FINAL PROGRAM - American Society of Gene & Cell Therapy

FINAL PROGRAMAmerican Society of Gene & Cell Therapy13 th Annual Meeting | Washington, DC USA May 19-22, 2010Marriott Wardman ParkASGCT-1209-111Jointly sponsored by Indiana University School of Medicine and the American Society of Gene & Cell Therapywww.asgct.org

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 1Table of ContentsA Welcome from Kenneth Cornetta, MD .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2Committee Meeting Schedule .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3Committee Rosters. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4Planning Committee and Group Coordinating Reviewers. . . . . . . . . . . . . . . . . . . . . . . . . . 8Annual Meeting Supporters.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9Annual Meeting Exhibitors.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10Abstract Reviewers.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11Excellence in Research Award and Travel Grant Recipients. . . . . . . . . . . . . . . . . . . . . . . . 13Outstanding New Investigator & Outstanding Achievement Award Recipients. . . . . . . . . . . 14Faculty Listing.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15General Meeting Information.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19Marriott Wardman Park Hotel Floor Plans .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 23Schedule-at-a-Glance. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25Detailed Program Schedule.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 27Exhibit Hall Floor Plan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 76Exhibitor Descriptions.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 77Exhibitor Information.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 84Washington, DC Fun Facts. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 85Housing Information and Map of Hotel Area... . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 85Abstract Directory. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 86Abstract Author Index.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 143ASGCT Officers and Board of DirectorsPresident (09/10)Kenneth Cornetta, MDPresident-Elect (09/10)Barrie J. Carter, PhDVice President (09/10)R. Jude Samulski, PhDSecretary (10)John F. Engelhardt, PhDTreasurer (11)Beverly L. Davidson, PhDBoard MembersChristopher Baum, MDMichele P. Calos, PhDCynthia Dunbar, MDHelen E. Heslop, MDHarry L. Malech, MDStephen J. Russell, MD, PhDBrian P. Sorrentino, MDSamuel C. Wadsworth, PhDMatthew D. Weitzman, PhDJohn J. Rossi, PhDChair, Advisory Council(ex-officio)Malcolm K. Brenner, MD, PhDEditor-in-Chief, Molecular Therapy(ex-officio)ASGCT Executive Office555 East Wells Street, Suite 1100Milwaukee, WI 53202Phone: 414.278.1341Fax: 414.276.3349info@asgct.orgwww.asgct.orgMary Dean – Executive DirectorErin Hankey – Administrative AssistantKen Janowski – Program ManagerRoseann Marotz – Meetings ManagerDavid Wood – Senior Meetings & Membership ManagerTara Withington, CAE – Consulting Partner

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 3Committee Meeting ScheduleCommittee terms technically commence and conclude at the Annual Meeting. Incoming chair and committee member terms officially go into effect on May 22, 2010at the Business Meeting. All meetings will be held at the Marriott Wardman Park Hotel unless otherwise noted.WEDNESDAY, MAY 19th11:45 am – 12:45 pm Membership Committee Meeting Harding RoomTHURSDAY, MAY 20thInternational Committee MeetingHoover Room12:45 pm – 1:45 pm Education Committee Meeting Park Tower 8216FRIDAY, MAY 21stPublications Committee Meeting Park Tower 821212:30 pm – 1:30 pm Scientific Committee Meetings:Cancer Gene & Cell Therapy; Cardiovascular Gene & Cell Therapy;Embryonic/Somatic Stem Cell and Tissue Engineering; Gene &Cell Therapy of Genetic Diseases; Genetic Vaccines; HemopoieticCell Gene Therapy; Immunology of Gene & Cell Therapy; InfectiousDiseases; Musculo-Skeletal Disorders Gene Therapy; NeuralDisorders Gene Therapy; Oligonucleotide Based Therapies; PhysicalGene & Cell Therapy and Vectorology; Respiratory Tract Gene & CellTherapy; Tissue Engineering; Viral Gene Transfer VectorsThurgood Marshall North and East12:45 pm – 1:45 pm Advisory Council Meeting Park Tower 8222Clinical & Regulatory Affairs Committee Meeting Park Tower 8228Ethics Committee MeetingCongressional RoomTranslational Science & Product Development Meeting Park Tower 82198:30 pm – 10:00 pm Molecular Therapy Editorial Board Meeting Maryland SuiteSATURDAY, MAY 22nd8:00 am – 8:30 am Society Annual Business Meeting Delaware Suite1:15 pm – 2:15 pm Bio-Industry Liaison Committee Meeting Harding RoomSociety Annual Business MeetingThe ASGCT Business Meeting will be conducted on Saturday, May 22, 8:00 am – 8:30 am. A continental breakfast will be served at 7:45 am in the Delaware Suite.All ASGCT members are welcome to attend. Election results will be announced, new officers will be installed and the Society’s finances and membership statistics willbe reviewed. We welcome your input and participation!

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 5Committee RostersEducation CommitteeCo-ChairsLinda B. Couto, PhD (2010 - 2011)Roland W. Herzog, PhD (2008 - 2010)Fulvio Mavilio, PhD (2009 - 2011)MembersLinda B. Couto, PhD (2008 - 2011)William F. Goins, PhD (2007 - 2013)Scott Q. Harper, PhD (2010 - 2013)Karin Jooss, PhD (2007 - 2010)Tal Kafri, PhD (2007 - 2013)Harry L. Malech, MD (2010 - 2013)Robin J. Parks, PhD (2007 - 2010)Suzie H. Pun, PhD (2009 - 2012)Luk Vandenberghe, PhD (2010 - 2013)Embryonic/Somatic Stem Cell andTissue Engineering CommitteeChairGay Crooks, MD (2009 - 2011)MembersKaren S. Aboody, MD (2009 - 2012)Fernando D. Camargo, PhD (2010 - 2013)Gay Crooks, MD (2008 - 2011)James Ellis, PhD (2009 - 2012)Jane Lebkowski, PhD (2010 - 2013)Jan A. Nolta, PhD (2009 - 2010)Kazuo Ohashi, MD, PhD (2006 - 2012)Evan Y. Snyder, MD, PhD, FAAP (2006 - 2012)Alice F. Tarantal, PhD (2009 - 2012)Mark E. Westhusin, PhD (2009 - 2010)Ethics CommitteeChairJonathan Kimmelman, PhD (2008 - 2010)Nelson Wivel, MD (2010 - 2011)MembersRoger H. Bertolotti, PhD (2009 - 2012)Theodore Friedmann, MD (2008 - 2011)Edward I. Ginns, MD, PhD (2009 - 2012)Dieter C. Gruenert, PhD (2010 - 2013)Diane Wara, MD (2007 - 2010)Nelson Wivel, MD (2009 - 2012)Gene & Cell Therapy of GeneticDiseases CommitteeChairValder Arruda, MD, PhD (2010 - 2011)Fabio Candotti, MD (2009 - 2010)MembersValder Arruda, MD, PhD (2007 - 2010)Fatima Bosch, PhD (2010 - 2013)Fabio Candotti, MD (2010 - 2011)Lawrence C. Chan, MD (2010 - 2013)Andrew Davidoff, MD (2010 - 2013)Jim Hu, PhD (2007 - 2010)Stefan Karlsson, MD, PhD (2007 - 2010)Nuria Morral, PhD (2009 - 2012)Amit Nathwani, MD, PhD (2007 - 2010)Mark S. Sands, PhD (2009 - 2010)Thierry C. VandenDriessche, PhD (2009 - 2012)Charles P. Venditti, MD, PhD (2008 - 2011)Robin Ziegler, MS (2010 - 2013)Genetic Vaccines CommitteeChairHelen E. Heslop, MD (2009 - 2011)MembersRonald Alvarez, MD (2006 - 2012)John A. Barrett, MD (2010 - 2013)Si-Yi Chen, MD, PhD (2010 - 2013)K. Reed Clark, PhD (2004 - 2010)Ruxandra Draghia-Akli, MD, PhD (2007 - 2010)Mary Lynne Hedley, PhD (2006 - 2012)Jeffrey J. Molldrem, MD (2010 - 2013)Sattva S. Neelapu, MD (2010 - 2013)David B. Weiner, PhD (2003 - 2010)Hemopoietic Cell Gene TherapyCommitteeChairPunam Malik, MD (2009 - 2010)Michel Sadelain, MD, PhD (2010 - 2011)MembersAlessandro Aiuti, MD, PhD (2008 - 2011)Gianpietro Dotti, MD (2010 - 2013)David W. Emery, PhD (2006 - 2012)Karin Gaensler, MD (2006 - 2012)Manuel Grez, PhD (2009 - 2012)R. Keith Humphries, MD, PhD (2007 - 2010)Harry L. Malech, MD (2009 - 2010)Derek A. Persons, MD, PhD (2007 - 2013)Karen E. Pollok, PhD (2006 - 2012)Barbara Savoldo, MD, PhD (2010 - 2013)Immunology of Gene & Cell TherapyCommitteeChairAdrian J. Thrasher, MD, PhD (2009 - 2011)MembersAndrea Amalfitano, DO, PhD (2010 - 2013)Andrew Byrnes, PhD (2010 - 2013)Youhai H. Chen, MD, PhD (2007 - 2010)Gianpietro Dotti, MD (2009 - 2010)Soosan Ghazizadeh, PhD (2007 - 2010)Roland W. Herzog, PhD (2010 - 2013)Gerald S. Lipshutz, MD (2010 - 2013)John D. Mountz, MD, PhD (2007 - 2013)Daniel A. Muruve, MD (2007 - 2010)Maria-Grazia Roncarolo, MD, PhD (2004 - 2010)Denise Sabatino, PhD (2008 - 2011)Yiping Yang, MD, PhD (2010 - 2013)Infectious Diseases CommitteeChairRoberto Cattaneo, PhD (2009 - 2011)MembersRonald G. Crystal, MD (2009 - 2010)Wayne A. Marasco, MD, PhD (2006 - 2012)Steven Polyak, MD (2010 - 2013)Bruce E. Torbett, PhD, MSPH (2009 - 2012)Jeffrey B. Ulmer, PhD (2006 - 2012)James M. Wilson, MD, PhD (2007 - 2013)Stefan Worgall, MD, PhD (2006 - 2012)

6American Society of Gene & Cell TherapyCommittee RostersInternational CommitteeChairJohn Rasko, MBBS, PhD (2009 - 2011)MembersAlberto Auricchio, MD (2010 - 2013)Christopher Baum, MD (2010 - 2013)Olivier Danos, PhD (2009 - 2010)Guangping Gao, PhD (2009 - 2012)Bobby Gaspar, MD, PhD (2008 - 2011)Salima Hacein-Bey Abina, PhD (2008 - 2011)Takashi Shimada, MD, PhD (2009 - 2012)Sander Van Deventer, MD, PhD (2007 - 2013)Thierry C. VandenDriessche, PhD (2010 - 2013)Seppo Ylä-Herttuala, MD, PhD, FESC (2005 -2011)Membership CommitteeChairDexi Liu, PhD (2010 - 2011)Savio L.C. Woo, PhD (2008 - 2010)MembersMargaret Black, PhD (2010 - 2013)Michele P. Calos, PhD (2010 - 2013)Larry A. Couture, PhD (2009 - 2010)Dexi Liu, PhD (2006 - 2012)Toya Ohashi, MD (2008 - 2011)Isabelle Rivière, PhD (2004 - 2010)Maria-Grazia Roncarolo, MD, PhD (2005 - 2011)John J. Rossi, PhD (2005 - 2011)Savio L.C. Woo, PhD (2010 - 2011)Ex-OfficioRobert M. Frederickson, PhD (2005 - 2011)Musculo-Skeletal Disorders Gene &Cell Therapy CommitteeChairPaula Clemens, MD (2008 - 2010)Jerry R. Mendell, MD (2010 - 2011)MembersJeffrey Chamberlain, PhD (2010 - 2013)Alan R. Davis, PhD (2007 - 2013)Dongsheng Duan, PhD (2004 - 2010)Dan Gazit, DMD, PhD (2004 - 2010)Richard J. Gregory, PhD (2010 - 2013)Dwight Koeberl, MD, PhD (2010 - 2013)Alan J. Nixon, DVM, MS (2007 - 2013)Shin’ichi Takeda, MD, PhD (2010 - 2013)Bing Wang, MD, PhD (2010 - 2013)Neural Disorders Gene & CellTherapy CommitteeChairMaria G. Castro, PhD (2009 - 2011)MembersRobin R. Ali, PhD (2010 - 2013)William J. Bowers, PhD (2009 - 2012)Xandra O. Breakefield, PhD (2009 - 2012)Mary Bartlett Bunge, PhD (2007 - 2010)Maria G. Castro, PhD (2007 - 2010)Beverly L. Davidson, PhD (2008 - 2011)Nicole Deglon, PhD (2004 - 2010)David J. Fink, MD (2010 - 2013)John Forsayeth, PhD (2004 - 2010)Bill Hauswirth, PhD (2010 - 2013)Jeffrey H. Kordower, PhD (2007 - 2010)Anne Messer, PhD (2010 - 2013)Deborah J. Watson, PhD (2009 - 2012)John H. Wolfe, VMD, PhD (2010 - 2013)Nominating CommitteeChairMalcolm K. Brenner, MD, PhD (2008 - 2010)MembersTerence R. Flotte, MD (2009 - 2010)Luigi M. Naldini, MD, PhD (2009 - 2010)Jan A. Nolta, PhD (2009 - 2010)Samuel C. Wadsworth, PhD (2009 - 2011)Oligonucleotide Based TherapiesCommitteeChairBruce Sullenger, PhD (2009 - 2011)MembersC. Frank Bennett, PhD (2010 - 2013)Brian D. Brown, PhD (2010 - 2013)Dirk Grimm, PhD (2010 - 2013)Dieter C. Gruenert, PhD (2004 - 2010)Mark A. Kay, MD, PhD (2009 - 2010)Anton P. McCaffrey, PhD (2006 - 2012)Paul B. McCray, Jr., MD (2008 - 2011)Kevin V. Morris, PhD (2010 - 2013)Matthew H. Porteus, MD, PhD (2006 - 2010)Bruce Sullenger, PhD (2004 - 2010)Marco Weinberg, PhD (2010 - 2013)Jon A. Wolff, MD (2004 - 2010)Physical Gene & Cell Therapy andVectorology CommitteeChairShulin Li, PhD (2009 - 2011)MembersMichele P. Calos, PhD (2007 - 2013)Michael Fons, PhD (2009 - 2012)Richard Heller, PhD (2009 - 2012)R. Scott McIvor, PhD (2009 - 2012)Carol H. Miao, PhD (2009 - 2012)Lluis M. Mir, PhD, DSc (2009 - 2012)Matthew H. Porteus, MD, PhD (2010 - 2012)Sean M. Sullivan, PhD (2010 - 2013)EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 7Committee RostersProgram CommitteeCo-ChairsKenneth Cornetta, MD (2010 - 2011)Ronald G. Crystal, MD (2010 - 2011)Stanton L. Gerson, MD (2008 - 2010)John J. Rossi, PhD (2009 - 2011)MembersValder Arruda, MD, PhD (2010 - 2011)Barry J. Byrne, MD, PhD (2010 - 2011)Bruce A. Bunnell, PhD (2009 - 2011)Fabio Candotti, MD (2009 - 2010)Maria G. Castro, PhD (2009 - 2011)Roberto Cattaneo, PhD (2007 - 2011)Seng H. Cheng, PhD (2010 - 2011)Paula Clemens, MD (2008 - 2010)Laurence JN Cooper, MD, PhD (2009 - 2011)Larry A. Couture, PhD (2010 - 2011)Gay Crooks, MD (2009 - 2011)Todd Giorgio, PhD (2009 - 2010)H. Kirk Hammond, MD (2008 - 2010)Helen E. Heslop, MD (2009 - 2011)Carl H. June, MD (2009 - 2010)Jonathan Kimmelman, PhD (2008 - 2010)Donald B. Kohn, MD (2009 - 2010)Shulin Li, PhD (2009 - 2011)Punam Malik, MD (2009 - 2010)Fulvio Mavilio, PhD (2009 - 2010)Jerry R. Mendell (2010 - 2011)Luigi M. Naldini (2010 - 2011)John Rasko, MBBS, PhD (2009 - 2011)Theresa M. Reinke, PhD (2010 - 2011)Michel Sadelain, MD, PhD (2010 - 2011)Daniel R. Salomon, MD (2010 - 2011)Bruce Sullenger, PhD (2009 - 2011)Adrian J. Thrasher, MD, PhD (2008 - 2011)Thomas Tillett (2008 - 2010)Savio L.C. Woo, PhD (2008 - 2010)Publications CommitteeChairDonald B. Kohn, MD (2009 - 2011)MembersHans-Peter Kiem, MD (2007 - 2013)Arthur W. Nienhuis, MD (2010 - 2013)Michel Sadelain, MD, PhD (2007 - 2013)Rachel Salzman, DVM (2008 - 2011)Brian P. Sorrentino, MD (2007 - 2010)Francis C. Szoka, Jr., PhD (2008 - 2011)Respiratory Tract Gene & CellTherapy CommitteeChairBruce A. Bunnell, PhD (2009 - 2011)MembersDavid A. Dean, PhD (2010 - 2013)John F. Engelhardt, PhD (2010 - 2013)Terence Flotte, MD (2010 - 2013)Deborah Gill, PhD (2008 - 2011)Uta Griesenbach, PhD (2007 - 2010)Larry G. Johnson, MD (2009 - 2010)Jay K. Kolls, MD (2007 - 2013)Carolyn Lutzko, PhD (2007 - 2010)David W. Parsons, PhD (2007 - 2013)Tissue Engineering CommitteeChairDaniel R. Salomon, MD (2010 - 2011)MembersDan Gazit, DMD, PhD (2010 - 2013)William Giannobile, DDS, DMedSc (2010 - 2013)Bruce Levine, PhD (2010 - 2013)Paul Y. Liu, MD, FACS (2010 - 2013)Tatiana Segura, PhD (2010 - 2013)Stephanie Simek, PhD (2010 - 2013)Translational Science & ProductDevelopment CommitteeChairLarry A. Couture, PhD (2010 - 2011)MembersJoy Cavagnaro, PhD, DABT, RAC (2010 - 2013)Kenneth Cornetta, MD (2010 - 2013)Derek Hei, PhD (2010 - 2013)Doug J. Jolly, PhD (2010 - 2013)Ian MacLachlan, PhD (2010 - 2013)Alain Rolland, PhD (2010 - 2013)Richard Snyder, PhD (2010 - 2013)Viral Gene Transfer VectorsCommitteeChairLuigi M. Naldini, MD, PhD (2010 - 2011)R. Jude Samulski, PhD (2009 - 2010)MembersMavis Agbandje-McKenna (2010 - 2013)Frederic D. Bushman, PhD (2007 - 2010)John A. Chiorini, PhD (2010 - 2013)John T. Gray, PhD (2007 - 2013)Brendan Lee, MD, PhD (2008 - 2011)Luigi M. Naldini, MD, PhD (2008 - 2011)Philip Ng, PhD (2009 - 2012)Samuel D. Rabkin, PhD (2009 - 2012)Stephen J. Russell, MD, PhD (2010 - 2013)Dmitry M. Shayakhmetov, PhD (2009 - 2012)Richard O. Snyder, PhD (2007 - 2010)David Strayer, MD, PhD (2009 - 2012)

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 11Abstract ReviewersCommittee ChairJohn F. Engelhardt, PhDRNA Virus VectorsCoordinating ReviewerArthur W. Nienhuis, MDReviewersChristopher Baum, MDFabio Candotti, MDRobert G. Hawley, PhDDavid W. Russell, MD, PhDAAV VectorsCoordinating ReviewerJohn A. Chiorini, PhDReviewersDouglas M. McCarty, PhDDavid V. Schaffer, PhDMatthew D. Weitzman, PhDXiao Xiao, PhDAdenovirus and Other DNA VirusVectorsCoordinating ReviewerPhilip Ng, PhDReviewersAnja Ehrhardt, PhDJoseph C. Glorioso, III, PhDFlorian Kreppel, PhDRobin J. Parks, PhDDNA Vectorology & Gene TargetingCoordinating ReviewerMichele P. Calos, PhDReviewersDeborah Gill, PhDPerry B. Hackett, PhDJakob Giehm Mikkelsen, PhDMatthew H. Porteus, MD, PhDPhysical Methods of DeliveryCoordinating ReviewerNancy Smyth Templeton, PhDReviewersMichael A. Barry, PhDJeffrey Hughes, PharmD, PhDChristian Plank, PhDChun Wang, PhDChemical and Molecular ConjugatesCoordinating ReviewerSuzie H. Pun, PhDReviewersHideyoshi Harashima, PhDTheresa M. Reineke, PhDTatiana Segura, PhDMillicent Sullivan, PhDGenetic and MeTABolic Diseases Gene& Cell TherapyCoordinating ReviewerCary Harding, MDReviewersDwight Koeberl, MD, PhDBrendan Lee, MD, PhDJon A. Wolff, MDCardiovascular Gene & Cell TherapyCoordinating ReviewerBarry J. Byrne, MD, PhDReviewersDavid A. Dichek, MDRoger J. Hajjar, MDCathryn S. Mah, PhDChristina A. Pacak, PhDNeurologic & Ophthalmic Gene & CellTherapyCoordinating ReviewerMichael Kaplitt, MD, PhDReviewersKrystof Bankiewicz, MD, PhDNicholas Boulis, MDMiguel Sena-Esteves, PhDDeborah J. Watson, PhDMusculo-skeletal Gene & CellTherapyCoordinating ReviewerAlan R. Davis, PhDReviewersJeffrey Chamberlain, PhDPaula Clemens, MDScott Q. Harper, PhDTerri A. Zachos, DVM, PhDInfectious Diseases and VaccinesCoordinating ReviewerJohn A. Zaia, MDReviewersAnn M. Leen, PhDBruce E. Torbett, PhD, MSPHGrant D. Trobridge, PhDDorothee von Laer, MDCancer - ImmunotherapyCoordinating ReviewerHelen E. Heslop, MDReviewersRonald Alvarez, MDJeffrey J. Molldrem, MDJames J. Mulé, PhDDavid B. Weiner, PhDCancer – Oncolytic VirusesCoordinating ReviewerRonald Rodriguez, MD, PhDReviewersWinald Gerritsen, MD, PhDChinghai Kao, PhDDavid H. Kirn, MDMasato Yamamoto, MD, PhDCancer - Targeted Gene & CellTherapyCoordinating ReviewerWilliam S. M. Wold, PhDReviewersKaren S. Aboody, MDFrank Marini, PhDStephen J. Russell, MD, PhDRichard G. Vile, PhDHematologic and Immunologic Gene& Cell TherapyCoordinating ReviewerMichel Sadelain, MD, PhDReviewersGay Crooks, MDDavid W. Emery, PhDDavid Klatzmann, MD, PhDAdrian J. Thrasher, MD, PhD

12American Society of Gene & Cell TherapyAbstract ReviewersLung and Respiratory Disease Gene &Cell TherapyCoordinating ReviewerTerence R. Flotte, MDReviewersDongsheng Duan, PhDLarry G. Johnson, MDMaria Limberis, PhDPatrick L. Sinn, PhDImmunologic & Host Responses inGene & Cell TherapyCoordinating ReviewerPedro Lowenstein, MD, PhDReviewersRenier J. Brentjens, MD, PhDEvanthia Galanis, MD, DScMaciej Lesniak, MD, FACSLily Wu, MD, PhDGene RegulationCoordinating ReviewerOlivier Danos, PhDReviewersMichael N. Antoniou, PhDGiuliana Ferrari, PhDDirk M. Nettelbeck, PhDPaul D. Robbins, PhDOligonucleotide & RNAi TherapeuticsCoordinating ReviewerPeter Glazer, MD, PhDReviewersAlan Gewirtz, MDPaloma H. Giangrande, PhDDieter C. Gruenert, PhDMark A. Kay, MD, PhDStem Cell TherapiesCoordinating ReviewerDonald B. Kohn, MDReviewersEmanuela M. Bruscia, PhDR. Keith Humphries, MD, PhDCarolyn Lutzko, PhDAlice F. Tarantal, PhDCell Processing and VectorProductionCoordinating ReviewerIsabelle Rivière, PhDReviewersAdrian P. Gee, PhDStephen M. Kaminsky, PhDBruce L. Levine, PhDJ. Fraser Wright, PhDSpecial thanks to the abstract reviewers for their time and expertise.EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 19General Meeting InformationAMERICAN SOCIETY OF GENE & CELL THERAPYMission and GoalsThe American Society of Gene & Cell Therapy (ASGCT) is a professionalnon-profit medical and scientific organization dedicated to the understanding,development and application of genetic and cellular therapies and the promotionof professional and public education in the field. ASGCT is the largest medicalprofessional organization representing researchers and scientists dedicated todiscovering new gene and cell therapies. ASGCT was established in 1996, andhas grown to 2,000 members from around the world.The Society’s goals are to:• Promote Research, Development and Application of Genetic and CellularTherapies to a Wide Variety of Human Diseases• Exchange Information and Promote Education Among Professionals andthe Public Through the Society’s Annual Meetings, the ASGCT Journal,Molecular Therapy, and Interactions with Scientific, Medical, and RegulatoryCommunitiesThe ASGCT 13th Annual Meeting will serve as a comprehensive forum to achievethese goals.Abstract Volume – Molecular TherapyAll abstracts, except Late Abstract Submissions, accepted for presentation atthe ASGCT 13th Annual Meeting have been published in the May supplementof Molecular Therapy. Each attendee will receive one copy of the supplementalong with their registration materials. Late Abstract Submissions accepted forpresentation have been printed in a booklet that will be distributed to eachattendee.AdmissionOfficial name badges will be required for admission to all ASGCT sessions. AllAnnual Meeting attendees receive a name badge with their registration bag.Name badges should be worn at all times inside the hotel, as badges will beused to control access to sessions and activities. Attendees are cautioned againstwearing their name badges while away from the hotel as badges may drawunwanted attention to your status as visitors to Washington, DC.Business Center (FedEx Office)There is a FedEx Office located in the Marriott Wardman Park Hotel. It is openMonday – Friday from 7:00 am to 7:00 pm and closed on Saturday andSunday.Business MeetingJoin the Society’s leadership for a business meeting and continental breakfast.Saturday, May 22, 20108:00 am – 8:30 am (A light continental breakfast will be offered at 7:45 am)Room Delaware SuiteAll members are welcome. See page 3 for more details.Camera/Recording PolicyDue to privacy issues, with the exception of a hired professional photographer,it is the policy of ASGCT that no cameras, camera phones, or video recorders arepermitted in the meeting sessions, exhibit hall, or poster sessions. Please refrainfrom taking any photos in those locations. Audio taping is also prohibited.Cell Phones & PDAsFor the courtesy of all presenters and attendees, please ensure that cell phoneand PDA ringers are turned off or silenced during all sessions as they mayinterfere with session audio.Committee MeetingsMost standing and scientific committees will meet during the Annual Meeting.See page 3 for Committee Meeting information.Concierge DeskWashington D.C. and the Woodley Park neighborhood offers a wide variety ofactivities and restaurants to meet all tastes and budgets. A Concierge Desk islocated in the Lobby of the hotel that can help you with your city needs andreservations.Concierge Desk HoursSunday through Saturday7:00 am – 7:00 pmAdmission by Ticket OnlySome sessions at the Annual Meeting will require an additional ticket to controlaccess and capacity. Tickets for these sessions are not included in the meeting’sregular registration fees. Tickets will be collected at the door by ushers. Thereare still a limited number of tickets available for the Meet-the-Investigatorsessions, which may be obtained at the Registration Desk. Meet-the-Investigatortickets are $30.

20American Society of Gene & Cell TherapyGeneral Meeting InformationContinuing Medical EducationAccreditation/Credit DesignationThis activity has been planned and implemented in accordance with the EssentialAreas and policies of the Accreditation Council for Continuing Medical Education(ACCME) through the joint sponsorship of Indiana University School of Medicineand the American Society of Gene & Cell Therapy. Indiana University School ofMedicine is accredited by the ACCME to provide continuing medical education forphysicians.NOTE: Sessions marked with an asterisk (*) are not part of the CME program.Designation StatementIndiana University School of Medicine designates this educational activity for amaximum of 37.5 AMA PRA Category 1 Credits. Physicians should only claimcredit commensurate with the extent of their participation in the activity.CME CertificatesParticipants requiring CME certificates must go to the Registration Desk andcomplete a CME form. CME certificates will be mailed to participants after themeeting. There is a CME fee of $50 USD for the 13th Annual Meeting.DisclosureIn accordance with the Accreditation Council for Continuing Medical Education(ACCME) Standards for Commercial Support, educational programs sponsoredby Indiana University School of Medicine (IUSM) must demonstrate balance,independence, objectivity, and scientific rigor. All faculty, authors, editors, andplanning committee members participating in an IUSM-sponsored activity arerequired to disclose any relevant financial interest or other relationship with themanufacturer(s) of any commercial product(s) and/or provider(s) of commercialservices that are discussed in an educational activity.NoteWhile it offers CME credits, this activity is not intended to provide extensivetraining or certification in the field.Educational Methods and MaterialsLectures, Case Presentations, Panel Discussions, Question and Answer Sessions,Audio/Video Presentations, Abstracts, PostersEducational ObjectivesAt the conclusion of the activity, the participant should be able to:Provide advice to patients who inquire about the potential of gene and celltherapy or the availability of open clinical trials, based on their exposure to thecurrent clinical trials in gene and cell therapies.Better instruct their students in medical school and other health venues using thestate-of-the-art basic science and clinical trials data presented at the meeting.Use the latest advances in gene and cell therapy to enhance their researchmission, as physician scientists conducting basic and clinical research.Demonstrate improved regulatory compliance in conducting gene and celltherapy clinical trials, through exposure to NIH and FDA faculty during theeducational program.Evaluation MethodEvaluation by questionnaire will address program content, presentation, andpossible bias.NeedsClinical gene transfer has become more and more complex due to ongoingdevelopments in the fields of gene and cell therapy itself, together withbioethics, research integrity, and financial conflicts, as well as federalmandates, regulations and guidelines. Oligonucleotide Therapies, Novel VectorDevelopment, Host-Vector Interactions and Vaccine Therapies will be discussedas well as many other scientific topics. This meeting will provide an educationalforum for scientists and clinicians to expand their knowledge about the broaddevelopments in these fields.Target AudienceThe target audience includes basic science and translational researchers, clinicalinvestigators, physicians, postdoctoral fellows, graduate students, employees offederal government and regulatory agencies, and other healthcare professionalswith an interest in the latest advancements in the field of gene and cell therapy.EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 21General Meeting InformationExhibitsExhibits will be located in Exhibit Hall C, of the Marriott Wardman Park Hotel.The companies, organizations and institutions exhibiting at the ASGCT AnnualMeeting will be providing you with the latest information on products andservices directly related to your professional needs, as well as recruiting for openpositions. An Exhibit Hall Social will be held on Wednesday evening and a coffeesocial will be offered on Thursday in the exhibit hall. All participants are urged toallow adequate time in your daily schedule to visit the exhibits, as they are anintegral part of the success of the meeting.Exhibit Hall HoursExhibits will be open Wednesday, May 19 through Friday, May 21, 2010.Wednesday, May 19 7:00 pm – 9:00 pmThursday, May 20 9:15 am – 10:30 amThursday, May 20 6:15 pm – 8:15 pmFriday, May 21 6:30 pm – 8:30 pmGuest AttendanceASGCT asks registered attendees to refrain from taking children, spouses, orguests to any educational session or functions offered at the 13th AnnualMeeting.Internet Access & PolicyInternet access will be available at the Marriott Wardman Park Hotel to allmeeting attendees. Limited computer stations will be provided. When others arewaiting at the internet kiosks, please limit your Internet use to 15 minutes ata time so other attendees can access the internet as well. If you have a laptop,the Marriott Wardman Park offers wireless internet access at certain locationswithin the facility. For guests staying at the Marriott Wardman Park in the ASGCTroom block, free internet access is available in their hotel rooms as well as thehotel’s lobby.Job BankAll openings posted as of April 23, 2010 on the ASGCT Job Bank have beenincluded in the Jobs Available Booklet found in the registration bags. Contactinformation is included in the booklet. Job postings for open positions andrésumés may be posted on the Job Posting boards in Exhibit Hall C. You areresponsible for providing multiple copies of your posting. A number of tables andchairs will also be available in the job exchange center for interview use.Lead RetrievalA lead retrieval system has been made available to all exhibitors of the ASGCT13th Annual Meeting. Exhibitors may ask to scan attendee name badges with ahand held scanner in order to obtain attendee contact information.Materials DistributionPlease refrain from distributing promotional materials throughout the meeting;these may only be distributed from an exhibit booth in Exhibit Hall C.MediaMembers of the working media may register for the 13th Annual Meeting inthe Press Room – Buchanan Room. Interview space, telephones, and internetaccess are available for the convenience of media representatives covering themeeting. Press must register, provide credentials, and wear their press badge foradmittance to ASGCT sessions. Assistance will be provided to members of themedia that would like to schedule interviews.No SmokingSmoking is prohibited at all 13th Annual Meeting sessions and events.The Marriott Wardman Park is a non-smoking hotel.

22American Society of Gene & Cell TherapyGeneral Meeting InformationPostersAbstract Posters will be on display in Halls B-South and C.Thursday, May 20Abstract Poster Session I10:00 am – 12:00 pm Poster Setup by Authors12:30 pm – 8:15 pm Poster Viewing(authors present from 6:15 pm – 8:15 pm)6:15 pm – 8:15 pm Exhibit Hall Open6:15 pm – 8:15 pm Welcome Reception, Exhibits, and PosterSession8:15 pm – 8:45 pm Authors Remove PostersFriday, May 21Abstract Poster Session II7:00 am – 12:00 pm Poster Setup by Authors12:00 pm – 8:30 pm Poster Viewing(authors present from 6:30 pm – 8:30 pm)6:30 pm – 8:30 pm Exhibit Hall Open6:30 pm – 8:30 pm Networking Reception, Exhibits, and PosterSession8:30 pm – 9:00 pm Authors Remove PostersSaturday, May 22Abstract Poster Session III7:00 am – 12:00 pm Poster Setup by Authors12:00 pm – 8:00 pm Poster Viewing(authors present from 6:00 pm – 8:00 pm)5:00 pm – 6:00 pm Poster Hall Social in Atrium6:00 pm – 8:00 pm Poster Session8:00 pm – 8:30 pm Authors Remove PostersPress RoomThe Press Room is located in the Marriott Wardman Park Hotel, Buchanan Room.Press Room HoursWednesday, May 19Thursday, May 20Friday, May 21Saturday, May 223:00 pm – 6:00 pm8:00 am – 5:00 pm8:00 am – 5:00 pm8:00 am – 5:00 pmRegistration DeskName badges, final programs, and abstract supplements will be distributed atthe registration desk located outside of Exhibit Hall C in the atrium, exhibitionlevel of the Marriott Wardman Park Hotel.Registration Desk HoursTuesday, May 185:00 pm – 8:00 pmWednesday, May 19 7:00 am – 8:00 pmThursday, May 207:00 am – 5:00 pmFriday, May 217:30 am – 5:00 pmSaturday, May 227:30 am – 5:00 pmShuttle BusASGCT will not be providing shuttle transportation for the 13th Annual Meeting.Speaker Ready RoomThe Speaker Ready Room is located behind the registration desk located outsideof Exhibit Hall C in the atrium of the Marriott Wardman Park Hotel.All faculty must deliver their presentations to the Speaker Ready Room the daybefore their session or at least four hours prior to their presentations. Equipmentis available for faculty to review their materials. Audiovisual personnel will beavailable for assistance. Please mark your materials (your name, session andspeaker order) so the materials can be returned to you. The Society stronglyencourages faculty to pre-load presentations in the Speaker Ready Room; thosefaculty who load presentations in the meeting rooms during the sessions willhave that time deducted from their presentation time by the Chair.ASGCT strongly encourages faculty presenting on Wednesday of the AnnualMeeting to check-in at the Speaker Ready Room on Tuesday, May 18 to avoidcongestion.Avoid delays and check-in early!Speaker Ready Desk/Room HoursTuesday, May 185:00 pm – 8:00 pmWednesday, May 19 6:30 am – 9:00 pmThursday, May 206:30 am – 7:00 pmFriday, May 217:00 am – 7:00 pmSaturday, May 227:00 am – 3:00 pmSpecialty NeedsIf you require special accommodations in order to fully participate in themeeting, please visit the Registration Desk; ASGCT staff will be happy to assistyou with your specific needs.EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 23Hotel Floor PlanseXHIBIT hALL• Exhibit Hall• Internet Kosks• Job Exchange• Poster Hall• Registration• Speaker Ready Room

24American Society of Gene & Cell TherapyHotel Floor PlansLobby level• Plenary Lecture Hall• Session Rooms(Education, Oral Abstract,Scientific)82098210821182128216821782188219822282238224822682288229mezzanine level• Committee Meetings• Press Room – Buchanan• Session RoomsEXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 25Schedule-at-a-Glance (This program is subject to updates/changes)tuesday, may 185:00 pm – 8:00 pm Registration OpenWednesday, may 197:00 am – 8:00 pm Registration Open8:30 am – 12:15 pm ASGCT Board of Directors Meeting8:30 am – 11:30 pm Scientific Symposia Session I:Cell Therapy BioProcessing Symposium and International Symposium: A Global Gene Therapy Renaissance1:00 pm – 3:00 pm Scientific Symposia Session II3:30 pm – 5:00 pm Education Session I5:30 pm – 7:00 pm Education Session II7:00 pm – 9:00 pm Exhibit Hall Welcome ReceptionThursday, may 207:00 am– 5:00 pm Registration Open8:00 am– 9:15 am George Stamatoyannopoulos Lecture – Keynote: Hal E. Broxmeyer, PhD:Understanding and Enhancing Stem/Progenitor Cell Function and Engraftment9:15 am– 10:30 am Exhibit Hall Coffee Social10:30 am– 12:30 pm Scientific Symposia Session III12:30 pm– 1:45 pm Meet-the-Investigator Sessions12:30 pm– 8:15 pm Poster Viewing (Authors present from 6:15 pm – 8:15 pm)2:00 pm– 4:00 pm Oral Abstract Session I4:30 pm– 6:15 pm Outstanding New Investigator Symposium6:15 pm– 8:15 pm Exhibit Hall Open & Networking Reception Poster Session I7:00 pm– 10:00 pm Foundation Supported Symposium: Expanding Frontiers in Spinal Muscular Atrophy Gene Therapy

26American Society of Gene & Cell TherapySchedule-at-a-Glance (This program is subject to updates/changes)friday, may 217:30 am– 5:00 pm Registration Open8:00 am– 10:00 am Plenary Session: Top Oral Abstract Presentations10:30 am– 12:30 pm Scientific Symposia Session IV12:30 pm– 8:30 pm Poster Viewing (Authors present from 6:30 pm – 8:30 pm)2:00 pm– 4:00 pm Oral Abstract Session II4:30 pm– 6:30 pm Presidential Symposium – Keynote Speakers:Katherine A. High, MD: Outstanding Achievement Award LectureJean Bennett, MD, PhD: An Aye for Gene Therapy: Lessons from a Clinical Trial for Congenital BlindnessDavid A. Williams, MD: New Approaches to Gene Therapy for Fanconi Anemia6:30 pm– 8:30 pm Exhibit Hall Open & Networking Reception Poster Session II7:00 pm– 10:00 pm Foundation Supported Symposium:Progress and Prospects for Gene Therapy for CGD and Other Primary ImmunodeficienciesSATURDAY, MAY 227:30 am– 5:00 pm Registration Open8:00 am– 8:30 am ASGCT Business Meeting (with continental breakfast)8:30 am– 10:30 am Scientific Symposia Session V11:00 am– 1:00 pm Oral Abstract Sessions III1:00 pm– 8:00 pm Poster Viewing (Authors present from 6:00 pm – 8:00 pm)1:00 pm– 2:15 pm Meet-the-Investigator Sessions1:00 pm– 2:45 pm ASGCT Board of Directors Meeting3:00 pm– 5:00 pm Oral Abstract Sessions IV5:00 pm– 6:00 pm Poster Hall Social in Atrium6:00 pm– 8:00 pm Poster Session III8:00 pm 13th Annual Meeting ConcludesEXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 27Program ScheduleWednesday, May 19Scientific Symposium 1008:30 am - 11:30 amRoom: Maryland SuiteCell Therapy BioProcessing SymposiumCo-ChairsBoro Dropulic, PhD & Thomas TillettSpeakersDavid L. Urdal, PhDManufacturing of Sipuleucel-T for the Treatment of Men with Metastatic, Castrate Resistant Prostate CancerSipuleucel-T is an autologous active cellular immunotherapy for men with late stage prostate cancer. It is comprised of a patient’s peripheral blood mononuclear cells, includingantigen presenting cells that have been cultured with a recombinant antigen delivery cassette composed of prostatic acid phosphatase and granulocyte-macrophagecolony stimulating factor. The development of sipuleucel-T will be discussed and the manufacture of this novel product candidate will be described.Gary C. du Moulin, PhD, MPHIncorporating the Concepts of Modern Quality Systems into Cell-based Product DevelopmentWell understood manufacturing processes that identify critical sources of variability can lower risk and lead to safe and efficacious treatment modalities that consistentlydeliver the intended therapeutic performance. The evolution of pharmaceutical quality systems and its focus on patient safety brings the application of a scientific approachand quality risk assessment into practice. This presentation introduces developers to the principles of risk management and quality by design, concepts that can assist ininsuring that quality attributes are identified early in the product design phase and incorporated into the control of critical processes for cell and gene therapy products.Wednesday, May 19 thJane S. Lebkowski, PhDDevelopment of Human Embryonic Stem Cells for Therapeutic ApplicationsHESC-based regenerative cell therapies require 1) evidence for reliable production and quality control of product manufacturing, 2) rigorous safety testing in preclinicalmodels, and 3) the design of clinical trial protocols that assess the safety and benefit of the therapy in appropriate patient populations. GRNOPC1 is a population ofallogeneic cells containing oligodendrocyte progenitors derived from characterized, dedicated, human embryonic stem cell banks. GRNOPC1 induces myelination of axonsin rats with spinal cord injuries and in Shiverer mice, which lack compact myelin, and also produces numerous neurotrophic factors such as midkine, BDNF, and activin.Extensive preclinical studies were performed to determine the distribution of GRNOPC1 as well as any potential toxicities after injection near the thoracic injury epicenter.Based on this IND application, the FDA has granted clearance for Geron to initiate a human clinical trial to assess the safety of GRNOPC1 in patients with subacute,complete ASIA A, thoracic injuries whose last fully preserved neurological level is T3 to T10.Madhusudan V. Peshwa, PhDUse of Flow Electroporation to Load Human Cells to Deliver Clinically Relevant Genes for Cell TherapeuticsThe ability to specifically enhance/augment biological function of cells using safe, non-gene modifying technologies with ability to deliver the product at clinical/commercialscale using automated, regulatory-compliant, cost-effective processes overcomes the key hurdle in developing “effective” cellular therapies. This presentation providesan overview of our experiences in development and characterization of cellular products using immune cells and stem cells that have been engineered to deliver clinicallyrelevant potency/biological activity. Specific case studies discussed will include clinical/commercial delivery of a (1) a patient-specific cellular vaccine marketed as anOncology therapy in Japan and (2) an engineered endothelial stem cell product for treatment of pulmonary arterial hypertension (PAH) in phase I/II trials in Canada.Mitchell Finer, PhDChallenges in the Manufacturing Scale-Up of hES Cell Derived TherapeuticsHuman Embryonic Stem (hES) Cells have been traditionally derived and passaged as adherent clumps of cells on mouse or human fibroblast feeder layers. In order toproduce the quantities of cells sufficient for preclinical development and human clinical trials at an acceptable quality standard, methodology must be developed to enablexeno product free/serum free culture of hES cells as single cells in the absence of feeder lines. Further, while growth on plastic can support limited preclinical and clinicaldevelopment in some indications, achieving the scale of hES cell amplification necessary to treat diseases such as Type 1 Diabetes that require significant cell numbers(~100 billion differentiated cells), the ability to expand ES cells in suspension in the absence of differentiation, and the ability to synchronously differentiate large numbersof cells is required for product development in Type I Diabetes. Data describing the generation of feeder-free cGMP derived hES cell banks, expansion of large scalehES cell cultures in the undifferentiated state and scaled differentiation in suspension of hES-cells into pancreatic b-cell progenitors will be presented.

28American Society of Gene & Cell TherapyProgram ScheduleWednesday, May 19 thMichelle Williams, PhDDevelopment of Prochymal, an Adult MSC TherapyOsiris has been developing stem cell therapies to treat unaddressed medical needs since 1992. An important part of this process has been navigating the regulatorypathway, particularly through work in the lead indication, graft-versus-host-disease. In 2005, Osiris secured the first ever Fast Track and Orphan Drug designations fromFDA for a stem cell product, followed by Orphan drug designation in Europe as well. In 2008, FDA and Health Canada granted approval for a pediatric expanded accessprogram, providing all children with severe GvHD access to our stem cell drug, Prochymal. The late stage clinical development process is an instructive case study ofdevelopment of a novel therapy for a orphan indication.Scientific Symposium 1018:30 am - 11:30 amRoom: Marriott Ballroom Salon 1A Global Gene Therapy RenaissanceChairJohn Rasko, MBBS, PhDSpeakersDe-Chao Michael Yu, PhDClinical Development of KH901, a Conditionally Replicating Oncolytic Adenovirus Encoding Human GM-CSF, in Patients with Recurrent Head andNeck CancersKH901 is a conditionally replicating oncolytic adenovirus, in which the viral E1 genes are under the control of a modified telomerase promoter and a cDNA gene of granulocytemacrophage colony-stimulating factor (GM-CSF) is inserted in the E3 region. Preclinical studies have demonstrated that KH901 selectively replicates in telomeraseupregulatedand E2F-positive tumor cells and has strong anti-tumor activity. A total of 110 patients with recurrent head and neck cancer have been enrolled into clinicaltrials in which KH901 was given intratumorally while chemotherapy was the standard of care. KH901 was found to be well tolerated and safe while a significant immuneresponses and pro-longed progression-free survival were observed when compared to the chemotherapy group.Christoph Klein, MDGene Therapy for Wiskott-Aldrich SyndromeWiskott-Aldrich syndrome (WAS) is a primary immunodeficiency disorder associated with thrombocytopenia, eczema and autoimmunity. We treated ten WAS patients bytransfusion of autologous, genetically modified hematopoietic stem cells (HSC) between 2006 and 2009. We demonstrate sustained WAS protein (WASP) expressionin HSC, lymphoid and myeloid cells, and platelets after gene therapy. T and B lymphocytes, natural killer (NK) cells, and monocytes were functionally corrected. Thepatients´ clinical condition markedly improved with respect to hemorrhagic diathesis, eczema, autoimmunity, and predisposition to severe infections. Genome-wide insertionsite analysis demonstrated vector integration that targeted multiple genes controlling growth development and immunological responses in a persistently polyclonalhematopoiesis.Yasutomo Nasu, MD, PhDProstate Cancer Gene Therapy in Japan - from HSV-tk to REIC/Dkk-3Intraprostatic therapeutic gene transduction (in situ gene therapy) is one of the potent therapeutic option for prostate cancer gene therapy aiming at antimetastatic benefitsthrough the generation of immune cell-mediated cytotoxic activities that affect not only the primary tumor but also metastatic lesion. Many clinical trials with HerpesSimplex Virus Thymidine Kinase (HSV-tk) gene therapy have been conducted in many institutes showing clinical safety and efficacy including Japanese trial (MolecularTherapy 15:834, 2007). Also immunomodulatory in situ gene therapy using adenoviral Interleukin-12 gene is under way in Japan. As a preclinical study, new therapeuticgene REIC/Dkk3 has been proved to be potential therapeutic gene for prostate cancer as it has induces local apoptosis and systemic immune activation. (Cancer Research65:9617, 2005, Cancer Gene Therapy 14:765,2007, Int J Oncol 34:657,2009, J Bio Chem 2009 online). In this symposium ongoing development of in situ genetherapy for prostate cancer will be reported with regard to systemic immune activation.EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 29Program ScheduleChae-Ok Yun, PhDA Phase I Study of Relaxin-Expressing Oncolytic AdenovirusOncolytic virotherapy is the use of genetically engineered viruses that specifically target and destroy tumor cells via their cytolytic replication cycle. An important issue inreplicating virus-based cancer gene therapy that has received little attention is the limited distribution such viruses have been able to achieve in solid tumors. With the aimof improving viral distribution and tumor penetration for cancer gene therapy, we have developed a novel relaxin-expressing oncolytic adenovirus, DWP418. We carried outa phase I study of DWP418 in patients with recurrent solid tumors. The preliminary results show that intratumoral administration of DWP418 is feasible, well tolerated,and associated with biological activity.Wednesday, May 19 thSeppo Ylä-Herttuala, MD, PhD, FESCAdVEGF-D Local Vascular Gene Transfer Program - To Reduce Graft Stenosis in Dialysis PatientsOncolytic virotherapy is the use of genetically engineered viruses that specifically target and destroy tumor cells via their cytolytic replication cycle. An important issue inreplicating virus-based cancer gene therapy that has received little attention is the limited distribution such viruses have been able to achieve in solid tumors. With the aimof improving viral distribution and tumor penetration for cancer gene therapy, we have developed a novel relaxin-expressing oncolytic adenovirus, DWP418. We carried outa phase I study of DWP418 in patients with recurrent solid tumors. The preliminary results show that intratumoral administration of DWP418 is feasible, well tolerated,and associated with biological activity.Alessandro Aiuti, MD, PhDGene Therapy for Primary ImmunodeficienciesGene therapy with hematopoietic stem cells is an attractive therapeutic strategy for several forms of primary immunodeficiencies. Results of the ADA-SCID and SCID-X1trials have shown long-term restoration of immune competence and clinical benefit. The use of a reduced-dose conditioning was crucial to allow substantial engraftment ofmultipotent gene-corrected hematopoietic stem cells. Self-inactivating lentiviral vectors have recently entered into the clinic and should provide significant advantages overgammaretroviral vectors.Lunch Break11:30 am – 1:00 pmScientific Symposium 1101:00 pm - 3:00 pmRoom: Thurgood Marshall WGene and Cell Therapy Translational StudiesChairJ. Kevin Donahue, MDSpeakersJ. Kevin Donahue, MDGene Therapy for Atrial FibrillationAtrial fibrillation affects 2-5 million people in the US and millions more around the world. Mechanisms known to sustain the arrhythmia include structural and electrical remodeling.We developed a novel method for atrial gene transfer that paints the vector on the atrial epicardium. Using this method with adenovirus vectors and a transgeneencoding a dominant negative potassium channel mutation, we show elimination of atrial fibrillation.Douglas W. Losordo, MDAutologous CD34 + Cell Therapy for Ischemic Tissue RepairPreclinical studies documented the potential therapeutic potency of endothelial progenitor cells, both as cultured and freshly isolated CD34+ cells. Phase I and II clinical trialsusing autologous, GCSF mobilized autologous CD34+ cells have been completed in patients with refractory angina and critical limb ischemia. These studies provide data supportingfeasibility, safety and bioactivity. Importantly, the early evidence suggests the efficacy of CD34+ cells and provides important data regarding endpoints and powercalculations for later phase studies. Accordingly, the goal of ischemic tissue repair appears feasible and is being approached in human clinical trials.

30American Society of Gene & Cell TherapyProgram ScheduleWednesday, May 19 thBarry J. Byrne, MD, PhDTherapeutic Strategies for Pompe Disease: Fact or FictionEarly presentation of cardiac dysfunction and the diagnosis of primary cardiomyopathy in infancy and childhood is most often associated with a genetic etiology. Oneexample of early cardiomyopathy is Pompe disease due to striated muscle glycogen storage. In order to develop a specific treatment based gene transfer, the presentationwill focus on systemic and cardiac gene transfer as an approach to disease management. Additional insight into therapeutic strategies is gained from the ongoing study ofa cohort of patients who have received enzyme replacement therapy. The rational for the first clinical gene transfer trial in Pompe disease will be presented.Patrick Most, MDS100A1: A Novel Molecular Therapeutic Advance for Heart FailureAdvanced understanding of the functional networks controlling cardiomyocyte performance together with the evolution of safe and efficient gene transfer technologieshave provided the foundation for the development of an innovative and novel genetically-targeted HF therapy resulting from the unique molecular profile of the cardiomyocyteCa2+ sensor protein S100A1. Here we show profound long-term therapeutic effectiveness and a favorable safety profile for AAV9-S100A1 gene therapy in apreclinical HF model employing cardiac-targeted gene delivery techniques and a gene dosage in pigs that are directly applicable to humans.Scientific Symposium 1111:00 pm - 3:00 pmRoom: Wilson ABCEthical Issues with Embryonic Stem Cells and Induced Pluripotent Stem CellsChairJonathan Kimmelman, PhDSpeakersJonathan D. Moreno, PhDUpdate on Ethical Issues in Stem Cell ResearchIn this talk I review the history of the embryonic stem cell debate and describe the current policy situation in the US and abroad. I then characterize the significance ofwork on induced pluripotent stem cell (iPSC) technology for the ongoing debate. In brief, with iPSC’s the controversy is likely to shift from the origins of the cell lines inhuman embryos to their fate as human regenerative and even reproductive materials.Insoo Hyun, PhDMedical Innovation Outside of Clinical Trials: Proceed with CautionRecently the U.S. Food and Drug Administration inaugurated a new policy allowing expanded access to investigational interventions by clinicians attempting to treatpatients outside the research context. For those interested in creating reliable platforms for a whole new generation of medical tools through genomics, gene transfer, andstem cell research, the FDA’s new policy holds many hazards. New models for local oversight of evidence-based medical innovation will be needed in order to avoid theuncontrolled and premature clinical exploitation of these platform technologies and still translate them successfully to the clinic.Jeremy Sugarman, MD, MPH, MAEthical Issues in Translational Research Involving Human Pluripotent Stem CellsThe clinical translation of human pluripotent stem cells may take several different paths including clinical translational research, clinical innovation, and the use of untestedor unproven interventions. Each of these translational pathways raises a unique set of ethical issues. Furthermore, there are distinct standards of practice and proceduralmechanisms for addressing the ethical issues inherent to each pathway. As such, it is essential that these differences be recognized to best protect not only the well-beingof patients, but also of the scientific enterprise as it seeks to understand the true value of stem-cell based interventions.PanelRoger H. Bertolotti, PhDJames Ellis, PhDDeborah A. Hursh, PhDEXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 31Program ScheduleScientific Symposium 1121:00 pm - 3:00 pmRoom: Marriott Ballroom Salon 1Barriers to HSC Gene TherapyCo-ChairsManuel Grez, PhD & Harry L. Malech, MDSpeakersMary C. Dinauer, MD, PhDNew Approaches for Marrow Conditioning in HSC Gene TherapyIn many genetic blood disorders, there is no selective advantage for hematopoietic stem cells following gene correction. Hence, in addition to expression of adequatelevels of the therapeutic protein, successful use of HSC gene therapy in these disorders will require efficient transduction, homing and engraftment of transduced HSC, aswell as cytoreduction of uncorrected HSC. It is highly desirable to develop effective conditioning regimens that reduce marrow content of uncorrected HSC yet minimizeexposure of patients to genotoxic agents and acute and long-term multiorgan toxicities. This talk will present new approaches for marrow conditioning for transplantationin HSC gene therapy, including more selective targeting of HSC in their niche.Luigi M. Naldini, MD, PhDExploiting and Antagonizing miRNA in Gene TherapyC. Anthony Blau, MDPharmacologically Regulated Cell TherapyHematopoietic stem cells (HSC) compete for the opportunity to contribute to various mature cell lineages in the blood, however little is known about the rules that governthis competition. Eight years ago, two dogs were transplanted with autologous CD34+ cells that had been transduced with an gammaretrovirus vector encoding greenfluorescent protein (GFP) and a conditionally activatable derivative of the thrombopoietin receptor (F36VMpl). Responses to F36VMpl signaling, elicited through administrationof a chemical inducer of dimerization (CID), were reported previously. Now long-term monitoring shows no spontaneous rises in GFP+ cells over time, suggestingthat F36VMpl is inert in the absence of CID. Stably higher frequencies of GFP+ B and T cells relative to other lineages suggests that CID administration within the first 18months post-transplantation generates stable increases in transduced lymphocytes, whereas only myeloid lineages responded when later courses of CID were administeredin one animal. Clonal tracking identified functionally distinct categories of hematopoietic stem cells: those that persisted and remained CID responsive, those that persistedbut were CID unresponsive, and those that did not persist.Christopher Baum, MDApproaches to Avoid Adverse Events in the Genetic Modification of Hematopoietic CellsAdverse events related to insertional mutagenesis or ectopic transgene expression may compromise the therapeutic prospects of gene therapy in the hematopoietic system.Over the past years, major progress has been made in the understanding of the underlying mechanisms, opening rational approaches to increase the therapeutic index. Wehave established sensitive nonclinical models, in transplanted C57BL/6J mice or using cultured cells, to reveal the transforming capacity of insertional activation of cellularproto-oncogenes such as Evi1 or Prdm16, and developed integrating gene vectors designed to reduce the risk of insertional transformation by altering the insertion patternand the expression cassette of the transgene. In a murine model of Mpl deficiency, major adverse events related to ectopic protein expression could be controlled bytranscriptionally targeted vectors. Two important principles emerge to ensure undisturbed long-term hematopoiesis from gene-modified cells. The first is the establishmentof polyclonal hematopoiesis using vectors with an untargeted integration profile and “physiological” transgene cassettes. The second is the generation of clonally definedhematopoiesis derived from induced pluripotent cells with genetic modification in bona fide safe harbours.Wednesday, May 19 th

32American Society of Gene & Cell TherapyProgram ScheduleWednesday, May 19 thScientific Symposium 1131:00 pm - 3:00 pmRoom: Maryland SuiteDelivery of Oligonucleotide TherapeuticsChairBruce Sullenger, PhDSpeakersLeaf Huang, PhDDeliver siRNA for Cancer TherapysiRNA can not fulfill its promise to become the next generation pharmaceutics unless it is efficiently delivered to the cytoplasm of the target cells. Membrane/core typenanoparticles with appropriate surface modification evade the reticuloendothelial system and enable high level accumulation of siRNA in the tumor cells. Recent effortfocuses on de-assembly of the nanoparticles and cargo release from the endosome. Specific examples of siRNA mediated therapy in animal models will be presented.Joseph DeSimone, PhDMicro- and Nano-Fabricated Particles for Therapeutics and VaccinesWe are employing top-down particle fabrication technologies adapted from the microelectronics industry to make highly uniform shape specific particles of controlledcomposition for use as therapeutics and vaccines. Strategies will be discussed for the intracellular release of various cargos and for selective targeting of particles.Steven F. Dowdy, PhDsiRNA Delivery: Tackling the 800 Pound GorillasiRNA induced RNAi responses have great potential to treat human disease, especially cancer and viral infections. However, siRNAs are negatively charged, 14,000 Daltonmacromolecules with no bioavailability to enter cells and siRNA cellular delivery remains a significant rate-limiting step for development of RNAi therapeutics. To addressthe siRNA delivery problem, we developed a Peptide Transduction Domain-dsRNA Binding Domain (PTD-DRBD) fusion protein. DRBDs bind siRNAs in a sequence-independentmanner that masks the negative charge, allowing for PTD-mediated siRNA delivery in vivo. PTD-DRBD fusion proteins begin to address the siRNA delivery problem witha high efficiency and low toxicity, biodegradable platform.Joshua Mendell, MD, PhDMicroRNA Replacement TherapiesMicroRNAs (miRNAs) are ~21-23 nucleotide RNAs that regulate the stability and translation of target messenger RNAs. We and others have demonstrated that dysregulatedexpression of miRNAs is a ubiquitous feature of cancer cells and specific miRNAs can act as oncogenes and tumor suppressors. More recently, we showed that dueto their ability to strongly inhibit tumorigenesis, select miRNAs represent potent and non-toxic anti-cancer therapeutic agents when delivered systemically. I will present ourlatest findings regarding the roles of miRNAs in cancer and other diseases and the therapeutic potential of miRNA delivery.Break3:00 pm – 3:30 pmEDUCATION SESSIONSThe goal of the ASGCT Education Program is to provide participants with a broad background and introduction to topics relevant to the field of gene and cell therapy.Education Sessions will be subdivided into two headings. “Topical Review” sessions will provide a broad perspective of an area of importance to the gene and cell therapycommunity such as major vector systems, specific target organs or diseases, and funding/regulatory issues. “Emerging Field Review” sessions will provide a broadperspective of a technological or scientific discipline that has recently become of great significance to ASGCT members.EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 33Program ScheduleEducation Session 1203:30 pm - 5:00 pmRoom: Virginia SuiteEmerging Field Review: Genomic Basis of Human DiseaseThis program will be presented by three established investigators at the NIH National Human Genome Research Institute and will highlight active research programs ofdirect relevance to the field of gene and cell based therapies. The topics to be covered include: 1) The Genomics Landscape Circa 2010, 2) The ClinSeq Project: PilotingGenome Sequencing for Research in Genomic, and 3) The NIH Undiagnosed Diseases Program.Wednesday, May 19 thChairPaul B. McCray, Jr., MDSpeakersEric D. Green, MD, PhDThe Genomics Landscape Circa 2010The Human Genome Project’s completion of the human genome sequence in 2003 was a scientific achievement of historic proportions. It also signified a critical transition,as this new foundation of genetic information started to be used in powerful ways by researchers and clinicians to tackle increasingly complex problems in biomedicine.Current efforts in genomics research are focused on using genomic data and technologies to acquire a deeper understanding of biology and to uncover the genetic basis ofhuman disease. Together, these pursuits are moving us down an exciting path towards genomic medicine and fulfilling the promise of a sequenced human genome.Leslie G. Biesecker, MDLarge Scale Sequencing and Hypothesis-Generating Clinical ResearchTo date, high-throughput DNA sequencing has been used to elucidate the complete sequence of various species’ genomes. In contrast, its application to clinically directedresearch has been minimal. It is postulated that this technology will be applied to clinical care in the future – such as for pre-symptomatic diagnoses of medical conditions,customization of preventive strategies, and determination of individuals’ pharmacogenetic profiles. The National Human Genome Research Institute (NHGRI) has a longtermgoal of developing the technology and infrastructure for performing large-scale medical sequencing (LSMS) for health research and, eventually, routine clinical care.Thus, at this time pilot studies are needed to start addressing some of the issues surrounding the development and implementation of LSMS in the clinical research setting.We have launched a pilot project, called ClinSeq, within the NHGRI intramural program. The objective of ClinSeq is to pilot approaches to the technical, medical,and genetic counseling issues related to LSMS by generating a large amount of sequence data from a set of participants. Unlike other projects that maintain anonymizedsamples, ClinSeq is being designed to maintain identified samples to allow us to implement an iterative clinical research strategy that over time will lead to return of individualresults to study participants. With this design we hope not only to contribute to the knowledge about susceptibility genes, but also to understand how to integratethis technology into clinical practice.William A. Gahl, MD, PhDThe NIH Undiagnosed Diseases ProgramThe NIH Undiagnosed Diseases Program (UDP) has as its goals to provide answers to patients with mysterious conditions that have long eluded diagnosis and to advancemedical knowledge about rare and common diseases. In the past two years, the UDP has received 2700 inquiries and 1100 medical records. Approximately 240 patientshave been accepted; a diagnosis has been obtained for 10-15% of patients seen. The application of state-of-the-art genetic analysis makes this program a model for theuse of genetics in the investigation of diagnostic dilemmas. One new disease has been discovered, along with unusual variants of known diseases. The Program alsoprovides insights into the current practice of medicine in the United States.

34American Society of Gene & Cell TherapyProgram ScheduleWednesday, May 19 thEducation Session 1213:30 pm - 5:00 pmRoom: Marriott Ballroom Salon 1Emerging Field Review: Regulatory RNAsAbout a decade ago, it became clear that RNA has a widespread, general role in gene regulation. At least part of this regulation is mediated through a mechanism termedRNA interference (RNAi). The first talk will discuss the basic principles of RNAi and the biology of the small RNA species which mediate RNAi. The discovery of RNAi hasopened up new avenues in genetic engineering which will be covered by the subsequent talks: Delivery of a small interfering RNA (siRNA) or an artificial microRNA(miRNA) with a specific sequence directed against an endogenous mRNA can result in potent knockdown of any gene of interest. Conversely, endogenous regulatoryRNAs can be exploited as an additional layer of regulation to restrict the expression of an exogenously introduced transgene to cells of a specific tissue origin, lineage ordifferentiation state. Finally, as miRNAs are increasingly being implicated in human disease, technologies that allow their manipulation (knockdown and overexpression)become relevant.Co-ChairsBernhard Rudolf Gentner, MD & Alfred Lewin, PhDSpeakersBrian D. Brown, PhDThe Biology and Application of Regulatory RNAsOver the past few years major advances have been made in understanding the action and mechanism of regulatory RNAs. These advances have helped to identify someof the important factors that influence microRNA and target interaction, which, in turn, is facilitating the improvement of technologies that utilize or target the microRNApathway, including RNA interference (RNAi). Here we will discuss some of the recent findings in regulatory RNA biology and how these findings are being applied.Ryan L. Boudreau, PhDRNAi-based Strategies for Silencing DiseaseWith a better understanding of endogenous miRNA biogenesis and gene silencing processes, scientists have devised strategies to co-opt the cellular RNAi machinery inorder to specifically silence various genes of interest. In this way, RNAi serves as a powerful molecular tool used to study gene function in biological processes and providesa novel strategy to treat a variety of diseases (e.g. dominant genetic disorders, cancer and viral invasion, among others). The application of RNAi as a biological ortherapeutic tool is primarily limited by our ability to introduce inhibitory RNAs into target cells or tissues. Inhibitory RNAs can be designed to mimic primary miRNA stemloops(artificial miRNAs), processed pre-miRNAs (short-hairpin RNAs or shRNAs) or mature miRNAs with perfect complementarity to their targets (small interfering RNAs orsiRNAs). This presentation will overview these RNAi vectors, delivery strategies, and highlight important results regarding RNAi vector safety.Bernhard Rudolf Gentner, MDHow to Study and Exploit microRNAs for Gene TherapyChromatin state and the presence of a particular set of transcription factors binding to the promoter sequence determines the transcription of a gene into mRNA. Morerecently, it has become clear that the mRNAoma is extensively subjected to negative regulation by a system involving hundreds of small RNA molecules, the so called“microRNAs”. Similar to the transcription factor complement, the “microRNAoma” is specific for tissues, lineages as well as cellular differentiation and activation states,offering an opportunity to exploit this endogenous layer of regulation to tune the expression of engineered DNA. microRNA regulation has proved a powerful tool toshut down expression in entire tissues like hematopoietic cells, hepatocytes, muscle, and nervous tissue, and thus control transgene immune responses, limit off-targettransgene toxicity and even change the tropism of oncolytic viruses. Another emerging application for microRNA regulated expression cassettes is stem cell research andtherapy. microRNAs allow to dissect different stages of differentiation, from the bona fide stem cell down to the progeny of different lineages. Applications for iPS cells andhematopoietic stem cells will be discussed. A potential side effect of exploiting miRNA regulation is the saturation of miRNA activity and thus deregulation of natural miRNAtargets. Guidelines how to avoid miRNA saturation will be presented.EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 35Program ScheduleEducation Session 1223:30 pm - 5:00 pmRoom: Wilson ABCTopical Review: Cell TherapyChairEdwin M. Horwitz, MD, PhDSpeakersEdwin M. Horwitz, MD, PhDFundamentals of Cell TherapyPeter Johnston, MD, FACCStem Cell Therapy for the HeartNearly 6 million people in the United States suffer from heart failure. This burden of disease has driven interest in stem cell therapy for the heart in the hope that dysfunctionalmyocytes and vasculature might be repaired or replaced. Clinical trials to date have explored the use of various skeletal, bone marrow-derived, endothelial, andendogenous cardiac precursor cells for cardiac repair. Along with much promise, there remain many questions about not only the optimal type of cell, but also the timingand delivery method necessary to achieve the maximal therapeutic benefit.Dao Pan, PhDCell and Gene Therapy for CNS Abnormalities in Lysosomal Storage DisordersLysosomal storage diseases (LSD) are a group of ~40 inherited metabolic disorders with a combined incidence of 1 in 1500 to 7000 live births. More than 70% of allLSD affects the central nervous system (CNS). Bone marrow stem cell transplantation has been shown to ameliorate many visceral symptoms in some LSD patients;however CNS disease associated with LSD remains as a major challenge. Here we will discuss experimental and preclinical studies toward new therapeutic strategies,including stem cell-based brain transplantation therapies, hematopoietic stem cell gene therapies, and CNS-targeted gene therapies. Issues that are pertinent to theirpotential translational applications will also be addressed.Wednesday, May 19 thEducation Session 1233:30 pm - 5:00 pmRoom: Thurgood Marshall WTopical Review: Gene Therapy for Eye DiseasesRecent successes in viral vector-based gene therapy clinical trials underscore the potential of gene therapy as a means to provide definitive solutions for currently incurableocular diseases. This session will focus on the basic biology and vector development for ocular diseases. In addition, it will provide recent updates on novel strategies invector design, as well as the status and prospects of gene therapy clinical trials for ocular diseases.Co-ChairsPeter A. Campochiaro, MD & Tal Kafri, PhDSpeakersBill Hauswirth, PhDAAV Vector Considerations for the RetinaConsiderations for AAV vectors intended for transducing cells of the retina include 1) the anatomical site of vector injection, 2) the vector serotype, 3) the size of thevector genome, 4) the strandedness of the vector genome and 5) the ability of novel AAV vectors to penetrate retinal tissue. Each issue will be discussed in the context ofgene-based therapies for degenerative retinal diseases.John G. Flannery, PhDEvolution of AAV Vectors for Ocular Gene Therapy

36American Society of Gene & Cell TherapyProgram ScheduleWednesday, May 19 thPeter A. Campochiaro, MDOverview of Gene Therapy for Ocular DiseasesThe potential of ocular gene therapy has been demonstrated in animal models and early clinical trials. Proof-of-concept has been provided for gene replacement of mutatedgenes in inherited retinal degenerations by 3 clinical trials demonstrating improved visual function by replacement of the RPE65 gene in patients with Leber’s congenitalamaurosis. Studies are being considered for X-linked retinoschisis and Stargardt’s disease. A trial in which an antiangiogenic protein was delivered with an adenoviralvector for neovascular age-related macular degeneration (AMD) has shown good safety and some suggestion of biological activity. A trial in which a vascular endothelialgrowth factor binding protein is delivered with an AAV vector in patients with neovascular AMD has recently started. Preclinical studies suggest that gene delivery of neurotrophicfactors or antioxidant proteins may be considered for retinal degenerations. Thus early clinical trials suggest several promising avenues for ocular gene therapy.Education Session 1243:30 pm - 5:00 pmRoom: Maryland SuiteTopical Review: Stem Cell BasicsIn order for stem cells to fulfill their potential as viable cell transplant/gene transfer therapeutics, it will be necessary to understand the process of stem cell self-renewalto obtain sufficient cell numbers to be applicable for transplant. Additionally, the genes/factors involved in differentiating these pluripotent cells down specific lineagepathways will also be crucial in the development of a transplantable therapeutic. The speakers in this session will address these important issues that not only providefurther insight into organ and tissue development but also open up therapeutic avenues of practical application of these cells in regenerative medicine.ChairWilliam F. Goins, PhDSpeakersG. Ian Gallicano, PhDStem Cells: Past, Present, FutureThe idea of stem cell based therapies is particularly prevalent in the fields of diabetes, cardiac and neurological disorders. However, while the field of stem cell therapiesmay be relatively new, the road for stem cell research has been long and winding. Understanding hoe the evolution of the stem cell field has led to its current state isnot only interesting, it can serve as a powerful tool for predicting its future. Consequently, this presentation will focus on the basic evolution of stem cells and their use intherapies.David F. Stroncek, MDGene and MicroRNA Expression in Human Embryonic Stem CellsGlobal gene expression analysis has been used to identify factors responsible for the pluripotency of human embryonic stem (hES) cells. Most genes expressed by hES areinvolved with RNA post-transcriptional modification, DNA replication, recombination and repair, RNA Damage repair, cell cycle, and cell growth and proliferation. Transcriptfactors are among the most highly expressed hES genes. Studies focusing on specific genes found that the transcription factors OCT4, NANOG and SOX2 are important inhES development and pluripotency. Transcription factors likely interact with chromatin remodeling factors and histone modifying enzymes to modulate chromatin conformation.The knockout of dicer in hES, a nuclease critical in microRNA generation, compromises hES cell proliferation and differentiation and demonstrates an important rolefor microRNA in hES cells. MicroRNA in the miR-302 and miR-520 clusters are expressed in hES cells and may contribute to chromatin structure modifications.Ming Zhan, PhDComputational Biology Studies to Decipher Molecular Mechanisms Controlling Embryonic Stem Cell PluripotencyComputational biology has played a significant role in investigation of embryonic stem cells (ESCs). In this presentation, I will describe comparative genomics andcomparative transcriptomics studies conducted on ESCs and genetic regulatory network analysis of ESCs through mathematical modeling. All the studies contribute to asystems understanding of molecular mechanisms controlling ESC self-renewal and differentiation.Break5:00 pm – 5:30 pmEXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 37Program ScheduleEducation Session 1305:30 pm - 7:00 pmRoom: Marriott Ballroom Salon 1Emerging Field Review: Progress Towards Using ES/iPS Cells for Regenerative MedicineThe excitement over embryonic stem cells and induced pluripotent stem cells is that they are a potential source of cells for tissues in which tissue specific stem cells haveeither not been identified, not easily isolated, or not easily expanded. That pluripotent stem cells can now be generated from somatic cells, without the destruction of anembryo, removes a major ethical barrier to their use. Nonetheless, a continued barrier to the translation of pluripotent stem cells to clinical use is to expand and differentiatethem in both a safe and quantitatively sufficient manner that they can be used for tissue specific regenerative medicine applications. This educational session willfocus on the progress that has been made in generating sufficient numbers of safe tissue specific cells towards this end.Wednesday, May 19 thChairMatthew H. Porteus, MD, PhDSpeakersRonald D.G. McKay, PhDElias T. Zambidis, MD, PhDGeneration of HSC and Red Blood Cells from Normal and Hemoglobinopathic iPSCEvan Y. Snyder, MD, PhD, FAAPCross-Talk and Developmental Programs in Stem Cell Biology – A Key to Regenerative MedicineEducation Session 1315:30 pm - 7:00 pmRoom: Maryland SuiteEmerging Field Review: Targeted IntegrationUncontrolled insertion of foreign DNA into the human genome may have deleterious consequences, and is a serious safety concern in the clinical application of genetherapy. New molecular tools are being developed to target transgene integration to specific sites in the genome and increase the frequency of homologous recombination,with the purpose of achieving gene correction or replacement in the original genomic environment. These advances include the use of Zn-finger nucleases and homingendonucleases, and the delivery of homologous recombination cassettes by viral and non-viral vectors. They will be discussed in the context of developing better and safergene transfer technology.ChairFulvio Mavilio, PhDSpeakersJ. Keith Joung, MD PhDEngineered Zinc Finger Nucleases for Targeted Genome ModificationEngineered zinc finger nucleases (ZFNs) form the basis of a broadly applicable approach for inducing targeted alterations with high efficiency in human and other mammaliancells. This session will provide an introduction to this important technology by: (1) discussing methods for engineering customized ZFNs including OligomerizedPool ENgineering (OPEN) and modular assembly; (2) describing how ZFNs have been used to introduce knockout mutations, insertions and other specific alterations vianon-homologous end-joining and homologous recombination; and (3) considering future experiments and goals for advancing the use of ZFNs for therapeutic and researchapplications.Andrew M. Scharenberg, MDHoming Endonucleases as Tools for Targeted IntegrationThe idiosyncratic nature of side effects resulting from random integration of promoter/gene cassettes in the context of viral vector-mediated gene therapy has led toincreasing interest in targeted integration as an alternative approach. A promising methodology for targeted integration involves application of rare cleaving nucleases toinduce site specific homologous recombination. Homing endonucleases are an important class of rare cutting nucleases whose potential applications in targeted integrationare only now emerging. Homing endonuclease biology, properties, engineering, and applications in targeted integration will be reviewed.

