. Liebowitz, M.D.
                                                     Assembly Liaison
Juan Eruique Mezzich, M.D., Ph.D.
                                                  James J. Hudziak, M.D.
Peter E. N athan, Ph.D.                             Reside11t Fellow (199G-1993)
Roger Peele, M.D.                                 Junius Gonzales, M.D.
Darrel A. Regier, M.D., M.P.H.                      Resident Fellow (1988-1990)
A. Jolm.Rush, M.D.

                                     Ruth Ross, M.A.
                                      Scie11ce Editor
                               N ancy E. Vettorello, M.U.P.
                                Administrative Coordinator .._
                             Wendy Wakefield DaYis, Ed.M.
                                   Editorial Coordinator
                                     Cindy D . Jones
                                 Admi11istrntive Assistant
                             N ancy Sydnor-Greenberg, M.A.
                                Administmtive Consultmzt
                                   Myriam Kline, M.S.
                              Focused Field-Trial Coordinator
                           James W. Thompson, M.D., M.P.H.
                             Videotape Field-Trial Coordinator


The DSM-IV Text Reision Work Groups are listed on pp. xv-.wii.

                                              •
                                            XI
••
    XII                                                          DSM-IV Work Groups


                              Anxiety Disorders Work Group
    'Michae l R. Liebowitz, M.D.              James C. Ballenger, M.D.
       Chn irpers011                          Jonathan Davidson, M .D.
    David H. BarlOv, Ph.D.                   Edna Foa, Ph.D.
      Vice· Chn irperson
                                              Abby Fyer, M.D .

                           Delirium, Dementia, and Amnestic and
                           Other Cognitive Disorders Work Group
    Gary J. Tucker, M.D.                      Marshall Folstein, M.D.
       Clmirperson                            Gary Lloyd Gottlieb, M.D.
    Michae l Popkin, M.D.                     Igor Grant, LD.
       Vice-Chnirperso11
                                              Benjamin Liptzin, M.D.
    Eric Douglas Caine, M .D.

                  Disorders Usually First Diagnosed During Infancy,
                      Childhood, or Adolescence Work Group
    David Shaffer, M .D .                     Rachel Klein, Ph.D.
       Co-Cimirpersou                         Benjamin Lahey, Ph.D.
    Magda Campbell, M .D.                     Rolf Loeb e r, Ph.D.
       Co-Cimi1111?TSOII
                                              Jeffrey Newcom, M.D.
    Susan J. Bradley, M .D.
                                              Rhea Paul, Ph.D.
    Dennis P. Cantwell, M.D.
                                              Judith H. L. Rapoport, M .D.
    Gabrielle A. Carls on, M.D.
                                              Sir Michael Rutter, M.D.
    Donald Jay Cohen, M .D.
                                              Fred Volkmar, M.D.
    Barry Garfinkel, M.D.
•                                             JohnS. Werry, M.D .

                               Eating Disorders Work Group
    B. Timotl1y Walsh, M.D.                   Katherine A. Halmi, M.D.
       Clinirperso11                          James Mitchell, lvl.D.
    Paul Garfinkel, M .D.                     G. Terence Wilson, Ph.D.

                               Mood Disorders Work Group
    A. John Rush, M.D.                        David Dunner, M.D.
          Chairperson                         Ellen Frank, Ph.D.
    Martin B. Keller, M.D.                    Donald F. Klein, M.D.
      Vice-Ciwirperso11
     Mark S. Bauer, lvLD.
                      .,
DSM-IV Work Groups                                                                xiii   I
                              Multiaxial Issues Work Group
Janet B. W. Williams, D.S.W.                 Juan Enrique Mezzich, M .D.APh.D :
  Chairperson                                Roger Peele, M.D.
Howard H. Goldman, M.D., Ph.D.               Stephen Setterberg, M.D.
  Vice-Chnirpersoil                          Andrew Edward Skodol IT, M.D.
Alan M. Gruenberg, M.D.

                            Personality Disorders Work Group
Jolm Gunderson, M.D.                         Theodore Millon, Ph .D.
  Chairperson                                Bruce Pfohl, M.D.
Robert M.A. Hirschfeld, M.D.                 Tracie Shea, Ph.D.
  Vice-Clznirperson
                                             Larry Siever, M.D.
Roger Blashfield, Ph.D.
                                             Thomas A. Widiger, Ph.D.
Susan Jean Fiester, M .D.
                      -..
              Premenstrual Dysphoric Disorder Work Group
Judith H. Gold, M.D.                         Sally Severino, MD.
  Chairperson                                N ada Logan Stotland, M.D.
Jean Endicott, Ph.D.                         Ellen Frank, Ph.D.
Barbara Parry, M.D.                             Cons11ltant

              Psychiatric Systems Interface Disorders
     (Adjustment, Dissociative, Factitious, Impulse-Contro l, and
     Somatoform Disorders and Psycholo gica l Factors Affecting
                 Medical Conditions) Work Group
Robert E. Hales, fvLD.                       Steven A. King, M.D.
   Chairperson                               Ronald L. Martin, M.D.
C. Robert Cloninger, M.D.                    Kathaxine Anne Phillips, M.D.
   Vice-Chairperson
                                             David A. Spiegel, M.D.
Jona than F. Borus, M.D.
                                             Alan Stoudemire, M.D.
Jack Denning Burke, Jr., M.D., M.P.H.
                                             James J. Strain, M.D.
Joe P. Fagan, M.D.
                                             Michael G. Wise, MD.

      Schizophrenia and Other Psychotic Disorders Work Group
N ancy Coover Andreasen, M.D., Ph.D.         Samuel Keith, M.D.
   Chairperson                               Kenneth S. Kendler, M.D.
John M. Kane, MD.                            Thomas M cGlashan, M.D.
  V ice-Cizn irperson
•
XIV                                                           DSM-IV Work Groups


                             Sexual Disorders Work Group
Chester W . Schmidt, M.D.                   Leslie Schover, Ph.D.
     Chairperson                           Taylor Seagraves, M .D.
Rau] Schiavi, M.D.                          Thomas N athan W ise, M.D.

                             Sleep Disorders Work Group
David J. Kupfer, M.D.                      Roger Peele, M.D.
     Chairperson                            Quentin Regestein, M.D.
Charles F . Reynolds III, M .D.            Michael Sateia, M.D.
  Vice-Cl111i rperson
                                           Michael Thorpy, M.D .
Daniel Buysse, M.D.

                   Substance-Related Disorders Work Group
Marc Alan Schuckit, M.D .                  Linda B. Cottier, Ph.D.
     Chairperson                            Thomas Crm,.rley, M.D.
John E. Helzer, M.D.                        Peter E. N athan, Ph.D.
     Vice-Chairperson
                                            George E. Woody, M.D.

           Committee on Psychiatric Diagnosis and Assessment
Layton McCurdy, M.D.                        Jerry M. Lewis, M.D.
  Chairperson (1987- 1994)                     Consultant (1988-1994)
Kenneth Z. Altshuler, M .D. (1987-1992)     Daniel J. Luc.hin.s, M.D.
Thomas F. Anders, M.D. (1988-1994)            Consultant (1987-1991)
Susan Jane Blumenthal, M.D. (1990-          Katharine Anne Phillips, M .D.
  1993)                                       Con51tltant (1992- 1994)
Leah Joan Dickstein, M .D. (1988-1991 )     Cynthia Pearl Rose, M .D.
                                              Consultant (1990-1994)
Lewis   J. Judd, M .D. (1988-1994)
                                            Louis Alan Moench, M.D.
Gerald L. Klerman, M .D. (deceased)
                                              Assembly Liaison (1991- 1994)
  (1988-1991)
                                            Steven K. Dobscha, M.D.
Stuart C. Yudofsky, M .D. (1992- 1994)
                                               Resident Fellow (1990-1992)
Jack D. Blaine, M .D.
                                            Mark Zimmerman, M.D .
   Consultant (1987-1992)
                                             Resident Fellow (1992-1994)

               Joint Committee of the Board of Trustees and
                      Assembly of District Branches on
                         Issues Related to DSM-IV
Ronald A. Shello'"' , M.D.                  Leah Joan Dickstein, M .D.
     Chairperson    -.....                  Arthur John Farley, M.D.
Harvey Bluestone, M.D.                      Carol A nn Bernstein, M.D.
1




   WORK GROUPS FOR THE DSM-IV TEXT REVISION

                             J1ICHAEL   B. FIRsT, M .D.
                               Co-Chairperson and Editor
                           H AROLD ALA!J P INCUS, M.D.
                                    Co-Clwirperson
Laurie E. McQueen, M.S.S.'W.                  Yoshie Satake, B.A.
  DSM Project Manager                           DSM Program Coordi11ator

                 Anxiety Disorders Text Revision Work Group
Munay B. Stein, M.D.                         M ichelle Cra.ske, Ph.D.
  Chairperso11                                Edna Foa, Ph.D.
Jonathan Abrammvitz, Ph.D.                    Thomas M ellman, M.D.
Gordon Asmundson, Ph.D.                       Ron N orton, Ph.D.
Jean C. Beckham, Ph.D.                        Franktin Schneier, M.D.
Timothy Brown, Ph.D., Psy.D.                  Richard Zinbarg, Ph.D.

             Delirium, Dementia, and Amnestic and
         Other Cognitive Disorders and Mental Disorders
  Due to a General Medical Condition Text Revision Work Group
Eric Douglas Caine, M.D.                      Jesse Fann, M.D., M.P.H.

         Disorders Usually First Diagnosed During Infancy,
        Childhood, or Adolescence Text Revision Work Group
David Shaffer, M.D.                           Ami Klin, Ph.D.
  Chairperson                                 Daniei Pine, M.D.
Donald J. Cohen, M.D.                         Mark A Riddle, M.D.
Stephen Hinshaw, Ph.D.                        Fred R. Volkmar, M.D.
Rachel G. Klein, Ph.D.                        Charles Zeanah, M.D.
                                                "'
                 Eating Disorders Text Revision Work Group
Katharine L. Loeb, Ph.D.                      B. Timothy Walsh, M.D.

                  Medication-Ind uced Movement Disorders
                        Text Revision Work Group
Gerard Addonizio, M.D.                        Alan Gelenberg, M.D.
Lenard Adler, M.D.                            James Jefferson, M .D.
Burton Angrist, M.D.                          Dilip Jeste, M.D .
Daniel Casey, M.D.                            Peter Weiden, M.D.


                                         XV
Ixvi                                                  DSM-IV-TR Work Groups


                 Mood Disorders Text Revision Work Group
 MarkS. Bauer, M.D.                     Michael E. Thase, M .D.
 Patricia Suppes, M.D., Ph.D.

                     Multiaxial Text Revision Work Group
 Alan M. Gruenberg, M.D.

             Personality Disorders Text Revision Work Group
 Bruce Pfohl, M.D.                      Thomas A Wicliger, Ph.D.

       Premenstrual Dysphoric Disorder Text Revision Work Group
 Sally Severino, M.D.

   Psychiatric System Interface Disorders (Adjustment, Dissociative,
     Factitious, Impulse-Control, and Somatoform Disorders and
         Psychological Factors Affecting Medical Conditions)
                      Text Revision Work Group
 Mitchell Cohen, M.D.                   Russell Noyes, Jr., M.D.
 Marc Feldman, M.D.                     Katharine Anne Phillips. M.D.
 Eric HolJander, M.D.                   Eyal Shemesh, M.D.
 Steven A. King, M.D .                  David A Spiegel, M.D.
 James Levenson, M.D.                   James J. Strain, M.D.
 Ronald L Martin, M.D. (deceased)       Sean H. Yutzy, M.D.
 Jeffrey Iewcom , M.D.

                 Schizophrenia and Other Psychotic Disorders
                         Text Revision Work Group
 Michael Flaum, M.D.                    Xavier Amador, Ph.D.
   Chairperson


   Sexual and Gender Identity Disorders Text Revision W ork Group
 Chester W. Schnudt, M.D.               Thomas Nathan Wise, M.D.
 R. Taylor Segraves, M.D.               Kenneth J. Zucker, Ph.D.

                  Sleep Disorders Text Revision Work Group
 Daniel Buysse, M.D.                    Peter Nowell, M .D.

         Substance-Related Disorders Text Revision Work Group
  Marc Alan Schuckit, M.D .
DSM-IV-TR Work Groups                                                xvii   I
                  American Psychiatric Association
          Committee on Psychiatric Diagnosis and Assessment
David J. Kupfer, M.D.               Louis Alan Moench, M.D.
  Chair                               Assembly Liaison
James Leckman, M.D.                 Jack Barchas, lvLD.
  Member                              Corresponding Member
Katharine Anne Phillips, M.D .      Herbert W. Harris, M.D., Ph.D.
  Member                              Corresponding Member
A. John Rush, M .D.                 Charles Kaelber, M.D.
  Member                              Corresponding Member
Daniel Winstead, M.D.               Jorge A. Cos ta e Silva, M.D.
  Member                              Corresponding Member
Bonnie Zima, M.D., Ph.D.            T. Bedirhan Ustun, M.D.
  Member                               Corresp01zding lviember
Barbara Kennedy, M.D., Ph.D.        Yeshuschandra Dhaibar, M.D.
  Co nsulta11 t                       APA/Glaxo-Wellcome Fellow
Janet B. W. Williams, D .S.W.
  Consultant
Acknowledgments for DSM-IV



D      SM-IV was a team effort. More than 1,000 people (and numerous professional
organizations) have helped us in the preparation of this document. Members of the
Task Force on DSM-IV and DSM-IV Staff are listed on p. xi, members of the DSM-IV
Work Groups are listed on pp. ).:ii-xiv, and a list of other participants is included in
Appendix J.
   The major responsibility for the content of DSM-IV rests with the Task Force on
DSM-N and members of the DSM-IV Work Groups. They have worked (often much
harder than they bargained for) with a dedication and good cheer that has been inspi-
rational to us. Bob Spitzer has our special thanks for his untiring efforts and unique per-
spective. Norman Sartorius, Darrel Regier, Lewis Judd, Fred Good·win, and Chuck
Kaelber were instrumental in facilitating a mutually productive interchange between
the American Psychiatric Association and the World Health Organization that has
improved both DSM-N and ICD-10, and increased their compatibility . We are grate-
ful to Robert Israel, Sue Meads, and Amy Blum at the N ational Center for Health
Statistics and Andrea Albaum-Feinstein at the American Health Infom1ation Man-
agement Association for suggestions on the DSM-IV coding system. Denis Prager,
Peter Nathan, and David KupfeT helped us to develop a novel data reanalysis s trate-
gy that has been supported with funding from the John D. and Catherine T. Mac-
Arthur Foundation.
   Many individuals within the American Psychiatric Association deserve recogni-
tion. Mel Sabshin's special wisdom and grace made even the most tedious tasks seem
worth doing. The American Psychiatric Association Committee on Psychiatric Diag-
nosis and Assessment (chaired by Lay ton McCurdy) provided valuable direction and
cotmsel. We would also like to thank the American Psychiatric Association Presidents
(Drs. Fink, Pardes, Benedek, Hartmann, English, and Mcintyre) and Assembly Speak-
ers (Drs. Cohen, Flamm, Hanin, Pfaehler, and SheUow)....vho helped with the planning
of our w ork Carolyn RobinO·vitz and Jack White, and their respective staffs in the
American Psychiahic Association Medical Director's Office and the Business Admin-
istration Office, have provided valuable assistance in the organization of the project.
   Several other individuals have our special gratitude. Wendy Davis, Nancy Vet-
torello, and Nancy Sydnor-Greenberg developed and implemented an organizational
structure that has kept this complex project from spinning out of control. We have
also been blessed vvith an unusually able administrative s taff, ' "'hich has included
Elisabeth Fitzhugh, t'hl.la Hall, Kelly McKinney, Gloria itliele, Helen Stayna, Sarah
Tilly, N ina Rosenthal, Susan Mann, Joanne M as, and, especially, Cindy Jones. Ruth
Ross, our tireless Science Editor, has been responsible for improving the cla1ity of ex-
pression and organization of DSM-IV. Myriam Kline (Researd1 Coordinator for the
NIH-funded DSM-IV Focused Field TriaJs), Jim Thompson (Research Coordinator for

                                             •
                                           XIX
•




    XX                                                   Acknowledgments for DSM-IV


    the MacArthur Foundation-funded Videotape Field Trial), and Sandy Ferris (Assis-
    tant Director for the Office of Research) have made many valuable contributions. We
    would also like to acknowledge all the other staff persons at the American Psychiatric
    Association who have helped with this project. Ron Mc.MHlen, Claire Reinburg, Pam
    Harley, and Jane Davenport of American Psychiatric Press h ave provided expert pro-
    duction assistance.

    Allen Frances, M.D.
    Cllairpersoll, Task Force 011 DSM-IV
    Harold Alan Pincus, M.D.
    Vice-Chairperson, Task Force 011 DSM-TV
    Michael B. First_ M.D.
    Editor, DSlvf-W Text nud Criteria
    TI·10mas A. Widiger, Ph.D.
    Research Coordinator
Acknowledgments for
    DSM-IV Text Revision



    The      effort to revise the DSM-N text was also a team effort. We are especially in-
    debted to the tireless efforts of the DSM-N Text Revision Work Groups (listed on
    pp. X'V- xvii), who did the lion's share of the work in the preparation of this revision.
    We w ouJd also like to acknm·vledge the contribution of the various advisers to the
    Work Groups (see Appendix K, p . 929), w ho provided their perspective on w hether
    the proposed changes were justified. Finally, we wouJd like to thank the American
    Psychiatric Association's Committee on Psychia h;c Diagnosis and Assessment (listed
    on p . xvii), wh o provided helpful guidance and oversight during the p rocess as ·well
    as approval of the final document. Special gratitude goes to committee members
    Katharine A. Phillips and Janet B. W. Williams, for their meticulously carefuJ review
    of the text revision. OJ course, none of Ulis could have happened without the invalu-
    able organizational and administrative assistance provided by the DSM-IV staff,
    1.-aurie McQueen and Yoshie Satake, and production assistance provided by Anne
    Barnes, Pam Harley, Greg Kuny, Claire Reinbmg, and Ron McMillen at Amer ican
    Psychiatric Press.