38American Society of Gene & Cell TherapyProgram ScheduleWednesday, May 19 thDavid W. Russell, MD, PhDAAV-Mediated Gene TargetingAAV vectors efficiently recombine with homologous chromosomal sequences in mammalian cells. Up to 1% of the entire cell population exposed to vector particlesundergoes gene targeting under optimal conditions. Insertions, deletions and substitutions can all be introduced at precise chromosomal locations with high fidelity. Thetechnique works well in many cell types, including transformed cell lines, stem cells, and even in vivo in murine hepatocytes. Importantly, the gene targeting occurswithout genotoxicity and endonucleases are not required to obtain high targeting frequencies.Education Session 1325:30 pm - 7:00 pmRoom: Thurgood Marshall WTopical Review: Gene Delivery to the HeartHeart disease is one of the leading causes of morbidity and mortality worldwide. While molecular causes are known for many heart diseases, it requires effective heartgene delivery methods to translate these findings into therapy. Because of the dynamic nature of the heart physiology and the unique anatomic location, cardiac genetransfer has been a great challenge. Significant progress has been made over the last few years. In this session, a historical overview of heart gene transfer will be provided.Considering the importance of the large animal model in translational medicine, special emphasis will be given to cardiac gene delivery in the canine and porcinemodels.ChairDongsheng Duan, PhDSpeakersDongsheng Duan, PhDOverview of Heart Gene Transfer in MiceEfficient cardiac gene transfer holds great promise in treating heart diseases, a major health threat worldwide. Over the last decades, tremendous progresses have beenmade in delivering the marker and/or therapeutic genes to the mouse heart. This presentation will provide a historic review of the literature and an update of the currentdevelopments.Roger J. Hajjar, MDGene Therapy for Heart Failure: New Targets and New VectorsDespite the proliferation of therapies, congestive heart failure remains a progressive disease where a desperate need for innovative rather than incremental therapies toreverse the course of ventricular dysfunction. Recent advances in understanding the molecular basis of myocardial dysfunction, together with the evolution of increasinglyefficient gene transfer technology; have placed heart failure within reach of gene-based therapies. One of the key abnormalities in both human and experimental HF isa defect in sarcoplasmic reticulum (SR) function, which is responsible for abnormal intracellular Ca2+ handling. Restoring SERCA2a levels has been shown to improvefunction, metabolism and/or survival in a number of experimental models of heart failure. Over the last ten years we have undertaken a program of targeting importantcalcium cycling proteins in experimental models of heart by somatic gene transfer. This has led to the completion of a first-in-man phase 1 clinical trial of gene therapy forheart failure using adeno-associated vector (AAV) type 1 carrying SERCA2a. In this Phase I trial, there was evidence of clinically meaningful improvements in functionalstatus and/or cardiac function which were observed in the majority of Neutralizing antibody negative patients at various time points. The safety profile of AAV genetherapy along with the positive biological signals obtained from this phase 1 trial has led to the recent completion of a phase 2 trial of AAV1.SERCA2a in NYHA class III/IV patients.Charles R. Bridges, MD, ScDMethods for Cardiac Gene DeliveryThis presentation will review the available methods of cardiac vector mediated gene delivery including those in use in current clinical trials. Methods considered will includeintracoronary injection, intramuscular injection, pressurized coronary venous retroinfusion, and cardiopulmonary bypass-mediated techniques. The relative strengths andweaknesses of these delivery methods will be discussed with reference to efficiency of transfection, cardiac versus collateral organ specificity and relative propensity toinduce a T-cell mediated immune response.EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 39Program ScheduleEducation Session 1335:30 pm - 7:00 pmRoom: Virginia SuiteTopical Review: Immunotherapy of CancerThe immune system can be properly modified to eradicate cancer. Currently, effector molecules, such as monoclonal antibodies and cells such as tumor-reactive lymphocytes,are able to selectively target and eliminate tumors, may be isolated and/or engineered. The potency of cellular adoptive immunotherapy has been revealed bypersistent and complete clinical responses obtained with by the transfer of allogeneic T lymphocytes in the context of allogeneic hemopoietic cell transplantation (allo-HSCT) and by the transfer of autologous tumor specific cytotoxic T lymphocytes (CTLs) in cancer patients. Major hurdles limiting adoptive T cell therapy relate to toxicity(ie: graft-versus-host disease-GvHD in allo-HSCT), feasibility and efficacy (ie: difficulty in expanding rare, high-avidity tumor-specific CTLs). Gene transfer technologies mayallow to overcome all these hurdles. The transfer of tumor-specific TCR or chimeric antigen receptors (CARs), confers tumor-specificity and activity to autologous T cells.The transfer of a suicide gene into allogeneic lymphocytes allows to tame toxicity of allogeneic lymphocytes. In this session, we will discuss clinical results, challenges andadvances recently made to improve the potency and specificity of adoptive immunotherapy with genetically modified lymphocytes to treat cancer.ChairChiara Bonini, MDSpeakersRichard A. Morgan, PhDUsing Engineered T Cells for the Treatment of CancerAdoptive cell transfer (ACT) using anti-tumor antigen reactive T cells has proven to be a useful strategy for the treatment of metastatic melanoma, with objective responserates of up to 72%, with 16% of patients rendered disease free. These studies involved the extraction and ex-vivo expansion of naturally occurring tumor infiltratinglymphocytes (TIL). Only one-half of patients are able to receive this therapy due to lack of harvestable tumors, inability to grow TIL, or a lack of cellular reactivity. Recentstrategies aimed at broadening ACT involve the use of chimeric antigen receptors (CAR) or T-cell receptor (TCR) genes specific for tumor associated antigens and the use ofviral vectors to transduce these genes into peripheral blood lymphocytes. TCR gene therapy has been applied with some success in recent trials targeting MART-1, gp100and NY-ESO-1. CAR gene therapy trials are also showing promising results in protocols targeting CD19+ lymphomas. Efforts aimed at improving the response rate andminimizing on-target toxicity are in progress.Gianpietro Dotti, MDCar-Based Gene Transfer in T LymphocytesExpression of a transgenic “T-body” or “chimeric antigen receptor” (CAR) in human T lymphocytes combines the specificity of an antibody with the homing and target-celldestruction capabilities of T cells. This technology was first described 15 years ago, and after significant improvements in gene transfer technologies and better understandingof immunological pathways is now reaching a critical phase of clinical evaluation. In this presentation we will summarize the concept of CAR-based immunotherapy,describe the steps accomplished, and outline the future progress we need to make if this approach is truly to improve cancer immunotherapy.Chiara Bonini, MDT-Cell Based Gene Therapy in Hematopoietic Stem Cell TransplantationThe potency of cellular adoptive immunotherapy for the treatment of cancer has been clearly revealed by the persistent and complete clinical responses observedin patients undergoing allogeneic hematopoietic stem cell transplantation (allo-HSCT) followed by the adoptive transfer of donor T lymphocytes. However, severalhurdles remain to be overcome before adoptive immunotherapy can become a broadly applicable therapeutic approach to treat cancer, and gene transfer approachesrepresent ideal solutions to overcome these hurdles. In allo-HSCT, most of the antileukemic potential resides in alloreactivity towards patient-specific antigens, such asminor and major histocompatibility antigens, by donor lymphocytes. Unfortunately, alloreactivity is also responsible for the most serious and frequent complication ofallo-HSCT: the Graft-versus-Host-Disease (GvHD). The risk of GvHD increases with the level of HLA disparity between host and donor, and leads to impaired quality oflife and reduced survival expectancy, particularly in patients transplanted from HLA-mismatched donors. Gene transfer technologies are promising tools to manipulatedonor T cell immunity to enforce the graft-versus-tumor (GvT) effect, to promote a functional post-transplant immune reconstitution (graft-versus-infection-GvI) and toprevent or control GvHD. To this purpose, several cell and gene transfer approaches, have been investigated at pre-clinical level, and are being implemented in clinicaltrials. The majority of these approaches, based on negative or positive selection of specific T cell subpopulations, aim at reducing the repertoire of donor lymphocytesinfused with or after the graft, so to prevent alloreactivity. In contrast, suicide gene therapy aims at a selective control of GvHD in treated patients, thus permittingthe full exploitation of alloreactivity against cancer cells. In a phase I-II clinical trial enrolling 54 pts undergoing haploidentical HSCT, we showed that the transfer of asuicide gene into donor lymphocytes, allows to provide rapid and effective immune reconstitution, and control of GvHD. By taming the toxicity of allo-HSCT the suicidegene approach renders haploidentical HSCT a feasible, safe and more effective option for cancer patients of all ages. Cell and gene therapy approaches currentlyimplemented for a safe exploitation of donor immunity against cancer, in the context of allo-HSCT will be discussed.Wednesday, May 19 th

40American Society of Gene & Cell TherapyProgram ScheduleWednesday, May 19 thEducation Session 1345:30 pm - 7:00 pmRoom: Wilson ABCTopical Review: Pre-existing Immunity to Gene Transfer VectorsMany viral gene therapy vectors are derived from parent viruses that are present in the human population. Pre-existing immunity to such vectors in form of antibodies andmemory B and T cell responses can severely hamper gene transfer in humans. This session will review basic aspects of B cell biology, prevalence of antibodies to DNAviruses (AAV and adenovirus) in the human population, and CD8+ T cell responses to AAV capsid in humans.ChairRoland W. Herzog, PhDSpeakersMichael Cancro, PhDThe Persistent Problem of B Cell MemoryPrimary and memory/effector B cell subsets occupy distinct anatomic and homeostatic niches. Despite growing understanding of the factors governing pre-immune B celllifespan and homeostasis, the factors regulating antigen-experienced pools – including memory B cells and plasma cells – remain less clear. These likely include membersof the BLyS family of cytokines and receptors, as well as molecular interactions between B lineage cells and survival-promoting stromal elements.Luk H. Vandenberghe, PhDB-cell Immunity to Viral VectorsMany of the commonly used vectors for gene therapy application are based on viruses that are endemic in the human population. Therefore, pre-existing immunity mayalter the safety and efficacy of gene therapy strategies. In addition, repeated administration of the vector may be required for certain therapeutic applications which willalso need to overcome the hurdle of pre-existing immunity. Here, we will focus on the breadth and implication for gene transfer of the presence and prevalence of antibodiesto Adeno and Adeno-Associated viruses in humans and animal models.Katherine A. High, MDHuman T Cell Responses to AAV CapsidStudies in healthy donors have shown antigen-specific memory CD8+ T cells to AAV capsid in a substantial portion of the human population. We have hypothesized thatthese cells may expand on re-exposure to AAV capsid through administration of AAV vectors. Studies in several AAV gene transfer trials have shown that vector administrationis followed by development of positive responses on IFN-g ELISPot assays. We have shown that capsid-specific CD8+ T cells can lyse AAV-transduced hepatocytes in anin vitro assay, but the clinical and biological correlates of a positive IFN-g ELISPOt response are still under investigation. A clear understanding of capsid antigen processingand presentation, and of T cell responses to AAV, will be key to optimal application of the vector.Exhibit Hall Open & Welcome Reception7:00 pm – 9:00 pmRoom: Exhibit Hall CEXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 41Program ScheduleThursday, May 20George Stamatoyannopoulos Lecture 2008:00 am - 9:15 amRoom: Marriott Ballroom Salons 1, 2 & 3George Stamatoyannopoulos LectureChairBarrie J. Carter, PhDSpeakerThursday, May 20 thHal E. Broxmeyer, PhDUnderstanding and Enhancing Stem/Progenitor Cell Function and EngraftmentThere are a number of cytokines, cytokine receptors, cell surface proteins, and intracellular molecules that regulate hematopoietic stem (HSC) and progenitorcell (HPC) function. Amongst these are the chemokine, stromal cell derived factor-1 (SDF-1/CXCL12), its receptor, CXCR4, the cell surface protein CD26/Dipeptidylpeptidase IV, which truncates and inactivates specific cytokines, the Rapamycin sensitive m-TOR pathway, and the sirtuin family member, SIRT1. Effortsare underway to modulate these proteins/molecules for enhanced engraftment of HSC/HPC and accelerated hematopoiesis.Exhibit Hall Coffee Social9:15 am – 10:30 amRoom: Exhibit Hall C

42American Society of Gene & Cell TherapyProgram ScheduleThursday, May 20 thScientific Symposium 21010:30 am - 12:30 pmRoom: Marriott Ballroom Salons 2 & 3Clinical TrialsChairR. Jude Samulski, PhDSpeakersSteven A. Rosenberg, MD, PhDCancer Immunotherapy Using Genetically Modified T CellsPatients with advanced cancer have been treated by the adoptive transfer of autologous T cells transduced with retroviral vectors encoding antitumor T cell receptors.Objective cancer regressions have been seen in patients with metastatic melanoma receiving cells targeting melanoma/melanocyte differentiation antigens and in patientswith synovial cell sarcoma who received cells targeting the NY-ESO-1 cancer-testes antigen. Clinical trials have also begun targeting CD19 on lymphomas and targetingcarcinoembryonic antigen on colorectal cancers.Ian MacLachlan, PhDA Phase I Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Lipid Nanoparticle ApoB siRNA (ApoB-SNALP) in Hypercholesterolemic SubjectsStabilized nucleic acid lipid particles (SNALP) are a modular lipid nanoparticle delivery platform developed for the delivery of nucleic acid based drugs. Two SNALP productcandidates, containing siRNA payloads, are currently being evaluated in clinical trials in oncology and metabolic indications. By the end of 2010 we expect that as many asfive SNALP based product candidates will be in clinical trials. SNALP containing siRNA that potently silence the conventionally non-druggable target, apolipoprotein B, havebeen evaluated in a Phase 1 clinical trial in hypercholesterolemic subjects. Early results, including the elucidation of previously cryptic immune stimulatory activity associatedwith the chemically modified siRNA payload, will be presented.Bill Hauswirth, PhDLeber Congenital Amaurosis (LCA) Gene Therapy Clinical TrialResults and implications of a recently initiated AAV vector clinical trial for LCA2 (recessive RPE65 mutations) will be discussed. LCA2 patients received 150ul (5.9 exp10vector genomes) of GMP grade AAV2-CBA-hRPE65 vector subretinally and their visual function then followed periodically over the next 18 months. No adverse eventswere noted for any patient, all demonstrated substantial and significant improvement in light sensitivity, up to 63,000 times better that pretreatment baselines, and somedeveloped a new preferred locus of visual fixation centered on the area of treated retina.R. Jude Samulski, PhDDesigning AAV Vectors for Translational Studies: Update on DMD Phase 1 TrialInitial AAV vectors for clinical studies have been derived from natural isolates. We have engineered and tested in Phase 1 DMD study chimeric vector derived from type 1and type 2. Outcome of these studies and next generation of DMD viral vectors suited for efficient gene delivery will be described and pre-clinical data presented.Scientific Symposium 21110:30 am - 12:30 pmRoom: Marriott Ballroom Salon 1Tissue Specific Stem CellsChairCarolyn Lutzko, PhDSpeakersPamela Itkin-Ansari, PhDDevelopment of Cell Based Therapies for DiabetesThe presentation will address a range of issues regarding development of pancreas specific stem cell based therapies. First, evidence for stem cells in the adult pancreas andsuggested methods for improved identification of such populations will be discussed. Strategies for the recruitment and differentiation of tissue specific stem cell populationsin vitro and in vivo will also be addressed. Finally, because insulin producing β-cells are cell autonomous (in contrast to many cell targets, e.g. neurons and cardiomyocytes),they are amenable to novel transplantation and regeneration approaches which will be presented.EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 43Program ScheduleMarkus Grompe, MDHepatobiliary Stem/Progenitor CellsCarolyn Lutzko, PhDDeveloping Stem Cell Based Therapies for Lung Disease: Bringing Genes to Lung Stem Cells and Stem Cells to the LungThis presentation will focus on different strategies for developing stem cell based therapies for lung diseases. One strategy that will be discussed is the genetic modificationof endogenous lung progenitor cells during development. This presentation will also discuss progress on the differentiation of lung progenitor cells from pluripotent stemcells in vitro.Mervin C. Yoder, MDAre Endothelial Progenitor Cells Derived from the Endothelial Lining of Blood Vessels?Circulating endothelial progenitor cells (EPC) have been reported to play important roles in vascular repair and regeneration and are altered in concentration in patientswith arthritis, diabetes, cancer, and cardiovascular disease. No unique marker exists to identify this cell. Indeed, evidence suggests that numerous cell types participate inneoangiogenesis under the term EPC. We will review recent literature that suggests the local endothelial lining to be a major site of vascular repair.Scientific Symposium 21210:30 am - 12:30 pmRoom: Virginia SuiteCell and Gene Therapy Approaches for Genetic Diseases: Progress and ChallengesChairCharles P. Venditti, MD, PhDSpeakersNathalie Cartier-Lacave, MDGene Therapy for AdrenoleukodystrophyWe report results of the first clinical trial using an HIV vector to correct hematopoietic stem cells (HSC) in adrenoleukodystrophy, a severe degenerative disease of thecentral nervous system. Three children received autologous corrected HSC after full myeloablative conditionning. Up to 36 months after treatment, stable expression wasdemonstrated in peripheral blood leukocytes and bone marrow CD34+ cells, with polyclonal integration of the lentiviral vector. Neurological outcome was comparable tothat observed after allogeneic transplantation. These results demonstrate that lentiviral vectors are promising tools for gene transfer into hematopoietic stem cells in theabsence of selective advantage.Alessandra Biffi, MDHSC Gene Therapy for Metachromatic and Globoid Leukodystrophies: The Next Trials for Inherited Neurological DisordersWe are implementing a gene therapy approach based on the transplantation of gene corrected hematopoietic stem cells (HSC) for the treatment of severe forms ofLysosomal Storage Disorders (LSD) lacking efficacious and safe alternative therapeutic opportunities. To this goal, we exploit the unique features of lentiviral vectors (LV),which are prime candidates for HSC gene transfer. Indeed, by using LV for HSC gene correction, we proved the therapeutic potential and safety of HSC gene therapy in themurine model of metachromatic leukodystrophy (MLD), a severe dysmyelinating LSD. According to these promising results, HSC gene therapy for MLD has now reachedclinical testing. Similarly, an advanced LV design allowed rendering HSC gene therapy a feasible and efficacious approach to be further developed also for globoid cellleukodystrophy, on which we obtained very promising evidences in the disease model.Ronald D.G. McKay, PhDRobert D. Steiner, MDCNS Transplantation of Neural Stem Cells in Neuronal Ceroid Lipofuscinoses: Phase I Trial ResultsInfantile and late-infantile neuronal ceroid lipofuscinosis (INCL and LINCL) are universally fatal neurodegenerative lysosomal storage disorders caused by palmitoyl proteinthioesterase and tripeptidyl peptidase deficiency, respectively. A Phase I trial of human central nervous system stem cells (HuCNS-SC®) was conducted in subjects withINCL and LINCL. This study represents the first US FDA authorized use of human neural stem cells for clinical testing. The primary goal of the trial was to evaluate thesafety of direct CNS delivery of HuCNS-SC, the immunosuppression regimen, and the surgical technique. Six children underwent HuCNS-SC transplantation;. the studyresults to be presented will include adverse events as well as the neurological, seizure, EEG, radiological, neuropsychological, functional, and quality-of-life measuresassessed at frequent intervals post-transplant, as well as evidence of engraftment.Thursday, May 20 th

44American Society of Gene & Cell TherapyProgram ScheduleThursday, May 20 thScientific Symposium 21310:30 am - 12:30 pmRoom: Delaware SuiteHow Viruses Cause Disease: Implications for Vector and Vaccine DevelopmentChairRoberto Cattaneo, PhDSpeakersLynn W. Enquist, PhDResponse of PNS Neurons to Herpesvirus InfectionMost alpha herpesviruses are pantropic, neuroinvasive pathogens that establish a reactivateable, latent infection in the peripheral nervous system of their natural hosts.Various manifestations of herpes disease rely on extent and direction of the spread of infection between the surface epithelia and the nervous system components thatinnervate that surface. One aspect of such controlled spread of infection is the capacity for synaptically defined, transneuronal spread, a property that makes alphaherpesviruses useful tools for determining the connectivity of neural circuits and gene delivery. Spread of infection among neurons involves long distance travel of virioncomponent in axons. I will discuss our recent work on the response of cultured PNS neurons to infection.Jeffrey Bergelson, MDCell Biology of Virus EntryViruses need cells, and they have evolved to manipulate cellular processes at many stages of their life cycle. In a number of cases, virus-induced signals are needed toprepare the cell for virus entry and infection. I will discuss several examples of viruses— including adenoviruses and picornaviruses— that use receptor-mediated signalsto initiate the entry process.Bernard Moss, MD, PhDPoxvirus Replication and Pathogenesis: Implications for Vector and Vaccine DevelopmentThe ability of vaccinia virus to infect most cells provides an important advantage for their extensive use as an expression vector and as an oncolytic agent. We have shownthat an unprecedented number of viral proteins are required for the membrane fusion step, which can occur either at the plasma membrane or in endosomes. These 12proteins are associated in a complex and conserved in all members of the poxvirus family.Roberto Cattaneo, PhDThe Force Behind Targeting: How the Receptor-Triggered Membrane Fusion Mechanism of Measles Virus WorksMeasles is one of the most infectious viruses, and its portable entry system has become the paradigm for targeting oncolysis and therapeutic gene delivery. While thissystem is strictly regulated, the mechanism triggering fusion of the viral envelope with the plasma membrane was unknown. We show that re-alignment of the subunits ofthe viral attachment protein (H) is the trigger, and that force exerted at an appropriate location on the H-dimer unlocks the trigger at the plasma membrane, just as lowpH or proteases trigger endosomal membrane fusion in other viral entry systems.Scientific Symposium 21410:30 am - 12:30 pmRoom: Maryland SuiteGene and Cell Therapeutic Approaches for Musculo-Skeletal DiseasesCo-ChairsPaula Clemens, MD & Alan J. Nixon, DVM, MSSpeakersEdward M. Schwarz, PhDRevitalizing Structural AllograftsTo the end of a tissue-engineering solution for large segmental defects in bone caused by trauma or tumors, we proposed rAAV-coated allografts, which introduce angiogenic,osteogenic and osteoclastogenic factors into the healing environment to stimulate vascular ingrowth, bone formation and remodeling of the necrotic tissue. Here Iwill describe the molecular biology of this technology, its methodology and application in mice, and the translational outcome measures that have been developed to proveefficacy in large animals and humans in which torsional biomechanical strength is the primary outcome measure.EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 45Program ScheduleSteven C. Ghivizzani, PhDGene Therapy for AchondroplasiaAchondroplasia is the most common form of short-limbed dwarfism and is caused by a specific mutation in the transmembrane portion of fibroblast growth factor receptor3 (FGFR3), a negative regulator of growth and maturation in growth plate chondrocytes. This “gain of function” mutation causes enhanced signaling from FGFR3, leadingto reduced growth in bones that grow by endochondral ossification. Using gene delivery, we have been exploring the utility of systemic delivery of a secreted FGFR3variant as a means to titrate circulating FGFR3 ligands and, thereby, reduce aberrant FGFR3 signaling to rescue bone growth. Our results thus far in explant culture and ina mouse model of achondroplasia have been highly encouraging, and indicate that a related post-natal treatment approach may be viable in humans.Joel R. Chamberlain, PhDSystemic Delivery of RNAi Therapeutics for Treatment of Myotonic DystrophyDominant genetic diseases pose a particular challenge for therapy since the disease-causing cell product must be eliminated. We have chosen an RNA interference-basedapproach to target toxic mRNA that causes myotonic dystrophy. We show that disease pathology in the transgenic HSALR mouse model of DM1 is mitigated by systemicapplication of AAV6 carrying an HSA-targeted RNAi expression cassette. Aspects of systemic delivery and endogenous RNAi pathway effects will be presented in the contextof therapeutic development. These studies highlight the potential of RNAi as a therapy for dominant muscle disease and for other diseases where body-wide therapeuticRNAi distribution is required.Carmen Bertoni, PhDEnhanced Cell-Mediated Regenerative Approaches to DMD Using RNA InterferenceMany of the diseases affecting muscle are distinguished by the impaired ability of muscle progenitor cells to fuse and form new fibers and the inability of the existingfibers to maintain normal homeostasis. Among those, Duchenne muscular dystrophy (DMD) is the most severe and is caused by lack of dystrophin expression. The loss ofmuscle mass and strength typically seen in DMD patients is thought to be attributed to the progressive atrophy and loss of individual muscle fibers, which is concomitantto the accumulation of fibrotic and fat tissues in skeletal muscles. The mdx mouse has been instrumental in determining the potential beneficial effects of some of thetherapeutic approaches currently under development for DMD. We have used High Throughput Screen (HTS) to identify modulators of muscle progenitor cells fusionin vitro and screened several siRNA libraries in order to identify genes that play active role during terminal differentiation. Secondary and tertiary screens were used toconfirm the effects of RNAi on wild type or mdx muscle cultures and to select for candidate hits that significantly enhance myotube size.Transplantation of wild type muscleprogenitor cells undergoing silencing of the genes identified by HTS enhanced the ability of those cells to repair skeletal muscles of mdx/nude mice and resulted in asignificant increase in dystrophin expression. Direct intramuscular injection of a lentiviral vector expressing shRNAs of those genes was also shown to dramatically improveregeneration of injected muscles. These studies advance cell-mediated regenerative approaches to DMD and may enable us to identify treatments capable of slowing downprogressive muscle wasting characteristic of many neuromuscular disorders.Thursday, May 20 thScientific Symposium 21510:30 am - 12:30 pmRoom: Wilson ABCNovel Cell and Gene Therapy Interventions for the LungChairBruce A. Bunnell, PhDSpeakersDaniel Weiss, MD, PhDRecent Advances in Gene and Cell Therapies for Lung DiseasesGene and cell therapy approaches for lung diseases continue to rapidly develop. Progress has been made in vector development and several notable advancements havebeen made over the past year with use of gene transfer approaches for lung cancer. In parallel, cell therapy approaches for lung diseases have broadened and includestudies of ex vivo lung regeneration using state of the art bioengineering approaches as well as increasing appreciation of immunomodulatory effects of adult mesenchymalstem cells in the lung. Most notably, progress has been made in clinical trials of cell therapies for both pulmonary hypertension and for chronic obstructive pulmonarydisease. The introductory comments and subsequent presentations in this session will highlight these advances.

46American Society of Gene & Cell TherapyProgram ScheduleThursday, May 20 thPaul B. McCray, Jr., MDLentiviral Vector Development for Prevention and Treatment of Cystic Fibrosis Lung DiseaseThis talk will provide an overview of recent developments in lentiviral vector technology and their applications for lung disease treatment. Additional data will be presentedregarding animal models of CF lung disease and their potential utility in pre-clinical studies of efficiency and efficacy of gene transfer.Blair Roszell, MSTwo Step Differentiation of Mouse Embryonic Stem Cells to Definitive Endoderm and Lung Epithelial CellsCell-based therapy is a novel and promising treatment option for lung disease, but deriving large quantities of lung epithelial cells from embryonic stem (ES) cells isstill inefficient. In my talk, I will compare growth factor-based and small molecule-based methods for deriving definitive endoderm. After an additional lung inductionstep, activin/wnt and IDE2 treated cells express a similar profile of lung-specific markers. Furthermore, in fetal pulmonary cell co-cultures, activin/wnt treated cells canintegrate into alveolar forming units; whereas IDE2 treated cells express SP-C, but do not integrate into lung-like structures. Finally, ES-derived lung cells were endotracheallyinjected into preterm mice with evidence of AEII distribution within the lung parenchyma. These studies concludes that a recapitulation of development may enhancederivation of an enriched population of lung-like cells for use in cell based-therapy.Peter I. Lelkes, PhDBiomedical Engineering in the LungThe goal of this invited lecture is to present an overview of current tissue engineering and regenerative medicine -based approaches to repair dysfunctional lungs, withfocus on neonatal and adult pulmonary diseases. Specifically, we will present our developmental biology-based studies to create vascularized alveolar structures in vitroand in vivo. In addition, we will discuss attempts by us and others to optimize the directed differentiation of embryonic stem cells towards pulmonary epithelial and otherlung-specific cell types for distal lung tissue engineering and regeneration.John F. Engelhardt, PhDNew Developments in Animal Models of Cystic FibrosisCystic fibrosis (CF) is a recessive disease that affects multiple organs and is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene.Animal modeling of this disease has been challenging, with species- and strain-specific differences in organ biology and CFTR function influencing the emergence of diseasepathology. CF mice have been an invaluable system for dissecting the biology of CFTR function in certain organs, however, they generally lack pancreatic and spontaneouslung disease seen in humans with CF. Recently, CF pig and ferret models have been generated. Comparative analysis of these CF models may help to understand how thepleiotropic functions of CFTR in multiple organs influence disease progression.Special NIH Program Session 21610:30 am to 12:30 pmRoom: Thurgood Marshall WestNIH Resources for Cell and Gene Therapy InvestigatorsModeratorCheryl L. McDonald, MDSpeakersDaniel Rosenblum, MDPThe National Gene Vector Biorepository and Coordinating Center (NGVBCC)The NGVBCC provides an array of support services for NIH-supported investigators engaged in research on Gene Therapy. The services include archiving of biologicalmaterials, insertional site analysis, pharmacology and toxicology resources, and a reagent repository. It has an open database and educational resource. The archiving andanalytical services are limited to investigators at academic and other not for profit institutions. We will review the scope of the services, methods for accessing them, waysof meeting eligibility for their use, website link information, specimen submission and electronic access, and other relevant information pertinent to use of the facility.How the Clinical and Translational Science Awards (CTSA) Program can Support Cell and Gene Therapy InvestigatorsThe CTSA program replaced the GCRC (General Clinical Research Center Program) with a much broader support for novel product and team science within and betweenacademic institutions and other related research support such as the NIH and industrial sponsors. The aim is to streamline project development, review, and implementationof translational and clinical research by providing support from a variety of services such as biostatistics, research design, ethics, clinical research management,informatics, and regulatory knowledge (including FDA). It also facilitates the creation of networks between academic centers and the recruitment of trial participants fromthe community. The presentation will review pertinent summary information about the CTSA program including web access to program information, access to services,potential support from CTSA-related key functions for development of clinical trials, and a brief description of concierge service (a team of experts who can provide supportin the creation and approval of a clinical trial).EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 47Program ScheduleCatherine McKeon, PhDPThe NIDDK Molecular Therapy Centers and Cell Therapy ProgramThis presentation will cover the NIDDK Molecular Therapy Centers and the Cell Therapy Program, as well as some other programs that offer resources to investigators.David G. Badman, PhDThe NIH Rapid Access to Interventional Development Program (NIH-RAID)The NIH Roadmap has established the NIH-RAID Program (Rapid Access to Interventional Development), to make available, on a competitive basis, critical resourcesneeded for development of new small molecule or natural product-derived therapeutic agents. This program, part of the Translational Research component of Reengineeringthe Clinical Research Enterprise, uses resources of the National Cancer Institute’s (NCI) Developmental Therapeutics Program and the National Heart Lung and BloodInstitute’s (NHLBI) Gene Therapy Resource Program. Services provided depend upon the project and strength of the preliminary data. Services potentially available include:bulk supply, GMP manufacturing, formulation, assay development suitable for pharmacokinetic testing, and animal toxicology. Assistance also can be provided in the regulatoryprocess. Currently, animal efficacy studies are not supported; neither are syntheses nor formulation of recombinant proteins or monoclonal antibodies. However, theNIH-RAID Pilot will consider requests for services to support later-stage preclinical development of these entities. Manufacture of certain gene vectors (non-GMP viral andnon-viral gene vectors and GMP-grade adeno-associated virus and lentivirus vectors) can be requested, and preclinical studies of vectors may be supported. Additionally, theNIH-RAID Pilot will now consider requests for manufacture of small molecule or natural product material for any clinical study. Proposals must originate from academic ornon-profit investigators, as well as companies eligible for Small Business Innovation Research Program (SBIR). Collaboration with larger industry partners is encouraged.Roy S. Wu, PhDThe NCI Experimental Therapeutics Program (NExT) and the Chemical Biology Consortium (CBC)The NCI has recently consolidated their drug discovery and development efforts into a single pipeline for increased timeliness and efficiency and with an emphasis onunmet clinical needs. Researchers in academia, government or industry, either nationally or internationally, may apply. NCI is committed to moving high-priority discoveryand development projects through to proof-of-concept clinical trials in a partnership relationship. NExT is not a grant or contract mechanism of support. Rather, projectswill be evaluated and ranked by a peer committee followed by internal committees that will assess clinical need, develop project budgets and milestones with go/no godecisions, and provide access to the NCI’s drug discovery and preclinical and clinical development resources at no cost to the applicant. The resources include activities suchas production of pharmaceutical-grade material, development of clinical formulations, and first-in-human studies. The discovery arm of NExT, known as the NCI ChemicalBiology Consortium or CBC, is a collaborative network of 12 Centers that provide access to high-throughput screens and chemistry to optimize compounds for human use.Applications for potential NExT projects are accepted online four times a year. Visit http://next.cancer.gov/ for application instructions and more information.Danilo A. Tagle, PhDThe NINDS Translational Research ProgramThe NINDS Translational Research Program is specifically focused on pre-clinical therapy development necessary to begin clinical testing of therapeutic candidates forneurological disorders. This program supports the pre-clinical development of drugs, biologics, and devices including activities that lead to Investigational New Drug (IND)or Investigational Device Exemptions (IDE) applications to the Food and Drug Administration (FDA). Supported projects can include lead optimization, pre-clinical efficacytesting, predictive ADMET (absorption, distribution, metabolism, excretion, and toxicology) testing, formulation, manufacture, pharmacology, toxicology, and IND or IDEsubmission. For entry to the program, projects must have one or more identified therapeutic leads and convincing proof-of-principle on efficacy demonstrated in crediblemodels of the disease or against defined disease targets.Thursday, May 20 thLisbeth Welniak, PhDProduction Assistance for Cellular Therapies (PACT)The PACT Group is an NHLBI-funded initiative that is committed to the advancement of effective cell therapies. This program was renewed in January, 2010 for a secondfive-year period of funding. PACT supports the development of novel somatic cell therapy products by providing production assistance to the cell therapy community, aswell as educational training via web seminars and at meetings. Production assistance is provided through the funded contract manufacturing of therapeutic cell products atPACT processing facilities. These facilities offer scale-up capability and expertise in the translational development needed to produce cell therapy products under cGMP andcGTP regulations. PACT’s educational training focuses on three general areas: translational development/scale-up and manufacture of cell therapy products; and qualityassurance and regulatory issues. The objective of the PACT program is to continue to advance cellular therapy research in the areas of regeneration of damaged/diseasedtissues, organs, and biologic systems, and targeted treatments for serious diseases without effective therapies. The cell processing facilities will support translationalresearch in novel cell therapies to advance the field of cellular therapy and to enable scientifically meritorious basic science research to reach the clinical trial stage. Pleasevisit the PACT website at www.pactgroup.net for more information regarding the PACT program.

48American Society of Gene & Cell TherapyProgram ScheduleThursday, May 20 thSonia Skarlatos, PhDThe Center for Fetal Monkey Gene Transfer for Heart, Lung, and Blood DiseasesAnother unique resource that NHLBI offers to gene therapy researchers is the Center for Fetal Monkey Gene Transfer for Heart, Lung, and Blood Diseases at the Universityof California, Davis (http://www.cfmgt.ucdavis.edu/). Established in 2001, this program provides NHLBI-funded investigators with essential expertise, services, andresources to evaluate the safety and efficacy of gene transfer strategies as they emerge.The NHLBI Gene Therapy Resource Program (GTRP)The NHLBI Gene Therapy Resource Program (GTRP) was initiated in March 2007 and since that time it has become a very active and valuable program. The programoffers several services at no cost to investigators researching gene therapy for heart, lung, and blood disorders. The GTRP includes four core labs to assist researchers withpreclinical vector production, pharmacology and toxicology testing, and production of clinical-grade AAV and lentiviral vectors. Additionally, there is a Clinical CoordinatingCenter to assist both investigators and the NHLBI in all aspects of the program.The Science Moving Towards Research Translation and Therapy (SMARTT) ProgramThe purpose of the SMARTT program is to assist translation to the clinic of novel synthetic, natural, or biologic therapeutic interventions arising in the scientific communityfor the treatment of heart, lung, and blood diseases. SMARTT will provide resources in the areas of preclinical and clinical-grade production and testing for biologics, nonbiologicsand small molecules in accordance with Good Manufacturing Practices (GMP), and in the conduct of pharmacology/toxicology studies. In addition, SMARTT willprovide regulatory assistance to investigators wishing to conduct early stage clinical trials.Ying Huang, PhDCommunication with FDA/CBER/OCTGT (Office of Cellular, Tissue and Gene Therapies) Open Microphone Question and Answer PeriodThis talk will introduce the audience to the pathways that are currently available in CBER/OCTGT to facilitate communication between CBER and the sponsor of an investigationalcellular or gene therapy product to enable the conduct of safe clinical trials. This talk will briefly touch upon the various disciplines involved in the developmentprogram of these novel products, with a focus towards supporting translation from bench to bedside.Open Microphone Question and Answer PeriodLunch Break12:30 pm – 2:00 pmMeet-the-Investigator Lunch 22012:30 pm - 1:45 pmRoom: HardingMusculo-SkeletalSpeakersJeffrey Chamberlain, PhD & Paula Clemens, MDMeet-the-Investigator Lunch 22112:30 pm - 1:45 pmRoom: HooverCancer Stem CellsSpeakersTimothy P. Cripe, MD, PhD & Samuel D. Rabkin, PhDEXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 49Program ScheduleOral Abstract Session 2302:00 pm - 4:00 pmRoom: Marriott Ballroom Salons 2 & 3AAV Vectors: Vector TraffickingCo-ChairsDavid V. Schaffer, PhD & Xiao Xiao, PhD(Abstracts 1-8; see page 86)Oral Abstract Session 2312:00 pm - 4:00 pmRoom: Maryland SuiteDNA Vectorology & Gene TargetingCo-ChairsPerry B. Hackett, PhD & Matthew H. Porteus, MD, PhD(Abstracts 9-16; see page 86)Oral Abstract Session 2322:00 pm - 4:00 pmRoom: Wilson ABCNeurologic & Ophthalmic Gene & Cell TherapyCo-ChairsMichael Kaplitt, MD, PhD & Deborah J. Watson, PhD(Abstracts 17-24; see page 87)Thursday, May 20 thOral Abstract Session 2332:00 pm - 4:00 pmRoom: Thurgood Marshall WCancer – Immunotherapy T Cell StudiesCo-ChairsChiara Bonini, MD & Dean A. Lee, MD, PhD(Abstracts 25-32; see pages 87-88)Oral Abstract Session 2342:00 pm - 4:00 pmRoom: Marriott Ballroom Salon 1Cancer-Oncolytic Viruses ICo-ChairsWinald Gerritsen, MD PhD & David H. Kirn, MD(Abstracts 33-40; see page 88)

50American Society of Gene & Cell TherapyProgram ScheduleOral Abstract Session 2352:00 pm - 4:00 pmRoom: Virginia SuiteImmunologic & Host Responses in Gene & Cell TherapyCo-ChairsEvanthia Galanis, MD, DSc & Maciej S. Lesniak, MD, FACS(Abstracts 41-48; see pages 88-89)Thursday, May 20 thOral Abstract Session 2362:00 pm - 4:00 pmRoom: Delaware SuiteOligonucleotide & RNAi Therapeutics ICo-ChairsDieter C. Gruenert, PhD & Faye A. Rogers, PhD(Abstracts 49-56; see page 89)Outstanding New Investigator Symposium 2404:30 pm - 6:15 pmRoom: Marriott Ballroom Salons 1, 2 & 3Outstanding New Investigator SymposiumChairJohn J. Rossi, PhDSpeakersAlessandra Biffi, MDRendering Hematopoietic Stem Cell Transplantation Efficacious for the Treatment of Lysosomal DisordersTransplantation of hematopoietic stem cells (HSC) from healthy donors has been employed in Lysosomal Storage Disorders (LSD) for delivering a functional hydrolaseto the affected tissues. However, likely due to the slow kinetics of infiltration of the nervous system, the efficacy of the transplant is poor in LSD with severe neurologicmanifestations. The limited efficacy of the allogeneic procedure may be implemented by: i) understanding the mechanisms of myeloid infiltration into affectedtissues, and in particular into the brain, in order to favour and accelerate this phenomenon; ii) rendering the transplanted HSC and or their progeny more effectivethan normal donors’ cells in enzyme delivery by means of gene transfer to enhance the metabolic correction of the affected tissue. We have addressed these issuesattempting to develop an effective and safe therapeutic approach for different LSD with CNS involvement, for one of which we recently started clinical testing.EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 51Program ScheduleKevin V. Morris, PhDUtilizing the Endogenous Long Non-Coding RNA Pathway in Human Cells to Transcriptionally Modulate Gene ExpressionObservations over the last few years have demonstrated that non-coding RNAs can transcriptionally modulate gene expression in human cells. Recent data hasinferred long non-coding RNAs as endogenous effector molecules regulating gene transcription in human cells. Importantly, this non-coding RNA based mechanism canbe taken advantage of to either transcriptionally silence gene expression in a specific long-term manner or activate gene transcription by the targeted degradation ofgene specific regulatory long antisense non-coding RNAs.Thursday, May 20 thBakhos A. Tannous, PhDEx-Vivo Monitoring of In Vivo Gene and Cell TherapySecreted reporters are useful tools for the detection and non-invasive monitoring of different biological processes in experimental models. We have characterized thenaturally secreted Gaussia luciferase (Gluc) as a highly sensitive reporter for quantitative assessment of cells in vivo by measuring its activity in few microliters ofblood. The Gluc blood level is linear with respect to cell number and therefore is a sensitive tool for monitoring tumor growth and response to therapy, gene transfer,viral infection and replication, transcription factor activation, as well as circulating cells survival and proliferation. We also applied the Gluc assay to monitor the effectof novel gene therapy based on the constitutively active mutant human brain sodium channel as well as tumor-specific nuclear factor kappa B inducible system drivingthe expression of a suicidal gene. The Gluc blood assay complements in vivo bioluminescence imaging which has the ability to localize the signal and provides amultifaceted assessment of biological processes in experimental disease and therapy models.Charles P. Venditti, MD, PhDGene Therapy for Methylmalonic Acidemia (MMA)The hereditary methylmalonic acidemias are inborn errors of metabolism and are excellent candidates for gene and cell therapy. We have generated new insights frommouse models and patient investigations to instruct successful pre-clinical experiments. To facilitate the implementation of clinical gene therapy for MMA, we havedeveloped and validated a sensitive isotope ratio mass spectrometry technique to non-invasively monitor whole-body metabolic effects after gene delivery.

52American Society of Gene & Cell TherapyProgram ScheduleExhibit Hall Open & Networking Reception6:15 pm – 8:15 pmRoom: Exhibit Hall CThursday, May 20 thPoster Session I6:15 pm – 8:15 pmRoom: Exhibit Hall B South, CAAV Vectors I(Abstracts 57 through 72; see pages 89-90)Adenovirus and Other DNA Virus Vectors I(Abstracts 73 through 86; see pages 90-91)Targeting Gene Modification and Integration(Abstracts 87 through 99; see pages 91-92)Physical Methods of Delivery(Abstracts 100 through 116; see page 92)Chemical and Molecular Conjugates I(Abstracts 117 through 132; see page 93)Genetic and Metabolic Diseases Gene & Cell Therapy I(Abstracts 133 through 147; see pages 93-94)Musculo-skeletal Gene & Cell Therapy I(Abstracts 148 through 160; see pages 94-95)Infectious Diseases and Vaccines: Vaccine Related Gene Transfer Research(Abstracts 161 through 174; see pages 95-96)Cancer – Immunotherapy I(Abstracts 175 through 190; see pages 96-97)Cancer-Oncolytic Viruses I(Abstracts 192 through 204; Abstract 191 moved to Oral Session 413; see pages 97-98)Cancer-Targeted Gene & Cell Therapy I(Abstracts 205 through 219; see pages 98-99)Hematologic and Immunologic Gene & Cell Therapy I(Abstracts 220 through 233 and Abstract 869 which has been moved from Poster Session III; see page 99)Gene Regulation(Abstracts 234 through 244; see page 100)Oligonucleotide & RNAi Therapeutics I(Abstracts 245 through 259; see pages 100-101)Stem Cell Biology(Abstracts 260 through 273; see pages 101-102)Cell Processing and Vector Production I(Abstracts 274 through 282; see pages 102)Late Breaking Science I(Abstracts 922 through 932; Abstract 926 withdrawn; see pages 102-103)EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 53Program ScheduleFoundation Symposium 2507:00 pm - 10:00 pmRoom: Thurgood Marshall WestExpanding Frontiers in Spinal Muscular Atrophy Gene TherapyChairChristian L. Lorson, PhDSpeakersChristian L. Lorson, PhDIntroduction: Perspectives on SMA TherapeuticsC. Frank Bennett, PhDRNA Targeting Therapeutics for the Treatment of Motor Neuron DiseasesMarco Passini, PhDGene and Antisense Therapies in SMA MiceBrian K. Kaspar, PhDRescue of a Spinal Muscular Atrophy Mouse Model by Early Postnatal Delivery of SMN with scAAV9 and Clinical Development PlansPetra Kaufman, MDSMA Clinical Trials – NINDS PerspectiveThursday, May 20 thFoundation Symposium 250 is supported by the following ASGCT partners:

54American Society of Gene & Cell TherapyProgram ScheduleFriday, May 21Friday, May 21 stPlenary Abstract Session 3008:00 am - 10:00 amRoom: Marriott Ballroom Salons 1, 2 & 3Top Oral Abstracts Plenary SessionCo-ChairsStanton L. Gerson, MD & John J. Rossi, PhDSpeakersMervin C. Yoder, MD IntroducesEirini P. Papapetrou, MD, PhDTherapeutic Transgene Expression in Patient-Specific iPS Cells after Selection of “Safe Harbors” for Lentiviral Vector IntegrationJames Ellis, PhD IntroducesAxel Schambach, MD PhDA Novel Lentiviral Expression System Reveals Patchwork Colony Formation during Reprogramming to Induced Pluripotent Stem CellsDieter C. Gruenert, PhD IntroducesErica B. Schleifman, BSTargeted Genomic Modification and Inactivation of the CCR5 Gene Using PNA-Induced Homologous RecombinationMatthew H. Porteus, MD, PhD IntroducesRichard Gabriel, Dipl.-Biol.Lentiviral Microarrays for High-Throughput and Real-Time Monitoring of Gene Expression DynamicsBruce Sullenger, PhD IntroducesJiehua Zhou, PhDSystemic Administration of Sendrimer- and Aptamer-siRNA Conjugates Efficiently Suppresses HIV-1 InfectionChiara Bonini, MD IntroducesAntonio Di Stasi, MDCASPALLO: Phase I Clinical Trial of Allodepleted T Cells Transduced with Inducible Caspase 9 Suicide Gene after Haploidentical Stem Cell TransplantationBreak10:00 am – 10:30 amScientific Symposium 31010:30 am - 12:30 pmRoom: Virginia SuitePersonalized Cell and Gene TherapyChairJohn J. Nemunaitis, MDSpeakersJohn J. Nemunaitis, MDSuccess of Gene Therapy - A Personalized and Personal ApproachClinical use of molecular science is coming of age! Numerous targeted therapies, many related to gene based technology, in particular involving RNA interference platforms,are undergoing clinical track development. Mechanisms for cancer specific plasmid delivery are unfolding in the clinical arena. Furthermore, gene based vaccinesare showing improved promise. These dynamics combined with more efficient and economic quantitative proteogenomic technology development will enable a personalizedapproach to cancer therapy. Results of personalized gene and cell based therapies will be discussed.EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 55Program ScheduleLilia Bi, PhDRecovery and Reduction Costs for Cell-based Gene Therapy ProductsThis presentation will discuss the recovery and reduction costs for cell-based gene therapy products from following aspects:What is the purpose of cost recovery and where does it apply?Cost recovery regulations and rulesWhat can be charged for under cost recovery?Process for requesting cost recovery and what information sponsors need to providePotential cost reduction by following the step-wise approach to implementing cGMP’s and product characterizationCarl H. June, MDGenetically Engineered T Cells: Can We Afford Not To Do This?A key concern with adoptive cell transfer therapy is a financial issue related to the potential costs of a lymphocyte infusions. Factors that relate to the eventual pricing ofa personalized therapy consisting of autologous T cells are numerous and include issues such as the magnitude of efficacy, durability of responses, safety and tolerability.In this regard, it is instructive to consider allogeneic stem cell transplantation procedures that have potent efficacy and considerable toxicity, and whether adoptive T celltransfer therapy could supplant and extend this procedure.Jeffrey Schlom, PhDRecombinant Cancer Vaccines as Monotherapy and in Combination TherapyRecombinant poxviral vaccines have been developed that contain the transgenes for one or more tumor associated antigens and three T-cell costimulation molecules(TRICOM). Preclinical studies have shown that these vaccines have the ability to break tolerance and induce therapeutic activity in several models. Randomized clinicaltrials in patients with prostate cancer have shown statistical improvements in survival. Preclinical studies have shown that radiation and or chemotherapy can alter the phenotypeof tumor cells and render them more susceptible to T-cell lysis; combination therapy studies with vaccine are ongoing. Recently results have shown that moleculesinvolved in the Epithelial to Mesenchymal Transition (EMT) metastatic process can be targeted by vaccine therapy.Scientific Symposium 31110:30 am - 12:30 pmRoom: Marriott Ballroom Salon 1Stem Cells and MalignancyChairEvan Y. Snyder, MD, PhD, FAAPSpeakersInder M. Verma, PhDCancer Stem Cells: Lessons from GlioblastomasWe have generated novel mouse models of human gliomas using lentiviral vectors containing oncogenes or shRNA to suppressor genes. The resulting tumors had stemcell properties. We will discuss the implications of these results.Roger J. Packer, MDChildhood Brain Tumors: Opportunities for Biologic-Based TherapiesBrain tumors are the most common solid malignancy of childhood and are the leading cancer related cause of morbidity and mortality in the pediatric-aged patients.Progress has been made in the management of childhood brain tumors, but lack a clear understanding of the molecular pathogenesis of these tumors and ways to exploitthis molecular pathogenesis for treatment has slowed progress. Over the past decade, there have been tremendous advances in the understanding of the molecularunderpinnings of a variety of different childhood brain tumors including the most common malignant brain tumor, the medulloblastoma, and the most common benigntumor, the low grade-glioma. Molecular targets have been identified and a host of biologic agents including antiangiogenesis drugs, tyrosine kinase growth inhibitors, andagents interfering with intracellular signaling are in clinical trials. To date, their use has not been associated with improvements in survival but there is great enthusiasm incontinuing their study with the hope of developing more effective and safer therapies.Friday, May 21 st

56American Society of Gene & Cell TherapyProgram ScheduleEvan Y. Snyder, MD, PhD, FAAP“Lineage Mapping” The Development of a Brain TumorCarl Bart Rountree, MDThe Role of Stem Cells and Cancer Stem Cells in Liver CancerHepatocellular carcinoma (HCC) ranks as the third most frequent cause of cancer-related mortality in the world; and over the last four decades, traditional cytotoxicchemotherapy has failed to improve patient survival in HCC. Typically, patients develop HCC after many years of chronic liver injury, during which time, there is a significantexpansion of the liver stem cell pool. Increasing evidence indicates that liver cancer stem cells (CSC) are the origin of a subset of HCC, and patients with a CSC phenotypeHCC have a significantly worse prognosis. Additionally, using stem cell surface markers such as CD133, purified liver CSC populations have been identified within humanHCC cell lines and mouse models that mimic human chronic liver injury and HCC development. These liver CSCs are resistant to traditional chemotherapy agents andligand-receptor mediated apoptosis, form tumors at very limited dilution, and represent a critical therapeutic target in future HCC treatments.Friday, May 21 stScientific Symposium 31210:30 am - 12:30 pmRoom: Thurgood Marshall WestCurrent Status of Genetic VaccinesChairStephen Gottschalk, MDSpeakersSi-Yi Chen, MD, PhDDC-based Tumor Vaccine by Combining SOCS1 Silencing and TLR SignalingMichael A. Barry, PhDGene-based Vaccines Against Mucosal PathogensThe vast majority of pathogens enter the body at mucosal surface. Yet, most vaccine strategies are delivered into the systemic immune system where induced immunologicalmemory may not efficiently “cross-over” to mucosal surfaces to provide barrier protection against these pathogens. To maximize protection, we will discuss comparisonsof replication-competent and replication-defective first generation and helper-dependent adenoviral vaccines for their utility in systemic and mucosal infections by SHIV,influenza, and methicillin-resistant Staphylococcus Aureus (MRSA). We will also discuss “stealth” strategies during vaccination to evade pre-existing and vector-inducedimmunity against adenovirus including serotype-switching and PEGylation.Sattva S. Neelapu, MDTargeting Chemokine Receptors with Fusion DNA VaccinesTherapeutic vaccination with patient-specific tumor-derived idiotype protein conjugated to a carrier molecule, keyhole limpet hemocyanin and administered with granulocyte-monocytecolony-stimulating factor as an adjuvant was shown to induce tumor-specific immune responses and molecular remissions in follicular lymphoma patientsin phase II clinical trials. Results from a recently completed randomized controlled double-blind phase III trial suggested that administration of idiotype protein vaccine inthe setting of minimal residual disease improves disease-free survival in patients with follicular lymphoma as compared with control. However, a major limitation of thisstrategy is the requirement to generate a custom-made protein vaccine for each patient, by a process that is expensive, laborious, and time-consuming. DNA vaccines maybe produced more rapidly and provide an alternative to protein vaccines. Strategies to enhance the efficacy of DNA vaccines by fusing tumor antigens to chemokines andusing novel adjuvants will be discussed.Stephen Gottschalk, MDAdenoviral Vaccines for Enhancing T-cell Therapies for CancerAlthough the benefits of T-cell therapy for cancer can be increased by prior lymphodpeletion of the host, this process has usually required chemotherapy or radiation.Vaccination with tumor associated antigens to which the transferred T cells respond should be a less toxic means of promoting antitumor activity, but to date this hasproved ineffective, favoring instead the transition to a non-cytotoxic immune response. We have developed a new adenoviral based vaccine that contains antigen, atoll-like receptor 5 activator and an inhibitor of the antigen presenting attenuator A20. Administration of this vaccine prior to T-cell transfer induces a strong Th1-polarizingenvironment leading to potent antitumor effects even in the absence of lymphodepletion and even when vaccination or T-cell transfer alone are ineffectual. Such Th1-polarizing vaccines may be of value when enhancement and maintenance of a Th1 response is desirable.EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 57Program ScheduleScientific Symposium 31310:30 am - 12:30 pmRoom: Maryland SuitePrecise Genetic and Post-transcriptional Modification of Stem CellsChairDieter C. Gruenert, PhDSpeakersPeter M. Glazer, MD, PhDTargeted Gene Modification in Hematopoietic Stem Cells via Triple Helix FormationTriple helix-forming peptide nucleic acids (PNAs) can bind to polypurine regions in DNA in a sequence-specific manner. The resulting triplexes constitute an altered DNAstructure that can stimulate DNA repair and recombination in a site-specific manner in human cells. We have found that transfection of human hematopoietic stem cellswith triplex-forming PNAs plus short single-stranded donor DNAs can produce targeted modification of disease related genes. Site-directed modification of two key humangenes has been achieved: (1) the human beta-globin gene, mutations in which cause thalassemia and sickle cell anemia; and (2) the CCR5 gene, which encodes aco-receptor for HIV-1 entry into human cells. Triplex-modified hematopoietic stem cells have been transplanted into immune deficient mice, with full engraftment, normalpatterns of differentiation, and persistence of the targeted gene modification for up to four months.Linzhao Cheng, PhDGene Targeting in Human Pluripotent Stem CellsHuman induced pluripotent stem (iPS) cells reprogrammed from adult somatic cells resemble embryonic stem (ES) cells that can proliferate indefinitely in culture whilemaintain their full differentiation potential (pluripotency), therefore providing an unlimited resource for disease research and therapy. These self-renewable stem cells alsomake it feasible to achieve gene targeting (to correct or create DNA mutation) in the genome of normal human cells by homologous recombination (HR) that is naturalbut inefficient process for genome repair. To enhance HR-mediated gene targeting efficiency we also incorporate the strategy utilizing zinc finger nuclease (ZFN), whichis designed as a fusion protein with multiple zinc-finger DNA binding and the FokI endonuclease domains. Upon dimer formation, two ZFNs (co-delivered with a donorDNA template) can create a sequence-specific DNA double strand break to stimulate HR near the cut site. We found that ZFNs enhanced HR by >100-1,000 fold in eithercreating or correcting a mutation in human iPS and ES cells.Dieter C. Gruenert, PhDModification of the CF and Sickle Cell Anemia iPS cells by SFHRInduced pluripotent stem (iPS) cells have the potential of significantly advancing the development of stem cell-based therapies, especially as they pertain to inheriteddiseases. The potential to generate autologous pluripotent stem cells to repair and regenerate tissues and organs damaged by disease pathologies is a cornerstone ofpatient-specific therapy. Cystic fibrosis (CF), the most common inherited disease in the Caucasian population, and sickle cell anemia (SCA), the most prevalent hemoglobinopathycommonly found in individuals of African, Middle Eastern, Mediterranean, and Southeast Asian decent, have significant multiorgan damage that will benefit fromcellular repair. In this context, somatic cells from a CF patient with a ∆F508/∆F508 genotype and a SCA patient have been reprogrammed, characterized, and correctedby small fragment homologous replacement (SFHR).Robert Blelloch, MD, PhDMicroRNA Regulation of Embryonic Stem Cell Self-Renewal and DifferentiationFriday, May 21 st

58American Society of Gene & Cell TherapyProgram ScheduleFriday, May 21 stScientific Symposium 31410:30 am - 12:30 pmRoom: Delaware SuiteNew Physical Gene Delivery System and VectorologyChairShulin Li, PhDSpeakersChristian Plank, PhDNanomagnetic Nucleic Acid DeliveryPhysical force has been used with great success to enable, enhance or localize nucleic acid delivery. In magnetofection, which is one such method, vectors for nucleic aciddelivery are associated with magnetic nanoparticles to accumulate or retain them at target sites with gradient magnetic fields. This concept of magnetic drug targetingenhances the efficiency of the delivery process over several orders of magnitude. This we have exploited to generate an integrated method of magnetic cell separation andgenetic modification, to boost the efficacy of oncolytic adenovirus and for establishing a tumor vaccine to treat feline fibrosarcoma. In other recent approaches we focus onextending the concept of magnetofection with thermo-sensitive magnetic liposomes, magnetic microbubbles and magnetic aerosols for magnetically guided drug delivery.Declan M. Soden, PhDEndoscopic Electroporation: Targeted Gene Delivery to Intraluminal TissuesThe minimally invasive control of primary tumours is a critically important part in the treatment process as it relieves symptoms, forestalls complications, facilitates responsivenessto systemic therapies and is often curative. We have developed a device, which allows for an endoscopic cancer treatment, specifically targeting colorectal, gastricand oesophageal cancers by applying a brief electric pulse to the tumour. This greatly enhances tissue permeability maximizing the local/tumor absorption of therapeuticagents (drugs or DNA). Absorption occurs only in the area that has been treated with the electrical field and therefore is targeted to the tumor, leaving surrounding healthytissues unaffected. Our research has examined the efficacy of the device for targeted gene delivery to intraluminal tissues in large animals. We have compared the transfectionefficacy of a standard CMV driven reporter gene (b-galactosidase) in both murine and porcine tissues. In addition we have examined the efficacy of a DNA vectorcoding for a viral RNA polymerase encoded from the Semliki Forest Virus in comparison to the CMV driven vector.The treatment of spontaneous canine colorectal cancers has also been conducted using the device to facilitate local drug (bleomycin) absorption after tumor tissueelectroporation. The results have demonstrated the treatment to be effective and safe with complete tumor ablation noted in the two inoperable cases treated to date.All procedures were conducted as a simple colonoscopy type procedure with no adverse side effects recorded. A phase I clinical study with the device is due to commenceearly 2010 to treat patients with inoperable rectal cancer and electrochemotherapy.Kate E. Broderick, PhDDermal Electroporation Devices for Prophylactic DNA Vaccine DeliveryDuring the presentation, Dr. Broderick will discuss novel prototype dermal devices developed by Inovio and the pre-clinical Immunogenicity data generated from thesedevices in a number of animal models.Laurence JN Cooper, MD, PhDNon-viral Gene Transfer into Human T CellsNon-viral approaches can be used to genetically modify T cells for therapy. We have combined electroporation with the Sleeping Beauty (SB) transposase/transposon DNAplasmid system to introduce desired transgenes. By improving the efficiency of electroporation with designer devices and improving the efficiency of integration by adaptingthe SB system for human translation, we seek to implement physical gene transfer systems for clinical trials.EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 59Program ScheduleScientific Symposium 31510:30 am - 12:30 pmRoom: Marriott Ballroom Salons 2 & 3Genetic Modification of Stem Cells for Therapeutic ApplicationsChairFrederic D. Bushman, PhDSpeakersChristof von Kalle, MD PhDThe Clonal Distribution of Insertion Site RepertoiresRetroviral vectors have been successfully used for the correction of inherited immune diseases in clinical trials. However, qualitative and quantitative in vivo monitoring ofgene modified hematopoiesis in several clinical gene therapy trials revealed that vector induced side effects, ranging from subtle and not clinically obvious effects to clonaldominance and, rarely, leukemogenesis, have to be considered.Clonality data on oncoretroviral and lentiviral clinical gene therapy trials (i.e. CGD, SCID, WAS, ALD) show that integration site distribution is non-random and mayinfluence cellular gene expression, thus inducing changes in the clonality of the hematopoietic repopulation. Incorporation of next generation sequencing technologiessubstantially improve in depth analyses and monitoring of individual and global clonal contribution in a hitherto unexpected resolution. Prospective monitoring of vectorintegration sites in clinical gene therapy studies is feasible, can detect side effects of gene therapy at the clonal level, and may help to gain new insights into the basicmechanisms leading to specific clonal behaviour in vivo. Genome wide insertion studies will allow to improve the safety and performance of viral and non-viral integratingvector systems.Matthew H. Porteus, MD, PhDGene Targeting with Zinc Finger Nucleases in Primary CellsGene targeting by homologous recombination has the potential to be both a safer and more efficacious approach to gene therapy. Therapeutically relevant rates of genetargeting have been achieved by using zinc finger nucleases in a variety of tissue culture cell lines and some primary human cells. We now demonstrate that therapeuticallyrelevant frequencies of gene targeting by homologous recombination can be achieved in primary cells and that these modified cells can be successfully transplantedback into a recipient. The demonstration that primary cells can be isolated, precisely modified ex vivo and then transplanted back into a recipient mimics the strategy weare working towards in humans as a cure for patients with monogenic diseases.Frederic D. Bushman, PhDHIV DNA Integration: Mechanism and ConsequencesThe lecture will cover integration by HIV and HIV-based vectors. Recent results from gene therapy trials will be presented. The lecture will also cover development ofimproved new methods for integration site isolation and analysis.Ko Mitani, PhDChromosomal Manipulation of Human Pluripotent Stem Cells using Adenoviral VectorsIn order to fully utilize human induced pluripotent stem (iPS) cells and embryonic stem (ES) cells for basic research and clinical applications, it is essential to developefficient methods for homologous recombination (HR) in these cells. We have shown that, by delivering gene-targeting cassettes using helper-dependent adenoviralvectors (HDAdVs) into human ES/iPS cells, gene knock-in/-out has been efficiently achieved at both transcriptionally active and inactive loci. On average, one out of2 - 20 x 105 infected cells was homologous recombinant. The efficiencies of HR per chromosomal integration were 10 - 50% (30 - 90% with negative selection), whichwere ~100-fold higher than those obtained by other DNA delivery methods. These findings suggest that HDAdV-mediated HR is not only a highly efficient strategy forchromosomal manipulation of pluripotent stem cells but also a viable option for ex vivo gene repair therapy using iPS cells derived from patients of inherited diseases,which would overcome the risk of insertional mutagenesis.Friday, May 21 stLunch Break12:30 pm – 2:00 pm

60American Society of Gene & Cell TherapyProgram ScheduleOral Abstract Session 3202:00 pm - 4:00 pmRoom: Marriott Ballroom Salons 2 & 3Clinical Gene & Cell TherapyCo-ChairsGuangping Gao, PhD & Matthew H. Porteus, MD, PhD(Abstracts 289-296; see pages 104-105)Oral Abstract Session 3212:00 pm - 4:00 pmRoom: Virginia SuiteRNA Virus VectorsCo-ChairsFabio Candotti, MD & Robert G. Hawley, PhD(Abstracts 297-304; see page 105)Oral Abstract Session 3222:00 pm - 4:00 pmRoom: Marriott Ballroom Salon 1AAV Vectors: Vector BiologyCo-ChairsDouglas M. McCarty, PhD & Matthew D. Weitzman, PhD(Abstracts 305-312; see pages 105-106)Friday, May 21 stOral Abstract Session 3232:00 pm - 4:00 pmRoom: Delaware SuiteGene Therapy for Lysosomal Storage Diseases and Other Genetic DisordersCo-ChairsCary Harding, MD & Chester B. Whitley, PhD MD(Abstracts 313-320; see page 106)Oral Abstract Session 3242:00 pm - 4:00 pmRoom: Wilson ABCPhysical Methods of DeliveryCo-ChairsJeffrey Hughes, PharmD, PhD & Nancy Smyth Templeton, PhD(Abstracts 321-328; see pages 106-107)EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 61Program ScheduleOral Abstract Session 3252:00 pm - 4:00 pmRoom: Thurgood Marshall WCancer-Targeted Gene & Cell TherapyCo-ChairsFrank Marini, PhD & Richard G. Vile, PhD(Abstracts 329-336; see page 107)Oral Abstract Session 3262:00 pm - 4:00 pmRoom: Maryland SuiteHematologic/Immunologic: BasicCo-ChairsDavid Klatzmann, MD, PhD & John F. Tisdale, MD(Abstracts 337-344; see pages 107-108)Break4:00 pm – 4:30 pmFriday, May 21 st

62American Society of Gene & Cell TherapyProgram SchedulePresidential Symposium 3304:30 pm - 6:30 pmRoom: Marriott Ballroom Salons 1, 2 & 3Presidential SymposiumChairKenneth Cornetta, MDSpeakersFriday, May 21 stJohn J. Rossi, PhD Introduces Katherine A. High, MDKatherine A. High, MDOutstanding Achievement Award LectureEXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 63Program SchedulePresidential Symposium 330 — continuedJean Bennett, MD, PhDAn Aye for Gene Therapy: Lessons from a Clinical Trial for Congenital BlindnessGene therapy has the potential to reverse disease or prevent further deterioration of vision in patients with incurable inherited retinal degeneration. The recent demonstrationof safe and stable recovery of retinal/visual function in 12 children and adults with Leber’s congenital amaurosis (LCA) due to RPE65 mutations in a trialbeing carried out at The Children’s Hospital of Philadelphia (CHOP), and encouraging results from two other clinical trials for LCA-RPE65 provide great hope for peoplewith other more common blinding diseases. This presentation will describe the latest safety and efficacy results in the LCA-RPE65 clinical trial being held at CHOP. Thisstudy is now >2.5 years past initiation. In addition, it will describe some of the challenges presented by the nature of the targeted disease itself, hurdles that havebeen navigated in order to conduct the study, and issues of importance for eventual approval of gene augmentation as a therapy for LCA and other blinding diseases.*This presentation involves contributions from the following additional individuals (listed alphabetically): Carmen Acerra, Defne Amado, Alberto Auricchio, SandroBanfi, Jeannette Bennicelli, Erin Bote, Yifeng Chen, Daniel Chung, Ann Fulton, Jeffrey Golden, Rebecca Grant, Bernd Hauck, Daniel Hui, Katherine A. High, BartLeRoy, Arkady Lyubarsky, Albert M. Maguire, Maureen G. Maguire, Kathleen Marshall, Federico Mingozzi, Jessica Morgan, Kristina Narfstrom, Stephen Orlin, EricA. Pierce, Settimio Rossi, Kenneth S. Shindler, Francesca Simonelli, Enrico M. Surace, Edwin Stone, Junwei Sun, Nasreen Syed, Francesco Testa, Nicholas J. Volpe,Jennifer Wellman, J. Fraser Wright, Gui-shuang Ying, Olga Zelenaia, Xiaosong (Sonia) ZhuFriday, May 21 stDavid A. Williams, MDNew Approaches to Gene Therapy for Fanconi AnemiaFA is a rare recessive syndrome characterized by bone marrow failure, congenital anomalies and a predisposition to malignancy. FA cells have a defect in DNA repairthat leads to increased spontaneous chromosomal breakage. Transgenic expression of FA genes in vitro corrects the increased chromosomal breakage and othercellular phenotypes of the disease. In a recent gene therapy trial, we have demonstrated that gene transfer per se is no longer a limitation to the effectiveness ofgene therapy in this disease. Rather our clinical studies show that even early in the disease process there are significant deficiencies in the number and/or functionof hematopoietic stem cells (HSCs) that can be collected and utilized as targets in gene transfer. One approach that could address this deficiency is the derivationof HSC from induced pluripotent stem (iPS) cells reprogrammed from non-blood somatic tissues. Important advantages of iPS cells for application of gene therapyare the apparent unlimited proliferative capacity of such cells (allowing production of large numbers of derived HSC) and the ability to clone such cells allowing bothsingle cell correction of genetic mutations and prospective molecular characterization of manipulated cells prior to therapeutic applications.

64American Society of Gene & Cell TherapyProgram ScheduleExhibit Hall Open & Networking Reception6:30 pm – 8:30 pmRoom: Exhibit Hall CFriday, May 21 stPoster Session II6:30 pm – 8:30 pmRoom: Exhibit Hall B South, CRNA Virus Vectors I(Abstracts 345 through 361; see pages 108-109)AAV Vectors II(Abstracts 362 through 377; see pages 109-110)Adenovirus and Other DNA Virus Vectors II(Abstracts 378 through 391; see page 110)Chemical and Molecular Conjugates II(Abstracts 392 through 407; see pages 110-111)Genetic and Metabolic Diseases Gene & Cell Therapy II(Abstracts 408 through 422 and Abstract 764 which has been moved from Poster Session III; see pages 111-112)Cardiovascular Gene & Cell Therapy(Abstracts 423 through 440; see pages 112-113)Ophthalmic Disorders and Technological Advances(Abstracts 441 through 453; see pages 113-114)Musculo-skeletal Gene & Cell Therapy II(Abstracts 454 through 468; see pages 114-115)Cancer – Immunotherapy II(Abstracts 469 through 487; see pages 115-116)Cancer-Oncolytic Viruses II(Abstracts 488 through 506; see pages 116-117)Cancer-Targeted Gene & Cell Therapy II(Abstracts 507 through 520; Abstract 519 withdrawn; see page 117)Hematologic and Immunologic Gene & Cell Therapy II(Abstracts 521 through 534; see page 118)Immunologic & Host Responses in Gene & Cell Therapy(Abstracts 535 through 554; Abstract 541 withdrawn; see pages 118-119)Oligonucleotide & RNAi Therapeutics II(Abstracts 555 through 569; see pages 119-120)Cell Processing and Vector Production II(Abstracts 570 through 579; see pages 120-121)Late Breaking Science II(Abstracts 933 through 937; see page 121)EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 65Program ScheduleFoundation Symposium 3407:00 pm - 10:00 pmRoom: Marriott Ballroom Salons 2 & 3Progress and Prospects for Gene Therapy for CGD and other Primary ImmunodeficienciesSpeakersMary C. Dinauer, MD, PhDGene Therapy for CGD - From Basic Discoveries to the Start of Clinical TrialsAlessandro Aiuti, MD, PhDConditioning Regimens for Haematopoietic Gene TherapyHarry L. Malech, MDUpdate on Gene Therapy Trials for CGDManuel Grez, PhDThe European Experience on GT for CGDAdrian J. Thrasher, MD, PhDUpdate on Clinical Trials for XC1-SCID, ADA and ALDFoundation Symposium 340 is supported by the following ASGCT partner:Friday, May 21 st

66American Society of Gene & Cell TherapyProgram ScheduleSaturday, May 22ASGCT Business Meeting8:00 am - 8:30 amRoom: Delaware SuiteA light continental breakfast will be served at 7:45 am.Scientific Symposium 4008:30 am - 10:30 amRoom: Maryland SuiteLate Stage Industry Clinical TrialsCo-ChairsDouglas J. Jolly, PhD & Thomas TillettSpeakersWilliam W. Li, MDGene Transfer of FGF1 for Critical Limb Ischemia: A Phase III Clinical TrialRobert Sims, MDProgress in the Development of Sipuleucel-T for the Treatment of Men with Metastatic, Castrate Resistant Prostate CancerSipuleucel-T is an autologous cellular immunotherapy designed to elicit an antitumor response against prostate cancer. Sipuleucel-T is manufactured by incubating antigenpresenting cell precursors with a fusion protein composed of prostatic acid phosphatase linked to GM-CSF. Sipuleucel-T is then reinfused into the patient and the process isrepeated every 2 weeks for a total of 3 infusions. It has been evaluated in 3 randomized placebo-controlled Phase 3 studies in men with metastatic castrate-resistant prostatecancer, which have demonstrated clear evidence of prolongation of survival. The presentation will include an update on the regulatory status of sipuleucel-T currentclinical trials, as well as planned future trials.Ryuichi Morishita, MD, PhDDevelopment of HGF Gene Therapy Drug (Collategen)As HGF is a most potent mitogen to stimulate angiogenesis, a multi-center randomized, placebo-controlled, double blind study for critical limb ischemia (CLI) using HGFplasmid DNA was conducted, based on phase I/IIa open label study at Osaka University. Improvement rate was 70.4 % in HGF and 30.8% in placebo in Fontaine III/Rutherford 4 patients (P=0.014). HGF gene therapy achieved a significantly higher improvement rate of ischemic ulcers compared with placebo (100% vs. 40%,P=0.018). No major safety problems were observed. Based on phase III data, NDA was submitted to Japan Regulatory Agency (MHWL) on 2008. In USA, phase IIIstudy using HGF gene therapy will be started in 2010, since phase III USA study obtained SPA from FDA.Sander van Deventer, MD, PhDGlybera for Lipoprotein Lipase DeficiencySaturday, May 22 ndEXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 67Program ScheduleScientific Symposium 4018:30 am - 10:30 amRoom: Virginia SuiteLocal Delivery of Chemical Gene Therapy – Mechanisms, Quantitative Understanding and Applications of Biodegradable CarriersChairErnst Wagner, PhDSpeakersLonnie D. Shea, PhDLocalized Gene Delivery by Biomaterial ImmobilizationBiomaterials are combined with gene delivery to provide a structure that guides cell growth, while also inducing the expression of inductive factors that drives the cellularprocesses leading to functional tissues. We have investigated immobilization of gene therapy vectors to biomaterials as a means to maintain the vectors locally, co-localizethe vectors to the surface for cell adhesion, and stabilize the vectors against degradation. The design principles we have developed for hydrogels and microporous scaffoldswill be presented, as well as their use with in vitro tissue models and in vivo regeneration. These biomaterial scaffolds provide opportunities to enhance or control genetransfer relative to more traditional delivery methods (e.g., injection), and provide an enabling technology to molecularly dissect tissue formation or to promote functionaltissue regeneration.Aliasger K. Salem, PhDPulsatile Release of Biomolecules from Polydimethylsiloxane ChipsCytosine-phosphorothioate-guanine oligodeoxynucleotides (CpG ODN) is a recent class of immunostimulatory adjuvants that includes unmethylated CpG dinucleotidesequences similar to those commonly found in bacterial DNA. CpG ODN specifically triggers toll like receptor 9 (TLR9), which is found within phagoendosomes of antigenpresenting cells (APCs) such as dendritic cells (DCs). CpG ODN triggers activation and maturation of DCs and helps to increase expression of antigens. CpG ODN can beused to induce polarized Th1 type immune responses. We have shown that antigens and CpG ODN must be co-delivered to generate the most potent therapeutic antigenspecificimmune responses. We have developed a series of delivery vehicles to ensure co-delivery of antigens and CpG ODN to the same APCs and to significantly increaseuptake by APCs. These strategies can result in antigen-specific immune responses that are 5 to 500-fold greater than administration of antigen alone. The approaches wehave developed to achieve this include the utilization of conjugate molecules, multicomponent nanorods, biodegradable microparticles, cell-microparticle hybrids and finallypolydimethylsiloxane based pulsatile release chips.David M. Lynn, PhDA ‘Multilayered’ Approach to the Delivery of DNA: Exploiting the Structure of Polyelectrolyte Multilayers to Promote Surface-MediatedTransfection and Tunable Multi-Agent DeliveryMethods for the layer-by-layer deposition of oppositely charged polymers on surfaces can be used to fabricate ultrathin multilayered films (or ‘polyelectrolyte multilayers’)using a broad range of natural and synthetic materials, including DNA. If the individual components of these assemblies are designed appropriately, these methods alsoprovide opportunities to design thin films that provide control over the release of DNA and other agents from surfaces. This talk will describe recent work from our laboratoryon the design of new polymers and the fabrication of thin films and coatings that provide spatial and temporal control over the release of DNA from surfaces in vitroand in vivo. These methods provide tunable control over the surface-mediated release of DNA over periods ranging from several hours to several days, weeks, or months,and can also be used to fabricate nanostructured films with hierarchical structures that permit control over the release of two or more DNA constructs with separate,distinct, and predictable release profiles (e.g., rapid release of one DNA construct followed by the slower, sustained release of a second DNA construct). With furtherdevelopment, these approaches could contribute to the design of thin films and coatings capable of delivering precise and well-defined quantities of multiple different DNAconstructs (or combinations of DNA and other therapeutic agents) in a broad range of fundamental and applied contexts.Daniel G. Anderson, PhDCombinatorial Development of Biomaterials for Gene DeliveryHigh throughput, combinatorial approaches have revolutionized small molecule drug discovery. Here we describe our work on high throughput methods for developing andcharacterizing biomaterials for genetic therapy and cell therapy. We have developed automated methods allowing for rapid synthesis of 1000’s of biomaterials, as wellas the testing of their chemical, material, and biological properties. These methods have also been applied towards the development of new methods to control stem cellbehavior, as well as vehicles for drug delivery. In particular, these combinatorial libraries of different biomaterials have enabled new methods for non-viral gene therapyand siRNA delivery.Saturday, May 22 nd

68American Society of Gene & Cell TherapyProgram ScheduleScientific Symposium 4028:30 am - 10:30 amRoom: Delaware SuiteEngineered T Cells in the Clinic: Emerging Clinical and Regulatory IssuesChairJacqueline Corrigan-Curay, MD, JDSpeakersDaniel M. Takefman, PhDGene Modified Cell Based Therapies: FDA PerspectivesThe purpose of this presentation is to provide FDA perspectives on gene modified cell based therapies. This presentation will outline some key regulatory considerationsfor the clinical use of patient specific gene therapies, such as engineered T-cells. The emphasis with be on manufacturing considerations as unique issues arise whenmanufacturing these types of products for clinical use.Joy Cavagnaro, PhD, DABTLimitations of Preclinical Studies for Predicting Safety of Uniquely Human Specific TherapiesCarl H. June, MDProlonged Engraftment and Decade Long Safety Record of Engineered T CellsIncreasing data from pre-clinical experiments and pilot clinical trials illustrate the potential of engineered T cells for therapy of cancer, chronic infection and autoimmunity.A key issue facing the field has been limited persistence of engineered T cells in most trials. Our clinical data indicates that T cells engineered to express a chimeric antigenreceptors can exhibit long term survival, and that in HIV infected patients, engineered T cells have a considerable safety record.PanelHelen E. Heslop, MDMichel Sadelain, MD, PhDSteven A. Rosenberg, MD, PhDSaturday, May 22 ndScientific Symposium 4038:30 am - 10:30 amRoom: Marriott Ballroom Salon 1Mechanisms of Innate Immunity Influencing Gene TherapyChairDavid B. Weiner, PhDSpeakersValder Arruda, MD, PhDGene Therapy for Tolerance Induction in Large Animal ModelsThe formation of neutralizing antibodies (inhibitors) to clotting Factor VIII or FIX is a major safety concern on the development of novel therapies for hemophilia. Inhibitorformation renders the protein replacement ineffective resulting in both high morbidity and mortality. Therefore the prevention or eradication of inhibitors is of fundamentalimportance. To eliminate the presence of inhibitors in hemophilia, an immune tolerance induction strategy consisting of large amounts of FVIII/FIX injected on a dailybasis for long periods of time (months to years) results in variable success rates. We will review gene-based strategies to prevent inhibitor formation in inhibitor-pronedogs. Notably, recent evidence demonstrates the possibility of the use of gene-based therapy for the eradication of preexisting inhibitors to FVIII from studies in hemophiliaA dogs. Emerging evidence on the role of T regulatory cells in modulating immune responses to the therapeutic protein now endogenously expressed by gene therapyopens a novel potential application of gene therapy, not only to prevent, but also to eradicate inhibitors in hemophilia and other diseases.EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 69Program ScheduleYiping Yang, MD, PhDInnate Immunity in AAV-mediated Gene TherapyRecombinant adeno-associated viruses (AAVs) have been used widely for in vivo gene therapy. However, adaptive immune responses to AAV have posed a significanthurdle in clinical application of AAV vectors. Recent advances have suggested a crucial role for innate immunity in shaping adaptive immune responses. Here I will discusshow AAV activates the innate immune system and the potential implications for improving the outcome of AAV-mediated gene therapy.David B. Weiner, PhDHigh Immune Potency of Highly Optimized EP DNA Vaccines in Animal Models and HumansDNA vaccines are an important emerging vaccine technology, however the immune responses induced by past generations of DNA vaccines were poor in larger animalsincluding nonhuman primates and importantly humans. We have recently utilized a combination of technologies for plasmid optimization, combined with enhanced EPdelivery to dramatically improve the immune potency of this platform. These new EP systems also offer improved tolerability and effectiveness. We will present data inanimal models and humans illustrating immune aspects of the technology for application to human infectious diseases.Michael T. Lotze, MDMicroRNAs in Immune Regulation-Opportunities for Cancer Gene TherapyInitially considered as means to regulate tissue differentiation and disordered in cancer, miRNAs [miR] have now been identified that are induced in response to hypoxia,oncogenic signaling, pathogens and tissue damage or injury. Each miR can regulate the translation of up to 100 separate mRNAs. Means to either express or knockdownmiRNA expression [so-called antagomiRs] have been operationalized in murine models and represent exciting novel targets for modifying immunity.Scientific Symposium 4048:30 am - 10:30 amRoom: Wilson ABCMicroRNA and siRNA Roles in Disease Progression and Development of Novel Therapeutic TargetsChairMaria G. Castro, PhDSpeakersAnna M. Krichevsky, PhDMicroRNAs as Targets for Glioma TherapyMicroRNA (miRNA) is a class of small RNA molecules involved in the regulation of expression of at least 30% of human genes and, therefore, it controls all principalcellular processes, including cell division and cell death. In my talk, I will describe our approach to reveal key miRNA regulators in human diseases and focus on miRNAfunctions in the development of human brain tumors. Our recent work presents proof-of-principles that specific inhibition of a single oncogenic miRNA could provide a noveltherapeutic approach for physiological modulation of multiple proteins whose expression and activity is de-regulated in cancer. It also suggests a diagnostic potential forthis novel class of molecules.M. Maral Mouradian, MDMicroRNAs in Parkinson’s Disease and Other Neurodegenerative Disordersalpha-Synuclein is a key protein that accumulates in the brains of patients with Parkinson’s disease and related neurodegenerative disorders. Evidence from clinical geneticstudies, animal models and cell biologic experiments indicate that elevated levels of this protein are toxic. This presentation will discuss down-regulation of alpha-synucleinexpression by microRNA leading to neuroprotection.Sean E. Lawler, PhDMicroRNA Alterations and Functions in GlioblastomaMicroRNAs have recently emerged as important regulators of gene expression with potential therapeutic applications in many human diseases. We have identified extensivealterations in microRNA expression in the malignant brain tumor glioblastoma multiforme. We have shown that altered microRNAs play roles in proliferation, stemcell-like behavior, and glioma cell migration. This talk will focus on the underlying mechanisms of microRNA action in glioblastoma, and their therapeutic potential.Saturday, May 22 nd

70American Society of Gene & Cell TherapyProgram ScheduleAl Charest, PhDNanoparticle-Mediated Delivery of siRNA in a Pre-Clinical Mouse Model of Glioblastoma MultiformeSmall interfering RNAs mediate cleavage of specific, complementary mRNA sequences and thus regulate gene expression. Not surprisingly, their use for treatment ofdiseases that are rooted in aberrant gene expression, such as cancer, has become a paradigm that has gained wide interest. We utilized dendrimer-conjugated magnetofluorescentnanoparticles to deliver anti-EGFR siRNA in vivo in an EGFR-driven transgenic model of glioblastoma. These nanoparticles were well tolerated in the CNS anddemonstrated specific and significant suppression of EGFR expression by convection-enhanced delivery to the mouse brain. Our data demonstrate the feasibility of siRNAdelivery in animals using a nanoplatform to efficiently knockdown target proteins.Scientific Symposium 4058:30 am - 10:30 amRoom: Marriott Ballroom Salons 2 & 3Special Considerations with Using Viral Vectors for Gene Modification of Stem CellsChairPhilip D. Gregory, PhDSpeakersMatthew Hirsch, PhDThe AAV Induced DNA Damage Response in Human Pluripotent CellsThe ability to genetically engineer stem cells ex vivo, then re-introduce them into a host for therapeutic purposes is an attractive approach for a variety of human geneticdiseases. Critical in this process is the ability to efficiently deliver transgenic DNA into the nucleus of stem cells in a manner that is well tolerated by the cell and withoutextensive host chromosome integration. A concern at the cellular level is the characterization of the cell type modified, and in particular, understanding the relationshipbetween “stemness” and oncogenesis. For example, the DNA damage response of pluripotent human embryonic stem cells (hESCs), in general, differs from that ofdifferentiated cells in that checkpoint functions are impaired and that these cells appear primed for rapid apoptosis. In this work, incidentally, we demonstrate that theadeno-associated virus (AAV) origin of replication, found ubiquitous in nature and currently used in human clinical trials for DNA delivery, induces a rapid, specific, andcomplete apoptotic response following transduction of non-differentiated hESCs. Cell cycle analysis by flow cytometry suggested that AAV-infected hESCs fail to induce aG1 checkpoint response and display an accumulation of cells in early S phase followed by apoptosis, suggesting that the AAV ITRs mimic stalled replication forks and/orperhaps uncapped telomeres. In contrast to reports of AAV-induced apoptosis in p53-deficient cancers, hESCs depleted of p53 survived significantly longer following AAVinfection than the parental control. Collectively, these data demonstrate that the AAV origin of replication (present on all AAV vectors) induces a lethal signaling cascadeduring S-phase in hESCs and a subsequent p53-dependent apoptotic response. This unexpected phenomenon is the first report of AAV vector toxicity in a wild type humancell and is reminiscent of previous reports of toxicity in p53-deficient cancers cells following AAV transduction. Understanding such unique DNA damage responses in stemcells and cancers following DNA delivery is necessary for optimization of conditions for efficient genetic engineering and safety in cell replacement therapies.Saturday, May 22 ndPhilip D. Gregory, hDStem Cell Modification with Zinc Finger NucleasesFrederic Paques, PhDMeganucleases and Viral Vectors: Alternative or Complementary ApproachesTargeted approaches have emerged today as an alternative to current random insertion strategies for gene therapy. Meganucleases, the most specific natural endonucleasesrepresent ideal tools for targeted genome editing, or “genome surgery”. Natural as well as engineered can be used to induce up to 20% of gene insertion into chosenhuman genes. The introduction of meganucleases into different cell types can be achieved by various means, including viral and non viral vectorization.Andrew M. Scharenberg, MDGene Editing Using Lentiviral Expression of Homing EndonucleasesGene editing and targeted integration approaches to gene therapy offer the potential to avoid idiosyncratic side effects associated with the random integration ofpromoter/gene cassettes in traditional gene therapy. The Northwest Genome Engineering Consortium is exploring the development of lentiviral vector-mediated expressionof homing endonucleases for gene editing and targeted integration in hematopoietic cells. Preliminary data on the efficacy of this approach in cultured and primaryhematopoietic cell models will be presented, and challenges and future directions in the field will be discussed.Break10:30 am – 11:00 amEXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 71Program ScheduleOral Abstract Session 41011:00 am - 1:00 pmRoom: Delaware SuiteMusculo-skeletal Gene & Cell TherapyCo-ChairsJeffrey Chamberlain, PhD & Paula Clemens, MD(Abstracts 580-587; see page 122)Oral Abstract Session 41111:00 am - 1:00 pmRoom: Virginia SuiteChemical and Molecular ConjugatesCo-ChairsHideyoshi Harashima, PhD & Millicent O. Sullivan, PhD(Abstracts 588-595; see page 122)Oral Abstract Session 41211:00 am - 1:00 pmRoom: Wilson ABCCardiovascular Gene & Cell TherapyCo-ChairsRoger J. Hajjar, MD & Xiao Xiao, PhD(Abstracts 596-603; see page 123)Oral Abstract Session 41311:00 am - 1:00 pmRoom: Marriott Ballroom Salons 2 & 3Cancer-Oncolytic Viruses IICo-ChairsRonald Rodriguez, MD, PhD & Masato Yamamoto, MD, PhD(Abstracts 604-611; Abstract 605 withdrawn; Abstract 191 moved from Poster Session I; see page 123)Oral Abstract Session 41411:00 am - 1:00 pmRoom: Maryland SuiteHematologic/Immunologic: Clinical, Preclinical and SafetyCo-ChairsGay Crooks, MD & Adrian J. Thrasher, MD, PhD(Abstracts 612-619; see page 124)Saturday, May 22 nd

72American Society of Gene & Cell TherapyProgram ScheduleOral Abstract Session 41511:00 am - 12:00 pmRoom: Thurgood Marshall WLung and Respiratory Disease Gene & Cell TherapyCo-ChairsTerence R. Flotte, MD & Maria Limberis, PhD(Abstracts 620-623; see page 124)Oral Abstract Session 41612:15 pm - 1:15 pmRoom: Thurgood Marshall WGene RegulationCo-ChairsOlivier Danos, PhD & Giuliana Ferrari, PhD(Abstracts 624-627; see pages 124-125)Oral Abstract Session 41711:00 am - 1:00 pmRoom: Marriott Ballroom Salon 1Stem Cell TherapiesCo-ChairsCarolyn Lutzko, PhD & Alice F. Tarantal, PhD(Abstracts 628-635; see page 125)Lunch Break1:00 pm – 3:00 pmMeet-the-Investigator Lunch 4201:00 pm - 2:15 pmRoom: Balcony AStem CellsSpeakersJames Ellis, PhD & Carolyn Lutzko, PhDSaturday, May 22 ndMeet-the-Investigator Lunch 4211:00 pm - 2:15 pmRoom: Balcony BRoles of miRNAsSpeakersMark A. Kay, MD, PhD & Luigi M. Naldini, MD, PhDEXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 73Program ScheduleOral Abstract Session 4303:00 pm - 5:00 pmRoom: Maryland SuiteAdenovirus and Other DNA Virus VectorsCo-ChairsAnja Ehrhardt, PhD & Florian Kreppel, PhD(Abstracts 636-643; see pages 125-126)Oral Abstract Session 4313:00 pm - 5:00 pmRoom: Delaware SuiteInfectious Diseases and VaccinesCo-ChairsAnn Leen, PhD & Bruce E. Torbett, PhD, MSPH(Abstracts 644-651; see page 126)Oral Abstract Session 4323:00 pm - 5:00 pmRoom: Marriott Ballroom Salons 2 & 3Cancer – Immunotherapy IICo-ChairsStephen Gottschalk, MD & David B. Weiner, PhD(Abstracts 652-659; see pages 126-127 )Oral Abstract Session 4333:00 pm - 5:00 pmRoom: Thurgood Marshall WOligonucleotide & RNAi Therapeutics IICo-ChairsPaloma H. Giangrande, PhD & Peter M. Glazer, MD, PhD(Abstracts 660-687; see page 127)Oral Abstract Session 4343:00 pm - 5:00 pmRoom: Marriott Ballroom Salon 1Cell Processing and Vector ProductionCo-ChairsStephen M. Kaminsky, PhD & J. Fraser Wright, PhD(Abstracts 668-675; see pages 127-128)Saturday, May 22 nd

74American Society of Gene & Cell TherapyProgram ScheduleOral Abstract Session 4353:00 pm - 5:00 pmRoom: Wilson ABCGene Therapy for Inborn Errors of MetabolismCo-ChairsDwight Koeberl, MD, PhD & Brendan Lee, MD, PhD(Abstracts 676-683; see page 128)Oral Abstract Session 4363:00 pm - 5:00 pmRoom: Virginia SuiteLate Breaking SessionCo-ChairsGuangping Gao, PhD & Stanton L. Gerson, MD(Abstracts 914-921; see pages 128-129)Poster Hall Social (use your drink ticket at tonight's social)5:00 pm – 6:00 pmRoom: AtriumSaturday, May 22 ndPoster Session III6:00 pm – 8:00 pmRoom: Exhibit Hall CRNA Virus Vectors II(Abstracts 684 through 696; see page 129)AAV Vectors III(Abstracts 697 through 711; see page 130)Adenovirus and Other DNA Virus Vectors III(Abstracts 712 through 725; see pages 130-131)DNA Vectorology & Gene Targeting(Abstracts 726 through 741; see pages 131-132)Chemical and Molecular Conjugates III(Abstracts 742 through 757; see pages 132-133)Genetic and Metabolic Diseases Gene & Cell Therapy III(Abstracts 758 through 772; Abstract 764 has been moved to Poster Session II after Abstract 422; see page 133)Neurodegenerative Disorders, Spinal Cord and Trauma(Abstracts 773 through 783; see page 134)Musculo-skeletal Gene & Cell Therapy III(Abstracts 784 through 796; see pages 134-135)Infectious Diseases and Vaccines: Non-Vaccine Related Gene Transfer Research(Abstracts 797 through 808; see pages 135-136)Cancer – Immunotherapy III(Abstracts 809 through 827; see pages 136-137)EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 75Program ScheduleCancer-Oncolytic Viruses III(Abstracts 828 through 842; Abstract 838 withdrawn; see page 137)Cancer-Targeted Gene & Cell Therapy III(Abstracts 843 through 856; see pages 137-138)Hematologic and Immunologic Gene & Cell Therapy III(Abstracts 857 through 871; Abstract 869 has been move to Poster Session I after Abstract 233; see pages 138-139)Lung and Respiratory Disease Gene & Cell Therapy(Abstracts 872 through 881; see pages 139-140)Oligonucleotide & RNAi Therapeutics III(Abstracts 882 through 897; see pages 140-141)Stem Cell Therapies(Abstracts 898 through 913; see page 141)Late Breaking Science III(Abstracts 938 through 947; see page 142)Annual Meeting ConcludesSaturday, May 22 nd

76American Society of Gene & Cell TherapyExhibit Hall Floor PlanASGCT 2010 Annual MeetingMay 19-22, 2010 • Marriott Wardman Park Hotel • Washington, DCSpeaker Ready RoomRegistrationEXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 77Exhibitor DescriptionsAldevron3233 15 th Street, SouthFargo, ND 58104Telephone: (701) 297-9256Fax: (701) 280-1642E-mail: miller@aldevron.comWebsite: www.aldevron.comBooth Number: 506Aldevron is a leading contract manufacturing organization specializing in plasmidDNA, protein, antibody, DNA vaccine screening and genetic immunization(GIA) services. We manufacture biologics for research, clinical, and diagnosticapplications including ready-to-use AAV helper, cytokine, and reporter plasmids.Aldevron’s capacity and throughput capabilities support any project in bacterial,insect, and mammalian cell systems. By combining innovative technologies withbest-in-class project management, our team ensures that we consistently exceedyour expectations.American Society of Gene & Cell Therapy555 East Wells StreetSuite 1100Milwaukee, WI 53202Telephone: (414) 278-1341Fax: (414) 276-3349E-mail: info@asgct.orgWebsite: www.asgct.orgBooth Number: 609 & 611Stop by the ASGCT membership booth to pick-up your Abstracts-on-Disc and theEducation Session CD. Find out where the 2011 Annual Meeting will be heldand other Society information.Biologics Consulting Group, Inc.1317 King StreetAlexandria, VA 22314Telephone: (703) 739-5695Fax: (703) 548-7457E-mail: mhawkins@bcg-usa.comWebsite: www.bcg-usa.comBooth Number: 401Biologics Consulting Group, Inc., is an international firm providing regulatoryand product development advice on the development and commercialization ofbiologicals, drugs, devices, diagnostics, and combination products. Since 1993,we have helped hundreds of products reach the marketplace. Our consultantscome from the executive/senior tiers of FDA and industry.BioSpherix, Ltd.19 Demott St.Lacona, NY 13083Telephone: (315) 387-3414Fax: (315) 387-3415E-mail: kmurray@biospherix.comWebsite: www.biospherix.comBooth Number: 210Closed-incubation-system for clinical cell cultures. Multiple, independent, highperformance, O2/CO2 incubators open into aseptic isolation modules with identicalcontrolled atmospheres for uninterrupted conditions during cell handling. Can bea cGMP compliant mini-facility, offering cell and gene therapists an economical andpractical alternative to expensive brick-and-mortar walk-in clean rooms.Caliper Life Sciences68 Elm StreetHopkinton, MA 01748Telephone: (508) 435-9500Fax: (508) 435-3439Website: www.caliperls.comBooth Number: 514Caliper Life Sciences is a leading supplier of tools and services for life scienceresearch including IVIS in vivo imaging systems. IVIS is the most publishedplatform for sensitive fluorescence and bioluminescence imaging in both 2D and3D providing the insight to view complex biological interactions such as geneexpression or stem cell engraftment in longitudinal studies of whole animals.Center for Cellular and Molecular Therapeutics at theChildren’s Hospital of PhiladelphiaRoom 5000Colket Translational Research Building3501 Civic Center Blvd.Philadelphia, PA 19104Telephone: (267) 426-5256Fax: (215) 590-3660E-mail: sunj@email.chop.eduBooth Number: 313

78American Society of Gene & Cell TherapyExhibitor DescriptionsData Unlimited International, Inc.15881-B Crabbs Branch WayRockville, MD 20855Telephone: (240) 631-7933Fax: (240) 631-7937E-mail: contact@duii.comWebsite: www.duii.comBooth Number: 211Starfruit Technologies® is software/database/computer/barcode for DNAdiagnostic, genome/cancer research, immunogenetic labs – enables sample,patient, biorepository, billing databases; mutation, variant, disease, genotypedatabases, SNP databank; instrument interface, barcode, electronic signature,QA/QC; worksheet, workflow, inventory, protocol, image; epidemiologicalfrequency, trend, geographical distribution, disease/disorder susceptibility,reporting; comply with 21CFR11, CAP, CLIA, HIPPA, PHI.Elsevier - Academic Press15807 Quince Orchard RoadN. Potomac, MD 20878Telephone: (240) 477-8564Fax: (240) 477-8571E-mail: b.karafin@elsevier.comBooth Number: 406As the world’s leading publisher of science and health information, Elsevierserves more than 30 million scientists, students, and health and informationprofessionals worldwide. Visit Elsevier for the latest clinical trial resources, suchas: Clinical and Translational Science: Principles of Human Research by DavidRobertson and Gordon H. Williams.Exemplar Genetics958 N. MainSioux Center, IA 51250Telephone: (712) 722-2767Fax: (712) 722-2126E-mail: troy.arends@exemplargenetics.comWebsite: www.exemplargenetics.comBooth Number: 408Exemplar Genetics is enabling discovery through the creation of large animalmodels of human disease. Through proprietary techniques and licensedprocesses, we have been successful in creating the only commercially availablelarge animal model that replicates human disease. These techniques can beutilized to create models of interest in any field.Institutional Biosafety Committee Services (IBC Services)2103 Harrison Av NWPMB 2436Olympia, WA 98502-2607Telephone: (360) 252-2850Fax: (360) 252-2820E-mail: ibcs@wirb.comWebsite: www.ibcservicepoint.comBooth Number: 505IBC Services establishes and provides administrative support for local IBCsreviewing gene transfer clinical trials and related rDNA research. We have servedmedical practices, hospitals and health systems, and VA and university settingsin 46 states and abroad. Broad experience from first-in-human and single-subjectprotocols to multicenter late-phase trials.Lovelace Respiratory Research Institute2425 Ridgecrest Dr. SEAlbuquerque, NM 87108Telephone: (505) 348-9457/9557Fax: (505) 348-4983E-mail: JBenson@LRRI.orgWebsite: www.lrri.orgBooth Number: 307The Lovelace Respiratory Research Institute is a private not-for-profit biomedicalresearch organization. Lovelace offers animal models of disease, evaluation ofefficacy of potential new therapeutics, and pre-clinical assessments includingevaluation of pharmacokinetics/biodistribution in large and small animalmodels. Studies are routinely performed under GLP guidelines.Mary Ann Liebert, Inc.140 Huguenot StreetNew Rochelle, NY 10801Telephone: (914) 740-2100Fax: (914) 740-2101E-mail: info@liebertpub.comWebsite: www.liebertpub.comBooth Number: 510Mary Ann Liebert, Inc., publishes authoritative peer-reviewed journals in newand promising areas of science and biomedical research including Human GeneTherapy, (www.liebertpub.com/hum), named one of the 100 most influentialJournals in Biology & Medicine over the last 100 years! Visit us @ booth#510.EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 79Exhibitor DescriptionsMeridian Life Science, Inc.3471 River Hills DriveCincinnati, OH 45244Telephone: (513) 271-3700Fax: (513) 271-3762E-mail: Shirley.Torrence@meridianbioscience.comWebsite: www.meridianlifescience.comBooth Number: 208MLS provides contract R&D, process development, and clinical cGMPbiomanufacturing for vaccines, viral challenge materials, vectored genetherapies, VLPs, and r-proteins from BEVS. With over 25 yrs. of cell culture, virusproduction, protein purification, assay development and regulatory experience,MLS is your trusted partner for preclinical to Phase I/II manufacturing.Molmed S.p.AVia Olgettina, 58Milan, Italy 20132Telephone: +39 0221277257Fax: +39 0221277325E-mail: simona.laseta@molmed.comWebsite: www.molmed.comBooth Number: 209MolMed is a medical biotechnology company with a primary focus on developingnovel cell/gene therapies for treating cancer. The in-house GMP facility allowedMolMed to be involved in projects as GMP manufacturer. We are glad to offeryou our solutions for GMP cell/gene therapy, from early stage to advancedclinical development.Nanosight6660 N. High Street, Suite 2AWorthington, OH 43085Telephone: (614) 888-0023Fax: (614) 987-0045E-mail: jim.munhall@nanosight.comWebsite: www.nanosight.comBooth Number: 405Nanosight develops and manufactures instruments for Counting, Sizing andVisualizing Nanoparticles from 10 nm to 2.0 µm. Our unique NanoparticleTracking Analysis (NTA) technology allows for the measurement of DiffusionCoefficients of individual nanoparticles or viruses and determines the Count,Size & Concentration of the particle dispersions. Polydispersed and multi-modalsamples are quickly identified and resolved. Direct Visualization of the dispersionbeing measured is displayed and a video of the particles being measured iscreated and stored along with the size distribution data. Options are available forfluorescence measurements.National Gene Vector Biorepository980 West Walnut Street, R3 C602Indianapolis, IN 46202Telephone: (317) 274-4519Fax: (317) 278-3327E-mail: lrubin@iupui.eduWebsite: https://www.ngvbcc.orgBooth Number: 512The National Gene Vector Biorepository provides support for gene therapy researchby offering several services. Check out the reagent repository comprising celllines, plasmids and other tools used in gene therapy research. There are archivingservices to meet FDA requirements. The NGVB will store clinical post-trial samples,final product reserves, and master cell banks as well as pharmacology/toxicologysamples. A pharm/tox database containing gene therapy tox studies is a valuableresource. We offer assistance with insertional mutagenesis analysis through theSeqMap Bioinformatic Tool as well as LAM-PCR and other testing services. Go tohttps://www.ngvbcc.org or come and see us in Booth 512.Nature Publishing Group75 Varick Street, 9th floorNew York, NY 10013Telephone: (212) 726-9200Fax: (212) 696-9006E-mail: n.neysmith@us.nature.comWebsite: www.nature.comBooth Number: 206Nature Publishing Group brings leading scientific and medical research to yourdesk top. The NPG portfolio combines the continued excellence of Nature, itsassociated research and review journals, and over 45 leading academic andsociety journals in the life, physical and clinical sciences. Visit Booth Number 206for free sample copies.Nature Technology Corporation4701 Innovation Dr.Lincoln, NE 68521Telephone: (402) 472-6530Fax: (402) 472-6532E-mail: natx@natx.comWebsite: www.natx.comBooth Number: 400Nature Technology Corporation is a discovery-based bioengineering technologycompany, providing industry solutions for DNA-based gene therapeutics and DNAvaccines development, including: design, manufacturing, testing, and tech transferof best-in-class vectors for in vivo gene expression.

80American Society of Gene & Cell TherapyExhibitor DescriptionsNexcelom Bioscience360 Merrimack StreetBldg 9Lawrence, MA 01843Telephone: (978) 327-5340Fax: (978) 327-5341E-mail: ddemers@nexcelom.comWebsite: www.nexcelom.comBooth Number: 414Nexcelom’s Cellometer line of simple-to-use cell counters automate manual cellcounting procedures by obtaining accurate counts, viability, and cell sizes in lessthan 30 seconds & only 20uL of sample. Fluorescence detection capabilitiesenable fast & simple determination of GFP transfection rates, PI-viability, &direct counting of WBCs without lysing.NHLBI Gene Therapy Resource ProgramNational Heart, Lung, and Blood Institute, NIH2 Rockledge Center – 6701 Rockledge DriveBethesda, MD 20892-7940Telephone: (301) 435-0477Fax: (301) 480-7971E-mail: gtrpccc@s-3.comWebsite: www.gtrp.orgBooth Number: 311The NHLBI Gene Therapy Resource Program (GTRP) facilitates the translationof gene therapy research into clinical applications primarily in heart, lung, andblood diseases. Services provided by the program include preclinical and clinicalgradevector production, pharmacology/toxicology testing, immunology testing,regulatory support, and clinical trial funding assistance.NIH Office of Biotechnology Activities6705 Rockledge DriveSuite 750Bethesda, MD 20892Telephone: (301) 496-9838Fax: (301) 496-9839E-mail: oba@od.nih.govWebsite: http:\\oba.od.nih.govBooth Number: 508The NIH Office of Biotechnology Activities (OBA) promotes science, safety, andethics in biotechnology through advancement of knowledge, enhancementof public understanding, and development of sound public policies. OBAaccomplishes its mission through analysis, deliberation, and communication ofscientific, medical, ethical, legal, and social issues.NIH-RAID6001 Executive Blvd, Room 2141Bethesda, MD 20892Telephone: (301) 594-4660Fax: (301) 402-1501E-mail: nih-raid@mail.nih.govWebsite: http://nihroadmap.nih.gov/raid/Booth Number: 305NIH-RAID makes available, at no cost, certain resources needed for thedevelopment of new therapeutic agents. Available services include: production,bulk supply, GMP manufacturing, formulation, development of an assay suitablefor pharmacokinetic testing, and animal toxicology. NIH-RAID is not a grantprogram; successful projects gain access to government contract resources.Omnia Biologics, Inc.12111 Parklawn DriveRockville, MD 20852Telephone: (301) 984-5928Fax: (301) 984-2515E-mail: scardak@omniabiologics.comWebsite: www.omniabiologics.comBooth Number: 212Omnia Biologics provides cost effective outsourcing of product developmentservices to the biotechnology, pharmaceutical, and academic biologic drugdevelopers. These services include process development, cGMP cell and virusbanking, comprehensive cGMP manufacturing services, BSL-3 containment,assay development, formulation and fill/finish. Omnia has experience with avariety of vaccine, gene therapy and protein therapeutic platforms.Penn Vector Core125 South 31 st Street, Suite 2000Philadelphia, PA 19104-3403Telephone: (215) 573-0633Fax: (215) 573-0300E-mail: vector@mail.med.upenn.eduWebsite: http://www.med.upenn.edu/gtp/vector_core.shtmlBooth Number: 309Penn Vector Core is a state-of-the-art vector production facility for investigatorsboth within and external to the University of Pennsylvania. The main objective ofthe Core is to make various types of high quality viral vectors for gene transfer/Vaccine studies at the preclinical and basic research level.EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 81Exhibitor DescriptionsPhilips Research345 Scarborough RoadBriarcliff Manor, NY 10510Telephone: (914) 945-6188Fax: (914) 945-6580E-mail: ralf.seip@philips.comWebsite: www.research.philips.com/TIPSBooth Number: 501Philips Research has developed the Therapy Imaging Probe System (TIPS)device. TIPS is a turnkey solution for all pre-clinical research needs using focusedultrasound for non-invasive gene delivery/transfection and site-targeted drugdelivery using ultrasound and microbubble agents.Polyplus-transfectionBioparc Bd S. BrantIllkirch, Alsace67401FranceTelephone: +33390406180Fax: +33390406181E-mail: support@polyplus-transfection.comWebsite: www.polyplus-transfection.comBooth Number: 507Polyplus-transfection is a Biotech company dedicated to the R & D andmarketing of transfection reagents. Polyplus provides state-of-the-art qualityreagents for standard in vitro DNA transfection to human gene therapy, aswell as for protein production in synthetic medium, siRNA delivery and proteindelivery in living cells.Puresyn, Inc.87 Great Valley ParkwayMalvern, PA 19355Telephone: (610) 640-0800Fax: (610) 640-0808E-mail: cflynn@puresyn.comWebsite: www.puresyn.comBooth Number: 308Puresyn, Inc., is a Separations and Purification Technology Company thatdevelops, manufactures and markets state-of-the-art products and contractmanufacturing services for nucleic acids and other biological molecules utilizingour proprietary polymer technology, PolyFlo ® for production and purification ofgene delivery products including plasmids and recombinant viruses at scales andcustomized specifications.ReGenX Biosciences750 17th St. NWSuite 1100Washington, DC 20006Telephone: (202) 785-7438Fax: (202) 785-7439E-mail: sales@regenxbio.comWebsite: www.regenxbio.comBooth Number: 407ReGenX is a research and development stage biopharmaceutical companydeveloping novel therapeutics and research tools based on adeno-associated viralvectors, or AAV vectors.Sartorius Stedim North America Inc.5 Orville DriveBohemia, NY 11716Telephone: (800) 368-7178Fax: (631) 254-2453E-mail: btcs@sartorius-stedim.comWebsite: www.sartorius-stedim.comBooth Number: 306Sartorius Stedim Biotech is a leading provider of equipment and servicesfor the development, quality assurance and production processes of thebiopharmaceutical industry as well as the public sector. With integrated solutionscovering fermentation, filtration, purification, fluid management, and labtechnologies, Sartorius Stedim Biotech focuses on single-use technologies andvalue-added services to meet requirements of the industries it serves.Seattle’s Convention and Visitors Bureau701 Pike Street, Suite 800Seattle, WA 98101Telephone: (206) 461-5800Fax: (206) 461-5855E-mail: visinfo@visitseattle.orgWebsite: www.visitseattle.orgBooth Number: 500Seattle is two cities in one. It’s a world-class metropolis set within, beautiful naturalsurroundings, offering the best of urban lifestyle while embracing the outdoors.Many of the city’s top visitor attractions are within mere blocks of the WashingtonState Convention Center, including Pike Place Market. Seattle is metronatural.

82American Society of Gene & Cell TherapyExhibitor DescriptionsSt. Jude Children’s Research Hospital262 Danny Thomas PlaceMemphis, TN 38105Telephone: (901) 595-2750Fax: (901) 595-5376E-mail: fellowships@stjude.orgWebsite: www.stjude.orgBooth Number: 207St. Jude Children’s Research Hospital is a non-profit biomedical researchinstitution located in Memphis, TN, in the United States where 190 basic scienceand clinical researchers investigate the molecular basis of both normal cellularand diseased processes. Visit our booth to discuss and apply for PostdoctoralFellowship positions for PhD, MD, PharmD, and DVM students.Techulon, Inc.2200 Kraft DriveSuite 2475Blacksburg, VA 24060Telephone: (415) 602-0481Fax: (206) 202-0418E-mail: frank.akers@techulon.comWebsite: www.techulon.comBooth Number: 613Techulon develops and markets biodegradable transfection reagents that exhibithigh efficacy and very low cytotoxicity, especially in sensitive primary cells.Techulon welcomes inquiries from researchers and from companies interested indeveloping therapeutic applications.Thermo Scientific Genomics601 Genome WaySuite 2100Huntsville, AL 35806Telephone: (256) 704-4848Fax: (256) 704-4849E-mail: Info.account@thermofisher.comWebsite: www.thermo.com/genBooth Number: 213The Thermo Scientific genomics portfolio, which includes Dharmacon and OpenBiosystems RNAi and gene expression technologies and ABgene PCR products,provides novel tools to help our customers unlock the underlying molecularmechanisms of disease from cancer, to diabetes to viral infection and developnew therapies to fight it.TriLink BioTechnologies, Inc.9955 Mesa Rim RoadSan Diego, CA 92121Telephone: (858) 546-0004Fax: (858) 546-0020E-mail: info@trilinkbiotech.comWebsite: www.trilinkbiotech.comBooth Number: 314TriLink BioTechnologies manufactures custom oligonucleotides, modifiednucleoside triphosphates and CleanAmp PCR products. In addition, customchemistry, contract research services and ISO/QSR compliant cGMP productionfacilities are offered. TriLink’s strong proficiency in nucleoside and oligonucleotidechemistry means high purity, modified compounds and expert technical support.For more information visit www.trilinkbiotech.com.Vandalia ResearchPO Box 2705Huntington, WV 25726-2705Telephone: (304) 529-0803Fax: (888) 550-8220E-mail: hughes@vandaliaresearch.comWebsite: www.vandaliaresearch.comBooth Number: 513VGXI, Inc.2700 Research Forest DriveSuite 180The Woodlands, TX 77381Telephone: (281) 296-7300E-mail: hhebel@vgxii.comWebsite: www.vgxii.comBooth Number: 607VGXI, Inc. has over 13 years experience manufacturing injectable-gradeDNA plasmids for gene therapy research. A leading contract manufacturingorganization (CMO), our fermentation services are designed to meet the uniqueneeds of gene therapy researchers at every stage of product development –from research to commercial supply. This comprehensive offering lets researchersavoid the risks associated with switching suppliers just prior to clinical trials. Ourmission is to support biomedical researchers in their effort to rid the world ofdeadly and debilitating diseases. We do this by leveraging our experience andpatented technologies to maximize our clients’ chances of clinical success.EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 83Exhibitor DescriptionsWaisman Clinical Biomanufacturing Facility1500 Highland AvenueMadison, WI 53705Telephone: (608) 263-8940E-mail: keach@waisman.wisc.eduWebsite: www.GMPbio.orgBooth Number: 214The Waisman Clinical Biomanufacturing Facility (WCBF) is a dedicated manufacturingfacility that provides cGMP manufacturing services for producing biotherapeuticsfor early-stage human clinical trials. Services that are provided by the WCBF rangefrom process development to clinical production and product fill and finish, all withfull quality system support.Wiley-Blackwell350 Main St.Malden, MA 02148Telephone: (800) 532-5954Fax: (781) 338-8552E-mail: jo.wright@wiley.comWebsite: www.wiley.comBooth Number: 413Wiley-Blackwell publishes quality journals in gene and cell therapy includingStem Cells, The Journal of Gene Medicine, and Journal of Tissue Engineeringand Regenerative Medicine, and must-read books including Immunology ofGene Therapy, Delivery Technologies for Biopharmaceuticals and Viral Therapy ofCancer. See our full collection at: www.wileyblackwell.com.

84American Society of Gene & Cell TherapyExhibitor InformationGeneral InformationThe Exhibit Hall is located in Exhibit Hall C of the Marriott Wardman Park Hotel.All participants are urged to allow adequate time in your daily schedule to visitthe exhibits. The companies, organizations and institutions exhibiting at theASGCT 13th Annual Meeting will be providing you with the latest informationon products and services directly related to your professional needs, as well asrecruiting for open positions.Exhibit DatesExhibits will be open Wednesday, May 19 through Friday, May 21, 2010.Exhibitor RegistrationThe Exhibitor Registration Desk is located in the atrium, right outside Exhibit Hall C.Exhibitor Registration Desk HoursWednesday, May 19 9:00 am – 7:00 pmThursday, May 207:00 am – 5:00 pmFriday, May 217:00 am – 5:00 pmExhibitor Badge PolicyAdmission to the Exhibit Hall will be by name badge only. Security guards willmonitor exhibit hall entrances for proper I.D. Exhibit booth personnel must showan official ASGCT exhibitor name badge in order to gain access to the exhibithall during installation, show, or dismantlement hours. Independent contractorpersonnel, hired by an exhibitor to install and dismantle their display, do notneed to show exhibitor badges, but should possess identification that they areemployed by the independent contractor. If independent contractors do notpossess proper identification, they should obtain a name badge at the on-siteexhibitor registration desk.Endorsement DisclaimerProducts and services displayed in the Exhibit Hall or advertised in this programoccur by contractual business arrangements between ASGCT and participatingcompanies and organizations. These arrangements do not constitute or imply anendorsement by ASGCT of these products and services.Exhibit InstallationWednesday, May 19Exhibit Hall HoursWednesday, May 19Thursday, May 20Thursday, May 20Friday, May 219:00 am – 5:00 pm7:00 pm – 9:00 pm9:15 am – 10:30 am6:15 pm – 8:15 pm6:30 pm – 8:30 pmDismantlementFriday, May 218:30 pm – 10:30 pmNote: All exhibit booths must be staffed during hall hours. Packing ofequipment/literature and the dismantling of exhibits will not be permitted untilafter 8:30 pm on Friday, May 21, 2010.EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 85Washington, DC Fun FactsIn Washington, DC, you’ll enjoy access to fascinating, FREE attractions andhistoric sights. Touch a moon rock, marvel at the Hope Diamond, view Dorothy’sRuby Red slippers or explore Native American culture at the SmithsonianInstitution’s fifteen Washington, DC area facilities. Discover treasures like theGutenberg Bible at the Library of Congress, the only da Vinci painting in NorthAmerica at the National Gallery of Art and historic documents like the Declarationof Independence at the National Archives. The National Zoo is also located withinwalking distance of the Marriott Wardman Park Hotel.Away from these celebrated federal sites, Washington, D.C. unwinds into afascinating network of neighborhoods where visitors discover trendy boutiques,hip bars and restaurants, plus art galleries, historic homes and lush parks andgardens. Shoppers love the store-lined streets of Georgetown, while jazz musicfans won’t want to miss a trip to U Street, where Duke Ellington played his firstnotes. The city’s international character shines through in its Adams Morganand Dupont Circle neighborhoods, two prime destinations for eclectic dining andnightlife and the historic center of the city’s embassy community.The arrival of several new eateries has made the nation’s capital a primedestination for dining out, with many of the city’s top tables located in thedowntown Penn Quarter neighborhood. DC is also earning new recognition as athriving performing arts town, with 65 professional theatre companies based inthe metropolitan area presenting edgy world premieres and celebrated Broadwaymusicals throughout the year.It’s easy to get around town thanksto DC’s pedestrian-friendly streets andits safe, efficient public transportationsystem—including Metrorail and the newCirculator bus—it’s easy to get from yourhotel to Washington, DC’s attractions. Formore information, visit www.washington.org.Hotel InformationMarriott Wardman Park Hotel2660 Woodly Road NWWashington, DCPhone: (202) 328-2000The hotel has several places you can grab a bit to eat, which include:Harry’s Pub:This Washington DC restaurant features an Old English menu. Enjoysandwiches, soups, pizzas and microbrews. Open for lunch and dinner.Illy’sGrab a bite to go at this coffeehouse featuring specialty coffees, teas andfresh baked goods.Stone’s Throw Restaurant & Bar:A steakhouse offering steaks, chops and seafood dishes that is open forbreakfast, lunch and dinnerWoodley’s MarketThis gourmet deli serves breakfast items, snacks and gourmet takeoutsandwiches and meals.Or walk through the neighborhood and enjoy over 20 eatery options.

86American Society of Gene & Cell TherapyAbstract DirectoryThursday, May 20 thThursday, May 20, 2010Oral Abstract Session 230AAV Vectors: Vector Trafficking2:00 PM - 4:00 PMRoom: Marriott Ballroom: Salons 2 & 31 2:00 PMEngineering AAV for Improved In Vitro Infectivity, In Vivo Tropismand Onset of ExpressionRu Xiao, Sadik H. Kassim, Lauren E. Mays, Deirdre McMenamin, Regina Munden, JamesM. Wilson, Luk H. Vandenberghe.2 2:15 PMTargeting Directed Evolution of AAV Capsids for Specific TherapeuticApplicationsSteven J. Gray, Bonita L. Blake, Matthew Hirsch, Hugh E. Criswell, Sarah Nicolson,Wuping Li, Thomas J. McCown, R. Jude Samulski.3 2:30 PMEnhanced Hepatic Transgene Expression Following IntravenousDelivery of Novel Stem Cell-Derived Recombinant AAV VectorsLaura J. Smith, Ariel Kauss, Kamehameha K. Wong, Saswati Chatterjee.4 2:45 PMAAV Capsid Sequence Significantly Influences Intracellular ViralTrafficking in Polarized Human Airway Epithelial CellsNicholas W. Keiser, Ziying Yan, Diana Lei-Butters, John F. Engelhardt.5 3:00 PMCell Entry Pathway Defines Efficiency and Specificity of rAAVTargeting VectorsSilke Uhrig, Jessica Sallach, David Gomez Almarza, Luca Perabo, Sabine Eming,Fernando Laguzzi Larcher, Michael Hallek, Hildegard Büning.6 3:15 PMNovel Cardiac-Tropic AAV Vectors by DNA Shuffling and In VivoScreeningZhenhua Yuan, Lin Yang, Chunping Qiao, Juan Li, Xiao Xiao.7 3:30 PMIntravenously Administered rAAV9 Vector Efficiently TransducesTissues In Vivo Via Caveolin-1-Independent Transport across theCapillary Endothelial Cell BarrierKei Adachi, Nicole M. Kotchey, Maliha Zahid, Hiroyuki Nakai.8 3:45 PMDirected Evolution of Adeno-Associated Virus Variants That EvadeHuman Neutralizing AntibodiesDaniel Stone, James T. Koerber, Federico Mingozzi, Gregory M. Podsakoff, KatherineHigh, David V. Schaffer.Oral Abstract Session 231DNA Vectorology & Gene Targeting2:00 PM - 4:00 PMRoom: Maryland Suite9 2:00 PMA Simplified Approach for Robust Minicircle DNA Vector ProductionUsing a New Genetically-Modified E. Coli Producer StrainZYCY10P3S2TZhi-Ying Chen, Cheng-Yi He, Mark A. Kay.10 2:15 PMTargeted Transgene Integration in Epidermal Stem Cells by Zinc FingerNucleases and Integrase-Defective Lentiviral VectorsGiulietta Maruggi, Angelo Lombardo, Francesca Miselli, Pietro Genovese, Michael C.Holmes, Philip D. Gregory, Alessandra Recchia, Fulvio Mavilio, Luigi Naldini.11 2:30 PMZinc Finger Nucleases Drive Efficient Gene Disruption and Site-Specific Gene Addition in Human HSCNathalia G. Holt, Kevin G. Haworth, Kathleen C. Burke, Jianbin Wang, Kenneth Kim,Geoffrey Friedman, Philip D. Gregory, Michael C. Holmes, Paula M. Cannon.12 2:45 PMManipulating piggyBacTransposon Chromosomal Integration Site-Selection in Human CellsClaudia Kettlun, Daniel Galvan, Aparna Kaja, Edward Rebar, Matthew H. Wilson.13 3:00 PMOptimized Recovery of Integration Sites from Gene-Modified CellsUsing Mu Transposition In VitroTroy L. Brady, Nirav Malani, Gary P. Wang, Charles C. Berry, Philippe Leboulch, SalimaHacein-Bey-Abina, Marina Cavazzana-Calvo, Harri Savilahti, Frederic D. Bushman.14 3:15 PMAn In Vitro-Identified High Affinity Nucleosome Positioning Signal IsCapable of Transiently Positioning a Nucleosome In VivoLia E. Gracey, Zhi-Ying Chen, Jay M. Maniar, Anton Valouev, Arend Sidow, Andrew Z.Fire, Mark A. Kay.15 3:30 PMHyperactive piggyBac-Mediated Gene Transfer in Somatic Cells InVivoJoseph E. Doherty, Liqin Zhou, Kosuke Yusa, Allan Bradley, Nancy L. Craig, Matthew H.Wilson.16 3:45 PMHoming Endonucleases for Gene TherapyAdi Barzel, Hilla Giladi, Einat Sachar, Ludmila Rivkin, Eyal Privman, Mor Paldor, TalPupko, Toni Cathomen, Eithan Galun, Martin Kupiec.EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 87Abstract DirectoryThursday, May 20, 2010Oral Abstract Session 232Neurologic & Ophthalmic Gene & Cell Therapy2:00 PM - 4:00 PMRoom: Wilson ABC17 2:00 PMAAV-Mediated Gene Therapy Restores Visual Function and Behaviorto a Mouse Model of Leber Congential Amaurosis-1 (LCA1)Shannon E. Boye, Sanford L. Boye, Jijing Pang, Renee C. Ryals, Andy W. Neeley, DrewEverhart, Yumiko Umino, Joseph C. Besharse, Robert Barlow, William W. Hauswirth.18 2:15 PMAdeno-Associated Virus Vector Expressing an Amyloid beta 1-42Intrabody Rescues White Matter Pathology during Early Alzheimer’sDiseaseMaya K. Desai, Michael A. Mastrangelo, Deborah A. Ryan, Kelly L. Sudol, Wade C.Narrow, William J. Bowers.19 2:30 PMBrain Gene Therapy for Metachromatic Leucodystrophy: TowardsClinical TrialCaroline Sevin, Dolan Sondhi, Françoise Piguet, Marie-Anne Colle, Sylvie Raoul, ThomasRoujeau, Monique Piraud, Ornella Ahouansou, Celine Bouquet, Marie-Thérèse Vanier,Philippe Moullier, Yan Cherel, Neil R. Hackett, Michel Zerah, Patrick Aubourg, Ronald G.Crystal, Nathalie Cartier.20 2:45 PMNeonatal Intracerebroventricular Infusion of AAV2/8 Vector Leadsto High Levels of Human a-L-Iduronidase Expression in the Brainand Complete Neurophenotypic Correction in a Murine Model ofMucopolysaccharidosis Type IDaniel A. Wolf, Andrew W. Lenander, Zhenhong Nan, Lalitha R. Belur, Debra Swanson,Chester B. Whitley, Walter C. Low, R. Scott McIvor.21 3:00 PMCircuit-Specific Expression of Channelrhodopsin Restores VisualFunction in Blind rd1, rd16, and rho -/- MiceAlan Horsager, Jian Wen Liu, Edward S. Boyden, A. Cyrus Arman, Kimberly A. Silka,Mehdi Doroudchi, Shannon E. Boye, Benjamin C. Matteo, Alapakkam P. Sampath,William W. Hauswirth.22 3:15 PMCombination Therapy for the Treatment of Infantile Neuronal CeroidLipofuscinosis (INCL)Shannon L. Macauley-Rambach, Marie S. Roberts, Mark S. Sands.23 3:30 PMrAAV Delivery of a-Synuclein-Specific Single Chain AntibodiesAttenuates Dopamine Loss in a Mouse Model of Parkinson’s DiseaseKathleen Maguire-Zeuss, William J. Bowers, Wade Narrow, Eric Yehling, Howard J.Federoff.24 3:45 PMPatterns of Motor Function Recovery in a Murine Model of SevereMenkes Disease Rescued by Brain-Directed AAV5 Gene Therapy PlusCopperAnthony Donsante, Stephen G. Kaler.Oral Abstract Session 233Cancer – Immunotherapy T Cell Studies2:00 PM - 4:00 PMRoom: Thurgood Marshall W25 2:00 PMAdoptive Transfer of Peripheral Blood Lymphocytes GeneticallyModified To Express a T Cell Receptor Recognizing CarcinoembryonicAntigen into Patients with Metastatic Colorectal Cancer InducedInflammatory Colitis without Mediating Anti-Tumor EffectsMaria R. Parkhurst, James C. Yang, Russell C. Langan, Steven A. Feldman, Mark E.Dudley, Paul F. Robbins, Steven A. Rosenberg.26 2:15 PMAdenovirus Mediated Expression of Flt3L and HSV1-TK within theBrain Tumor Microenvironment Elicits Higher Therapeutic EfficacyThan Dendritic Cells’ VaccinationYohei Mineharu, Gwendalyn D. King, Marianela Candolfi, Weidong Xiong, Hikmat Assi,Kader Yagiz, Kurt M. Kroeger, Patricia Lin, B. Serguei, Pedro R. Lowenstein, Maria G.Castro.27 2:30 PMPharmacokinetics of Anti-PSMA Gene-Modified T Cells Infused afterNon-Myeloablative Conditioning in Prostate CancerAnthony J. Bais, Qiangzhong Ma, Hannah Boss, Esther L. Beaudoin, Richard P. Junghans.28 2:45 PMBinary Control of Tumor-Specific Cytotoxic T Lymphocytes byTransgenic IL7 and IL7r ExpressionJuan F. Vera, Ceidy Sanchez, Sujatha Muralidharan, Helen E. Heslop, Cliona M. Rooney,Gianpietro Dotti, Malcolm K. Brenner.29 3:00 PMMulti-Tumor-Antigen-Specific Cytotoxic T Lymphocytes for CancerImmunotherapyUlrike Gerdemann, Juan F. Vera, Anne S. Christin, Russell C. Cruz, Helen E. Heslop,Malcolm K. Brenner, Catherine M. Bollard, Cliona M. Rooney, Ann M. Leen.30 3:15 PMSimultaneous Comparison of T Cells Expressing 1 st or 2 nd GenerationCARs in Human Subjects with B-Cell Malignancies: Contribution ofCostimulatory EndodomainsB. Savoldo, C. Ramos, C. Bollard, E. Liu, M. Mims, M. Keating, A. Gee, Z. Mei, C.Rooney, H. Heslop, M. Brenner, G. Dotti.Thursday, May 20 th

88American Society of Gene & Cell TherapyAbstract DirectoryThursday, May 20 thThursday, May 20, 2010Oral Abstract Session 233 — continuedCancer – Immunotherapy T Cell Studies2:00 PM - 4:00 PMRoom: Thurgood Marshall W31 3:30 PMProlonged Regression of Lymphoma and Elimination of CD19 + Cellsin a Patient That Received Anti-CD19 Chimeric Antigen Receptor-Transduced T CellsJ. N. Kochenderfer, M. E. Dudley, R. A. Morgan, I. Maric, M. Raffeld, M. Stetler-Stevenson, J. E. Janik, W. H. Wilson, C. M. Yuan, S. A. Rosenberg.32 3:45 PMMarked Regression of Adenopathy Following Infusion of AutologousT Cells Genetically Targeted to the CD19 Antigen in a Patient withBulky CLLRenier J. Brentjens, Isabelle Riviere, Mark Frattini, Xiuyan Wang, Clare Taylor, MalgorzataOlszewska, Oriana Borquez-Ojeda, Shirley Bartido, Jolanta Stefanski, Raymond Yeh,Michel Sadelain.37 3:00 PMInsect Cell Carriers for Systemic Delivery of Oncolytic VirusesDominic G. Roy, Anthony T. Power, Fabrice Le Boeuf, John C. Bell.38 3:15 PMClinical Translational Development of rVSV(MD51)-M3:Biodistribution and Pharm/Tox Studies in Rats and MonkeysMarcia Meseck, Nelson Humala, Boxun Xie, Swan Thung, Susan Morgello, GreggGoldschlager, Savio Woo.39 3:30 PMA High-Throughput Pharmaco-Viral Approach Identifies OncolyticNovel Virus SensitizersJean-Simon Diallo, Fabrice Le Boeuf, Frances Lai, Julie Cox, Markus Vaha-Koskela,Hesham Abdelbary, Heather MacTavish, Katherine Waite, Theresa Falls, Jenny Wang,Ryan Brown, Jan E. Blanchard, Eric D. Brown, David H. Kirn, John Hiscott, Harry Atkins,Brian D. Lichty, John C. Bell.40 3:45 PMIdentification of Adenovirus Modulator Genes in Human Cancer Cellsby Whole Genome RNAi Library ScreeningChristie Vermeulen, Nikki Tol, Ida van der Meulen-Muileman, Winald R. Gerritsen, VictorW. van Beusechem.Oral Abstract Session 234Cancer-Oncolytic Viruses I2:00 PM - 4:00 PMRoom: Marriott Ballroom Salon 133 2:00 PMDemonstration of Delivery and Antitumoral Activity of JX-594, aTargeted Multi-Mechanistic Oncolytic Poxvirus, Following a SingleIntravenous Infusion in Patients with Refractory Metastatic CancersJames Burke, Joe Stephenson, Laura Chow, Derek Jonker, Andrew Haas, Jorge Nieva,Kara Sabourin, Adina Pelusio, Caroline Breitbach, Taeho Hwang, Anne Moon, KelleyParato, Manijeh Daneshmand, John C. Bell, David H. Kirn.34 2:15 PMHighly Attenuated Vaccinia Virus with microRNA-Regulated Oncolysisfor Cancer VirotherapyMina Hikichi, Minoru Kidokoro, Hisatoshi Shida, Hideaki Tahara, Takafumi Nakamura.35 2:30 PMA Phase 1 Trial of Intravesical (IVE) CG0070 in Patients withSuperficial Bladder Cancer after BCG FailureJames M. Burke, Don Lamm, James Mckiernan, John Nemunaitis, Joe Stephenson, MaxMeng, James Arsenau, Junko Aimi, Daniel Maslyar.36 2:45 PMA Phase 1 Trial of the Novel Infectivity-Enhanced BicistronicAdenovirus Ad5.SSTR/TK.RGD in Recurrent Gynecologic CancerKenneth H. Kim, Kellie Schneider, Minghui Wang, Janis O’Malley, Wen Wan, MeredithA. Preuss, Raymond D. Harris, Rosemarie Aurigemma, Gene P. Siegal, Kurt Zinn, DavidT. Curiel, Ronald D. Alvarez.Oral Abstract Session 235Immunologic & Host Responses in Gene & Cell Therapy2:00 PM - 4:00 PMRoom: Virginia Suite41 2:00 PMRepeated Autologous Infusions of Cells Modified with VSV-G-Pseudotyped Lentiviral Vector VRX496 Can Induce Anti-VSV-GHumoral Response in Humans without Clinical Consequence or Effecton Modified Cells Persistence: Findings from Lexgenleucel-T Phase 2Clinical TrialFranck Lemiale, Lindsay Shovlin, Kris Andre, Gerard McGarrity, Tessio Rebello, LaurentHumeau.42 2:15 PMIntensive Pharmacological Immunosuppression Allows for RepetitiveLiver Gene Transfer with Recombinant Adenovirus in NonhumanPrimatesAntonio Fontanellas, Sandra Hervás-Stubbs, Itsaso Mauleón, Juan Dubrot, UxuaMancheño, María Collantes, Ana Sampedro, Carmen Unzu, Carlos Alfaro, Asis Palazón,Rafael Enríquez de Salamanca, Cristian Smerdou, Alberto Benito, Jesús Prieto, IvánPeñuelas, Ignacio Melero.43 2:30 PMInduction of Regulatory T Cells as an Approach To Modulate CTLResponses Against AAV Capsid EpitopesDaniel J. Hui, Gary Pien, Etiena Basner-Tschakarjan, Federico Mingozzi, Jonathan D.Finn, Shangzhen Zhou, William Martin, Anne S. De Groot, Katherine A. High.EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 89Abstract DirectoryThursday, May 20, 2010Oral Abstract Session 235 — continuedImmunologic & Host Responses in Gene & Cell Therapy2:00 PM - 4:00 PMRoom: Virginia Suite44 2:45 PMLong-Term Phenotypic Correction of Hemophilia A after NeonatalAdministration of AAVChuhong Hu, Fides D. Lay, Joseph Springer, Ronald W. Busuttil, Gerald S. Lipshutz.45 3:00 PMImpact of Pre-Existing Neutralizing Antibodies on AAV8-Mediated,Liver-Directed Gene Transfer and Vector Biodistribution in NonhumanPrimatesLili Wang, Roberto Calcedo, Peter L. Bell, Martin W. Lock, Rebecca L. Grant, James M.Wilson.46 3:15 PMAutologous Dendritic Cell Therapy for Tolerance InductionGautam Sule, Masataka Suzuki, Racel Cela, John Rodgers, Brendan Lee.47 3:30 PMDifferential Transgene Expression in Dendritic Cells with UniqueRegulatory Cassettes Impacts Efficacy in Pompe DiseaseBaodong Sun, Ping Zhang, Xiao Yi Yang, Timothy C. Clay, Dwight D. Koeberl.48 3:45 PMImpact of the Host Environment on the Control of Gene Transfer-Induced Immune Responses with miRNA142.3p-Regulated VectorsFlorence Boisgérault, David-Alexandre Gross, Maxime Ferrand, Sylvie Darocha, JérômePoupiot, Marc Bartoli, Isabelle Richard, Anne Galy.Oral Abstract Session 236Oligonucleotide & RNAi Therapeutics I2:00 PM - 4:00 PMRoom: Delaware Suite49 2:00 PMSystemic Delivery of Antisense Morpholino Corrects RNA Mis-Splicing and Reduces Myotonia in a Transgenic Mouse Model ofMyotonic Dystrophy Type 1Thurman M. Wheeler, Yong-Fu Li, Krzysztof Sobczak, Paul A. Morcos, Charles A.Thornton.50 2:15 PMTriplex-Induced Correction of IDUA Gene Mutations as a Novel HurlerSyndrome TherapyJake del Campo, Karla D’Agostino, Ranjit S. Bindra, Peter M. Glazer.51 2:30 PMUsing rAAV Delivered miRNAs To Knockdown Misfolded HumanAlpha 1 Antitrypsin in a Transgenic Mouse ModelChristian Mueller, Qiushi Tang, Bryan O’Sullivan Murphy, Terence R. Flotte.52 2:45 PMConstitutive Long-Term Expression of shRNA in Liver Induces CellularStressMiwon Ahn, Scott R. Witting, Rafaela Ruiz, Romil Saxena, Nuria Morral.53 3:00 PMIn Vivo AAV Delivered Allele Specific shRNA for the Knockdown ofAlpha-1 AntitrypsinChristian Mueller, Bryan O’Sullivan-Murphy, Qiushi Tang, Terence R. Flotte.54 3:15 PMExpression Determinants of Mammalian Argonaute Proteins inMediating Gene SilencingPaul N. Valdmanis, Shuo Gu, Praveen Sethupathy, Mark A. Kay.55 3:30 PMAntisense Oligonucleotide-Mediated Therapy Increases SMN Levelsin the CNS and Prolongs Survival in a Severe Mouse Model of SpinalMuscular AtrophyMarco A. Passini, Jie Bu, Amy M. Richards, Lisa M. Stanek, S. P. Sardi, Yimin Hua, GeneHung, Lamya S. Shihabuddin, C. F. Bennett, Adrian R. Krainer, Seng H. Cheng.56 3:45 PMMultiple Exon-Skipping Using Cell-Penetrating Morpholinos forDystrophic DogsToshifumi Yokota, Takashi Saito, Nobuyuki Urasawa, Tetsuya Nagata, Akinori Nakamura,Ryszard Kole, Peter Sazani, Terence Partridge, Shin’ichi Takeda, Eric Hoffman.Poster Session I6:15 PM - 8:15 PMRoom: Exhibit Hall C & B-SouthAAV Vectors I57Enveloped AAV Vectors for Gene Transfer ApplicationsCasey A. Maguire, Lucia Mincheva-Nilsson, Vladimir Baranov, Bakhos A. Tannous, MiguelSena-Esteves, Xandra O. Breakefield, Johan Skog.58Chimpanzee-Derived Novel Natural Variants of AAV9: VectorDevelopment and Interrogation of Correlations between CapsidStructure and Vector BiologyLi Zhong, Jun Xie, Qing Xie, Kim Van Vliet, Qiang Wang, Mengxin Li, Qin Su, Ran He,Jason Goetzmann, Mavis Mckenna, Terry Flotte, Guangping Gao.59Gene Delivery to the Pig Cone-Enriched Retina Highlights Species-Specific Differences in AAV-Mediated Photoreceptor TransductionClaudio Mussolino, Francesco Viola, Michele Della Corte, Settimio Rossi, Umberto DiVicino, Simona Neglia, Monica Doria, Francesco Testa, Roberto Giovannoni, ManuelaCrasta, Massimo Giunti, Edoardo Villani, Marialuisa Lavitrano, Maria Laura Bacci,Roberto Ratiglia, Francesca Simonelli, Alberto Auricchio, Enrico M. Surace.Thursday, May 20 th