    Michael B. First, M.D.
    Co-Cimirperson n11d Editor
    Harold Alan Pincus, M.D.
    Co-Clznirpersou




                                                  •
                                              XXI


•
Introduction



      his is the fourth edition of the American Psychiatric Association's Diagnostic and
Statistical Mmwal of Mental Disorders, or DS1vl-IV. The utility and credibility of DSM-IV
require that it focus on its dinical, reseru·ch, and edu cational purposes and be support·
ed by an extensive empirical foundation. Our highest priority has been to provide a
helpful guide to clinical practice. We h oped to make DSM-IV p ractical and useful for
clinician s by striving for brevity of criteria sets, clarity of language, and explicit state-
ments of the constructs ernbodjed in the diagnostic criteria. An additional goal was to
facilitate research and improve communication among clinicians and researchers. We
were also mindful of the use of DSM-IV for improving the collection of clinical infor-
mation and as an educational tool for teaching p sychopathology.
    An official nomenclature must be applicable in a wide diversity of contexts. DSM-IV
is used by clinicians and researchers of many different orientations (e.g., biological,
psychod)marnic, cognitive, behavioral, interpersonal, family/ systems). It is used by
psychiatrists, other physicians, psychologists, social workers, nurses, occupational and
rehabilitation therapists, counselors, and other h ealth and mental health profession-
als. DSM-IV mus t be usable across settings-inpatient, outpatient, partial hospital,
consultation-liaison, clinic, private practice, and primary care, and with community
populations. It is also a necessary tool for collecting and commwucating accurate
public health s tatistics. Fortunately, all these m any uses are compatible with one
another.
                                                                      n,
    DSM-lV was the product of 13 Work Groups (see Appendix each of which had
primary responsibility for a section of the manual Tllis organization was designed to
increase participation by experts in each of the respective fields. We took a number of
precautions to ensure that the vVork Group recommendations would reflect the
breadth of available evidence and opinion and n ot just the views of the specific mem-
bers. After e-xtensive consultations with experts and clliticians in eacl1 field, we select-
ed Work Group members who represented a wide range of perspectives and
experiences. -fork Group members were instructed that they were to participate as
consensus scholars and not as advocates of previously held vie~ws . Furthermore, we
established a formal evidence-based process for the Work Groups to fo11ow.
    The Work Groups reported to the Task Force on DSM-IV (see p. xi), which consist-
ed of 27 members, many of vhom also cl1aired a Work Group. Each of the 13 vVork
Groups was composed of 5 (or more) members whose reviews were critiqued by
between 50 and 100 advisers, who vvere also cl10sen to represent diverse clinical and
research expertise, disciplines, backgrounds, and settings. The involvement of many
international experts ensured that DSM-JV had ava.i lable the widest pool of informa-
 tion and would be applicable across cultures. Conferences and workshops were held
 to provide conceptual and methodological guidance for the DSM-IV effort. These

                                             -··
                                           XXIII
I
xxiv                                                                            Introduction


included a number of consultations between the developers of DSM-IV and the de-
velopers of ICD-10 conducted for the purpose of increasing compatibility between
the two systems. Also held were methods conferences that focused on culrural factors
in the diagnosis of mental disorder, on geriatric diagnosis, and on psychiatric diag-
nos is in primary care settings.
   To maintain open and extensive lines of communication, the Task Force on DSM-IV
established a liaison with many other components within the American Psycluatric
Association and with more than 60 organizations and associations interested in the
development of DSM-IV (e.g., American Health Information Management Associa-
tion, American Nurses' Association, Am.erican Occupational Therapy Association,
American Psychoanalytic Association, American Psychological Association, Ameri-
can Psychological Society, Coalition for the Family, Group for the Advancement of
Psycl1iatry, N ational Association of Social Workers, National Center for H ealth Sta-
tistics, World Health Organization ). We attempted to air issues and empirical evi-
dence early in the process in order to identify potential problems and differences in
interpretation. Excl1anges of information were also made poss ible through the distri-
bution of a semiannual n ewsletter (the DSM-IV Update), the publication of a regular
column on DSM-IV in Hospital a11d ConummihJ PSljchiatn;, frequent presentations at
national and intemational conferences, and numerous journal articles.
    Two years before the publication of DSM-IV, the Tas k Force published and wi dely
distributed the DSM-W Oplious Book. This volume presented a comprehensive sum-
mary of the alternative proposals that were being considered for inclusion in DSM-IV
in order to solicit opinion and additional data for our deliberations. W e received ex-
te ns ive correspondence from interested individuals who shared v.rith us additional
data and recommendations on the potential impact of the possible changes in DSM-fV
on their clinical practice, teaching, research, and administrative work. Tlus breadth of
discussion helped us to anticipate problems and to attempt to find the best solution
among the various options. One year before the publication of DSNf-IV, a near-final
draft of the proposed criteria sets was distributed to allow for one last critique.
    In arriving at final DSM-IV decisions, the Work Groups and the Task Force re-
viewed all of the extensive empirical evidence and correspondence that had been
gathered. It is our belief that the major innovation ofDSM-IV lies not in any of its spe-
cific content changes but rather in the systematic and explicit process b y wlucl1. it was
constructed and documented. More than any oth er nomenclature of mental disor-
ders, DSM-IV is grounded in empirical evidence.


                              Historical Background
    The need for a classification of mental disorders has been clear throughout the history
    of medicine, but there has been little agreement on which disorders should be includ-
    ed and the optimal method for their organization. The many nomenclahlres that have
    been developed during the past hvo millennia have differed in their relative empha-
    sis on phenomenology, etiology, and course as defining features. Some systems h ave
    included only a handful of diagnostic categories; o thers have included thousands.
    Moreover, the various systems for categorizin g mental disorders have differed with
    respect to whether their principle objective vas for use in clinical, research, or statis-
    tical settings. Because the history of classification is too extensive to be summarized
Introduction                                                                          .xxix     I
fourth volume contains reports of the data reanalyses, reports of the field trials, and
a final executive summary of the rationale for the decisions made by each. Work
Group. Tn addition, many papers were stimulated by the efforts toward empirical
d ocumentation in DSM-N, and these have been published in peer-reriewed journals.


                              Relation to ICD-10
Tile tenth revision of the l11tematio11al Statistical Classiftcntioll of Diseases and Related
Health Problems (ICD-10), developed by WHO, was published in 1992. A clinical mod-
ification of ICD-10 (ICD-10-CM) is expected to be implemented in the United States
in 2004. Those preparing [CO-l 0 and DSM-IV have worked closely to coordinate their
efforts, res ulting in much mutual influence. ICD-10 consists of an official coding sys-
tem and other related clinical and research documents and ins truments. The codes
and terms provided in DSM-N are fully compatible w ith both ICD-9-CM and ICD-10
(see Appendix H). The clinical and research drafts of ICD-10 were thoroughly re-
v iewed by the DSNf-N Work Groups and suggested important topics for DSM-IV lit-
erature reviews and data reanalyses. Draft versions of the ICD-10 Diagnostic Criteria
for Research were included as alternatives to be compared with DSM-ID, DSM-ill-R,
and suggested DSM-IV criteria sets in the DSM-IV field trials. The many consul-
tations behveen the developers of DSM-IV and ICD-10 (which were facilitated by
NIMH, NIDA, and NIAAA) were enormously useful in increasing the congruence
and reducing meaningless differences in wording between the hvo systems.


                       The DSM-IV Text Revision
One of the m ost important uses of DSM-IV has been as an educational tool. This is
especially true of the descriptive text that accompanies the criteria sets for DSM-IV
disorders. Given that the interval beh'een DSM-IV and DSM-V is being extended
relative to the intervals behveen earlier editions (from 7 years beh,•een DSM-ill and
DSM-ill-R and behveen DSM-ill-R and DSM-IV, to at least 12 years), the infom1ation
in the text (which was prepared on the basis of literature dating up to 1992) runs the
risk of becoming inueasingly out-of-pace -.. -.rith the large volume of research pub-
lis hed ead'l year. In order to bridge the span between DSM-IV and DSM-V, a revision
of the DSM-IV text was undertaken. The goals of this text revision were severalfold:
1) to correct any factual errors that were identified in the DSM-IV text; 2) to review
the DSM-IV text to ensure that all of the information is still up-to-date; 3) to make
changes to the DSM-IV text to reflect new information a·ailable since the DSM-IV lit-
erature reviews ·were completed in 1992; 4) to make improve:men ts that will enhance
the educational v alue of DSM-IV; and 5) to update those ICD-9-CM codes that were
changed since the DSM-IV 1996 Coding Update. As with the original DSM-IV, all
changes proposed for the text had to be supported by empirical data. Furthermore,
all proposed changes 'vere limited to the text sections (e.g., Associated Features and
Disorders, Prevalence). No s ubs tantive changes in the criteria sets were considered,
nor were any proposals entertained for new disorders, new s ubtypes, or changes in
the statu s of the DSM-IV appendix categories.
    The text revision process began in 1997 with the appoinbnent of DSM-IV Text Re-
vision Work Groups, correspon ding to the original DSM-IV Work Group structure.
Introduction                                                                          XXV      I
here, v,re focus briefly only on those aspects that have led directly to the development
of the Diagnostic and Statistical Manual of Me11tal Disorders (DSM) and to the "Mental
Disorders" sections in the various editions of the International Classification of Diseases
(ICD).
   In the United States, the initial impetus for developing a classification of mental
disorders ·w as the need to collect statistical infom1ati.on. What might be considered
the first official attempt to gather infom1ation about mental illness in the United
States was the recording of the frequency of one category- "idiocy/ insanity" in the
1840 census. By the 1880 census, seven categories of mental illness w ere distin-
guished- mania, melancholia, monomania, paresis, dementia, dipsomania, and epi-
lepsy. In 1917, the Committee on Statistics of the American Psychiatric Association
(at that time called the American Medico-Psychological Association [the name was
changed in 1921]), together with the National Commission on Mental H ygiene, for-
mulated a plan that was adopted by the Bureau of the Censu s for gathering wliform
statistics across mental hospitals. Although this system devoted more attention to
clinical utility than did previous systems, it was still primarily a statistical classifica-
tion. The American Psychiatric Association subsequently collaborated with the New
York Academy of Medicine to develop a nationally acceptable psychiatric nomen-
clature that vould be incorporated within the first edition of the American Medical
Association's Standard Classified Nomenclature of Disease. This nomenclature was
designed primarily for diagnosing inpatients w ith severe psychiatric and neurologi-
cal d isorders.
   A much broader nomenclature was later developed by the U.S. Army (and modi-
fied b y the Veterans Administration) in order to better incorporate the outpatient pre-
sentations of World War II servicemen and veterans (e.g., psychophysiological,
personality, and acute disorders). Contemporaneously, the World Health Organi-
zation (WHO) published the sixth edition of ICD, which, for the first time, included
a section for mental disorders. ICD-6 ·was heavily influenced by the Veterans Admin-
istration nomenclature and included 10 categories for psychoses, 9 for psychoneuro-
ses, and 7 for disorders of character, behavior, and inteljjgence.
   The American Psychiatric Association Committee on -omenclature and Statistics
developed a variant of the ICD-6 that was published in 1952 as the first edition of the
Ding11ostic a11d Statistical Manual: Mental Disorders (DSM-I). DSM-I contained a glossa-
ry of descriptions of the diagnostic categories and w'as the first official manual of
mental disorders to focus on clinical utility. The use of the term reaction throughout
DSM-1 reflected the influence of Adolf Meyer's psychobiological view that mental
disorders represented reactions of the personality to psychological, social, and bio-
logical factors.
   In part because of the lack of · idespread acceptance of the mental disorder taxon-
                                   w
omy contained in ICD-6 and ICD-7, WHO sponsored a comprehensive review of
diagnostic issues that was conducted by the British psychiahist StengeL His report
can be credited with having inspired many of the recent advances in diagnostic meth-
odology- most especially the need for ex-plicit definitions as a means of promoting
reliable clinical diagnoses. However, the next round of diagnostic revision, whid1led
to DSM-ll and ICD-8, did not follow Stengel's recommendations to any great degree.
DSM-ll v.ras similar to DSM-I but eliminated the term t·eaction.
   As had been the case for DSM-I and DSM-IT, the development of DSlvl-III was co-
I
xxvi                                                                          Introdu ction


ordinated with the development of the next (ninth) version of ICD, which was pub-
lished in 1975 and implemented in 1978. Work began on DSM-III in 1974, with
publication in 1980. DSM-III introduced a number of important methodological inno-
vations, including explicit diagnostic criteria, a multiaxial system, and a descriptive
approach that attempted to be neutral with respect to theories of etiology. This effort
was facilitated by the extensive empirical v.rork then under way on the construction
and validation of explicit diagnostic criteria and the development of semistructured
inten~iews. ICD-9 did not include diagnostic criteria or a multiaxial system largely
because the primary function of this intemational system was to delineate categories
to facilitate the collection of basic health statistics. In contrast, DSlvl-III was developed
with the additional goal of providing a medical nomenclature for clinicians andre-
seardlers. Because of dissatisfaction across all of medicine with the lack of specificity
in ICD-9, a decision was made to modify it for use in the United States, resulting in
ICD-9-CM (for Clinical Modification).
   Experience with DSM-ill revealed a number of inconsistencies in the system and a
number of instances in which the criteria were not entirely clear. Therefore, the Amer-
ican Psychiatric Association appointed a Work Group to Revise DSM-III, which de-
veloped the revisions and corrections that led to the publication of DSM-III-R in 1987.


                    The DSM-IV Revision Process
The third edition of the Diagnostic and Stntisticallvimwal of Mental Disorders (DSM-III)
represented a major advance in the diagnosis of mental disorders and greatly faci1i-
tated empirical research. The development of DSM-IV has benefited from the s ub-
stantial increase in the research on diagnosis that was generated in part by DSM-III
and DSM-III-R. Most diagnoses now have an empirical literature or available data
sets that are relevant to decisions regarding the revision of the diagnostic manual.
The Task Force on DSM-IV and its Work Groups conducted a three-stage empirical
process that included 1) comprehensive and systematic reviews of the published lit-
erature, 2) reanalyses of already-collected data sets, and 3) extensive issue-focused
field tria Is.


    Literature Reviews
Two methods conferences were sponsored to articulate for all the Work Groups a sys-
tematic procedure for finding, extracting, aggregating, and interpreting data in a
comprehensive and objective fashion. The initial tasks of each of the DSM-IV Work
Groups were to identify the most pertinent issues regarding each diagnosis and to de-
termine the kinds of empirical data relevant to their resolution. A Work Group mem-
ber or adviser was then assigned the responsibility of conducting a systematic and
comprehensive review of tl1e relevant literature that would inform the resolution of
the issue and also document the text of DSM-IV. The domains considered in making
decisions included clinical utility, reliability, descriptive validity, psychometric per-
 formance characteristics of individual criteria, and a number of validating variables.
    Eadlliterature review specified 1) the issues or aspects of the text and criteria un-
 der consideration and the significance of the issues '"~th respect to DSM-IV; 2) there-
 view method (including the sources for identifying rele,·ant studies, the number of
Introd uction                                                                     xxvii 

studies considered, the criteria for inclu sion and exclusion from the review, and the
variables catalogued in each study); 3) the results of the review (including a descrip-
tive summary of the studies with respect to methodology, design, and substantive
correlates of the findings, the relevant findings, and the analyses conducted on these
findings); and 4) the various options for resolving the issue, the advantages and dis-
advantages of each option, recommendations, and suggestions for additional re-
search that would be needed to provide a more concJusive resolution.
   The goal of the DSM-IV literature reviews was to provide comprehensive and un-
biased information and to ensure that DSM-IV reflects the best available cJinical and
research literature. For this reason, we used systematic computer searches and critical
reviews done by large groups of advisers to ensure Hlat the literahue coverage -vas
adequate and that the interpretation of the results was justified. Input was solicited
especially from those persons likely to be critical of the conclusions of the review. ll1e
literature reviews were revised many times to produce as comprehensive and bal-
anced a result as possible. It must be noted that for some issues addressed by the
DSM-IV Work Groups, particularly those that were more conceptual in nature or for
which there were insufficient data, a review of the empirical literature had limited
utility. Despite these limitations, the reviews were helpful in documenting the ratio-
nale and empirical support for decisions made by the DS!vf-IV Work Groups.


Data Reanalyses
When a review of the literature revealed a lack of evidence (or conflicting evidence)
for the resolution of an issue, we often made use of two additional resources-data
reanalyses and field trials-to help in making final decisions. Analyses of relevant
unpublished data sets were supported b y a grant to the American Psychiatric Asso-
ciation from the John D. and Catherine T. MacArthur foundation. Most of the -!0 data
reanalyses performed for DSM-IV involved the collaboration of several investigators
at different sites. These researchers jointly subjected their data to questions posed by
the Work Groups concerning the criteria included in DSM-ill-R or criteria that might
be included in DSM-IV. Data reanalyses also made i t possible for Work Groups
to generate several criteria sets that were then tested in the DSM-IV field trials. Al-
though, for the most part, the data sets used in the reanalyses had been coJJected as
part of epidemiological studies or treatment or other clinical studies, they were also
highly relevant to the nosological questions facing the DSM-IV Work Groups.


Field Trials
Twelve DSM-IV field trials were sponsored by the National Institute of Mental
Health (NThtlli) in collaboration with the Nationallnstitute on Drug Abuse ( ITDA)
and the National Institute on Alcohol Abuse and Alcoholism {NIAAA). The field tri-
als allowed the DSM-IV Work Groups to compare altemative options and to study
the possible impact of suggested changes. Field trials compared DSM-III, DSM-III-R,
ICD-10, and proposed DSM-IV criteria sets in 5-10 different sites per field trial, v.•ith
approximately 100 subjects at each site. Diverse sites, with representative groups of
subjects from a range of socioculhual and ethnic backgrounds, ·w ere selected to en-
snre generaJizability of field-trial results and to test some of the most difficult ques-
I xxviii                                                                       Introduction


 tions in differential ctiagnosis. The 12 field trials included more than 70 sites and
 evaluated more than 6,000 subjects. The field trials collected information on the reli-
 ability and performance cl1aracteristics of each criteria set as a whole, as ~well as of the
 specific items within each criteria set. The field trials also helped to bridge the bound-
 ary between clinical researcl1 and clinical practice by determining how well sugges-
 tions for change that are derived from clinical research findings apply in clinical
 practice.


 Criteria for Change
 Although it 1vas impossible to develop absolute and infallible criteria for when cl1anges
 should be made, there were some principles that guided om efforts. The threshold for
 making revisions in DSM-IV was set higher than that for DSM-ffi and DSM-ill-R. Deci-
 sions had to be substantiated by explicit statements of rationale and by the systematic re-
 view of relevant empirical data. To increase the practicality and clinical utility of DSM-IV,
 the criteria sets were simplified and clarified when this could be justified by empirical
 data. An attempt was made to strike an optimal balance in DSM-IV with respect to his-
 torical tradition (as embodied in DSM-ill and DSM-ID-R), compatibility with ICD-10,
 evidence from rev iews of the literature, analyses of unpublished data sets, results of field
 trials, and consensus of the field . Although the amount of evidence required to support
 changes >vas set at a high thresho1d, it necessarily varied across disorders because the
 empirical support for the decisions made in DSM-ID and DSM-ID-R also varied across
 disorders. Of comse, common sense was necessary, and major changes to solve minor
 problems required more evidence than minor changes to solve major problems.
    We received suggestions to include numerous new diagnoses in DSM-IV. The pro-
 ponents argued that the new diagnoses were necessary to improve the coverage of the
 system by including a group of individuals that vere undiagnosable in DSM-ill-R or
 diagnosable only under the . Jot Otherwise Specified rubric. We decided that, in
 general, n ew diagnoses should be included in the system only after research has es-
 tablished that they should be included rather than being included to s timulate that
 researcl1. However, diagnoses already included in ICD-10 were given somewhat
 more consideration than those that were being proposed fresh for DSM-IV. The in-
 creased marginal utility, clarity, and coveTage provided by each newly proposed di-
 agnosis had to be balanced against the cumulative cumbersomeness imposed on the
 'vhole system, the paucity of en1pirical documentation, and the possible misdiagnosis
 or misuse that might result. No classification of mental disorders can have a sufficient
 number of specific categories to encompass every conceivable clinical presentation.
 The -ot Otherwise Specified categories are provided to cover the not infrequent pre-
 sentations that are at the boundary of specific categorical definitions.