90American Society of Gene & Cell TherapyAbstract DirectoryThursday, May 20 thThursday, May 20, 2010Poster Session I — continued6:15 PM - 8:15 PMRoom: Exhibit Hall C & B-SouthAAV Vectors I60Enhancing AAV2 Transduction by Anti-Microtubule Drugs throughRhoA GTPase ActivationPing-Jie Xiao, Richard J. Samulski.61Tyrosine Mutations in the Capsid of AAV Vectors Alters TransductionProperties in the RetinaHilda Petrs-Silva, Astra Dinculescu, Seok H. Min, Li Zhong, Sergei Zolotukhin, ArunSrivastava, Alfred Lewin, William W. Hauswirth.62Riding Along with AAV: Mechanistic Studies on Vesicular TraffickingPathways of AAV SerotypesShen Shen, Xin Ming, Aravind Asokan, Rudy L. Juliano.63Effects of DNA Methylation on AAV Integration and TransgeneExpressionDiptiman Chanda, Jonathan A. Hensel, Jerome T. Higgs, Niroop Kaza, Rajat Grover,Selvarangan Ponnazhagan.64Efficient Transduction of Mouse Liver and Other Organs FollowingIntravenous Administration of a Recombinant Porcine AAVAlexander J. Bello, Allan R. Chand, Monica Doria, Kaylie Tran, Mariacarmela Allocca,Alberto Auricchio, Gary Kobinger.65Rational Design Meets Directed Evolution for Tailoring the AAVCapsidLuk H. Vandenberghe, Ru Xiao, Christie L. Bell, Kim Van Vliet, Jing Lu, Mavis Agbandje-McKenna, James M. Wilson.66AAV5 Transduction and Transgene Expression and Bioactivity inFibroblast-Like Synoviocytes from Rheumatoid Arthritis PatientsCaroline J. Aalbers, Scott A. Loiler, Federico Mingozzi, Paul-Peter Tak, Margriet J.Vervoordeldonk.67Pre-Injection of Polymers Can Increase the In Vivo TransductionEfficiency of Adeno-Associated Virus Type 2Gilles Moulay, Sylvie Boutin, Carole Masurier, Daniel Scherman, Antoine Kichler.68Therapeutic Expression of FIX at Reduced Doses Using AAV-ProteinPhosphotase-5 Helper VirusBrandon K. Sack, Jayandharan R. Giridhara, Zhong Li, Herzog W. Roland, SrivastavaArun.69A Scalable Process for Purification of Recombinant Adeno-AssociatedVirus Serotype 9Jingmin Zhou, Xiao Yang, Linda Couto, Katherine A. High, Guang Qu.70Adeno- Associated Virus Type 2 Rep Proteins Mediate PreferentialIntegration of a Lentiviral VectorVictor J. McAlister, Tshaka Cunningham, Anthony T. Craig, Roland A. Owens.71High Throughput Assay for Quantifying In Vitro AAV VectorTransduction Efficiency in ARPE19 CellsRenee C. Ryals, Sanford L. Boye, Shannon Boye, Andrew Neely, William W. Hauswirth.72Optimization of Parameters for AAV Production in Insect Cells andConditions for Baculovirus StorageHaifeng Chen.Adenovirus and Other DNA Virus Vectors I73Radiation-Induced Liver Fibrosis Is Mitigated by Gene TherapyAgainst Transforming Growth Factor-b Signaling in the RatDu Shi-Suo, Zeng Zhao-Chong, Zhou Jian, Tan Yun-shan, Zhang Zheng-Yu, Zeng Hai-Ying,Liu Zhong-shan.74Protection of Salivary Glands from Irradiation Damage by hMnSODGene TransferAna P. Cotrim, Anne M. Rowzee, A. Sowers, James B. Mitchell, Bruce J. Baum.75Intrathecal Injection of HDAd Vectors Results in Long-Term TransgeneExpression in Neuroepithelial Cells and NeuronsPasquale Piccolo, Scott Dindot, Nathan Grove, Donna Palmer, Nicola Brunetti-Pierri.76Virion-Associated Co-Factor HMGB1 Facilitates Transposition fromthe HSV/Sleeping Beauty Amplicon Vector PlatformSuresh de Silva, Louis T. Lotta, Clark A. Burris, William J. Bowers.77hKGF Gene Transfer for the Prevention of Radiation-Induced SalivaryHypofunctionChangyu Zheng, Ana P. Cotrim, Anne M. Rowzee, William D. Swaim, Anastasia Sowers,James B. Mitchell, Bruce J. Baum.78Generation of Replication-Defective Adenovirus Vector ExpressingHCV Structural Gene CE1E2 and Comparative Immunogenicity in Micewith Different Delivery RoutesJie Guan, Yao Deng, Xiao Yin, Wenjie Tan, Xiaobing Wu.EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 91Abstract DirectoryThursday, May 20, 2010Poster Session I — continued6:15 PM - 8:15 PMRoom: Exhibit Hall C & B-SouthAdenovirus and Other DNA Virus Vectors I79Interaction between Adenoviral Vector-Transduced Dendritic Cell-Based Cancer Vaccine and T Regulatory or T Helper 17 CellsAdele Y. Wang, Sarah Q. Crome, Kristy M. Jenkins, Jeffrey A. Medin, Jonathan L.Bramson, Megan K. Levings.80Replicating Adenoviruses That Harbors the ADP Protein and theSodium Iodide Symporter Protein (NIS) under the Control of theMajor Late Adenovirus PromoterMiguel A. Trujillo, Julia Davydova, Michael J. Oneal, Samantha McDonough, MasatoYamamoto, John C. Morris.81FX Domain Fused to Single-Chain Antibodies Improve Oncolytic Effectof Ad5 In Vitro and In VivoChristopher Y. Chen, Michael A. Barry.82Sustained Inhibition of Hepatitis B Virus Replication In Vivo UsingHelper-Dependent Adenovirus VectorsCarol Crowther, Betty Mowa, Felix Salazar, Patricia Marion, Abdullah Ely, PatrickArbuthnot.83Adenovirus Serotype 5/35 Is Excellent for Genetic Engineering ofTumor-Directed T CellsHannah Karlsson, Camilla Lindqvist, Bengt Simonsson, Ulla Olsson-Strömberg, AngelicaS. I. Loskog.84Bipartite Adenoviral Vector Encoding hHGF and hXIAP for ImprovedHuman Islet TransplantationHao Wu, A-Rum Yoon, Chae-Ok Yun, Ram I. Mahato.85Vector Prime-Protein Boost Vaccine for Patients with TherapyInduced LymphopeniaTae Hee Han, Yucheng Tang, Yeon Hee Park, Pingchuan Li, Hakan Akbulut, Line Petersen,Jonathan Maynard, Albert Deisseroth.86The Effect of Surface Modification of Adenovirus with an Arginine-Grafted Bioreducible Polymer on Transduction Efficiency andImmunogenicity in Cancer Gene TherapyPyung-Hwan Kim, Tae-il Kim, James W. Yockman, Sung Wan Kim, Chae-Ok Yun.Targeting Gene Modification and Integration87Safe and Efficient Delivery of Meganucleases for Lentivirus-MediatedGene TargetingAraksya Izmiryan, Alix Bourdel, Arnaud Jollet, Frédéric Pâques, Olivier Danos.88Site-Specific Genome Modification of Human Primary T LymphocytesTo Improve the Safety and Efficacy of Adoptive ImmunotherapyPietro Genovese, Elena Provasi, Angelo Lombardo, Zulma Magnani, Andreas Reik, Pei-QiLiu, Oscar Muniz Pello, Jurgen Kuball, Philip D. Gregory, Michael C. Holmes, Philip D.Greenberg, Chiara Bonini, Luigi Naldini.89Single-Strand Nicks Induce Homologous Recombination with LessToxicity Than Double-Strand Breaks Using an AAV TemplateMichael J. Metzger, Audrey McConnell-Smith, Barry L. Stoddard, A. Dusty Miller.90Targeted Gene Insertion in Human Chromosomes Using a HomingEndonucleaseByoung Y. Ryu, Michael T. Certo, Mikhail Garibov, Andrew M. Scharenberg, David J.Rawlings.91Cell Synchronization by Serum Shock Facilitates rAAV-Mediated GeneTargetingYonglun Luo, Emil Kofod-Olsen, Jenny Blechingberg, Rikke Christensen, Nicklas HeineStaunstrup, Lars Bolund, Charlotte Brandt Sørensen.92Critical Amino Acid Residues within the PhiC31 Integrase DNABinding Domain Affect Recombination Activities in Mammalian CellsRaphael Liesner, Wenli Zhang, Nadja Noske, Anja Ehrhardt.93Chromatin Structure of Two Genomic Sites for Targeted TransgeneIntegration in Induced Pluripotent Stem CellsRuan van Rensburg, Oleg Denisenko, Karol Bomsztyk, Andre Lieber.94Targeted Plasmid Integration into the PiggyBac Transposon by anEngineered Zinc Finger RecombinaseCharles A. Gersbach, Russell M. Gordley, Thom Gaj, Andrew C. Mercer, Carlos F. Barbas,III.95Development of Autonomously Working Zinc-Finger Nuclease Pairsfor Targeted Genome EngineeringCem Söllü, Kaweh Montazami-Astaneh, Morgan L. Maeder, Stacey Thibodeau-Beganny,J. Keith Joung, Toni Cathomen.96Adeno-Associated Virus-2 (AVV2) Integrase Mediates SpecificIntegration to Locus AAVS1 on Chromosome 19q13.3 in aHematopoietic Cell LineAshley E. Dunfee, Joshua R. Clevenger, Cynthia E. Dunbar, Andre Larochelle.Thursday, May 20 th

92American Society of Gene & Cell TherapyAbstract DirectoryThursday, May 20 thThursday, May 20, 2010Poster Session I — continued6:15 PM - 8:15 PMRoom: Exhibit Hall C & B-SouthTargeting Gene Modification and Integration97Gene Correction in Mouse LiverHiroyuki Kamiya, Masayuki Uchiyama, Jingshu Piao, Yoshimichi Nakatsu, TeruhisaTsuzuki, Hideyoshi Harashima.98A Transient Cold Shock Enhances Zinc-Finger Nuclease-Mediated GeneDisruptionYannick Doyon, Vivian M. Choi, Danny Xia, Thuy D. Vo, Michael C. Holmes, Philip D.Gregory.99Single-Polarity rAAV May Enhance Hepatic Gene Targeting In VivoNicole K. Paulk, Markus Grompe.Physical Methods of Delivery100Over-Expression of Adiponectin and Adiponectin Receptor 2 Gene bythe Method of Hydrodynamic Gene Delivery Prevents Weight Gainand Development of Insulin Resistance in AKR/J MiceYongjie Ma, Dexi Liu.101Duration of Expression after Gene Electrotransfer to Skin Depends onthe Gene of InterestAnita Gothelf, Jens Eriksen, Pernille Hojman, Julie Gehl.102Intravenous Delivery of pDNA and siRNA into Muscle by Ultrasound-Mediated Bubble LiposomesYoichi Negishi, Yoko E. Takahashi, Yuko Ishii, Ryo Suzuki, Kazuo Maruyama, YukihikoAramaki.103Prototype Development and Pre-Clinical Immunogenicity Analysis ofa Novel Minimally Invasive Electroporation DeviceKate E. Broderick, Jay McCoy, Xuefei Shen, Feng Lin, Amir Khan, Matthew Morrow,Stephen Kemmerrer, David B. Weiner, Niranjan Y. Sardesai.104Ultrasound-Assisted Non-Viral Gene Transfer to the Salivary GlandsMichael J. Passineau, Lee Zourelias, Laurie Machen, Paul C. Edwards, Raymond L. Benza.105Development of Electroporation Formulation for Cell TherapyMike Flanagan, Gang Yu, Jeffry Gimble, Shulin Li.106Ca 2+ Electrotransfer; a Quick Stop Procedure Against TransgenicExpressionPernille Hojman, Iben Spanggaard, Julie Gehl, Hanne Gissel.107In Vivo Gene Delivery to the Skin by Electroporation Using a MultipleElectrode ArraySiqi Guo, Amy Donate, Gaurav Basu, Kathryn Lundberg, Richard Heller.108Hydrodynamic Gene Delivery Efficiency Is Reduced in Fibrotic Liver inRatsTian Zhou, Dexi Liu.109Efficiency of Electroporation Delivery of Peptide Nucleic Acid (PNA)Depends on PNA Charge and Electrotransfer ProtocolMette Joergensen, Birgit Agerholm-Larsen, Peter E. Nielsen, Julie Gehl.110Biodistribution of Plasmid AMEP, a Potent Antitumor Gene Productfor the Treatment of Metastatic MelanomasCeline Bouquet, Elisabeth Dam, Veronique Trochon-Joseph, Valerie Polard, VincentSainte-Catherine, Emilienne Soma, Sophie Lebel-Binay.111In Vivo Intracellular Injection Needle (IvIn) Technology: A NewNeedle for Improved Cellular Uptake of DNA in a Live AnimalLars Frelin, Gustaf Ahlén, Matti Sällberg.112A Study on Techniques for Safety Assessment of Gene TherapyProducts Using ElectroporationMin Joung Choi, Il Ung Oh, Sung Yeol Han, Oh Seok Kwon, Seung Hwa Hong.113Toxicology and Safety Studies of Plasmid AMEP, a New EfficientAntitumor Gene Product for the Treatment of Metastatic MelanomasCeline Bouquet, Veronique Trochon-Joseph, Valerie Polard, Vincent Sainte-Catherine,Emilienne Soma, Sophie Lebel-Binay.114Enhancement of the Immune Response of a Noval DNA VaccineEncoding Conserved NS3 and Core Fusion Gene of HCV Injected byIntradermal Electrotransfer in MiceXiao Yin, Jian Lu, Wenjie Tan, Jie Guan, Li Ruan.115Electroporation-Enhanced DNA Prime/Protein Boost Strategy ToImprove Cross-Clade Immunogenicity of HIV-1 Envelope AntigenKate E. Broderick, K. Muthumani, Xuefei Shen, Jian Yan, Feng Lin, Janess Mendoza,Amir Khan, Niranjan Y. Sardesai, David B. Weiner.116Effectiveness of Impedance Spectroscopy To Monitor Impact of anElectroporation Protocol on TissueJ. Anthony Llewellyn, Loree Heller, Richard A. Gilbert.EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 93Abstract DirectoryThursday, May 20, 2010Poster Session I — continued6:15 PM - 8:15 PMRoom: Exhibit Hall C & B-SouthChemical and Molecular Conjugates I117Modular Ternary Polyacridine DNA Polyplexes for Targeted GeneDeliveryNicholas J. Baumhover, Christian A. Fernandez, Sanjib Khargharia, Kevin G. Rice.118Biodegradable Polyamino Acid-Based Polycations for Safe andEffective Gene Transfer Minimizing Cumulative ToxicityKeiji Itaka, Takehiko Ishii, Kazunori Kataoka.119Interplay of Clathrin and Caveolin Trafficking Pathways in Polymer-Based Gene DeliveryMark E. Hwang, Rahul K. Keswani, Daniel W. Pack.120Folate Linked Targeting Systems Increase Transfection Efficiency andSpecificity in Human Epithelial CellsNathalie Carmoy, Emmanuel Mornet, Céline Lainé, Loic Lemiegre, Tony Le Gall, DanielleGillet, Mattias Lindberg, Rémi Marianowski, Pierre Lehn, Thierry Benvegnu, TristanMontier.121In Vivo Gene Delivery from Modified PLG ScaffoldsMisael O. Aviles, Lonnie D. Shea.122The Influence of Charge Density and Substituent Composition onImidazolium-Containing Polymers for Mediated DNA DeliveryMichael H. Allen, Matthew D. Green, Timothy E. Long.123Concentrated PEI Formulations Retain Biological Efficacy FollowingLong-Term Storage at 4°CLee A. Davies, Graciela A. Nunez-Alonso, Stephen C. Hyde, Deborah R. Gill.124Charge Density and Molecular Weight of Polymeric Gene CarrierAre Key Parameters Influencing Its DNA Compaction Ability andTransfection EfficiencyYong Ren, Xuan Jiang, Hai-Quan Mao.125Designing Imidazole-Containing Polymeric Vectors with ControlledCharge Densities for Gene DeliveryMatthew D. Green, John M. Layman, Alec S. Good, Sean M. Ramirez, Lulit A. Affin,Michael H. Allen, Timothy E. Long.126Bioreducible Poly(amido ethyleneimine) and Its PolyethyleneGlycol Graft Copolymer Analog Formulations Offer Ease of Use inOptimizing Improved Nucleic Acid DeliveryJames W. Yockman, Jonathan H. Brumbach, Young Won Lee, Chao Lin, Johan F. J.Enbersen, Jan Feijen, Sung Wan Kim.127Role of Glycosaminoglycans in Peptide-Mediated DNA DeliveryRangeetha J. Naik, Pallavi Chandra, Anindo Chatterjee, Munia Ganguli.128Galactosylated-DPC Nanoparticles for Targeted Hepatic GeneDelivery In VivoKeun-Sik Kim, Yeon Kyung Lee, Jung Seok Kim, Jin Ee Back, Sang Il Park, Hwa YeonJeong, Young Eun Shin, Yong Serk Park.129Effect of Molecular Weight on Plasmid DNA Delivery Efficiency ofPalmitic Acid Substituted PolyethylenimineK. C. B. Remant, Breanne Landry, Hasan Uludag.130Electrospun Fibers with the Core-Loading of DNA andPoly(ethyleneimine) Complex as Potential Tissue Engineering ScaffoldYe Yang, Long Cheng, Shuhui He, Jie Zou, Fang Chen, Xiaohong Li.131A Novel Cationic Lipophosphoramide with Phytanyl Chains: Gain inTransfection Efficiency and Clinical Approach Concerning the Responseto LipofectionMattias Lindberg, Nathalie Carmoy, Christophe Lorilleux, Aurore Fraix, Tony Le Gall,Pierre Lehn, Paul-Alain Jaffrès, Tristan Montier.132Cationic Peptide-Based DNA Delivery In Vitro: The Role of DNACondensation and ReleaseAnita Mann, Garima Thakur, Vasundhara Shukla, Rangeetha Naik, Anand Kamal Singh,Richa Khanduri, Munia Ganguli.Genetic and Metabolic Diseases Gene & Cell Therapy I133Modeling and Correcting Fibrous Dysplasia with Lentiviral VectorsIsabella Saggio, Cristina Remoli, Stefania Cersosimo, Stefania Piersanti, Paolo Bianco,Mara Riminucci.134Bone Marrow Transplantation Cures Hemophilia AAntonia Follenzi, Sanj Raut, Simone Merlin, Rita Sarkar, Sanjeev Gupta.135Cell Autonomy in Methylmalonic Acidemia (MMA): Implications forGene and Cell TherapyIrini Manoli, Justin R. Sysol, Randy J. Chandler, Jennifer Sloan, Patricia Zerfas, VictoriaHoffmann, Mones Abu-Asab, Maria Tsokos, Charles P. Venditti.Thursday, May 20 th

94American Society of Gene & Cell TherapyAbstract DirectoryThursday, May 20 thThursday, May 20, 2010Poster Session I — continued6:15 PM - 8:15 PMRoom: Exhibit Hall C & B-SouthGenetic and Metabolic Diseases Gene & Cell Therapy I136Efficacious Gene Therapy in Pompe Disease Requires Mannose-6-Phosphate Receptor ExpressionBaodong Sun, Deeksha Bali, Y.-T. Chen, Dwight D. Koeberl.137Development of a Safe Hematopoietic Stem Cell (HSC) MobilizationStrategy for Gene Therapy of ThalassemiaEvangelia Yannaki, Thalia Papayannopoulou, Erica Jonlin, Ioannis Batsis, Pamela Becker,Fani Zervou, Angeliki Xagorari, Garyfalia Karponi, Varnavas Constantinou, AchillesAnagnostopoulos, Athanasios Fassas, George Stamatoyannopoulos.138Long Term Expression in Liver from scAAV Seems Derived fromIntegrated Vector GenomesPaula S. M. Miranda, Maude Flageul, Christine Kaeppel, Lysbeth ten Bloemendaal,Dominique Aubert, Nowrouzi Ali, Manfred Schmidt, Nicolas Ferry, Piter J. Bosma.139Human Amnion Epithelial (AE) Stem Cell Transplant Improves DiseasePhenotype and Survival in Mouse Models of Intermediate MapleSyrup Urine Disease (MSUD)K. J. Skvorak, K. Dorko, M. Hansel, F. Marongiu, V. Tahan, K. M. Gibson, Q. Sun, T.Bottiglieri, E. Arning, J. Davila, S. Strom.140Gene Therapy Approaches Combining the ImmunomodulatoryProperties of Liver and IGF-I To Prevent Type I DiabetesSabrina Tafuro, Xavier M. Anguela, Judith Agudo, Alba Casellas, David Callejas, MercèObach, Carles Roca, Albert Ruzo, Fàtima Bosch.141Hepatocyte Engineering and Genetic Modification Approaches ofHemophilia Hepatocytes within a Living MouseKazuo Ohashi, Kohei Tatsumi, Chise Tateno, Hiroyuki Nakai, Anja Ehrhardt, Rie Utoh,Katsutoshi Yoshizato, Teruo Okano.142Serotype Optimization of an AAV Vector for Gene Therapy in Canineand Murine Glycogen Storage Disease Type Ia (GSD-Ia)Xiaoyan Luo, Amanda K. Demaster, Songtao Li, Kyha Williams, Talmage T. Brown, DanielM. Kozink, Andrew Bird, Dwight D. Koeberl.143Systemic Delivery of Bioactive Glucagon-Like Peptide 1 FollowingAdenoviral Vector-Mediated Gene Transfer to Murine SubmandibularGlandsAntonis Voutetakis, Anne M. Rowzee, Ana P. Cotrim, Changyu Zheng, Trushar Rathod,Tulin Yanik, Y. P. Loh, Bruce J. Baum, Niamh X. Cawley.144A Non-Viral, GNE-Lipoplex Treatment to Correct Sialylation Defectsin Gne-Mutant (M712T) MiceTal Yardeni, Carla Ciccone, Shelley Hoogstraten-Miller, Daniel Darvish, Yair Anikster, PhilMaples, Chris Jay, William A. Gahl, John Nemunaitis, Marjan Huizing.145Lentivirally Induced Over-Expression in the Mouse Hypothalamus;a Study of the Effects of Melanin Stimulating Hormones (MSH) inObesity and DiabetesKim Eerola, Siru Virtanen, Eriika Savontaus, Mikko Savontaus.146Alternative Methods for Ex Vivo Gene Transfer to Primary Murine BCellBabak Moghimi, Ou Cao.147A Full Characterization of the CAG 140 Huntington’s Disease MouseModelAaron C. Rising, Eileen Denovan-Wright, Ron Mandel.Musculo-skeletal Gene & Cell Therapy I148Assessment of Pre-Clinical Safety of GMP Grade GNE-Lipoplexesafter Repeat Intravenous Injections in Balb/c MiceAnagha P. Phadke, Chris M. Jay, Phillip B. Maples, Neil Senzer, John Nemunaitis, AlexW. Tong.149Pre-Existing Antibodies to AAV8 Attenuates Micro-DystrophinExpression Following Targeted Vascular DeliveryLouise R. Rodino-Klapac, Chrystal Montgomery, William Bremer, Nancy Davis, KimberlyShontz, Vinod Malik, Katherine Campbell, Thomas J. Preston, Zarife Sahenk, K. ReedClark, Brian D. Coley, Christopher M. Walker, Jerry R. Mendell, Louis G. Chicoine.150AAV Microgene Transfer Reveals the Cellular Motif for Dystrophin-Mediated Sarcolemmal Neuronal Nitric Oxide Synthase (nNOS)LocalizationYi Lai, Yongping Yue, Dongsheng Duan.151Cell Therapeutic Approach to Duchenne Muscular Dystrophy UsingMyogenic Differentiation of Multipotent Mesenchymal Stromal CellsYuko N. Kasahara, Hiromi H. Kinoh, Hironori Okada, Jin-Hong Shin, Akiyo Nishiyama,Sachiko O. Hosoyama, Michiko W. Maeda, Akinori Nakamura, Takashi Okada, Shin’ichiTakeda.EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 95Abstract DirectoryThursday, May 20, 2010Poster Session I — continued6:15 PM - 8:15 PMRoom: Exhibit Hall C & B-SouthMusculo-skeletal Gene & Cell Therapy I152Splice Site Strength and Nonsense-Associated Exon Skipping in theDMD GeneKevin M. Flanigan, Diane M. Dunn, Jerry R. Mendell, Alan Pestronk, Julaine M. Florence,United Dystrophinopathy Project Consortium, Robert B. Weiss.153Long Term Antisense Treatment in Dystrophic Mouse Models forDuchenne Muscular DystrophyAnnemieke Aartsma-Rus, Christa L. de Winter, Hans A. Heemskerk, Judith C. vanDeutekom, Gert-Jan B. van Ommen.154Exon Exchange Approach To Repair Duchenne Dystrophin TranscriptsStéphanie Lorain, Cécile Peccate, Maëva Le Hir, Graziella Griffith, Thomas Voit, LuisGarcia.155Gentamicin Treatment of Duchenne Muscular Dystrophy Reinforcesthe Potential for Mutation Suppression TherapyVinod Malik, Louise R. Rodino-Klapac, Laurence Viollet, Cheryl Wall, Wendy King,Roula Al-Dahhak, Sarah Lewis, Christopher J. Shilling, Janaiah Kota, John Hayes, JohnD. Mahan, Katherine J. Campbell, Brenda Banwell, Majed Dasouki, Victoria Watts,Kumaraswamy Sivakumar, Ricardo Bien-Willner, Kevin M. Flanigan, Zarife Sahenk,Richard J. Barohn, Christopher M. Walker, Jerry R. Mendell.156Reverse Perfusion Affords Efficient Whole-Body Gene Transfer toMuscle in the Large AnimalFrederick Balzer, Jacqueline Farag, Alock Malik, Mihail Petrov, Andrew Mead, BenjaminKozyak, Kapil Gopal, Marilyn Mitchell, Connie Choi, Jessie Chen, David Low, CharlesYarnall, Charles Bridges, Hansell Stedman.157Manganese Superoxide Dismutase Plasmid/Liposome Complex(MnSOD-PL) and Mitochondrial Targeted Nitroxide JP4-039Ameliorate Irradiation-Induced Delay in Bone Wound HealingJean-Claude Rwigema, Abhay Gokhale, Michael Epperly, Julie Glowacki, Tracy Dixon, KenPatrene, G. David Roodman, Peter Wipf, Joel Greenberger.158Genetic Correction of Netherton Syndrome Keratinocyte Stem CellsWaseem Qasim, Katerina Semenova, Gill Talbot, John Harper, Adrian Thrasher, FernandoLarcher, Wei Di.159Adenoviral Human Vascular Endothelial Growth Factor-D GeneTransfer Causes Angiogenesis and Growth and Enlargement ofLymphatic Vessels in Ischemic Mouse Hind LimbsGalina Dragneva, Ivana Kholová, Svetlana Laidinen, Petra Korpisalo, Pasi Tuunanen,Nina Kaskenpää, Suvi Heinonen, Felicitas Yongabi, Anna Stefanska, Varpu Marjomäki,Olli Gröhn, Seppo Ylä-Herttuala.160Validation of Intravascular Administration of Adeno-AssociatedVvirus for Muscular Dystrophies in a Non-Human Primate ModelAravind Asokan, Julia Hegge, Joshua C. Grieger, Chengwen Li, Swati Yadav, Jade J.Samulski , Xiao Xiao, Juan Li, Jon Wolff, R. Jude Samulski, Scott W. J. McPhee.Infectious Diseases and Vaccines: Vaccine Related GeneTransfer Research161Suppression of Cocaine-Induced Hyperactivity in Mice Pre-Treatedwith an Adenovirus-Based Anti-Cocaine VaccineJonathan B. Rosenberg, Martin L. Hicks, Bishnu P. De, Stephen M. Kaminsky, Amira Y.Moreno, Kim D. Janda, Stefan Worgall, Ronald G. Crystal.162Translation of Electroporation-Mediated DNA Vaccine Delivery intoa Phase I Clinical Trial Evaluating an HIV DNA Vaccine in HealthyVolunteersClaire F. Evans, Sandhya Vasan, Karen E. Dolter, Arlene Hurley, Sarah J. Schlesinger,Drew Hannaman, David F. Gardiner, Daniel P. Dugin, Yaoxing Huang, Josephine Cox,Tony Tarragona, Len Dally, Carol Smith, Claudia Schmidt, Harriet Park, Jill Gilmour,Patricia Fast, Robert Bernard, David D. Ho.163Longterm Protective Immunity Against Lethal Pulmonary Challengewith the Pseudomonas aeruginosa Following Mucosal Administrationof AdC7-OprF Expressing the P. aeruginosa Protein OprFAnja Krause, Wen Zhu, Yaqin Xu, Ju Joh, Ronald G. Crystal, Stefen Worgall.164Characterization of Adenoviruses Shed from the Macaque Gut andEvaluation of Immune Responses to Adenoviruses in the Macaque inthe Context of Future Adenoviral Vaccine StudiesSoumitra Roy, Roberto Calcedo, C. Angelica Medina-Jaszek, Qiuyue Qin, JenniferMiliaresis, Surina Boyd, Diane G. Carnathan, Michael R. Betts, James M. Wilson.165A Lentiviral HIV Vaccine Candidate Elicits Long-Term Humoral andCellular HIV-Specific Immunity and Minimal Neutralizing ActivityBenyam Asefa, Delia Ye, Nikolay Korokhov, Laurent M. Humeau, Franck Lemiale.166Coexpressed RIG-I Agonist Enhances Humoral Immune Response toInfluenza DNA VaccineJeremy M. Luke, Clague P. Hodgson, James A. Williams.Thursday, May 20 th

96American Society of Gene & Cell TherapyAbstract DirectoryThursday, May 20 thThursday, May 20, 2010Poster Session I — continued6:15 PM - 8:15 PMRoom: Exhibit Hall C & B-SouthInfectious Diseases and Vaccines: Vaccine Related GeneTransfer Research167Genetically Engineered Bifidobacterium Displaying Salmonella-AntigenProtects Mice from Lethal Challenge of Salmonella Typhimurium in aMurine Typhoid Fever ModelToshiro Shirakawa, Sakura Yamamoto, Jun Wada, Takane Katayama, Takumi Jikimoto,Masakuni Nakamura, Shohiro Kinoshita, Kyung-Mi Lee, Masato Kawabata.168Signaling Lymphocytic Activation Molecule (SLAM, CD150)-BlindMeasles Virus Is Attenuated and Induces Strong Adaptive ImmuneResponses in Rhesus MonkeysVincent Leonard, Gregory Hodge, Jorge Reyes-del Valle, Michael McChesney, RobertoCattaneo.169Evaluation of Mismatched Immunity To Expand Cross-ProtectionAgainst Influenza VirusAmi Patel, Isabelle Meunier, Kaylie N. Tran, Anders Leung, Stephane Pillet, DarwynKobasa, Veronika von Messling, Gary P. Kobinger.170Immune Response Against Measles Virus Encoding Helicobacter pyloriNeutrophil-Activating Protein AntigenIanko D. Iankov, Iana Haralambieva, Evanthia Galanis.171Generation of Chimeric GB Virus B Clones Encoding the Hepatitis CVirus E1E2p7 and coreE1E2p7 toward the Infected Marmoset ModelsTingting Li, Lifang Shuai, Zixuan Chen, Anqi Wang, Wenjing Wang, Chengyao Li.172Characterization of Immune Response in Mice Induced byRecombinant Vaccinia Virus (Tiantan) Based Multivalent H5N1 AvianInfluenza VaccinesWen Wang, Yao Deng, Wenjie Tan, Hong Chen, Li Ruan, Yuelong Shu.173The Effects of the Calreticulin on the Immune Response Induced byDNA Vaccine Containing the Classical Swine Fever Virus E2 Gene inMouse ModelMing Kun Hsieh, Chia Chin You, Chienjin Huang.174Evaluation of the Multi-Electrode Array for Use in DNA VaccinationAgainst Bacillus anthracisAmy L. Donate, Richard Heller.Cancer – Immunotherapy I175Enhancing the Priming of Tumor Antigen Specific T Cell ResponsesUsing Oncolytic VirusesPhonphimon Wongthida, Rosa Diaz, Feorillo Galivo, Karen Kaluza, Jill Thompson,Timothy Kottke, Richard Vile.176AdCD40L Immunogene Therapy for Bladder Carcinoma – A Phase I/IIa TrialPer-Uno Malmstrom, Angelica S. I. Loskog, Camilla A. Lindqvist, Sara M. Mangsbo, MoaFransson, Alkwin Wanders, Truls Gardmark, Thomas H. Totterman.177Treatment of Refractory Cancer Patients with a Serotype 5/3Chimeric Oncolytic Adenovirus Expressing Granulocyte MacrophageColony-Stimulating Factor (GM-CSF): Virological, Immunological andClinical EndpointsAnniina Koski, Sari Pesonen, Vincenzo Cerullo, Sophie Escutenaire, Elina Haavisto, LottaKangasniemi, Pekka Simula, Timo Joensuu, Akseli Hemminki.178IL-15 Reduces Suppressive Effects of Regulatory T Cells (Tregs) onAntigen-Specific Cytotoxic T Lymphocytes (CTLs)S. Perna, B. De Angelis, D. Pagliara, L. Zhang, C. Rooney, H. Heslop, M. Brenner, G.Dotti, B. Savoldo.179PiggyBac Transposon Modified EBV Specific Human T Lymphocytesfor HER2-Positive Cellular Immunotherapy In VivoYozo Nakazawa, Nabil Ahmed, Vita Salsman, Ann Leen, Stephen Gottschalk, MatthewH. Wilson, Cliona M. Rooney.180Adenovirus-Mediated Intratumoral Expression of ImmunostimulatoryMolecules Together with Systemic Depletion of Regulatory T-CellsInduces Tumor-Destructive Immune Responses in Mouse ModelsYing Liu, Jonas Persson, Sebastian Tuve, Roma Yumul, ZongYi Li, Steve Roffler, AndreLieber.181Key Role of B Cell as Antigen Presenting Cells in the Anti-TumorImmunity Induced by a Combined Immune-Stimulatory/ConditionalCytotoxic Therapy for GlioblastomaMarianela Candolfi, Kader Yagiz, James F. Curtin, Hikmat Assi, Mia Wibowo, GabrielleAlzadeh, David Foulad, Kurt Kroeger, Anderson Alden, Chunyan Liu, Robert Dunn, PedroR. Lowenstein, Maria G. Castro.182Genetically Engineered Malignant Glioma-Specific T Cells Resistant toGlucocorticoidsSeogkyoung Kong, Richard P. Junghans, Prakash Sampath.183Adoptive Transfer of T Cells Genetically Targeted to the MUC16Antigen Eradicates Established Peritoneal Ovarian Tumors in SCID-Beige MiceAlena A. Chekmasova, Thapi D. Rao, David R. Spriggs, Renier J. Brentjens.EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 97Abstract DirectoryThursday, May 20, 2010Poster Session I — continued6:15 PM - 8:15 PMRoom: Exhibit Hall C & B-SouthCancer – Immunotherapy I184Adoptive Transfer of Autologous T Cells Targeted to Prostate SpecificMembrane Antigen (PSMA) for the Treatment of Castrate MetastaticProstate CancerOriana Borquez-Ojeda, Jolanta Stefanski, Xiuyan Wang, Jason Plotkin, Jinrong Qu,Luis Rodriguez, Elliot Servais, Kei Suzuki, Larrisa Shenker, Vladimir Ponomarev, SusanSlovin, Michel Sadelain, Isabelle Rivière.185A New Human-Derived Reporter Gene Suitable for Clinical PETImaging of T-Cell TraffickingYury Likar, Juan Zurita, Larissa Shenker, Maxim Moroz, Shangde Cai, Anton Neschadim,Jeffrey Medin, Hedvig Hricak, Michel Sadelain, Vladimir Ponomarev.186Inhibition of Mice Colon Tumor Growth by Il-15 Immunogene TherapyXianghui He, Weidong Li, Yifeng Wang, Linan Hou, Liwei Zhu.187Development of High-Performance HVJ-E for Cancer Immune TherapyKotaro Saga, Katsuto Tamai, Takehiko Yamazaki, Yasufumi Kaneda.188Combined Gene Therapy Using Adenovirus Expressing Interleukin-12,Granulocyte-Macrophage Colony-Stimulating Factor, and ThymidineKinase with Prodrug GanciclovirJi-seong Kim, Kyoung-ju Choi, Chae-Ok Yun.189Safety Data of MGN1601, a Tumor Vaccine, Made of Allogeneic,Transfected and Irradiated Tumor Cells in Combination with anImmunomodulator for the Treatment of Metastatic Renal CellCarcinomaManuel Schmidt, Baerbel Volz, Matthias Schroff, Kerstin Kapp, Christiane Kleuss, MarinaTschaika, Burghardt Wittig.190Development of an HLA-A*0201 Restricted T Cell Receptor ThatRecognizes Peptide Epitopes from MAGE-A3 and MAGE-A12 forTargeted Adoptive T Cell Immunotherapy of Multiple Cancer TypesNachimuthu Chinnasamy, Jennifer A. Wargo, Zhiya Yu, Timothy L. Frankel, John P. Riley,Maria R. Parkhurst, Steven A. Feldman, Nicholas P. Restifo, Paul F. Robbins, Steven A.Rosenberg, Richard A. Morgan.Cancer-Oncolytic Viruses I191 (Moved to Oral Abstract Session 413)A Comparative Study of Stem Cell-Based Cell Carrier Systems for theSystemic Delivery of an Oncolytic Adenovirus for Antiglioma TherapyMatthew A. Tayler, Atique U. Ahmed, Ilya V. Ulasov, Irina Y. Balyasnikova, Maciej S.Lesniak.192A Novel Coxsackievirus B Shows Remarkable Oncolytic CapacityAgainst Lung CancerShohei Miyamoto, Hiroyuki Inoue, Meiko Yamada, Xin Meng, Takafumi Nakamura,Yasuo Urata, Hiroyuki Shimizu, Kenzaburo Tani.193Preclinical and Clinical Data with a Fully Serotype 3 OncolyticAdenovirus Ad3-hTERT-E1A in the Treatment of Advanced SolidTumorsOtto Hemminki, Gerd Bauerschmitz, Silvio Hemmi, Sergio Lavilla-Alonso, Iulia Diaconu,Anna Kanerva, Vincenzo Cerullo, Minna Oksanen, Elina Haavisto, Timo Joensuu, SariPesonen, Akseli Hemminki.194Mechanism of Tumour Penetration by Oncolytic Viruses –Investigation in a 3 Dimensional In Vitro ModelC. A. Campion, C. Harty, G. C. O’Sullivan, J. K. Collins.195Mechanisms of Cyclophophamide Enhancing Anti-Tumor Effects ofOncolytic Vesicular Stomatitis Virus for Breast Cancer TreatmentHongxun Wang, Stephen Russell, Jian Qiao.196Clinical Characterization of the Adenovirus Death Protein-PotentiatedOncolytic Adenovirus VRX007Alex W. Tong, Anagha P. Phadke, Staci Horvath, William Wold, John Nemunaitis, NeilSenzer.197Safety and Immunological Effects of Corticosteroids in PatientsTreated with Oncolytic AdenovirusesMaria Rajecki, Mari Raki, Andreas Helminen, Sophie Escutenaire, Sari Pesonen, VincenzoCerullo, Timo Joensuu, Elina Haavisto, Laura Ahtiainen, Akseli Hemminki.198Effect of Decorin on Overcoming the Extracellular Matrix Barrier forOncolytic VirotherapyIl-Kyu Choi, Young-Sook Lee, Ji Young Yoo, A-Rum Yoon, Hye Jin Choi, Daniela G. Seidler,Chae-Ok Yun.199Chondroitinase ABC1 Mediated Enhancement of OV Spread andEfficacyNina Dmitrieva, Mariano Viapiano, Balveen Kaur.200Use of PET Imaging for In-Vivo Monitoring of Replication CompetentRetrovirus (RCR) Transduction of Malignant GliomasWeijun Wang, Hui Wang, Ryan Park, Hancheng Cai, Peter S. Conti, Nori Kasahara,Thomas C. Chen.Thursday, May 20 th

98American Society of Gene & Cell TherapyAbstract DirectoryThursday, May 20 thThursday, May 20, 2010Poster Session I — continued6:15 PM - 8:15 PMRoom: Exhibit Hall C & B-SouthCancer-Oncolytic Viruses I201Systemic Cancer Screening Using an Oncolytic HSV To Induce Tumor-Selective Expression of a Secretable Serum BiomarkerAndrew W. Browne, Jennifer L. Leddon, Mark A. Currier, Jon P. Williams, Nancy Ratner,Timothy P. Cripe.202Therapeutic and Tumor-Specific Immunity Induced by Combinationof Dendritic Cells and Oncolytic Adenovirus Expressing IL-12 and4-1BBLSong-Nan Zhang, Jing-Hua Huang, Joo-Hang Kim, Kyung-Ju Choi, Il-Kyu Choi, MingulLee, Chae-Ok Yun.203Oncolytic Herpes Simplex Virus Encoding Interferon b Gene forSquamous Cell Carcinoma of the Head and NeckHongtao Li, Stephen J. Russell.204Targeted Suicide Gene Therapy with Oncolytic AdenovirusCoding for FCU1, a Fusion Protein of Cytosine Deaminase andUracilphosphoribosyltransferaseJoão D. Dias, Ilkka Liikanen, Kilian Guse, Johann Foloppe, Marta Sloniecka, Iulia Diaconu,Ville Rantanen, Minna Eriksson, Tanja Hakkarainen, Monika Lusky, Philippe Erbs, SophieEscutenaire, Anna Kanerva, Sari Pesonen, Vincenzo Cerullo, Akseli Hemminki.Cancer-Targeted Gene & Cell Therapy I205Controlled Nuclear Localization of p53 in Breast Cancer CellsMohanad Mossalam, Carol S. Lim.206Effect of Transcriptionally Targeted Suicide Gene Therapy for SmallCell Lung Cancer In Vitro and In Vivo by DOTAP/Cholesterol- andAdenoviral-Mediated DeliveryCamilla L. Christensen, Torben Gjetting, Frederik Cramer, Skovgaard Hans.207NF-kB Activity Regulates MSC Accumulation at Tumor SitesRyosuke Uchibori, Hiroyuki Mizuguchi, Tomonori Tsukahara, Masashi Urabe, HiroakiMizukami, Akihiro Kume, Keiya Ozawa.208Dynamics of Therapy of Malignant Melanoma with VesicularStomatitis VirusJyoti Dev, Chetan P. Offord, Diana M. Rommelfanger, Richard G. Vile, Zeljko Bajzer,David Dingli.209Therapeutic Efficacy of a Lentiviral Mediated Thymidine Kinase/Ganciclovir Treatment in an Immunocompetent Rat Malignant GliomaModelJere T. Pikkarainen, Hanna P. Lesch, Haritha Samaranayake, Minna U. Kaikkonen, Ann-Marie Määttä, Seppo Ylä-Herttuala.210Insertion of Transcription Factor Nuclear Factor Kappa B Binding Sitesinto Plasmid DNA Expressing a Suicide Gene Facilitates IncreasedSmall Cell Lung Cancer Cell Death In Vitro Due to Increased NuclearUptakeFrederik Cramer, Camilla L. Christensen, Hans S. Poulsen.211Preirradition Gene Therapy Against Transforming Growth Factor-bSignal Is Radioprotective for the LiverZhao-Chong Zeng, Shi-Suo Du, Ming Qiang, Zheng-Yu Zhang.212Rabbit VX-2 Brain Tumor Model for Development of Improved VectorAdministration TechniquesFarizan Ahmad, Agnieszka Pacholska, Anna Hyvärinen, Venla Tuppurainen, ThomasWirth, Seppo Ylä-Herttuala.213Nano-Flow 2D-HPLC MALDI-TOF MS/MS for Differentially ExpressedProtein Analysis in Breast Cancer Patient SamplesCourtney Haddock, R. B. Holtz, Neil Senzer, Phillip B. Maples, John Nemunaitis.214In Vitro Characterization for In Vivo Translation of a Novel Non-ViralGene Delivery VectorLuke J. Higgins, Gloria L. Hwang, Regina H. Katzenberg, Nishita Kothary, Daniel Y. Sze,Lawrence V. Hofmann.215Altering the Tropism of Herpesvirus saimiri to Selectively InfectHepatocellular Carcinoma (HCC) CellsSusan Turrell, Adrian Whitehouse.216Improved Gene Transfer into Renal Carcinoma Cells Using anAdenovirus VectorShuji Terao, Bishnu Acharya, Toru Suzuki, Katsuyuki Hamada, Hiroyuki Mizuguchi,Akinobu Gotoh.217Prostate Cancer Gene Therapy Using Adenovirus Expressing a NovelApoptosis-Inducing Gene and Its Conjugation with ChemotherapyXiongwen Zhang, Ben Beheshti, Yi Lu.218Development and Preclinical Testing of Large Batches of SNS01-A– An eIF5A-Based Gene Therapy Nanoparticle Designed for theTreatment of Multiple MyelomaCatherine A. Taylor, Zhongda Liu, Terence Tang, Bin Ye, Bruce Galton, Kathleen A.Donovan, John A. Lust, John E. Thompson, Richard Dondero.EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 99Abstract DirectoryThursday, May 20, 2010Poster Session I — continued6:15 PM - 8:15 PMRoom: Exhibit Hall C & B-South219Angiotensin II Type 2 Receptor Gene Mediated Apoptosis of HumanLung Adenocarcinoma A549 CellsYanling Zhang, Ling Zhang, Yongxin Gao, Baihong Chen, Hongwei Li.Hematologic and Immunologic Gene & Cell Therapy I220Modeling X-Linked Chronic Granulomatous Disease Using NeutrophilsDifferentiated from Patient-Derived Induced Pluripotent Stem CellsColin L. Sweeney, Jizhong Zou, Uimook Choi, Bin-Kuan Chou, Linzhao Cheng, Harry L.Malech.221Use of the Natural Human Artemis Promoter To Regulate HumanArtemis Expression Prevents Toxicity and Corrects Artemis DeficientSCID after Ex Vivo Lentiviral Transduction in a Murine Model of theDiseaseMegan M. Multhaup, Kelly Podetz-Pedersen, Sweta Gurram, Andrea Karlen, DebraSwanson, Nikunj V. Somia, Bruce R. Blazar, Morton J. Cowan, R. Scott McIvor, McIvorLab.222Lack of Enhancer-Blocking Activity by 400bp cHS4 Insulator in aHuman T- Lymphoid Cell lineDisha A. Mody, Taihe Lu, Sheng Zhou, John Gray, Brian P. Sorrentino.223Liver-Directed Intravascular Fetal Delivery of scAAV FacilitatesSustained Transgene Expression with Evidence of TransplacentalTrafficking and Possible Vector Integration EventsC. N. Mattar, A. C. Nathwani, N. Dighe, S. Waddington, J. McIntosh, A. Biswas, N. Fisk,A. M. Davidoff, A. David, D. Peebles, A. Nowrouzi, C. Kappel, M. Schmidt, M. Choolani,J. Chan.224Helper-Dependent Adenoviral Vector Gene Therapy Mediates Long-Term Low-Level Correction of Hemophilia A in the Murine Model afterNeonatal Gene TransferChuhong Hu, Fides D. Lay, Racel G. Cela, Masataka Suzuki, Joseph Springer, Ronald W.Busuttil, Brendan Lee, Gerald S. Lipshutz.225Lentiviral Vector Mediated Gene Therapy for the Treatment ofWiskott-Aldrich Syndrome: In Vitro and In Vivo Preclinical Studieswith Human CD34 + CellsSamantha Scaramuzza, Marita Bosticardo, Anna Ripamonti, Maria C. Castiello, LucaBiasco, Giuliana Vallanti, Marina Radrizzani, Anne Galy, Robbert Bredius, BarbaraCappelli, Maria G. Roncarolo, Luigi Naldini, Anna Villa, Alessandro Aiuti.226Development of B-Lineage Specific Lentiviral Vectors for Use in GeneTherapy for B-Cell DisordersBlythe D. Sather, Brigid V. Sterling, Byoung Y. Ryu, Stéphanie Baron, David J. Rawlings.227Development of a Gene Transfer System for Wiskott-AldrichSyndrome Using Foamy Virus VectorsToru Uchiyama, Masaki Shimizu, Fabio Candotti.228Integration Site Distribution in Mice Following Therapeutic GeneTransfer To Treat Beta-ThalassemiaKeshet Ronen, Olivier Negre, Nirav Malani, Maria Denaro, Beatrix Gillet-Legrand, PhilippeLeboulch, Julian D. Down, Emmanuel Payen, Frederic D. Bushman.229Validation of the Tranduction of Patients Hematopoietic ProgenitorCells with a Clinical-Grade Lentiviral Vector Developed for Wiskott-Aldrich Syndrome Gene TherapySalima Hacein-Bey Abina, Elena De Falco, Johanna Blondeau, Sabine Charrier, LaureCaccavelli, Mike Blundell, Alain Fischer, Alessandro Aiuti, Adrian J. Thrasher, MarinaCavazzana-Calvo, Anne Galy.230Generation of an Optimized Lentiviral Vector Encoding a High-Expression fVIII Transgene for Gene Therapy of Hemophilia AJennifer M. Johnston, Robby Moot, Bagirath Gangadharan, Christopher B. Doering, H.Trent B. Spencer.231Biodistribution of a High Dose of Intraarticularly Administered AAV-5Vectors to Lewis RatsScott A. Loiler, Karin de Cortie, Paul P. Tak, Margriet J. Vervoordeldonk.232Ex Vivo Lentiviral Transduction of the Human Purine NucleosidePhosphorylase (PNP) Gene in Bone Marrow Derived HematopoieticStem Cells: An In Vivo Model of Gene Therapy for PNP DeficientT-Cell ImmunodeficiencyKelly M. Podetz-Pedersen, Megan M. Multhaup, Andrea D. Karlen, Debra L. Swanson, K.Scott Baker, Nikunj V. Somia, R. Scott McIvor.233Signed Outside: A Surface Marker System for Transgenic CytoplasmicProteinsVital Wohlgensinger, Reinhard A. Seger, Martin D. Ryan, Janine Reichenbach, Ulrich Siler.869 (Moved from Poster Session III)Myelospecific Self-Inactivating Gammaretroviral Vectors for p47 phoxCGD Gene TherapyVital Wohlgensinger, Christian Brendel, Axel Schambach, Manuel Grez, JanineReichenbach, Reinhard A. Seger, Ulrich Siler.Thursday, May 20 th

100American Society of Gene & Cell TherapyAbstract DirectoryThursday, May 20 thThursday, May 20, 2010Poster Session I — continued6:15 PM - 8:15 PMRoom: Exhibit Hall C & B-SouthGene Regulation234Low Levels of Expression of CD18 Using the pgk Promoter in aFoamy Viral Vector To Treat Animals with Canine Leukocyte AdhesionDeficiencyThomas R. Bauer, Jr., Erik M. Olson, Laura M. Tuschong, James M. Allen, Yi Li, Tanya H.Burkholder, Dennis D. Hickstein, David W. Russell.235A Dual Self-Inactivating Lentiviral Vector System for Mifepristone-Inducible Bicistronic Transgene Expression in Primary NeuralProgenitor CellsMichael A. Mooney, Kenneth H. Fischbeck, Tyler Mark Pierson.236A Novel Human Artificial Chromosome Vector Derived fromChromosome 14 (14HAC): Higher Transgene Expression SystemUsing Sub-Telomere SequencesMinoru Kakeda, Keiko Nagata, Akiko Sano, Kanako Osawa, Akiyo Okazaki, ShingoShitara, Yasuhiro Kazuki, Mitsuo Oshimura, Kazuma Tomizuka.237Effective Gene Delivery to Wounds by Transplantation of Minced SkinParticles Transfected with Adenoviral-VEGFTaro Koyama, Florian Hackl, Pejman Aflaki, Juri Bergmann, Baraa Zuhaili, EmilyWaisbren, Feng Yao, Elof Eriksson.238MicroRNA-122 Regulation Prevents Liver Toxicity of Suicide GeneTherapyGang Wang, Wenhong Tian, Yunfan Liu, Wenjie Tan, Xiaobing Wu.239Regulation of Endogenous GAD67 Expression Using ArtificialTranscription FactorsErika Elgstrand Wettergren, Fredrik Gussing, Maike Sest, Torbjörn Gräslund, CeciliaLundberg.240Enhanced In Vivo Transgene Expression by Two-Step TranscriptionAmplificationGenki Kanda, Hiroshi Ochiai, Hideyoshi Harashima, Hiroyuki Kamiya.241Targeted Knockdown of Serum Response Factor in Hearts of AdultSRF Conditional Knock-Out Mice by AAV9-Mediated Transfer of Cre-RecombinaseStanislas M. Werfel, Andreas Jungmann, Rolf Sprengel, Jürgen A. Kleinschmidt, AlfredNordheim, Hugo A. Katus, Oliver J. Müller.242Pro-Proliferative Functions of Drosophila Small Mitochondrial HeatShock Protein 22 in Human CellsJihoon Ryu, Renu Wadhwa, Ran Gao, Il-Kyu Choi, Genevieve Morrow, Kamal Rajput,Inwook Kim, Sunil C. Kaul, Robert M. Tanguay, Chae-Ok Yun.243Interleukin-(IL)-24 Regulates Epithelial to Mesenchymal Transition(EMT) Transcription FactorsCorbin Goerlich, Manish Shanker, Jiankang Jin, Sendurai Mani, Rajagopal Ramesh.244Transient Epigenetic Gene Therapy as a Rising Arm of a UniversalStem Cell Gene Therapy Platform both for Ex Vivo and In VivoApplicationsRoger Bertolotti.Oligonucleotide & RNAi Therapeutics I245The Application of “Bi-Functional” Short Hairpin RNA in A FurinshRNAand GM-CSF (FANG) Autologous Vaccine for Cancer TherapyZhaohui Wang, Connor Phalon, Padmasini Kumar, Chris M. Jay, Donald D. Rao, Alex W.Tong, Phillip B. Maples, Neil Senzer, John Nemunaitis.246A pH-Sensitive Fusogenic Peptide Modified siRNA-EncapsulatingNanoparticles Exerts the Gene Silencing Synergistically with Tumor-Specific Cleavable PEG-LipidYu Sakurai, Hiroto Hatakeyama, Hidetaka Akita, Motoi Oishi, Yukio Nagasaki, ShirohFutaki, Hideyoshi Harashima.247Systemic Administration of Bifunctional shRNA Lipoplex TargetingPDX-1 for Murine Model of Insulinoma and Pancreatic CancerShihe Liu, Zhaohui Wang, Chris M. Jay, Donald D. Rao, Nancy S. Templeton, Phillip B.Maples, Neil Senzer, F. C. Brunicardi, John Nemunaitis.248Augmentation of Docetaxel Anti-tumor Activity by a Stathmin-Specific Bi-Functional shRNAAlex W. Tong, Yang Yu, Donald D. Rao, Phillip B. Maples, Neil Senzer, John Nemunaitis.249RNAi- and U1i-Mediated Gene TherapyAnnemart Koornneef, Pavlina Konstantinova, Bas Blits, Richard van Logtenstein, TitaRitsema, Puri Fortes, Harald Petry.250Lentiviral Delivery of EzH2 shRNA Inhibits Tumor Growth ofEpithelial Ovarian CancerRamesh B. Batchu, Aamer M. Qazi, Assaad Semaan, Shelly M. Seward, SreedharChamala, Christopher S. Bryant, Robert Morris, Sanjeev Kumar, Christopher Steffes,Masood A. Shammas, Donald W. Weaver.251Prostate Tumor Radiosensitization through PSMA-Aptamer-TargetedsiRNA Knock-Down of DNA Repair PathwaysXiahoua Ni, Yonggong Zhang, Theodore L. DeWeese, Shawn E. Lupold.EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010101Abstract DirectoryThursday, May 20, 2010Poster Session I — continued6:15 PM - 8:15 PMRoom: Exhibit Hall C & B-SouthOligonucleotide & RNAi Therapeutics I252Preclinical Safety and Toxicity Assessment of Stathmin 1 BifunctionalshRNA Formulation Following a Single Intravenous Injection in RatsAnagha P. Phadke, Chris M. Jay, Donald D. Rao, Neil Senzer, Phillip B. Maples, JohnNemunaitis, Alex W. Tong.253Application of siRNA-Containing Nanoparticles for In Vitro and InVivo Gene Silencing in Tumor by Controlling Intracellular TraffickingHiroto Hatakeyama, Erika Ito, Hidetaka Akita, Motoi Oishi, Yukio Nagasaki, ShirohFutaki, Hideyoshi Harashima.254The Novel Comb Shaped Amphiphilic Polyallylamine for PotentialOral Delivery of siRNA to Gastrointestinal Cancers: PhysicochemicalCharacterizations and In Vitro EvaluationsJianfeng Guo, Colin J. Thompson, Woei Ping Cheng, Caitriona O’Driscoll.255Optimalization of Polymerase II sh/miRNA Expression forTherapeutic ApplicationsPiotr Maczuga, Tita Ritsema, Annemart Koorneef, Harald Petry, Sander van Deventer,Pavlina Konstantinova.256The Effect of Helper Lipids on Cationic Lipid-Based siRNA DeliverySystemGuoqin Niu, Hartmut Derendorf, Jeffrey A. Hughes.257c-Cbl shRNA-Expressing Adenovirus Functions as a Sensitizer ofTRAIL-Induced ApoptosisSeeun Oh, So Y. Kim, Bo K. Sun, Dongho Kim, Suhung Lee, Yong J. Lee, Joo-Hang Kim,Jae J. Song.258ncRNAs Originating from the Dystrophin Gene as Biomarker forAssessing Antisense TherapyMatteo Bovolenta, Annarita Armaroli, Marcella Neri, Simona Brioschi, Marina Fabris,Chiara Scotton, Sofia Falzarano, Paola Rimessi, Emanuele Valli, Giovanni Perini, LucianoMerlini, Francesca Gualandi, Alessandra Ferlini.259Efficient In Vivo Delivery of Cholesterol-Conjugated siRNA to theLiver Using Endogenous Chylomicron RemnantKazutaka Nishina, Kie Yoshida, Yoshitaka Uno, Hiroya Kuwahara, Wenying Piao,Hidehiro Mizusawa, Takanori Yokota.Stem Cell Biology260Controlled Nonviral Gene Delivery and Expression Using StableNeural Stem Cell Line Transfected with a Hypoxia-Inducible GeneExpression SystemYoon Ha, MengLu Liu, KeungNyun Kim, DoHeum Yoon.261Non-Viral Carriers Deliver mRNA Encoding Marker Proteins in HeLacells and mRNA Encoding CXCR4 in Mesenchymal Stem CellsJoanna Rejman, Geertrui Tavernier, Joseph Demeester, Stefaan S. D. Desmedt.262Genetic Modification of Neural Stem CellsRavi K. Chandra.263APOA-1 Is a Novel Marker of Erythroid Cell Maturation fromHematopoietic Stem Cells in Mice and HumansTomoko Inoue, Daisuke Sugiyama, Ryo Kurita, Tatsuo Oikawa, Kasem Kulkeaw, HirotakaKawano, Yoshie Miura, Michiyo Okada, Youko Suehiro, Atsushi Takahashi, TomotoshiMarumoto, Hiroyuki Inoue, Norio Komatsu, Kenzaburo Tani.264A Stem Cell Gene Therapy Approach for Enhancing the Efficacy ofBreast Cancer Therapy by Trastuzumab (Herceptin)Ines Beyer, Jonas Persson, ZongYi Li, Ying Liu, Roma Yumul, Andre Lieber.265Ovarian Cancer Stem Cells Are in an Epithelial/Mesenchymal HybridState and Have Multipotential Capacity for DifferentiationRobert Strauss, ZongYi Li, Ying Liu, Nicole Urban, Charles Drescher, Jiri Bartek, AndreLieber.266SB-T-1214 Dramatically Downregulates Stem Cell-Related GeneExpression Profiles in Metastatic Colon Cancer CellsYan Leyfman, Yuan Wang, Iwao Ojima, Galina Botchkina.267Identifying Genes and Signaling Pathways Regulating the QuiescentState in Muscle Stem (Satellite) CellsKristy Boyle, Jeffrey S. Chamberlain.268Pathway Analysis of Multipotent Mesenchymal Stromal Cells UsingBacMam ToolsLucas Chase, Thomas Machleidt, Mahendra S. Rao, Uma Lakshmipathy.269The Placental Microvasculature Is a Rich Source of HighlyProliferative Endothelial Colony Forming Cells Capable of DevelopingFunctioning Vessels In VivoBrian M. Rapp, Reza Saadatzadeh, Janak Bhasvar, Richard Ofstein, Michael P. Murphy.270microRNA Function during Human Mesenchymal Stem Cell AdipogenicDifferentiationAnnette Enright, Vladimir Benes, Georgina Shaw, Frank Barry, Linda Howard.Thursday, May 20 th

102American Society of Gene & Cell TherapyAbstract DirectoryThursday, May 20 thThursday, May 20, 2010Poster Session I — continued6:15 PM - 8:15 PMRoom: Exhibit Hall C & B-SouthStem Cell Biology271A Novel Fluorescence/Fluorine MRI Dual-Mode Reagent for CellTracking and Determination of Cell FateAnthony G. Balducci, Brooke Helfer, Amy K. Wesa, Jelena Janjic, Eric Ahrens.272The Stromal Vascular Fraction of Human Term Placenta Is a RichSource of Pluripotent Mesenchymal Stem CellsMohammad R. Saadatzadeh, Janak Bhavsar, Brian M. Rapp, Peter J. Moreno, MichaelP. Murphy, Michael P. Murphy.273The HSV-2 Protein, ICP10PK, Potentiates the NeuroprotectiveActivity of Stem CellsKyle A. Wilson, Jennifer M. Laing, Aurelian Laure.Cell Processing and Vector Production I274Process Improvements for cGMP Manufacture of Lexgenleucel-T forHIV TreatmentReuben Cohen, Yelena Skripchenko, Tony Encinas, Gerard J. McGarrity, Shuyuan Zhang.275TAG Vaccine Clinical Trial ManufacturingPhillip B. Maples, Padmasini Kumar, Yang Yu, Beena O. Pappen, Joseph Kuhn, JohnNemunaitis.276Development and GMP Validation of Large Scale LentiviralTransduction of CD34+ Cells for Metacromatic Leukodystrophy andWiskott-Aldrich Syndrome Gene Therapy Clinical TrialsGiuliana Vallanti, Chiara Pozza, Francesca Rossetti, Letizia Martelli, Giuseppina Marano,Alessandra Gatti, Lucia Turchetto, Paola Massariello, Monica Salomoni, Claudia Benati,Sergio Fracchia, Alessandro Lorini, Marco Dieci, Raul Ziliotto, Alessandra Biffi, AlessandroAiuti, Claudio Bordignon, Luigi Naldini, Marina Radrizzani.277Large Scale rVSV Viral Vector Production in a cGMP FacilityLara J. Ausubel, Marcia Meseck, Ivy Derecho, Patricia Lopez, Christine Knoblauch, RossMcMahon, Jonathan Anderson, Nina Dunphy, Valerie Quezada, Mathew Luo, David Hsu,Savio Woo, Larry Couture.278Challenges in the Manufacturing of Retroviral Gene Therapy VectorsAna F. Rodrigues, Ana I. Amaral, Manuel J. T. Carrondo, Paula M. Alves, Ana S.Coroadinha.279Production of cGMP Grade Lentiviral VectorLara J. Ausubel, Christine Knoblauch, Patricia Lopez, Ross McMahon, Jonathan Anderson,Valerie Quezada, Nina Dunphy, Ivy Derecho, Mathew Luo, David Hsu, Larry Couture.280Design and Operation of a New State-of-the-Art Multi-Product cGMPCleanroom Facility for Vector Production and Cell ManipulationJohannes C. M. van der Loo, William P. Swaney, Kathryn Mangopoulos, MicheleBeuerlein, Diana L. Nordling, Lilith R. Reeves, Punam Malik.281Highly Efficient Manufacturing of Clinical Grade Lentiviral Vector in aNew, State of the Art Academic Good Manufacturing Practice (GMP)FacilityGerhard Bauer, Joseph Anderson, Matt Lindsey, Jan Nolta.282The Role of JNK in Lentivirus Gene TransferMeng Horng Lee, Roshan Padmashali, Stelios T. Andreadis.Late Breaking Science I922HSV-mediated Transfer of the Sox11 Gene and Peripheral NerveRegenerationXiaotang Jing, Shaohua Huang, Joseph C. Glorioso, Kathryn M. Albers923Real-Time In Vivo Imaging of Neural Stem Cells for Targeted Therapyof MedulloblastomaMargarita Gutova, Vazgen Kandalyyan, Ira Harutyunyan, Joseph Najbauer, Rex A.Moats, Gregory M. Shackleford, Michael E. Barish and Karen S. Aboody924Clinical Trial Entry of a Novel Prodrug Activator Gene TransferTechnology for the Treatment of CancerH. Gruber, C. Ibanez, A. daSilva, W. Gunzburg, D. Pertschuk, D. Gessner, N. Kasahara,C.R. Logg, O. Perez, D. Ostertag, J. Robbins, D.J. Jolly925Integration-Defective Lentiviral Vectors for Hemophilia: A SaferPlatform for Immune Tolerance Induction and Reduced GenotoxicityJanka Mátrai, Alessio Cantore, Cynthia C. Bartholomae, A Annoni, Abel Acosta-Sanchez, Ermira Samara-Kuko, Liesbeth De Waele, Ling Ma, Tim C. Nichols, Christofvon Kalle, Roncarolo, Marie-Gracia, Marinee K.L. Chuah, Manfred Schmidt, ThierryVandenDriessche, Luigi Naldini926Abstract Withdrawn927Targeting CD70 Positive Malignancies with T cells Expressinga CD27-Zeta Chimeric Antigen Receptor Reveals ImportantCostimulatory Role of CD27D. Shaffer, B Savoldo, G. Dotti, D Spencer, S. Kenney, C.M. Rooney, S. GottschalkEXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010103Abstract DirectoryThursday, May 20, 2010Poster Session I — continued6:15 PM - 8:15 PMRoom: Exhibit Hall C & B-SouthLate Breaking Science I928Engineering Aptamers Against HIV-1 RT for Improved AntiviralBioactivityMargaret J. Lange, Angela S. Whately, Donald H. Burke929Directed Integration of New Insulated Lentiviral Vectors to theHeterochromatin towards Safer Gene Transfer to Stem CellsAlexandre Artus, Caroline Duros, Yaïr Botbol, Simone Schultz, Manfred Schmidt, Christofvon Kalle, Marc Lavigne, Odile Y Cohen-Haguenauer930Genotoxic Potential of scAAV Vectors in Mouse LiverLucia E. Rosas, Kimberly Zaraspe, Douglas M. McCarty931In vivo Persistence of ex vivo Expanded CCR7+CD45RA+ T CellsUsing a RetroNectin Stimulation MethodTatsuji Enoki, Nobuko Muraki, Akiko Kato, Mitsuko Ideno, Junichi Mineno932Self-inactivating ASLV Based Vectors for the Gene Therapy of X-CGDKerstin B. Kaufmann, Julia Suerth, Christian Brendel, Axel Schambach, ChristopherBaum, Manuel GrezThursday, May 20 th

104American Society of Gene & Cell TherapyAbstract DirectoryFriday, May 21 stFriday, May 21, 2010Plenary Abstract Session 300Plenary Abstract Session8:00 AM - 10:00 AMRoom: Marriott Ballroom Salons 1, 2 & 3283 8:05 AMTherapeutic Transgene Expression in Patient-Specific iPS Cells afterSelection of “Safe Harbors” for Lentiviral Vector IntegrationEirini P. Papapetrou, Gabsang Lee, Nirav Malani, Isabelle Riviere, Frederic D. Bushman,Lorenz Studer, Michel Sadelain.284 8:25 AMA Novel Lentiviral Expression System Reveals Patchwork ColonyFormation during Reprogramming to Induced Pluripotent Stem CellsEva Warlich, Johannes Kuehle, Tobias Cantz, Martijn Brugman, Tobias Maetzig, MelanieGalla, Christine Völkel, Adam Filipczyk, Stephan Halle, Hannes Klump, Hans Schöler,Timm Schroeder, Christopher Baum, Axel Schambach.285 8:45 AMTargeted Genomic Modification and Inactivation of the CCR5 GeneUsing PNA-Induced Homologous RecombinationErica B. Schleifman, Ranjit S. Bindra, Jean Leif, Nicole Ali McNeer, Jacob Del Campo,Faye Rogers, Pradeep Uchil, Leonard D. Shultz, W. Mark Saltzman, Priti Kumar, DaleGriener, Peter M. Glazer.286 9:05 AMDetermining the Specificity of Zinc Finger Nucleases by AnalyzingInsertion Site Distribution of Integrase Defective Lentiviral Vectors(IDLV) Trapped into DNA Double Strand BreaksRichard Gabriel, Angelo Lombardo, Anne Arens, Pietro Genovese, Michael C. Holmes,Philip D. Gregory, Manfred Schmidt, Luigi Naldini, Christof von Kalle.287 9:25 AMSystemic Administration of Dendrimer- and Aptamer-siRNAConjugates Efficiently Suppresses HIV-1 InfectionJiehua Zhou, Preston C. Neff, Xiaoxuan Liu, Jane Zhang, Haitang Li, Piotr Swiderski, LingPeng, Ramesh Akkina, John J. Rossi.288 9:45 AMCASPALLO: Phase I Clinical Trial of Allodepleted T Cells Transducedwith Inducible Caspase 9 Suicide Gene after Haploidentical Stem CellTransplantationAntonio Di Stasi, Siok K. Tey, Yuriko Fujita, Russell Cruz, Caridad Martinez, AlanaKennedy-Nasser, George Carrum, Carlos A. Ramos, Stephen M. Gottschalk, KarinStraathof, Lin Yu-Feng, Enli Liu, April Durett, Bambi Grilley, Hao Liu, Barbara Savoldo,Eric Yvon, Teresita Lopez, Oumar Diouf, Deborah Lyon, Adrian Gee, Ellen Vitetta, JohnSchindler, Catherine M. Bollard, Robert A. Krance, David M. Spencer, Gianpietro Dotti,Cliona M. Rooney, Helen E. Heslop, Malcolm K. Brenner.Oral Abstract Session 320Clinical Gene & Cell Therapy Oral Abstract Session2:00 PM - 4:00 PMRoom: Marriott Ballroom Salons 2 & 3289 2:00 PMTherapeutic DNA Vaccination Followed by Standard-of-Care Therapyin Patients with Chronic Hepatitis C: A Rapid Clearance of ViremiaMatti Sallberg, Lars Frelin, Helmut M. Diepolder, Maria C. Jung, Iacob Mathiesen,Michael Fons, Gustaf Ahlen, Margaret Chen, Ola Weiland.290 2:15 PMSustained Alpha-Sarcoglycan Gene Expression in LGMD2D FollowingGene TransferJerry R. Mendell, Louise R. Rodino-Klapac, Xiomara Rosales-Quintero, Brian D. Coley,Gloria Galloway, Sarah Lewis, Vinod Malik, Christopher J. Shilling, Barry J. Byrne,Thomas Conlon, Katherine J. Campbell, William G. Bremer, Christopher M. Walker, ZarifeSahenk, K. Reed Clark.291 2:30 PMAdvanced Generation RGD-Modified Oncolytic Adenovirus ICOVIR-7in the Treatment of Cancer Refractory to Other ModalitiesPetri Nokisalmi, Sari Pesonen, Sophie Escutenaire, Mari Raki, Vincenzo Cerullo, RamonAlemany, Juanjo Rojas, Maria Rajecki, Lotta Kangasniemi, Anna Kanerva, Timo Joensuu,Laura Ahtiainen, Akseli Hemminki.292 2:45 PMFinal Results of Phase I Trial of GMCSF Gene-TGFb2 Antisense GeneAutologous Tumor Cell (TAG) Vaccine in Advanced CancerJohn Nemunaitis, Padmasini Kumar, Neil Senzer, Joseph Kuhn, Minal Barve, JairoOlivares, Gerald Edelman, Cynthia Bedell, Yang Yu, Mitchell Magee, Beena O. Pappen,Gladice Wallraven, Alex W. Tong, Phillip B. Maples.293 3:00 PMAdministration of Tumor-Specific Cytotoxic T Lymphocytes Engineeredto Resist TGF-ß to Subjects with EBV-Associated LymphomasCatherine M. Bollard, Gianpietro Dotti, Stephen Gottschalk, Enli Liu, Andrea M. Sheehan,George Carrum, Hao Liu, Chung-Che Chang, Adrian P. Gee, Malcolm K. Brenner, Helen E.Heslop, Cliona M. Rooney.294 3:15 PMEfficient Engraftment of MGMTP140K Gene-Modified CD34+ CellsFollowing Nonmyeloablative BCNU Conditioning in Patients withGlioblastomaJennifer E. Adair, Brian C. Beard, Alexander Spence, Jason Rockhill, Daniel L. Silbergeld,Robert Rostomily, Pamela Becker, Marc Chamberlain, Maciej Mrugala, Hans-Peter Kiem.295 3:30 PMThymic Renewal and Anti-Leukemic Effect in Adults afterHaplodentical Transplantation and Suicide Gene TherapyLuca Vago, Giacomo Oliveira, Maddalena Noviello, Corrado Soldati, Domenico Ghio,Roberto Nicoletti, Immacolata Brigida, Alessandro Aiuti, Maria Teresa Lupo Stanghellini,Jacopo Peccatori, Attilio Bondanza, Katharina Fleischhauer, Claudio Bordignon, FabioCiceri, Chiara Bonini.EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010105Abstract DirectoryFriday, May 21, 2010Oral Abstract Session 320 I — continuedClinical Gene & Cell Therapy Oral Abstract Session2:00 PM - 4:00 PMRoom: Marriott Ballroom Salons 2 & 3296 3:45 PMUpdate on a Clinical Gene Therapy Trial for Adenosine DeaminaseDeficient Severe Combined Immune Deficiency (ADA-SCID)Kit L. Shaw, Yeong “Christopher” Choi, Linda Muul, Robert Sokolic, Denise A. Carbonaro,Alan Ikeda, Monika Smogorzewska, Jayashree Jagadeesh, Elizabeth Garabedian, AmiShah, Neena Kapoor, Michael S. Hershfield, Fabio Candotti, Donald B. Kohn.Oral Abstract Session 321RNA Virus Vectors2:00 PM - 4:00 PMRoom: Virginia Suite297 2:00 PMSensitive In Vivo Models To Assess the Risk of InsertionalMutagenesis in the Liver upon Vector Systemic DeliveryMarco Ranzani, Daniela Cesana, Manfred Schmidt, Francesca Sanvito, FabrizioBenedicenti, Cynthia Bartholomä, Maurilio Ponzoni, Alessio Cantore, Lucia Sergi Sergi,Claudio Doglioni, Christof VonKalle, Luigi Naldini, Eugenio Montini.298 2:15 PMSystemic Injection in a Tumor Prone Mouse Unravels the ResidualGenotoxicity of Self-Inactivating Lentiviral VectorsDaniela Cesana, Marco Ranzani, Cynthia Bartholomä, Manfred Schmidt, FabrizioBenedicenti, Monica Volpin, Christof VonKalle, Luigi Naldini, Eugenio Montini.299 2:30 PMSpecific Insertions of Zinc Finger Domains into Gag-Pol YieldsEngineered Retroviral Vectors with Selective Integration PropertiesKwang-il Lim, Ryan Klimczak, Julie Yu, David Schaffer.300 2:45 PMThe D4Z4 Insulator Protects Retrovirus Vectors from Silencing inStem CellsSylvie Rival-Gervier, Susan Anderson, Mandy Lo, Peter Pasceri, James Ellis.301 3:00 PMExpression of the LEDGF Integrase Binding Domain (IBD) SeverelyRestricts HIV-1 Replication and Drives Evolution of PhenotypicallyDistinctive Integrase MutantsDyana T. Saenz, Anne Meehan, Mary E. Peretz, Eric M. Poeschla.302 3:15 PMTransient and Highly Efficient Delivery of Sleeping BeautyTransposase and Flp Recombinase mRNA in Target Cells Via RT-Deficient Retroviral ParticlesMelanie Galla, Axel Schambach, Tobias Maetzig, Niels Heinz, Zsuzsanna Izsvak, ZoltanIvics, Christopher Baum.303 3:30 PMErasable Non-Integrating RNA Replicon Vectors for Generation ofImmaculate iPS Cells Free from Transgenes and Sequence-InterferenceHiroshi Ban, Noemi Fusaki, Toshiaki Tabata, Koichi Saeki, Akihiro Iida, Makoto Inoue,Mamoru Hasegawa.304 3:45 PMSelf-Inactivating Alpharetroviral Vectors with a Split-PackagingDesignJulia D. Sürth, Tobias Mätzig, Melanie Galla, Ute Modlich, Christopher Baum, AxelSchambach.Oral Abstract Session 322AAV Vectors: Vector Biology2:00 PM - 4:00 PMRoom: Marriott Ballroom Salon 1305 2:00 PMDissecting rAAV Integration Frequency in Non-Human Primates byDeep SequencingAli Nowrouzi, Magalie Penaud-Budloo, Christine Kaeppel, Anne Arens, Caroline Le Guiner,Adrien Leger, Karim Zaoui, Christian Weber, Richard O. Snyder, Christof von Kalle,Philippe Moullier, Manfred Schmidt.306 2:15 PMNon-Canonical Integrating AAV Vectors as a Safe Tool for the Futureof Gene TherapyLeszek Lisowski, Zhongya Wang, Ashley Lau, Feijie Zhang, Markus Grompe, Mark A.Kay.307 2:30 PMInteraction with Homologous Recombination Pathways Leads To Lossof Functional Recombinant AAV (rAAV) GenomesMarcela P. Cataldi, Douglas M. McCarty.308 2:45 PMHigh-Throughput Sequencing of AAV Vector Integrants To AssessPotential for GenotoxicityHojun Li, Nirav Malani, Shari R. Hamilton, Alexander Schlachterman, Giulio Bussadori,Shyrie E. Edmonson, Rachel Shah, Federico M. Mingozzi, J. F. Wright, Valder R. Arruda,Frederic D. Bushman, Katherine A. High.309 3:00 PMA Self-Complimentary rAAV Vector Genome but Not Variations in theCapsid Sequence Magnifies the Innate Immune Response FollowingLiver Directed DeliveryAshley T. Martino, Masataka Suzuki, Brendan Lee, Roland W. Herzog.310 3:15 PMA Proteomic Analysis of the Protein Composition in Recombinant AAVVector PreparationsBiao Dong, Xunbao Duan, Fayaz Khazi, Kirk Chu, Jihong Dai, Jenni A. Snyder, Hui Lu,Weidong Xiao.311 3:30 PMDownregulation of DNA-Damage Response Proteins in PostmitoticTissues Correlates with Increased AAV TransductionJasmina Lovric, Miguel Mano, Lorena Zentilin, Mauro Giacca.Friday, May 21 st

106American Society of Gene & Cell TherapyAbstract DirectoryFriday, May 21 stFriday, May 21, 2010Oral Abstract Session 322 — continuedAAV Vectors: Vector Biology2:00 PM - 4:00 PMRoom: Marriott Ballroom Salon 1312 3:45 PMInnate Immune Response towards Adeno-Associated Viral (AAV)Vectors in Human Liver Non-Parenchymal CellsMarianna Hoesel, Mathias Broxtermann, Hanna Janicki, Knud Esser, Silke Arzberger,Miriam John von Freyend, Dirk Stabenow, Percy Knolle, Michael Hallek, Ulrike Protzer,Hildegard Buening.Oral Abstract Session 323Gene Therapy for Lysosomal Storage Diseases andOther Genetic Disorders2:00 PM - 4:00 PMRoom: Delaware Suite313 2:00 PMTowards a Safe and Effective Gene Therapy Approach for Globoid CellLeukodystrophyIlaria Visigalli, Silvia Ungari, Bernhard Gentner, Sabata Martino, Daniela Ungaro, LetterioS. Politi, Lucia Sergi Sergi, Ubaldo Del Carro, Angelo Quattrini, Luigi Naldini, AlessandraBiffi.314 2:15 PMMesenchymal Stem Cell Therapy for the Twitcher Mouse Model ofKrabbe’s DiseaseCynthia Ripoll, Mette Flaat, Jessica Eiermann, Jeanne Perkins, Brittni Scruggs, MarjorieMcCants, Michelle Eagle, William Wimley, Cynthia Trygg, Jeffrey Gimble, Bruce Bunnell.315 2:30 PMTherapeutic Efficacy of Hematopoietic Stem Cell Gene Therapy forHurler Type 1 MucopolysaccharidosisStefania Delai, Ilaria Visigalli, Letterio S. Politi, Carmela Di Domenico, Emanuela Mrak,Riccardo Brambilla, Federica Cerri, Daniela Ungaro, Merel Stok, Francesca Sanvito,Ubaldo Del Carro, Alessandro Rubinacci, Katherine P. Ponder, Angelo Quattrini, Paola DiNatale, Luigi Naldini, Alessandra Biffi.316 2:45 PMTherapeutic Potential of Genetically Modified Neural Stem Cells(NSCs) in a Mouse Model of Globoid Cells Leukodystrophy (GLD)Margherita Neri, Alessandra Ricca, Silvia Ungari, Ilaria Visigalli, Alessandra Biffi, Ilaria DiGirolamo, Sabata Martino, Lucia Sergi Sergi, Luigi Naldini, Angela Gritti.317 3:00 PMAdeno-Associated Virus and Tetanus Toxin Fragment C Based Vectorsfor Gene Therapy in the CNSCarlos Gay-Antaki, John H. Wolfe.318 3:15 PMLineage Specific Lentiviral Mpl Expression Rescues HematopoieticStem Cell Defects in Mpl-/- MiceDirk Heckl, Daniel C. Wicke, Johann Meyer, Axel Schambach, Johanna Krause, MatthiasBallmaier, Christopher H. Baum, Ute Modlich.319 3:30 PMSafety of Gene Therapy for ThalassemiaRiccardo Mezzadra, Emanuela Roselli, Claudia Rossi, Francesca Tiboni, GiacomoMandelli, Sarah Marktel, Fulvio Mavilio, Giulietta Maruggi, Marco Andreani, GuidoLucarelli, Giuliana Ferrari.320 3:45 PMLong-Term Phenotypic Correction of Skin by Fetal Gene Transfer in aLethal Murine Model of Epidermolysis BullosaMasayuki Endo, Philip W. Zoltick, Antenata Radu, Jiang Qiujie, Chihiro Matsui, Peter M.Marinkovich, Jouni Uitto, Alan W. Flake.Oral Abstract Session 324Physical Methods of Delivery2:00 PM - 4:00 PMRoom: Wilson ABC321 2:00 PMBile Duct Infusion of Plasmid DNA Mediated High Level of TransgeneExpression in Rat LiverXuan Jiang, Derek Leong, Deng Pan, Hai-Quan Mao.322 2:15 PMImage-Guided, Computer-Controlled Hydrodynamic Gene Delivery toLiver Results in Therapeutic Level of Human Alpha-1 Antitrypsin inPigs and DogsKenya Kamimura, Takeshi Suda, Guisheng Zhang, Dexi Liu.323 2:30 PMTargeting Magnetic Nanoparticles Impregnated with Adenovirus toStented Arteries Using Uniform-Field Induced Magnetization in theRat Carotid Model of RestenosisMichael Chorny, Ilia Fishbein, Richard Adamo, Robert J. Levy.324 2:45 PMUltrasound-Activated Microbubbles for Gene Transfer: In VivoEfficiency and Confocal Microscopy Real Time IntracellularInvestigationsAnthony Delalande, Patrick Midoux, Michiel Postema, Chantal Pichon.325 3:00 PMLong-Term Gene Expression after Hydrodynamic Delivery of SleepingBeauty Transposons to Canine Liver Using Balloon CathetersPerry B. Hackett, Myra Urness, Jason B. Bell, Erik R. Olson, Elena L. Aronovich, R. ScottMcIvor.326 3:15 PMEfficient Microbubble- and Ultrasound-Mediated Plasmid DNATransfer into a Specific Rat Liver Lobe Via a Targeted Injection andAcoustic Exposure Using a Novel Ultrasound SystemShuxian Song, Misty L. Noble, Liping Chen, Samuel S. Sun, Andrew A. Brayman, CarolH. Miao.EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010107Abstract DirectoryFriday, May 21, 2010Oral Abstract Session 324 — continuedPhysical Methods of Delivery2:00 PM - 4:00 PMRoom: Wilson ABC327 3:30 PMA Novel Prototype Device for Electroporation-Enhanced DNA VaccineDelivery to Both Skin and MuscleFeng Lin, Jay McCoy, Xuefei Shen, Janess Mendoza, Kate E. Broderick, Jian Yan, SteveKemmerrer, David B. Weiner, Niranjan Y. Sardesai.328 3:45 PMSafety and Feasibility of Transvenous Limb Perfusion with Saline inHuman Muscular DystrophyWilliam Powers, Zheng Fan, Keith Kocis, Robert Valley, Manisha Chopra, James Howard,Jr, Joseph Muenzer.Oral Abstract Session 325Cancer-Targeted Gene & Cell Therapy2:00 PM - 4:00 PMRoom: Thurgood Marshall W334 3:15 PMTumor-Selectivity of Replication-Competent Retrovirus (RCR) VectorsRegulated by Prostate-Specific Promoters and Cytotoxic Effect ofSuicide Gene Therapy Mediated by RCR Vectors In VitroShuichi Kamijima, Takahiro Kimura, Kazunori Haga, Kei Hiraoka, Akihito Inagaki,Christopher R. Logg, Chinghai Kao, Bernard H. Bochner, Noriyuki Kasahara.335 3:30 PMTranslational Phase I Study in Advanced Cancer Patients of Dual-Function Autologous (FANG) Vaccine Incorporating BifunctionalshRNA furin and GMCSF Transgene ExpressionNeil Senzer, Padmasini Kumar, Joseph Kuhn, Minal Barve, Cynthia Bedell, Yang Yu, AlexW. Tong, Phillip B. Maples, John Nemunaitis.336 3:45 PMEfficient Gene Transfer in Quiescent Healthy and Cancer B Cells by aMeasles Virus gp Pseudotyped LVCecilia Frecha, Caroline Costa, Camille Levy, Didier Negre, Andrea Maisner, Stephen J.Russell, Nicholas Rachinel, Gilles Salles, Francois-Loic Cosset, Els Verhoeyen.Oral Abstract Session 326Hematologic/Immunologic: Basic2:00 PM - 4:00 PMRoom: Maryland Suite329 2:00 PMA Genetically Engineered Multifunctional Vector for HER2 TargetedCancer Suicide Gene TherapyYuhua Wang, Arash Hatefi.330 2:15 PMComparative Analysis of Enzyme and Pathway Engineering Strategiesfor Suicide Gene Therapy ApplicationsAdam J. Johnson, Andressa Ardiani, Kinta Serve, Marilyn Sanchez-Bonilla, Margaret E.Black.331 2:30 PMConditional and Effective Gene Knock-Down in ProangiogenicMacrophages To Disrupt Tumor AngiogenesisFerdinando Pucci, Roberta Mazzieri, Bernhard Gentner, Luigi Naldini, Michele De Palma.332 2:45 PMCell Fusion between Mesenchymal Stem Cells and Cancer Cells: AMechanism of Cancer ProgressionYan Xiao, Dirk H. Hondmann, Carla J. Aldrich, Chenzhong Kuang.333 3:00 PMNext-Generation Lentiviral Cell Fate Control Gene Therapy Based onEngineered Variants of Human Deoxycytidine KinaseAnton Neschadim, Arnon Lavie, Takeya Sato, Daniel H. Fowler, Vladimir Ponomarev,Jeffrey A. Medin.337 2:00 PMSafely Exploiting Hematopoeitic Stem and Progenitor Cell SpecificmicroRNAs To Target Transgene Expression to the DifferentiatedProgenyBernhard Gentner, Alice Giustacchini, Francesco Boccalatte, Massimo Saini, Giulia Schira,Luigi Naldini.338 2:15 PMTherapeutic Fetal Hemoglobin Production in Erythroid Progeny ofNormal and b-Thalassemic Human CD34 + Cells Using LentiviralVectors Encoding g-Globin or shRNA To Down Modulate theTranscriptional Repressor BCL11AAndrew Wilber, Vijay G. Sankaran, Phillip W. Hargrove, Yoon-Sang Kim, EleniPapanikolaou, Nicholas P. Anagnou, Stuart H. Orkin, Arthur W. Nienhuis, Derek A.Persons.339 2:30 PMPotentially Therapeutic Levels of Fetal Hemoglobin in ErythroidProgeny of Normal and b-Thalassemic CD34 + Cells FollowingLentivirus-Mediated Delivery of a Zinc-Finger TranscriptionalActivator Targeting the g-Globin Gene PromotersAndrew Wilber, Ulrich Tschulena, Phillip W. Hargrove, Yoon-Sang Kim, Carlos F. Barbas,III, Derek A. Persons, Arthur W. Nienhuis.340 2:45 PMDevelopment of an S/MAR Based Episomal Vector of a Specific Zinc-Finger Activator That Mediates Gamma-Globin Gene Activation, forthe Gene Therapy of HemoglobinopathiesEleana Stavrou, Eleni Lagadinou, Nikolas Zoumbos, Alexandros Spyridonidis, CarlosBarbas, III, Kenneth Peterson, Aglaia Athanassiadou.Friday, May 21 st

108American Society of Gene & Cell TherapyAbstract DirectoryFriday, May 21 stFriday, May 21, 2010Oral Abstract Session 326— continuedHematologic/Immunologic: Basic2:00 PM - 4:00 PMRoom: Maryland Suite341 3:00 PMEngineered Human Regulatory T Cells Expressing Lentiviral PDL1under Cell Fate Control Prevent Lethal Xenogeneic GVHDShoba Amarnath, James Wang, Courtney Mangus, James Riley, Bruce Levine, Carl June,Jeffrey Medin, Daniel Fowler.342 3:15 PMCorrection of Murine Hemophilia A Following NonmyeloablativeTransplantation of Hematopoietic Stem Cells Engineered To Expressa Bioimproved Human FVIII Using a Safety-Augmented, B-LymphoidLineage-Restricted Lentiviral VectorAli Ramezani, Sara Karandish, Lynnsey A. Zweier-Renn, Teresa S. Hawley, Robert G.Hawley.343 3:30 PMLentiviral Vectors Containing an Endogenous Btk Promoter RestoreB and Myeloid Lineage Expression and Function in a Murine Model ofX-Linked AgammaglobulinemiaHannah M. Kerns, Byoung Y. Ryu, Brigid V. Stirling, Blythe D. Sather, AlexanderAstrakhan, Stephanie Humblet-Baron, Denny Liggitt, David J. Rawlings.344 3:45 PMEarly Gestational Gene Transfer of IL-10 by Lentiviral Vector CanPrevent Arthritis in a Murine ModelJessica L. Roybal, Masayuki Endo, Antoneta Radu, Carlyn Todorow, Philip W. Zoltick,Alan W. Flake.Poster Session II6:30 PM - 8:30 PMRoom: Exhibit Hall C & B-SouthRNA Virus Vectors I345Expression Profile and Epigenetic Landscape Influence in a Cell-Specific Fashion Integration Site Selection and In Vivo Distribution ofMLV-Vector in PatientsLuca Biasco, Alessandro Ambrosi, Danilo Pellin, Cynthia Bartholomae, ImmacolataBrigida, Maria Grazia Roncarolo, Clelia Di Serio, Christof Von Kalle, Manfred Schmidt,Alessandro Aiuti.346High-Definition Mapping of Retroviral Integration Sites Defines theFate of Allogeneic T Cells after Donor Lymphocyte InfusionAlessandra Recchia, Claudia Cattoglio, Danilo Pellin, Giulietta Maruggi, Serena KimiPerna, Alessandro Ambrosi, Clelia Di Serio, Nirav Malani, Frederic D. Bushman, CynthiaBartholomae, Manfred Schmidt, Chiara Bonini, Fulvio Mavilio.347Genome Wide Characterization of Insertion Profiles of IntegrationDeficient Lentiviral Vectors Using Two-Sided Non-Restrictive andStandard LAM-PCRWei Wang, Cynthia C. Bartholomae, Anne Arens, Richard Gabriel, Hanno Glimm, Christofvon Kalle, Manfred Schmidt.348Multiple Pathways Facilitate Transduction of Quiescent HumanCD34+ Cells by HIV-1 VectorsCathy X. Wang, Charles DeRossi, Bruce E. Torbett.349Targeted Lentiviral Gene Delivery to Cells Expressing c-fms or IL-2ReceptorAnil Chandrashekran, Giedre Milinkeviciute, Rosana Cardoso, Fouzia Abdulrasul, Shao-AnXue, Nick Dibb, Carol Readhead, Colin Casimir.350Regulation of Transgene Expression In Vivo by ProteasomalDegradationKhalid Tai, Fredrik Gussing, Christina Isaksson, Luis Quintino, Mari Iwamoto, Tom J.Wandless, Cecilia Lundberg.351Clonal Analysis Allows Characterization and Risk Assessmentof Viral-Cellular Fusion Transcripts Generated by TranscriptionalTermination Read-Through in Keratinocytes Transduced with Self-Inactivating Retroviral VectorsDavid Almarza, Fernando Larcher, Rodolfo Murillas, Fulvio Mavilio.352Evaluation of Cytokine Effects on Lentiviral Transduction of HumanCD34 + CellsNaoya Uchida, Kareem N. Washington, Matthew M. Hsieh, John F. Tisdale.353Towards Quantitative High Throughput Clonality Screening:Redefining the Frontier of Retroviral Integration AnalysisTroy B. Hawkins, Aparna Jasti, Jessica Dantzer, Nate Van Dusen, Brandon Downing,Sean Mooney, Mary C. Dinauer, Keithanne Mockaitis, Kenneth G. Cornetta.354Development of a pCL20c-Backbone Based HIV Lentivirus Vector ThatAchieves Efficient Functional Correction of Neutrophils Arising fromTransduced CD34+ Hematopoietic Progenitor Cells of Patients withX-Linked Chronic Granulomatous DiseaseUimook Choi, Robert E. Throm, Elizabeth M. Kang, Suk See DeRavin, Narda Theobald,Gilda M. Linton, Brian P. Sorrentino, Mary C. Dinauer, John T. Gray, Harry L. Malech.355Packaging Heterologous Retroviral Vectors into HIV-1 Viral ParticlesAdam S. Cockrell, Henriette van Praag, Nicholas Santistevan, Thomas J. McCown, BonitaBlake, Hong Ma, John Olsen, Tal Kafri.356High Throughput Vector Integration Analysis with SeqMap 2.0Troy B. Hawkins, Jessica Dantzer, Brandon Peters, Mary Dinauer, Keithanne Mockaitis,Sean Mooney, Kenneth G. Cornetta.EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010109Abstract DirectoryFriday, May 21, 2010Poster Session II— continued6:30 PM - 8:30 PMRoom: Exhibit Hall C & B-SouthRNA Virus Vectors I357‘Self’ Marker CD47 on Viral EnvelopesNisha Sosale, Richard K. Tsai, Irena Ivanovska, Philip W. Zoltick, Dennis E. Discher.358Lentiviral Microarrays for High-Throughput and Real-Time Monitoringof Gene Expression DynamicsJun Tian, Stella Allimperti, Pedro Lei, Stelios T. Andreadis.359Fibrin-Conjugated Pseudotyped Lentivirus for Cell-Controlled andSpatially Localized Gene Delivery on Microarrayed SurfacesRoshan Padmashali, Pedro Lei, Stelios Andreadis.360Improved Transduction Efficiency of Human Amniotic MesenchymalStem Cells Using Optimized Lentiviral VectorsF. Pisano, P. Danieli, E. Cervio, C. Ciuffreda, M. Roccio, G. Viarengo, M. Gnecchi.361Purification of Lentivirus Vector by Iodixanol Self-Forming DensityGradientJulia Transfiguracion, Sven Ansorge, Rosa Tran, Amine Kamen.AAV Vectors II362rAAV-Mediated Delivery of Micro RNA Scavengers Leads to Efficientand Stable Knock-Down of Cognate Micro RNAs, Upregulation ofTheir Natural Target Genes and Phenotypic Changes in MiceJun Xie, Jennifer Broderick, Qing Xie, Hongwei Zhang, Ran He, Qin Su, Phillip D.Zamore, Guangping Gao.363Activation of the Non-Canonical NF-kB Pathway by AAV2 Vectors:Implications in Immune Response and Gene TherapyGiridhara R. Jayandharan, George Aslanidi, George Q. Perrin, Li Zhong, Angela E. Rivers,Ashley T. Martino, Roland W. Herzog, Arun Srivastava.364Multifunctional Peptide Ligands for AAV Capsid RecognitionNagesh Pulicherla, Jana L. Phillips, Aravind Asokan.365The Rous Sarcoma Virus Promoter Carried by a rAAV Vector IsResistant to DNA Methylation in Primate Muscle and LiverAdrien Léger, Magalie Penaud-Budloo, Michael L. Nickerson, Caroline Le Guiner, PhilippeMoullier, Richard O. Snyder.366The Hybrid AAV2.5 Vector Transduces Neurons Bordering the Thirdand Fourth Ventricles after Lateral Ventricular Infusion in RatsDawn E. Bowles, Chengwen Li, Joseph E. Rabinowitz, R. Jude Samulski, Thomas J.McCown.367Differential Lymphatic Transport of Chimeric and Naturally OccurringAAV StrainsJana L. Phillips, Roland Cheung, Chengwen Li, Aravind Asokan.368Optimizing Liver Transduction of the Low Seroprevalent AAV rh32.33Luk H. Vandenberghe, Ru Xiao, James M. Wilson.369Role of a Cellular Chaperone Protein, FKBP52, in Uncoating of AAV2VectorsMengxin Li, Giridhara R. Jayandharan, Baozheng Li, Chen Ling, Wenqin Ma, ArunSrivastava, Li Zhong.370Strategies To Achieve Enhanced Transduction of Primary HumanDendritic Cells by AAV2 Vectors and Reduced Cytotoxic T CellResponse to Viral Capsids and Transgene ProductsGeorge Aslanidi, George Q. Perrin, Giridhara R. Jayandharan, Angela E. Rivers, Li Zhong,Arun Srivastava.371Optimizing Capsid Composition for the Production of RecombinantAdeno-Associated Virus Using the Baculovirus Expression SystemKirsten Erger, David Markusic, Ramaz Geguchadze, Barry J. Byrne, Sergei Zolotukhin.372Genetically Re-Engineered AAV Rep78 Identifies Sequence-RestrictedInhibitory Regions Affecting Adenoviral ReplicationVarsha Sitaraman, Patrick Hearing, Steffen Mueller, Charles Ward, Dmitri Gnatenko,Steven Skiena, Eckard Wimmer, Wadie F. Bahou.373Improved and Persistent Expression with Novel AAV Serotypes forNeonatal Gene TherapyChuhong Hu, Fides D. Lay, Joseph Springer, Ronald W. Busuttil, Gerald S. Lipshutz.374Optimization of AAV Vectors for Improved Therapeutic ProteinExpression in the Canine Models for Duchenne Muscular DystrophyAlock Malik, Marilyn Mitchell, Andrew Mead, Mike Petrov, Hansell Stedman.375rAAV1 Infect Mouse Bone Marrow-Derived Dendritic Cells throughReceptors with a2,3 and a2,6 Sialic AcidsYuanqing Lu, Sihong Song.376Using AAV Vector as Carrier for Biosensor: Detecting microRNA’sActivities by Reverse Infection of AAV VectorsWenhong Tian, Xiaoyan Dong, Gang Wang, Shuping Tan, Xiaobing Wu.Friday, May 21 st

110American Society of Gene & Cell TherapyAbstract DirectoryFriday, May 21 stFriday, May 21, 2010Poster Session II— continued6:30 PM - 8:30 PMRoom: Exhibit Hall C & B-South377Clearance of Herpes Simplex Virus by Orthogonal ManufacturingProcess of Recombinant Adeno-Associated Virus (rAAV) VectorsGuo-jie Ye, David R. Knop, Darby L. Thomas, Lijun Wang, Jeffrey D. Chulay.Adenovirus and Other DNA Virus Vectors II378Production of a Novel Class of Human Polyomavirus JC Vectors UsingBaculovirus Expression SystemKirsten E. Erger, Oleg Gorbatyuk, George Aslanidi, Ramaz Geguchadze, Barry J. Byrne,Sergei Zolotukhin.379Induction of Cell Surface Integrins in Lymphomas and PotentialApplications to Gene TherapyAnn Marie O’Neill, Farruk M. L. Kabir, David T. Curiel, Laura Timares, Bruce F. Smith.380FX-Binding Ablated Ad5 Do Not Transduce Hepatocytes but ExhibitSplenic Uptake at High DosesRaul Alba, Angela C. Bradshaw, Robert A. McDonald, Lynda Coughlan, Alan L. Parker,Ashley M. Miller, Nico van Rooijen, Stuart A. Nicklin, Andrew H. Baker.381Targeting Adenovirus Cell Entry Via Tumor-Associated EphA2 byInsertion of a Ligand Peptide into Different Loops of the Short Fiberof Ad41Michael Behr, Dirk M. Nettelbeck.382Induction of a Prostate Specific Promoter and Replication Kinetics byp21/Waf-1 shRNA Armed CRAdNaser Uddin Hoti, Sadaf Mustafa, Wasim Chowdhury, Ronald Rodriguez.383Capacitance-Based Real Time Monitoring of Virus TransductionJoung-Woo Choi.384Inhibition of PD-1 Greatly Augments Therapeutic Effect of SuicideGene Therapy for Gastrointestinal CancersHae-hyun Seo, Mi-Hyang Lee, In-Hoo Kim, Seong-Phil Shin, Kyung-Hee Chun, Sang-JinLee.385Method for Fast and Easy Adoption of First-Generation AdenoviralVectors to High-Capacity Adenoviral VectorsMartin A. Hausl, Christina Rauschhuber, Richard Voigtlander, Zsolt Ruzsics, Anja Ehrhardt.386PAUF Targeting RNA-Based Gene TherapySue Kyung Kim, Eun Ok Kim, Hyun Mi Dae, Ju Young Moon, Kyun Heo, In-Hoo Kim,Yun-Hee Kim.387Combining Oncolytic Adenoviruses and Antibody TherapyDominik E. Dorer, Roland Kontermann, Dirk M. Nettelbeck.388Direct Injection of HDAd into the Liver Is as Effective but Less ToxicThan Intravenous Injection for Crigler-Najjar Syndrome Gene TherapyFranesco Vetrini, Nathan Grove, Donna Palmer, Philip Ng, Nicola Brunetti-Pierri.389Dual-Expression Adenoviral Vectors as Vaccine CarriersXiangyang Zhou, Heng Chen, Dongming Zhou, Ang Bian, Hildegund C. Ertl.390Optimized Adenovirus Targeting through Virus-Displayed PeptideLibrary Screening in a Prostate Cancer ModelPing Wu, Tarana A. Kudrolli, Wasim H. Chowdhury, Minzhi M. Liu, Ronald Rodriguez,Shawn E. Lupold.391Human Adenovirus Type 40 Vector Engineering for Intestinal MucosaTargetingSatoshi Yamasaki, Eric Brown, Julia Davydova, Selwyn M. Vickers, Masato Yamamoto.Chemical and Molecular Conjugates II392Macropinocytosis Is the Major Pathway Leading to Transfection for aCharge-Reversal AmphiphileXiao-Xiang Zhang, Phil Allen, Mark W. Grinstaff.393Ornithine-Based Cationic Lipids: Highly Charged DendriticHeadgroups, New Lipoplex Phases and Degradable LipidsKai K. Ewert, Alexandra Zidovska, Rahau S. Shirazi, Joel Quispe, Bridget Carragher,Clinton S. Potter, Cyrus R. Safinya.394Nanoparticle-Mediated Delivery of Genes and Imaging Agents to theBrainStephen L. Hart, Alison Bienemann, Steven Gill, Panos Kyrtatos, Andrew S. Lowe, MarkLythgoe, Edward A. White, Michele J. Writer.395In Vitro and In Vivo Transfection Efficiency of DNA NanoparticlesMade with Histidinylated lPEI and Plasmid DNA Containing NFkBDNA Binding SequencePatrick Midoux, Gilles Breuzard, Ludivine Billiet, Emilie Bertrand, Tony Le Gall, TristanMontier, Pierre Lehn, Hervé Chéradame, Chantal Pichon, Philippe Guégan.EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010111Abstract DirectoryFriday, May 21, 2010Poster Session II— continued6:30 PM - 8:30 PMRoom: Exhibit Hall C & B-SouthChemical and Molecular Conjugates II396Intracellular Trafficking and Decondensation Kinetics of ChitosanpDNAPolyplexesMarc Thibault, Surendra Nimesh, Lavertu Marc, Buschmann Michael.397Dual Function Effect on PEI-Mediated Gene Delivery by DiphtheriaToxin-Derived Ligand and Fusogenic DomainsTakeshi Nagasaki, Shinji Kakimoto, Hideki Azuma.398Tumour Therapy with Listeria Monocytogenes Vector-Mediated DNADeliveryJan P. Van Pijkeren, David Morrissey, Michelle Cronin, Simon Rajendran, Gerald C.O’Sullivan, Cormac G. M. Gahan, Mark Tangney.399Efficient Gene Transfer to Umbilical Cord Blood-Derived MesenchymalStem Cells Mediated by MR Imageable Inorganic-Organic HybridConjugateYong Sook Kim, In-Kyu Park, Jin Sook Kwon, Myung Ho Jeong, Youngkeun Ahn.400Histidine-Rich Amphipathic Peptides Promote Efficient Delivery ofNucleic Acids into Mammalian CellsAntoine Kichler, A. James Mason, Christian Leborgne, Daniel Scherman, BurkhardBechinger.401MHC Class-I Mediated Antigen Presentation by a Non-Viral T-MENDVector Expressing a High Luciferase Activity in Murine DerivedDendritic Cells (JAWS-II)Sharif M. Shaheen, Hidetaka Akita, Takashi Nakamura, Shiroh Futaki, Atsushi Yamashita,Ryo Katoono, Nobuhiko Yui, Hideyoshi Harashima.402Evaluation of Polymer-DNA Nanoparticles for Gene Transfer toCardiac MusclesXiaohong Qiu, Lepeng Zeng, Jon Urban, Alena Nikolskaya, Sarah Audet.403Chemical Manipulation of AAV Tissue TropismEric D. Horowitz, Jana L. Phillips, Aravind Asokan.404Versatile Self-Assembling Nanoparticles for Enhanced siRNA Deliveryinto Mammalian CellsGulam H. Dar, Madhusudhana R. Nalam, Vijaya Gopal.405Novel L-Lysine Reducible Copolymers for Efficient Nonviral GeneDeliveryMohamed M. Ismail Nounou, Samuel Chung, Kalyopy Emmanouil, Thu Pham, ZhuoyuanLu, Malavosklish Bikram.406JL1-Directed Small Interfering RNA Delivery Using Anti-JL1 Immuno-Sendai Viroplexes to T-Leukemic CellsJung Seok Kim, Yeon Jyung Lee, Jin Ee Baek, Sang Il Park, Hwa Yeon Jeong, HongSung Kim, Keun Sik Kim, Sang Soon Yoon, Kyeong Cheon Jung, Hyung Geun Song,Yong Serk Park.407Antibody-Directed Drug Delivery Using Protein A-Based CarriersNahyun Kim, Hong-Seok Ban, Priti Kumar, Sang-Kyung Lee.Genetic and Metabolic Diseases Gene & Cell Therapy II408Lentiviral Vector-Transduced Hematopoietic Stem Cell Gene Therapyfor CystinosisBrian A. Yeagy, Frank Harrison, Matthew V. Tadlock, Daniel R. Salomon, StephanieCherqui.409Creation and Rescue of a Severe Hyperammonaemic Phenotype inOrnithine Transcarbamylase Deficient spf ash Mice Using rAAV andshRNASharon C. Cunningham, Cindy Y. Kok, Allison P. Dane, Kevin H. Carpenter, Ian E.Alexander.410Long Term Correction of Biochemical and Neurological Abnormalitiesof Metachromatic Leukodystrophy Model Mice by Systemic NeonatalInjection of Serotype 9 AAV VectorNoriko Miyake, Koichi Miyake, Nagisa Asakawa, Motoko Yamamoto, Takashi Shimada.411Neural Stem Cells as a Therapeutic for Krabbe’s DiseaseMette Flaat, Cynthia Ripoll, Jimin Yu, Jessica Eiermann, Jeanne Fisher-Perkins, BrittniScruggs, Helen Paige Leonard, Amy Lin, Marjorie McCants, Michelle Eagle, WilliamWimley, Bruce A. Bunnell.412AAV8 Mediated Expression of LDLR AmelioratesHypercholesterolemia and Regresses Pre-Existing Atherosclerosis ina Humanized Mouse Model of Familial HypercholesterolemiaSadik H. Kassim, Luk H. Vandenberghe, Christian Hinderer, Dawn Marchadier, PeterL. Bell, Hui Li, Debra Cromley, Aisha Wilson, Hongwei Yu, James M. Wilson, Daniel J.Rader.413Widespread Enzymatic Correction of CNS Tissues by a SingleIntracerebral Injection of Therapeutic Lentiviral Vector inLeukodystrophy Mouse ModelsAnnalisa Lattanzi, Claudio Maderna, Margherita Neri, Ilaria Di Girolamo, Sabata Martino,Aldo Orlacchio, Mario Amendola, Luigi Naldini, Angela Gritti.Friday, May 21 st

112American Society of Gene & Cell TherapyAbstract DirectoryFriday, May 21 stFriday, May 21, 2010Poster Session II— continued6:30 PM - 8:30 PMRoom: Exhibit Hall C & B-SouthGenetic and Metabolic Diseases Gene & Cell Therapy II414Gene Therapy Ex Vivo in the ADA-Deficient Mouse: IncreasedSurvival and Efficacy with Short-Term Enzyme Replacement TherapyPost Gene TherapyDenise A. Carbonaro, Xiangyang Jin, Donald B. Kohn.415Towards Targeted Transgene Integration in Human Hematopoietic andInduced Pluripotent Stem CellsHongjie Wang, Ying Liu, Michael C. Holmes, Philip D. Gregory, Andre Lieber.416Optimization of the Expression Cassette Using an AAV2/8 BasedVector for the Treatment of Ornithine Transcarbamylase DeficiencyLili Wang, Huan Wang, Hiroki Morizono, Peter L. Bell, David Jones, Mark L. Batshaw,James M. Wilson.417Generation of Early AMD Mouse Model by Induction of OxidativeStressSoojung Gibson, Jian W. Liu, Yun Le, Wiliam W. Hauswirth, Alfred S. Lewin.418Increased Expression of Human Glucocerebrosidase Activity in BoneMarrow of Gaucher Mice Following Macrophage Mediated GeneTherapyArlene T. Lim, Edward I Ginns.419Cell Sheet Engineering toward Bioengineering of Functional Neo-IsletsTakahiro Saito, Kazuo Ohashi, Hirofumi Shimizu, Rie Utoh, Kazuya Ise, MasayukiYamato, Teruo Okano, Mitsukazu Gotoh.420Liver-Specific Over-Expression of PGC-1a Does Not Induce a DiabeticPhenotypeLuke Roode, Chunping Qiao, Ruhang Tang, Jiangjang Jiang, Juan Li, Xiao Xiao.421Promoter Selection for AAV Vector-Mediated Factor IX Expression inSkeletal MuscleAkihiro Kume, Hiroya Yagi, Hiroaki Mizukami, Masashi Urabe, Tomonori Tsukahara, AkiraIshiwata, Jun Mimuro, Seiji Madoiwa, Tsukasa Ohmori, Yoichi Sakata, Keiya Ozawa.422Development of HIV-1 Based Lentiviral Vectors Expressing Pre-Trans-Splicing Molecules (PTMs) for Liver-Directed TherapiesMadaiah Puttaraju, S. Gary Mansfield, Jun Wang, Nikolay Korokhov, Jenice D’Costa,Ziping C. Chen, Katherine Radd, Gerard J. McGarrity, Laurent M. Humeau.764 (Moved from Poster Session III)Microporous Polymer Scaffolds for Islet TransplantationRomie F. Gibly, Lonnie D. Shea.Cardiovascular Gene & Cell Therapy423AAV-Mediated Intramyocardial VEGF-B167 Expression Exerts aPotent Cardioprotective Effect in Small and Large Animal Models ofMyocardial Infarction and Heart FailureLorena Zentilin, Vincenzo Lionetti, Uday Puligadda, Silvia Moimas, Serena Zacchigna,Martino Pepe, Mohammed Mamdani, Khaled Qanud, Xiabin Xu, Thomas H. Hintze,Fabio A. Recchia, Mauro Giacca.424Osteopontin Enhances the Angiogenic Potential of EndothelialProgenitor CellsErin E. Vaughan, Angela Duffy, Timothy O’Brien.425Arginine and Tetrahydrobiopterin Synergistically Potentiate theAntirestenotic Effect of Vascular Gene Therapy with Inducible NitricOxide SynthaseIlia Fishbein, Peter Sobolewki, Richard F. Adamo, Ivan S. Alferiev, Ariel Fishbein, MarinaBakay, Michael Chorny, Robert J. Levy.426Intra-Myocardial Administration of ACRX-100 Promotes CardiacBenefit and Improves Angiogenesis in a Porcine Model of HeartFailureJoseph M. Pastore, Timothy J. Miller, Rahul A. Aras, Marc S. Penn.427Strategies for Promoting Survival of Transplanted Mesenchymal StemCells in a Myocardial Infarction ModelLisa McGinley, Daniel O’Toole, Aoife Duffy, Xizhe Chen, Alessia Stocca, Jill McMahon,Timothy O’Brien.428Systemic Delivery of Interleukin-10 by an AAV Vector AttenuatesObesity-Related Glomerulopathy in Zucker Fatty RatsManabu Ogura, Masashi Urabe, Akira Onishi, Takayuki Ito, Tomonori Tsukahara, HiroakiMizukami, Akihiro Kume, Eiji Kusano, Keiya Ozawa.429AAV/B7H1-Gene Delivery Lowers Th1 Cytotoxic T LymphocyteResponse In Vitro and Atherogenesis In VivoMaohua Cao, Junaid A. Khan, Yong Liu, Paul L. Hermonat.430Dose-Dependent Angiogenesis by Human and Murine VEGF IsSpecies-SpecificEdin Mujagic, Roberto Gianni-Barrera, Marianna Trani, Lorenz Gürke, Michael Heberer,Thomas Wolff, Andrea Banfi.431AAV-Sema3A-Mediated Recruitment of Neuropilin-1-ExpressingMononuclear Cells (NEMs) Contributes to Vessel Stabilization andNormalizationAlessandro Carrer, Serena Zacchigna, Silvia Moimas, Lucia Pattarini, Lorena Zentilin,Mauro Giacca.EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010113Abstract DirectoryFriday, May 21, 2010Poster Session II— continued6:30 PM - 8:30 PMRoom: Exhibit Hall C & B-SouthCardiovascular Gene & Cell Therapy432Identification of AAV6 as Most Efficient Vector for TransvascularGene Transfer into Porcine Myocardium Based on an In Vitro Modelfor Prediction of the Cardiac Gene Transfer PerformanceJan Ksienzyk, Philip W. Raake, Philipp Schlegel, Changguang Shan, Christophe Weber,Jürgen A. Kleinschmidt, Hugo A. Katus, Oliver J. Müller.433Percutaneous Transendocardial Adminstration of AAV6 and AAV8Vectors to Rhesus Macaques Results in Highly Efficient and GlobalCardiac Gene TransferGuangping Gao, Meg M. Sleeper, Lawrence Bish, Lan Sun, You Lu, Jiachuan Duan,Chunyan Hu, Li Wang, H. Lee Sweeney.434Gene Transfer of VEGF165, HGF, Urokinase and Their CombinationsUsing Novel PC4W Plasmid for Induction of Vasculogenesis in MiceHind Limb Ischemia ModelPavel Makarevich, Zoya Tsokolaeva, Alexander Shevelev, Igor Rybalkin, EugeniyShevchenko, Irina Beloglazova, Tatyana Vlasik, Elena Parfyonova, Vsevolod A. Tkachuk.435PEGylation of Helper-Dependent Adenoviral Vector-MediatedLong-Term Expression of Human Apolipoprotein A-I ReducesAtherosclerosis in LDLR Deficient MiceEleonora Leggiero, Dalila Astone, Piyanuch Wonganan, Cristina Mazzaccara, GiuseppeLabruna, Luciana Sacchetti, Francesco Salvatore, Maria Croyle, Lucio Pastore.436AAV/IL13-Gene Delivery Lowers Atherogenesis in LDLR KO MiceJunaid A. Khan, Maohua Cao, Yong Liu, Paul L. Hermonat.437AAV/hSTAT3-Gene Delivery Lowers Atherosclerosis in LDLR KO Miceon High Cholesterol DietJunaid A. Khan, Maohua Cao, Bum-Yong Kang, Jawahar L. Mehta, Paul L. Hermonat.438Intramuscular Delivery of ACRX-100 Enhances Angiogenesis inRabbits with Hind Limb IschemiaTimothy J. Miller, Joseph M. Pastore, Rahul A. Aras, Marc S. Penn.439A Comparison of Three Liposomal Formulations for Gene Deliveryfrom Coronary Artery StentsSandra Ganly, Sean O. Hynes, Faisal Sharif, Karl McCullagh, Valerie Barron, Jim Crowley,Peter McHugh, Timothy O’Brien, Udo Greiser.440Efficient and Localized Gene Transference in Rat Heart byElectroporationLeonardo P. Carvalho, Eduardo G. Yasumura, Vivian Somoto, Priscila M. A. Denapoli,Flavia H. Silva, Valderez B. Valero, Hans F. Dohmann, Christina M. Takiya, Sang W. Han.Ophthalmic Disorders and Technological Advances441Gene Delivery of Erythropoietin Protects Retinal Ganglion Cells inDBA/2J Glaucomatous MiceTimothy A. Sullivan, Eldon E. Geisert, Tonia S. Rex.442Pan-Retinal Secretion of GDNF Following Intravitreal Transduction ofMüller Glia Slows Photoreceptor Loss in Retinal DegenerationDeniz Dalkara, Kathleen D. Kolstad, Meike Visel, Ryan R. Klimczak, Karen Guerin, DavidV. Schaffer, John G. Flannery.443AAV-Mediated Gene Supply of Non-Erythropoietic ErythropoietinDerivatives Improves Photoreceptor Morphology and Function inModels of Retinal Degenerative DiseasesPasqualina Colella, Carolina Iodice, Umberto Di Vicino, Alberto Auricchio.444Early Indicators of Biological Efficacy in a Phase 1/2 Gene TherapyTrial for Leber Congenital Amaurosis (LCA)Shalesh Kaushal, Margaret Humphries, Elena Filippova, George Asdourian, RadouilTzekov, Michael Stalvey, Terrence Flotte.445Positive Responses in a Mouse Model of Leber Congenital Amaurosisafter Treatment with Compacted DNA NanoparticlesKiichiro Okano, Tadao Maeda, Linas Padegimas, Tomasz H. Kowalczyk, Sharon M.Oette, Christopher R. Gedeon, Ozge Sesenoglu-Laird, Susannah L. Hyatt, Karla A. Dines,Elena Tyr, Nikia L. Beal, Robert C. Moen, Krzysztof Palczewski, Mark J. Cooper.446Adeno-Associated Virus Mediated Gene Therapy with a RhodopsinRibozyme for Treatment of Autosomal Dominant Retinitis Pigmentosa(Adrp)Haoyu Mao, Marina S. Gorbatyuk, William W. Hauswirth, Alfred S. Lewin.447POD DNA Nanoparticles Rescue an Adult Mouse Model of RetinalDegenerationSarah P. Read, Siobhan M. Cashman, Rajendra Kumar-Singh.448Protection Against Laser-Induced Choroidal NeovascularizationFollowing Delivery of an Adenovirus Expressing a Soluble Form ofHuman CD59 to Murine RetinaSiobhan M. Cashman, Kasmir Ramo, Rajendra Kumar-Singh.449Dose Finding Study in Galactosialidosis Mice Using scAAV2/8-LP1-ppca VirusHuimin Hu, Elida Gomero, Eric Bonten, John Gray, Christopher Calabrese, Arthur Nienhuis,Alessandra d’Azzo.Friday, May 21 st

114American Society of Gene & Cell TherapyAbstract DirectoryFriday, May 21 stFriday, May 21, 2010Poster Session II— continued6:30 PM - 8:30 PMRoom: Exhibit Hall C & B-SouthOphthalmic Disorders and Technological Advances450Characterization of 12 AAV Vectors for Intravascular Delivery ToTarget CNS and Detarget Non-CNS Tissues by miRNA Regulation:Implications in Treatment of Canavan DiseaseHongwei Zhang, Bin Yang, Jun Xie, Qing Xie, Qin Su, Ran He, Miguel Sena-Esteves,Zuoshang Xu, Guangping Gao.451Efficient Expression of Smn from Integration-Deficient LentiviralVectorsSherif O. Ahmed, Hugo Peluffo, Edmund Foster, Natalia Lago, Lawrence Moon, ThomasHutson, Ping Yip, Klaus Wanisch, Stephen B. McMahon, Rafael J. Yáñez-Muñoz.452Efficacy of an Adenovirus Vector/Cocaine Conjugate-Based Anti-Cocaine Vaccine in Shielding the Brain from Systemically AdministeredCocaineMartin J. Hicks, Bishnu P. De, Jonathan B. Rosenberg, Jesse T. Davidson, Amira Y.Moreno, Kim D. Janda, Neil R. Hackett, Stephen M. Kaminsky, Stefan Worgall, RonaldG. Crystal.453Genetically Engineered Suppressor Cells Target CNS and InhibitActivated Effector T-CellsMoa Fransson, Elena Piras, Hao Wang, Ida Rasmusson, Katarina LeBlanc, Eva Brittebo,Angelica S. I. Loskog.Musculo-skeletal Gene & Cell Therapy II454First Generation AAVmicroutrophin Vector Infused into the IsolatedPelvic Limb of a Canine Model for Duchenne Muscular DystrophyMihail Petrov, Marilyn Mitchell, Alock Malik, Andy Mead, Frederick Balzer, Leonard Su,Jacqueline Farag, Benjamin Kozyak, Kapil Gopal, Charles Bridges, Janet Bogan, MartinChilders, Joe Kornegay, Hansell Stedman.455Characterization of A20 as an Inhibitor of NF-kB Activation inDystrophic MiceRakshita Charan, Paula R. Clemens.456Plasticity of Skeletal Muscle Cells during Muscle Injury and Repair –A Dedifferentiation StudyXiaodong Mu, Hairong Peng, Johnny Huard, Yong Li.457Increased Muscle Regeneration in Hindlimb and Diaphragm of mdxMice Treated with AAV9 Mini-Dystrophin and Octalysine-NEMOBinding Domain PeptideDaniel P. Reay, Geno Raggi, Bing Wang, Xiao Xiao, Paul D. Robbins, Paula R. Clemens.458External, Non-Invasive Monitoring of Progressive CardiorespiratoryDysfunction in a Canine Model of DMDAndrew Mead, Alock Malik, Mihail Petrov, Martin Childers, Janet Bogan, JosephKornegay, Hansell Stedman.459The Polyproline Site in Hinge 2 Influences the Functional Capacity ofTruncated DystrophinsGlen B. Banks, Luke M. Judge, James M. Allen, Jeffrey S. Chamberlain.460Combining Gene and Stem Cell Therapy in the Treatment ofDysferlinophatiesDaniele Parolini, Claire Navarro, Andrea Farini, Mirella Meregalli, Marzia Belicchi, PaolaRazini, M. Krahn, Louis Garcia, Nicolas Lévis, Yvan Torrente.461Deletion of Functional Domains of Dp116 Leads to AlteredSarcolemmal Expression and Subcellular Localization When Expressedin Skeletal MuscleAndrea L. Arnett, Guy L. Odom, Kristy Boyle, Eric Finn, Jeffrey S. Chamberlain.462A New Therapeutic Approach for Duchenne Muscular Dystrophy:Restoration of the Dystrophin Reading Frame with a MeganucleaseJacques P. Tremblay, Pierre Chapdelaine, Christophe Pichavant, Joel Rousseau, FrédéricPâques.463Regulatory Cassettes Derived from the Slow Troponin I GeneConfer High-Level Expression in Skeletal Muscle after Gene TransferMediated by Helper-Dependent Adenovirus and Recombinant AAVRénald Gilbert, Mehdi Bendjelloul, Yué Zeng, Claude Guérin, Nancy Larochelle, GeorgeKarpati, Bernard Massie, Josephine Nalbantoglu.464Cell Therapy of Muscular Dystrophy with Engineered Cd133+ CellsAndrea Farini, Mirella Meregalli, Daniele Parolini, Marzia Belicchi, Simona Maciotta,Paola Razini, Joao da Silva Bizario, Luis Garcia, Nereo Bresolin, Yvan Torrente.465Improved Regenerative Capacity of Adult Stem Cells Isolated fromInjured Skeletal Muscle of MouseXiaodong Mu, Ian Bellayr, Haiying Pan, Yong Li.466Sarcolemmal nNOS Anchoring Reveals a Functional Differencebetween Dystrophin and UtrophinYongping Yue, Dejia Li, Luke Judge, Akshay Bareja, Yi Lai, Kay E. Davies, Jeffrey S.Chamberlain, Dongsheng Duan.EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010115Abstract DirectoryFriday, May 21, 2010Poster Session II— continued6:30 PM - 8:30 PMRoom: Exhibit Hall C & B-SouthMusculo-skeletal Gene & Cell Therapy II467Detailed Physical Mapping of Deletion Breakpoints in the GSHP DogModel for DMDAlock Malik, Acong Xu, Jesse Chen, Andrew Mead, Martin Childers, Janet Bogan, ScottSchatzberg, Joe Kornegay, Hansell Stedman.468Lentiviral Vector Mediated Delivery of Full-Length Dystrophin forGene Therapy of Muscular DystrophyEn Kimura, Katsuhisa Uchio, Tomohiro Suga, tatsuya Koide, Yuji Uchida, Yasushi Maeda,Satoshi Yamoshita, Jeffrey S. Chamberlain, Makoto Uchino.Cancer – Immunotherapy II469Elimination of Cancer Stem Cells with Genetically Engineered T CellsExpressing a Stage Specific Embryonic Antigen-1 (SSEA1) ChimericAntigen ReceptorAntonina V. Kurtova, Juan Vera, An Lu, Adham Bear, Aaron E. Foster.470Targeting Cancer Stem Cells in OsteosarcomaAlexia Ghazi, Nino Rainusso, Vita Salsman, Helen Heslop, Steven Gottschalk, NabilAhmed.471CMV-Specific HER2-Redirected T Cells for the AdoptiveImmunotherapy of GlioblastomaAlexia Ghazi, Vita Salsman, Yvonne Kew, Donald Shaffer, Suzanne Powell, RobertGrossman, Michael Scheurer, Ann Leen, Catherine Bollard, Helen Heslop, StephenGottschalk, Nabil Ahmed.472Combining mTor Inhibitors with Rapamycin-Resistant T Cells: A Two-Pronged Approach to Tumor EliminationLeslie E. Huye, Barbara Savoldo, Gianpietro Dotti, Matthew H. Wilson, Cliona M. Rooney.473Evaluating the Combination of 5’Azacytidine and MAGE-A4-SpecificT Cell Therapy as a Potential Immunotherapeutic Strategy forRefractory Hodgkin’s LymphomaConrad R. Cruz, Ulrike Gerdemann, Jessica A. Shafer, Ann M. Leen, Tamara Tripic, TerzahM. Horton, Anas Younes, Cliona M. Rooney, Helen E. Heslop, Catherine M. Bollard.474The iCD40.MyD88 Dendritic Cell (DC) Gene Switch Leads to PotentAnti-Tumor TherapyNatalia Lapteva, Priyadharshini Narayanan, Mamatha Seethammagari, Kevin M. Slawin,David M. Spencer.475Emozolomide Inhibits the Migration of Immune Cells into the BrainTumor Microenvironment and Their Systemic Expansion, but Exertsa Synergistic Anti-Tumor Effect When Combined with CombinedConditional Cytotoxic/Immune-Gene TherapyMaria G. Castro, Marianela Candolfi, Kader Yagiz, Kurt M. Kroeger, David Foulad,Garbielle Ahlzadeh, Matthew Tesarfreund, Pedro R. Lowenstein.476TCR Engineered and In Vitro Expanded T Lymphocytes Recapitulatethe Properties of Central Memory T CellsShicheng Yang, Zhili Zheng, Ling Zhang, Steven A. Rosenberg, Richard A. Morgan.477Phase I Safety and Immunogenicity of HPV 16 and 18 DNA VaccinesDelivered Via ElectroporationJian Yan, Panyupa Pankhong, Xuefei Shen, Mary Giffear, Jessica Lee, Drea Harris,Deanna Diaz, Amir Khan, Mark Bagarazzi, Jean Boyer, David B. Weiner, Niranjan Y.Sardesai.478Improving Adoptive T Cell Therapy by Transduction of TIL with aVector That Mediates the Inducible Expression of IL-12 in the TumorMicroenvironmentLing Zhang, Sid P. Kerkard, Shicheng Yang, Zhili Zheng, Zhiya Yu, Nichaolas P. Restifo,Steven A. Rosenberg, Richard A. Morgan.479Robust and Sustained Ex Vivo Expansion of NK Cells with ArtificialAPCs Bearing Membrane-Bound IL-21 Is Associated with a DistinctPhenotype and Transcriptional ProfileCecele J. Denman, Vladimir Senyukov, Lisa M. Kopp, Maria Lima de Silva, Harjeet Singh,Lenka Hurton, Simon Olivares, Sourindra Maiti, Mary H. Huls, Richard E. Champlin,Laurence J. N. Cooper, Dean A. Lee.480STAT3-Inactivated Dendritic Cell Vaccination Could Induce StrongerAnti-Tumor Immune ResponsesHidetoshi Sumimoto, Tomoko Iwata-Kajihara, Hiroyuki Mizuguchi, Kiyoshi Takeda,Yutaka Kawakami.481Combination Therapy for Melanoma Using Virotherapy and AlternateTLR Stimulating AgonistsRosa Diaz, Marta Compte-Grau, Elizabeth Ilett, Phonphimon Wongthida, Feorillo Galivo,Timothy Kottke, Jill Thompson, Alan Melcher, Richard Vile.482Bid Is a Key Factor for Eliciting the Antiproliferative Activity of IFN-aMediated by TRAILTakaya Tsuno, Josef Mejido, Tongmao Zhao, Terry Phillips, Kathryn Zoon.483Oral Adeno-Associated Virus-neu (AAV-neu) Immunotherapy Inhibitsthe Growth of neu+ Murine Breast CancerJason C. Steel, Giovanni Di Pasquale, Charmaine A. Ramlogan, Caroline Morris, John A.Chiorini, John C. Morris.Friday, May 21 st

116American Society of Gene & Cell TherapyAbstract DirectoryFriday, May 21 stFriday, May 21, 2010Poster Session II— continued6:30 PM - 8:30 PMRoom: Exhibit Hall C & B-SouthCancer – Immunotherapy II484Tumor-Specific Antitumor Activity of mIL-10 Revealed byHydrodynamic Tail Vein Injection of pCMV-mIL Plasmids in Tumor-Bearing MiceJianfeng Li, Li Hai, Shulin Li, Dexi Liu.485Liver Specific, Inducible, AAV-Mediated IL12 Delivered Resulted ina Strong Anti Tumoral Inmune Response in a Murine Model of LiverMetastasisLucia Vanrell, Laura Blanco, Pedro Berraondo, Marianna Di Scala, Astrid Paneda, VictorBaldim, Jesus Prieto, Gloria González-Aseguinolaza.486AdCD40L Gene Therapy Enhances the Efficacy of Chemotherapy inExperimental Bladder CancerLina S. E. Liljenfeldt, Lisa H. Christiansson, Katerina Gkirtzimanaki, Angelica S. I. Loskog,Aristides G. Eliopoulos.487Xenograft Expanded FANG Autologous Tumor Cell VaccineDevelopment and Manufacturing for Clinical UsePhillip B. Maples, Padmasini Kumar, Yang Yu, Beena O. Pappen, David Monsma,Stephanie Scott, Dawna Dylewski, Craig Webb, Neil Senzer, John Nemunaitis.Cancer-Oncolytic Viruses II488Optimization of Measles Virus Infected Mesenchymal Stem CellCarriers for Clinical Testing in Patients with Recurrent Ovarian CancerKah-Whye Peng, Emily K. Mader, Greg Butler, Marla Sommerfield, Sean C. Dowdy, AllanB. Dietz.489Expression of Interferon Alpha from an Oncolytic Adenovirus VectorDecreases Toxicity but Retains the Anti-Tumor Efficacy of the VectorJacqueline F. Spencer, Debanjan Dhar, Elena V. Shashkova, Karoly Toth, William S. M.Wold.490Measles Virus Encoding H. pylori Neutrophil-Activating Protein forTreatment of Metastatic Breast CancerIanko D. Iankov, Cory Allen, Stephen J. Russell, Mark J. Federspiel, Evanthia Galanis.491Carrier Cells Delivery of Inducible Oncolytic Adenovurs for BrainTumorHiroshi Nakashima, E. A. Chiocca.492Optimizing the Genomic Stability, Transgene Expression, andTherapeutic Efficacy of Replication-Competent Retrovirus Vectors forProdrug Activator Gene TransferKei Hiraoka, Logg R. Christopher, Akihito Inagaki, Hiroshi Matsumoto, Oscar Diago,Omar Perez, Joan Robbins, Harry Gruber, Douglas Jolly, Noriyuki Kasahara.493Gene Therapy for Head and Neck Squamous Carcinoma Cells byIAI.3B Promoter-Driven Oncolytic Adenovirus-Infected Carrier CellsKatsuyuki Hamada, Ting Zhang, Koh-ichi Nakashiro, Hiroyuki Hamakawa.494Evaluation of Monocytes and Cancer Cells as Carriers for OncolyticAdenoviruses in Immune-Competent Models of Pancreatic Cancer inSyrian HamstersEva Garcia-Aragoncillo, Sergia Bortolanza, Maria Buñuales, Jesus Prieto, RubenHernandez-Alcoceba.495Combination Therapy for Breast Cancer Using Oncolytic Viruses andHistone Deacetylase InhibitorsHongxun Wang, Stephen J. Russell, Jian Qiao.496Combination Oncolytic VirotherapyTimothy Kottke, Jill Thompson, Konstantin Doronin, Sonia Guedan Carrio, William Wold,Ramon Alemany, Richard Vile.497Conditionally Replicative Adenovirus with an Adenoviral Major LatePromoter-Driven Imaging Cassette Predicts In Vivo Anti-Tumor EffectJulia Davydova, Tatyana Gavrikova, Eric J. Brown, Xianghua Luo, David T. Curiel, SelwynM. Vickers, Masato Yamamoto.498Susceptibility of Neuroblastoma Primary Tumor-Initiating Cells toOncolytic Herpes Simplex Virus Is Determined by Nectin-1 ExpressionPin-Yi Wang, Mark A. Currier, Margaret H. Collins, Betsy A. DiPasquale, Loen Hansford,David Kaplan, Sean Lawler, E. Antonio Chiocca, Timothy P. Cripe.499Activity of Oncolytic Measles Virus Strains Against Brain Tumor StemCellsCory Allen, Mark A. Schroeder, Jann N. Sarkaria, Mark J. Federspiel, Stephen J. Russell,Evanthia Galanis.500Replication-Competent Retrovirus Vector-Mediated Suicide GeneTherapy Achieves Significant Therapeutic Efficacy Against HumanMalignant Mesothelioma XenograftsYoshiko Kawasaki, Norie Yamaoka, Nobuyuki Terada, Haruki Okamura, NoriyukiKasahara, Shuji Kubo.501Oncolytic Adenovirus with Somatostatin Motif for Selective Infectionof Neuroendocrine TumorsDi Yu, Justyna Leja, Berith Nilsson, Magnus Essand.EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010117Abstract DirectoryFriday, May 21, 2010Poster Session II — continued6:30 PM - 8:30 PMRoom: Exhibit Hall C & B-SouthCancer-Oncolytic Viruses II502Silencing a p53 Inhibitor in Cancer Cells Increases Killing Potency ofOncolytic AdenovirusChristie Vermeulen, Nikki Tol, Winald R. Gerritsen, Victor W. van Beusechem.503Safety of Intravenous Ad5-Mda-7, a Potential Anti-Metastatic Agentin Gynecologic CancerKenneth H. Kim, Meredith A. Preuss, Minghui Wang, Anand C. Annan, Justin A. Barnes,Devanand Sarkar, Steven Grant, Paul Dent, Paul B. Fisher, Ronald D. Alvarez, David T.Curiel.504Characterization of a Novel Dual-Lock Oncolytic Cadvex-VectorThat Combines Efficient Prostate-Specific Replication with CytokineExpressionBrian D. Hoel, Min Luo, David A. Einfeld, Danher Wang, John Y. Dong.505A Probasin Promoter, Conditionally Replicating Adenovirus thatExpresses the Sodium Iodide Symporter (NIS) for Radiovirotherapyof Prostate CancerMiguel A. Trujillo, Michael J. Oneal, Samantha McDonough, Rui Qin, John C. Morris.506Adenovirus Vectors Transductionally Retargeted to Her2/neu forProstate Tumour TreatmentMaria K. Magnusson, Robert Kraaij, Corrina M. A. De Ridder, Leif Lindholm.Cancer-Targeted Gene & Cell Therapy II507The Potential of Conditionally Replicating Adenovirus ExpressingTIMP2 for Ovarian Cancer TherapySherry W. Yang, James J. Cody, Joanne T. Douglas, Ronald D. Alvarez, SelvaranganPonnazhagan.508Mechanisms of the Tmpk/AZT-System Bystander Effect; Cell FateControl Gene Therapy for Anti-Cancer TreatmentTakeya Sato, Anton Neschadim, Jun Sukegawa, Teruyuki Yanagisawa, Jeffrey A. Medin.509Truncated CD19 Fused with Mutant Human Tmpk: A Versatile CellFate Control Safety CassetteMatthew D. Scaife, Sean P. Devine, Anton Neschadim, Natalia A. Pacienza, Daniel H.Fowler, Jeffrey A. Medin.510Muscle Directed Systemic Cancer Gene Therapy for Lymphoma UsingType 8 AAV Vector Expressing mda-7/IL24Nanya Wang, Bai Fan, Koichi Miyake, Noriko Miyake, Takashi Shimada.511A Liposome Formulation with High Accumulation in Tumor Tissue forTargeted Delivery of Nucleic AcidTorben Gjetting, Camilla L. Christensen, Frederik Cramer, Hans S. Poulsen, Thomas L.Andresen.51215-LO-1 Induced Apoptosis Inhibits Tumour Growth and ExtendsSurvival in Rat Glioma ModelAgnieszka Pacholska, Helena Viita, Farizan Ahmad, Anna Hyvärinen, Thomas Wirth,Seppo Ylä-Herttuala.513An Efficient Targeted Gene Therapy Using Brain Tumor-SpecificPromoterToshio Yawata, Eri Ishida, Yu Kawanishi, Masakazu Tamura, Keiji Shimizu.514Nitric Oxide Synthase One Homologous Recombinant Negative(NOS1 -/-) Mice Are Protected from Thoracic Irradiation InducedSeizures by Esophageal Administration of Manganese SuperoxideDismutase Plasmid Liposome Complex (MnSOD-PL)Malolan Rajagopalan, Jean-Claude Rwigema, Brandon Stone, Michael Epperly, JulieGoff, Tracy Dixon, Darcy Franicola, Joel Greenberger.515Maternal Manganese Superoxide Dismutase Plasmid/LiposomeComplex (MnSOD-PL) Gene Therapy of E13 Pregnant Mice ReducesTotal Body Irradiation Induced Growth Retardation in Newborn MiceMichael Epperly, Tracy Dixon, Xichen Zhang, Benjamin Greenberger, Paavani Komanduri,Hong Wang, Joel Greenberger.516Adenovirus-Relaxin Gene Therapy on Keloids: AttenuatedProliferative Response and Collagen DegradationIl-Kyu Choi, Il-Kyu Lee, Yong Oock Kim, Dong Kyun Rah, Chae-Ok Yun.517Inducing Systemic Anti-Tumor Immune Responses through DirectTumor TargetingG. Campbell Kaynor, Liaomin Peng, Jorge Sanchez-Salazar, Yang-Xin Fu, XinzhongWang.518Angiotensin Type 2 Receptor Mediated Apoptosis of Human ProstateCancer CellsHongwei Li, Yanfei Qi, Chengyao Li, Leah N. Braseth, Yongxin Gao, Arseniy E. Shabashvili,Michael J. Katovich, Colin Sumners.519 Abstract Withdrawn520Regulatory Submission Process for Gene and Cellular TherapiesGladice Wallraven, Phillip B. Maples, John Nemunaitis.Friday, May 21 st

118American Society of Gene & Cell TherapyAbstract DirectoryFriday, May 21 stFriday, May 21, 2010Poster Session II — continued6:30 PM - 8:30 PMRoom: Exhibit Hall C & B-SouthHematologic and Immunologic Gene & Cell Therapy II521Lentiviruses Containing a Modified Ankyrin-1 Promoter DirectUniform, Copy-Number-Dependent Expression of a g-Globin Gene atTherapeutic LevelsFaith Harrow, Karina Laflamme, Amanda Cline, David M. Bodine.522Non-Myeloablative Conditioning Regimen To Increase Engraftment ofGene-Modified Hematopoietic Stem CellsTeiko Sumiyoshi, Chang J. Lee, Roger Hollis, Francesca Giannoni, Stan F. Louie, Alice F.Tarantal, Donald B. Kohn.523In Vivo Selection of Hematopoietic Stem Cells by Expressing aTruncated Epo Receptor (tEpoR)Maria Rosa Lidonnici, Francesca Tiboni, Giacomo Mandelli, Claudia Cattoglio, MargheritaGalletti, Alexis Grande, Fulvio Mavilio, Giuliana Ferrari.524Successful Treatment of Canine Leukocyte Adhesion Deficiency Usinga SIN Lentiviral Vector with the PGK Promoter Expressing CanineCD18Michael J. Hunter, Huifen Zhao, Laura M. Tuschong, Tanya H. Burkholder, Derek A.Persons, Dennis D. Hickstein.525Diminished End Organ Damage and Correction of Anemia in SickleCell Mice Treated with Non-Myeloablative Busulfan Conditioning andg-Globin Lentiviral Vector Transduced HSCsTamara I Pestina, Phillip W. Hargrove, Huifen Zhao, Peter Vogel, Derek A. Persons.526Small but Powerful, Predicting the Outcome of Gene Therapy TrialUsing NSG MiceTomoyasu Higashimoto, Elke Grassman, Jose A. Cancelas, Punam Malik.527Development of a Bioengineered Recombinant Factor VIII TherapeuticUsing a Lentiviral Production PlatformChristopher B. Doering, Gabriela Denning, Richard Gautney, Boro Dropulic, Lajos Baranyi,Andre J. Roy, Bagirath Gangadharan, Ernest T. Parker, Pete Lollar, H. Trent Spencer.528Transgenic Expression of Cytidine Deaminase (CDD) forMyeloprotective PurposesNico Lachmann, Nils Pfaff, Sebastian Brennig, Doreen Lüttge, Tobias Cantz, ChristopherBaum, Axel Schambach, Thomas Moritz.529Development of a Pre-Clinical Model for the Gene Therapy Treatmentof Wiskott-Aldrich Syndrome (WAS)Alexander Astrakhan, Byoung Ryu, Brigid Stirling, Blythe Sather, Jit Khim, MikhailGaribov, Stephanie Humblet-Baron, Hans Ochs, David J. Rawlings.530Lentiviral Gene Therapy of Murine Hematopoietic Stem Cells UsingCodon Optimized IL2RG cDNA: A Comparison of Multiple PromoterElements and Transplant ConditionsMarshall W. Huston, Niek P. van Til, Trudi P. Visser, Roya Sawari, Shazia Arshad, GerardWagemaker.531Human Fetal Liver HSCs Demonstrate High Transduction Rates andSustained Transgene Expression Following ImplantationNiraja Dighe, Maroun Khoury, Mark Chong, Citra Mattar, Michael N. Antoniou, JianzhuChen, Mahesh Choolani, Jerry Chan.532FANG Autologous Tumor Cell Vaccine Development and ManufacturingPhillip B. Maples, Padmasini Kumar, Yang Yu, Beena O. Pappen, Chris M. Jay, ZhaohuiWang, Donald D. Rao, Joseph Kuhn, John Nemunaitis, Neil Senzer.533Atomic Force Microscopy (AFM) Shows Lower Membrane Resistanceof Human T Cells Rendered Deficient in WASP by RNAiVéronique Pariétti, Ruthger Van Zwieten, Malgorzata Lekka, Nicolas Mermod, Anne Galy.534A Combination of Codon Optimization and Amino Acid Substitution inthe Human Factor IX Gene Yields a High Level of Superactive FactorIXThipparat Suwanmanee, William Hannah, Tong Gui, Hong Ma, Adam S. Cockrell, PaulE. Monahan, Tal Kafri.Immunologic & Host Responses in Gene & Cell Therapy535In Vivo Expansion of Regulatory T Cells with IL2-mAb ComplexesPrevents and Modulates Anti-Factor VIII Immune Responses inHemophilia A Mice after Factor VIII Plasmid-Mediated Gene TherapyChao-Lien Liu, Peiqing Ye, Benjamin Yen, Baowei Peng, Carol H. Miao.536Phase I Safety and Pharmacokinetic Study of Systemic p53 GeneTherapy (SGT-53) Using Immunolipoplexes Targeted by Anti-Transferrin Receptor (TfR) Single Chain Antibody Fragment (scFv):Updated ResultsNeil Senzer, John Nemunaitis, Cynthia Bedell, Robert Nunan, Henry Allen, Leanne Sleer,Esther Chang.537Induction of Type I Interferon (IFN) by Adenovirus-Encoded SmallRNAsTomoko Yamaguchi, Kenji Kawabata, Emi Kouyama, Takayuki Suzuki, Fuminori Sakurai,Shinnosuke Kurachi, Kazufumi Katayama, Hiroyuki Mizuguchi.EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010119Abstract DirectoryFriday, May 21, 2010Poster Session II — continued6:30 PM - 8:30 PMRoom: Exhibit Hall C & B-SouthImmunologic & Host Responses in Gene & Cell Therapy538Immunological Effects of Oral and Intravenous Cyclophosphamide inCancer Patients Treated with Oncolytic AdenovirusesVincenzo Cerullo, Sophie Escutenaire, Sari Pesonen, Iulia Diaconu, Liisa Sirrka, AnnaKanerva, Lotta Kangasniemi, Elina Haavisto, Minna Oksanen, Tiimo Joensuu, A. Karioja-Kallio, Petteri Arstila, Akseli Hemminki.539The Role of TGF-b and IL-10 in the Development of ImmuneTolerance Following Hepatic Gene TherapyBrad E. Hoffman, Ashley T. Martino, Brandon K. Sack, Roland W. Herzog.540Murine Hepatocytes Transduced with Y-F Mutant Capsid Are MoreResistant to Killing by Capsid Specific CD8+ T CellsAshley Martino, David M. Markusic, Arun Srivastava, Roland W. Herzog.541 Abstract Withdrawn542The Innate Immune Response to Intravenously Injected AdenoviralVectors: Role of Endosomal Escape in MAP Kinase Activation and theCytokine/Chemokine ResponseJeffrey S. Smith, Zhili Xu, Jie Tian, Donna J. Palmer, Philip Ng, Andrew P. Byrnes.543AAV8 Vectors Evade CTL Mediated Destruction by Failing To Activatea Potent Inflammatory ResponseSuryanarayan Somanathan, Ekaterina Breous, Peter L. Bell, James M. Wilson.544Robust and Sustained Factor IX Expression by IV Administration ofAAV8-Based Vectors in MacaquesHiroaki Mizukami, Jun Mimuro, Akira Ishiwata, Hiroya Yagi, Tsukasa Ohmori, SeijiMadoiwa, Tomonori Tsukahara, Masashi Urabe, Akihiro Kume, Yoichi Sakata, KeiyaOzawa.545Induction of Transgene Immunological Tolerance by a Single Injectionof miR-142-Regulated Integrase Defective Lentiviral VectorAndrea Annoni, Alessio Cantore, Lucia Sergi Sergi, Luigi Naldini, Maria Grazia Roncarolo.546T Cell Hyperactivity in Cmah Null Mice: A Pre-Clinical rAAVImmunotoxicity Model?George Buchlis, Federico Mingozzi, Daniel J. Hui, Harre Downey, Virginia Haurigot,Shangzhen Zhou, Ajit Varki, Katherine A. High.547Complement-Mediated Clearance of AAV by Tissue ResidentMacrophages Limits Transduction of Target CellsChelsea M. Bolyard, Jeffrey S. Bartlett.548Overcoming Anti-AAV Neutralizing Antibodies with AlternateSerotype and Pharmacological StrategiesFederico Mingozzi, Margriet J. Vervoordeldonk, Yifeng Chen, Shyrie Edmonson, RogierThurlings, Katherine High, Paul P. Tak.549Switching the Fiber Knob of Oncolytic Adenoviruses To AvoidNeutralizing Antibodies in Human Cancer PatientsMari Raki, Iulia Diaconu, Merja Sarkioja, Sophie Escutenaire, Lotta Kangasniemi, AnnaKanerva, Vincenzo Cerullo, Timo Joensuu, Sari Pesonen, Akseli Hemminki.550Depletion of B Cells by Anti-CD20 Partially Regulates Anti-FVIIIAntibody Production in the Nonviral Gene Therapy ModelPeiqing Ye, Baowei Peng, Marilyn Kehry, David J. Rawlings, Carol H. Miao.551Sheep Harbor Naturally-Occurring Antibodies to Human AAV: A NewLarge Animal Model for AAV ImmunologyJoseph Tellez, Jonathan D. Finn, Nick Tschernia, Graça Almeida-Porada, Valder R. Arruda,Christopher D. Porada.552Effects of Various TLR/Inflammation Pathways on Humoral andCellular Immune Response to rAAV1 in MiceMuriel Sudres, Virginie Vasseur, Séverine Ciré, Bernhard Ryffel, Anne Galy.553Monitoring and Suppression of Immune Responses to AAV-MediatedGene Therapy in Canine MuscleZejing Wang, Rainer Storb, Donghoon Lee, Martin Kushmeric, Baocheng Chu, JefferyChamberlain, Stainly Riddell, Stephen Tapscott.554Prevalence of Neutralizing Antibodies Against Adeno-AssociatedVirus 2, 8 and 9 in Non-Human Primate ColoniesHiroya Yagi, Hiroaki Mizukami, Tomonori Tsukahara, Masashi Urabe, Hiromi Hamada,Akihiro Kume, Hiroyuki Yoshikawa, Keiya Ozawa.Oligonucleotide & RNAi Therapeutics II555Dual Function BAFF Receptor Aptamers Block BAFF1 Ligand InducedProliferation and Deliver siRNAS to NHL CellsKatrin Tiemann, Stephen J. Forman, John J. Rossi, Jiehua Zhou.556Efficient Delivery of siRNAs into Primary Cells In Vitro andSystemically In Vivo Using Chemically Modified PepFect PeptidesSamir El Andaloussi, Edvard C. I. Smith, Ülo Langel.Friday, May 21 st