 The DSM-/V Sourcebook
 Documentation has been the e...c:sential foundation of the DSM-IV process. The DSM-N
 Sourcebook, published in four volumes, is intended to provide a comprehensive and
 convenient reference record of the clinical and researd1 support for the v arious deci-
 sions reached by the Work Groups and the Task Force. The first three volumes of the
 Sourcebook contain condensed versions of the 150 DSM-IV literature reviews. The
lxxx                                                                        Introduction


The chairs of the original DSM-IV Work Groups were consulted first regarding the
composition of these Text Revision Work Groups. Each Text Revision Work Group
was given primary responsibility for updating a section of the DSM-IV text. This en-
tailed reviewing the text carefully to identify errors or omissions and then conducting
a systematic, comprehensive literature review that focused on relevant material that
has been published since 1992. Text Revision Work Group members then drafted pro-
posed changes, which w ere accompanied by written justifications for the changes
alon g with relevant references. During a series of conference caUs, the proposed
changes, justifications, and references ·were presented by a Text Revision Work
Group member to other members of the Text Revision Work Group, who provided
input regarding whether the changes were justified on the basis of the supporting
documentation. Once c.i?a.fts of the proposed changes were finalized by the Text Re-
vision Work Groups, the changes were more widely disseminated to a group of sec-
tion-specific advisers (consisting of the original DSM-IV Work Group members
supplemented by additional consultants) for further comment and review. These ad-
visers were also given the opporhmity to suggest additional changes if they could
provide sufficient convincing evidence justifying inclusion in the text. After consid-
eration of the adviser comments, final drafts of proposed changes were produced and
submitted for final review and approval by the American Psychiatric Association's
Committee on Psychiatric Diagnosis and Assessment.
   Most of the proposed literature-based changes were in the Associated Features
and Disorders (which includes Associated Laboratory Findings); Specific Culhue,
Age, and Gender Features; Prevalence; Course; and Familial Pattern sections of the
text. For a number of disorders, the Differential Diagnosis section also was expanded
to provide more comprehensive differentials. Appen dix D (seep. 829) provides an
overview of the changes included in this text revision.


                    Definition of Mental Disorder
 Although this volume is titled the Diag11ostic and Statistical Mmmal of Mental Disorders,
 the term mental disorder unfortunately implies a distinction between "mental" dis-
 orders and "physical" disorders that is a reduction:istic anachronism of mind / body
 dualism. A compelling literahll'e documents that there is much "ph ysical" in "men-
 tal" disorders and much "menta l" in "physical" disorders. TI1e problem raised by the
 term "mental" disorders has been much clearer than its solution, and, unfortunately,
 the term persists in the title of DSM-IV because we have not found an appropriate
 substitute.
     Moreover, although this manual provides a classification of mental disorders, it
 must be admitted that no definition adequately specifi.es precise boundaries for the
 concept of "me11tal disorder." The concept of m ental disorder, like many other con-
 cepts in medicine and science, lacks a consistent operational definition that covers all
 situations. All medical conditions are defined on various levels of abstraction- for
 example, stn1chll'al pathology (e.g., ulcerative colitis), symptom presentation (e.g.,
 migraine), deviance from a physiological norm (e.g., hypertension), and etiology
  (e.g., pneumococcal pnemnonia). Mental disorders have also been defined by a vari-
  ety of concepts (e.g., distress, dysfunction, dyscontrol, disadvantage, disability, in-
  flexibility, irrationality, syndromal pattern, etiology, and statistical deviation). Each
Introduction                                                                       xxxi 

is a useful indicator for a mental disorder, but none is equivalent to the concept, and
dillerent situations caJJ for dillerent definitions.
    Despite these caveats, the definition of mental disorder that was included in OSM-m
and OSM-lll-R is presented here because it is as useful as any other available defini-
tion and has helped to guide decisions regarding which conditions on the boundary
between normality and pathology s hould be included in DSM-IV. In DSM-IV, each of
the mental disorders is conceptualized as a clinically significant behavioral or psy-
chological syndrome or pattern that occurs in an individual and that is associated
v.rith present distress (e.g., a painful symptom) or disability (i.e., ilnpaim1ent in one
or more ilnportant areas of functioning) or with a significantly increased risk of suf-
fering death, pain, disability, or an important loss of freedom. In addition, this syn-
drome or pattern must not be merely an expectable and culturally sanctioned
response to a particular event, for example, the d eath of a loved one. Vvhatever its
original cause, it must currently be considered a manifestation of a behavioral, psycho-
logical, or biological dysfunction in the individual. Neither deviant behavior (e.g., po-
litical, religious, or sexual) nor conflicts that are primarily between the individual and
sodety are mental disorders unless the deviance or conflict is a symptom of a dysfunc-
tion in the indh·i dual, as described above.
    A common misconception is that a classification of mental disorders classifies peo-
ple, when actually what are being classified are disorders that people have. For this
reason, the text of DSM-IV (as did the text of DSM-ill-R) avoids the use of such ex-
pressions as "a schizophrenic" or "an alcoholic" and instead uses the more accurate,
but admittedly more cumbersome, "an individual with Schizophrenia" or "an indi-
vidual with Alcohol Dependence."


                     Issues in the Use of DSM-IV

Limit ations of t he Categorica l Appro ach
DSM-N is a categorical classification that dirides mental disorders into types based
on criteria sets with defining features. This naming of categories is the traditional
method of organizing and transmitting information in ezeryday life and has been the
fundamental approacl1 used mall systems of medical diagnosis. A categorical ap-
proach to classification works best w hen all members of a diagnostic class are homo-
geneous, when there are clear boundaries between classes, and when the different
classes are mutually exclusive. Nonetheless, the limitations of the categorical classifi-
cation system must be recognized.
   ln DSM-IV, there is no assumption that each category of mental disorder is a com-
pletely discrete entity with absolute boundaries dividing it from other mental dis-
orders or from no mental disorder. There is also no assumption that all individuals
desoibedas having the same mental disorder are alike in all important ways. The cli-
nician using DSlvl-lV should therefore consider that mdividuals sharing a diagnosis
are likely to be heterogeneous even in regard to the defining features of the diagnosis
and that boundary cases will be difficult to diagnose in any but a probabilistic fash-
ion. This outlook allows greater flexibility in the use of the system, encourages more
specific attention to boundary cases, and emphasizes the need to capture additional
I
xxxii                                                                        Introd uction

clinical information that goes beyond ctiagnosis. In recognition of the heterogeneity
of clinical presentations, DSM-IV often includes polythetic criteria sets, in which the
individual need only present with a subset of items from a longer list (e.g., the diag-
nosis of Borderline Personality Disorder requires only five out of nine items).
   It was suggested that the DSM-lV Classification be organized following a dimen-
sional model rather than the categorical model used in DSM-TTI-R. A dimensional sys-
tem classifies clinical presentations based on quantification of attributes rather than
the assignment to categories and VOrks best in describing phenomena that are dis-
tributed continuously and that do not have clear boundaries. Although dimensional
systems increase reliability and communicate more clinical information (because they
report clinicalattrip~tes that might be subthreshold in a categorical system), they also
have serious limitations and thus far have been less usefuJ than categorical systems
in clinical practice and in stimulating researd1. Numerical dimensional descriptions
are much less familiar and vivid than are the categorical names for menta] disorders.
Moreover, there is as yet no agreement on the choice of the optimal dimensions to be
used for classification purposes. Nonetheless, it is possible that the increasing re-
search on, and familiarity with, dimensional systems may eventually result in their
greater acceptance both as a method of conveying clinical information and as are-
search tool.


    Use of Clinical Judgment
DSM-JV is a classification of mental disorders that was developed for use in clinical,
educational, and research settings. The diagnostic categories, oiteria, and textual de-
scriptions are meant to be employed by individuals with appropriate clinical training
and experience in diagnosis. It is important that DSM-JV not be applied mechanically
by untrained individuals. The specific diagnostic criteria included in DSM-IV are
mea11t to serve as guidelines to be informed by clinical judgment and are not meant
to be used in a cookbook fashion. For example, the exercise of clinical judgment may
justify giving a certain diagnosis to an individual even though the clinical presenta-
tion falls just short of meeting the full criteria for the diagnosis as long as the symp-
toms that are present are persistent and severe. On the other hand, Jack of familiarity
with DSM-IV or excessively flexible and idiosyncratic applkation of DSM-IV criteria
or conventions substantially reduces its utility as a common language for communi-
cation.
    Ln addition to the need for clinical training and judgment, the method of data col-
lection is also important. The valid application of the diagnostic criteria included in
this manual necessitates an evaluation that directly accesses the information con-
 tained in the criteria sets (e.g., whether a syndrome has persisted for a minimum pe-
 riod of time). Assessments that rely solely on psychological testing not covering the
criteria content (e.g., projective testing) cannot be validly used as the primary source
of diagnostic infom1ation.


    Use of DSM-IV in Forensic Settings
    When the DSM-IV categories, criteria, and textual descriptions are employed for
    forensic purposes, there are significant risks that diagnostic information will be rnis-
•



Introduction                                                                      xxxiii      I
used or misunderstood. These dangers arise because of the imperfect fit between the
questions of ultimate concern to the law and the information contained in a clinical
diagnosis. In most situations, the clinical diagnosis of a DSM-IV mental disorder is
not sufficient to establish the existence for legal purposes of a "mental disorder/'
"mental disability," "m ental disease," or "mental defect ." In determining whether an
individual meets a specified legal standard (e.g., for competen ce, criminal resp onsi-
bility, or disability), additional information is usually required beyond that contained
in the DSM-lV d iagnosis. This m ight include information about the individual's func-
tional impairments and h ow these impairments affect the particular abil ities in ques-
tion. Itis precisely because impairments, abilities, and disabilities vary widely within
each diagnostic category that assignment of a particular diagnosis does not imply a
specific level of impairment or disability.
    Nonclinical decision makers should also be cautioned that a diagnosis d oes not
carry any n ecessary implications regarding the causes of t he individual's mental dis-
order or its associated impaim1ents.lnclusion of a disorder in the Classification (as in
medicine generally) does not require that there be knowledge about its etiology.
Moreover, the fact that an individual's p resentation meets the criteria for a DSM-IV
diagnosis does not carry any necessary implication regard ing the individual's degree
of control over the behaviors that may be associated with the disorder. Even when di-
minished control over one's behavior is a feature of the disorder, having the diagnosis
in itself does not demonstrate tha t a particular individual is (or was) unable to control
his or her behavior at a particular time.
    Tt must be noted that DSM-lV reflects a consensus about the classification and di-
agnosis of mental disorders derived at the time of its initial p ublication. New knowl-
edge generated by research or clinical exrperience will undoubtedly lead to an
increased understanding of the disorders included in DSM-IV, to the identification of
new disorders, and to the removal of some disorders in future classifications. The text
and criteria sets included in DSM-IV will require reconsideration in light of evolving
new infom1ation.
    The u se of DSM-IV in forensic settings should be informed by an awareness of the
 risks and limitations discussed above. When used appropriately, diagnoses and diag-
 nostic information can assist decision makers in their d eterminations. For example,
 when the presence of a m ental disor der is ·the predicate for a s ubsequent legal d eter-
mination (e.g., involuntary civil commitment), the use of--an-established system of
 diagnosis enhances the value and reliability of the determination . By providing a com-
 pendium based on a review of the pertinent clinical and research litera ture, DSM-IV
 may fadlita te the legal decision makers' understanding of the relevant characteristics
 of mental disorders. The literature related to diagnoses also serves as a check on un-
 grounded speculation about mental disorders and about the functioning of a partic-
 ular individual. Finally, diagnostic information regarding longitudinal course may
 improve decis ion making when the legal issue concerns an individual's mental func-
 tioning at a p ast or future point in time.


Ethnic and Cultural Considerations
Special efforts have been made in the preparation of DSM-TV to incorporate an aware-
ness that the manual is used in culturally diverse populations in the United States and
I
xxxiv                                                                         Introduction


internationally. Clinicians are called on to evaluate individuals from numerous dif-
ferent ethnic groups and cultural backgrounds (including many w ho are recent im-
migrants). Diagnostic assessment can be especially challenging ·wh en a clinician from
one ethnic or cultural group uses the DSM-IV Oassification to evaluate an individual
from a different ethnic or cultural group. A clinician w h o is unfamiliar with the nu-
ances of an individual's cultural frame of reference may incorrectly judge as psycho-
pathology those normal variations in behavior, belief, or experience that are
particular to the individual 's culture. For example, certain religious practices or be-
liefs (e.g., hearing or seeing a deceased relative during bereavement) may be misdi-
agnosed as manifestations of a Psychotic Disorder. Applying Personality Disorder
criteria across cultttr~ settings may be especially difficult because of the wide cultur-
al variation in concepts of self, styles of communication, and coping m echanisms.
   DSM-IV includes three types of information specifically related to cultural consid-
erations: 1) a discussion in the text of cultural variations in the clinical presentations
of those disorders that h ave been included in the DSM-IV Classification; 2) a descrip-
tion of culture-bound syndromes that have not been included in the DSM-IV Classi-
fication (these are included in Appendix I); and 3) an outline for cultural fomllllation
designed to assis t the clinician in systematically evaluating and reporting the impact
of the individual's cultural context (also in Appendix I).
   The wide international acceptance of DSM s ugges ts that this classification is useful
in describing mental disorders as they are experienced by individuals throughout the
world. Nonetheless, evidence also suggests that the symptoms and course of anum-
ber ofDSM-IV disorders are influenced by cultural and ethnic factors. To facilitate its
application to individuals from diverse cultural and ethnic settings, DSM-IV includes
a new section in the text to cover culture-related features. 1ltis section describes the
ways in 'vhich varied cultural backgrounds affect the content and form of the symp-
tom presentation (e .g., depressive disorders characterized by a preponderance of so-
matic symptoms rather than sadness in certain culhues), preferred idioms for
describing distress, and information on prevalence ,., hen it is available.
   The second type of cultural information provided pertains to "culture-bound S)rn-
dromes'' that have been described in just one, or a few, of the world's societies. DSM-IV
provides hvo ways of increasing the recognition of culture-bound syndromes: 1) some
(e.g., amok, ataque de nervios) are included as separate examples in Not Otherwise
Specified categories; and 2) an appendix of culture-bound syndromes (Appendix I)
has been introduced in DSM-IV that includes the name for the condition, the cultures
in which it was first described, and a brief description of the p sychopathology.
   The provision of a culture-specific section in the DSM-IV text, the inclusion of a
glossary of culture-bound syndrom es, and the provision of an outline for cultural for-
mulation are designed to enhance the cross-cultural applicability of DSM-IV. It is
hoped that these new features will increase sensitivity to variations in how mental
disorders may be expressed in d ifferent cultures and will reduce the possible effect of
 unintended b ias stemming from the clinician's mvn cultural background.


    Use of DSM-IV in Treatment Planning
    Making a DSM-IV diagnosis is only the first step in a comprehensive evaluation. To
    formulate an adequate treatment plan, the clinician v.rilJ. invariably require consider-
Introduction                                                                     XXXV


able additional information about the person being evaluated beyond that required
to make a DSM-IV diagnosis.


Distinction Between Mental Disorder and
General Medical Condition
The terms mental disordeJ" and gellernl medicnl condition are used throughout this man-
ual The term me11tnl disorder is explained above. The term general medical co11ditio11 is
used merely as a convenient shorthand to refer to conditions and disorders that are
listed outside the '1Y1ental and Behavioural Disorders" chapter of ICD. It should be
recognized that these are merely terms of convenience and should not be taken to im-
p ly that there is any fundamental distinction behveen mental disorders and general
medical conditions, that mental disorders are unrelated to physical or biological fac-
tors or processes, or that general medicaJ conditions are unrelated to behavioral or
psychosocial factors or processes.


                    Organization of the Manual
The manual begins with instructions concerning the use of the manual (p. 1), followed
by the DSM-IV-TR Classification (pp. 13-26), which provides a systematic listing of
the official codes and categories. Next is a description of the DStvl-IV Multiaxial Sys-
tem for assessment (pp. 27-37). This is followed by the diagnostic criteria for each of
the DSM-IV d isorders accompanied by descriptiv e text (pp. 39-743). Finally, DSM-N
includes 11 appendixes.
Cautionary Statement



         he specified diagnostic criteria for each mental disorder are offered as guidelines
    ior making diagnoses, because it has been demonstrated that the use of such criteria
    enhances agreement among clinicians and investigators. The proper use of these cri-
    teria requires specialized clinical training that provides both a body of knowledge
    and clinical skills .
       These diagnostic criteria and ·the DSM-rv Classification of m ental disorders reflect
    a consensus of current formulations of evolving knowledge in our field . They do not
    encompass, however, all the conditions for which people may be treated or that may
    be appropriate topics for research efforts.
       The purpose of DSM-N is to provide clear descriptions of diagnostic categories in
    order to enable clinicians and investigators to diagnose, communicate about, study,
    and treat people with v arious mental disorders. It is to be understood that inclusion
    here, for clinical and research purposes, of a diagnos tic category such as Pathological
    Gambling or Pedophilia does not imply that the condition meets legal or other non-
    medical criteria for what constitutes mental disease, mental disorder, or mental dis-
    ability. The clinical and scientific considerations involved in categorization of these
    conditions as mental disorders may not be wholly relevant to legal judgments, for
    example, that take into account such issues as individual responsibility, disability
    determination, and competency.




                                                  ••
                                           XXXVII
I
Use of the Manual



               Coding and Reporting Procedures

Diagnostic Codes
The official coding system in use in the United States as of publication of thjs manual
is the l11tematiollal Classifimtion of Diseases, Ninth Revision, Clinical Modification
(ICD-9-CM). Most DSM-IV disorders have a numerical ICD-9-CM code that appears
several times: 1) preceding the name of the disorder in the Classification (pp. 13-26),
2) at the beginning of the text section for each disorder, and 3) accompanying the cri-
teria set for each disorder. For some diagnoses (e.g., Mental Retardation, Substance-
Induced Mood Disorder), the appropriate code depends on further specification and
is listed after the text and criteria set for the disorder. The names of some djsorders
are followed by alternative terms enclosed in parentheses, which, in most cases, were
the DSM-ID-R names for the disorders.
   The use of diagnostic codes is fundamental to medical record keeping. Diagnostic
coding facilitates data collection and retrieval and compilation of statistical informa-
tion. Codes also are often required to report diagnostic data to interested third parties,
including governmental agencies, private insurers, and the World Health Organiza-
tion. For example, in the United States, the use of these codes has been mandated by
the Health Care Financing Administration for purposes of reimbursement under the
Medicare system.
    Subtypes (some of which are coded in the fifth digit) and specifiers are provided
for increased specificity. Subh;pes define mutually exclusive and jointly exhaustive
phenomenological subgroupings within a diagnosis and are indicated by the instruc-
tion "specify type" in the criteria set. For example, Del.i.~s ional Disorder is subtyped
based on the content of the delusions, with seven subtypes provided: Erotomanic
Type, Grandiose Type, Jealous Type, Persecutory Type, Somatic Type, lvlixed Type,
and Unspecified Type. ln contrast, specifiers are not intended to be mutually exclusive
or jointly exhaustive and are indicated by the instruction "specify" or "specify if" in
the criteria set (e.g., for Social Phobia, the instruction notes "Specify if: Generalized").
Specifiers provide an opportunity to define a more homogeneous subgrouping of
individuals with the disorder who share certain features (e.g., Major Depressive Dis-
order, With Melancholic Features). Although a fifth digit is sometimes assigned to
code a subtype or specifier (e.g., 294.11 Dementia of the Alzheimer's Type, With l.ate
Onset, With Behavioral Disturbance) or severity (296.21 Major Depressive Disorder,
Single Episode, Mild), the majority of subtypes and specifiers included in DSM-IV
cannot be coded w ithin the ICD-9-CM system and are indicated only by including the
subtype or specifier after the name of the disorder (e.g., Social Phobia, Generalized).

                                             1
2                                                                    Use of the Manual


Severity and Course Specifiers
A DSM-N diagnosis is usually applied to the individual's current presentation and is
not typically used to denote previous diagnoses from v.rhich the individual has recov-
ered. The following specifiers indicating severity and course may be listed after the
diagnosis : Mild, Moderate, Severe, In Partial Remission, In Full Remission, and Prior
His tory.
   The sp ecifi ers Mild, Moderate, and Severe should be used only when the full cri-
teria for the disorder are currently met. In deciding whether the presentation should
be described as mild, moderate, or severe, the clinician should take into account the
number and intensity of the signs and symptoms of the disorder and any resulting
impairment in occupatioQal or social functioning. For the majority of disorders, the
following g uidelines may be used:
       Mild. Few, if any, symptoms in excess of those required to make the diagno-
       sis are present, and symptoms result in no more than minor impairment in so-
       cial or occupational functioning.
       Moderate. Symptoms or functional impairment between "mild" and "se-
       vere" are present.
       Severe. Many symptoms in excess of those required to make the diagnosis,
       or several symptoms that are particularly severe, are present, or the symptoms
       result in marked impairment in social or occupational functioning.
       In Partial Remission. The full criteria for the disorder w ere previously met,
       but currently only some of the symptoms or signs of the disorder remain.
       In Full Remission. There are no longer any symptoms or signs of the dis-
       order, but it is still clinically relevant to note the disorder- for example, in an
       individual w ith previous episodes of Bipolar Disorder w ho has been symptom
       free on lithium for the past 3 y ears. After a period of time in full remission, the
       clinician may judge the individual to be recovered and, therefore, would no
       longer code the disorder as a current diagnosis. The differentiation of In Full
       Remission from recovered requires consideration of many factors, including
       the characteristic course of the disorder, the length of time since the last period
       of disturbance, the total duration of the disturbance, and the need for contin-
       ued evaluation or prophylactic treatment.
       Prior History. For some purposes, it may be useful to note a history of the
       criteria having been met for a disorder even when the individual is considered
       to be recovered from it. Such past diagnoses of mental disorder would be in-
       dicated by us ing the specifier Prior History (e.g., Separation Anxiety Disorder,
       Prior History, for an individual '"'ith a history of Separation Anxiety Disorder
       wh o has n o current disorder or ·who currently meets criteria for Panic Dis-
       order).

   Specific criteria for defining Mild, Moderate, and Severe have been provided for
the following: Mental Retardation, Conduct Disorder, Manic Episode, and Major
Depressive Episode. Specific criteria for defining In Partial Remission and In Full
Remission hav e been provided for the follow ing: Manic Episode, Major Depressive
Episode, and Substance Dependence.
Use of the Manual


Recurrence
Not infrequently in clinical practice, individuals after a period of time in which the
full criteria for the disorder are no longer met (i.e., in partial or full remission or re-
covery) may develop symptoms that suggest a recurrence of their original disorder
but that do not yet meet the full threshold for that disorder as specified in the criteria
set. It is a matter of clinical judgment as to how best to indicate the presence of these
symptoms. The following options are available:

• If the symptoms are judged to be a new episode of a recurrent condition, the dis-
  order may be diagnosed as current (or provisional) even before the fuJJ criteria
  have been met (e.g., after meeting criteria for a Major Depressive Episode for only
  10 days instead of the 14 days usuaJiy required).
• If the symptoms are judged to be clinically significant but it is not clear whether
  they constitute a recurrence of the original disorder, the appropriate Not Other-
  wise Specified category may be given.
• If it is judged that the symptoms are not clinkally significant, no additional current
  or provisional diagnosis is given, but ''Prior History" may be noted (seep. 2).


Princi pal Diagnosis/Reason for Visit
When more than one diagnosis for an individual is given in an inpatient setting, the
principal diagnosis is the condition established after study to be chiefly responsible for
occasioning the admission of the individual. When more than one diagnosis is given
for an individual in an outpatient setting, the reason for visit is the condition that is
chiefly responsible for the ambulatory care medical services received during the visit.
In most cases, the principal diagnosis or the reason for visit is also the main focus of
attention or treatment. It is often difficult (and some·what arbitrary) to determine
which diagnosis is the principal diagnosis or the reason for visit, especially in situa-
tions of "dual diagnosis" (a substance-related diagnosis like Amphetamine Depen-
dence accompanied by a non-substance-related diagnosis like Schizophrenia). For
example, it may be unclear which d iagnosis should be considered "principal" for an
individual hospitalized with both Schizophrenia and Amphetamine Intoxication, be-
cause each condition may have contributed equally t<l the need for admission and
treatment.
   Multiple diagnoses can be reported in a multiaxial fashion (seep. 35) or in a non-
axial fashion (seep. 37). When the principal diagnosis is an Axis I disorder, this is in-
dicated by listing it first. The remaining disorders are listed in order of focus of
attention and treatment. When a person has both an Axis I and an Axis II diagnosis,
the principal diagnosis or the reason for visit will be assumed to be on Axis I unless
the Axis II diagnosis is followed by the qualifying phrase "(Principal Diagnosis)" or
 "(Reason for Visit)."


Provisional Diagnosis
The s p ecifier provisional can be used when there is a strong presumption that the full
criteria will ultimately be met for a disorder, but not enough information is available
4                                                                      Use of the Manual

to make a firm diagnosis. The clinician can indicate the diagnostic uncertainty by re-
cording "(Provisional)" following the diagnosis. For example, the individual appears
to have a Major Depressive Disorder, but is unable to give an adequate history toes-
tablish that the full criteria are met. Another use of the term provisional is for those sit-
uations in ,vhich differentia] diagnosis depends exclusively on the dLUation of illness.
For example, a diagnosis of Schizophreniform Disorder requires a duration of Jess
than 6 months and can only be given provisionalJy if assigned before remission has
occurred.


        Use of Not Otherwise Specified Categories
Because of the diversity of dinicalprese.ntations, it is impossible for the diagnostic no-
menclature to cover every possible situation. For this reason, each diagnostic class has
at least one Not Otherwise Specified (NOS) category and some classes have several
NOS categories. There are foill situations in which an NOS djagnosis may be appro-
priate:

• The presentation conforms to the general gwdelines for a mental disorder in the
  diagnostic class, but the symptomatic picture does not meet the criteria for any of
  the specific disorders. This would occur either when the symptoms are belov..• the
  diagnostic threshold for one of the specific disorders or when there is an atypical
  or mixed presentation.
• The presentation conforms to a symptom pattern that has not been included in the
  DSM-TV Classification but that causes clinicalJy significant distress or impairment.
  Research criteria for some of these symptom patterns have been included in Appen-
  dix B ("Criteria Sets and Axes Provided for Further Study"), in which case a page
  reference to the suggested research cdteria set in Appendix B is provided.
• There is uncertainty about etiology (i.e., .-. rhether the disorder is due to a general
  medicaJ condition, is substance mduced, or is primary).
• There is insufficient opportunity for complete data collection (e.g., in emergency
  situations) or inconsistent or contradictory information, but there is enough infor-
  mation to place itwitl1in a particuJar diagnostic class (e.g., the clinician determines
  that tl1e indhridual has psychotic symptoms but does not have enough information
  to diagnose a specific Psychotic Disorder).


        Ways of Indicating Diagnostic Uncertainty
The following table indicates the various ways in which a clinician may indicate di-
agnostic uncertainty:
Use of the Manual                                                                        sl
Term                                         Examples of clinical situations

V Codes (for Other Conditions That May       Insufficient information to know whether or
Be a Focus of Clinical Attention)            not a presenting problem is attributable to a
                                             mental disorder, e.g., Academic Problem;
                                             Adult Antisocial Behavior

799.9   Diagnosis or Condition Deferred on Information inadequate to make any diag-
        Axis I                             nostic judgment about an Axis I diagnosis or
                                           condition

799.9   Diagnosis Deferred on Axis II        Information inadequate to make any diag-
                                             nostic judgment about an Axis II diagnosis

300.9   Unspecified Mental Disorder          Enough information available to rule out a
        (non psychotic)                      Psychotic Disorder, but further specification
                                             is not possible

298.9   Psychotic Disorder Not Otherwise     Enough information available to determine
        Specified                            the presence of a Psychotic Disorder, but fur-
                                             ther specification is not possible

(Class of disorder] Not Otherwise Specified Enough information available to indicate
e.g., Depressive Disorder Not Otherwise     the class of disorder that is present, but fur-
Specified                                   ther specification is not possible, either be-
                                            cause there is not sufficient information to
                                            make a more specific diagnosis or because
                                            the clinical features of the disorder do not
                                            meet the criteria for any of the specific cate-
                                            gories in that class

[Specific diagnosis] (Provisional)           Enough information available to make a
e.g., Schizophreniform Disorder              "working" diagnosis, but the clinician wishes
(Provisiona I)                               to indicate a significant degree of diagnostic
                                             uncertainty



                        Frequently Used Criteria
                                          . . ,. ,

Criteria Used to Exclude Other Diagnoses and
to Suggest Differential Diagnoses
Most of the criteria sets presented in this manual include exclusion criteria that are
necessary to establish boundaries between disorders and to clarify differential diag-
noses. The several different w ordings of exclusion criteria in the criteria sets through-
out DSM-IV reflect the different types of possible relationships among disorders:

• "Criteria have never been met for ... " This exclusion criterion is used to define
  a lifetime hierarchy behveen disorders. For example, a diagnosis of M ajor Depres-
  sive Disorder can no longer be given once a Manic Episode has occurred and must
  be cl1anged to a diagnosis of Bipolar I Disorder.
Use of the Manual

• "Criteria are n ot met for ..." Thls exclusion criterion is used to establish a hier-
  archy between disorders (or subtypes) defined cross-sectionally. For example, the
  specifier With Melancholic Features takes precedence over With Atypical Features
  for describing the current Major Depressive Episode.
• udoes not occur exclusively during the course of . .." This exclusion criterion
  prevents a disorder from being diagnosed when its symptom presentation occurs
  only during the course of another disorder. For example, dementia is not diag-
  nosed separately if it occurs only during d elirium; Conversion Disorder is not
  diagnosed separately if it occurs only during Somatization Disorder; Bulimia Ner-
  vosa is not diagnosed separately if it occurs only during episodes of AnorexiaNer-
  vosa. This exclusion criterion is typically used in situations in which the symptoms
  of one disorder are associated features or a subset of the symptoms of the preempt-
  ing disorder. The clinician should consider periods of partial re:rrUssion as part of
  the "course of another disorder." It should be noted that the excluded diagnosis
  can be given at times when it occurs independently (e.g., when the excluding dis-
  order is in full remission).
• "n ot d ue to the direct physiological effects of a substance (e.g., a drug of abuse,
  a medication) or a general medical condition." This exclusion criterion is used
  to indicate that a substance-induced and general medical etiology must be consid-
  ered and ruled out before the disorder can be diagnosed (e.g., Major Depressive
  Disorder can be diagnosed only after etiologies based on substance use and a gen-
  eral medical condition have been ruled out).
• "not better accounted for by .. .'' This exclusion criterion is used to indicate that
  the disorders mentioned in the criterion must be considered in the differential di-
  agnosis of the presenting psychopathology and that, in boundary cases, clinical
  judgment ·w jJl be necessary to deter:rrUne whicl1 disorder provides the most appro-
  priate diagnosis. In such cases, the "Differential Diagnosis" section of the text for
  the disorders should be consulted for guidance.
   The general convention in DSM-N is to allow multiple diagnoses to be assigned
for those presentations that meet criteria for more than one DSM-N disorder. There
are three situations in which the above-mentioned exclusion criteria help to establish
a diagnostic hierarchy (and thus prevent multiple diagnoses) or to highlight differen-
tial diagnostic considerations (and thus discourage multiple diagnoses):

• When a Mental Disorder Due to a General Medical Condition or a Substance-
  Induced Disorder is responsible for the symptoms, it preempts the diagnosis of the
  corresponding primary disorder with the same symptoms (e.g., Cocaine-Induced
  Mood Disorder preempts Major Depressive D isorder). In such cases, an exclusion
  criterion containing the phrase "not d ue to the direct physiological effects of ... "
  is included in the criteria set for the primary disorder.
• When a more pervasive disorder (e.g., Schizophrenia) has among lts defining
  symptoms (or associated symptoms) what are the defining symptoms of a les.s per-
  vasive disorder {e.g., Dysthymic Disorder), one of the following three exclusion
  criteria appears in the criteria set for the less pervasive disorder, indicating that
  only the more pervasive disorder is diagnosed: "Criteria have never been met
  for ...," "Criteria are not met for ...," "d oes not occur exclusively during the
  course o,f ... "
Use of the Manual


• When there are particularly difficult differential diagnostic boWldaries, the phrase
  "not better accoWlted for by ..." is included to indicate that clinical judgment is
  necessary to determine which diagnosis is most appropriate. For example, Panic
  Disorder With Agoraphobia includes the criterion "not better accounted for by
  Social Phobia" and Social Phobia includes ihe criterion "not better accounted for
  by Panic Disorder Y'lith Agoraphobia" in recognition of the fact that this is a par-
  ticularly difficult boundary to draw. In some cases, both ruagnoses might be
  appropriate.


Criteria for Substance-Induced Disorders
l tis often difficult to determine whether presenting symptomatology is substance in-
duced, that is, the direct physiological consequence of Substance Intoxication or
Withdrawal, medication use, or toxin exposure. In an effort to provide some assis-
tance in making this determination, the hvo criteria listed below have been added to
each of the Substance-Induced Disorders. These criteria are intended to provide gen-
eral guidelines, but at the same time allow for clinical judgment in determining
·whether or not the presenting symptoms are best accoWlted for by the direct physio-
logica l effects of the substance. For further discussion of this issue, seep. 209.

     B.   There is evidence from the history, physical examination, or laboratory
          findings of either (1) or (2):
          {1) the symptoms developed during, or w ithin a month of, Substance
              Intoxication or Withdrawal
          {2) medication use is etiologically related to the disturbance
     C.   The disturbance is not better accounted for by a disorder that is n ot sub-
          stance induced. Evidence that the symptoms are better accounted for by a
          disorder that is not s ubstance induced might include the following: the
          symptoms precede the onset of the substance use (or medication use); the
          symp toms persist for a substantial period of time (e.g., about a month) after
          the cessation of acute withdrawal or severe intoxication, or are substantial-
          ly in excess of what would be expected given the type, duration, or amount
          of the s ubstance used; or there is other e'ridenc~ that suggests the existence
          of an independent non-substance-induced disorder (e.g., a history of recur-
          rent non-substance-related episodes).


Criteria fo r a Mental Disorder Due to a
General Medica l Condition
The criterion listed below is necessary to establis h the etiological requirement for
each of the Mental Disorders Due to a General Medical Condition (e.g., Mood Disor-
der Due to H ypothyroidism). For further discussion of this issue, seep. 181.
      There is evidence from the history, physical examination, or laboratory find-
      ings that the disturbance is the rurect physiological consequence of a general
      medical condition.
Is                                                                    Use of the Manual


Criteria for Clinical Significance
The definition of mental disorder in the introduction to DSM-IV requires that there be
dinjcally significant impairment or distress. To highlight the importance of consider-
ing this issue, the criteria sets for most disorders include a clinical significance crite-
rion (usually worded"... causes dinjcally significant distress or impairment in social,
occupational, or other important areas of functioning"). This criterion helps establish
the threshold for the diagnosis of a disorder in those situations in which the symp-
tomatic presentation by itself (particu1arly in its milder forms) is not inherently
pathological and may be encountered in individuals for whom a diagnosis of " mental
disorder" would be inappropriate. Assessing whether this criterion is met, especially
in terms of role funcpon, is an inherently difficult clinical judgment Reliance on in-
fom"ta tion from family members and other third parties (in addition to the individu al)
regarding the individual's performance is often necessary.


          Types of Information in the DSM-IV Text
The text of DSM-IV systematically describes each disorder under the following head-
ings: "Diagnostic Features"; "Subtypes and/ or Specifiers"; "Recording Procedures";
"Associated Features and Disorders"; "Specific Culture, Age, and Gender Features'';
"Prevalence"; "Course"; "Familial Pattern"; and "Differential Diagnosis." When n o
information is available for a section, that section is not included. In some instances,
when many o f the specific d isorders in a group of disorders share common features,
this information is included in the general introduction to the group.

D iagnostic Features. This section clarifies the diagnostic criteria and often provides
illustrative examples.

Subtypes and/or Specifiers. This section provides definitions and brief discussions
concerning applicable subtypes and / or specifiers.

Recording Procedures. This section provides guidelines for reporting the name of
the disorder and for selecting and recording the appropriate ICD-9-CM diagnostic
code. It also includes instructions for applying any appropriate subtypes and/ or
specifiers.