120American Society of Gene & Cell TherapyAbstract DirectoryFriday, May 21 stFriday, May 21, 2010Poster Session II — continued6:30 PM - 8:30 PMRoom: Exhibit Hall C & B-SouthOligonucleotide & RNAi Therapeutics II557Reduction of Mutant Huntingtin by Antisense OligonucleotidesAmeliorates Phenotypic Deficits in YAC128 Mouse Model ofHuntington’s DiseaseJonathan A. Fidler, Lisa M. Stanek, Wendy Yang, Amy M. Richards, Edward Wancewicz,Curt Mazur, Gene Hung, C. Frank Bennett, Seng H. Cheng, Lamya S. Shihabuddin.558Antibody-Mediated Targeting of pH-Responsive NanoparticlesFacilitates siRNA Delivery to Cancer CellsMaria C. Palanca-Wessels, Richelle Cutler-Strom, Anthony C. Convertine, Fan Lee,Michael F. Press, Scott E. James, Patrick S. Stayton, Oliver W. Press.559Adenoviral shRNA-Mediated Knockdown of TNFR1(P55) EitherLocally in the Knee Joint or Systemically Ameliorates Collagen-Induced ArthritisOnno J. Arntz, Jeroen Geurts, Sharon Veenbergen, Miranda B. Bennink, Wim B. van denBerg, Fons A. J. van de Loo.560Specific and Efficacious RNA Aptamer Against Hepatic Metastasis ofColon CancerSeong-Wook Lee, Young Ju Lee, Seung Ryul Han, Min jung Kim, Hanna Cho, Won IlLee, Jin-Sook Jeong.561Development of Aptamer Therapeutics Against Cell Surface Receptorsfor Lymphoma and Auto-Immune DiseasesElizabeth D. Pratico, David Boczkowski, Smita Nair, Bruce A. Sullenger.562A Microscopic Study of the Intracellular Fate of Cationic MediatedsiRNA DeliveryMeysam Abbasi, Rakesh Bhatnagar, Hasan Uludag.563Deriving Effective Anti-HIV Guide Sequences from Enhanced PrimarymicroRNA Secondary StructuresFiona van den Berg, Patrick Arbuthnot, Marc S. Weinberg.564“Bifunctional” shRNA Strategy for Cancer Gene and Cell TherapyDonald D. Rao, Zhaohui Wang, Padmasini Kumar, Yang Yu, Shihe Liu, Chris M. Jay,Nancy S. Templeton, Courtney Haddock, John Vorhies, Alex W. Tong, Phillip B. Maples,Neil Senzer, F. C. Brunicardi, John Nemunaitis.565Feasibility and Effectiveness of Exon 51 skipping in Human-Like mdxMutationYoshitsugu Aoki, Toshifumi Yokota, Takashi Saito, Akinori Nakamura, Tetsuya Nagata,Hitoshi Okazawa, Shin’ichi Takeda.566The Effect of RNA Interfering a1,3GT and NF-kB in CardiacXenotransplantationFeng Qi, Chengyu Lv, Yachuan Gu, Xianghui He, Liwei Zhu.567Inhibition of Breast Cancer Cell Growth Via Silencing IKKeBin Qin, Ravi S. Shukla, Kun Cheng.568Cationic Polymer Mediated siRNA Delivery for P-glycoprotein (P-gp)Down-Regulation in Tumor CellsMeysam Abbasi, Afsaneh Lavasanifar, Michael Weinfeld, Hasan Uludag.569Gene Editing Induces Double-Stranded Breakage in Mammalian CellsMelissa A. Bonner, Eric B. Kmiec.Cell Processing and Vector Production II570Development of a MDCK Cell Line for the Manufacturing of CanineAdenovirus Type 2 (CAV-2) VectorsVirgínia Santiago, Eric Kremer, Paula M. Alves, Ana S. Coroadinha.571Production of a rAAV1-CB-hAAT Human Clinical Trial Lot by rHSVCo-Infection of Suspension BHK CellsDavid R. Knop, Brad Grimm, Lijun Wang, Darby L. Thomas, Guo-jie Ye.572RNA Based Plasmid Selection System for Antibiotic-Free PlasmidDNA Vector ProductionAaron E. Carnes, Jeremy M. Luke, Justin M. Vincent, Clague P. Hodgson, James A.Williams.573Robust Recombinase-Free System Production of Helper-DependentAdenoviral Vectors with Negligible Contamination by DelayedPackaging ProcessDan Cots, Raul Alba, Patrick Hearing, Eric J. Kremer, Maria Mercedes Segura, AssumpcióBosch, Miguel Chillón.574Removal of Clinically Relevant Contaminants from cGMP GradePreparations of Plasmid DNA: Implications for Non-Viral GeneTherapy and DNA-Based VaccinesNancy S. Templeton, Pervez Firozi, Wei Zhang, Li Chen, Florante A. Quiocho, Kim C.Worley, Phillip B. Maples, John Nemunaitis.EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010121Abstract DirectoryFriday, May 21, 2010Poster Session II — continued6:30 PM - 8:30 PMRoom: Exhibit Hall C & B-SouthCell Processing and Vector Production II575Escherichia coli Plasmid DNA Fermentation Strain and Process-SpecificEffects on Vector Yield, Quality and Transgene ExpressionAaron E. Carnes, Jeremy M. Luke, Justin M. Vincent, Clague P. Hodgson, James A.Williams.576An Assay To Monitor the Residual Contamination in the PlasmidDNA Manufacturing Area Based on the Correlation of Plasmid DNAConcentration to TOCRameswari Rameswaran, Lee Allen, Shane Johnson, Henry Hebel.577Counting and Sizing of Viral Vector Particles and Aggregates byNanoparticle Tracking Analysis (NTA)Andrew Malloy, Duncan Griffiths, Patrick Hole, Bob Carr.578Manufacturing and Stability Testing of a GNE-Lipoplex for a ClinicalTrial for the Treatment of Hereditary Inclusion Body Myopathy Type(HIBM)Chris M. Jay, Courtney Haddock, Phillip B. Maples, John Nemunaitis.579Dissolved Oxygen and pH Profile Evolution in Shake Flasks during293 Cell Growth and Infection with AdenovirusAna Carina Silva, Daniel Simão, Marcos F. Q. Sousa, Pedro E. Cruz, Manuel J. T.Carrondo, Paula M. Alves.Late Breaking Science II933Targeted Lentiviral Vectors for the Gene Therapy of X-Linked ChronicGranulomatous DiseaseChristian Brendel, Stefan Schultze-Strasser, Uta Müller-Kuller,Serap Tokmak, HanaKunkel, Linping Chen-Wichmann, Stefan Stein, Eva Rudolf, Michael Antoniou, ManuelGrez934Meganucleases: A Novel Anti-Viral ApproachJulianne Smith, Roman Galetto, Stephanie Grosse, Cécile Schiffer Mannioui, SylvainArnould, Marine Gailledrat, Philippe Duchateau, Frédéric Pâques & Carole Desseaux935Monomeric Designer T Cells are More Potent against IL13Ra2Expressing GBMSeogkyoung Kong, Richard P Junghans, , Prakash Sampath936pSuperShuttle – An Easy Method for Modifications at any Site in theAdenoviral Genome by Conventional Bacterial RecombinationDaniel Oberg, Nick R Lemoine, Gunnel Hallden937Generation and Characterization of Lipid-Encapsulated AAV vectors:A Strategy to Evade Neutralization by AAV AntibodiesJ. Fraser Wright, Sissel Lund-KatzFriday, May 21 st

122American Society of Gene & Cell TherapyAbstract DirectorySaturday, May 22 ndSaturday, May 22, 2010Oral Abstract Session 410Musculo-skeletal Gene & Cell Therapy11:00 AM - 1:00 PMRoom: Delaware Suite580 11:00 AMIrradiation of Adult mdx Mice Prior to Full-Length Murine DystrophincDNA Transfer Results in a Delayed and Diminished Anti-DystrophinHost Immune ResponseSaman Eghtesad, Heng Zheng, Hiroyuki Nakai, Michael W. Epperly, Paula R. Clemens.581 11:15 AMTransient Expression of a Therapeutic Dystrophin Transgene inDuchenne Muscular Dystrophy Revealed by T Cell Mediated ImmunityJerry R. Mendell, Katherine Campbell, Louise R. Rodino-Klapac, Zarife Sahenk, ChristopherShilling, Sarah Lewis, Dawn Bowles, Steven Gray, Chengwin Li, Gloria Galloway, VinodMalik, Brian Coley, K. Reed Clark, Juan Li, Xiao Xiao, Jade Samulski, Scott McPhee, R.Jude Samulski, Christopher M. Walker.582 11:30 AMInduction of Oral Immunotolerance to rAAV9-Microdystrophin inCanine X-Linked Muscular DystrophyHiromi H. Kinoh, Naoko Yugeta, Hironori Okada, Yuko N. Kasahara, Takashi Okada,Shin’ichi Takeda.583 11:45 AMBaculovirus-Engineered Mesenchymal Stem Cells Heal the Critical-Sized Femoral Segmental Bone Defects in RabbitsChin-Yu Lin, Yu-Han Chang, Kun-Ju Lin, Tzu-Chen Yen, Wen-Yi Lo, Chia-Hsin Luo, Ching-Lung Tai, Yu-Chen Hu.584 12:00 PMGenetic Evidence for a Structural Role of a–dystrobrevin-3 within theDystrophin-Glycoprotein ComplexGuy L. Odom, Glen B. Banks, Dewayne Townsend, Marvin E. Adams, Joseph M. Metzger,Stanely C. Froehner, Jeffrey S. Chamberlain.585 12:15 PMrAAV8-Mediated Protein-Anchoring Therapy for Targeting CollagenQ-Tailed Acetylcholinesterase to the Neuromuscular JunctionMikako Ito, Yumi Suzuki, Takashi Okada, Takayasu Fukudome, Toshiro Yoshimura, AkioMasuda, Shin’ichi Takeda, Eric Krejci, Kinji Ohno.586 12:30 PMA Single Patient, Multiple Intravenous (IV) Infusion, Clinical Trial ofGNE-Lipoplex for Therapy of Hereditary Inclusion Body Myopathy(HIBM)Gregory Nemunaitis, Chris M. Jay, Neil Senzer, Henry Allen, Anagha P. Phadke, Nancy S.Templeton, Phillip B. Maples, John Nemunaitis.587 12:45 PMSuccessful Expression of a R16/17 Micro-Dystrophin Gene inDystrophic Dogs with a Tyrosine-Mutant AAV Vector and a BriefCourse of Immune SuppressionJin-Hong Shin, Yi Lai, Yongping Yue, Arun Srivastava, Bruce F. Smith, Dongsheng Duan.Oral Abstract Session 411Chemical and Molecular Conjugates11:00 AM - 1:00 PMRoom: Virginia Suite588 11:00 AMTranscription Factor Binding by Plasmid DNA Is Needed forInteraction with Microtubules and Trafficking in CellsMelissa A. Badding, Erin E. Vaughan, David A. Dean.589 11:15 AMQuantitative Analysis of the Effect of Functional Peptides onIntracellular Trafficking of Polymer Gene Delivery SystemsNicole M. Moore, Denis Pristinski, Shelly E. Sakiyama-Elbert.590 11:30 AMThe Effects of PNA-Based prePEGylation on the In Vitro and In VivoProperties of DNA PolyplexesPeter G. Millili, Ulhas P. Naik, Millicent O. Sullivan.591 11:45 AMParticle Tracking for Intracellular Trafficking of Octaarginine-ModifiedLiposome: Comparative Study with AdenovirusHidetaka Akita, Kaoru Enoto, Tomoya Masuda, Hiroyuki Mizuguchi, Tomomi Tani,Hideyoshi Harashima.592 12:00 PMAdvanced In Vitro Models Combined with MathematicalRepresentations Yield New Quantitative Understanding of SyntheticGene Delivery System PerformanceMichelle C. Lowe, Todd D. Giorgio.593 12:15 PMGene Therapy of the Blood Brain Barrier: Systemic Delivery ofshRNA-Producing Plasmid DNA for Transient Suppression of MRP4Drug Efflux Transporter ProteinHongwei Zhang, Michelle L. Varney, Rakesh K. Singh, Serguei V. Vinogradov.594 12:30 PMPEGylated Polyacridine-Peptide DNA Open-Polyplexes with LongPharmacokinetic Half-Life Have Improved Hydrodynamic StimulatedGene ExpressionChristian A. Fernandez, Nicholas J. Baumhover, Jason Duskey, Sanjib Khargharia, KevinG. Rice.595 12:45 PMSuccessful Gene Delivery with Receptor-Targeted PAMAMDendrimers Occurs Via Caveolae-Mediated PathwaysMark E. Hwang, William R. Gunther, Daniel W. Pack.EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010123Abstract DirectorySaturday, May 22, 2010Oral Abstract Session 412Cardiovascular Gene & Cell Therapy11:00 AM - 1:00 PMRoom: Wilson ABC596 11:00 AMSystemic Delivery of AAV2/9 Vectors Improve Cardiac Function inPompe DiseaseDarin J. Falk, Meghan S. Soustek, Cathryn S. Mah, Denise A. Cloutier, Sean A. Germain,Barry J. Byrne.597 11:15 AMCoordinated Co-Expression of VEGF 164and PDGF-BB PreventsAberrant Angiogenesis and Accelerates Vascular StabilizationRoberto Gianni-Barrera, Silvia Reginato, Thomas Wolff, Lorenz Gürke, Michael Heberer,Andrea Banfi.598 11:30 AMMitral Valve Disease Is Due to Abnormal Collagen Structure in CanineMucopolysaccharidosis I and VII and Can Be Reduced with NeonatalIntravenous Injection of a Gamma Retroviral VectorKatherine P. Ponder, Meg M. Sleeper, Susan Wu, Patricia O’Donnell, Mark E. Haskins.599 11:45 AMAAV9-Mediated proBNP Delivery Improves Diastolic Performance ina Model of Spontaneous Hypertensive RatsJason M. Tonne, Jarryd M. Campbell, Diego Bellavia, Elise A. Oehler, Fernando L. Martin,Alessandro Cataliotti, John C. Burnett, Yasuhiro Ikeda.600 12:00 PMIn Vivo Over-Expression of a b-Adrenergic Receptor Kinase InhibitorUsing scAAV6-Mediated Molecular Cardiac Surgery with RecirculatingDelivery (MCARD) Enhances Cardiac FunctionJaBaris D. Swain, Michael G. Katz, Anthony Fargnoli, Marina Sumaroka, CatherineTomasulo, Mihail Petrov, James J. Pilla, Hansell H. Stedman, Walter J. Koch, JosephRabinowitz, Charles R. Bridges.601 12:15 PMAAV-Mediated SERCA2a Expression Improves theElectrocardiographic Profile of Aged mdx MiceJin-Hong Shin, Brian P. Bostick, Yongping Yue, Roger J. Hajjar, Dongsheng Duan.602 12:30 PMRNAi-Mediated Knockdown of HMG CoA Reductase In Vitro and InVivo Increases Transgene Expression from Genomic LDLR Mini-GeneVectorsOlivia C. Hibbitt, Sarina Agkatsev, Carina Owen, Len Seymour, Keith M. Channon,Richard Wade-Martins.603 12:45 PMSDF-1a-Engineered Cell-Based Therapy for Diabetic Wound HealingZhao-Jun Liu, Runxia Tian, Weijun An, Ying Zhuge, Yan Li, Hongwei Shao, Bianca Habib,Omaida C. Velazquez.Oral Abstract Session 413Cancer-Oncolytic Viruses II11:00 AM - 1:00 PMRoom: Marriott Ballroom Salons 2 & 3604 11:00 AMHigh Resolution Analysis of the Intratumoral Spread of anIntravenously Administered Oncolytic VirusShruthi Naik, Rebecca Nace, Elizabeth Hadac, Glen Barber, Stephen J. Russell.605 Abstract Withdrawn191 11:15 AMA Comparative Study of Stem Cell-Based Cell Carrier Systems for theSystemic Delivery of an Oncolytic Adenovirus for Antiglioma TherapyMatthew A. Tayler, Atique U. Ahmed, Ilya V. Ulasov, Irina Y. Balyasnikova, Maciej S.Lesniak.606 11:30 AMCombination of Anti Angiogenic Cancer Therapy with SystemicOncolytic Virotherapy To Treat Established TumorsTimothy Kottke, Geoff Hall, Jose Pulido, Rosa Diaz, Jill Thompson, DebabrataMukhopadhyay, Heung Chong, Peter Selby, Matt Coffey, Hardev Pandha, John Chester,Alan Melcher, Kevin Harrington, Richard Vile.607 11:45 AMThe Type III Interferon IL-28 Mediates Anti Tumor Efficacy ofOncolytic VSV in a Fully Immune Competent ModelPhonphimon Wongthida, Rosa Diaz, Feorillo Galivo, Timothy Kottke, Jill Thompson, JosePulido, Kevin Pavelko, Larry Pease, Alan Melcher, Richard Vile.608 12:00 PMA New Oncolytic Herpes Simplex Virus That Synergizes with SmallMolecule Inhibitors of PI3K/Akt To Treat Malignant GliomaRyuichi Kanai, Matthew Gardner, Hiroaki Wakimoto, Robert L. Martuza, Samuel D.Rabkin.609 12:15 PMImproving the Lytic Capacity of a Conditionally ReplicativeAdenoviruses by Incorporating Promoter Elements Responsive toTumor Environmental ConditonsDiego L. Viale, Veronica M. Lopez, Eduardo G. Cafferata, David Gould, Yuti Chenajovsky,Osvaldo L. Podhajcer.610 12:30 PMDefining the Role of Innate Immune Mechanisms in the Efficacy ofOncolytic VSV Virotherapy in a Fully Immune Competent ModelPhonphimon Wongthida, Rosa Diaz, Feorillo Galivo, Timothy Kottke, Jill Thompson, JosePulido, Alan Melcher, Richard Vile.611 12:45 PMDifferential Effects of VSV and Cyclophosphamide on NK CellsLeads to Antagonistic Effects on Anti-Tumor Therapy of a MurineMesothelioma ModelCandice L. Willmon, Jill Thompson, Timothy Kottke, Stephen Albelda, Richard Vile.Saturday, May 22 nd

124American Society of Gene & Cell TherapyAbstract DirectorySaturday, May 22 ndSaturday, May 22, 2010Oral Abstract Session 414Hematologic/Immunologic: Clinical, Preclinical and Safety11:00 AM - 1:00 PMRoom: Maryland Suite612 11:00 AMPolyclonal Reconstitution of the Hematopoietic System in TwoPatients of a WAS Clinical Gene Therapy TrialAnna Paruzynski, Kaan Boztug, Claudia Ball, Ali Nowrouzi, Christina Lulay, Marie Böhm,Sonja Naundorf, Klaus Kühlke, Rainer Blasczyk, Irina Kondratenko, Laszló Maródi,Hanno Glimm, Christoph Klein, Christof von Kalle, Manfred Schmidt.613 11:15 AMSustained Partial Phenotypic Correction of Hemophilia B in the Dogby a microRNA-Regulated Lentiviral VectorAlessio Cantore, Marco Ranzani, Lucia Sergi Sergi, Giuliana Vallanti, Marina Radrizzani,Brian Brown, Eugenio Montini, Timothy Nichols, Luigi Naldini.614 11:30 AMTiming of Anti-T Cell Immunosuppressive Therapy Is Critical for theSafety of Liver Mediated AAV2 Transduction in Rhesus MacaquesJonathan D. Finn, Patricia Favaro, J. Fraser Wright, Federico Mingozzi, Katherine A.High, Valder R. Arruda.615 11:45 AMFactor IX-R338L (FIX Padua) as a Novel Alternative for theTreatment of Canine Severe Hemophilia BJonathan D. Finn, Paolo Simioni, Nicholas Iacobelli, Shangzhen Zhou, Timothy C.Nichols, Katherine A. High, Valder R. Arruda.616 12:00 PMErythropoeisis Sustained 1 Year by the EPODURE BioPump inPatients with Chronic Kidney Disease: Further Results of Phase I/IIProof of Concept TrialBaruch S. Stern, Ehud Shoshani, Andrew L. Pearlman, Philip Ng, Allen R. Nissenson,Eithan Galun, Anatole Besarab, Avi Rimler, Haim Goltzmann, Reem Miari, Alex Okun,Haddas Bookay, Tamar Jibly, Javier A. Abrameto, Michal Elhalel.617 12:15 PMLentiviral Gene Therapy of RAG1 Severe CombinedImmunodeficiency: Risks and Implications for TreatmentNiek P. van Til, Roya Sarwari, Trudi P. Visser, Helen de Boer, Yuedan Li, Julia Hauer,Chantal Lagresle-Peyrou, Olivier Danos, Arnaud Jollet, Fang Zhang, Adrian Thrasher,Barbara Cassani, Monique M. Verstegen, Anna Villa, Marina Cavazzana-Calvo, GerardWagemaker.618 12:30 PMDisruption of Glucocorticoid Regulation in Therapeutic Human T Cellswith Zinc Finger NucleasesRebecca A. Gardner, Andreas Reik, Carolina Berger, Seitaro Terakura, Philip D. Gregory,Michael C. Jensen, Michael C. Holmes, Stanley R. Riddell.619 12:45 PMLentiviral Gene Transfer under Optimized Cytokine ConditionsFacilitates Polyclonal Hematopoiesis of Recipient MiceTobias Maetzig, Martijn H. Brugman, Olga S. Kustikova, Zhixiong Li, Melanie Galla, NielsHeinz, Ute Modlich, Bernhard Schiedlmeier, Axel Schambach, Christopher Baum.Oral Abstract Session 415Lung and Respiratory Disease Gene & Cell Therapy11:00 AM - 12:00 PMRoom: Thurgood Marshall W620 11:00 AMGeneration of a Transgenic Gut-Corrected CFTR Knockout FerretModel with Intestinal-Specific Expression of Ferret CFTRXiaoming Liu, Xingshen Sun, John T. Fisher, Meihui Luo, Hongshu Shui, Ziying Yan,Yaling Yi, Michael J. Goodheart, Gergely Lukacs, David Meyerholz, John F. Engelhardt.621 11:15 AMPersistent Long Term Lentiviral Correction of the CFTR Gene Defect inCystic Fibrosis MicePatricia Cmielewski, Donald Anson, David W. Parsons.622 11:30 AMDevelopment of Optimized hCFTR Gene Sequence and ProlongedExpression Vector for Cystic Fibrosis TherapyLinas Padegimas, Karla A. Dines, Samuel J. Adams, Sharon M. Oette, Susannah L. Hyatt,Olena Tyr, Christopher R. Gedeon, Ozge Sesenoglu-Laird, Robert C. Moen, Tomasz H.Kowalczyk, Mark J. Cooper.623 11:45 AMExpression of Human Alpha-1 Antitrypsin in Mice and Dogs FollowingAAV6 Vector-Mediated Gene Transfer to the LungsChristine L. Halbert, David K. Madtes, Andrew E. Vaughan, Zejing Wang, Rainer Storb,Stephen J. Tapscott, A. Dusty Miller.Oral Abstract Session 416Gene Regulation12:15 PM - 1:15 PMRoom: Thurgood Marshall W624 12:15 PMEngineered Zinc Finger Transcription Factors for the Treatment ofGain of Function MutationsClaudio Mussolino, Daniela Sanges, Ciro Bonetti, Elena Marrocco, Umberto Di Vicino,Valeria Marigo, Alberto Auricchio, Germana Meroni, Enrico M. Surace.625 12:30 PMAAV Vectors for Tissue-Specific, Regulated Expression in Heart, Liverand LungShu-Jen Chen, Maria P. Limberis, Lawrence Bish, Ruben Hovhannisyan, Sheena Saighal,Odella Jno-Charles, H. Lee Sweeney, Arbans Sandhu, Julie Johnston, James M. Wilson.EXHIBITOR PROSPECTUSfinal program

126American Society of Gene & Cell TherapyAbstract DirectorySaturday, May 22 ndSaturday, May 22, 2010Oral Abstract Session 430 — continuedAdenovirus and Other DNA Virus Vectors3:00 PM - 5:00 PMRoom: Maryland Suite642 4:30 PMThe Cytoplasmic Sensor, NOD2, Induces the Innate Immune Responseand Transgene Silencing of Vector after Systemic Administration ofHelper-Dependent AdenovirusMasataka Suzuki, Vincenzo Cerullo, Racel G. Cela, Terry K. Bertin, Christian Clarke, LeeH. Brendan.643 4:45 PMCAdVax-Vectored Multivalent Filovirus Vaccine Protects NHP AgainstChallenge at 1000 Times the Lethal Dose of Ebola and MarburgVirusesJohn Y. Dong, Danher Wang, William D. Pratt.Oral Abstract Session 431Infectious Diseases and Vaccines3:00 PM - 5:00 PMRoom: Delaware Suite644 3:00 PMChim3 as a New Transgene for Anti-HIV-1/AIDS Gene Therapy:Antiviral Effect and Survival Advantage Features in a Preclinical InVitro ModelSimona Porcellini, Luca Alberici, Francesco Gubinelli, Gian-Paolo Rizzardi, ChiaraBovolenta.645 3:15 PMIn Vivo Selection of CD4 + T Cells Transduced with a Gamma-Retroviral Vector Expressing a Single-Chain Intrabody DirectedAgainst HIV-1 TatStephen E. Braun, Ran Taube, Quan Zhu, Fay E. Wong, Akikazu Murakami, Erick Kamau,Markryan Dwyer, Angela Carville, R. Paul Johnson, Wayne A. Marasco.646 3:30 PMSafety and Efficacy of Autologous CD4+ T cells Transduced with aLentiviral Vector Delivering Anti-HIV RNA Antisense env in HIV+Subjects Failing One or More HAART RegimensTessio Rebello, David Stein, Gary Blick, Richard Greenberg, Clifford Kinder, AndrewZolopa, Gerard McGarrity.647 3:45 PMLentiviral Delivery of TRIM-Cyclophilin Restriction Factors AgainstHIV-1Emma Chan, Torsten Schaller, Lu Zhao, Adrian Thrasher, Greg Towers, Waseem Qasim.648 4:00 PMDNA Vaccination with a Consensus H1HA Influenza ImmunogenInduces Immune Responses Capable of Protecting from a Lethal NovelA/H1N1-2009 and A/H1N1-1918 ChallengeM. P. Morrow, J. Yan, A. Khan, M. Pope, A. Patel, G. Kobinger, D. B. Weiner, N. Y.Sardesai.649 4:15 PMInduction of Immune Responses Against Multiple Species ofEbolavirus Using DNA and Retroviral-Based Virus-Like ParticlesBearing the Envelope Glycoprotein of a Single Species ZaireEbolavirusWu Ou, Josie Delisle, Carolyn Wilson.650 4:30 PMLow Levels of CXCR4 Are Sufficient for HIV-1 Entry and InfectionJinyun Yuan, Charles DeRossi, Michael C. Holmes, Philip D. Gregory, Bruce E. Torbett.651 4:45 PMOverexpression of the SLAM Receptor Adaptor Molecule EAT-2 as aNovel Strategy for Enhancing Cellular Immunity to HIVantigensYasser A. Aldhamen, Daniel M. Appledorn, Sergey S. Seregin, Joyce C. Liu, Nathan J.Schuldt, Sarah S. Godbehere, Andrea Amalfitano.Oral Abstract Session 432Cancer – Immunotherapy II3:00 PM - 5:00 PMRoom: Marriott Ballroom Salons 2 & 3652 3:00 PMA Powerful Retroviral Vector for TCR Gene Therapy: Silencing ofEndogenous TCR Improved Expression and Anti-Tumor Reactivity ofTransduced Tumor-Specific TCRs in Human LymphocytesSachiko Okamoto, Hiroaki Ikeda, Hiroshi Fujiwara, Masaki Yasukawa, Hiroshi Shiku,Junichi Mineno.653 3:15 PMOrgan Specific Oncolytic Virus Incorporated Antigen Libraries(OSOVIAL) for the Immunotherapy of CancerJose Pulido, Timothy Kottke, Jill Thompson, Peter Selby, Alan Melcher, Richard Vile.654 3:30 PMEditing Human Lymphocyte Specificity for Safe and Effective AdoptiveImmunotherapy of LeukemiaElena Provasi, Pietro Genovese, Zulma Magnani, Angelo Lombardo, Andreas Reik, LiuPei-Qi, Oscar Muniz Pello, Jurgen Kuball, Attilio Bondanza, Giulia Casorati, Philip D.Gregory, Claudio Bordignon, Michael C. Holmes, Philip D. Greenberg, Luigi Naldini,Chiara Bonini.655 3:45 PMConstitutive 4-1BBL Expression Dramatically Increases Proliferation,Survival and In Vivo Persistence of CD19-Targeted T Cells, PromotingComplete Tumor EliminationMaud Condomines, Jason Plotkin, John C. Markley, Gertrude Gunset, Michel Sadelain.EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010127Abstract DirectorySaturday, May 22, 2010Oral Abstract Session 432 — continuedCancer – Immunotherapy II3:00 PM - 5:00 PMRoom: Marriott Ballroom Salons 2 & 3656 4:00 PMAn A20-Silenced, Stroma-Targeted DC Vaccine Reverses theImmunosuppressive Tumor Microenviroment Resulting in PotentAntitumor ActivityXiao-Tong Song, Xiaoou Zhou, Lisa Rollins, Cliona M. Rooney, Stephen Gottschalk.657 4:15 PMA CD46-Targeting Recombinant Protein that Increases theTherapeutic Efficacy of Monoclonal Antibodies for CancerHongjie Wang, Ying Liu, Zong Li, Akseli Hemminki, Andre Lieber.658 4:30 PMTreatment of Cancer Patients with Integrin-Targeted OncolyticAdenoviruses Ad5-D24-RGD and Ad5-RGD-D24-GMCSFSari Pesonen, Vincenzo Cerullo, Sophie Escutenaire, Mari Raki, Lotta Kangasniemi, EerikaKarli, Elina Haavisto, Minna Oksanen, Timo Joensuu, Anna Kanerva, Akseli Hemminki.659 4:45 PMEffective Dendritic Cell Immuno-Gene Therapy of Established ErbB2-Expressing Tumors Using Pentostatin-Based Host Immune Depletionand Subsequent Host Th1/Tc1 Cell TransferMiriam Mossoba, Jason Foley, Anu Gangopadhyay, Kris Ylaya, Matthew Winterton,Justin Taylor, Paul Massey, Stephen M. Hewitt, Jeffrey A. Medin, Daniel H. Fowler.Oral Abstract Session 433Oligonucleotide & RNAi Therapeutics II3:00 PM - 5:00 PMRoom: Thurgood Marshall W660 3:00 PMAlleviation of Potentially Adverse shRNA Off-Targeting Via AAVVector-Encoded Passenger Strand DecoysStefan Mockenhaupt, Nina Schürmann, Dirk Grimm.661 3:15 PMMultiplexing of snoRNAs for HIV-1 InhibitionJane Zhang, John J. Rossi.662 3:30 PMDelivery of Chemo-Sensitizing siRNAs to HER2-Positive BreastCancer Cells Using RNA AptamersKristina W. Thiel, William H. Thiel, Xiuying Liu, Justin P. Dassie, Katie R. Stockdale,William M. Rockey, James O. McNamara, II, Paloma H. Giangrande.663 3:45 PMMethods for Isolating Cell-Internalizing RNA Aptamers for TargetedsiRNA DeliveryWilliam H. Thiel, Kristina W. Thiel, Justin P. Dassie, Liu Xiuying, Katie R. Stockdale,William M. Rockey, James O. McNamara, II, Paloma H. Giangrande.664 4:00 PMTreatment with the TLR9 Agonist MGN1703 in Patients withMetastatic Solid Tumors – EFFICACY Results of a Phase 1 ClinicalStudyMartin R. Weihrauch, Manuel Schmidt, Heike Richly, Bahar Bahar, Michael S. vonBergwelt-Baildon, Ulrich Hacker, Alexander Shimabukuro-Vornhagen, Marina Tschaika,Burghardt Wittig, Max E. Scheulen.665 4:15 PMmiR-7 Inhibits Schwannoma Tumor Growth by Directly Targetingp21-Activated Kinase 1 and Epidermal Growth Factor ReceptorOkay Saydam, Ozlem Senol, Arda Mizrak, Thomas Wurdinger, Anat O. Stemmer-Rachamimov, Anna M. Krichevsky, Xandra O. Breakefield.666 4:30 PMNanoparticles are Effective Vehicles for Systemic Delivery of2’OMePS Antisense Oligonucleotides in Exon Skipping-MediatedDystrophin RestorationAlessandra Ferlini, Marina Fabris, Elena Bassi, Sofia Falzarano, Daniela Perrone,Francesca Gualandi, Patrizia Sabatelli, Luciano Merlini, Paola Rimessi.667 4:45 PMTherapy for Vaso-Occlusion in Sickle Cell Disease Includes RNAAptamerAngela D. Burnette, Jun-ichi Nishimura, Milena Batchvarova, Shahid M. Nimjee, RahimaZenadi, Marilyn J. Telen, Bruce A. Sullenger.Oral Abstract Session 434Cell Processing and Vector Production3:00 PM - 5:00 PMRoom: Marriott Ballroom Salon 1668 3:00 PMGMP Production of Self-Complementary Serotype 8 AAV Vector forTreatment of Hemophilia BJames A. Allay, John S. Coleman, Arthur W. Nienhuis, Andrew Davidoff, Amit C.Nathwani, Susan Sleep, John T. Gray.669 3:15 PMProduction of Lentiviral Vectors in Suspension Cells UsingRecombinant BaculovirusesHanna P. Lesch, Anna E. Laitinen, Lauri M. Laitinen, Jere T. Pikkarainen, HarithaSamaranayake, Seppo Ylä-Herttuala, Kari J. Airenne.670 3:30 PMIncreased Therapeutic Effect of Cell Transplantation for WoundHealing in Diabetic Mice by Prolonging the Survival of TransplantedCells Using Adhesamine, a Synthetic Adhesion MoleculeTetsuya Suehara, Makiya Nishikawa, Yuki Takahashi, Sayumi Yamazoe, MotonariUesugi, Yoshinobu Takakura.671 3:45 PMCharacterization of Positioning Effect of pol III-shRNA TranscriptionUnit in scAAV Vector Genome on the Packaging Efficiency andFunctionality of shRNA SilencingJun Xie, Ran He, Qin Su, Guangping Gao.J. Telen, Bruce A. Sullenger.Saturday, May 22 nd

128American Society of Gene & Cell TherapyAbstract DirectorySaturday, May 22, 2010Oral Abstract Session 434 — continuedCell Processing and Vector Production3:00 PM - 5:00 PMRoom: Marriott Ballroom Salon 1672 4:00 PMRapid Production of High Titer Virus Using a Concentrated RetrovirusExpansion DeviceCeidy Sanchez, Gianpietro Dotti, John Wilson, Cliona M. Rooney, Malcolm K. Brenner,Juan F. Vera.673 4:15 PMA Novel Approach to Developing Recombinant AAV Producing CellLinesJingmin Zhou, Katherine A. High, Guang Qu.674 4:30 PMAn Efficient and Complete Platform for the Production and Use ofLentiviral VectorsThomas Quinn, Chris Mello, Lily Lee, Mei Fong, Dwayne Bisgrove, Michael Haugwitz,Hiroaki Sagawa.675 4:45 PMDevelopment, Scale-Up and Technology Transfer for Rapid,Automated, cGMP Compliant, Large-Volume Suspension Cell BasedProcess for Lentiviral Vector ProductionJames Brady, Linhong Li, Scott R. Witting, Cornell Allen, Rama Shivakumar, Aparna Jasti,Kenneth G. Cornetta, Madhusudan V. Peshwa.678 3:30 PMUpdate of Stem Cell Gene Therapy Clinical Trial for ADA-Deficiency inJapanMakoto Otsu, Masafumi Yamada, Yoshihiro Maeyama, Miyuki Kida, Satoru Nakajima,Nariaki Toita, Norikazu Hatano, Ryouji Kobayashi, Osamu Tatsuzawa, Junichi Mineno,Masafumi Onodera, Pawan Bali, Michael S. Hershfield, Fabio Candotti, NobuakiKawamura, Yukio Sakiyama, Tadashi Ariga.679 3:45 PMRescue and Long-Term Outcome of a Murine Model of MethylmalonicAcidemia Following Liver-Directed, AAV-Mediated Gene TherapyRandy J. Chandler, Nuria Carillo-Carrasco, Suma Chandrasekaran, Charles P. Venditti.680 4:00 PMAAV Vector Mediated Enzyme Replacement Therapy ofHypophosphatasia (HPP) Model MiceTae Matsumoto, Seiko Yamamoto, Hideo Orimo, Koichi Miyake, Noriko Miyake, SonokoNarisawa, José Luis Millán, Yoshitaka Fukunaga, Takashi Shimada.681 4:15 PMrDNA-AAV Vectors for the Treatment of PhenylketonuriaNick Morcinek, Laura M. Roy, Zhongya Wang, Markus Grompe, Cary Harding.682 4:30 PMSafety and Efficiency of Site-Specific Integration AAV-rDNA VectorsZhongya Wang, Mark Kay, Markus Grompe.683 4:45 PMFunctional Improvement of LGMD Hamsters by AAV-hMG53-Mediated Sarcolemma RepairBo He, Chunping Qiao, Bin Xiao, Juan Li, Zhenhua Yuan, Christina Mayer, Jianjie Ma,Xiao Xiao.Saturday, May 22 ndOral Abstract Session 435Gene Therapy for Inborn Errors of Metabolism3:00 PM - 5:00 PMRoom: Wilson ABC676 3:00 PMEarly Gestational Gene Transfer with Lentiviral Vector Driven bya Liver Specific Promoter Targets the Fetal Liver and ImprovesPhenotype in a Murine Model of Wilson’s DiseaseJessica L. Roybal, Masayuki Endo, Antoneta Radu, Carlyn Todorow, Philip W. Zoltick,Alan W. Flake.677 3:15 PMA Combination of Pharmacological and Liver-Directed Gene TherapyResults in Long-Term Phenotypic Correction of a Mouse Model ofArgininosuccinic AciduriaPhilippe M. Campeau, Oleg A. Shchelochkov, Sandesh C. Sreenath Nagamani, NicolaBrunetti-Pierri, Donna Palmer, Muralidhar H. Premkumar, Harsha K. Garg, Anilkumar K.Reddy, Yaoping Tang, Nathan S. Bryan, Ayelet Erez, Brendan H. Lee.Oral Abstract Session 436Late Breaking Science3:00 PM - 5:00 PMRoom: Virginia Suite914 3:00 PMPostexposure Protection of Nonhuman Primates against a LethalEbola Virus Challenge by RNA InterferenceMarjorie Robbins, Amy CH Lee, Joan B Geisbert, Anna N Honko, Vandana Sood, Joshua CJohnson, Susan de Jong, Iran Tavakoli, Adam Judge, Thomas W Geisbert, Lisa E Hensley,Ian MacLachlan.915 3:15 PMA Clinical Study to Evaluate the Safety and Efficacy of pGM169/GL67A Administered to the Nose and Lungs of Individuals with CysticFibrosisStephen C Hyde, Jane C Davies, Uta Griesenbach, Tracy Higgins, Eric WFW Alton, AChristopher Boyd, J Alastair Innes, David Porteous, Deborah R Gill.916 3:30 PMLong-Term Safety and Transgene Expression in MonkeysAdministered Lentiviral and AAV Vectors In UteroAF Tarantal, CCI Lee, C Mall, BJ Byrne, DB Kohn.EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010129Abstract DirectorySaturday, May 22, 2010Oral Abstract Session 436 — continuedLate Breaking Science3:00 PM - 5:00 PMRoom: Virginia Suite917 3:45 PMrAAV- Mediated Therapeutic Silencing of miR-122 Leads to Rapid andSignificant Reduction of LDL in DLDR-/-/Apobec1A-/- MiceJun Xie, Jennifer Broderick, Qing Xie, Hongwei Zhang, Ran He, Chengjian Li, Qin Su, LiZhong, Terence R. Flotte, Phillip D. Zamore, Guangping Gao.918 4:00 PMHyperactive Transposons for Genetic Modification of InducedPluripotent and Adult Stem Cells: A Novel Non-Viral Paradigm forCoaxed DifferentiationEyayu Belay, Janka Mátrai, Abel Acosta-Sanchez, Ling Ma, Mattia Quattrocelli, LajosMátés, Pau Sancho-Bru, Martine Geraerts, Bing Yan, Joris Vermeesch, Ermira Samara-Kuko, Zoltán Ivics, Catherine Verfaillie, Maurillio Sampaolesi, Zsuzsanna Izsvák, ThierryVandenDriessche, Marinee K.L. Chuah.919 4:15 PMPromoting the Migration and Integration of Schwann Cells afterTransplantation into Lesioned Spinal Cord by Lentiviral MediatedExpression of Polysialic AcidJuan Luo, Xuenong Bo, Dongsheng Wu, John Yeh, Peter M Richardson, Yi Zhang.920 4:30 PMRescue of the Spinal Muscular Atrophy Phenotype in a Mouse Modelby Early Postnatal Delivery of SMNKevin D Foust, Xueyong Wang, Vicki L McGovern, Lyndsey Braun, Adam K Bevan,Amanda M Haidet, Thanh T Le, Pablo R Morales, Mark M Rich, Arthur H M Burghes,Brian K Kaspar.921 4:45 PMAptamer-Mediated Delivery of siRNAs and miRNA-Based siRNATriggers to the Nucleus of Multiple Cancer Cell TypesJonathan Kotula, Bruce Sullenger.Poster Session III6:00 PM - 8:00 PMRoom: Exhibit Hall CRNA Virus Vectors II684Insights on the Mechanisms of Measles Virus Entry into CellsMatthew K. Ennis, Stephen J. Russell, David Dingli.685The Principal Function of the Lentiviral Central DNA Flap Is DefenseAgainst APOBEC3 Protein RestrictionChunling Hu, Dyana T. Saenz, Hind Fadel, Mary E. Peretz, William Walker, Eric M.Poeschla.686In Vivo Immunization with Integration Deficient Lentiviral VectorsBiliang Hu, Pin Wang.687“Same Day” Ex Vivo Regional Gene Therapy: A Novel Approach ToEnhance Bone RepairMandeep S. Virk, O. Sugiyama, Sang H. Park, Jay R. Lieberman.688The R Peptide Sequence of XMRV Envelope Glycoprotein Determinedthe Pseudotyping Specificity with HIV-1 and MLV VectorsToshie Sakuma, Suk See De Ravin, Harry L. Malech, Yasuhiro Ikeda.689Virus-Receptor Mediated Transduction of Dendritic Cells among RossRiver Virus and Semliki Forest Virus Pseudotyped LentivectorsSteven Froelich, April Tai, Katie Stroup, Adnan Zubair, Pin Wang.690Effect of TLX1 Homeobox Gene Expression on InsertionalImmortalization by an Insulated Self-Inactivating Retroviral VectorLynnsey A. Zweier-Renn, Teresa S. Hawley, Ali Ramezani, Irene Riz, Robert G. Hawley.691Transcriptional Pulsing of Retroviral Transgenes in Mouse EmbryonicStem CellsMandy Y. M. Lo, Akitsu Hotta, Sylvie Rival-Gervier, James Ellis.692The Cellular Fibronectin Matrix Is a Key Factor for the Attachmentof VSV-G Pseudotyped Vector Particles and Its Cell Type SpecificComplexity Provides a Mechanism for Delayed Cell EntryJosha A. Woodward, Amy M. Skinner, Peter Kurre.693Targeting of Lentiviral Vectors and Positioning of Transduced Cells byMagnetic Nanoparticles and Magnetic FieldKatrin Zimmermann, Christina Trueck, Olga Mykhaylyk, Ulrich M. Becher, BernhardGleich, Daniela Wenzel, Bernd Fleischmann, Christian Plank, Alexander Pfeifer.694Pseudotyped Hepatitis C Virus Particle Could Be a Liver Target Bio-MissileXiaojing Lin, Yonghui Zhang, Yue Wang.695Regulation of Cytokine Expression by Lentivirus-Encoded RNAAntagomirsRasmus O. Bak, Line B. Petersen, Brian Moldt, Karin Stenderup, Cecilia Rosada, LarsAagaard, Tomas N. Dam, Jacob G. Mikkelsen.696Effects of Replicators on Retroviral Variegation and ExtinctionMeihong Liu, Maribeth V. Eiden.Saturday, May 22 nd

130American Society of Gene & Cell TherapyAbstract DirectorySaturday, May 22 ndSaturday, May 22, 2010Poster Session III — continued6:00 PM - 8:00 PMRoom: Exhibit Hall CAAV Vectors III697Late Gestation Intrauterine Gene Transfer of AAV9 in Non-HumanPrimates Preferentially Transduces the Central Nervous System,Liver, Skeletal and Cardiac MusculatureC. N. Mattar, N. Johana, A. Fisk, A. Biswas, J. Lu, M. H. Tan, L. G. Tan, A. Rahim, S.Waddington, M. Choolani, J. Chan.698Integrin-Linked Endocytosis Directs AAV2 and AAV1 to a HighlyEfficient Transduction PathwayPaul M. Kaminsky, Nicholas W. Keiser, John F. Engelhardt.699Computationally-Guided Rational Design of Tropism-Modified AAVVectorsAdam S. Davis, William C. Ray, Thais Federici, Nicholas M. Boulis, Jeffrey S. Bartlett.700Identification of Human Hepatocyte Growth Factor Receptor as aCellular Receptor/Co-Receptor for AAV3Chen Ling, Yuan Lu, Jasmine K. Kalsi, Giridhara R. Jayandharan, Binbin Cheng, SamanthaW. Y. Gee, Katherine E. McGoogan, Li Zhong, Arun Srivastava.701Rapid Transgene Expression and Long-Term Phenotypic Correctionof a Lethal Mouse Model of Methylmalonic Acidemia Using rAAV9-Mediated Gene DeliveryJulien S. Senac, Randy J. Chandler, Charles P. Venditti.702Widespread Transduction of Brain Parenchyma after IntraventricularInjection of AAV9Annagiusi Gargiulo, Enrico M. Surace.703AAV1.9-3 Exhibiting Significantly Impaired Infectivity andSubstantially Delayed Blood Clearance, Is a Novel DetargetedPlatform of AAV Random Peptide Display LibrariesKei Adachi, Nicole M. Kotchey, Kimimasa Tobita, Hiroyuki Nakai.704Development of the D[+]-Sequence-Deleted ssAAV2 Vectors:Enhanced Transgene Expression In Vitro and In VivoChen Ling, Giridhara R. Jayandharan, Baozheng Li, Yuan Lu, Wenqin Ma, Arun Srivastava.705Influence of Murine Parvovirus on Adeno-Associated Virus Vector-Related Expression in Murine ModelsSara A. Collins, Gerald C. O’Sullivan, Patrick T. Harrison, Martina F. Scallan, MarkTangney.706Involvement of the Glucocorticoid Receptor Signaling in AAV2 Vector-Mediated Transgene ExpressionYuan Lu, Chen Ling, Giridhara R. Jayandharan, Angela E. Rivers, Arun Srivastava.707AAV9-Mediated Catalase Expression in Mitochondria ImprovesExercise Performance in mdx MiceDejia Li, Dongsheng Duan.708Development of a Liver Specific Tet-On Inducible System for AAVVectorsLucia Vanrell, Laura Blanco, Lilianne Tenenbaum, Jesus Prieto, Gloria González-Aseguinolaza.709Intracortical Delivery of an Adeno-Associated Viral Vector Expressingthe Glutamate Transporter (GLT1) Decreases Stroke-InducedExtracellular Glutamate Overflow and Cerebral Infarction afterTransient Middle Cerebral Artery Occlusion in RatsBrandon K. Harvey, Mikko T. Airavaara, Jason Hinzman, Matthew J. Chiocco, Hui Shen,Douglas B. Howard, Greg A. Gerhardt, Barry J. Hoffer, Yun Wang.710The Potential Role of Chromatin Structure in Adeno-Associated VirusType 2 Locus-Specific Integration at AAVS1Victor J. McAlister, Roland A. Owens.711Augmentation of Traditional Ad/AAV Helper Plasmids with HPV E1Increases rAAV DNA Replication and Virus Production in 293 CellsSarmistha Bandyopadhyay, Maohua Cao, Yong Liu, Paul L. Hermonat.Adenovirus and Other DNA Virus Vectors III712Hexon-Modifications of hAd5 Based Helper-Virus for High-CapacityAdenoviral Vector Production and Limitations Imposed by HVR-Exchanges Utilizing Serotype SwitchMartin A. Hausl, Zsolt Ruzsics, Anja Ehrhardt.713Use of Cell-Penetrating Peptides To Induce a Bystander EffectYing Shen, William Yu, John G. Hay, Harald Sauthoff.714Highly Sensitive Detection of Prostate Cancer Cells In Vivo by a DualAdenoviral TSTA Trans-Amplification SystemMakoto Sato, Frédéric Pouliot, Steve Huyn, Lily Wu.715Coagulation Factor X-Mediated Adenoviral Transduction Is Dependenton Heparan Sulfate Proteoglycan SulfationAngela C. Bradshaw, Alan L. Parker, Stuart A. Nicklin, John H. McVey, Andrew H. Baker.EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010131Abstract DirectorySaturday, May 22, 2010Poster Session III — continued6:00 PM - 8:00 PMRoom: Exhibit Hall CAdenovirus and Other DNA Virus Vectors III716Towards the Generation of a Baculovirus Display Library for CellTargetingMarcel Westenberg, Helen M. Soedling, Linda J. Nicholson, Derek A. Mann, Colin T.Dolphin.717Broad Spectrum Activity of the HSV-2 Vector DRR EnhancesNeuroprotection and Includes Crosstalk between Neurons and GlialCellsJennifer M. Laing, Laure Aurelian.718Enhanced Transduction and Replication of Fiber-Modified Adenovirusin Murine Primary T CellsSadhak Sengupta, Ilya V. Ulasov, Atique U. Ahmed, Maciej S. Lesniak.719Cloning of the Human Herpesvirus-6A (HHV-6A) Genome into theBacterial Artificial Chromosomes (BACs) towards the Creation ofHelper-Less Amplicon Vectors for Potential Use in Lymphocyte GeneTherapy and VaccinationNiza Frenkel, Ronen Borenstein, Haim Zeigerman, Adi Museri, Pnina Schlesinger.720Adenovirus-Mediated Decorin Expression Induces Cell Death throughActivation of p53 and Mitochondrial ApoptosisA-Rum Yoon, Jung-Sun Lee, Chae-Ok Yun.721PEG-Modified Adenovirus Conjugated with Herceptin ImprovesTherapeutic Value by Active Targeting through Her2/neu with anEnhanced Safety ProfileJoung-Woo Choi.722Study on Testing Method for Adeno-Associated Virus (AAV) ofAdventitious VirusYejin Choi, Nam Hee Kim, Keum S. Choi, Keerang Park, Younjoo Park.723Ad5-Ad48 Hexon Hypervariable Region Substitutions Affect ViralBiodistribution and Inflammatory Responses In VivoLynda Coughlan, Angela Bradshaw, Laura Denby, Stuart A. Nicklin, Jerome Custers, Nicovan Rooijen, Dan H. Barouch, Andrew H. Baker.724Evaluation of a Porcine Adenovirus 3 Vector as a Post-ExposureVaccine CandidateAmi Patel, Suresk K. Tikoo, Gary P. Kobinger.725The Knob Domain Replacement Strategy Is Broadly Applicable to aWide Variety of Adenovirus Fiber ProteinsGalina Mikheeva, Natalya Belousova, Victor Krasnykh.DNA Vectorology & Gene Targeting726Transcriptional Repression of Transgenes Delivered by SleepingBeauty, piggyBac and Tol2 DNA Transposon VectorsNynne Sharma, Rasmus O. Bak, Nicklas H. Staunstrup, Gernot Wolf, Jacob G. Mikkelsen.727Duration of Expression from CpG-Free Plasmids FollowingHydrodynamic Delivery to the MouseIan A. Pringle, Mary M. Connolly, Anna E. Lawton, Lee A. Davies, Stephen C. Hyde,Deborah R. Gill.728A Liver-Specific Promoter Enhances Expression of alpha-L-Iduronidasein Sleeping Beauty Transposon-Mediated Gene Therapy of MurineMPS IElena L. Aronovich, Jason B. Bell, Brenda L. Koniar, Perry B. Hackett.729New Generation, S/MAR Based, Episomal Vectors with HighPotential for Gene Transfer into Hematopoietic Progenitor CellsEleana Stavrou, Vassileios Lazaris, Eirini Papapetrou, Aristeidis Giannakopoulos,Dimitra Kokkinou, Louiza Toutouna, Alexandros Spyridonidis, Nikolas Zoumbos, AglaiaAthanassiadou.730High-Yield, Non-Viral Production of Engineered Cells throughSleeping Beauty Transposon-Mediated Gene Integration Coupled withSelective AmplificationNataly A. Kacherovsky, Maja Zavaljevski, Carl A. Blau, Cecilia M. Giachelli, Suzie H. Pun.731A Combinatorial Approach for Targeted, Systemic Delivery UsingSmall Molecules and Reversible Masking to Bypass Non-SpecificUptake In VivoNancy S. Templeton, Qiaoyun Shin, Andrew T. Nguyen, Yu Angell, Defeng Deng, Chang-Rim Na, Kevin Burgess, David D. Roberts, F. C. Brunicardi, Phillip B. Maples, JohnNemunaitis.732Using Helper Virus-Free Packaged HSV-1/EBV Hybrid Amplicons ToInduce Directed Cell Motility toward SDF-1aYasser M. El-Sherbini, Mark Stevenson, Richard Wade-Martins, Len W. Seymour.733A Novel System for the Evaluation of Genotoxicity for Gene TherapyVectorsJun Zhan, Matthew M. Wielgosz, John Gray, Arthur W. Nienhuis.Saturday, May 22 nd

132American Society of Gene & Cell TherapyAbstract DirectorySaturday, May 22 ndSaturday, May 22, 2010Poster Session III — continued6:00 PM - 8:00 PMRoom: Exhibit Hall CDNA Vectorology & Gene Targeting734A Liver-Directed Targeting Tether Vector System To Increase Uptakein Liver CellsJason B. Bell, Erik Olson, R. Scott McIvor, Perry B. Hackett.735Cells Labeled with Fatty Acid-Oligonucleotide Conjugates asPotentially Suitable for Tissue EngineeringGalina E. Pozmogova, Marina A. Zaitseva, Andrey N. Chuvilin, Grigory G. Borisenko.736An Enhanced Non-Viral Expression Vector (EEV) – For CancerTreatmentPatrick F. Forde, Mira Sadadcharam, Marcel De Kruijf, Slawomir P. Salwa, Michael G.Bourke, Gerald C. O’Sullivan, Declan M. Soden.737Development of Post-Translational Tumor-Targeted-Cytokine Vectorfor Systemic Treatment of Malignant DiseaseJeffry J. Cutrera, Denada Dibra, Xuexing Xia, Shulin Li.738Improved Antibiotic-Free Plasmid Vector Design by Incorporation ofTransient Expression EnhancersJeremy M. Luke, Justin M. Vincent, Clague P. Hodgson, James A. Williams.739Genomic DNA Reduction for Therapeutic DNA ManufactureYing Cai, Debra Bailey, Reto P. Bazzani, Henry Hebel, Stephen C. Hyde, StephenRodriguez, Deborah R. Gill.740Preclinical Efficacy and Safety of Electroporation-Mediated Deliveryof a Plasmid Vector Manufactured in the Absence of AntibioticSelectionKaren E. Dolter, Cedric Y. Szpirer, Philippe Gabant, Drew Hannaman, Claire F. Evans.741Hepatic Stellate Cell-Specific TGF-b1 Gene Silencing for Treating LiverFibrosisNingning Yang, Ram I. Mahato.Chemical and Molecular Conjugates III742Nuclear Enclosure of Nanospheres in Artificial Nuclei and in LivingCellsNathalie Symens, Katrien Remaut, Jo Demeester, Stefaan C. De Smedt.743Analysis of Intracellular Trafficking of MPC-Coated MultifunctionalEnvelope-Type Nano Device (MPC-MEND) in Isolated HepatocyteMasami Ukawa, Hidetaka Akita, Tomoya Masuda, Yasuhiro Hayashi, Tomohiro Konno,Kazuhiko Ishihara, Hideyoshi Harashima.744Photo-Activated Release of DNA from Liposome ComplexesCaroline M. LaManna, Jiazuo H. Feng, Hrvoje Lusic, Mark W. Grinstaff.745A Novel Cationic Lipophosphoramide with Di-Unsaturated LipidChains: Synthesis, Physico-Chemical Properties, and TransfectionActivitiesTony Le Gall, Damien Loiseau, Erwan Picquet, Nathalie Carmoy, Jean Jacques Yaouanc,Laure Burel Deschamps, Pascal Delépine, Philippe Giamarchi, Paul Alain Jaffrès, PierreLehn, Tristan Montier.746Modifying DNA Nanoparticles with Biotin for Versatile LigandSubstitutionWenchao Sun, Pamela B. Davis.747An Integrative Approach To Monitor Gene Delivery to AirwayEpithelium by Nanocomplex Vectors and Radioimaging AgentsMaria D. I. Manunta, Aristides Tagalakis, Christopher O’Callaghan, Stephen L. Hart.748Development of Small, Homogenous Non-Viral Gene Vector UsingMono-Cationic DetergentsRyosuke Suzuki, Yuma Yamada, Hideyoshi Harashima.749Development of DNA Complex-Releasing Systems UsingBiodegradable Apatite Cement and Therapeutic Effect in Tumor ModelMiceTomoko Ito, Yoshiyuki Koyama, Makoto Otsuka.750Investigation of Cross-Linking Peptides as Gene Delivery VectorsAnton V. Kiselev, Anna A. Egorova, Arto O. Urtti, Vladislav S. Baranov.751Rapid and Highly Efficient Magnetofection of IL-10 to ExtremelySusceptible Vascular Endothelial Cells Using Hybrid Iron Oxide-PEIConjugateYong Sook Kim, In-Kyu Park, Jin Sook Kwon, Myung Ho Jeong, Youngkeun Ahn.752Cocaine Conjugated to Disrupted Adenovirus – A Synthetic/Viral Protein Hybrid Strategy To Elicit High Titers Against Non-Immunogenic Addictive Small MoleculesBishnu P. De, Martin J. Hicks, Jonathan B. Rosenberg, Stefan Worgall, Stephen M.Kaminsky, Amira Y. Moreno, Kim D. Janda, Ronald G. Crystal.753Bisphosphonate-Mediated Gene-Eluting Metal Stent as Gene VectorDelivery Using Antibody for Localized Gene DeliveryYong Wang, Cunxian Song, Robert J. Levy.EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010133Abstract DirectorySaturday, May 22, 2010Poster Session III — continued6:00 PM - 8:00 PMRoom: Exhibit Hall CChemical and Molecular Conjugates III754Optimization of Sendai F/HN Viroplexes for Efficient Transfection ofPlasmid DNA and siRNA to Suspension CellsJung Seok Kim, Yeon Kyung Lee, Jin Ee Baek, Sang Il Park, Hwa Yeon Jeong, Hong SungKim, Keun Sik Kim, Yong Serk Park.755Comparative Evaluation of Disulfide-Linked and Hydrophobically-Modified PEI for Plasmid Delivery In VitroK. C. B. Remant, Breanne Landry, Hasan Uludag.756Linear Polyethylenimine Prepared by Partial Acid Hydrolysis of Poly(2-ethyl-2-oxazoline) for DNA and siRNA Delivery In VitroJulio C. Fernandes, Xingping Qiu, Francoise M. Winnik, Mohamed Benderdour, XiaolingZhang, Kerong Dai, Qin Shi.757Impact of Counterion and Hydrophobic Anchor on PhysicochemicalCharacteristics and Transfection Efficiency for a Series of PyridiniumCationic Lipid-Based LipoplexesSushma Savarala, Stephanie L. Wunder, Marc A. Ilies.Genetic and Metabolic Diseases Gene & Cell Therapy III758AAV-Mediated Liver Gene Transfer Results in Long-Term Expressionof Therapeutic Levels of ARSB in MPS VI CatsGabriella Cotugno, Patrizia Annunziata, Anita Capalbo, Thomas O’Malley, PatriciaO’Donnell, Fabio Russo, Elvira De Leonibus, Mark Haskins, Alberto Auricchio.759Beta-Glucuronidase Expressed from AAV Is Poorly Modified withMannose-6-Phosphate Residues and Fails to Completely CorrectMucopolysaccharidosis VII in DogsGuangping Gao, Peter L. Bell, Mark E. Haskins, Lisa A. Kisling, Richard Steet, Luk H.Vandenberghe, Hongwei Yu, Julio C. Sanmiguel, James M. Wilson.760Gene Transfer To Induce Cellular Reprogramming for the Treatment ofDiabetesNeil Phillips, Markus Grompe, Mark A. Kay.761Salivary Gland hPTH Gene Transfer: Interesting PossibilitiesJanik Adriaansen, Paola Perez, Changyu Zheng, Michael T. Collins, Bruce J. Baum.762Efficient Gene Transfer to the Pancreas Using ssAAV for Preventionof Type 1 DiabetesEduard Ayuso, Veronica Jimenez, Judith Agudo, Ariana Salavert, Sergio Muñoz, AlbaCasellas, Merce Obach, Maria Molas, Marta Moya, Xavier Leon, Jesus Ruberte, FatimaBosch.763Tolerance Induction to Coagulation Factor IX Using Gene ModifiedPrimary B CellsBabak Moghimi, Irene Zolotukhin, Ou Cao.764 (Moved to Poster Session II after Abstract 422)Microporous Polymer Scaffolds for Islet TransplantationRomie F. Gibly, Lonnie D. Shea.765AAV2- and AAV9 -Mediated Gene Transfer of LDL Receptor toHypercholesterolemic WHHL RabbitsElisa Vähäkangas, Anniina Laurema, Atsushi Miyanohara, Seppo Ylä-Herttuala.766Hairpin Ribozymes Encoded in Adenoviral Vectors Reduce Drinking inAlcohol Dependent RatsAmalia Sapag, Thergiory Irrazábal, María Elena Quintanilla, Lutske Tampier.767Sustained Therapeutic Levels of FVIII Activity from Lentivirally-Engineered Blood Outgrowth Endothelial Cells Requires Cell Stabilityand Augmented AngiogenesisHideto Matsui, Margareth Ozelo, Andrea Labelle, Carol Hegadorn, Patrick Thompson,Erin Burnnet, Christine Hough, David Lillicrap.768Effects of Neonatal Intracranial AAV and Systemic Lentiviral GeneTherapy in Sanfilippo Syndrome Type B MiceCoy D. Heldermon, Elizabeth Qin, Kevin K. Ohlemiller, Erik Herzog, Carole Vogler, DavidF. Wozniak, Mark S. Sands.769Laminin-111: A Highly Potent Therapeutic Agent To Treat DuchenneMuscular DystrophySebastien Goudenege, Yann Lamarre, Nicolas Dumont, Joel Rousseau, Skuk Daniel,Jacques P. Tremblay.770Layered Scaffolds for Islet Transplantation and Gene DeliveryJohn G. Graham, Lonnie D. Shea.771Lentiviral Vector Correction of Fabry Disease Encompassing a CellFate Control Safety ElementMatthew D. Scaife, Sean P. Devine, Anton Neschadim, Natalia A. Pacienza, Jeffrey A.Medin.772Wolman Disease (LIPA p.G87V) Genotype Frequency in Patients ofIranian-Jewish DescentYadira Valles-Ayoub, Daniel No, Saghi Esfandiarifard, Zeshan Khokher, Chai Saechao,Marvin Pietruszka, Daniel Darvish.Saturday, May 22 nd

134American Society of Gene & Cell TherapyAbstract DirectorySaturday, May 22 ndSaturday, May 22, 2010Poster Session III — continued6:00 PM - 8:00 PMRoom: Exhibit Hall CNeurodegenerative Disorders, Spinal Cord and Trauma773Delayed Inhibition of Soluble Tumor Necrosis Factor Signaling Blocksthe Progressive Phase of Dopaminergic Neuron Death in a Rat Modelof Parkinson’s DiseaseAshley S. Harms, Kelly M. Ruhn, Steve Varghese, Isaac Trevino, Malu G. Tansey.774Identification and Analysis of a Novel g-Secretase Inhibitory GeneHiroki Hayashi, Hironori Nakagami, Nobutaka Koibuchi, Munehisa Shimamura, YasufumiKaneda.775Effects of Alpha 7 Nicotinic Receptor Gene Delivery on ProcessesUnderlying Cell Viability and Cell DifferentiationYan Ren, Lin Zhang, Edwin M. Meyer, Jeffrey A. Hughes, Sihong Song.776Delivery of hGDNF to Brain Using DNA Nanoparticles:Neuroprotection of the Nigrostriatal PathwayDavid M. Yurek, Anita M. Fletcher, Linas Padegimas, Tomasz H. Kowalczyk, Mark J.Cooper.777ProSavin, a Gene Therapy for Parkinson’s DiseaseBechir Jarraya, Helene Lepetit, Scott Ralph, James Miskin, Jean-Marc Gurruchaga, MariaVinti, Gilles Fenelon, Pierre Brugiere, K. Abay, I. Gabriel, Sabrina Boulet, Caroline Jan,Susan Kingsman, P. Cesaro, Philippe Hantraye, Philippe Remy, Kyriacos Mitrophanous,Stephane Palfi.778Primate Hippocampal Gene Delivery Via Frameless StereotaxisCary H. Leung, Michele A. Kliem, Brooke R. Snyder, Thais Federici, Thomas J. McKown,Scott W. J. McPhee, Nicholas M. Boulis.779Delivery Co-Interventions in Gene Transfer and Cell Transplantation:A Meta-Analysis of Surgical Risk for Trials Involving Inoculation toDeep Brain StructuresJonathan Kimmelman, Katherine Duckworth, Tim Ramsay, Marina Emborg, Tiffini Voss.780Modification of the Inhibitory Environment of Spinal Cord Injury byLentiviral Vector Containing NT-3 and shRNA for NG2Eleanor M. Donnelly, Nicolas N. Madigan, Gemma E. Rooney, Anthony J. Windebank,Timothy O’Brien, Siobhan S. McMahon.781HSV Gene Transfer of a Poreless TRPV1 Receptor Reduces Pain-Related Behavior in RodentsJames R. Goss, William F. Goins, Rahul Srinivasan, Joseph C. Glorioso.782A Comparison of AAV Serotypes and Routes of Administration forDelivery to the Spinal CordBrooke R. Snyder, Thais Federici, Eric Quach, Steven Gray, Cary H. Leung, Nicholas M.Boulis.783Engineered Zinc Finger Protein Improves Microvascular Recovery,Neuronal Sparing and Functional Recovery in Modeled TraumaticBrain Injury in RatsEugene Park, Ishita Siddiq, Elaine Liu, S. Kaye Spratt, Richard Surosky, Gary Lee, DaleAndo, Marty Giedlin, Andrew J. Baker.Musculo-skeletal Gene & Cell Therapy III784Blocking the Myostatin Signal Improves the Success of HumanMyoblast Transplantation in Dystrophic MiceRaouia Fakhfakh, Annick Michaud, Jacques P. Tremblay.785High Force Myosin Correlated with the Early Degeneration of JawClosing Muscle in the GRMD Model of DMDAndrew F. Mead, Alock Malik, Mihail Petrov, Martin Childers, Marilyn Mitchell, JanetBogan, Joe Kornegay, Brittani Nickens, Hansell Stedman.786Comparison Studies of rAAV6 Transduction Efficiency in Adult andAged MusclesPatryk Konieczny, James M. Allen, Eric Finn, Jeffrey S. Chamberlain.787Gene Transfer of Signals Critical for Allograft Healing UsingImmobilized Freeze Dried Adeno-Associated Viral VectorsMette Koefoed, Alexandra G. Pedersen, Michael Ulrich-Vinther, Thomas G. Jensen, KjeldSoballe.788Rescue from Respiratory Dysfunction by Transduction of Full-LengthDystrophin to Diaphragm Via the Peritoneal Cavity in MuscularDystrophy MouseIshizaki Masatoshi, Yasushi Maeda, En Kimura, Makoto Uchino.789Restoration of Wild-Type DMD mRNA in an Immortalized HumanFibroblast Line from an Exon 8-9 Duplicated DMD PatientLing Zhao, Gillian Butler-Browne, Vincent Mouly, Soraya Chaouch, Kamel Mamchaoui,Steve D. Wilton, Kevin M. Flanigan.790Expression of Micro-Dystrophin and Full-Length Dystrophin in Mouseand Dog MusclesChristophe Pichavant, Pierre Chapdelaine, Joe N. Kornegay, João C. S. Bizario, XiaoXiao, Jacques P. Tremblay.EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010135Abstract DirectorySaturday, May 22, 2010Poster Session III — continued6:00 PM - 8:00 PMRoom: Exhibit Hall CMusculo-skeletal Gene & Cell Therapy III791A Comparison of Adeno-Associated Virus Mediated Gene Transferinto Healthy and Dystrophin-Deficient Skeletal MusclesGilles Moulay, Carole Masurier, Pascal Bigey, Daniel Scherman, Antoine Kichler.792In Vivo Reprogramming into the Myogenic Lineage and ImprovingEngraftment in the mdx Mouse Model of DMDLindsey A. Muir, Jeffrey S. Chamberlain.793Gene Transfer-Driven Inhibition of Cardiac Ankyrin Repeat Protein asa Potential Therapy for the Correction of Muscular DystrophiesNathalie F. Danièle, Laurence Suel-Petat, Isabelle Richard.794Background Strain and Natural Selection Improves Survival of HIBMMouse ModelYadira Valles-Ayoub, Zeshan Khokher, Arman Haghighatgoo, Daniel No, SaghiEsfandiarifard, Chai Saechao, Jennifer Kay, Christopher Creencia, Sheila Darvish, DanielDarvish.795Combining Stem Cells and Exon Skipping Approach To Treat MuscularDystrophiesMirella Meregalli, Daniele Parolini, Andrea Farini, Marzia Belicchi, Giuseppe D’Antona,Simona Maciotta, Paola Razini, Alberto Lerario, Serena Bonfiglio, Roberto Bottinelli, LuisGarcia, Nereo Bresolin, Yvan Torrente.796Gene and Cell Therapy Approaches Tto Treating the DysferlinopathiesBradley A. Williams, Nilah Monnier, Douglas E. Albrecht, Nupur Garg, Laura E. Rufibach,Esther Hwang, Angela Salerno, Plavi Mittal.Infectious Diseases and Vaccines: Non-Vaccine Related GeneTransfer Research797Delineation of RNA Antisense env Effects on HIV QuasispeciesRecovered from Lexgenleucel-T Treated Subjects: Influences ofSequence Similarity of the RNA Antisense with the Targeted HIV envTranscript and VRX496-Modified Cell PersistenceAlexander Pasternak, Nikolay Korokhov, Vladimir Lukashov, Laurent M. Humeau.798Assessing Preclinical Safety of a CCR5-Specific Zinc Finger Nucleasein Human CD4+T Cells Using the NSG Immunodeficient Mouse ModelS. Kaye Spratt, Marty Giedlin, Richard Carroll, Shuguang Jiang, Dawn Maier, GwendolynBinder-Scholl, Gary Lee, Lynn Truong, Bruce Levine, Michael Holmes, Philip Gregory, CarlJune, Dale Ando.799Multivirus-Specific T Cell Immunotherapy To Prevent or TreatInfections of Allogeneic Stem Cell Transplant RecipientsAnn M. Leen, Ulrike Gerdemann, Carlos A. Ramos, Tamara Tripic, Malcolm K. Brenner,Cliona M. Rooney, Juan F. Vera, Helen E. Heslop.800Inhibition of HIV-1 Replication in VRX496-Modified CD4 T Cells:Importance of Cytoplasmic dsRNA ComponentsRandall Merling, Brit J. Hart, Ziping C. Chen, Laurent M. Humeau, Nikolay Korokhov.801Engineering Resistance to CXCR4-Tropic HIV: A Cutting EdgeApproachCraig B. Wilen, Michael C. Holmes, Jianbin Wang, Philip D. Gregory, Carl H. June, RobertW. Doms.802Development of an Unbiased Method for Characterizing ViralPopulations Using Next Generation Sequencing TechnologyStephanie M. Willerth, Helder L. Pedro, Laurent M. Humeau, Adam P. Arkin, David V.Schaffer.803Long Term Persistence of VRX496-Modified CD4+ T LymphocytesFollowing Lexgenleucel-T Infusions for the Treatment of HIV/AIDS:Results from a Phase 2 Clinical TrialLaurent M. Humeau, Kris Andre, Karen Bengtson, Shuyuan Zhang, Gerard McGarrity,Tessio Rebello.804Generation of Restriction Factor-Transgenic Cats Using LentiviralTransgenesisPimprapar Wongsrikeao, Dyana T. Saenz, Thomas A. Rinkoski, Takeshige Otoi, Eric M.Poeschla.805Combinatorial Latency Reactivation for HIV-1 Subtypes and VariantsJohn C. Burnett, John J. Rossi, Kwang-il Kim, Adam P. Arkin, David V. Schaffer.806Highly Efficient Expression and Purification of Hepatitis C Virus CoreProtein in E.coliYixin Bian, Guozhen Qiu, Tingting Li, Zixuan Chen, Wenjing Wang, Chengyao Li.807Molecular Epidemiology of HCV Infection among Recovery andChronic Blood Donors in Guangdong, ChinaTingting Li, Jinfeng Zeng, Zixuan Chen, Lifang Shuai, Anqi Wang, Chengyao Li.Saturday, May 22 nd