Associated Features and Disorders. This section is usually subdivided into three
parts:

• Associated descriptive features mrd me11tal disorders. This section includes clinical
   features that are frequently associated w ith the disorder but that are not consid-
   ered essential to making the diagnosis. In some cases, these features were consid-
   ered for inclusion as possible diagnostic criteria but>vereinsufficiently sensitive or
   specific to be included in the final criteria set. Also noted in this section are other
   mental disorders associated with the disorder being discussed. It is specified
   (when known) if t11ese disorders p recede, co-occur Vith, or are consequen ces of the
   disorder in question (e.g., Alcohol-Induced Persisting Dementia is a consequence



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28543941 dsm-iv-tr

  • 1. ~- , : .. - -. - ·=- -~ : - ' • - • - - • - • . - - •- - DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS FOURTH EDITION TEXT REVISION TM - - 184 4 _- . . . _-_· - ----· -. . . Published by the American Psychiatric Association Washington, DC - '
  • 2. Copyright© 2000 American Psychiatric Association DSM, DSM-IV, and DSM-IV-TR are trademarks of the American Psychiatric Association. Use of these terms is prohibited without permission of the American Psychiatric Association. ALL RIGHTS RESERVED. Unless authorized in writing by the APA, no part of this book may be reproduced or used in a manner inconsistent with the AP A's copyright. This prohibition ap- plies to unauthorized uses or reprod1,1 ctions in any fom1, including electronic applications. Correspondence regarding copyright permissions should be directed to the DSM Permissions, Office of Publishing Operations, American Psychiatric Association, 1400 K Street, N.W., Wash- ington, DC 20005. Manufactured in the United States of America on acid-free paper. American Psychiatric Association 1400 K Street, N.N., Washington, DC 20005 www.psych.org The correct citation for this book is American Psychiatric Association: Diagnostic and Sialisticnl M.n1mal of Mental Disorders, Fourth Edition, Text Revision. Washington, DC, American Psychi- atric Association, 2000. Library of Congress Cataloging-in-Publication Data Diagnostic and statistical manual of mental disorder5 : OSM-IV.~th ed., text revision. p. ; em. Prepared by the Task Force on OSM-IV and other committees and work groups of the Amer- ican Psychiatric Association. Includes index. IS B1 0-89042-02+6 (casebound: a1k. paper}-ISB1 0-89042-025--! (pbk : alk. paper) l. Mental illness-Classification-Handbooks, manuals, etc. 2. Mental illness-Diagnosis- H andbooks, manuals, etc. I. Title: DSM-IV. IT. American Psycltiatric Association. ill. American Psychiatric Association. Task Force on DSM-IV. [DNLM: 1. Mental Disorders-classification. 2.. Mental Disorders-diagnosis. VM 15 D536 2000} RC!55.2..C! D536 2000 616.89'075--dc21 00-024852 British Library Cataloguing in Publication Data A ClP record is available from the British library. Text Design- Anne Barnes Manufacturing-R. R. Oonnelley & Sons Company
  • 3. Contents - Task Force on DSM-IV .. .. ............................. ... xi Work Groups for the DSM-IV-TR Text Revision ............ .. . xv Acknowledgments for DSM-IV-TR ..... .... ................ xix Acknowledgments for DSM-IV Text Revision ... .. .............. . ............. .. xxi . ... Introd UctiOn . . . . . . . . . . . ....... . . . . . . . . . . . . . . . . . . . . . . .. XXIII Cautionary Statement .. .......... .................... xxxvii Use of the Manual ... .... . ......................... . ..... 1 DSM-IV-TR Classification ................................. 13 Multiaxial Assessment ..................... . ... .. . . . ..... 27 Disorders Usually First Diagnosed in Infancy, Childhood, or Adolescence . ................ . .... .. 39 Delirium, Dementia, and Amnestic and Other Cognitive Disorders ...... .... .... .... ............. 135 Mental Disorders Due to a General Medical Condition .. . ..... 181 Substance-Related Disorders .............. , . . ...... .. .... 191 Schizophrenia and Other Psychotic Disorders . ......... ..... .. .............. 297 Mood Disorders .... .. ............................. .. .. 345 Anxiety Disorders . .. .. ...................... . ..... .. ... 429 Somatoform Disorders ........ . ........... . ....... . .. . . .485 Factitious Disorders ..... ... ......... . .......... .. . . .... 513 Dissociative Disorders .. . ...... ...... ............. ... .... 519 Sexual and Gender Identity Disorders . ...... ..... .. ........ 535
  • 4. --- Eating Disorders ............. ..... ......... .......... .. 583 Sleep Disorders . . ... .......... .. . .. . ................... 597 Impulse-Control Disorders Not Elsewhere Classified ..... . ... . 663 Adjustment Disorders ..................... .......... ... 679 Personality Disorders .......... ............. .. ... . . . . . .. 685 Other Conditions That May Be a Focus of Clinical Attention ...... ............. . .......... 731 Additional Codes ................... ..... ......... ..... 743 Appendix A Decision Trees for Differential Diagnosis ......... ... ....... 745 Appendix B Criteria Sets and Axes Provided for Further Study .. . ......... 759 Appendix C Glossary of Technica l Terms ....... ... . .............. . ... . 819 Appendix D High lights of Changes in DSM-IV Text Revision ................................ ... 829 Appendix E Alphabetical Listing of DSM-IV-TR Diagnoses and Codes ......................... 845 Appendix F Numerical Listing of DSM-IV-TR Diagnoses and Codes ..... . ...... ........ . . ... 857 Appendix G ICD-9-CM Codes for Selected General Medical ·- Conditions and Medication-Induced Disorders . ............. 867
  • 5. Appendix H DSM-IV Classificatio n (With ICD- 10 Codes) ....................................883 - Appendix I Outline for Cultural Formu lation and Glossary of Culture-Bound Syndr omes ...... .. ... . .. ...... . 897 Appendix J DSM-IV Contributors ..................... ... . ..... . .. .. 905 Appendix K DSM-IV Text Revision Advisers .. . .. . . ..................... 929 Index ........ . ........................ .... . . ........ . 933
  • 6. TASK FORCE ON DSM -IV ALLEN FRANCES, M.D. Clzairpers011 HAROLD ALAN PINCUS, M .D. Vice-Chairperson MICHAEL B. FIRsT, M .D. Editor, Text and Criteria N ancy Coover Andreasen, M.D., Ph.D. Chester W. Schmidt, M.D. David H. Barlow, Ph.D. Marc Alan Schuckit, M.D. Magda Campbell, M.D. David Shaffer, M.D. Dennis P. Canhve11, MD. Robert L. Spitzer, M.D. Ellen Frank, Ph.D. Special Adviser Judith H. Gold, M.D. Gary J. Tucker, M.D. John Gunderson, M.D. B. Timothy Walsh, M.D. Robert E. Hales, M.D. Thomas A. Widiger, Ph.D. Kenneth S. Kendler, M.D. Research Coordinator Janet B. W. Williams, D.S.W. David J. Kupfer, M.D. Jolm C. Urbaitis, M.D. Michael R. Liebowitz, M.D. Assembly Liaison Juan Eruique Mezzich, M.D., Ph.D. James J. Hudziak, M.D. Peter E. N athan, Ph.D. Reside11t Fellow (199G-1993) Roger Peele, M.D. Junius Gonzales, M.D. Darrel A. Regier, M.D., M.P.H. Resident Fellow (1988-1990) A. Jolm.Rush, M.D. Ruth Ross, M.A. Scie11ce Editor N ancy E. Vettorello, M.U.P. Administrative Coordinator .._ Wendy Wakefield DaYis, Ed.M. Editorial Coordinator Cindy D . Jones Admi11istrntive Assistant N ancy Sydnor-Greenberg, M.A. Administmtive Consultmzt Myriam Kline, M.S. Focused Field-Trial Coordinator James W. Thompson, M.D., M.P.H. Videotape Field-Trial Coordinator The DSM-IV Text Reision Work Groups are listed on pp. xv-.wii. • XI
  • 7. •• XII DSM-IV Work Groups Anxiety Disorders Work Group 'Michae l R. Liebowitz, M.D. James C. Ballenger, M.D. Chn irpers011 Jonathan Davidson, M .D. David H. BarlOv, Ph.D. Edna Foa, Ph.D. Vice· Chn irperson Abby Fyer, M.D . Delirium, Dementia, and Amnestic and Other Cognitive Disorders Work Group Gary J. Tucker, M.D. Marshall Folstein, M.D. Clmirperson Gary Lloyd Gottlieb, M.D. Michae l Popkin, M.D. Igor Grant, LD. Vice-Chnirperso11 Benjamin Liptzin, M.D. Eric Douglas Caine, M .D. Disorders Usually First Diagnosed During Infancy, Childhood, or Adolescence Work Group David Shaffer, M .D . Rachel Klein, Ph.D. Co-Cimirpersou Benjamin Lahey, Ph.D. Magda Campbell, M .D. Rolf Loeb e r, Ph.D. Co-Cimi1111?TSOII Jeffrey Newcom, M.D. Susan J. Bradley, M .D. Rhea Paul, Ph.D. Dennis P. Cantwell, M.D. Judith H. L. Rapoport, M .D. Gabrielle A. Carls on, M.D. Sir Michael Rutter, M.D. Donald Jay Cohen, M .D. Fred Volkmar, M.D. Barry Garfinkel, M.D. • JohnS. Werry, M.D . Eating Disorders Work Group B. Timotl1y Walsh, M.D. Katherine A. Halmi, M.D. Clinirperso11 James Mitchell, lvl.D. Paul Garfinkel, M .D. G. Terence Wilson, Ph.D. Mood Disorders Work Group A. John Rush, M.D. David Dunner, M.D. Chairperson Ellen Frank, Ph.D. Martin B. Keller, M.D. Donald F. Klein, M.D. Vice-Ciwirperso11 Mark S. Bauer, lvLD. .,
  • 8. DSM-IV Work Groups xiii I Multiaxial Issues Work Group Janet B. W. Williams, D.S.W. Juan Enrique Mezzich, M .D.APh.D : Chairperson Roger Peele, M.D. Howard H. Goldman, M.D., Ph.D. Stephen Setterberg, M.D. Vice-Chnirpersoil Andrew Edward Skodol IT, M.D. Alan M. Gruenberg, M.D. Personality Disorders Work Group Jolm Gunderson, M.D. Theodore Millon, Ph .D. Chairperson Bruce Pfohl, M.D. Robert M.A. Hirschfeld, M.D. Tracie Shea, Ph.D. Vice-Clznirperson Larry Siever, M.D. Roger Blashfield, Ph.D. Thomas A. Widiger, Ph.D. Susan Jean Fiester, M .D. -.. Premenstrual Dysphoric Disorder Work Group Judith H. Gold, M.D. Sally Severino, MD. Chairperson N ada Logan Stotland, M.D. Jean Endicott, Ph.D. Ellen Frank, Ph.D. Barbara Parry, M.D. Cons11ltant Psychiatric Systems Interface Disorders (Adjustment, Dissociative, Factitious, Impulse-Contro l, and Somatoform Disorders and Psycholo gica l Factors Affecting Medical Conditions) Work Group Robert E. Hales, fvLD. Steven A. King, M.D. Chairperson Ronald L. Martin, M.D. C. Robert Cloninger, M.D. Kathaxine Anne Phillips, M.D. Vice-Chairperson David A. Spiegel, M.D. Jona than F. Borus, M.D. Alan Stoudemire, M.D. Jack Denning Burke, Jr., M.D., M.P.H. James J. Strain, M.D. Joe P. Fagan, M.D. Michael G. Wise, MD. Schizophrenia and Other Psychotic Disorders Work Group N ancy Coover Andreasen, M.D., Ph.D. Samuel Keith, M.D. Chairperson Kenneth S. Kendler, M.D. John M. Kane, MD. Thomas M cGlashan, M.D. V ice-Cizn irperson
  • 9. • XIV DSM-IV Work Groups Sexual Disorders Work Group Chester W . Schmidt, M.D. Leslie Schover, Ph.D. Chairperson Taylor Seagraves, M .D. Rau] Schiavi, M.D. Thomas N athan W ise, M.D. Sleep Disorders Work Group David J. Kupfer, M.D. Roger Peele, M.D. Chairperson Quentin Regestein, M.D. Charles F . Reynolds III, M .D. Michael Sateia, M.D. Vice-Cl111i rperson Michael Thorpy, M.D . Daniel Buysse, M.D. Substance-Related Disorders Work Group Marc Alan Schuckit, M.D . Linda B. Cottier, Ph.D. Chairperson Thomas Crm,.rley, M.D. John E. Helzer, M.D. Peter E. N athan, Ph.D. Vice-Chairperson George E. Woody, M.D. Committee on Psychiatric Diagnosis and Assessment Layton McCurdy, M.D. Jerry M. Lewis, M.D. Chairperson (1987- 1994) Consultant (1988-1994) Kenneth Z. Altshuler, M .D. (1987-1992) Daniel J. Luc.hin.s, M.D. Thomas F. Anders, M.D. (1988-1994) Consultant (1987-1991) Susan Jane Blumenthal, M.D. (1990- Katharine Anne Phillips, M .D. 1993) Con51tltant (1992- 1994) Leah Joan Dickstein, M .D. (1988-1991 ) Cynthia Pearl Rose, M .D. Consultant (1990-1994) Lewis J. Judd, M .D. (1988-1994) Louis Alan Moench, M.D. Gerald L. Klerman, M .D. (deceased) Assembly Liaison (1991- 1994) (1988-1991) Steven K. Dobscha, M.D. Stuart C. Yudofsky, M .D. (1992- 1994) Resident Fellow (1990-1992) Jack D. Blaine, M .D. Mark Zimmerman, M.D . Consultant (1987-1992) Resident Fellow (1992-1994) Joint Committee of the Board of Trustees and Assembly of District Branches on Issues Related to DSM-IV Ronald A. Shello'"' , M.D. Leah Joan Dickstein, M .D. Chairperson -..... Arthur John Farley, M.D. Harvey Bluestone, M.D. Carol A nn Bernstein, M.D.
  • 10. 1 WORK GROUPS FOR THE DSM-IV TEXT REVISION J1ICHAEL B. FIRsT, M .D. Co-Chairperson and Editor H AROLD ALA!J P INCUS, M.D. Co-Clwirperson Laurie E. McQueen, M.S.S.'W. Yoshie Satake, B.A. DSM Project Manager DSM Program Coordi11ator Anxiety Disorders Text Revision Work Group Munay B. Stein, M.D. M ichelle Cra.ske, Ph.D. Chairperso11 Edna Foa, Ph.D. Jonathan Abrammvitz, Ph.D. Thomas M ellman, M.D. Gordon Asmundson, Ph.D. Ron N orton, Ph.D. Jean C. Beckham, Ph.D. Franktin Schneier, M.D. Timothy Brown, Ph.D., Psy.D. Richard Zinbarg, Ph.D. Delirium, Dementia, and Amnestic and Other Cognitive Disorders and Mental Disorders Due to a General Medical Condition Text Revision Work Group Eric Douglas Caine, M.D. Jesse Fann, M.D., M.P.H. Disorders Usually First Diagnosed During Infancy, Childhood, or Adolescence Text Revision Work Group David Shaffer, M.D. Ami Klin, Ph.D. Chairperson Daniei Pine, M.D. Donald J. Cohen, M.D. Mark A Riddle, M.D. Stephen Hinshaw, Ph.D. Fred R. Volkmar, M.D. Rachel G. Klein, Ph.D. Charles Zeanah, M.D. "' Eating Disorders Text Revision Work Group Katharine L. Loeb, Ph.D. B. Timothy Walsh, M.D. Medication-Ind uced Movement Disorders Text Revision Work Group Gerard Addonizio, M.D. Alan Gelenberg, M.D. Lenard Adler, M.D. James Jefferson, M .D. Burton Angrist, M.D. Dilip Jeste, M.D . Daniel Casey, M.D. Peter Weiden, M.D. XV
  • 11. Ixvi DSM-IV-TR Work Groups Mood Disorders Text Revision Work Group MarkS. Bauer, M.D. Michael E. Thase, M .D. Patricia Suppes, M.D., Ph.D. Multiaxial Text Revision Work Group Alan M. Gruenberg, M.D. Personality Disorders Text Revision Work Group Bruce Pfohl, M.D. Thomas A Wicliger, Ph.D. Premenstrual Dysphoric Disorder Text Revision Work Group Sally Severino, M.D. Psychiatric System Interface Disorders (Adjustment, Dissociative, Factitious, Impulse-Control, and Somatoform Disorders and Psychological Factors Affecting Medical Conditions) Text Revision Work Group Mitchell Cohen, M.D. Russell Noyes, Jr., M.D. Marc Feldman, M.D. Katharine Anne Phillips. M.D. Eric HolJander, M.D. Eyal Shemesh, M.D. Steven A. King, M.D . David A Spiegel, M.D. James Levenson, M.D. James J. Strain, M.D. Ronald L Martin, M.D. (deceased) Sean H. Yutzy, M.D. Jeffrey Iewcom , M.D. Schizophrenia and Other Psychotic Disorders Text Revision Work Group Michael Flaum, M.D. Xavier Amador, Ph.D. Chairperson Sexual and Gender Identity Disorders Text Revision W ork Group Chester W. Schnudt, M.D. Thomas Nathan Wise, M.D. R. Taylor Segraves, M.D. Kenneth J. Zucker, Ph.D. Sleep Disorders Text Revision Work Group Daniel Buysse, M.D. Peter Nowell, M .D. Substance-Related Disorders Text Revision Work Group Marc Alan Schuckit, M.D .
  • 12. DSM-IV-TR Work Groups xvii I American Psychiatric Association Committee on Psychiatric Diagnosis and Assessment David J. Kupfer, M.D. Louis Alan Moench, M.D. Chair Assembly Liaison James Leckman, M.D. Jack Barchas, lvLD. Member Corresponding Member Katharine Anne Phillips, M.D . Herbert W. Harris, M.D., Ph.D. Member Corresponding Member A. John Rush, M .D. Charles Kaelber, M.D. Member Corresponding Member Daniel Winstead, M.D. Jorge A. Cos ta e Silva, M.D. Member Corresponding Member Bonnie Zima, M.D., Ph.D. T. Bedirhan Ustun, M.D. Member Corresp01zding lviember Barbara Kennedy, M.D., Ph.D. Yeshuschandra Dhaibar, M.D. Co nsulta11 t APA/Glaxo-Wellcome Fellow Janet B. W. Williams, D .S.W. Consultant
  • 13. Acknowledgments for DSM-IV D SM-IV was a team effort. More than 1,000 people (and numerous professional organizations) have helped us in the preparation of this document. Members of the Task Force on DSM-IV and DSM-IV Staff are listed on p. xi, members of the DSM-IV Work Groups are listed on pp. ).:ii-xiv, and a list of other participants is included in Appendix J. The major responsibility for the content of DSM-IV rests with the Task Force on DSM-N and members of the DSM-IV Work Groups. They have worked (often much harder than they bargained for) with a dedication and good cheer that has been inspi- rational to us. Bob Spitzer has our special thanks for his untiring efforts and unique per- spective. Norman Sartorius, Darrel Regier, Lewis Judd, Fred Good·win, and Chuck Kaelber were instrumental in facilitating a mutually productive interchange between the American Psychiatric Association and the World Health Organization that has improved both DSM-N and ICD-10, and increased their compatibility . We are grate- ful to Robert Israel, Sue Meads, and Amy Blum at the N ational Center for Health Statistics and Andrea Albaum-Feinstein at the American Health Infom1ation Man- agement Association for suggestions on the DSM-IV coding system. Denis Prager, Peter Nathan, and David KupfeT helped us to develop a novel data reanalysis s trate- gy that has been supported with funding from the John D. and Catherine T. Mac- Arthur Foundation. Many individuals within the American Psychiatric Association deserve recogni- tion. Mel Sabshin's special wisdom and grace made even the most tedious tasks seem worth doing. The American Psychiatric Association Committee on Psychiatric Diag- nosis and Assessment (chaired by Lay ton McCurdy) provided valuable direction and cotmsel. We would also like to thank the American Psychiatric Association Presidents (Drs. Fink, Pardes, Benedek, Hartmann, English, and Mcintyre) and Assembly Speak- ers (Drs. Cohen, Flamm, Hanin, Pfaehler, and SheUow)....vho helped with the planning of our w ork Carolyn RobinO·vitz and Jack White, and their respective staffs in the American Psychiahic Association Medical Director's Office and the Business Admin- istration Office, have provided valuable assistance in the organization of the project. Several other individuals have our special gratitude. Wendy Davis, Nancy Vet- torello, and Nancy Sydnor-Greenberg developed and implemented an organizational structure that has kept this complex project from spinning out of control. We have also been blessed vvith an unusually able administrative s taff, ' "'hich has included Elisabeth Fitzhugh, t'hl.la Hall, Kelly McKinney, Gloria itliele, Helen Stayna, Sarah Tilly, N ina Rosenthal, Susan Mann, Joanne M as, and, especially, Cindy Jones. Ruth Ross, our tireless Science Editor, has been responsible for improving the cla1ity of ex- pression and organization of DSM-IV. Myriam Kline (Researd1 Coordinator for the NIH-funded DSM-IV Focused Field TriaJs), Jim Thompson (Research Coordinator for • XIX
  • 14. XX Acknowledgments for DSM-IV the MacArthur Foundation-funded Videotape Field Trial), and Sandy Ferris (Assis- tant Director for the Office of Research) have made many valuable contributions. We would also like to acknowledge all the other staff persons at the American Psychiatric Association who have helped with this project. Ron Mc.MHlen, Claire Reinburg, Pam Harley, and Jane Davenport of American Psychiatric Press h ave provided expert pro- duction assistance. Allen Frances, M.D. Cllairpersoll, Task Force 011 DSM-IV Harold Alan Pincus, M.D. Vice-Chairperson, Task Force 011 DSM-TV Michael B. First_ M.D. Editor, DSlvf-W Text nud Criteria TI·10mas A. Widiger, Ph.D. Research Coordinator
  • 15. Acknowledgments for DSM-IV Text Revision The effort to revise the DSM-N text was also a team effort. We are especially in- debted to the tireless efforts of the DSM-N Text Revision Work Groups (listed on pp. X'V- xvii), who did the lion's share of the work in the preparation of this revision. We w ouJd also like to acknm·vledge the contribution of the various advisers to the Work Groups (see Appendix K, p . 929), w ho provided their perspective on w hether the proposed changes were justified. Finally, we wouJd like to thank the American Psychiatric Association's Committee on Psychia h;c Diagnosis and Assessment (listed on p . xvii), wh o provided helpful guidance and oversight during the p rocess as ·well as approval of the final document. Special gratitude goes to committee members Katharine A. Phillips and Janet B. W. Williams, for their meticulously carefuJ review of the text revision. OJ course, none of Ulis could have happened without the invalu- able organizational and administrative assistance provided by the DSM-IV staff, 1.-aurie McQueen and Yoshie Satake, and production assistance provided by Anne Barnes, Pam Harley, Greg Kuny, Claire Reinbmg, and Ron McMillen at Amer ican Psychiatric Press. Michael B. First, M.D. Co-Cimirperson n11d Editor Harold Alan Pincus, M.D. Co-Clznirpersou • XXI •
  • 16. Introduction his is the fourth edition of the American Psychiatric Association's Diagnostic and Statistical Mmwal of Mental Disorders, or DS1vl-IV. The utility and credibility of DSM-IV require that it focus on its dinical, reseru·ch, and edu cational purposes and be support· ed by an extensive empirical foundation. Our highest priority has been to provide a helpful guide to clinical practice. We h oped to make DSM-IV p ractical and useful for clinician s by striving for brevity of criteria sets, clarity of language, and explicit state- ments of the constructs ernbodjed in the diagnostic criteria. An additional goal was to facilitate research and improve communication among clinicians and researchers. We were also mindful of the use of DSM-IV for improving the collection of clinical infor- mation and as an educational tool for teaching p sychopathology. An official nomenclature must be applicable in a wide diversity of contexts. DSM-IV is used by clinicians and researchers of many different orientations (e.g., biological, psychod)marnic, cognitive, behavioral, interpersonal, family/ systems). It is used by psychiatrists, other physicians, psychologists, social workers, nurses, occupational and rehabilitation therapists, counselors, and other h ealth and mental health profession- als. DSM-IV mus t be usable across settings-inpatient, outpatient, partial hospital, consultation-liaison, clinic, private practice, and primary care, and with community populations. It is also a necessary tool for collecting and commwucating accurate public health s tatistics. Fortunately, all these m any uses are compatible with one another. n, DSM-lV was the product of 13 Work Groups (see Appendix each of which had primary responsibility for a section of the manual Tllis organization was designed to increase participation by experts in each of the respective fields. We took a number of precautions to ensure that the vVork Group recommendations would reflect the breadth of available evidence and opinion and n ot just the views of the specific mem- bers. After e-xtensive consultations with experts and clliticians in eacl1 field, we select- ed Work Group members who represented a wide range of perspectives and experiences. -fork Group members were instructed that they were to participate as consensus scholars and not as advocates of previously held vie~ws . Furthermore, we established a formal evidence-based process for the Work Groups to fo11ow. The Work Groups reported to the Task Force on DSM-IV (see p. xi), which consist- ed of 27 members, many of vhom also cl1aired a Work Group. Each of the 13 vVork Groups was composed of 5 (or more) members whose reviews were critiqued by between 50 and 100 advisers, who vvere also cl10sen to represent diverse clinical and research expertise, disciplines, backgrounds, and settings. The involvement of many international experts ensured that DSM-JV had ava.i lable the widest pool of informa- tion and would be applicable across cultures. Conferences and workshops were held to provide conceptual and methodological guidance for the DSM-IV effort. These -·· XXIII
  • 17. I xxiv Introduction included a number of consultations between the developers of DSM-IV and the de- velopers of ICD-10 conducted for the purpose of increasing compatibility between the two systems. Also held were methods conferences that focused on culrural factors in the diagnosis of mental disorder, on geriatric diagnosis, and on psychiatric diag- nos is in primary care settings. To maintain open and extensive lines of communication, the Task Force on DSM-IV established a liaison with many other components within the American Psycluatric Association and with more than 60 organizations and associations interested in the development of DSM-IV (e.g., American Health Information Management Associa- tion, American Nurses' Association, Am.erican Occupational Therapy Association, American Psychoanalytic Association, American Psychological Association, Ameri- can Psychological Society, Coalition for the Family, Group for the Advancement of Psycl1iatry, N ational Association of Social Workers, National Center for H ealth Sta- tistics, World Health Organization ). We attempted to air issues and empirical evi- dence early in the process in order to identify potential problems and differences in interpretation. Excl1anges of information were also made poss ible through the distri- bution of a semiannual n ewsletter (the DSM-IV Update), the publication of a regular column on DSM-IV in Hospital a11d ConummihJ PSljchiatn;, frequent presentations at national and intemational conferences, and numerous journal articles. Two years before the publication of DSM-IV, the Tas k Force published and wi dely distributed the DSM-W Oplious Book. This volume presented a comprehensive sum- mary of the alternative proposals that were being considered for inclusion in DSM-IV in order to solicit opinion and additional data for our deliberations. W e received ex- te ns ive correspondence from interested individuals who shared v.rith us additional data and recommendations on the potential impact of the possible changes in DSM-fV on their clinical practice, teaching, research, and administrative work. Tlus breadth of discussion helped us to anticipate problems and to attempt to find the best solution among the various options. One year before the publication of DSNf-IV, a near-final draft of the proposed criteria sets was distributed to allow for one last critique. In arriving at final DSM-IV decisions, the Work Groups and the Task Force re- viewed all of the extensive empirical evidence and correspondence that had been gathered. It is our belief that the major innovation ofDSM-IV lies not in any of its spe- cific content changes but rather in the systematic and explicit process b y wlucl1. it was constructed and documented. More than any oth er nomenclature of mental disor- ders, DSM-IV is grounded in empirical evidence. Historical Background The need for a classification of mental disorders has been clear throughout the history of medicine, but there has been little agreement on which disorders should be includ- ed and the optimal method for their organization. The many nomenclahlres that have been developed during the past hvo millennia have differed in their relative empha- sis on phenomenology, etiology, and course as defining features. Some systems h ave included only a handful of diagnostic categories; o thers have included thousands. Moreover, the various systems for categorizin g mental disorders have differed with respect to whether their principle objective vas for use in clinical, research, or statis- tical settings. Because the history of classification is too extensive to be summarized
  • 18. Introduction .xxix I fourth volume contains reports of the data reanalyses, reports of the field trials, and a final executive summary of the rationale for the decisions made by each. Work Group. Tn addition, many papers were stimulated by the efforts toward empirical d ocumentation in DSM-N, and these have been published in peer-reriewed journals. Relation to ICD-10 Tile tenth revision of the l11tematio11al Statistical Classiftcntioll of Diseases and Related Health Problems (ICD-10), developed by WHO, was published in 1992. A clinical mod- ification of ICD-10 (ICD-10-CM) is expected to be implemented in the United States in 2004. Those preparing [CO-l 0 and DSM-IV have worked closely to coordinate their efforts, res ulting in much mutual influence. ICD-10 consists of an official coding sys- tem and other related clinical and research documents and ins truments. The codes and terms provided in DSM-N are fully compatible w ith both ICD-9-CM and ICD-10 (see Appendix H). The clinical and research drafts of ICD-10 were thoroughly re- v iewed by the DSNf-N Work Groups and suggested important topics for DSM-IV lit- erature reviews and data reanalyses. Draft versions of the ICD-10 Diagnostic Criteria for Research were included as alternatives to be compared with DSM-ID, DSM-ill-R, and suggested DSM-IV criteria sets in the DSM-IV field trials. The many consul- tations behveen the developers of DSM-IV and ICD-10 (which were facilitated by NIMH, NIDA, and NIAAA) were enormously useful in increasing the congruence and reducing meaningless differences in wording between the hvo systems. The DSM-IV Text Revision One of the m ost important uses of DSM-IV has been as an educational tool. This is especially true of the descriptive text that accompanies the criteria sets for DSM-IV disorders. Given that the interval beh'een DSM-IV and DSM-V is being extended relative to the intervals behveen earlier editions (from 7 years beh,•een DSM-ill and DSM-ill-R and behveen DSM-ill-R and DSM-IV, to at least 12 years), the infom1ation in the text (which was prepared on the basis of literature dating up to 1992) runs the risk of becoming inueasingly out-of-pace -.. -.rith the large volume of research pub- lis hed ead'l year. In order to bridge the span between DSM-IV and DSM-V, a revision of the DSM-IV text was undertaken. The goals of this text revision were severalfold: 1) to correct any factual errors that were identified in the DSM-IV text; 2) to review the DSM-IV text to ensure that all of the information is still up-to-date; 3) to make changes to the DSM-IV text to reflect new information a·ailable since the DSM-IV lit- erature reviews ·were completed in 1992; 4) to make improve:men ts that will enhance the educational v alue of DSM-IV; and 5) to update those ICD-9-CM codes that were changed since the DSM-IV 1996 Coding Update. As with the original DSM-IV, all changes proposed for the text had to be supported by empirical data. Furthermore, all proposed changes 'vere limited to the text sections (e.g., Associated Features and Disorders, Prevalence). No s ubs tantive changes in the criteria sets were considered, nor were any proposals entertained for new disorders, new s ubtypes, or changes in the statu s of the DSM-IV appendix categories. The text revision process began in 1997 with the appoinbnent of DSM-IV Text Re- vision Work Groups, correspon ding to the original DSM-IV Work Group structure.
  • 19. Introduction XXV I here, v,re focus briefly only on those aspects that have led directly to the development of the Diagnostic and Statistical Manual of Me11tal Disorders (DSM) and to the "Mental Disorders" sections in the various editions of the International Classification of Diseases (ICD). In the United States, the initial impetus for developing a classification of mental disorders ·w as the need to collect statistical infom1ati.on. What might be considered the first official attempt to gather infom1ation about mental illness in the United States was the recording of the frequency of one category- "idiocy/ insanity" in the 1840 census. By the 1880 census, seven categories of mental illness w ere distin- guished- mania, melancholia, monomania, paresis, dementia, dipsomania, and epi- lepsy. In 1917, the Committee on Statistics of the American Psychiatric Association (at that time called the American Medico-Psychological Association [the name was changed in 1921]), together with the National Commission on Mental H ygiene, for- mulated a plan that was adopted by the Bureau of the Censu s for gathering wliform statistics across mental hospitals. Although this system devoted more attention to clinical utility than did previous systems, it was still primarily a statistical classifica- tion. The American Psychiatric Association subsequently collaborated with the New York Academy of Medicine to develop a nationally acceptable psychiatric nomen- clature that vould be incorporated within the first edition of the American Medical Association's Standard Classified Nomenclature of Disease. This nomenclature was designed primarily for diagnosing inpatients w ith severe psychiatric and neurologi- cal d isorders. A much broader nomenclature was later developed by the U.S. Army (and modi- fied b y the Veterans Administration) in order to better incorporate the outpatient pre- sentations of World War II servicemen and veterans (e.g., psychophysiological, personality, and acute disorders). Contemporaneously, the World Health Organi- zation (WHO) published the sixth edition of ICD, which, for the first time, included a section for mental disorders. ICD-6 ·was heavily influenced by the Veterans Admin- istration nomenclature and included 10 categories for psychoses, 9 for psychoneuro- ses, and 7 for disorders of character, behavior, and inteljjgence. The American Psychiatric Association Committee on -omenclature and Statistics developed a variant of the ICD-6 that was published in 1952 as the first edition of the Ding11ostic a11d Statistical Manual: Mental Disorders (DSM-I). DSM-I contained a glossa- ry of descriptions of the diagnostic categories and w'as the first official manual of mental disorders to focus on clinical utility. The use of the term reaction throughout DSM-1 reflected the influence of Adolf Meyer's psychobiological view that mental disorders represented reactions of the personality to psychological, social, and bio- logical factors. In part because of the lack of · idespread acceptance of the mental disorder taxon- w omy contained in ICD-6 and ICD-7, WHO sponsored a comprehensive review of diagnostic issues that was conducted by the British psychiahist StengeL His report can be credited with having inspired many of the recent advances in diagnostic meth- odology- most especially the need for ex-plicit definitions as a means of promoting reliable clinical diagnoses. However, the next round of diagnostic revision, whid1led to DSM-ll and ICD-8, did not follow Stengel's recommendations to any great degree. DSM-ll v.ras similar to DSM-I but eliminated the term t·eaction. As had been the case for DSM-I and DSM-IT, the development of DSlvl-III was co-
  • 20. I xxvi Introdu ction ordinated with the development of the next (ninth) version of ICD, which was pub- lished in 1975 and implemented in 1978. Work began on DSM-III in 1974, with publication in 1980. DSM-III introduced a number of important methodological inno- vations, including explicit diagnostic criteria, a multiaxial system, and a descriptive approach that attempted to be neutral with respect to theories of etiology. This effort was facilitated by the extensive empirical v.rork then under way on the construction and validation of explicit diagnostic criteria and the development of semistructured inten~iews. ICD-9 did not include diagnostic criteria or a multiaxial system largely because the primary function of this intemational system was to delineate categories to facilitate the collection of basic health statistics. In contrast, DSlvl-III was developed with the additional goal of providing a medical nomenclature for clinicians andre- seardlers. Because of dissatisfaction across all of medicine with the lack of specificity in ICD-9, a decision was made to modify it for use in the United States, resulting in ICD-9-CM (for Clinical Modification). Experience with DSM-ill revealed a number of inconsistencies in the system and a number of instances in which the criteria were not entirely clear. Therefore, the Amer- ican Psychiatric Association appointed a Work Group to Revise DSM-III, which de- veloped the revisions and corrections that led to the publication of DSM-III-R in 1987. The DSM-IV Revision Process The third edition of the Diagnostic and Stntisticallvimwal of Mental Disorders (DSM-III) represented a major advance in the diagnosis of mental disorders and greatly faci1i- tated empirical research. The development of DSM-IV has benefited from the s ub- stantial increase in the research on diagnosis that was generated in part by DSM-III and DSM-III-R. Most diagnoses now have an empirical literature or available data sets that are relevant to decisions regarding the revision of the diagnostic manual. The Task Force on DSM-IV and its Work Groups conducted a three-stage empirical process that included 1) comprehensive and systematic reviews of the published lit- erature, 2) reanalyses of already-collected data sets, and 3) extensive issue-focused field tria Is. Literature Reviews Two methods conferences were sponsored to articulate for all the Work Groups a sys- tematic procedure for finding, extracting, aggregating, and interpreting data in a comprehensive and objective fashion. The initial tasks of each of the DSM-IV Work Groups were to identify the most pertinent issues regarding each diagnosis and to de- termine the kinds of empirical data relevant to their resolution. A Work Group mem- ber or adviser was then assigned the responsibility of conducting a systematic and comprehensive review of tl1e relevant literature that would inform the resolution of the issue and also document the text of DSM-IV. The domains considered in making decisions included clinical utility, reliability, descriptive validity, psychometric per- formance characteristics of individual criteria, and a number of validating variables. Eadlliterature review specified 1) the issues or aspects of the text and criteria un- der consideration and the significance of the issues '"~th respect to DSM-IV; 2) there- view method (including the sources for identifying rele,·ant studies, the number of
  • 21. Introd uction xxvii studies considered, the criteria for inclu sion and exclusion from the review, and the variables catalogued in each study); 3) the results of the review (including a descrip- tive summary of the studies with respect to methodology, design, and substantive correlates of the findings, the relevant findings, and the analyses conducted on these findings); and 4) the various options for resolving the issue, the advantages and dis- advantages of each option, recommendations, and suggestions for additional re- search that would be needed to provide a more concJusive resolution. The goal of the DSM-IV literature reviews was to provide comprehensive and un- biased information and to ensure that DSM-IV reflects the best available cJinical and research literature. For this reason, we used systematic computer searches and critical reviews done by large groups of advisers to ensure Hlat the literahue coverage -vas adequate and that the interpretation of the results was justified. Input was solicited especially from those persons likely to be critical of the conclusions of the review. ll1e literature reviews were revised many times to produce as comprehensive and bal- anced a result as possible. It must be noted that for some issues addressed by the DSM-IV Work Groups, particularly those that were more conceptual in nature or for which there were insufficient data, a review of the empirical literature had limited utility. Despite these limitations, the reviews were helpful in documenting the ratio- nale and empirical support for decisions made by the DS!vf-IV Work Groups. Data Reanalyses When a review of the literature revealed a lack of evidence (or conflicting evidence) for the resolution of an issue, we often made use of two additional resources-data reanalyses and field trials-to help in making final decisions. Analyses of relevant unpublished data sets were supported b y a grant to the American Psychiatric Asso- ciation from the John D. and Catherine T. MacArthur foundation. Most of the -!0 data reanalyses performed for DSM-IV involved the collaboration of several investigators at different sites. These researchers jointly subjected their data to questions posed by the Work Groups concerning the criteria included in DSM-ill-R or criteria that might be included in DSM-IV. Data reanalyses also made i t possible for Work Groups to generate several criteria sets that were then tested in the DSM-IV field trials. Al- though, for the most part, the data sets used in the reanalyses had been coJJected as part of epidemiological studies or treatment or other clinical studies, they were also highly relevant to the nosological questions facing the DSM-IV Work Groups. Field Trials Twelve DSM-IV field trials were sponsored by the National Institute of Mental Health (NThtlli) in collaboration with the Nationallnstitute on Drug Abuse ( ITDA) and the National Institute on Alcohol Abuse and Alcoholism {NIAAA). The field tri- als allowed the DSM-IV Work Groups to compare altemative options and to study the possible impact of suggested changes. Field trials compared DSM-III, DSM-III-R, ICD-10, and proposed DSM-IV criteria sets in 5-10 different sites per field trial, v.•ith approximately 100 subjects at each site. Diverse sites, with representative groups of subjects from a range of socioculhual and ethnic backgrounds, ·w ere selected to en- snre generaJizability of field-trial results and to test some of the most difficult ques-
  • 22. I xxviii Introduction tions in differential ctiagnosis. The 12 field trials included more than 70 sites and evaluated more than 6,000 subjects. The field trials collected information on the reli- ability and performance cl1aracteristics of each criteria set as a whole, as ~well as of the specific items within each criteria set. The field trials also helped to bridge the bound- ary between clinical researcl1 and clinical practice by determining how well sugges- tions for change that are derived from clinical research findings apply in clinical practice. Criteria for Change Although it 1vas impossible to develop absolute and infallible criteria for when cl1anges should be made, there were some principles that guided om efforts. The threshold for making revisions in DSM-IV was set higher than that for DSM-ffi and DSM-ill-R. Deci- sions had to be substantiated by explicit statements of rationale and by the systematic re- view of relevant empirical data. To increase the practicality and clinical utility of DSM-IV, the criteria sets were simplified and clarified when this could be justified by empirical data. An attempt was made to strike an optimal balance in DSM-IV with respect to his- torical tradition (as embodied in DSM-ill and DSM-ID-R), compatibility with ICD-10, evidence from rev iews of the literature, analyses of unpublished data sets, results of field trials, and consensus of the field . Although the amount of evidence required to support changes >vas set at a high thresho1d, it necessarily varied across disorders because the empirical support for the decisions made in DSM-ID and DSM-ID-R also varied across disorders. Of comse, common sense was necessary, and major changes to solve minor problems required more evidence than minor changes to solve major problems. We received suggestions to include numerous new diagnoses in DSM-IV. The pro- ponents argued that the new diagnoses were necessary to improve the coverage of the system by including a group of individuals that vere undiagnosable in DSM-ill-R or diagnosable only under the . Jot Otherwise Specified rubric. We decided that, in general, n ew diagnoses should be included in the system only after research has es- tablished that they should be included rather than being included to s timulate that researcl1. However, diagnoses already included in ICD-10 were given somewhat more consideration than those that were being proposed fresh for DSM-IV. The in- creased marginal utility, clarity, and coveTage provided by each newly proposed di- agnosis had to be balanced against the cumulative cumbersomeness imposed on the 'vhole system, the paucity of en1pirical documentation, and the possible misdiagnosis or misuse that might result. No classification of mental disorders can have a sufficient number of specific categories to encompass every conceivable clinical presentation. The -ot Otherwise Specified categories are provided to cover the not infrequent pre- sentations that are at the boundary of specific categorical definitions. The DSM-/V Sourcebook Documentation has been the e...c:sential foundation of the DSM-IV process. The DSM-N Sourcebook, published in four volumes, is intended to provide a comprehensive and convenient reference record of the clinical and researd1 support for the v arious deci- sions reached by the Work Groups and the Task Force. The first three volumes of the Sourcebook contain condensed versions of the 150 DSM-IV literature reviews. The