136American Society of Gene & Cell TherapyAbstract DirectorySaturday, May 22 ndSaturday, May 22, 2010Poster Session III — continued6:00 PM - 8:00 PMRoom: Exhibit Hall CInfectious Diseases and Vaccines: Non-Vaccine Related GeneTransfer Research808Occult Hepatitis B Virus Infection in Shenzhen, ChinaXin Zheng, Yixin Bian, Ling Zhang, Wenjing Wang, Lifang Shuai, Anqi Wang, Jean-PierreAllain, Daniel Candotti, Chengyao Li.Cancer – Immunotherapy III809Time for TEA: T Cells Expanded on Artificial Antigen Presenting Cells?Hillary N. Gibbons, Carrie Yuen, Sergio Giralt, Carl H. June, Laurence J. N. Cooper.810Oxaliplatin Increases the Antitumor Effect of Vector-DeliveredInterleukin-12 Expression in a Murine Model of Hepatic ColorectalCancer MetastasesManuela Gonzalez-Aparicio, Itsaso Mauleon, Pilar Alzuguren, Sandra Hervas-Stubbs,Uxua Manchengo, Julien Crettaz, Gloria González-Aseguinolaza, Jose Medina-Echeverz,Pedro Berraondo, Jesus Prieto, Ruben Hernandez-Alcoceba.811Optimizing Dendritic Cell Vaccination by Combination with OncolyticAdenovirus Coexpressing Interleukin-12 and Granulocyte-Macrophage Colony Stimulating FactorSong-Nan Zhang, Jing-Hua Huang, Ji Young Yoo, Kyung-Ju Choi, Chae-Ok Yun.812Bacterial Vector Mediated Vaccination for Prostate CancerGarrett Casey, Sarfraz Ahmad, Michelle Cronin, Simon Rajendran, Mark Tangney, GeraldC. O’Sullivan.813Evaluation of Long-Term Transgene Expression in piggyBac-ModifiedHuman T LymphocytesYozo Nakazawa, Sunandan Saha, Daniel Galvan, Cliona M. Rooney, Matthew H. Wilson.814Engineered Drug Resistant Immunocompetent Cell Therapy forNeuroblastomaAnindya Dasgupta, David McCarty, H. Trent Spencer.815Genetically Mediated Constitutive Expression of CD40L by T CellsWill Induce Enhanced Immunogenicity of B-Cell MalignanciesKevin J. Curran, Raymond Yeh, Beatrijs Seinstra, Yan Nikhamin, Yelena Usachenko,Renier J. Brentjens.816Tumor Antigen Delivery to Secondary Lymphoid Organs byInterleukin-12 Gene Modified T CellsAdham S. Bear, Xiatong Song, Meghan E. Turnis, Stephen M. Gotschalk, Cliona M.Rooney, Aaron E. Foster.817Pluronic Based Formulations Are Promising Anticancer DNA VaccinesCaroline Roques, Zagit Gaymalov, Jedd D. Wolchok, Alexander V. Kabanov.818Efficient Induction of Humoral and Cellular Immune ResponsesAgainst Her-2/neu by Combination of Naked DNA and AdenoviralVectors Expressing Genetically Engineered Her-2/neuJae-Gyun Jeong, Dong-Sik Kim, Sung-Won Lim, Kyu-Woong Shim, Hwang-Jae Lee, Sung-Min Oh, Jin-A Chae, Yeon-Sook Cha, Seong-Hyun Ho, Youngtae Hong, Woong Hahn,Sujeong Kim, Jong-Mook Kim, Seungshin Yu, Chang-Yuil Kang, Sunyoung Kim.819Autocrine, Not Paracrine, Interferon-Gamma Gene Delivery EnhancesEx Vivo Antigen-Specific Cytotoxic T Lymphocyte Stimulation andKillingDazhi Zhang, Liu Yong, Chang Xuan You, Rongcheng Lou, Paul L. Hermonat.820Potent Transfer of Human CD40L to Chronic Myeloid Leukemia StemCells Via an AdCD40L Genetically Engineered Bystander Cell LineLisa H. Christiansson, Lina Liljenfeldt, Bengt Simonsson, Ulla Olsson-Strömberg, AngelicaS. I. Loskog.822Preclinical Efficacy Data of MGN1601, a Tumor Vaccine Comprising4-Fold Gene-Modified and Irradiated Allogeneic Tumor Cells inCombination with a DNA-Based Immunomodulator for the Treatmentof Metastatic Renal CarcinomaBaerbel Volz, Manuel Schmidt, Kerstin Kapp, Matthias Schroff, Marina Tschaika,Burghardt Wittig.823Electrically Mediated Delivery of Plasmid DNA-Encoding Cytokines forthe Generation of an Enhanced Immune Response Against MelanomaBernadette Marerro, Shawna Shirley, Loree Heller, Richard Heller.824Cytokine-Based Log-Scale Expansion of Functional Human DendriticCellsYui Harada, Yasuji Ueda, Hiroaki Kinoh, Aki Furuya, Makoto Inoue, Mamoru Hasegawa,Tomohiko Ichikawa, Yoshikazu Yonemitsu.825Small Plasmid/PEI/Anionic Polysaccharide Ternary ComplexParticles: Toxicity and Animal Clinical StudyYoshiyuki Koyama, Masahiko Tojyo, Chieko Yoshihara, Katsuyuki Hamada, Tomoko Ito.826Imiquimod, a TLR7 Agonist, Delays Brain Tumor Growth throughSuppression of Treg in BrainZhengming Xiong, Shoko Toma, John Ohlfest.EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010137Abstract DirectorySaturday, May 22, 2010Poster Session III — continued6:00 PM - 8:00 PMRoom: Exhibit Hall CCancer – Immunotherapy III827Strategy Escalation: An Emerging Paradigm for Safe ClinicalDevelopment of T Cell Gene TherapiesR. P. Junghans.Cancer-Oncolytic Viruses III828Combination of Promoter and microRNA Detargeting Is GreatlyAdvantageous in Attenuation of Adenoviral Replication in HepaticCellsJustyna Leja, Berith Nilsson, Di Yu, Magnus Essand.829Combining Oncolytic Herpes Simplex Virus and Chemotherapy: G47Dand Temozolomide Synergize in Killing Glioma Stem CellsRyuichi Kanai, Hiroaki Wakimoto, Robert L. Martuza, Samuel D. Rabkin.830Transcriptional Targeting of an Oncolytic HSV-1 to Midkine-PositiveTumorsArturo R. Maldonado, Chuck Klanke, Anil G. Jegga, Bruce J. Aronow, Yonatan Y. Mahller,Timothy P. Cripe, Timothy M. Crombleholme.831Preclinical Studies Support the Efficacy of Prodrug Activator GeneTransfer in Experimental Glioma Models by Enhanced Replication-Competent Retrovirus VectorAkihito Inagaki, Kei Hiraoka, Christopher R. Logg, Hiroshi Matsumoto, Joan Robbins,Omar Perez, Harry Gruber, Douglas Jolly, Noriyuki Kasahara.832Intrapleural Administration of Third Generation Oncolytic HSV-1 (G47D) Is Highly Efficacious in Orthotopic Malignant PleuralMesothelioma ModelsMasamichi Takahashi, Yasushi Ino, Nobuhito Saito, Tomoki Todo.833Engineered Measles Viruses for Oncolytic Therapy of PancreaticCancerSascha Bossow, Christian Grossardt, Stefanie Sawall, Christoph Springfeld, AchimTemme, Roberto Cattaneo, Christof von Kalle, Guy Ungerechts.834Incorporation of a Mutated E1A and a Chimeric 5/3 Fiber Improvedthe Therapeutic Efficacy of a Novel CRAd (Ad-F512) on DisseminatedOvarian CancerVeronica M. Lopez, Angel A. Rivera, Lorena Benedetti, Diego L. Viale, Kristopher J.Kimball, Minghui Wang, Alicia J. Bravo, Christine Dorvault, Joanne Douglas, Zeng B. Zhu,Ronald D. Alvarez, David T. Curiel, Osvaldo L. Podhajcer.835Inhibition of Autophagy Has Negative Impact on Virus ProductionIlya V. Ulasov, Atique U. Ahmed, Bart Thaci, Natalya V. Kaverina, Maciej S. Lesniak.836Armed and Transcriptionally Driven Oncolytic HSV-1 EnhancesAntitumor Efficacy In Vitro and In VivoJi-Young Yoo, Amy Haseley, Anna Bratasz, Kimerly Powell, Balveen Kaur.837Determining Adenovirus Titers Following Extraction of the Virus fromTumors in the Presence of Anti-Adenovirus AntibodiesDebanjan Dhar, Karoly Toth, William S. M. Wold.838 Abstract Withdrawn839The Use of Third Generation Oncolytic HSV-1 Expressing Luciferasefor Demonstration of Real-Time Biodistribution and DynamicsYihan Wu, Yasushi Ino, Tomoki Todo.840Highly Attenuated Vaccinia Virus as a Potential Oncolytic Agent forCancer VirotherapyTakafumi Nakamura, Minoru Kidokoro, Mina Hikichi, Hisatoshi Shida, Hideaki Tahara.841Enhanced Tumor Killing by a Mortalin Targeting Modified OncolyticAdenovirusJung-Sun Lee, Ji Young Yoo, Jihoon Ryu, Tomoko Yaguchi, Sunil C. Kaul, Renu Wadhwa,Chae-Ok Yun.842Increased Oncolytic Ability of a Double RGD-Modified Adenovirus inOvarian CancerLena J. Gamble, Qiana L. Matthews, Anton V. Borovjagin, David T. Curiel.Cancer-Targeted Gene & Cell Therapy III843Increasing the Efficacy of Monoclonal Antibody Therapy of BreastCancer through Transient Remodeling of Intercellular JunctionsJonas Persson, Max Drescher, ZongYi Li, Roma Yumul, Ying Liu, Hongjie Wang, AkseliHemminki, Pascal Fender, Andre Lieber.844Improvement of Cancer Gene Therapy by Incorporating a ChickenHypersensitive Site-4 Insulator into TSTA-Based Tumor-TargetingVectorChien-Fu Chen, Yu-Ping Sher, Mien-Chie Hung, Chia-Ling Hsieh.Saturday, May 22 nd

138American Society of Gene & Cell TherapyAbstract DirectorySaturday, May 22 ndSaturday, May 22, 2010Poster Session III — continued6:00 PM - 8:00 PMRoom: Exhibit Hall CCancer-Targeted Gene & Cell Therapy III845Cytokine Induced Killer (CIK) Cells for Cell Therapy of AcuteMyeloid Leukemia (AML): Improvement of Their Immune Activity byExpression of CD33-Specific Chimeric Receptors (CR)Virna Marin, Irene Pizzitola, Valentina Agostoni, Helene Finney, Alastair Lawson, MartinPule, Raphael Rousseau, Andrea Biondi, Ettore Biagi.846Exosome-Mediated Suicide Gene Therapy for Brain TumorsArda Mizrak, Senol Ozlem, Baris G. Ozdener, Leonora Balaj, Johan Skog, Xandra O.Breakefield, Okay Saydam.847Eradication of Therapy-Resistant Human Prostate Tumors Using anUltrasound Guided Site-Specific Cancer Terminator Virus DeliveryApproachPier Paolo Claudio, Rounak Nande, Mary A. Teter, Paul B. Fisher, Sarkar Denavand, LuigiClaudio, Adelaide Greco, Candace Howard.848Systemic Tumour Targeting with Orally Administered Non-PathogenicBacteriaMichelle Cronin, David Morrissey, Simon Rajendran, Douwe van Sinderen, Gerald C.O’Sullivan, Mark Tangney.849Transient Intratumoral Relaxin Expression Results in Tumor StromaDegradation and Improves Breast Cancer Therapy by HerceptinZongYi Li, Ying Liu, Roma Yumul, Max Drescher, Jonas Persson, Ines Beyer, Andre Lieber.850Developing a Multi-Modal Gene-Based Imaging and Therapy To TreatDisseminated Hormone Refractory Prostate CancerZiyue Jiang, Makoto Sato, Lily Wu.851Adenoviruses-Mediated Expression and Cell-Mediated Delivery ofInterferon-Lambda Produced Anti-Tumor Effects to Human EsophagealCarcinoma In VivoMasatoshi Tagawa, Quanhai Li, Kiyoko Kawamura, Shinya Okamoto, Shan Yang, HiroshiKobayashi, Muneo Numasaki, Yuji Tada, Kenzo Hiroshima, Hideaki Shimada.852Inhibition of Angiogenesis and Suppression of Colorectal CancerMetastatic to the Liver Using the Sleeping Beauty Transposon SystemLalitha R. Belur, Kelly M. Podetz-Petersen, Brent Sorenson, Josh Parker, Cathy Carlson,Daniel Saltzman, Ramakrishnan Sundaram, R. Scott McIvor.853Plasmid AMEP, a New Efficient Antitumor Gene Transfer Product forthe Treatment of Metastatic MelanomasCeline Bouquet, Veronique Trochon-Joseph, Valerie Polard, Lluis M. Mir, MichelPerricaudet, Sophie Lebel-Binay.854Adenovirus-Delivered Short Hairpin-Structured RNA for MicrophageMigration Inhibitory Factor Silencing Inhibits Human Prostate CancerCell ProliferationLing Zhang, Anqi Wang, Chengyao Li, Hongwei Li, Leah N Braseth, Arseniy E Shabashvili,Colin Sumners.855Monitoring of Electroporation-Mediated Diphtheria Toxin AExpression in Prostate Cancer Cells Grown in SCID MiceChristine Goepfert, Felix J. Frey, Brigitte M. Frey.856Clinical Gene Transfer in the Community: Ten Years of Local IBCReviewJan P. Vleck.Hematologic and Immunologic Gene & Cell Therapy III857High Incidence of Vector Integration near Cancer-Related Geneswithin Primitive Hematopoietic Stem Cells (HSC) after Fetal GeneTransfer with g-Retroviral VectorsJoe Tellez, Josh Wood, Graça Almeida-Porada, Chris D. Porada.858Successful Treatment of Canine Leukocyte Adhesion Deficiency Usinga MSCV-Promoter Based Foamy Viral Vector and Low-Dose BusulfanConditioningThomas R. Bauer, Jr., Erik M. Olson, Laura M. Tuschong, James M. Allen, Tanya H.Burkholder, David W. Russell, Dennis D. Hickstein.859Genetically Engineered VIP-Expressing Dendritic Cells Are Therapeuticin the Autoimmune Mouse Model of Experimental AutoimmuneEncephalomyelitisMiguel G. Toscano, Mario Skarica, Weiming Kong, Doina Ganea.860Long-Term Preclinical Evaluation of Lentiviral Vectors for SCID-X1Gene Therapy in a SCID-X1 Mouse ModelSheng Zhou, Suk See DeRavin, Zhijun Ma, Taihe Lu, John T. Gray, Harry L. Malech, BrianP. Sorrentino.861Transduction of Human CD34+ Derived NOG Repopulating Cells withan Insulated SIN Lentiviral Vector for SCID-X1 Produced from aStable Producer Cell LineMichael R. Greene, Yoon-Sang Kim, Timothy Lockey, Paolo Fagone, Robert E. Throm,John T. Gray, Derek A. Persons, Brian P. Sorrentino.EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010139Abstract DirectorySaturday, May 22, 2010Poster Session III — continued6:00 PM - 8:00 PMRoom: Exhibit Hall CHematologic and Immunologic Gene & Cell Therapy III862Prevention of Atopic Dermatitis by Plasmid-Based SustainedTransgene Expression of Interferon g in NC/NGA MiceKayoko Hattori, Makiya Nishikawa, Kanitta Watcharanurak, Akihiko Ikoma, KenjiKabashima, Hiroyasu Toyota, Yuki Takahashi, Rei Takahashi, Yoshihiko Watanabe,Yoshinobu Takakura.863Expression of an Antibody Against CTLA4 from Tumor InfiltratingLeukocytes Induces Efficient Anti-Tumor Immune Responses in aMouse Model for Breast CancerJonas Persson, Ying Liu, Roma Yumul, ZongYi Li, Steve Roffler, Andre Lieber.864Foamy Virus Vectors with MGMT-P140K Mediate Efficient Selectionin a Canine Pyruvate Kinase Deficiency Model for HematopoieticStem Cell Gene TherapyBrian C. Beard, Robert A. Wu, Christina Ironside, Punam Malik, Kiem Hans-Peter,Trobridge D. Grant.865Modeling of Congenital Erythropoietic Porphyria by RNA-Interference: A New Tool for Preclinical Gene Therapy EvaluationHubert de Verneuil, Elodie Robert-Richard, Magalie Lalanne, Isabelle Lamrissi-Garcia,Véronique Guyonnet-Duperat, Emmanuel Richard, Frédéric Mazurier, Cécile Ged, FrançoisMoreau-Gaudry.866Gene Corrected Neutrophils from Induced Pluripotent Stem CellsDerived from an X-CGD Disease ModelSayandip Mukherjee, Giorgia Santilli, Michael P. Blundell, Elena Almarza, Juan Bueren,Adrian J. Thrasher.867The Comparison of Various Promoters for Wiskott Aldrich SyndromeGene Therapy Using Insulated Lentiviral VectorsRachel M. Koldej, Deepti Banka, Gael Carney, Hui Fen Zhao, Derek Persons, Arthur W.Nienhuis.868Sleeping Beauty-Mediated Therapeutic Gene Transfer intoHematopoietic Stem CellsKendra A. Hyland, Erik R. Olson, Xianzheng Zhou, R. Scott McIvor.869 (Moved to Poster Session I after Abstract 233)Myelospecific Self-Inactivating Gammaretroviral Vectors for p47 phoxCGD Gene TherapyVital Wohlgensinger, Christian Brendel, Axel Schambach, Manuel Grez, JanineReichenbach, Reinhard A. Seger, Ulrich Siler.870Delivery of Soluble ICAM-1 in NOD Salivary Glands Can Result in BCell Proliferation and Immunoglobulin ProductionJelle L. Vosters, Nienke Roescher, Paul P. Tak, John A. Chiorini.871Modulation of CXCR4 Expression by Novel Growth Factor Cocktail onStem CellsSomayeh Shahrokhi, Kamran Alimoghaddam, Massoumeh Ebtekar, Zohre Sharifi,Seyed Hamidolah Ghaffari, Ali Akbar Pourfathollah, Mahboobeh Mohseni, ArdeshirGhavamzadeh.Lung and Respiratory Disease Gene & Cell Therapy872Efficient Gene Delivery to Pig Airways Using Helper-DependentAdenoviral VectorsHuibi Cao, Jonathan C. Yeung, Cathleen Duan, Allan Coates, Kitty Leung, Shaf Keshavjee,Jim Hu.873SIV Vector Pseudotyped with SeV-F/HN Envelope Proteins ProducesLong Lasting Expression in the Murine Lung, Is Readministrable andTransfects Human Airway ModelsUta Griesenbach, Makoto Inoue, Cuixiang Meng, Andrea M. Brum, Raymond Farley,Nikki Newman, Eiji Akiba, Mamoru Hasegawa, Eric W. F. W. Alton.874Airway Lentiviral Gene Transfer In MarmosetsDavid Parsons, Richard Bright, Darren Miller, Don Anson.875Pulmonary Delivery of mRNA: In Vitro and In Vivo EvaluationOliwia Najder, Joanna Rejman, Stefaan De Smedt, Joseph Demeester, Mario VanPoucke, Luc Peelman, Niek N. Sanders.876Inhibiting Bap31 by Dominant Negative p20 Does Not Promote CFTRTranslocation to the Cell MembraneYadong Zhang, Wei Zhang, Min Li, T. C. Hwang, Yihong Ye, Dongsheng Duan.877Targeted siRNA Delivery to Lung Epithelia Reduces Mucus Secretionin a Mouse Model for Allergic AsthmaHyo Sung Choi, Jae Wook Jung, Hong Seok Ban, Nahyun Kim, Priti Kumar, Sang kyungLee.878The T1a Promoter Mediates Nuclear Import of Plasmid DNA intoAlveolar Epithelial Type I CellsLynn F. Gottfried, David A. Dean.Saturday, May 22 nd

140American Society of Gene & Cell TherapyAbstract DirectorySaturday, May 22 ndSaturday, May 22, 2010Poster Session III — continued6:00 PM - 8:00 PMRoom: Exhibit Hall CLung and Respiratory Disease Gene & Cell Therapy879Effects of LPC on Lung Mechanics in Non-Human PrimatesP. Hiatt, R. McConnell, N. Grove, D. Dang, N. Brunetti-Pierri, D. Palmer, A. Beaudet, P.Ng.880Repeat Aerosol Delivery of Concentrated PEI/pDNA to the SheepLungGerry McLachlan, Lee A. Davies, Cath M. Gordon, Christina Vrettou, Eilidh Baker, PeterTennant, Alison Baker, Rebecca L. Coles, Dominique McCormick, Stephanie G. Sumner-Jones, Stephen C. Hyde, Deborah R. Gill, D. David S. Collie.881Pseudotype Switching as a Strategy To Permit Efficient Re-Administration of Lentiviral Vectors to Mouse AirwaysJohn C. Olsen, Angela Giddings, Manij Patel.Oligonucleotide & RNAi Therapeutics III882Antinociceptive Potentiation and Attenuation of Tolerance byIntrathecal b-Arrestin 2 siRNA in RatsChung-Ren Lin, Kuan-Hung Chen, Chih-Hsien Wu, Yi-Sen Chen.883siRNA Cationic Delivery Systems for Therapeutic ApplicationsAnne-Laure D. Bolcato-Bellemin, Marie-Elise Bonnet, Gaëlle Deglane, Nathalie Lenne,Patrick Neuberg, Clément Paris, Jean-Paul Behr, Patrick Erbacher.884Therapeutic Effect of Intravenous Administration of New Type HybridStaple-Modified NFkB Decoy Oligonucleotides on InflammatoryBowel Disease Model MiceKazunari Ozaki, Hirofumi Makino, Takashi Miyake, Yasushi Takeya, Motokuni Aoki,Hiromi Rakugi, Ryuichi Morishita.885Artificial miRNA Clusters for Targeting Multiple Regions of the HCVGenomeXiao Yang, Virginia Haurigot, Shangzhen Zhou, Linda B. Couto.886Design and Pre-Clinical Evaluation of Adeno-Associated Viral (AAV)Vectors for Therapeutic Inhibition of Disease-Associated miRNAsNina Schürmann, Ellen Hoffmann, Dirk Grimm.887Safety Results of a Phase 1 Clinical Study for Treatment of Patientswith Advanced Solid Tumors with the TLR9 Agonist MGN1703Max E. Scheulen, Manuel Schmidt, Michael S. von Bergwelt-Baildon, Ulrich Hacker,Alexander Shimabukuro-Vornhagen, Heike Richly, Bahar Nokay, Marina Tschaika,Burghardt Wittig, Martin R. Weihrauch.888Parallel Assessment of Silencing Potency of Conventional SiRNAs vs.SiRNA VariantsNicholas M. Snead, Min-sun Song, Kumi Sakurai, John J. Rossi.889Inhibition of Viral Hepatitis with Non-Coding RNAsJovanna Gonzalez-Rojas, Amaya Abad, Lorea Blazquez, Nerea Razquin, Xabier Abad,Puri Fortes.890Screening of Nature Compounds for Enhancing AntisenseOligonucleotide-Induced Exon Skipping of Dystrophin Gene In Vitroand In VivoBo Wu, Caryn Cloer, Peijuan Lu, Mingxing Wang, Wei Li, Kazuo Koike, Qi Long Lu.891A Combination of PHD2 Prolyl Hydroxylase Silencing andBiocompatible Polyplex Nanocarrier Enhances TherapeuticAngiogenesisShourong Wu, Nobuhiro Nishiyama, Keiji Itaka, Takuya Hashimoto, Hiroyuki Koyama,Mitsunobu R Kano, Kazunori Kataoka.892Development of a Novel, RNAi-Based Therapeutic TargetingPancreatic Duodenal Homebox-1 (PDX-1) for Insulinoma andPancreatic CancerZhaohui Wang, Shi-he Liu, Donald D. Rao, Phillip B. Maples, Neil Senzer, JohnNemunaitis, F. C. Brunicardi.893Systemic Delivery of Highly Active Functionalized Lipopolyamine-Formulated siRNA to Murine Lung with Reduction of Inflammation byDexamethasone Pre-TreatmentJeff Sparks, Kevin J. Polach, Richard T. Congo, Gregory Slobodkin, Angela Rea-Ramsey,Casey Pence, Majed Matar, Diane McClure, Jennifer Rice, David Ulkoski, ElaineBrunhoeber, Leslie Wilkinson, Khursheed Anwer, Jason G. Fewell.894Ornithine and Tryptophan as an Efficient Polycation for siRNADelivery to Tumor CellsYusuke Sato, Hiroto Hatakeyama, Hideyoshi Harashima.895Influence of 5’ Terminal Triphosphate in Short Hairpin RNA TargetingHCV Replicon on Antiviral Activity and Innate Immune ResponseKyungbo Kim, Bokhui Lee, Soo-Ryoon Ryoo, Dal-Hee Min, Dong-Eun Kim.896Enhanced Delivery of GFP siRNA Using New Amino Lipid-BasedCationic LiposomesHyun-Ki Kim, Enkhzaya Davaa, Chang-seon Myung, Jeong-Sook Park.EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010141Abstract DirectorySaturday, May 22, 2010Poster Session III — continued6:00 PM - 8:00 PMRoom: Exhibit Hall COligonucleotide & RNAi Therapeutics III897Gene Editing Activity in C. elegans Directed by Single-StrandedOligonucleotidesKerry A. Falgowski, Eric B. Kmiec.Stem Cell Therapies898Engraftment into the Liver of Transplanted Adipose Tissue-DerivedStromal Cells Detected by Noninvasive Bioluminescence ImagingGiuliana Di Rocco, Antonietta Gentile, Annalisa Antonini, Maurizio C. Capogrossi, GabrieleToietta.899Establishment of iPS Cells Derived from the New World Monkey ofCommon MarmosetSaori Yamaguchi, Tomotoshi Marumoto, Hirotaka Kawano, Shinya Shimoda, YoshieMiura, Tomoko Inoue, Ryo Kurita, Hiroyuki Miyoshi, Erika Sasaki, Atsushi Takahashi,Kenzaburo Tani.900Umbilical Cord Blood-Derived Mesenchymal Stem Cells AcquireCardiac Phenotype with Oxytocin Treatment and Enhance CardiacRecovery after Myocardial InfarctionYong Sook Kim, Jin Sook Kwon, In-Kyu Park, Myung Ho Jeong, Youngkeun Ahn.901Ex Vivo Expansion and Enrichment of Murine Adult Neural Stem Cellsfor Gene Therapy of Neurogenetic DiseasesSushma Chaubey, John H. Wolfe.902Dual Effect of Mesenchymal Stem Cells Genetically Modified with aSingle-Chain Antibody Against EGFRvIII on the Targeting and Growthof EGFRvIII Expressing Experimental Glial TumorsIrina V. Balyasnikova, Sherise D. Ferguson, Yu Han, Maciej S. Lesniak.903Expression of Coagulation Factors from Murine iPS-Derived LiverCellsKohei Tatsumi, Yoshihiko Sakurai, Kazuo Ohashi, Shogo Kasuda, Junko Kato, TeruoOkano, Midori Shima.904The Granules Isolated from Mast Cells Have Increased the Survivalof Bone Marrow-Derived Mesenchymal Stem CellsJin Sook Kwon, Yong Sook Kim, In-Kyu Park, Myung Ho Jeong, Youngkeun Ahn.905Large-Scale Expansion of Undifferentiated Human Embryonic StemCells in Serum-Free Suspension CultureVincent C. Chen, Sylvana Couture, Jonathan Auerbach, Araz Toumadje, Lara Ausubel,David Hsu, Larry Couture.906Enrichment of Bone Marrow Stem Cells In Vivo by Dissociation- andProliferation-Inducing Compounds Augments Bone Growth in aMouse Segmental Bone Defect ModelSanjay Kumar, Selvarangan Ponnazhagan.907A Delayed Treatment of Mesenchymal Stem Cells Is Effective inRescuing Mice with Established LPS-Induced Acute Lung InjuryShirley H. J. Mei, Colleen H. Parker, Conrad Liles, Duncan J. Stewart.908Lentiviral Vector-Mediated Transduction in Murine SMA EmbryonicStem Cells Derived from Spinal Muscular Atrophy (SMAI) MiceArianna Malgieri, Andrea Luchetti, Massimo Sanchez, Maria Bellocchi, Paola Spitalieri,Douglas A. Kerr, Giuseppe Novelli, Federica Sangiuolo.909Development of a Reporter System for I-SceI-Mediated GenomeEditing in Canine Hematopoietic Stem CellsNina M. Muñoz, Grant D. Trobridge, Brian C. Beard, Byoung Y. Ryu, Andrew M.Scharenberg, Hans-Peter Kiem.910Liver Disease Correction with Cells Isolated from Cadaveric LiverLaura Erker, Hisaya Azuma, Laura Eaton, Eric Benedetti, Bryan Jensen, Andrew Y. Lee,Milton Finegold, Holger Willenbring, Markus Grompe.911Efficient Gene Transfer into CD34+ Hematopoietic Stem Cells UsingClinical Grade Lentiviral Vector Expressing the Human Beta-GlobinGeneClare Taylor, Leda Ferro, Jason Plotkin, Xiuyan Wang, Michel Sadelain, Isabelle Rivière1.912Embryonic Stem Cell Therapy Enhances Tendon Regeneration in aLarge Animal Flexor Tendonitis ModelAlan J. Nixon, Ashlee A. Watts, Oleg Kopyov.913Generation of Cystic Fibrosis Induced Pluripotent Stem (iPS) Cells forGene TherapyR. G. Sargent, Y. Yang, A. Lee, S. Kim, L. Ye, J. Chang, D. C. Gruenert.Saturday, May 22 nd

142American Society of Gene & Cell TherapyAbstract DirectorySaturday, May 22 ndSaturday, May 22, 2010Poster Session III — continued6:00 PM - 8:00 PMRoom: Exhibit Hall CLate Breaking Science III938Blockage of Viral RNA Transport of REV- and CTE-DependentLentiviral Vectors Encoding NUP98 Fusion GenesYildirim Dogan, David C Dorn, Sutapa Sahay, Anna Franceschino, Malcolm AS Moore.939Novel Helper-Independent piggyBac Plasmids for Gene DeliveryApproachesJohann Urschitz, Chad Walton, Jesse Owens, Miyuri Kawasumi, Hideaki Yamashiro, IlkoStoytchev, Joel Marh, Craig J. Coates, Joseph M. Kaminski, Pawel Pelczar, Ralph V.Shohet, Stefan Moisyadi940Transgene Trafficking to Nuclear Periphery is a Barrier to Transfectionin a Lipid Substituted Nonviral Cationic PolymerCharlie Y-M Hsu, Hasan Uludag.941Studies on the Biodistribution Evaluation of Gene Therapy Productsusing the Real Time-PCRSong Hyun, Choi Min Joung, Seo Su Jin, Han Sung Yeol, Lee Yeon Ho, Park Youn Joo,Ahn Kwang Soo, Kim Tae Geun.942Activity, Integration Preferences, and Localization of TcBuster; aNovel hAT Transposon SystemLauren E. Woodard, Aparna Kaja, Robert H. Hice, Peter W. Atkinson, Nancy L. Craig,Matthew H. Wilson.943Overcoming the Lipofection Resistance of Oral Cancer Cells:Polyplexes and AdenovirusesSenait Gebremedhin, Krystyna Konopka, Ilya Ulasov, Maciej Lesniak, Nejat Düzgünes.944Association of CD44 Expression with Hormone Receptor Status inBreast CancerP Olivera, E Ortiz, R Romero, A Palacios, R Morales, G Cervantes, S Galván, E Langley,A García-Carrancá.945Systemic Apoptotic Gene Therapy for Pancreatic Cancer: Multi-DoseToxicity Study of the BikDD NanoparticleK Barnhart, M Javle, S Miller, J Hsu, J McMannis, P Smith, J Abbruzzese, MC Hung.946Phosphatidylserine Immobilization of Lentivirus for Localized GeneTransferSeungjin Shin, Hannah M. Tuinstra, David M. Salvay, Lonnie D. Shea.947Engineering Adenovirus Serotype 5 Vectors to Increase HepatocyteTransduction for Liver Gene TherapyReeti Khare, Michael A. BarryEXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 143Abstract Author IndexAAagaard, Lars. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 695Aalbers, Caroline J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 66Aartsma-Rus, Annemieke . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 153Abad, Amaya . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 889Abad, Xabier . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 889Abay, K. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 777Abbasi, Meysam. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 562, 568Abdelbary, Hesham . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 39Abdulrasul, Fouzia. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 349Abrameto, Javier A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 616Abu-Asab, Mones . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 135Acharya, Bishnu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 216Adachi, Kei . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7, 703Adair, Jennifer E.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 294Adamo, Richard . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 323Adamo, Richard F.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 425Adams, Marvin E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 584Adams, Samuel J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 622Adriaansen, Janik . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 761Affin, Lulit A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 125Aflaki, Pejman . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 237Agbandje-McKenna, Mavis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 65Agerholm-Larsen, Birgit . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 109Agkatsev, Sarina. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 602Agostoni, Valentina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 845Agudo, Judith. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 140, 762Ahlén, Gustaf . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 111Ahlen, Gustaf . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 289Ahlzadeh, Garbielle . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 475Ahmad, Farizan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 212, 512Ahmad, Sarfraz . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 812Ahmed, Atique U. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 191, 718, 835Ahmed, Nabil . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 179, 470, 471Ahmed, Sherif O. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 451Ahn, Miwon . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 52Ahn, Youngkeun . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 399, 751, 900, 904Ahouansou, Ornella. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19Ahrens, Eric . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 271Ahtiainen, Laura . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 197, 291Aimi, Junko . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 35Airavaara, Mikko T. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 709Airenne, Kari J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 669Aiuti, Alessandro. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 225, 229, 276,. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 295, 345Akbulut, Hakan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 85Akiba, Eiji . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 873Akita, Hidetaka . . . . . . . . . . . . . . . . . . . . . . . . . . . . 246, 253, 401, 591, 743Akkina, Ramesh . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 287Alba, Raul . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 380, 573Albelda, Stephen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 611Alberici, Luca . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 644Albrecht, Douglas E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 796Al-Dahhak, Roula . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 155Alden, Anderson . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 181Aldhamen, Yasser A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 638, 651Aldrich, Carla J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 332Alemany, Ramon . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 291, 496Alexander, Ian E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 409Alfaro, Carlos . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 42Alferiev, Ivan S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 425Ali, Nowrouzi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 138Alimoghaddam, Kamran. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 871Allain, Jean-Pierre . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 808Allay, James A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 668Allen, Cornell . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 675Allen, Cory. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 490, 499Allen, Henry. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 536, 586Allen, James M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 234, 459, 786, 858Allen, Lee . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 576Allen, Michael H. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 122, 125Allen, Phil . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 392Allimperti, Stella . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 358Allocca, Mariacarmela . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 64Almarza, David. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 351Almarza, Elena. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 866Almeida-Porada, Graça. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 551, 857Alton, Eric W. F. W. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 873Alvarez, Ronald D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 36, 503, 507, 834Alves, Paula M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 278, 570, 579Alzadeh, Gabrielle. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 181Alzuguren, Pilar . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 810Amalfitano, Andrea . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 638, 651Amaral, Ana I. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 278Amarnath, Shoba . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 341Ambrosi, Alessandro . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 345, 346Amendola, Mario . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 413An, Weijun. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 603Anagnostopoulos, Achilles . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 137Anagnou, Nicholas P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 338Anderson, Jonathan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 277, 279Anderson, Joseph . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 281Anderson, Susan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 300Ando, Dale. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 783, 798Andre, Kris. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 41, 803Andreadis, Stelios . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 359Andreadis, Stelios T. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 358, 282Andreani, Marco . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 319

144American Society of Gene & Cell TherapyAbstract Author IndexAndresen, Thomas L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 511Angell, Yu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 731Anguela, Xavier M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 140Anikster, Yair . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 144Annan, Anand C.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 503Annoni, Andrea. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 545Annunziata, Patrizia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 758Anson, Don . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 874Anson, Donald . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 621Ansorge, Sven . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 361Antonini, Annalisa . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 898Antoniou, Michael N.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 531Anwer, Khursheed . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 893Aoki, Motokuni. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 884Aoki, Yoshitsugu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 565Appledorn, Daniel M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 638, 651Aramaki, Yukihiko. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 102Aras, Rahul A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 426, 438Arbuthnot, Patrick . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 82, 563Ardiani, Andressa . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 330Arens, Anne . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 286, 305, 347Ariga, Tadashi. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 678Arkin, Adam P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 802, 805Arman, A. Cyrus . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 21Armaroli, Annarita. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 258Armstrong, Adam . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 633Arnett, Andrea L.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 461Arning, E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 139Arntz, Onno J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 559, 627Aronovich, Elena L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 325, 728Aronow, Bruce J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 830Arruda, Valder R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 308, 551, 614, 615Arsenau, James . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 35Arshad, Shazia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 530Arstila, Petteri. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 538Arun, Srivastava . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 68Arzberger, Silke . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 312Asakawa, Nagisa . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 410Asdourian, George. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 444Asefa, Benyam. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 165Aslanidi, George . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 363, 370, 378Asokan, Aravind . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 62, 160, 364, 367, 403Assi, Hikmat . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 26, 181Astone, Dalila. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 435Astrakhan, Alexander. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 343, 529Athanassiadou, Aglaia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 340, 729Atkins, Harry . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 39Aubert, Dominique . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 138Aubourg, Patrick . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19Audet, Sarah . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 402Auerbach, Jonathan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 905Aurelian, Laure . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 717Auricchio, Alberto . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 59, 64, 443, 624, 758Aurigemma, Rosemarie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 36Ausubel, Lara . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 905Ausubel, Lara J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 277, 279Aviles, Misael O.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 121Ayuso, Eduard . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 762Azuma, Hideki . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 397Azuma, Hisaya. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 910bBacci, Maria Laura . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 59Back, Jin Ee. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 128Badding, Melissa A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 588Baek, Jin Ee. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 406, 754Bagarazzi, Mark. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 477Bahar, Bahar . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 664Bahou, Wadie F. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 372Bailey, Debra . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 739Bais, Anthony J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 27Bajzer, Zeljko. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 208Bak, Rasmus O. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 695, 726Bakay, Marina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 425Baker, Alison . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 880Baker, Andrew H. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 380, 715, 723Baker, Andrew J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 783Baker, Eilidh. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 880Baker, K. Scott . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 232Balaj, Leonora . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 846Baldim, Victor . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 485Balducci, Anthony G. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 271Bali, Deeksha. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 136Bali, Pawan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 678Ball, Claudia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 612Ballmaier, Matthias . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 318Balyasnikova, Irina V. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 902Balyasnikova, Irina Y. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 191Balzer, Frederick. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 156, 454Ban, Hiroshi. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 303, 634Ban, Hong Seok . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 877Ban, Hong-Seok . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 407Bandyopadhyay, Sarmistha . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 711Banfi, Andrea . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 430, 597Banka, Deepti . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 867Banks, Glen B. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 459, 584Banwell, Brenda . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 155Baranov, Vladimir . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 57EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 145Abstract Author IndexBaranov, Vladislav S.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 750Baranyi, Lajos . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 527Barbas, III, Carlos . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 340Barbas, III, Carlos F. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 94, 339Barber, Glen. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 604Bareja, Akshay . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 466Barlow, Robert . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17Barnes, Justin A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 503Barohn, Richard J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 155Baron, Stéphanie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 226Barouch, Dan H. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 723Barron, Valerie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 439Barry, Frank. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 270Barry, Michael A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 81Bartek, Jiri. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 265Bartholomae, Cynthia C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 297,. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 298, 345, 346, 347Bartido, Shirley . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 32Bartlett, Jeffrey S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 547, 699Bartoli, Marc . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 48Barve, Minal . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 292, 335Barzel, Adi. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16Basner-Tschakarjan, Etiena . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 43Bassi, Elena . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 666Basu, Gaurav . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 107Batchu, Ramesh B. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 250Batchvarova, Milena . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 667Batshaw, Mark L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 416Batsis, Ioannis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 137Bauer, Gerhard . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 281Bauer, Jr., Thomas R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 234, 858Bauerschmitz, Gerd. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 193Baum, Bruce J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 74, 77, 143, 761Baum, Christopher . . . . . . . . . . . . . . . . . . . . . . 284, 302, 304, 318, 528, 619Baumhover, Nicholas J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 117, 594Bazzani, Reto P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 739Beal, Nikia L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 445Bear, Adham . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 469Bear, Adham S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 816Beard, Brian C.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 294, 864, 909Beaudet, A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 879Beaudet, Arthur . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 639Beaudoin, Esther L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 27Becher, Ulrich M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 693Bechinger, Burkhard . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 400Becker, Pamela . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 137, 294Bedell, Cynthia. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 292, 335, 536Beheshti, Ben. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 217Behr, Jean-Paul. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 883Behr, Michael. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 381Belicchi, Marzia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 460, 464, 795Bell, Christie L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 65Bell, Jason B.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 325, 728, 734Bell, John C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 33, 37, 39Bell, Peter L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 45, 412, 416, 543, 759Bellavia, Diego . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 599Bellayr, Ian . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 465Bello, Alexander J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 64Bellocchi, Maria . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 908Beloglazova, Irina. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 434Belousova, Natalya . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 725Belur, Lalitha R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20, 852Benati, Claudia. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 276Benderdour, Mohamed . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 756Bendjelloul, Mehdi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 463Benedetti, Eric . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 910Benedetti, Lorena . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 834Benedicenti, Fabrizio. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 297, 298Benes, Vladimir . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 270Bengtson, Karen. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 803Benito, Alberto . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 42Bennett, C. F.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 55Bennett, C. Frank . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 557Bennink, Miranda B. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 559, 627Benvegnu, Thierry. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 120Benza, Raymond L.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 104Berger, Carolina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 618Bergmann, Juri. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 237Bernard, Robert . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 162Berraondo, Pedro . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 485, 810Berry, Charles C.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13Bertin, Terry K. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 642Bertolotti, Roger . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 244Bertrand, Emilie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 395Besarab, Anatole . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 616Besharse, Joseph C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17Betts, Michael R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 164Beuerlein, Michele . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 280Beyer, Ines . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 264, 849Bhasvar, Janak. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 269Bhatnagar, Rakesh . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 562Bhavsar, Janak. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 272Biagi, Ettore. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 845Bian, Ang . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 389Bian, Yixin. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 806, 808Bianco, Paolo. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 133Biasco, Luca. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 225, 345Bienemann, Alison . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 394

146American Society of Gene & Cell TherapyAbstract Author IndexBien-Willner, Ricardo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 155Biffi, Alessandra . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 276, 313, 315, 316Bigey, Pascal . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 791Bikram, Malavosklish . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 405Billiet, Ludivine. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 395Binder-Scholl, Gwendolyn. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 798Bindra, Ranjit S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 50, 285Biondi, Andrea . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 845Bird, Andrew . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 142Bisgrove, Dwayne. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 674Bish, Lawrence. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 433, 625Bisordi, Katie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 630Biswas, A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 223, 697Bizario, João C. S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 790Black, Margaret E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 330Blake, Bonita . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 355Blake, Bonita L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2Blanchard, Jan E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 39Blanco, Laura. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 485, 708Blasczyk, Rainer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 612Blau, Carl A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 730Blazar, Bruce R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 221Blazquez, Lorea . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 889Blechingberg, Jenny . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 91Blick, Gary. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 646Blits, Bas. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 249Blondeau, Johanna . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 229Blundell, Michael P.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 866Blundell, Mike . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 229Boccalatte, Francesco . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 337Bochner, Bernard H. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 334Boczkowski, David . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 561Bodine, David M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 521Bogan, Janet . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 454, 458, 467, 785Böhm, Marie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 612Boisgérault, Florence. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 48Bolcato-Bellemin,Anne-Laure D.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 883Bollard, C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 30Bollard, Catherine . . . . . . . . . . . . . . . . . . . . . . . . . . . 29, 288, 293, 471, 473Bolund, Lars. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 91Bolyard, Chelsea M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 547Bomsztyk, Karol . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 93Bondanza, Attilio . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 295, 654Bonetti, Ciro. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 624Bonfiglio, Serena . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 795Bonini, Chiara . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 88, 295, 346, 632, 654Bonner, Melissa A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 569Bonnet, Marie-Elise . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 883Bonten, Eric . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 449Bookay, Haddas . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 616Bordignon, Claudio . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 276, 295, 654Borenstein, Ronen. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 719Borisenko, Grigory G. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 735Borovjagin, Anton V. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 842Borquez-Ojeda, Oriana. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 32, 184Bortolanza, Sergia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 494Bosch, Assumpció . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 573Bosch, Fàtima . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 140Bosch, Fatima . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 762Bosma, Piter J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 138Boss, Hannah. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 27Bossow, Sascha . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 833Bosticardo, Marita. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 225Bostick, Brian P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 601Botchkina, Galina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 266Bottiglieri, T. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 139Bottinelli, Roberto. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 795Boulet, Sabrina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 777Boulis, Nicholas M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 699, 778, 782Bouquet, Celine . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19, 110, 113, 853Bourdel, Alix . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 87Bourke, Michael G. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 736Boutin, Sylvie. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 67Bovolenta, Chiara . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 644Bovolenta, Matteo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 258Bowers, William J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 18, 23, 76Bowles, Dawn . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 581Bowles, Dawn E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 366Boyd, Surina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 164Boyden, Edward S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 21Boye, Sanford L.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17, 71Boye, Shannon. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 71Boye, Shannon E.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17, 21Boyer, Jean . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 477Boyle, Kristy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 267, 461Boztug, Kaan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 612Bradley, Allan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15Bradshaw, Angela . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 723Bradshaw, Angela C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 380, 715Brady, James . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 675Brady, Troy L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13Brambilla, Riccardo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 315Bramson, Jonathan L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 79Braseth, Leah N.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 518Braseth, Leah N . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 854Bratasz, Anna. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 836Braun, Stephen E.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 645EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 147Abstract Author IndexBravo, Alicia J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 834Brayman, Andrew A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 326Breakefield, Xandra O. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 57, 665, 846Bredius, Robbert. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 225Breitbach, Caroline . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 33Bremer, William . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 149Bremer, William G. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 290Brendan, Lee H. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 642Brendel, Christian . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 869Brenner, Malcolm K. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 28, 29, 30,. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 178, 288, 293, 672, 799Brennig, Sebastian . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 528Brentjens, Renier J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 32, 183, 815Breous, Ekaterina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 543Bresolin, Nereo. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 464, 795Breuzard, Gilles . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 395Bridges, Charles . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 156, 454Bridges, Charles R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 600Bright, Richard . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 874Brigida, Immacolata . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 295, 345Brioschi, Simona. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 258Brittebo, Eva . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 453Broccoli, Vania . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 632Broderick, Jennifer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 362Broderick, Kate E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 103, 115, 327Brown, Brian . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 613Brown, Eric . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 391Brown, Eric D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 39Brown, Eric J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 497Brown, Ryan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 39Brown, Talmage T. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 142Browne, Andrew W. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 201Broxtermann, Mathias. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 312Brugiere, Pierre . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 777Brugman, Martijn . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 284Brugman, Martijn H. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 619Brum, Andrea M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 873Brumbach, Jonathan H. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 126Brunetti-Pierri, N. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 879Brunetti-Pierri, Nicola. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 75, 388, 639, 677Brunhoeber, Elaine . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 893Brunicardi, F. C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 247, 564, 731, 892Bryan, Nathan S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 677Bryant, Christopher S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 250Bu, Jie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 55Buchlis, George . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 546Buening, Hildegard . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 312Bueren, Juan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 866Büning, Hildegard . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5Bunnell, Bruce . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 314Bunnell, Bruce A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 411Buñuales, Maria . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 494Burel Deschamps, Laure. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 745Burgess, Kevin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 731Burke, James. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 33Burke, James M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 35Burke, Kathleen C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11Burkholder, Tanya H.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 234, 524, 858Burnett, John C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 599, 805Burnette, Angela D.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 667Burnnet, Erin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 767Burris, Clark A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 76Bushman, Frederic D. . . . . . . . . . . . . . . . . . . . . . . . . . 13, 228, 283, 308, 346Bussadori, Giulio. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 308Busuttil, Ronald W. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 44, 224, 373Butler, Greg . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 488Butler-Browne, Gillian . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 789Byrne, Barry J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 290, 371, 378, 596Byrnes, Andrew P.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 542CCaccavelli, Laure. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 229Cafferata, Eduardo G. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 609Cai, Hancheng . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 200Cai, Shangde . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 185Cai, Ying . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 739Calabrese, Christopher . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 449Calcedo, Roberto . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 45, 164Callejas, David . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 140Campbell, Jarryd M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 599Campbell, Katherine . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 149, 581Campbell, Katherine J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 155, 290Campeau, Philippe M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 677Campion, C. A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 194Cancelas, Jose A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 526Candolfi, Marianela. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 26, 181, 475Candotti, Daniel . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 808Candotti, Fabio. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 227, 296, 678Cannon, Paula M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11Cantore, Alessio . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 297, 545, 613Cantz, Tobias . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 284, 528Cao, Huibi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 872Cao, Maohua . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 429, 436, 437, 711Cao, Ou. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 146, 763Capalbo, Anita . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 758Capogrossi, Maurizio C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 898Cappelli, Barbara . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 225Carbonaro, Denise A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 296, 414

148American Society of Gene & Cell TherapyAbstract Author IndexCardoso, Rosana. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 349Carillo-Carrasco, Nuria . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 679Carlson, Cathy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 852Carmoy, Nathalie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 120, 131, 745Carnathan, Diane G. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 164Carnes, Aaron E.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 572, 575Carney, Gael . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 867Carpenter, Kevin H. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 409Carr, Bob. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 577Carragher, Bridget. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 393Carrer, Alessandro . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 431Carroll, Richard. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 798Carrondo, Manuel J. T.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 278, 579Carrum, George . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 288, 293Cartier, Nathalie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19Carvalho, Leonardo P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 440Carville, Angela . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 645Casellas, Alba. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 140, 762Casey, Garrett . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 812Cashman, Siobhan M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 447, 448Casimir, Colin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 349Casorati, Giulia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 654Cassani, Barbara. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 617Castiello, Maria C.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 225Castro, Maria G. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 26, 181, 475Cataldi, Marcela P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 307Cataliotti, Alessandro. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 599Cathomen, Toni . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16, 95Cattaneo, Roberto. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 168, 833Cattoglio, Claudia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 346, 523Cavazzana-Calvo, Marina. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13, 229, 617Cawley, Niamh X. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 143Cela, Racel . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 46Cela, Racel G. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 224, 642Cerri, Federica . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 315Cersosimo, Stefania . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 133Certo, Michael T.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 90Cerullo, Vincenzo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 177, 193, 197,. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 204, 291, 538, 549, 642, 658Cervio, E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 360Cesana, Daniela . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 297, 298, 632Cesaro, P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 777Chéradame, Hervé . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 395Cha, Yeon-Sook . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 818Chae, Jin-A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 818Chamala, Sreedhar . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 250Chamberlain, Jeffery . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 553Chamberlain, Jeffrey S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 267, 459,. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 461, 466, 468, 584, 786, 792Chamberlain, Marc . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 294Champlin, Richard E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 479Chan, Emma . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 647Chan, J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 223, 697Chan, Janet . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 640Chan, Jerry . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 531Chand, Allan R.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 64Chanda, Diptiman . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 63Chandler, Randy J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 135, 679, 701Chandra, Pallavi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 127Chandra, Ravi K.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 262Chandrasekaran, Suma . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 679Chandrashekran, Anil. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 349Chang, Chung-Che. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 293Chang, Esther. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 536Chang, J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 913Chang, Yu-Han . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 583Channon, Keith M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 602Chaouch, Soraya . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 789Chapdelaine, Pierre . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 462, 790Charan, Rakshita . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 455Charrier, Sabine . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 229Chase, Lucas . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 268Chatterjee, Anindo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 127Chatterjee, Saswati. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3Chaubey, Sushma . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 901Chekmasova, Alena A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 183Chen, Baihong . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 219Chen, Chien-Fu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 844Chen, Christopher Y. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 81Chen, Dong . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 605Chen, Fang . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 130Chen, Haifeng . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 72Chen, Heng . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 389Chen, Hong . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 172Chen, Jesse . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 467Chen, Jessie. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 156Chen, Jianzhu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 531Chen, Kuan-Hung . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 882Chen, Li. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 574Chen, Liping. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 326Chen, Margaret . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 289Chen, Shu-Jen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 625Chen, Thomas C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 200Chen, Vincent C.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 905Chen, Xizhe . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 427Chen, Y.-T. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 136Chen, Yifeng . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 548Chen, Yi-Sen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 882EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 149Abstract Author IndexChen, Zhi-Ying . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9, 14Chen, Ziping C.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 422, 800Chen, Zixuan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 171, 806, 807Chenajovsky, Yuti . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 609Cheng, Binbin. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 700Cheng, Kun . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 567Cheng, Linzhao . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 220Cheng, Long . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 130Cheng, Seng H. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 55, 557Cheng, Woei Ping . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 254Cherel, Yan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19Cherqui, Stephanie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 408Chester, John . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 606Cheung, Roland . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 367Chicoine, Louis G. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 149Childers, Martin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 454, 458, 467, 785Chillón, Miguel . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 573Chinnasamy, Nachimuthu. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 190Chino, Takenao. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 628Chiocca, E. A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 491Chiocca, E. Antonio . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 498Chiocco, Matthew J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 709Chiorini, John A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 483, 870Cho, Hanna . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 560Choi, Connie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 156Choi, Hye Jin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 198Choi, Hyo Sung . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 877Choi, Il-Kyu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 198, 202, 242, 516Choi, Joung-Woo. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 383, 721Choi, Keum S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 722Choi, Kyoung-ju . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 188Choi, Kyung-Ju . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 202, 811Choi, Min Joung . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 112Choi, Uimook. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 220, 354Choi, Vivian M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 98Choi, Yejin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 722Choi, Yeong “Christopher” . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 296Chong, Heung . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 606Chong, Mark . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 531Choolani, M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 223, 697Choolani, Mahesh. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 531Chopra, Manisha . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 328Chorny, Michael . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 323, 425Chou, Bin-Kuan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 220Chow, Laura. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 33Chowdhury, Wasim . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 382Chowdhury, Wasim H. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 390Christensen, Camilla L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 206, 210, 511Christensen, Rikke . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 91Christiansson, Lisa H.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 486, 820Christin, Anne S.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 29Christopher, Logg R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 492Chu, Baocheng. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 553Chu, Kirk . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 310Chulay, Jeffrey D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 377Chun, Kyung-Hee . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 384Chung, Samuel. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 405Chuvilin, Andrey N. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 735Ciccone, Carla . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 144Ciceri, Fabio. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 295Ciré, Séverine. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 552Ciuffreda, C.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 360Clark, K. Reed . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 149, 290, 581Clarke, Christian . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 642Claudio, Luigi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 847Claudio, Pier Paolo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 847Clay, Timothy C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 47Clemens, Paula R.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 455, 457, 580Clevenger, Joshua R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 96Cline, Amanda . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 521Cloer, Caryn . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 890Cloutier, Denise A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 596Cmielewski, Patricia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 621Coady, Tristan H.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 626Coates, Allan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 872Cockrell, Adam S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 355, 534Cody, James J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 507Coffey, Matt. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 606Cohen, Justus B.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 640Cohen, Reuben. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 274Colella, Pasqualina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 443Coleman, John S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 668Coles, Rebecca L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 880Coley, Brian . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 581Coley, Brian D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 149, 290Collantes, María . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 42Colle, Marie-Anne . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19Collie, D. David S.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 880Collins, J. K.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 194Collins, Margaret H. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 498Collins, Michael T.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 761Collins, Sara A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 705Compte-Grau, Marta . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 481Condomines, Maud . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 655Congo, Richard T. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 893Conlon, Thomas . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 290Connolly, Mary M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 727Constantinou, Varnavas . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 137

150American Society of Gene & Cell TherapyAbstract Author IndexConti, Peter S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 200Convertine, Anthony C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 558Cooper, Laurence J. N.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 479, 809Cooper, Mark J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 445, 622, 776Cornetta, Kenneth G.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 353, 356, 675Coroadinha, Ana S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 278, 570Cosset, Francois-Loic . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 336Costa, Caroline . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 336Cotrim, Ana P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 74, 77, 143Cots, Dan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 573Cotugno, Gabriella . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 758Coughlan, Lynda. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 380, 723Couto, Linda . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 69Couto, Linda B.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 885Couture, Larry . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 277, 279, 905Couture, Sylvana . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 905Cowan, Morton J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 221Cox, Josephine. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 162Cox, Julie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 39Craig, Anthony T. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 70Craig, Nancy L.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15Cramer, Frederik. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 206, 210, 511Crasta, Manuela . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 59Creencia, Christopher. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 794Crettaz, Julien . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 810Cripe, Timothy P.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 201, 498, 830Criswell, Hugh E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2Crombleholme, Timothy M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 830Crome, Sarah Q.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 79Cromley, Debra. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 412Cronin, Michelle . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 398, 812, 848Crowley, Jim . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 439Crowther, Carol. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 82Croyle, Maria . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 435Cruz, Conrad R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 473Cruz, Pedro E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 579Cruz, Russell . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 288Cruz, Russell C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 29Crystal, Ronald G.. . . . . . . . . . . . . . . . . . . . . . . . . . . . 19, 161, 163, 452, 752Cunningham, Sharon C.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 409Cunningham, Tshaka . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 70Curiel, David T. . . . . . . . . . . . . . . . . . . . . . . . . . . 36, 379, 497, 503, 834, 842Curran, Kevin J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 815Currier, Mark A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 201, 498Curtin, James F. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 181Custers, Jerome . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 723Cutler-Strom, Richelle . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 558Cutrera, Jeffry J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 737Dda Silva Bizario, Joao . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 464Dae, Hyun Mi. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 386D’Agostino, Karla . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 50Dai, Jihong . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 310Dai, Kerong . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 756Dalkara, Deniz . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 442Dally, Len . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 162Dam, Elisabeth. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 110Dam, Tomas N. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 695Dane, Allison P.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 409Daneshmand, Manijeh. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 33Dang, D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 879Danièle, Nathalie F.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 793Daniel, Skuk . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 769Danieli, P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 360Danos, Olivier. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 87, 617D’Antona, Giuseppe. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 795Dantzer, Jessica . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 353, 356Dar, Gulam H. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 404Darocha, Sylvie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 48Darvish, Daniel. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 144, 772, 794Darvish, Sheila . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 794Dasgupta, Anindya . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 814Dasouki, Majed . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 155Dassie, Justin P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 662, 663Davaa, Enkhzaya . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 896David, A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 223Davidoff, A. M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 223Davidoff, Andrew . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 668Davidson, Jesse T.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 452Davies, Kay E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 466Davies, Lee A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 123, 727, 880Davila, J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 139Davis, Adam S.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 699Davis, Nancy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 149Davis, Pamela B. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 746Davydova, Julia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 80, 391, 497d’Azzo, Alessandra . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 449D’Costa, Jenice. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 422De, Bishnu P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 161, 452, 752De Angelis, B. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 178de Boer, Helen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 617de Cortie, Karin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 231De Falco, Elena . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 229De Groot, Anne S.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 43De Kruijf, Marcel. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 736De Leonibus, Elvira . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 758De Palma, Michele . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 331EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 151Abstract Author IndexDe Ridder, Corrina M. A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 506de Silva, Suresh . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 76De Smedt, Stefaan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 875De Smedt, Stefaan C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 742de Verneuil, Hubert . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 865de Winter, Christa L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 153Dean, David A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 588, 878Deglane, Gaëlle . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 883Deisseroth, Albert . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 85Del Campo, Jacob. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 285del Campo, Jake. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 50Del Carro, Ubaldo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 313, 315Delépine, Pascal . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 745Delai, Stefania . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 315Delalande, Anthony. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 324Delisle, Josie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 649Della Corte, Michele . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 59Demaster, Amanda K. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 142Demeester, Jo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 742Demeester, Joseph . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 261, 875Denapoli, Priscila M. A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 440Denaro, Maria . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 228Denavand, Sarkar . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 847Denby, Laura . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 723Deng, Defeng. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 731Deng, Yao . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 78, 172Denisenko, Oleg . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 93Denman, Cecele J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 479Denning, Gabriela . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 527Denovan-Wright, Eileen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 147Dent, Paul . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 503DeRavin, Suk See. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 354, 860Derecho, Ivy. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 277, 279Derendorf, Hartmut. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 256DeRossi, Charles . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 348, 650Desai, Maya K.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 18Desmedt, Stefaan S. D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 261Dev, Jyoti . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 208Devine, Sean P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 509, 771DeWeese, Theodore L.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 251Dhar, Debanjan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 489, 837Di, Wei . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 158Di Domenico, Carmela . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 315Di Girolamo, Ilaria. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 316, 413Di Natale, Paola . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 315Di Paolo, Nelson C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 541Di Pasquale, Giovanni . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 483Di Rocco, Giuliana. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 898Di Scala, Marianna . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 485Di Serio, Clelia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 345, 346Di Stasi, Antonio. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 288Di Stefano, Bruno . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 632Di Vicino, Umberto . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 59, 443, 624Diaconu, Iulia. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 193, 204, 538, 549Diago, Oscar . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 492Diallo, Jean-Simon . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 39Dias, João D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 204Diaz, Deanna . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 477Diaz, Rosa. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 175, 481, 606, 607, 610Dibb, Nick . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 349Dibra, Denada . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 737Dieci, Marco. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 276Diepolder, Helmut M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 289Dietz, Allan B. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 488Dighe, N.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 223Dighe, Niraja . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 531Dinauer, Mary . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 356Dinauer, Mary C.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 353, 354Dinculescu, Astra. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 61Dindot, Scott . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 75Dines, Karla A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 445, 622Dingli, David . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 208, 684Diouf, Oumar . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 288DiPasquale, Betsy A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 498Discher, Dennis E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 357Dixon, Tracy. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 157, 514, 515Dmitrieva, Nina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 199Doering, Christopher B. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 230, 527Doglioni, Claudio. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 297Doherty, Joseph E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15Dohmann, Hans F. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 440Dolphin, Colin T. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 716Dolter, Karen E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 162, 740Doms, Robert W. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 801Donate, Amy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 107Donate, Amy L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 174Dondero, Richard . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 218Dong, Biao . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 310Dong, John Y.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 504, 643Dong, Xiaoyan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 376Donnelly, Eleanor M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 780Donovan, Kathleen A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 218Donsante, Anthony . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 24Dorer, Dominik E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 387, 641Doria, Monica. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 59, 64Dorko, K.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 139Doronin, Konstantin. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 496Doroudchi, Mehdi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 21Dorvault, Christine. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 834Dotti, G. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 30, 178

152American Society of Gene & Cell TherapyAbstract Author IndexDotti, Gianpietro . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 28, 288, 293, 472, 672Douglas, Joanne. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 834Douglas, Joanne T. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 507Dowdy, Sean C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 488Down, Julian D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 228Downey, Harre . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 546Downing, Brandon . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 353Doyon, Yannick . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 98Dragneva, Galina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 159Drescher, Charles . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 265Drescher, Max . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 843, 849Dropulic, Boro . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 527Du, Shi-Suo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 211Duan, Cathleen. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 872Duan, Dongsheng . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 150, 466,. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 587, 601, 707, 876Duan, Jiachuan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 433Duan, Xunbao . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 310Dubrot, Juan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 42Duckworth, Katherine . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 779Dudley, M. E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 31Dudley, Mark E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25Duffy, Angela . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 424Duffy, Aoife . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 427Dugin, Daniel P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 162Dumont, Nicolas . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 769Dunbar, Cynthia E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 96Dunfee, Ashley E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 96Dunn, Diane M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 152Dunn, Robert . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 181Dunphy, Nina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 277, 279Durett, April . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 288Duskey, Jason . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 594Dwyer, Markryan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 645Dylewski, Dawna . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 487EEagle, Michelle. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 314, 411Eaton, Laura . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 910Ebtekar, Massoumeh. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 871Edelman, Gerald . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 292Edmonson, Shyrie. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 548Edmonson, Shyrie E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 308Edwards, Paul C.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 104Eerola, Kim . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 145Eghtesad, Saman . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 580Egorova, Anna A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 750Ehrhardt, Anja . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 92, 141, 385, 636, 712Eiden, Maribeth V. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 696Eiermann, Jessica . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 314, 411Einfeld, David A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 504El Andaloussi, Samir . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 556Elgstrand Wettergren, Erika . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 239Elhalel, Michal . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 616Eliopoulos, Aristides G.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 486Ellis, James . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 300, 691El-Sherbini, Yasser M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 732Ely, Abdullah . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 82Emborg, Marina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 779Eming, Sabine . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5Emmanouil, Kalyopy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 405Enbersen, Johan F. J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 126Encinas, Tony . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 274Endo, Masayuki . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 320, 344, 676Engelhardt, John F. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4, 620, 698Engler, Tatjana . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 637Ennis, Matthew K. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 684Enoto, Kaoru . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 591Enríquez de Salamanca,. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Rafael42Enright, Annette . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 270Epperly, Michael . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 157, 514, 515Epperly, Michael W.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 580Erbacher, Patrick. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 883Erbs, Philippe . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 204Erez, Ayelet . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 677Erger, Kirsten . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 371Erger, Kirsten E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 378Eriksen, Jens . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 101Eriksson, Elof . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 237Eriksson, Minna . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 204Erker, Laura . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 910Ertl, Hildegund C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 389Escutenaire, Sophie. . . . . . . . . . . . . . . . . . 177, 197, 204, 291, 538, 549, 658Esfandiarifard, Saghi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 772, 794Essand, Magnus . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 501, 828Esser, Knud . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 312Evans, Claire F.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 162, 740Everhart, Drew . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17Ewert, Kai K. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 393FFabris, Marina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 258, 666Fadel, Hind . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 685Fagone, Paolo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 861Fakhfakh, Raouia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 784Falgowski, Kerry A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 897EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 153Abstract Author IndexFalk, Darin J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 596Falls, Theresa. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 39Falzarano, Sofia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 258, 666Fan, Bai . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 510Fan, Zheng . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 328Farag, Jacqueline . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 156, 454Fargnoli, Anthony . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 600Farini, Andrea. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 460, 464, 795Farley, Raymond. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 873Fassas, Athanasios . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 137Fast, Patricia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 162Favaro, Patricia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 614Federici, Thais . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 699, 778, 782Federoff, Howard J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 23Federspiel, Mark J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 490, 499Feduska, Joseph M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 629Feijen, Jan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 126Feldman, Steven A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25, 190Fellenberg, Kurt . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 641Fender, Pascal . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 843Fenelon, Gilles . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 777Feng, Jiazuo H. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 744Ferguson, Sherise D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 902Ferlini, Alessandra. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 258, 666Fernandes, Julio C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 756Fernandez, Christian A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 117, 594Ferrand, Maxime . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 48Ferrari, Giuliana . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 319, 523Ferro, Leda . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 911Ferry, Nicolas . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 138Fewell, Jason G.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 893Fidler, Jonathan A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 557Filipczyk, Adam . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 284Filippova, Elena . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 444Finegold, Milton . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 910Finn, Eric . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 461, 786Finn, Jonathan D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 43, 551, 614, 615Finney, Helene . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 845Fire, Andrew Z.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14Firozi, Pervez. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 574Fischbeck, Kenneth H. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 235Fischer, Alain . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 229Fishbein, Ariel . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 425Fishbein, Ilia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 323, 425Fisher, John T. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 620Fisher, Paul B. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 503, 847Fisher-Perkins, Jeanne . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 411Fisk, A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 697Fisk, N.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 223Flaat, Mette. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 314, 411Flageul, Maude . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 138Flake, Alan W. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 320, 344, 676Flanagan, Mike . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 105Flanigan, Kevin M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 152, 155, 789Flannery, John G. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 442Fleischhauer, Katharina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 295Fleischmann, Bernd. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 693Fletcher, Anita M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 776Florence, Julaine M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 152Flotte, Terence R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 51, 53Flotte, Terrence. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 444Flotte, Terry . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 58Foley, Jason. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 659Follenzi, Antonia. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 134Foloppe, Johann. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 204Fong, Mei . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 674Fons, Michael. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 289Fontanellas, Antonio . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 42Forde, Patrick F. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 736Forman, Stephen J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 555Fortes, Puri . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 249, 889Foster, Aaron E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 469, 816Foster, Edmund . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 451Foulad, David. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 181, 475Fowler, Daniel . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 341Fowler, Daniel H. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 333, 509, 659Fracchia, Sergio . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 276Fraix, Aurore . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 131Franicola, Darcy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 514Frank, Michael M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 638Frankel, Timothy L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 190Fransson, Moa . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 176, 453Frattini, Mark. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 32Frecha, Cecilia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 336Frelin, Lars. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 111, 289Frenkel, Niza . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 719Frey, Brigitte M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 855Frey, Felix J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 855Friedman, Geoffrey . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11Froehner, Stanely C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 584Froelich, Steven . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 689Fu, Yang-Xin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 517Fujita, Yuriko . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 288Fujiwara, Hiroshi. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 652Fukudome, Takayasu. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 585Fukunaga, Yoshitaka. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 680Furuya, Aki . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 824Fusaki, Noemi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 303, 634Futaki, Shiroh . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 246, 253, 401

154American Society of Gene & Cell TherapyAbstract Author IndexGGabant, Philippe . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 740Gabriel, I. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 777Gabriel, Richard . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 286, 347Gahan, Cormac G. M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 398Gahl, William A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 144Gaj, Thom . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 94Galanis, Evanthia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 170, 490, 499Galivo, Feorillo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 175, 481, 607, 610Galla, Melanie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 284, 302, 304, 619Galletti, Margherita . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 523Galloway, Gloria . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 290, 581Galton, Bruce . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 218Galun, Eithan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16, 616Galvan, Daniel . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12, 813Galy, Anne. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 48, 225, 229, 533, 552Gamble, Lena J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 842Ganea, Doina. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 859Gangadharan, Bagirath . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 230, 527Gangeswaran, Rathi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 605Gangopadhyay, Anu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 659Ganguli, Munia. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 127, 132Ganly, Sandra. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 439Gao, Dongling . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 605Gao, Guangping . . . . . . . . . . . . . . . . . . . . . . . . . 58, 362, 433, 450, 671, 759Gao, Ran. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 242Gao, Yongxin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 219, 518Garabedian, Elizabeth . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 296Garcia, Louis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 460Garcia, Luis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 154, 464, 795Garcia-Aragoncillo, Eva. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 494Gardiner, David F. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 162Gardmark, Truls . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 176Gardner, Matthew. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 608Gardner, Rebecca A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 618Garg, Harsha K. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 677Garg, Nupur . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 796Gargiulo, Annagiusi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 702Garibov, Mikhail . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 90, 529Gatti, Alessandra. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 276Gautney, Richard. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 527Gavrikova, Tatyana . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 497Gay-Antaki, Carlos. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 317Gaymalov, Zagit . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 817Ged, Cécile . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 865Gedeon, Christopher R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 445, 622Gee, A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 30Gee, Adrian . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 288Gee, Adrian P.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 293Gee, Samantha W. Y. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 700Geguchadze, Ramaz . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 371, 378Gehl, Julie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 101, 106, 109Geisert, Eldon E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 441Genovese, Pietro. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10, 88, 286, 632, 654Gentile, Antonietta . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 898Gentner, Bernhard. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 313, 331, 337Gerdemann, Ulrike . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 29, 473, 799Gerhardt, Greg A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 709Germain, Sean A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 596Gerritsen, Winald R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 40, 502Gersbach, Charles A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 94Geurts, Jeroen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 559, 627Ghaffari, Seyed Hamidolah. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 871Ghavamzadeh, Ardeshir . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 871Ghazi, Alexia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 470, 471Ghio, Domenico . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 295Giacca, Mauro . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 311, 423, 431Giachelli, Cecilia M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 730Giamarchi, Philippe . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 745Giangrande, Paloma H. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 662, 663Giannakopoulos, Aristeidis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 729Gianni-Barrera, Roberto . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 430, 597Giannoni, Francesca . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 522Gibbons, Hillary N. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 809Gibly, Romie F. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 764Gibson, K. M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 139Gibson, Soojung . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 417Giddings, Angela. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 881Giedlin, Marty . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 783, 798Giffear, Mary . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 477Giladi, Hilla . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16Gilbert, Rénald . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 463Gilbert, Richard A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 116Gill, Deborah R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 123, 727, 739, 880Gill, Steven . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 394Gillet, Danielle . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 120Gillet-Legrand, Beatrix . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 228Gilmour, Jill . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 162Gimble, Jeffrey. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 314Gimble, Jeffry . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 105Ginns, Edward I . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 418Giorgio, Todd D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 592Giovannoni, Roberto . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 59Giralt, Sergio . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 809Giridhara, Jayandharan R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 68Gissel, Hanne. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 106Giunti, Massimo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 59Giustacchini, Alice . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 337EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 155Abstract Author IndexGjetting, Torben . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 206, 511Gkirtzimanaki, Katerina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 486Glazer, Peter M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 50, 285Gleich, Bernhard. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 693Glimm, Hanno . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 347, 612Glorioso, Joseph C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 640, 781Glowacki, Julie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 157Gnatenko, Dmitri . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 372Gnecchi, M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 360Godbehere, Sarah S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 638, 651Goepfert, Christine . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 855Goerlich, Corbin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 243Goetzmann, Jason . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 58Goff, Julie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 514Goins, William F.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 640, 781Gokhale, Abhay . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 157Goldschlager, Gregg . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 38Goltzmann, Haim . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 616Gomero, Elida . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 449Gomez Almarza, David . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5González-Aseguinolaza, Gloria . . . . . . . . . . . . . . . . . . . . . . . . . . 485, 708, 810Gonzalez-Aparicio, Manuela . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 810Gonzalez-Rojas, Jovanna . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 889Good, Alec S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 125Goodheart, Michael J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 620Gopal, Kapil . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 156, 454Gopal, Vijaya . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 404Gorbatyuk, Marina S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 446Gorbatyuk, Oleg . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 378Gordley, Russell M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 94Gordon, Cath M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 880Goss, James R.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 781Gothelf, Anita. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 101Gotoh, Akinobu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 216Gotoh, Mitsukazu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 419Gotschalk, Stephen M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 816Gottfried, Lynn F. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 878Gottschalk, Stephen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 179, 293, 471, 656Gottschalk, Stephen M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 288Gottschalk, Steven . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 470Goudenege, Sebastien. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 769Gould, David . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 609Gräslund, Torbjörn. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 239Gröhn, Olli . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 159Gracey, Lia E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14Graham, John G. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 770Grande, Alexis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 523Grandi, Paola . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 640Grant, Rebecca L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 45Grant, Steven. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 503Grant, Trobridge D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 864Grassman, Elke . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 526Gray, John . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 222, 449, 733Gray, John T. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 354, 668, 860, 861Gray, Steven . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 581, 782Gray, Steven J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2Greco, Adelaide . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 847Green, Matthew D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 122, 125Greenberg, Philip D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 88, 654Greenberg, Richard . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 646Greenberger, Benjamin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 515Greenberger, Joel . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 157, 514, 515Greene, Michael R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 861Gregory, Philip . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 798Gregory, Philip D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10, 11, 88, 98,. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 286, 415, 618, 632, 650, 654, 801Greiser, Udo. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 439Grez, Manuel . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 869Grieger, Joshua C.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 160Griener, Dale . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 285Griesenbach, Uta . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 873Griffith, Graziella. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 154Griffiths, Duncan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 577Grilley, Bambi. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 288Grimm, Brad . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 571Grimm, Dirk . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 660, 886Grinstaff, Mark W. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 392, 744Gritti, Angela . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 316, 413, 632Grompe, Markus. . . . . . . . . . . . . . . . . . . . . . . . . 99, 306, 681, 682, 760, 910Gross, David-Alexandre . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 48Grossardt, Christian . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 833Grossman, Robert . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 471Grove, N.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 879Grove, Nathan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 75, 388Grove, Nathan C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 639Grover, Rajat . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 63Gruber, Harry . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 492, 831Gruenert, D. C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 913Gu, Shuo. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 54Gu, Yachuan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 566Guégan, Philippe . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 395Guérin, Claude . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 463Gualandi, Francesca . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 258, 666Guan, Jie. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 78, 114Gubinelli, Francesco . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 644Guedan Carrio, Sonia. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 496Guerin, Karen. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 442Gui, Tong. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 534