  • 23. lxxx Introduction The chairs of the original DSM-IV Work Groups were consulted first regarding the composition of these Text Revision Work Groups. Each Text Revision Work Group was given primary responsibility for updating a section of the DSM-IV text. This en- tailed reviewing the text carefully to identify errors or omissions and then conducting a systematic, comprehensive literature review that focused on relevant material that has been published since 1992. Text Revision Work Group members then drafted pro- posed changes, which w ere accompanied by written justifications for the changes alon g with relevant references. During a series of conference caUs, the proposed changes, justifications, and references ·were presented by a Text Revision Work Group member to other members of the Text Revision Work Group, who provided input regarding whether the changes were justified on the basis of the supporting documentation. Once c.i?a.fts of the proposed changes were finalized by the Text Re- vision Work Groups, the changes were more widely disseminated to a group of sec- tion-specific advisers (consisting of the original DSM-IV Work Group members supplemented by additional consultants) for further comment and review. These ad- visers were also given the opporhmity to suggest additional changes if they could provide sufficient convincing evidence justifying inclusion in the text. After consid- eration of the adviser comments, final drafts of proposed changes were produced and submitted for final review and approval by the American Psychiatric Association's Committee on Psychiatric Diagnosis and Assessment. Most of the proposed literature-based changes were in the Associated Features and Disorders (which includes Associated Laboratory Findings); Specific Culhue, Age, and Gender Features; Prevalence; Course; and Familial Pattern sections of the text. For a number of disorders, the Differential Diagnosis section also was expanded to provide more comprehensive differentials. Appen dix D (seep. 829) provides an overview of the changes included in this text revision. Definition of Mental Disorder Although this volume is titled the Diag11ostic and Statistical Mmmal of Mental Disorders, the term mental disorder unfortunately implies a distinction between "mental" dis- orders and "physical" disorders that is a reduction:istic anachronism of mind / body dualism. A compelling literahll'e documents that there is much "ph ysical" in "men- tal" disorders and much "menta l" in "physical" disorders. TI1e problem raised by the term "mental" disorders has been much clearer than its solution, and, unfortunately, the term persists in the title of DSM-IV because we have not found an appropriate substitute. Moreover, although this manual provides a classification of mental disorders, it must be admitted that no definition adequately specifi.es precise boundaries for the concept of "me11tal disorder." The concept of m ental disorder, like many other con- cepts in medicine and science, lacks a consistent operational definition that covers all situations. All medical conditions are defined on various levels of abstraction- for example, stn1chll'al pathology (e.g., ulcerative colitis), symptom presentation (e.g., migraine), deviance from a physiological norm (e.g., hypertension), and etiology (e.g., pneumococcal pnemnonia). Mental disorders have also been defined by a vari- ety of concepts (e.g., distress, dysfunction, dyscontrol, disadvantage, disability, in- flexibility, irrationality, syndromal pattern, etiology, and statistical deviation). Each
  • 24. Introduction xxxi is a useful indicator for a mental disorder, but none is equivalent to the concept, and dillerent situations caJJ for dillerent definitions. Despite these caveats, the definition of mental disorder that was included in OSM-m and OSM-lll-R is presented here because it is as useful as any other available defini- tion and has helped to guide decisions regarding which conditions on the boundary between normality and pathology s hould be included in DSM-IV. In DSM-IV, each of the mental disorders is conceptualized as a clinically significant behavioral or psy- chological syndrome or pattern that occurs in an individual and that is associated v.rith present distress (e.g., a painful symptom) or disability (i.e., ilnpaim1ent in one or more ilnportant areas of functioning) or with a significantly increased risk of suf- fering death, pain, disability, or an important loss of freedom. In addition, this syn- drome or pattern must not be merely an expectable and culturally sanctioned response to a particular event, for example, the d eath of a loved one. Vvhatever its original cause, it must currently be considered a manifestation of a behavioral, psycho- logical, or biological dysfunction in the individual. Neither deviant behavior (e.g., po- litical, religious, or sexual) nor conflicts that are primarily between the individual and sodety are mental disorders unless the deviance or conflict is a symptom of a dysfunc- tion in the indh·i dual, as described above. A common misconception is that a classification of mental disorders classifies peo- ple, when actually what are being classified are disorders that people have. For this reason, the text of DSM-IV (as did the text of DSM-ill-R) avoids the use of such ex- pressions as "a schizophrenic" or "an alcoholic" and instead uses the more accurate, but admittedly more cumbersome, "an individual with Schizophrenia" or "an indi- vidual with Alcohol Dependence." Issues in the Use of DSM-IV Limit ations of t he Categorica l Appro ach DSM-N is a categorical classification that dirides mental disorders into types based on criteria sets with defining features. This naming of categories is the traditional method of organizing and transmitting information in ezeryday life and has been the fundamental approacl1 used mall systems of medical diagnosis. A categorical ap- proach to classification works best w hen all members of a diagnostic class are homo- geneous, when there are clear boundaries between classes, and when the different classes are mutually exclusive. Nonetheless, the limitations of the categorical classifi- cation system must be recognized. ln DSM-IV, there is no assumption that each category of mental disorder is a com- pletely discrete entity with absolute boundaries dividing it from other mental dis- orders or from no mental disorder. There is also no assumption that all individuals desoibedas having the same mental disorder are alike in all important ways. The cli- nician using DSlvl-lV should therefore consider that mdividuals sharing a diagnosis are likely to be heterogeneous even in regard to the defining features of the diagnosis and that boundary cases will be difficult to diagnose in any but a probabilistic fash- ion. This outlook allows greater flexibility in the use of the system, encourages more specific attention to boundary cases, and emphasizes the need to capture additional
  • 25. I xxxii Introd uction clinical information that goes beyond ctiagnosis. In recognition of the heterogeneity of clinical presentations, DSM-IV often includes polythetic criteria sets, in which the individual need only present with a subset of items from a longer list (e.g., the diag- nosis of Borderline Personality Disorder requires only five out of nine items). It was suggested that the DSM-lV Classification be organized following a dimen- sional model rather than the categorical model used in DSM-TTI-R. A dimensional sys- tem classifies clinical presentations based on quantification of attributes rather than the assignment to categories and VOrks best in describing phenomena that are dis- tributed continuously and that do not have clear boundaries. Although dimensional systems increase reliability and communicate more clinical information (because they report clinicalattrip~tes that might be subthreshold in a categorical system), they also have serious limitations and thus far have been less usefuJ than categorical systems in clinical practice and in stimulating researd1. Numerical dimensional descriptions are much less familiar and vivid than are the categorical names for menta] disorders. Moreover, there is as yet no agreement on the choice of the optimal dimensions to be used for classification purposes. Nonetheless, it is possible that the increasing re- search on, and familiarity with, dimensional systems may eventually result in their greater acceptance both as a method of conveying clinical information and as are- search tool. Use of Clinical Judgment DSM-JV is a classification of mental disorders that was developed for use in clinical, educational, and research settings. The diagnostic categories, oiteria, and textual de- scriptions are meant to be employed by individuals with appropriate clinical training and experience in diagnosis. It is important that DSM-JV not be applied mechanically by untrained individuals. The specific diagnostic criteria included in DSM-IV are mea11t to serve as guidelines to be informed by clinical judgment and are not meant to be used in a cookbook fashion. For example, the exercise of clinical judgment may justify giving a certain diagnosis to an individual even though the clinical presenta- tion falls just short of meeting the full criteria for the diagnosis as long as the symp- toms that are present are persistent and severe. On the other hand, Jack of familiarity with DSM-IV or excessively flexible and idiosyncratic applkation of DSM-IV criteria or conventions substantially reduces its utility as a common language for communi- cation. Ln addition to the need for clinical training and judgment, the method of data col- lection is also important. The valid application of the diagnostic criteria included in this manual necessitates an evaluation that directly accesses the information con- tained in the criteria sets (e.g., whether a syndrome has persisted for a minimum pe- riod of time). Assessments that rely solely on psychological testing not covering the criteria content (e.g., projective testing) cannot be validly used as the primary source of diagnostic infom1ation. Use of DSM-IV in Forensic Settings When the DSM-IV categories, criteria, and textual descriptions are employed for forensic purposes, there are significant risks that diagnostic information will be rnis-
  • 26. • Introduction xxxiii I used or misunderstood. These dangers arise because of the imperfect fit between the questions of ultimate concern to the law and the information contained in a clinical diagnosis. In most situations, the clinical diagnosis of a DSM-IV mental disorder is not sufficient to establish the existence for legal purposes of a "mental disorder/' "mental disability," "m ental disease," or "mental defect ." In determining whether an individual meets a specified legal standard (e.g., for competen ce, criminal resp onsi- bility, or disability), additional information is usually required beyond that contained in the DSM-lV d iagnosis. This m ight include information about the individual's func- tional impairments and h ow these impairments affect the particular abil ities in ques- tion. Itis precisely because impairments, abilities, and disabilities vary widely within each diagnostic category that assignment of a particular diagnosis does not imply a specific level of impairment or disability. Nonclinical decision makers should also be cautioned that a diagnosis d oes not carry any n ecessary implications regarding the causes of t he individual's mental dis- order or its associated impaim1ents.lnclusion of a disorder in the Classification (as in medicine generally) does not require that there be knowledge about its etiology. Moreover, the fact that an individual's p resentation meets the criteria for a DSM-IV diagnosis does not carry any necessary implication regard ing the individual's degree of control over the behaviors that may be associated with the disorder. Even when di- minished control over one's behavior is a feature of the disorder, having the diagnosis in itself does not demonstrate tha t a particular individual is (or was) unable to control his or her behavior at a particular time. Tt must be noted that DSM-lV reflects a consensus about the classification and di- agnosis of mental disorders derived at the time of its initial p ublication. New knowl- edge generated by research or clinical exrperience will undoubtedly lead to an increased understanding of the disorders included in DSM-IV, to the identification of new disorders, and to the removal of some disorders in future classifications. The text and criteria sets included in DSM-IV will require reconsideration in light of evolving new infom1ation. The u se of DSM-IV in forensic settings should be informed by an awareness of the risks and limitations discussed above. When used appropriately, diagnoses and diag- nostic information can assist decision makers in their d eterminations. For example, when the presence of a m ental disor der is ·the predicate for a s ubsequent legal d eter- mination (e.g., involuntary civil commitment), the use of--an-established system of diagnosis enhances the value and reliability of the determination . By providing a com- pendium based on a review of the pertinent clinical and research litera ture, DSM-IV may fadlita te the legal decision makers' understanding of the relevant characteristics of mental disorders. The literature related to diagnoses also serves as a check on un- grounded speculation about mental disorders and about the functioning of a partic- ular individual. Finally, diagnostic information regarding longitudinal course may improve decis ion making when the legal issue concerns an individual's mental func- tioning at a p ast or future point in time. Ethnic and Cultural Considerations Special efforts have been made in the preparation of DSM-TV to incorporate an aware- ness that the manual is used in culturally diverse populations in the United States and
  • 27. I xxxiv Introduction internationally. Clinicians are called on to evaluate individuals from numerous dif- ferent ethnic groups and cultural backgrounds (including many w ho are recent im- migrants). Diagnostic assessment can be especially challenging ·wh en a clinician from one ethnic or cultural group uses the DSM-IV Oassification to evaluate an individual from a different ethnic or cultural group. A clinician w h o is unfamiliar with the nu- ances of an individual's cultural frame of reference may incorrectly judge as psycho- pathology those normal variations in behavior, belief, or experience that are particular to the individual 's culture. For example, certain religious practices or be- liefs (e.g., hearing or seeing a deceased relative during bereavement) may be misdi- agnosed as manifestations of a Psychotic Disorder. Applying Personality Disorder criteria across cultttr~ settings may be especially difficult because of the wide cultur- al variation in concepts of self, styles of communication, and coping m echanisms. DSM-IV includes three types of information specifically related to cultural consid- erations: 1) a discussion in the text of cultural variations in the clinical presentations of those disorders that h ave been included in the DSM-IV Classification; 2) a descrip- tion of culture-bound syndromes that have not been included in the DSM-IV Classi- fication (these are included in Appendix I); and 3) an outline for cultural fomllllation designed to assis t the clinician in systematically evaluating and reporting the impact of the individual's cultural context (also in Appendix I). The wide international acceptance of DSM s ugges ts that this classification is useful in describing mental disorders as they are experienced by individuals throughout the world. Nonetheless, evidence also suggests that the symptoms and course of anum- ber ofDSM-IV disorders are influenced by cultural and ethnic factors. To facilitate its application to individuals from diverse cultural and ethnic settings, DSM-IV includes a new section in the text to cover culture-related features. 1ltis section describes the ways in 'vhich varied cultural backgrounds affect the content and form of the symp- tom presentation (e .g., depressive disorders characterized by a preponderance of so- matic symptoms rather than sadness in certain culhues), preferred idioms for describing distress, and information on prevalence ,., hen it is available. The second type of cultural information provided pertains to "culture-bound S)rn- dromes'' that have been described in just one, or a few, of the world's societies. DSM-IV provides hvo ways of increasing the recognition of culture-bound syndromes: 1) some (e.g., amok, ataque de nervios) are included as separate examples in Not Otherwise Specified categories; and 2) an appendix of culture-bound syndromes (Appendix I) has been introduced in DSM-IV that includes the name for the condition, the cultures in which it was first described, and a brief description of the p sychopathology. The provision of a culture-specific section in the DSM-IV text, the inclusion of a glossary of culture-bound syndrom es, and the provision of an outline for cultural for- mulation are designed to enhance the cross-cultural applicability of DSM-IV. It is hoped that these new features will increase sensitivity to variations in how mental disorders may be expressed in d ifferent cultures and will reduce the possible effect of unintended b ias stemming from the clinician's mvn cultural background. Use of DSM-IV in Treatment Planning Making a DSM-IV diagnosis is only the first step in a comprehensive evaluation. To formulate an adequate treatment plan, the clinician v.rilJ. invariably require consider-
  • 28. Introduction XXXV able additional information about the person being evaluated beyond that required to make a DSM-IV diagnosis. Distinction Between Mental Disorder and General Medical Condition The terms mental disordeJ" and gellernl medicnl condition are used throughout this man- ual The term me11tnl disorder is explained above. The term general medical co11ditio11 is used merely as a convenient shorthand to refer to conditions and disorders that are listed outside the '1Y1ental and Behavioural Disorders" chapter of ICD. It should be recognized that these are merely terms of convenience and should not be taken to im- p ly that there is any fundamental distinction behveen mental disorders and general medical conditions, that mental disorders are unrelated to physical or biological fac- tors or processes, or that general medicaJ conditions are unrelated to behavioral or psychosocial factors or processes. Organization of the Manual The manual begins with instructions concerning the use of the manual (p. 1), followed by the DSM-IV-TR Classification (pp. 13-26), which provides a systematic listing of the official codes and categories. Next is a description of the DStvl-IV Multiaxial Sys- tem for assessment (pp. 27-37). This is followed by the diagnostic criteria for each of the DSM-IV d isorders accompanied by descriptiv e text (pp. 39-743). Finally, DSM-N includes 11 appendixes.
  • 29. Cautionary Statement he specified diagnostic criteria for each mental disorder are offered as guidelines ior making diagnoses, because it has been demonstrated that the use of such criteria enhances agreement among clinicians and investigators. The proper use of these cri- teria requires specialized clinical training that provides both a body of knowledge and clinical skills . These diagnostic criteria and ·the DSM-rv Classification of m ental disorders reflect a consensus of current formulations of evolving knowledge in our field . They do not encompass, however, all the conditions for which people may be treated or that may be appropriate topics for research efforts. The purpose of DSM-N is to provide clear descriptions of diagnostic categories in order to enable clinicians and investigators to diagnose, communicate about, study, and treat people with v arious mental disorders. It is to be understood that inclusion here, for clinical and research purposes, of a diagnos tic category such as Pathological Gambling or Pedophilia does not imply that the condition meets legal or other non- medical criteria for what constitutes mental disease, mental disorder, or mental dis- ability. The clinical and scientific considerations involved in categorization of these conditions as mental disorders may not be wholly relevant to legal judgments, for example, that take into account such issues as individual responsibility, disability determination, and competency. •• XXXVII I
  • 30. Use of the Manual Coding and Reporting Procedures Diagnostic Codes The official coding system in use in the United States as of publication of thjs manual is the l11tematiollal Classifimtion of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM). Most DSM-IV disorders have a numerical ICD-9-CM code that appears several times: 1) preceding the name of the disorder in the Classification (pp. 13-26), 2) at the beginning of the text section for each disorder, and 3) accompanying the cri- teria set for each disorder. For some diagnoses (e.g., Mental Retardation, Substance- Induced Mood Disorder), the appropriate code depends on further specification and is listed after the text and criteria set for the disorder. The names of some djsorders are followed by alternative terms enclosed in parentheses, which, in most cases, were the DSM-ID-R names for the disorders. The use of diagnostic codes is fundamental to medical record keeping. Diagnostic coding facilitates data collection and retrieval and compilation of statistical informa- tion. Codes also are often required to report diagnostic data to interested third parties, including governmental agencies, private insurers, and the World Health Organiza- tion. For example, in the United States, the use of these codes has been mandated by the Health Care Financing Administration for purposes of reimbursement under the Medicare system. Subtypes (some of which are coded in the fifth digit) and specifiers are provided for increased specificity. Subh;pes define mutually exclusive and jointly exhaustive phenomenological subgroupings within a diagnosis and are indicated by the instruc- tion "specify type" in the criteria set. For example, Del.i.~s ional Disorder is subtyped based on the content of the delusions, with seven subtypes provided: Erotomanic Type, Grandiose Type, Jealous Type, Persecutory Type, Somatic Type, lvlixed Type, and Unspecified Type. ln contrast, specifiers are not intended to be mutually exclusive or jointly exhaustive and are indicated by the instruction "specify" or "specify if" in the criteria set (e.g., for Social Phobia, the instruction notes "Specify if: Generalized"). Specifiers provide an opportunity to define a more homogeneous subgrouping of individuals with the disorder who share certain features (e.g., Major Depressive Dis- order, With Melancholic Features). Although a fifth digit is sometimes assigned to code a subtype or specifier (e.g., 294.11 Dementia of the Alzheimer's Type, With l.ate Onset, With Behavioral Disturbance) or severity (296.21 Major Depressive Disorder, Single Episode, Mild), the majority of subtypes and specifiers included in DSM-IV cannot be coded w ithin the ICD-9-CM system and are indicated only by including the subtype or specifier after the name of the disorder (e.g., Social Phobia, Generalized). 1
  • 31. 2 Use of the Manual Severity and Course Specifiers A DSM-N diagnosis is usually applied to the individual's current presentation and is not typically used to denote previous diagnoses from v.rhich the individual has recov- ered. The following specifiers indicating severity and course may be listed after the diagnosis : Mild, Moderate, Severe, In Partial Remission, In Full Remission, and Prior His tory. The sp ecifi ers Mild, Moderate, and Severe should be used only when the full cri- teria for the disorder are currently met. In deciding whether the presentation should be described as mild, moderate, or severe, the clinician should take into account the number and intensity of the signs and symptoms of the disorder and any resulting impairment in occupatioQal or social functioning. For the majority of disorders, the following g uidelines may be used: Mild. Few, if any, symptoms in excess of those required to make the diagno- sis are present, and symptoms result in no more than minor impairment in so- cial or occupational functioning. Moderate. Symptoms or functional impairment between "mild" and "se- vere" are present. Severe. Many symptoms in excess of those required to make the diagnosis, or several symptoms that are particularly severe, are present, or the symptoms result in marked impairment in social or occupational functioning. In Partial Remission. The full criteria for the disorder w ere previously met, but currently only some of the symptoms or signs of the disorder remain. In Full Remission. There are no longer any symptoms or signs of the dis- order, but it is still clinically relevant to note the disorder- for example, in an individual w ith previous episodes of Bipolar Disorder w ho has been symptom free on lithium for the past 3 y ears. After a period of time in full remission, the clinician may judge the individual to be recovered and, therefore, would no longer code the disorder as a current diagnosis. The differentiation of In Full Remission from recovered requires consideration of many factors, including the characteristic course of the disorder, the length of time since the last period of disturbance, the total duration of the disturbance, and the need for contin- ued evaluation or prophylactic treatment. Prior History. For some purposes, it may be useful to note a history of the criteria having been met for a disorder even when the individual is considered to be recovered from it. Such past diagnoses of mental disorder would be in- dicated by us ing the specifier Prior History (e.g., Separation Anxiety Disorder, Prior History, for an individual '"'ith a history of Separation Anxiety Disorder wh o has n o current disorder or ·who currently meets criteria for Panic Dis- order). Specific criteria for defining Mild, Moderate, and Severe have been provided for the following: Mental Retardation, Conduct Disorder, Manic Episode, and Major Depressive Episode. Specific criteria for defining In Partial Remission and In Full Remission hav e been provided for the follow ing: Manic Episode, Major Depressive Episode, and Substance Dependence.
  • 32. Use of the Manual Recurrence Not infrequently in clinical practice, individuals after a period of time in which the full criteria for the disorder are no longer met (i.e., in partial or full remission or re- covery) may develop symptoms that suggest a recurrence of their original disorder but that do not yet meet the full threshold for that disorder as specified in the criteria set. It is a matter of clinical judgment as to how best to indicate the presence of these symptoms. The following options are available: • If the symptoms are judged to be a new episode of a recurrent condition, the dis- order may be diagnosed as current (or provisional) even before the fuJJ criteria have been met (e.g., after meeting criteria for a Major Depressive Episode for only 10 days instead of the 14 days usuaJiy required). • If the symptoms are judged to be clinically significant but it is not clear whether they constitute a recurrence of the original disorder, the appropriate Not Other- wise Specified category may be given. • If it is judged that the symptoms are not clinkally significant, no additional current or provisional diagnosis is given, but ''Prior History" may be noted (seep. 2). Princi pal Diagnosis/Reason for Visit When more than one diagnosis for an individual is given in an inpatient setting, the principal diagnosis is the condition established after study to be chiefly responsible for occasioning the admission of the individual. When more than one diagnosis is given for an individual in an outpatient setting, the reason for visit is the condition that is chiefly responsible for the ambulatory care medical services received during the visit. In most cases, the principal diagnosis or the reason for visit is also the main focus of attention or treatment. It is often difficult (and some·what arbitrary) to determine which diagnosis is the principal diagnosis or the reason for visit, especially in situa- tions of "dual diagnosis" (a substance-related diagnosis like Amphetamine Depen- dence accompanied by a non-substance-related diagnosis like Schizophrenia). For example, it may be unclear which d iagnosis should be considered "principal" for an individual hospitalized with both Schizophrenia and Amphetamine Intoxication, be- cause each condition may have contributed equally t<l the need for admission and treatment. Multiple diagnoses can be reported in a multiaxial fashion (seep. 35) or in a non- axial fashion (seep. 37). When the principal diagnosis is an Axis I disorder, this is in- dicated by listing it first. The remaining disorders are listed in order of focus of attention and treatment. When a person has both an Axis I and an Axis II diagnosis, the principal diagnosis or the reason for visit will be assumed to be on Axis I unless the Axis II diagnosis is followed by the qualifying phrase "(Principal Diagnosis)" or "(Reason for Visit)." Provisional Diagnosis The s p ecifier provisional can be used when there is a strong presumption that the full criteria will ultimately be met for a disorder, but not enough information is available
  • 33. 4 Use of the Manual to make a firm diagnosis. The clinician can indicate the diagnostic uncertainty by re- cording "(Provisional)" following the diagnosis. For example, the individual appears to have a Major Depressive Disorder, but is unable to give an adequate history toes- tablish that the full criteria are met. Another use of the term provisional is for those sit- uations in ,vhich differentia] diagnosis depends exclusively on the dLUation of illness. For example, a diagnosis of Schizophreniform Disorder requires a duration of Jess than 6 months and can only be given provisionalJy if assigned before remission has occurred. Use of Not Otherwise Specified Categories Because of the diversity of dinicalprese.ntations, it is impossible for the diagnostic no- menclature to cover every possible situation. For this reason, each diagnostic class has at least one Not Otherwise Specified (NOS) category and some classes have several NOS categories. There are foill situations in which an NOS djagnosis may be appro- priate: • The presentation conforms to the general gwdelines for a mental disorder in the diagnostic class, but the symptomatic picture does not meet the criteria for any of the specific disorders. This would occur either when the symptoms are belov..• the diagnostic threshold for one of the specific disorders or when there is an atypical or mixed presentation. • The presentation conforms to a symptom pattern that has not been included in the DSM-TV Classification but that causes clinicalJy significant distress or impairment. Research criteria for some of these symptom patterns have been included in Appen- dix B ("Criteria Sets and Axes Provided for Further Study"), in which case a page reference to the suggested research cdteria set in Appendix B is provided. • There is uncertainty about etiology (i.e., .-. rhether the disorder is due to a general medicaJ condition, is substance mduced, or is primary). • There is insufficient opportunity for complete data collection (e.g., in emergency situations) or inconsistent or contradictory information, but there is enough infor- mation to place itwitl1in a particuJar diagnostic class (e.g., the clinician determines that tl1e indhridual has psychotic symptoms but does not have enough information to diagnose a specific Psychotic Disorder). Ways of Indicating Diagnostic Uncertainty The following table indicates the various ways in which a clinician may indicate di- agnostic uncertainty:
  • 34. Use of the Manual sl Term Examples of clinical situations V Codes (for Other Conditions That May Insufficient information to know whether or Be a Focus of Clinical Attention) not a presenting problem is attributable to a mental disorder, e.g., Academic Problem; Adult Antisocial Behavior 799.9 Diagnosis or Condition Deferred on Information inadequate to make any diag- Axis I nostic judgment about an Axis I diagnosis or condition 799.9 Diagnosis Deferred on Axis II Information inadequate to make any diag- nostic judgment about an Axis II diagnosis 300.9 Unspecified Mental Disorder Enough information available to rule out a (non psychotic) Psychotic Disorder, but further specification is not possible 298.9 Psychotic Disorder Not Otherwise Enough information available to determine Specified the presence of a Psychotic Disorder, but fur- ther specification is not possible (Class of disorder] Not Otherwise Specified Enough information available to indicate e.g., Depressive Disorder Not Otherwise the class of disorder that is present, but fur- Specified ther specification is not possible, either be- cause there is not sufficient information to make a more specific diagnosis or because the clinical features of the disorder do not meet the criteria for any of the specific cate- gories in that class [Specific diagnosis] (Provisional) Enough information available to make a e.g., Schizophreniform Disorder "working" diagnosis, but the clinician wishes (Provisiona I) to indicate a significant degree of diagnostic uncertainty Frequently Used Criteria . . ,. , Criteria Used to Exclude Other Diagnoses and to Suggest Differential Diagnoses Most of the criteria sets presented in this manual include exclusion criteria that are necessary to establish boundaries between disorders and to clarify differential diag- noses. The several different w ordings of exclusion criteria in the criteria sets through- out DSM-IV reflect the different types of possible relationships among disorders: • "Criteria have never been met for ... " This exclusion criterion is used to define a lifetime hierarchy behveen disorders. For example, a diagnosis of M ajor Depres- sive Disorder can no longer be given once a Manic Episode has occurred and must be cl1anged to a diagnosis of Bipolar I Disorder.
  • 35. Use of the Manual • "Criteria are n ot met for ..." Thls exclusion criterion is used to establish a hier- archy between disorders (or subtypes) defined cross-sectionally. For example, the specifier With Melancholic Features takes precedence over With Atypical Features for describing the current Major Depressive Episode. • udoes not occur exclusively during the course of . .." This exclusion criterion prevents a disorder from being diagnosed when its symptom presentation occurs only during the course of another disorder. For example, dementia is not diag- nosed separately if it occurs only during d elirium; Conversion Disorder is not diagnosed separately if it occurs only during Somatization Disorder; Bulimia Ner- vosa is not diagnosed separately if it occurs only during episodes of AnorexiaNer- vosa. This exclusion criterion is typically used in situations in which the symptoms of one disorder are associated features or a subset of the symptoms of the preempt- ing disorder. The clinician should consider periods of partial re:rrUssion as part of the "course of another disorder." It should be noted that the excluded diagnosis can be given at times when it occurs independently (e.g., when the excluding dis- order is in full remission). • "n ot d ue to the direct physiological effects of a substance (e.g., a drug of abuse, a medication) or a general medical condition." This exclusion criterion is used to indicate that a substance-induced and general medical etiology must be consid- ered and ruled out before the disorder can be diagnosed (e.g., Major Depressive Disorder can be diagnosed only after etiologies based on substance use and a gen- eral medical condition have been ruled out). • "not better accounted for by .. .'' This exclusion criterion is used to indicate that the disorders mentioned in the criterion must be considered in the differential di- agnosis of the presenting psychopathology and that, in boundary cases, clinical judgment ·w jJl be necessary to deter:rrUne whicl1 disorder provides the most appro- priate diagnosis. In such cases, the "Differential Diagnosis" section of the text for the disorders should be consulted for guidance. The general convention in DSM-N is to allow multiple diagnoses to be assigned for those presentations that meet criteria for more than one DSM-N disorder. There are three situations in which the above-mentioned exclusion criteria help to establish a diagnostic hierarchy (and thus prevent multiple diagnoses) or to highlight differen- tial diagnostic considerations (and thus discourage multiple diagnoses): • When a Mental Disorder Due to a General Medical Condition or a Substance- Induced Disorder is responsible for the symptoms, it preempts the diagnosis of the corresponding primary disorder with the same symptoms (e.g., Cocaine-Induced Mood Disorder preempts Major Depressive D isorder). In such cases, an exclusion criterion containing the phrase "not d ue to the direct physiological effects of ... " is included in the criteria set for the primary disorder. • When a more pervasive disorder (e.g., Schizophrenia) has among lts defining symptoms (or associated symptoms) what are the defining symptoms of a les.s per- vasive disorder {e.g., Dysthymic Disorder), one of the following three exclusion criteria appears in the criteria set for the less pervasive disorder, indicating that only the more pervasive disorder is diagnosed: "Criteria have never been met for ...," "Criteria are not met for ...," "d oes not occur exclusively during the course o,f ... "
  • 36. Use of the Manual • When there are particularly difficult differential diagnostic boWldaries, the phrase "not better accoWlted for by ..." is included to indicate that clinical judgment is necessary to determine which diagnosis is most appropriate. For example, Panic Disorder With Agoraphobia includes the criterion "not better accounted for by Social Phobia" and Social Phobia includes ihe criterion "not better accounted for by Panic Disorder Y'lith Agoraphobia" in recognition of the fact that this is a par- ticularly difficult boundary to draw. In some cases, both ruagnoses might be appropriate. Criteria for Substance-Induced Disorders l tis often difficult to determine whether presenting symptomatology is substance in- duced, that is, the direct physiological consequence of Substance Intoxication or Withdrawal, medication use, or toxin exposure. In an effort to provide some assis- tance in making this determination, the hvo criteria listed below have been added to each of the Substance-Induced Disorders. These criteria are intended to provide gen- eral guidelines, but at the same time allow for clinical judgment in determining ·whether or not the presenting symptoms are best accoWlted for by the direct physio- logica l effects of the substance. For further discussion of this issue, seep. 209. B. There is evidence from the history, physical examination, or laboratory findings of either (1) or (2): {1) the symptoms developed during, or w ithin a month of, Substance Intoxication or Withdrawal {2) medication use is etiologically related to the disturbance C. The disturbance is not better accounted for by a disorder that is n ot sub- stance induced. Evidence that the symptoms are better accounted for by a disorder that is not s ubstance induced might include the following: the symptoms precede the onset of the substance use (or medication use); the symp toms persist for a substantial period of time (e.g., about a month) after the cessation of acute withdrawal or severe intoxication, or are substantial- ly in excess of what would be expected given the type, duration, or amount of the s ubstance used; or there is other e'ridenc~ that suggests the existence of an independent non-substance-induced disorder (e.g., a history of recur- rent non-substance-related episodes). Criteria fo r a Mental Disorder Due to a General Medica l Condition The criterion listed below is necessary to establis h the etiological requirement for each of the Mental Disorders Due to a General Medical Condition (e.g., Mood Disor- der Due to H ypothyroidism). For further discussion of this issue, seep. 181. There is evidence from the history, physical examination, or laboratory find- ings that the disturbance is the rurect physiological consequence of a general medical condition.
  • 37. Is Use of the Manual Criteria for Clinical Significance The definition of mental disorder in the introduction to DSM-IV requires that there be dinjcally significant impairment or distress. To highlight the importance of consider- ing this issue, the criteria sets for most disorders include a clinical significance crite- rion (usually worded"... causes dinjcally significant distress or impairment in social, occupational, or other important areas of functioning"). This criterion helps establish the threshold for the diagnosis of a disorder in those situations in which the symp- tomatic presentation by itself (particu1arly in its milder forms) is not inherently pathological and may be encountered in individuals for whom a diagnosis of " mental disorder" would be inappropriate. Assessing whether this criterion is met, especially in terms of role funcpon, is an inherently difficult clinical judgment Reliance on in- fom"ta tion from family members and other third parties (in addition to the individu al) regarding the individual's performance is often necessary. Types of Information in the DSM-IV Text The text of DSM-IV systematically describes each disorder under the following head- ings: "Diagnostic Features"; "Subtypes and/ or Specifiers"; "Recording Procedures"; "Associated Features and Disorders"; "Specific Culture, Age, and Gender Features''; "Prevalence"; "Course"; "Familial Pattern"; and "Differential Diagnosis." When n o information is available for a section, that section is not included. In some instances, when many o f the specific d isorders in a group of disorders share common features, this information is included in the general introduction to the group. D iagnostic Features. This section clarifies the diagnostic criteria and often provides illustrative examples. Subtypes and/or Specifiers. This section provides definitions and brief discussions concerning applicable subtypes and / or specifiers. Recording Procedures. This section provides guidelines for reporting the name of the disorder and for selecting and recording the appropriate ICD-9-CM diagnostic code. It also includes instructions for applying any appropriate subtypes and/ or specifiers. Associated Features and Disorders. This section is usually subdivided into three parts: • Associated descriptive features mrd me11tal disorders. This section includes clinical features that are frequently associated w ith the disorder but that are not consid- ered essential to making the diagnosis. In some cases, these features were consid- ered for inclusion as possible diagnostic criteria but>vereinsufficiently sensitive or specific to be included in the final criteria set. Also noted in this section are other mental disorders associated with the disorder being discussed. It is specified (when known) if t11ese disorders p recede, co-occur Vith, or are consequen ces of the disorder in question (e.g., Alcohol-Induced Persisting Dementia is a consequence •