156American Society of Gene & Cell TherapyAbstract Author IndexGunset, Gertrude . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 655Gunther, William R.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 595Guo, Jianfeng. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 254Guo, Siqi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 107Gupta, Sanjeev. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 134Gürke, Lorenz. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 430, 597Gurram, Sweta. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 221Gurruchaga, Jean-Marc . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 777Guse, Kilian . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 204Gussing, Fredrik . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 239, 350Guttridge, Denis C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 635Guyonnet-Duperat, Véronique . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 865HHa, Yoon . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 260Haas, Andrew. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 33Haavisto, Elina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 177, 193, 197, 538, 658Habib, Bianca. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 603Hacein-Bey Abina, Salima . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 229Hacein-Bey-Abina, Salima. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13Hacker, Ulrich. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 664, 887Hackett, Neil R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19, 452Hackett, Perry B. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 325, 728, 734Hackl, Florian. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 237Hadac, Elizabeth. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 604Haddock, Courtney . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 213, 564, 578Haga, Kazunori. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 334Haghighatgoo, Arman . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 794Hahn, Woong. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 818Hai, Li. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 484Hai-Ying, Zeng . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 73Hajjar, Roger J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 601Hakkarainen, Tanja . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 204Halbert, Christine L.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 623Hall, Geoff. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 606Halle, Stephan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 284Hallek, Michael . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5, 312Hamada, Hiromi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 554Hamada, Katsuyuki. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 216, 493, 825Hamakawa, Hiroyuki. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 493Hamilton, Shari R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 308Han, Sang W.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 440Han, Seung Ryul. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 560Han, Sung Yeol . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 112Han, Tae Hee . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 85Han, Yu. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 902Hannah, William. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 534Hannaman, Drew . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 162, 740Hans, Skovgaard . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 206Hansel, M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 139Hansford, Loen. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 498Hans-Peter, Kiem . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 864Hantraye, Philippe . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 777Harada, Yui . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 824Haralambieva, Iana. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 170Harashima, Hideyoshi . . . . . . . . . 97, 240, 246, 253, 401, 591, 743, 748, 894Harding, Cary. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 681Hargrove, Phillip W.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 338, 339, 525Harms, Ashley S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 773Harper, John . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 158Harrington, Kevin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 606Harris, Drea . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 477Harris, Raymond D.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 36Harrison, Frank. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 408Harrison, Patrick T. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 705Harrow, Faith. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 521Hart, Brit J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 800Hart, Stephen L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 394, 747Hartman, Zachary C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 638Harty, C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 194Harvey, Brandon K. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 709Hasegawa, Mamoru . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 303, 634, 824, 873Haseley, Amy. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 836Hashimoto, Takuya . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 891Haskins, Mark . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 758Haskins, Mark E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 598, 759Hatakeyama, Hiroto . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 246, 253, 894Hatano, Norikazu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 678Hatefi, Arash . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 329Hattori, Kayoko . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 862Hauer, Julia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 617Haugwitz, Michael . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 674Haurigot, Virginia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 546, 885Hausl, Martin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 636Hausl, Martin A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 385, 712Hauswirth, Wiliam W. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 417Hauswirth, William W.. . . . . . . . . . . . . . . . . . . . . . . . . . . . 17, 21, 61, 71, 446Hawkins, Troy B. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 353, 356Hawley, Robert G.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 342, 690Hawley, Teresa S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 342, 690Haworth, Kevin G.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11Hay, John G. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 713Hayashi, Hiroki. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 774Hayashi, Yasuhiro . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 743Hayes, John. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 155He, Bo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 683He, Cheng-Yi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9He, Ran. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 58, 362, 450, 671EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 157Abstract Author IndexHe, Shuhui . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 130He, Xianghui . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 186, 566Hearing, Patrick . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 372, 573Hebel, Henry . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 576, 739Heberer, Michael. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 430, 597Heckl, Dirk. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 318Heemskerk, Hans A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 153Hegadorn, Carol . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 767Hegge, Julia. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 160Heinonen, Suvi. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 159Heinz, Niels . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 302, 619Heldermon, Coy D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 768Helfer, Brooke . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 271Heller, Loree . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 116, 823Heller, Richard . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 107, 174, 823Helminen, Andreas . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 197Hemmi, Silvio . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 193Hemminki, Akseli . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 177, 193, 197,. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 204, 291, 538, 549, 657, 658, 843Hemminki, Otto . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 193Hensel, Jonathan A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 63Heo, Kyun . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 386Hermonat, Paul L.. . . . . . . . . . . . . . . . . . . . . . . . . . . 429, 436, 437, 711, 819Hernandez-Alcoceba,. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .Ruben 494, 810Hershfield, Michael S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 296, 678Hervás-Stubbs, Sandra. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 42Hervas-Stubbs, Sandra. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 810Herzog, Erik. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 768Herzog, Roland W. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 309, 363, 539, 540Heslop, Helen E.. . . . . . . . . . . 28, 29, 30, 178, 288, 293, 470, 471, 473, 799Hewitt, Stephen M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 659Hiatt, P.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 879Hibbitt, Olivia C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 602Hicks, Martin J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 452, 752Hicks, Martin L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 161Hickstein, Dennis D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 234, 524, 858Higashimoto, Tomoyasu. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 526Higgins, Luke J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 214Higgs, Jerome T.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 63High, Katherine A.. . . . . . . . . . . 8, 43, 69, 308, 546, 548, 614, 615, 630, 673Hikichi, Mina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 34, 840Hinderer, Christian. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 412Hintze, Thomas H. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 423Hinzman, Jason . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 709Hiraoka, Kei. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 334, 492, 831Hiroshima, Kenzo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 851Hirsch, Matthew . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2Hiscott, John . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 39Ho, David D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 162Ho, Seong-Hyun . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 818Hodge, Gregory . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 168Hodgson, Clague P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 166, 572, 575, 738Hoel, Brian D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 504Hoesel, Marianna . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 312Hoffer, Barry J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 709Hoffman, Brad E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 539Hoffman, Eric. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 56Hoffmann, Ellen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 886Hoffmann, Victoria . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 135Hofmann, Lawrence V.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 214Hoheisel, Jörg . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 641Hojman, Pernille. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 101, 106Hole, Patrick . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 577Hollis, Roger . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 522Holmes, Michael. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 798Holmes, Michael C.. . . . . . 10, 11, 88, 98, 286, 415, 618, 632, 650, 654, 801Holt, Nathalia G.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11Holtrup, Frank . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 641Holtz, R. B. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 213Hondmann, Dirk H. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 332Hong, Seung Hwa. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 112Hong, Youngtae . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 818Hoogstraten-Miller, Shelley. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 144Horowitz, Eric D.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 403Horsager, Alan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 21Horton, Terzah M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 473Horvath, Staci . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 196Hosoyama, Sachiko O. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 151Hoti, Naser Uddin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 382Hotta, Akitsu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 691Hou, Linan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 186Hough, Christine. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 767Hovhannisyan, Ruben . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 625Howard, Candace . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 847Howard, Douglas B. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 709Howard, Linda . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 270Howard, Jr, James . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 328Hricak, Hedvig . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 185Hsieh, Chia-Ling . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 844Hsieh, Matthew M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 352Hsieh, Ming Kun. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 173Hsu, David. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 277, 279, 905Hu, Biliang. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 686Hu, Chuhong . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 44, 224, 373Hu, Chunling . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 685Hu, Chunyan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 433Hu, Huimin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 449

158American Society of Gene & Cell TherapyAbstract Author IndexHu, Jim . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 872Hu, Yu-Chen. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 583Hua, Yimin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 55Huang, Chienjin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 173Huang, Jing-Hua . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 202, 811Huang, Yaoxing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 162Huard, Johnny . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 456, 629, 635Hughes, Jeffrey A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 256, 775Hui, Daniel J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 43, 546Huizing, Marjan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 144Huls, Mary H.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 479Humala, Nelson . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 38Humblet-Baron, Stephanie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 343, 529Humeau, Laurent . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 41Humeau, Laurent M. . . . . . . . . . . . . . . . . . . . . . 165, 422, 797, 800, 802, 803Humphries, Margaret. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 444Humphries, R. Keith . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 631Hung, Gene . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 55, 557Hung, Mien-Chie. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 844Hunter, Michael J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 524Hurley, Arlene. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 162Hurton, Lenka . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 479Huston, Marshall W. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 530Hutson, Thomas . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 451Huye, Leslie E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 472Huyn, Steve. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 714Hwang, Esther . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 796Hwang, Gloria L.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 214Hwang, Mark E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 119, 595Hwang, T. C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 876Hwang, Taeho . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 33Hyatt, Susannah L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 445, 622Hyde, Stephen C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 123, 727, 739, 880Hyland, Kendra A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 868Hynes, Sean O. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 439Hyvärinen, Anna. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 212, 512IIacobelli, Nicholas. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 615Iankov, Ianko D.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 170, 490Ichikawa, Tomohiko . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 824Iida, Akihiro . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 303Ikeda, Alan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 296Ikeda, Hiroaki . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 652Ikeda, Yasuhiro . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 599, 633, 688Ikoma, Akihiko. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 862Ilett, Elizabeth . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 481Ilies, Marc A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 757Inagaki, Akihito . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 334, 492, 831Ino, Yasushi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 832, 839Inoue, Hiroyuki. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 192, 263Inoue, Makoto . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 303, 634, 824, 873Inoue, Tomoko . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 263, 899Iodice, Carolina. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 443Ironside, Christina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 864Irrazábal, Thergiory. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 766Isaksson, Christina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 350Ise, Kazuya . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 419Ishida, Eri . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 513Ishihara, Kazuhiko . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 743Ishii, Takehiko . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 118Ishii, Yuko . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 102Ishiwata, Akira . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 421, 544Ismail Nounou, Mohamed M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 405Itaka, Keiji. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 118, 891Ito, Erika . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 253Ito, Mikako . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 585Ito, Takayuki . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 428Ito, Tomoko . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 749, 825Ivanovska, Irena. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 357Ivics, Zoltan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 302Iwamoto, Mari . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 350Iwata-Kajihara, Tomoko . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 480Izmiryan, Araksya. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 87Izsvak, Zsuzsanna . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 302JJaffrès, Paul-Alain . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 131, 745Jagadeesh, Jayashree . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 296James, Scott E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 558Jan, Caroline . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 777Janda, Kim D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 161, 452, 752Janicki, Hanna . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 312Janik, J. E.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 31Janjic, Jelena . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 271Jarraya, Bechir . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 777Jasti, Aparna . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 353, 675Jay, Chris. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 144Jay, Chris M. . . . . . . . . . . . . . . . . . . 148, 245, 247, 252, 532, 564, 578, 586Jayandharan, Giridhara R. . . . . . . . . . . . . . . . . . 363, 369, 370, 700, 704, 706Jegga, Anil G.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 830Jenkins, Kristy M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 79Jensen, Bryan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 910Jensen, Michael C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 618Jensen, Thomas G. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 787Jeong, Hwa Yeon . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 128, 406, 754Jeong, Jae-Gyun . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 818Jeong, Jin-Sook . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 560EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 159Abstract Author IndexJeong, Myung Ho . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 399, 751, 900, 904Jian, Zhou . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 73Jiang, Guozhong. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 605Jiang, Haixiang. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 638Jiang, Jiangjang . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 420Jiang, Shuguang. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 798Jiang, Xuan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 124, 321Jiang, Ziyue . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 850Jibly, Tamar . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 616Jikimoto, Takumi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 167Jimenez, Veronica. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 762Jin, Jiankang . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 243Jin, Xiangyang . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 414Jno-Charles, Odella . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 625Joensuu, Tiimo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 538Joensuu, Timo . . . . . . . . . . . . . . . . . . . . . . . . . 177, 193, 197, 291, 549, 658Joergensen, Mette . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 109Joh, Ju . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 163Johana, N.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 697John von Freyend, Miriam . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 312Johnson, Adam J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 330Johnson, R. Paul. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 645Johnson, Shane . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 576Johnston, Jennifer M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 230Johnston, Julie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 625Jollet, Arnaud. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 87, 617Jolly, Douglas. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 492, 831Jones, David . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 416Jonker, Derek. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 33Jonlin, Erica . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 137Joung, J. Keith . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 95Judge, Luke . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 466Judge, Luke M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 459Juliano, Rudy L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 62June, Carl H. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 341, 798, 801, 809Jung, Jae Wook . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 877Jung, Kyeong Cheon . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 406Jung, Maria C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 289Junghans, R. P.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 827Junghans, Richard P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 27, 182Jungmann, Andreas. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 241KKabanov, Alexander V. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 817Kabashima, Kenji . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 862Kabir, Farruk M. L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 379Kacherovsky, Nataly A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 730Kaeppel, Christine . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 138, 305Kafri, Tal . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 355, 534Kaikkonen, Minna U.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 209Kaja, Aparna . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12Kakeda, Minoru . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 236Kakimoto, Shinji. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 397Kaler, Stephen G. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 24Kalsi, Jasmine K. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 700Kaluza, Karen. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 175Kamau, Erick . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 645Kamen, Amine . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 361Kamijima, Shuichi. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 334Kamimura, Kenya . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 322Kaminsky, Paul M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 698Kaminsky, Stephen M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 161, 452, 752Kamiya, Hiroyuki . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 97, 240Kanai, Ryuichi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 608, 829Kanda, Genki . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 240Kaneda, Yasufumi. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 187, 628, 774Kanerva, Anna . . . . . . . . . . . . . . . . . . . . . . . . . 193, 204, 291, 538, 549, 658Kang, Bum-Yong. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 437Kang, Chang-Yuil . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 818Kang, Elizabeth M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 354Kangasniemi, Lotta . . . . . . . . . . . . . . . . . . . . . . . . . . 177, 291, 538, 549, 658Kano, Mitsunobu R.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 891Kao, Chinghai. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 334Kaplan, David. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 498Kapoor, Neena . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 296Kapp, Kerstin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 189, 822Kappel, C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 223Karandish, Sara . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 342Karioja-Kallio, A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 538Karlen, Andrea . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 221Karlen, Andrea D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 232Karli, Eerika . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 658Karlsson, Hannah . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 83Karpati, George . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 463Karponi, Garyfalia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 137Kasahara, Nori . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 200Kasahara, Noriyuki . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 334, 492, 500, 831Kasahara, Yuko N. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 151, 582Kaskenpää, Nina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 159Kassim, Sadik H. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1, 412Kasuda, Shogo. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 903Kataoka, Kazunori . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 118, 891Katayama, Kazufumi. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 537Katayama, Takane . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 167Kato, Junko . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 903Katoono, Ryo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 401Katovich, Michael J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 518Katus, Hugo A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 241, 432

160American Society of Gene & Cell TherapyAbstract Author IndexKatz, Michael G.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 600Katzenberg, Regina H.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 214Kaul, Sunil C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 242, 841Kaur, Balveen. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 199, 836Kaushal, Shalesh . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 444Kauss, Ariel . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3Kaverina, Natalya V. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 835Kawabata, Kenji . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 537Kawabata, Masato . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 167Kawakami, Yutaka . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 480Kawamura, Kiyoko . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 851Kawamura, Nobuaki . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 678Kawanishi, Yu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 513Kawano, Hirotaka. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 263, 899Kawasaki, Yoshiko . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 500Kay, Jennifer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 794Kay, Mark A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9, 14, 54, 306, 682, 760Kaynor, G. Campbell . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 517Kaza, Niroop . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 63Kazuki, Yasuhiro. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 236Keating, M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 30Kehry, Marilyn . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 550Keiser, Nicholas W. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4, 698Kemmerrer, Stephen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 103Kemmerrer, Steve. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 327Kennedy-Nasser, Alana. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 288Kerkard, Sid P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 478Kerns, Hannah M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 343Kerr, Douglas A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 908Keshavjee, Shaf . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 872Keswani, Rahul K.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 119Kettlun, Claudia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12Kew, Yvonne . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 471Khan, A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 648Khan, Amir. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 103, 115, 477Khan, Junaid A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 429, 436, 437Khanduri, Richa . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 132Khargharia, Sanjib . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 117, 594Khazi, Fayaz . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 310Khim, Jit . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 529Khokher, Zeshan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 772, 794Kholová, Ivana . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 159Khoury, Maroun . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 531Kichler, Antoine. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 67, 400, 791Kida, Miyuki. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 678Kidokoro, Minoru . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 34, 840Kiem, Hans-Peter . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 294, 631, 909Kim, Dong-Eun . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 895Kim, Dongho . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 257Kim, Dong-Sik . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 818Kim, Eun Ok . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 386Kim, Hong Sung . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 406, 754Kim, Hyun-Ki . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 896Kim, In-Hoo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 384, 386Kim, Inwook . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 242Kim, Ji-seong . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 188Kim, Jong-Mook . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 818Kim, Joo-Hang . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 202, 257Kim, Jung Seok . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 128, 406, 754Kim, Kenneth . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11Kim, Kenneth H. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 36, 503Kim, Keun Sik . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 406, 754Kim, KeungNyun. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 260Kim, Keun-Sik . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 128Kim, Kwang-il. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 805Kim, Kyungbo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 895Kim, Min jung . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 560Kim, Nahyun . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 407, 877Kim, Nam Hee . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 722Kim, Pyung-Hwan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 86Kim, S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 913Kim, So Y. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 257Kim, Sue Kyung . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 386Kim, Sujeong . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 818Kim, Sung Wan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 86, 126Kim, Sunyoung. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 818Kim, Tae-il . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 86Kim, Yong Oock . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 516Kim, Yong Sook . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 399, 751, 900, 904Kim, Yoon-Sang . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 338, 339, 861Kim, Yun-Hee . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 386Kimball, Kristopher J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 834Kimmelman, Jonathan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 779Kimura, En. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 468, 788Kimura, Takahiro. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 334Kinder, Clifford . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 646King, Gwendalyn D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 26King, Wendy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 155Kingsman, Susan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 777Kinoh, Hiroaki . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 824Kinoh, Hiromi H.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 151, 582Kinoshita, Shohiro. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 167Kirn, David H.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 33, 39Kiselev, Anton V.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 750Kisling, Lisa A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 759Klanke, Chuck . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 830Klein, Christoph . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 612Kleinschmidt, Jürgen A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 241, 432EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 161Abstract Author IndexKleuss, Christiane . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 189Kliem, Michele A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 778Klimczak, Ryan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 299Klimczak, Ryan R.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 442Klump, Hannes. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 284Kmiec, Eric B.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 569, 897Knoblauch, Christine . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 277, 279Knolle, Percy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 312Knop, David R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 377, 571Kobasa, Darwyn . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 169Kobayashi, Hiroshi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 851Kobayashi, Ryouji . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 678Kobinger, G.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 648Kobinger, Gary . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 64Kobinger, Gary P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 169, 724Koch, Walter J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 600Kochanek, Stefan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 637Kochenderfer, J. N. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 31Kocis, Keith . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 328Koeberl, Dwight D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 47, 136, 142Koefoed, Mette . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 787Koerber, James T. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8Kofod-Olsen, Emil . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 91Kohn, Donald B. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 296, 414, 522Koibuchi, Nobutaka. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 774Koide, tatsuya . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 468Koike, Kazuo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 890Kok, Cindy Y. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 409Kokkinou, Dimitra. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 729Koldej, Rachel M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 867Kole, Ryszard. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 56Kolstad, Kathleen D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 442Komanduri, Paavani . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 515Komatsu, Norio . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 263Kondratenko, Irina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 612Kong, Seogkyoung . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 182Kong, Weiming. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 859Koniar, Brenda L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 728Konieczny, Patryk . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 786Konno, Tomohiro . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 743Konstantinova, Pavlina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 249, 255Kontermann, Roland . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 387Koorneef, Annemart . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 255Koornneef, Annemart . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 249Kopp, Lisa M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 479Kopyov, Oleg . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 912Kornegay, Joe . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 454, 467, 785Kornegay, Joe N. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 790Kornegay, Joseph . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 458Korokhov, Nikolay. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 165, 422, 797, 800Korpisalo, Petra . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 159Koski, Anniina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 177Kota, Janaiah. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 155Kotchey, Nicole M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7, 703Kothary, Nishita . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 214Kottke, Timothy . . . . . . . . . . . . . . . . 175, 481, 496, 606, 607, 610, 611, 653Kouyama, Emi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 537Kowalczyk, Tomasz H.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 445, 622, 776Koyama, Hiroyuki . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 891Koyama, Taro. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 237Koyama, Yoshiyuki . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 749, 825Kozink, Daniel M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 142Kozyak, Benjamin. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 156, 454Kraaij, Robert. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 506Krahn, M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 460Krainer, Adrian R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 55Krance, Robert A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 288Krasnykh, Victor . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 725Krause, Anja. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 163Krause, Johanna. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 318Krejci, Eric . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 585Kremer, Eric . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 570Kremer, Eric J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 573Kreppel, Florian . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 637Krichevsky, Anna M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 665Kroeger, Kurt . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 181Kroeger, Kurt M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 26, 475Kron, Matthias W.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 637Ksienzyk, Jan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 432Kuang, Chenzhong . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 332Kuball, Jurgen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 88, 654Kubo, Shuji . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 500Kudrolli, Tarana A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 390Kudva, Yogish . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 633Kuehle, Johannes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 284Kühlke, Klaus . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 612Kuhn, Joseph . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 275, 292, 335, 532Kulkeaw, Kasem. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 263Kumagai, Izumi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 640Kumar, Padmasini. . . . . . . . . . . . . . . . . . . 245, 275, 292, 335, 487, 532, 564Kumar, Priti . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 285, 407, 877Kumar, Sanjay . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 906Kumar, Sanjeev . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 250Kumar-Singh, Rajendra . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 447, 448Kume, Akihiro . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 207, 421, 428, 544, 554Kupiec, Martin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16Kurachi, Shinnosuke . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 537Kurita, Ryo. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 263, 899

162American Society of Gene & Cell TherapyAbstract Author IndexKurre, Peter . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 692Kurtova, Antonina V. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 469Kusano, Eiji . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 428Kushmeric, Martin. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 553Kustikova, Olga S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 619Kuwahara, Hiroya . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 259Kwon, Jin Sook . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 399, 751, 900, 904Kwon, Oh Seok . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 112Kyrtatos, Panos . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 394LLab, McIvor . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 221Labelle, Andrea. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 767Labruna, Giuseppe . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 435Lachmann, Nico . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 528Laflamme, Karina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 521Lagadinou, Eleni . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 340Lago, Natalia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 451Lagresle-Peyrou, Chantal . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 617Laguzzi Larcher, Fernando . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5Lai, Frances . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 39Lai, Yi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 150, 466, 587Laidinen, Svetlana . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 159Lainé, Céline . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 120Laing, Jennifer M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 273, 717Laitinen, Anna E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 669Laitinen, Lauri M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 669Lakshmipathy, Uma . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 268Lalanne, Magalie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 865LaManna, Caroline M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 744Lamarre, Yann . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 769Lamm, Don . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 35Lamrissi-Garcia, Isabelle . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 865Landry, Breanne . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 129, 755Langan, Russell C.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25Langel, Ülo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 556Lapteva, Natalia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 474Larcher, Fernando . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 158, 351Larochelle, Andre . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 96Larochelle, Nancy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 463Lattanzi, Annalisa . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 413Lau, Ashley . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 306Laure, Aurelian . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 273Laurema, Anniina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 765Lavasani, Mitra. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 629, 635Lavasanifar, Afsaneh . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 568Lavie, Arnon. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 333Lavilla-Alonso, Sergio. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 193Lavitrano, Marialuisa . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 59Lawler, Sean . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 498Lawson, Alastair . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 845Lawton, Anna E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 727Lay, Fides D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 44, 224, 373Layman, John M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 125Lazaris, Vassileios . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 729Le, Yun . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 417Le Boeuf, Fabrice . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 37, 39Le Gall, Tony . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 120, 131, 395, 745Le Guiner, Caroline . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 305, 365Le Hir, Maëva. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 154Lebel-Binay, Sophie. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 110, 113, 853LeBlanc, Katarina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 453Leborgne, Christian . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 400Leboulch, Philippe. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13, 228Leddon, Jennifer L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 201Lee, A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 913Lee, Andrew Y. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 910Lee, Bokhui . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 895Lee, Brendan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 46, 224, 309Lee, Brendan H. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 677Lee, Chang J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 522Lee, Dean A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 479Lee, Donghoon. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 553Lee, Fan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 558Lee, Gabsang . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 283Lee, Gary. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 783, 798Lee, Hwang-Jae . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 818Lee, Il-Kyu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 516Lee, Jessica . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 477Lee, Jung-Sun . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 720, 841Lee, Kyung-Mi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 167Lee, Lily . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 674Lee, Meng Horng . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 282Lee, Mi-Hyang . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 384Lee, Mingul . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 202Lee, Sang kyung. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 877Lee, Sang-Jin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 384Lee, Sang-Kyung. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 407Lee, Seong-Wook . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 560Lee, Suhung . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 257Lee, Won Il . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 560Lee, Yeon Jyung . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 406Lee, Yeon Kyung. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 128, 754Lee, Yong J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 257Lee, Young Ju . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 560Lee, Young Won . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 126Lee, Young-Sook. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 198Leen, Ann . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 179, 471EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 163Abstract Author IndexLeen, Ann M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 29, 473, 799Leger, Adrien . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 305, 365Leggiero, Eleonora . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 435Lehn, Pierre . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 120, 131, 395, 745Lei, Pedro . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 358, 359Lei-Butters, Diana . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4Leif, Jean . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 285Leja, Justyna . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 501, 828Lekka, Malgorzata . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 533Lemiale, Franck . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 41, 165Lemiegre, Loic . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 120Lemoine, Nick R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 605Lenander, Andrew W.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20Lenne, Nathalie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 883Leon, Xavier. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 762Leonard, Helen Paige . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 411Leonard, Vincent. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 168Leong, Derek . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 321Lepetit, Helene. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 777Lerario, Alberto. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 795Lesch, Hanna P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 209, 669Lesniak, Maciej S.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 191, 718, 835, 902Leung, Anders . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 169Leung, Cary H. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 778, 782Leung, Kitty . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 872Levine, Bruce . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 341, 798Levings, Megan K. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 79Lévis, Nicolas . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 460Levy, Camille . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 336Levy, Robert J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 323, 425, 753Lewin, Alfred . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 61Lewin, Alfred S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 417, 446Lewis, Sarah . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 155, 290, 581Leyfman, Yan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 266Li, Baozheng . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 369, 704Li, Chengwen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 160, 366, 367Li, Chengwin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 581Li, Chengyao . . . . . . . . . . . . . . . . . . . . . . . . . . 171, 518, 806, 807, 808, 854Li, Dejia. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 466, 707Li, Haitang. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 287Li, Hojun . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 308Li, Hongtao . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 203Li, Hongwei . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 219, 518, 854Li, Hui. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 412Li, Jianfeng . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 484Li, Juan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6, 160, 420, 581, 683Li, Linhong. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 675Li, Mengxin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 58, 369Li, Min . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 876Li, Pingchuan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 85Li, Quanhai . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 851Li, Shulin. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 105, 484, 737Li, Songtao . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 142Li, Tingting. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 171, 806, 807Li, Wei . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 890Li, Weidong . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 186Li, Wuping. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2Li, Xiaohong. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 130Li, Xiaozhu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 605Li, Yan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 603Li, Yi. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 234Li, Yong. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 456, 465Li, Yong-Fu. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 49Li, Yuedan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 617Li, Zhixiong . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 619Li, Zhong. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 68Li, Zong. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 657Li, ZongYi . . . . . . . . . . . . . . . . . . . . . . . . . . . . 180, 264, 265, 843, 849, 863Lichty, Brian D.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 39Lidonnici, Maria Rosa . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 523Lieber, Andre . . . . . . . . . . . . . . . 93, 180, 264, 265, 415, 657, 843, 849, 863Lieberman, Jay R.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 687Liesner, Raphael . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 92Liggitt, Denny. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 343Liikanen, Ilkka . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 204Likar, Yury . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 185Liles, Conrad . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 907Liljenfeldt, Lina. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 820Liljenfeldt, Lina S. E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 486Lillicrap, David . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 767Lim, Arlene T.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 418Lim, Carol S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 205Lim, Kwang-il . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 299Lim, Sung-Won. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 818Lima de Silva, Maria . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 479Limberis, Maria P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 625Lin, Amy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 411Lin, Chao. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 126Lin, Chin-Yu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 583Lin, Chung-Ren . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 882Lin, Feng. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 103, 115, 327Lin, Kun-Ju. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 583Lin, Patricia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 26Lin, Xiaojing. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 694Lindberg, Mattias . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 120, 131Lindholm, Leif . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 506Lindqvist, Camilla . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 83Lindqvist, Camilla A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 176

164American Society of Gene & Cell TherapyAbstract Author IndexLindsey, Matt . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 281Ling, Chen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 369, 700, 704, 706Linton, Gilda M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 354Lionetti, Vincenzo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 423Lipshutz, Gerald S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 44, 224, 373Lisowski, Leszek. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 306Liu, Chao-Lien. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 535Liu, Chunyan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 181Liu, Dexi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 100, 108, 322, 484Liu, E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 30Liu, Elaine . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 783Liu, Enli. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 288, 293Liu, Hao . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 288, 293Liu, Jian W. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 417Liu, Jian Wen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 21Liu, Joyce C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 651Liu, Meihong . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 696Liu, MengLu. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 260Liu, Minzhi M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 390Liu, Pei-Qi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 88Liu, Shihe . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 247, 564Liu, Shi-he . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 892Liu, Xiaoming. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 620Liu, Xiaoxuan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 287Liu, Xiuying . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 662Liu, Ying . . . . . . . . . . . . . . . . . . . . . 180, 264, 265, 415, 657, 843, 849, 863Liu, Yong. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 429, 436, 711Liu, Yunfan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 238Liu, Zhao-Jun . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 603Liu, Zhongda . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 218Llewellyn, J. Anthony . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 116Lo, Mandy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 300Lo, Mandy Y. M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 691Lo, Wen-Yi. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 583Lock, Martin W. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 45Lockey, Timothy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 861Logg, Christopher R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 334, 831Loh, Y. P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 143Loiler, Scott A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 66, 231Loiseau, Damien. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 745Lollar, Pete . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 527Lombardo, Angelo. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10, 88, 286, 632, 654Long, Timothy E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 122, 125Lopez, Patricia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 277, 279Lopez, Teresita . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 288Lopez, Veronica M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 609, 834Lorain, Stéphanie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 154Lorilleux, Christophe . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 131Lorini, Alessandro . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 276Lorson, Christian L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 626Loskog, Angelica S. I. . . . . . . . . . . . . . . . . . . . . . . . . . 83, 176, 453, 486, 820Lotta, Louis T.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 76Lou, Rongcheng . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 819Louie, Stan F.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 522Lovric, Jasmina. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 311Low, David. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 156Low, Walter C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20Lowe, Andrew S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 394Lowe, Michelle C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 592Lowenstein, Pedro R.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 26, 181, 475Lu, Aiping . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 629, 635Lu, An. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 469Lu, Hui . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 310Lu, J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 697Lu, Jian . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 114Lu, Jing. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 65Lu, Peijuan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 890Lu, Qi Long . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 890Lu, Taihe . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 222, 860Lu, Yi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 217Lu, You . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 433Lu, Yuan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 700, 704, 706Lu, Yuanqing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 375Lu, Zhuoyuan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 405Lucarelli, Guido. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 319Luchetti, Andrea . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 908Lukacs, Gergely . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 620Lukashov, Vladimir . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 797Luke, Jeremy M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 166, 572, 575, 738Lulay, Christina. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 612Lundberg, Cecilia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 239, 350Lundberg, Kathryn. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 107Luo, Chia-Hsin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 583Luo, Mathew . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 277, 279Luo, Meihui . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 620Luo, Min . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 504Luo, Xianghua . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 497Luo, Xiaoyan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 142Luo, Yonglun . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 91Lupo Stanghellini, Maria Teresa. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 295Lupold, Shawn E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 251, 390Lusic, Hrvoje . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 744Lusky, Monika . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 204Lust, John A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 218Lüttge, Doreen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 528Lv, Chengyu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 566Lyon, Deborah . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 288Lythgoe, Mark . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 394EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 165Abstract Author IndexMMa, Hong . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 355, 534Ma, Jianjie. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 683Ma, Qiangzhong. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 27Ma, Wenqin. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 369, 704Ma, Yongjie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 100Ma, Zhijun. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 860Määttä, Ann-Marie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 209Macauley-Rambach, Shannon L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 22Machen, Laurie. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 104Machleidt, Thomas . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 268Maciotta, Simona . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 464, 795MacTavish, Heather. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 39Maczuga, Piotr. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 255Mader, Emily K. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 488Maderna, Claudio . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 413Madigan, Nicolas N. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 780Madoiwa, Seiji . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 421, 544Madtes, David K. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 623Maeda, Michiko W.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 151Maeda, Tadao . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 445Maeda, Yasushi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 468, 788Maeder, Morgan L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 95Maetzig, Tobias . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 284, 302, 619Maeyama, Yoshihiro . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 678Magee, Mitchell . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 292Magnani, Zulma . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 88, 654Magnusson, Maria K. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 506Maguire, Casey A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 57Maguire-Zeuss, Kathleen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 23Mah, Cathryn S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 596Mahan, John D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 155Mahato, Ram I. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 84, 741Mahller, Yonatan Y.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 830Maier, Dawn . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 798Maisner, Andrea . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 336Maiti, Sourindra . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 479Makarevich, Pavel. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 434Makino, Hirofumi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 884Malani, Nirav . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13, 228, 283, 308, 346Maldonado, Arturo R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 830Malech, Harry L.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 220, 354, 688, 860Malgieri, Arianna . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 908Malik, Alock. . . . . . . . . . . . . . . . . . . . . . . . . . . 156, 374, 454, 458, 467, 785Malik, Punam. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 280, 526, 864Malik, Vinod . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 149, 155, 290, 581Malloy, Andrew . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 577Malmstrom, Per-Uno . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 176Mamchaoui, Kamel . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 789Mamdani, Mohammed . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 423Mancheño, Uxua . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 42Manchengo, Uxua. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 810Mandel, Ron . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 147Mandelli, Giacomo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 319, 523Mangopoulos, Kathryn. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 280Mangsbo, Sara M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 176Mangus, Courtney. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 341Mani, Sendurai. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 243Maniar, Jay M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14Mann, Anita. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 132Mann, Derek A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 716Mano, Miguel. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 311Manoli, Irini . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 135Mansfield, S. Gary . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 422Manunta, Maria D. I.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 747Mao, Hai-Quan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 124, 321Mao, Haoyu. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 446Maples, Phil. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 144Maples, Phillip B. . . . . . . . . . . . . . . . . . . 148, 213, 245, 247, 248, 252, 275,. . . . . . . . . . . . . . . 292, 335, 487, 520, 532, 564, 574, 578, 586, 731, 892Maródi, Laszló . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 612Marano, Giuseppina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 276Marasco, Wayne A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 645Marc, Lavertu. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 396March, Keith L.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 630Marchadier, Dawn. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 412Marcucci, Katherine T. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 630Marerro, Bernadette . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 823Marianowski, Rémi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 120Maric, I. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 31Marigo, Valeria. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 624Marin, Virna. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 845Marinkovich, Peter M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 320Marion, Patricia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 82Marjomäki, Varpu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 159Markley, John C.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 655Marktel, Sarah . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 319Markusic, David . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 371Markusic, David M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 540Marongiu, F.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 139Marrocco, Elena . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 624Martelli, Letizia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 276Martin, Fernando L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 599Martin, William . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 43Martinez, Caridad . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 288Martino, Ashley . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 540Martino, Ashley T.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 309, 363, 539Martino, Sabata . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 313, 316, 413

166American Society of Gene & Cell TherapyAbstract Author IndexMartuza, Robert L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 608, 829Maruggi, Giulietta . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10, 319, 346Marumoto, Tomotoshi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 263, 899Maruyama, Kazuo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 102Masatoshi, Ishizaki . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 788Maslyar, Daniel. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 35Mason, A. James . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 400Massariello, Paola. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 276Massey, Paul . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 659Massie, Bernard . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 463Mastrangelo, Michael A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 18Masuda, Akio. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 585Masuda, Tomoya . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 591, 743Masurier, Carole . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 67, 791Matar, Majed . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 893Mathiesen, Iacob . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 289Matsui, Chihiro. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 320Matsui, Hideto . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 767Matsumoto, Hiroshi. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 492, 831Matsumoto, Tae . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 680Mattar, C. N. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 223, 697Mattar, Citra. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 531Matteo, Benjamin C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 21Matthews, Qiana L.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 842Mätzig, Tobias . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 304Mauleón, Itsaso . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 42Mauleon, Itsaso . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 810Mavilio, Fulvio . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10, 319, 346, 351, 523Mayer, Christina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 683Maynard, Jonathan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 85Mays, Lauren E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1Mazur, Curt . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 557Mazurier, Frédéric . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 865Mazzaccara, Cristina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 435Mazzieri, Roberta . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 331McAlister, Victor J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 70, 710McCants, Marjorie. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 314, 411McCarty, David . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 814McCarty, Douglas M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 307McChesney, Michael . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 168McClure, Diane. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 893McConnell, R.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 879McConnell-Smith, Audrey . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 89McCormick, Dominique . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 880McCown, Thomas J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2, 355, 366McCoy, Jay . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 103, 327McCullagh, Karl . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 439McDonald, Robert A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 380McDonough, Samantha . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 80, 505McGarrity, Gerard . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 41, 646, 803McGarrity, Gerard J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 274, 422McGinley, Lisa . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 427McGoogan, Katherine E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 700McHugh, Peter . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 439McIntosh, J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 223McIvor, R. Scott . . . . . . . . . . . . . . . . . . . . . 868, 20, 221, 232, 325, 734, 852Mckenna, Mavis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 58Mckiernan, James. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 35McKown, Thomas J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 778McLachlan, Gerry . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 880McMahon, Jill. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 427McMahon, Ross . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 277, 279McMahon, Siobhan S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 780McMahon, Stephen B.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 451McMenamin, Deirdre. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1McNamara, II, James O. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 662, 663McNeer, Nicole Ali. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 285McPhee, Scott . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 581McPhee, Scott W. J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 160, 778McVey, John H. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 715Mead, Andrew . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 156, 374, 458, 467Mead, Andrew F.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 785Mead, Andy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 454Medin, Jeffrey . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 185, 341Medin, Jeffrey A. . . . . . . . . . . . . . . . . . . . . . . . . 79, 333, 508, 509, 659, 771Medina-Echeverz, Jose. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 810Medina-Jaszek, C. Angelica . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 164Meehan, Anne . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 301Mehta, Jawahar L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 437Mei, Shirley H. J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 907Mei, Z. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 30Mejido, Josef . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 482Melcher, Alan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 481, 606, 607, 610, 653Melero, Ignacio . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 42Mello, Chris . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 674Mendell, Jerry R. . . . . . . . . . . . . . . . . . . . . . . . . . . . 149, 152, 155, 290, 581Mendoza, Janess . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 115, 327Meng, Cuixiang . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 873Meng, Max . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 35Meng, Xin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 192Mercer, Andrew C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 94Meregalli, Mirella . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 460, 464, 795Merlin, Simone. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 134Merling, Randall . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 800Merlini, Luciano . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 258, 666Mermod, Nicolas . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 533Meroni, Germana . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 624Meseck, Marcia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 38, 277EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 167Abstract Author IndexMetzger, Joseph M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 584Metzger, Michael J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 89Meunier, Isabelle . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 169Meyer, Edwin M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 775Meyer, Johann . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 318Meyerholz, David . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 620Mezzadra, Riccardo. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 319Miao, Carol H. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 326, 535, 550Miari, Reem. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 616Michael, Buschmann . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 396Michaud, Annick . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 784Midoux, Patrick . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 324, 395Mikheeva, Galina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 725Mikkelsen, Jacob G. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 695, 726Miliaresis, Jennifer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 164Milinkeviciute, Giedre . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 349Millán, José Luis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 680Miller, A. Dusty. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 89, 623Miller, Ashley M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 380Miller, Darren . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 874Miller, Timothy J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 426, 438Millili, Peter G. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 590Mims, M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 30Mimuro, Jun . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 421, 544Min, Dal-Hee . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 895Min, Seok H. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 61Mincheva-Nilsson, Lucia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 57Mineharu, Yohei . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 26Mineno, Junichi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 652, 678Ming, Xin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 62Mingozzi, Federico . . . . . . . . . . . . . . . . . . . . . . . . . . 8, 43, 66, 546, 548, 614Mingozzi, Federico M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 308Mir, Lluis M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 853Miranda, Paula S. M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 138Miselli, Francesca . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10Miskin, James . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 777Mitchell, James B. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 74, 77Mitchell, Marilyn. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 156, 374, 454, 785Mitrophanous, Kyriacos . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 777Mittal, Plavi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 796Miura, Yoshie. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 263, 899Miyake, Koichi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 410, 510, 680Miyake, Noriko. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 410, 510, 680Miyake, Takashi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 884Miyamoto, Shohei . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 192Miyanohara, Atsushi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 765Miyoshi, Hiroyuki . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 899Mizrak, Arda . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 665, 846Mizuguchi, Hiroyuki . . . . . . . . . . . . . . . . . . . . . . . . . 207, 216, 480, 537, 591Mizukami, Hiroaki . . . . . . . . . . . . . . . . . . . . . . . . . . 207, 421, 428, 544, 554Mizusawa, Hidehiro . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 259Mockaitis, Keithanne. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 353, 356Mockenhaupt, Stefan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 660Modlich, Ute . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 304, 318, 619Mody, Disha A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 222Moen, Robert C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 445, 622Moghimi, Babak. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 146, 763Mohseni, Mahboobeh . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 871Moimas, Silvia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 423, 431Molas, Maria . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 762Moldt, Brian. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 695Monahan, Paul E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 534Monnier, Nilah . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 796Monsma, David . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 487Montazami-Astaneh, Kaweh . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 95Montgomery, Chrystal . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 149Montier, Tristan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 120, 131, 395, 745Montini, Eugenio . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 297, 298, 613Moon, Anne. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 33Moon, Ju Young . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 386Moon, Lawrence. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 451Mooney, Michael A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 235Mooney, Sean . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 353, 356Moore, Nicole M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 589Moot, Robby . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 230Morcinek, Nick . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 681Morcos, Paul A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 49Moreau-Gaudry, François . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 865Moreno, Amira Y. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 161, 452, 752Moreno, Peter J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 272Morgan, R. A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 31Morgan, Richard A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 190, 476, 478Morgello, Susan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 38Morishita, Ryuichi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 884Moritz, Thomas . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 528Morizono, Hiroki. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 416Mornet, Emmanuel . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 120Moroz, Maxim . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 185Morral, Nuria . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 52Morris, Caroline . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 483Morris, John C.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 80, 483, 505Morris, Robert . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 250Morrissey, David . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 398, 848Morrow, Genevieve . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 242Morrow, M. P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 648Morrow, Matthew. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 103Mossalam, Mohanad. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 205Mossoba, Miriam . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 659

168American Society of Gene & Cell TherapyAbstract Author IndexMoulay, Gilles . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 67, 791Moullier, Philippe . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19, 305, 365Mouly, Vincent . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 789Mowa, Betty . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 82Moya, Marta . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 762Mrak, Emanuela. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 315Mrugala, Maciej . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 294Mu, Xiaodong . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 456, 465Muñoz, Nina M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 909Muñoz, Sergio . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 762Mueller, Christian . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 51, 53Mueller, Steffen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 372Muenzer, Joseph . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 328Muether, Nadine. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 636Muir, Lindsey A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 792Mujagic, Edin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 430Mukherjee, Sayandip . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 866Mukhopadhyay, Debabrata. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 606Müller, Oliver J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 241, 432Mullins, Charles . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 639Multhaup, Megan M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 221, 232Munden, Regina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1Muniz Pello, Oscar . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 88, 654Murakami, Akikazu. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 645Muralidharan, Sujatha . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 28Murillas, Rodolfo. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 351Murphy, Michael P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 269, 272, 272Museri, Adi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 719Mussolino, Claudio . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 59, 624Mustafa, Sadaf. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 382Muthumani, K. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 115Muul, Linda . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 296Mykhaylyk, Olga . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 693Myung, Chang-seon . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 896NNa, Chang-Rim . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 731Nace, Rebecca . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 604Nagasaki, Takeshi. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 397Nagasaki, Yukio . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 246, 253Nagata, Keiko . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 236Nagata, Tetsuya . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 56, 565Naik, Rangeetha. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 132Naik, Rangeetha J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 127Naik, Shruthi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 604Naik, Ulhas P.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 590Nair, Smita . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 561Najder, Oliwia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 875Nakagami, Hironori. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 774Nakai, Hiroyuki . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7, 141, 580, 703Nakajima, Satoru . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 678Nakamura, Akinori . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 56, 151, 565Nakamura, Masakuni . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 167Nakamura, Takafumi. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 34, 192, 840Nakamura, Takashi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 401Nakano, Kenji . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 640Nakashima, Hiroshi. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 491Nakashiro, Koh-ichi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 493Nakatsu, Yoshimichi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 97Nakazawa, Yozo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 179, 813Nalam, Madhusudhana R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 404Nalbantoglu, Josephine . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 463Naldini, Luigi . . . . . . . . . . . . . . . . . . . . . . . . . . . 10, 88, 225, 276, 286, 297,. . . . . . . . . . . . . . . 298, 313, 315, 316, 331, 337, 413, 545, 613, 632, 654Nan, Zhenhong. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20Nande, Rounak . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 847Narayanan, Priyadharshini . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 474Narisawa, Sonoko. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 680Narrow, Wade . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 23Narrow, Wade C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 18Nathwani, A. C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 223Nathwani, Amit C.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 668Naundorf, Sonja . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 612Navarro, Claire . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 460Neeley, Andy W. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17Neely, Andrew . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 71Neff, Preston C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 287Negishi, Yoichi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 102Neglia, Simona. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 59Negre, Didier . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 336Negre, Olivier. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 228Nemunaitis, Gregory . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 586Nemunaitis, John . . . . . . . . . . . . . . . 35, 144, 148, 196, 213, 245, 247, 248,. . . 252, 275, 292, 335, 487, 520, 532, 536, 564, 574, 578, 586, 731, 892Neri, Marcella. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 258Neri, Margherita . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 316, 413, 632Neschadim, Anton. . . . . . . . . . . . . . . . . . . . . . . . . . . 185, 333, 508, 509, 771Nettelbeck, Dirk M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 381, 387, 641Neuberg, Patrick. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 883Newman, Nikki . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 873Ng, P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 879Ng, Philip . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 388, 542, 616, 639Nguyen, Andrew T. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 731Ni, Xiahoua . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 251Nichols, Timothy. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 613Nichols, Timothy C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 615Nicholson, Linda J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 716Nickens, Brittani . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 785EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 169Abstract Author IndexNickerson, Michael L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 365Nicklin, Stuart A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 380, 715, 723Nicoletti, Roberto . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 295Nicolson, Sarah . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2Niedernhofer, Laura J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 629, 635Nielsen, Peter E.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 109Nienhuis, Arthur W. . . . . . . . . . . . . . . . . . . . . . . 338, 339, 449, 668, 733, 867Nieva, Jorge. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 33Nikhamin, Yan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 815Nikolskaya, Alena . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 402Nilsson, Berith . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 501, 828Nimesh, Surendra . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 396Nimjee, Shahid M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 667Nishikawa, Makiya . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 670, 862Nishimura, Jun-ichi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 667Nishina, Kazutaka. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 259Nishiyama, Akiyo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 151Nishiyama, Nobuhiro. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 891Nissenson, Allen R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 616Niu, Guoqin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 256Nixon, Alan J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 912No, Daniel . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 772, 794Noble, Misty L.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 326Nokay, Bahar . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 887Nokisalmi, Petri . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 291Nolta, Jan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 281Nordheim, Alfred . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 241Nordling, Diana L.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 280Noske, Nadja . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 92Novelli, Giuseppe . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 908Noviello, Maddalena . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 295Nowrouzi, A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 223Nowrouzi, Ali . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 305, 612Numasaki, Muneo. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 851Nunan, Robert . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 536Nunez-Alonso, Graciela A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 123OObach, Mercè. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 140Obach, Merce. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 762O’Brien, Timothy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 424, 427, 439, 780O’Callaghan, Christopher . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 747Ochiai, Hiroshi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 240Ochs, Hans . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 529Odom, Guy L.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 461, 584O’Donnell, Patricia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 598, 758O’Driscoll, Caitriona. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 254Oehler, Elise A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 599Oette, Sharon M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 445, 622Offord, Chetan P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 208Ofstein, Richard . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 269Ogura, Manabu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 428Oh, Il Ung . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 112Oh, Seeun . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 257Oh, Sung-Min. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 818Ohashi, Kazuo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 141, 419, 903Ohlemiller, Kevin K.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 768Ohlfest, John . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 826Ohmori, Tsukasa. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 421, 544Ohno, Kinji. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 585Oikawa, Tatsuo. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 263Oishi, Motoi. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 246, 253Ojima, Iwao. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 266Okada, Hironori . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 151, 582Okada, Michiyo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 263Okada, Takashi. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 151, 582, 585Okamoto, Sachiko . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 652Okamoto, Shinya . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 851Okamura, Haruki . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 500Okano, Kiichiro. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 445Okano, Teruo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 141, 419, 903Okazaki, Akiyo. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 236Okazawa, Hitoshi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 565Oksanen, Minna . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 193, 538, 658Okun, Alex. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 616Olivares, Jairo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 292Olivares, Simon . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 479Oliveira, Giacomo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 295Olsen, John . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 355Olsen, John C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 881Olson, Erik. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 734Olson, Erik M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 234, 858Olson, Erik R.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 325, 868Olsson-Strömberg, Ulla . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 83, 820Olszewska, Malgorzata . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 32O’Malley, Janis. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 36O’Malley, Thomas. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 758Oneal, Michael J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 80, 505O’Neill, Ann Marie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 379Onishi, Akira . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 428Onodera, Masafumi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 678Orimo, Hideo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 680Orkin, Stuart H. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 338Orlacchio, Aldo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 413Osawa, Kanako . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 236Oshimura, Mitsuo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 236O’Sullivan, G. C.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 194O’Sullivan, Gerald C. . . . . . . . . . . . . . . . . . . . . . . . . . 398, 705, 736, 812, 848

170American Society of Gene & Cell TherapyAbstract Author IndexO’Sullivan Murphy, Bryan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 51, 53Otoi, Takeshige. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 804O’Toole, Daniel. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 427Otsu, Makoto. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 678Otsuka, Makoto . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 749Ou, Wu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 649Owen, Carina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 602Owens, Roland A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 70, 710Ozaki, Kazunari . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 884Ozawa, Keiya. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 207, 421, 428, 544, 554Ozdener, Baris G. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 846Ozelo, Margareth . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 767Ozlem, Senol . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 846PPacholska, Agnieszka . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 212, 512Pacienza, Natalia A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 509, 771Pack, Daniel W. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 119, 595Padegimas, Linas . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 445, 622, 776Padmashali, Roshan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 282, 359Pagliara, D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 178Palanca-Wessels, Maria C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 558Palazón, Asis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 42Palczewski, Krzysztof . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 445Paldor, Mor . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16Palfi, Stephane. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 777Palmer, D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 879Palmer, Donna . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 75, 388, 639, 677Palmer, Donna J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 542Pan, Deng . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 321Pan, Haiying . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 465Pandha, Hardev . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 606Paneda, Astrid . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 485Pang, Jijing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17Pankhong, Panyupa . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 477Papanikolaou, Eleni. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 338Papapetrou, Eirini . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 729Papapetrou, Eirini P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 283Papayannopoulou, Thalia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 137Pappen, Beena O.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 275, 292, 487, 532Pâques, Frédéric . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 87, 462Parato, Kelley. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 33Parfyonova, Elena. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 434Pariétti, Véronique . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 533Paris, Clément . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 883Park, Eugene . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 783Park, Harriet . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 162Park, In-Kyu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 399, 751, 900, 904Park, Jeong-Sook . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 896Park, Keerang . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 722Park, Ryan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 200Park, Sang H. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 687Park, Sang Il . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 128, 406, 754Park, Yeon Hee . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 85Park, Yong Serk . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 128, 406, 754Park, Younjoo. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 722Parker, Alan L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 380, 715Parker, Colleen H.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 907Parker, Ernest T. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 527Parker, Josh. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 852Parkhurst, Maria R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25, 190Parolini, Daniele . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 460, 464, 795Parsons, David . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 874Parsons, David W.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 621Partridge, Terence . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 56Paruzynski, Anna . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 612Pasceri, Peter . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 300Passineau, Michael J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 104Passini, Marco A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 55Pasternak, Alexander. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 797Pastore, Joseph M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 426, 438Pastore, Lucio. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 435Patel, A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 648Patel, Ami . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 169, 724Patel, Manij . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 881Patel, Priti M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 639Patrene, Ken . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 157Pattarini, Lucia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 431Paulk, Nicole K. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 99Pavelko, Kevin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 607Payen, Emmanuel. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 228Peñuelas, Iván . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 42Pearlman, Andrew L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 616Pease, Larry. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 607Peccate, Cécile . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 154Peccatori, Jacopo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 295Pedersen, Alexandra G. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 787Pedro, Helder L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 802Peebles, D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 223Peelman, Luc . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 875Pei-Qi, Liu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 654Pellin, Danilo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 345, 346Peluffo, Hugo. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 451Pelusio, Adina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 33Penaud-Budloo, Magalie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 305, 365Pence, Casey . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 893Peng, Baowei. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 535, 550Peng, Hairong . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 456EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 171Abstract Author IndexPeng, Kah-Whye. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 488Peng, Liaomin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 517Peng, Ling . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 287Penn, Marc S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 426, 438Pepe, Martino . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 423Perabo, Luca . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5Peretz, Mary E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 301, 685Perez, Omar . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 492, 831Perez, Paola . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 761Perini, Giovanni . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 258Perkins, Jeanne . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 314Perna, S.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 178Perna, Serena Kimi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 346Perricaudet, Michel . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 853Perrin, George Q. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 363, 370Perrone, Daniela. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 666Persons, Derek . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 867Persons, Derek A. . . . . . . . . . . . . . . . . . . . . . . . . . . . 338, 339, 524, 525, 861Persson, Jonas . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 180, 264, 843, 849, 863Peshwa, Madhusudan V. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 675Pesonen, Sari. . . . . . . . . . . . . . . . . . 177, 193, 197, 204, 291, 538, 549, 658Pestina, Tamara I . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 525Pestronk, Alan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 152Peters, Brandon . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 356Petersen, Line . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 85Petersen, Line B. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 695Peterson, Kenneth. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 340Petrov, Mihail. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 156, 454, 458, 600, 785Petrov, Mike . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 374Petrs-Silva, Hilda. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 61Petry, Harald . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 249, 255Pfaff, Nils . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 528Pfeifer, Alexander . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 693Phadke, Anagha P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 148, 196, 252, 586Phalon, Connor. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 245Pham, Thu. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 405Phillips, Jana L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 364, 367, 403Phillips, Neil. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 760Phillips, Terry . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 482Piao, Jingshu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 97Piao, Wenying . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 259Piccolo, Pasquale . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 75Pichavant, Christophe . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 462, 790Pichon, Chantal . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 324, 395Picquet, Erwan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 745Pien, Gary . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 43Piersanti, Stefania. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 133Pierson, Tyler Mark . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 235Pietruszka, Marvin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 772Piguet, Françoise . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19Pikkarainen, Jere T.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 209, 669Pilla, James J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 600Pillet, Stephane . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 169Piras, Elena . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 453Piraud, Monique . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19Pisano, F.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 360Pizzitola, Irene . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 845Plank, Christian . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 693Plotkin, Jason. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 184, 655, 911Podetz-Pedersen, Kelly. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 221Podetz-Pedersen, Kelly M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 232Podetz-Petersen, Kelly M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 852Podhajcer, Osvaldo L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 609, 834Podsakoff, Gregory M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8Poeschla, Eric M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 301, 685, 804Polach, Kevin J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 893Polard, Valerie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 110, 113, 853Politi, Letterio S.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 313, 315Ponder, Katherine P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 315, 598Ponnazhagan, Selvarangan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 63, 507, 906Ponomarev, Vladimir . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 184, 185, 333Ponzoni, Maurilio . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 297Pope, M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 648Porada, Chris D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 857Porada, Christopher D.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 551Porcellini, Simona . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 644Postema, Michiel . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 324Potter, Clinton S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 393Pouliot, Frédéric . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 714Poulsen, Hans S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 210, 511Poupiot, Jérôme . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 48Pourfathollah, Ali Akbar . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 871Powell, Kimerly . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 836Powell, Suzanne. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 471Power, Anthony T.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 37Powers, William . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 328Pozmogova, Galina E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 735Pozza, Chiara. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 276Pratico, Elizabeth D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 561Pratt, William D.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 643Premkumar, Muralidhar H. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 677Press, Michael F.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 558Press, Oliver W. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 558Preston, Thomas J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 149Preuss, Meredith A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 36, 503Prieto, Jesús . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 42Prieto, Jesus . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 485, 494, 708, 810Pringle, Ian A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 727

172American Society of Gene & Cell TherapyAbstract Author IndexPristinski, Denis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 589Privman, Eyal. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16Proto, Jonathan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 635Protzer, Ulrike . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 312Provasi, Elena . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 88, 632, 654Pucci, Ferdinando . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 331Pule, Martin. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 845Pulicherla, Nagesh . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 364Pulido, Jose . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 606, 607, 610, 653Puligadda, Uday . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 423Pun, Suzie H.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 730Pupko, Tal . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16Puttaraju, Madaiah . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 422QQanud, Khaled . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 423Qasim, Waseem . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 158, 647Qazi, Aamer M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 250Qi, Feng . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 566Qi, Yanfei . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 518Qiang, Ming. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 211Qiao, Chunping. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6, 420, 683Qiao, Jian . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 195, 495Qin, Bin. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 567Qin, Elizabeth. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 768Qin, Qiuyue . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 164Qin, Rui. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 505Qiu, Guozhen. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 806Qiu, Xiaohong . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 402Qiu, Xingping . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 756Qiujie, Jiang. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 320Qu, Guang. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 69, 673Qu, Jinrong . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 184Quach, Eric . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 782Quattrini, Angelo. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 313, 315Quezada, Valerie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 277, 279Quinn, Thomas. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 674Quintanilla, María Elena. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 766Quintino, Luis. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 350Quiocho, Florante A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 574Quispe, Joel. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 393RRaake, Philip W. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 432Rabinowitz, Joseph . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 600Rabinowitz, Joseph E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 366Rabkin, Samuel D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 608, 829Rachinel, Nicholas. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 336Radd, Katherine . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 422Rader, Daniel J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 412Radrizzani, Marina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 225, 276, 613Radu, Antenata . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 320Radu, Antoneta . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 344, 676Raffeld, M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 31Raggi, Geno. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 457Rah, Dong Kyun . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 516Rahim, A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 697Rainusso, Nino . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 470Rajagopalan, Malolan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 514Rajecki, Maria . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 197, 291Rajendran, Simon . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 398, 812, 848Rajput, Kamal . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 242Raki, Mari . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 197, 291, 549, 658Rakugi, Hiromi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 884Ralph, Scott. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 777Ramesh, Rajagopal . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 243Rameswaran, Rameswari. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 576Ramezani, Ali. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 342, 690Ramirez, Sean M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 125Ramlogan, Charmaine A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 483Ramo, Kasmir . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 448Ramos, C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 30Ramos, Carlos A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 288, 799Ramsay, Tim . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 779Rantanen, Ville. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 204Ranzani, Marco . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 297, 298, 613Rao, Donald D.. . . . . . . . . . . . . . . . . . . . . 245, 247, 248, 252, 532, 564, 892Rao, Mahendra S.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 268Rao, Thapi D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 183Raoul, Sylvie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19Rapp, Brian M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 269, 272Rasmusson, Ida . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 453Rathod, Trushar . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 143Ratiglia, Roberto. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 59Ratner, Nancy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 201Rauschhuber, Christina. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 385Raut, Sanj . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 134Ravin, Suk See De . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 688Rawlings, David J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . 90, 226, 343, 529, 550Ray, William C.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 699Razini, Paola . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 460, 464, 795Razquin, Nerea. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 889Read, Sarah P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 447Readhead, Carol . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 349Rea-Ramsey, Angela . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 893Reay, Daniel P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 457Rebar, Edward . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12Rebello, Tessio . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 41, 646, 803Recchia, Alessandra. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10, 346EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 173Abstract Author IndexRecchia, Fabio A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 423Reddy, Anilkumar K. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 677Reeves, Lilith R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 280Reginato, Silvia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 597Reichenbach, Janine . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 233, 869Reik, Andreas. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 88, 618, 654Rejman, Joanna . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 261, 875Remant, K. C. B.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 129, 755Remaut, Katrien . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 742Remoli, Cristina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 133Remy, Philippe . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 777Ren, Yan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 775Ren, Yong . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 124Restifo, Nichaolas P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 478Restifo, Nicholas P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 190Rex, Tonia S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 441Reyes-del Valle, Jorge . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 168Ricca, Alessandra . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 316Rice, Jennifer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 893Rice, Kevin G.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 117, 594Richard, Emmanuel . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 865Richard, Isabelle . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 48, 793Richards, Amy M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 55, 557Richly, Heike . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 664, 887Riddell, Stainly . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 553Riddell, Stanley R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 618Riley, James. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 341Riley, John P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 190Rimessi, Paola . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 258, 666Riminucci, Mara . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 133Rimler, Avi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 616Rindt, Hansjorg. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 626Rinkoski, Thomas A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 804Ripamonti, Anna. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 225Ripoll, Cynthia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 314, 411Rising, Aaron C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 147Ritsema, Tita . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 249, 255Rival-Gervier, Sylvie. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 300, 691Rivera, Angel A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 834Rivers, Angela E.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 363, 370, 706Rivière, Isabelle . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 184Rivière1, Isabelle . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 911Riviere, Isabelle . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 32, 283Rivkin, Ludmila. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16Riz, Irene . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 690Rizzardi, Gian-Paolo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 644Robbins, Joan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 492, 831Robbins, Paul D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 457, 629, 635Robbins, Paul F. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25, 190Robert-Richard, Elodie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 865Roberts, David D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 731Roberts, Marie S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 22Robinson, Andria R.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 629Roca, Carles. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 140Roccio, M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 360Rockey, William M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 662, 663Rockhill, Jason . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 294Rodgers, John . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 46Rodino-Klapac, Louise R. . . . . . . . . . . . . . . . . . . . . . . . . . . 149, 155, 290, 581Rodrigues, Ana F. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 278Rodriguez, Luis. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 184Rodriguez, Ronald. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 382, 390Rodriguez, Stephen. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 739Roescher, Nienke . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 870Roffler, Steve . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 180, 863Rogers, Faye . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 285Rojas, Juanjo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 291Roland, Herzog W. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 68Rollins, Lisa . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 656Rommelfanger, Diana M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 208Roncarolo, Maria G. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 225Roncarolo, Maria Grazia. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 345, 545Ronen, Keshet . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 228Roode, Luke. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 420Roodman, G. David. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 157Rooney, C.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 30, 178Rooney, Cliona M. . . 28, 29, 179, 288, 293, 472, 473, 656, 672, 799, 813, 816Rooney, Gemma E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 780Roques, Caroline. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 817Rosada, Cecilia. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 695Rosales-Quintero, Xiomara . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 290Roselli, Emanuela . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 319Rosen, Elliot D.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 630Rosenberg, Jonathan B.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 161, 452, 752Rosenberg, S. A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 31Rosenberg, Steven A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25, 190, 476, 478Rossetti, Francesca . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 276Rossi, Claudia. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 319Rossi, John J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 287, 555, 661, 805, 888Rossi, Settimio . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 59Rostomily, Robert . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 294Roujeau, Thomas . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19Rousseau, Joel . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 462, 769Rousseau, Raphael . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 845Rowzee, Anne M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 74, 77, 143Roy, Andre J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 527Roy, Dominic G. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 37Roy, Laura M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 681

174American Society of Gene & Cell TherapyAbstract Author IndexRoy, Soumitra . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 164Roybal, Jessica L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 344, 676Ruan, Li . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 114, 172Ruberte, Jesus . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 762Rubinacci, Alessandro . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 315Rufibach, Laura E.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 796Ruhn, Kelly M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 773Ruiz, Rafaela . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 52Russell, David W. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 234, 858Russell, Stephen J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 195, 203,. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 336,490, 495, 499, 604, 684Russo, Fabio . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 758Ruzo, Albert. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 140Ruzsics, Zsolt . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 385, 712Rwigema, Jean-Claude. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 157, 514Ryals, Renee C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17, 71Ryan, Deborah A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 18Ryan, Martin D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 233Rybalkin, Igor. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 434Ryffel, Bernhard . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 552Ryoo, Soo-Ryoon . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 895Ryu, Byoung . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 529Ryu, Byoung Y.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 90, 226, 343, 909Ryu, Jihoon . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 242, 841SSaadatzadeh, Mohammad R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 272Saadatzadeh, Reza. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 269Sabatelli, Patrizia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 666Sabourin, Kara . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 33Sacchetti, Luciana. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 435Sachar, Einat . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16Sack, Brandon K. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 68, 539Sadadcharam, Mira. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 736Sadelain, Michel. . . . . . . . . . . . . . . . . . . . . . . . . 32, 184, 185, 283, 655, 911Saechao, Chai . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 772, 794Saeki, Koichi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 303, 634Saenz, Dyana T. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 301, 685, 804Safinya, Cyrus R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 393Saga, Kotaro . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 187Sagawa, Hiroaki. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 674Saggio, Isabella . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 133Saha, Sunandan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 813Sahenk, Zarife . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 149, 155, 290, 581Saighal, Sheena . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 625Saini, Massimo. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 337Sainte-Catherine, Vincent . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 110, 113Saito, Nobuhito . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 832Saito, Takahiro . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 419Saito, Takashi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 56, 565Sakata, Yoichi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 421, 544Sakiyama, Yukio . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 678Sakiyama-Elbert, Shelly E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 589Sakuma, Toshie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 688Sakurai, Fuminori . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 537Sakurai, Kumi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 888Sakurai, Yoshihiko . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 903Sakurai, Yu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 246Salavert, Ariana . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 762Salazar, Felix . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 82Salerno, Angela . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 796Sallach, Jessica . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5Sallberg, Matti . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 111, 289Salles, Gilles . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 336Salomon, Daniel R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 408Salomoni, Monica. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 276Salsman, Vita. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 179, 470, 471Saltzman, Daniel . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 852Saltzman, W. Mark. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 285Salvatore, Francesco . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 435Salwa, Slawomir P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 736Samaranayake, Haritha . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 209, 669Sampath, Alapakkam P.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 21Sampath, Prakash . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 182Sampedro, Ana . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 42Samulski, Jade. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 581Samulski, Jade J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 160Samulski, R. Jude. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2, 60, 160, 366, 581Sanchez, Ceidy. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 28, 672Sanchez, Massimo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 908Sanchez-Bonilla, Marilyn . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 330Sanchez-Salazar, Jorge . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 517Sanders, Niek N. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 875Sandhu, Arbans . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 625Sands, Mark S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 22, 768Sanges, Daniela . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 624Sangiuolo, Federica. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 908Sankaran, Vijay G. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 338Sanmiguel, Julio C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 759Sano, Akiko. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 236Santiago, Virgínia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 570Santilli, Giorgia. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 866Santistevan, Nicholas . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 355Sanvito, Francesca . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 297, 315Sapag, Amalia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 766Sardesai, N. Y. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 648Sardesai, Niranjan Y. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 103, 115, 327, 477Sardi, S. P.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 55EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 175Abstract Author IndexSargent, R. G. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 913Sarkar, Devanand . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 503Sarkar, Rita . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 134Sarkaria, Jann N. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 499Sarkioja, Merja. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 549Sarwari, Roya . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 617Sasaki, Erika . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 899Sather, Blythe . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 529Sather, Blythe D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 226, 343Sato, Makoto. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 714, 850Sato, Takeya . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 333, 508Sato, Yusuke . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 894Sauthoff, Harald . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 713Savarala, Sushma. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 757Savilahti, Harri . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13Savoldo, B. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 30, 178Savoldo, Barbara . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 288, 472Savontaus, Eriika . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 145Savontaus, Mikko. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 145Sawall, Stefanie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 833Sawari, Roya . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 530Saxena, Romil . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 52Saydam, Okay . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 665, 846Sazani, Peter . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 56Scaife, Matthew D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 509, 771Scallan, Martina F. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 705Scaramuzza, Samantha. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 225Schöler, Hans. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 284Schürmann, Nina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 660, 886Schaffer, David. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 299Schaffer, David V. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8, 442, 802, 805Schaller, Torsten . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 647Schambach, Axel . . . . . . . . . . . . . . . . . . . 284, 302, 304, 318, 528, 619, 869Scharenberg, Andrew M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 90, 909Schatzberg, Scott . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 467Scherman, Daniel . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 67, 400, 791Scheulen, Max E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 664, 887Scheurer, Michael . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 471Schiedlmeier, Bernhard . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 619Schindler, John. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 288Schira, Giulia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 337Schlachterman, Alexander . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 308Schlegel, Philipp . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 432Schleifman, Erica B. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 285Schlesinger, Pnina. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 719Schlesinger, Sarah J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 162Schmidt, Claudia. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 162Schmidt, M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 223Schmidt, Manfred . . . . . . . . . . . 138, 286, 297, 298, 305, 345, 346, 347, 612Schmidt, Manuel . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 189, 664, 822, 887Schneider, Kellie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 36Schroeder, Mark A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 499Schroeder, Timm. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 284Schroff, Matthias . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 189, 822Schuldt, Nathan J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 651Schuldt, Nathaniel J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 638Scott, Jeannine. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 638Scott, Stephanie. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 487Scotton, Chiara. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 258Scruggs, Brittni. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 314, 411Seethammagari, Mamatha. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 474Seger, Reinhard A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 233, 869Segura, Maria Mercedes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 573Seidler, Daniela G. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 198Seinstra, Beatrijs. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 815Selby, Peter . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 606, 653Semaan, Assaad. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 250Semenova, Katerina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 158Senac, Julien S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 701Sena-Esteves, Miguel. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 57, 450Sengupta, Sadhak . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 718Senol, Ozlem . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 665Senyukov, Vladimir . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 479Senzer, Neil . . . . . . . . . . . . . . . . . . 148, 196, 213, 245, 247, 248, 252, 292,. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 335, 487, 532, 536, 564, 586, 892Seo, Hae-Hyun . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 384Seregin, Sergey S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 638, 651Sergi Sergi, Lucia . . . . . . . . . . . . . . . . . . . . . . . . . . . 297, 313, 316, 545, 613Serguei, B. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 26Servais, Elliot . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 184Serve, Kinta. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 330Sesenoglu-Laird, Ozge . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 445, 622Sest, Maike . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 239Sethupathy, Praveen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 54Sevin, Caroline . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19Seward, Shelly M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 250Seymour, Len. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 602Seymour, Len W. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 732Shabashvili, Arseniy E.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 518, 854Shafer, Jessica A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 473Shaffer, Donald . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 471Shah, Ami . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 296Shah, Rachel . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 308Shaheen, Sharif M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 401Shahrokhi, Somayeh. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 871Shammas, Masood A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 250Shan, Changguang . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 432Shanker, Manish. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 243

176American Society of Gene & Cell TherapyAbstract Author IndexShao, Hongwei. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 603Sharif, Faisal . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 439Sharifi, Zohre . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 871Sharma, Nynne . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 726Shashkova, Elena V. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 489Shaw, Georgina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 270Shaw, Kit L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 296Shayakhmetov, Dmitry M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 541Shchelochkov, Oleg A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 677Shea, Lonnie D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 121, 764, 770Sheehan, Andrea M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 293Shen, Hui . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 709Shen, Shen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 62Shen, Xuefei . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 103, 115, 327, 477Shen, Ying. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 713Shenker, Larissa . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 185Shenker, Larrisa . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 184Sher, Yu-Ping . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 844Shevchenko, Eugeniy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 434Shevelev, Alexander . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 434Shi, Qin. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 756Shida, Hisatoshi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 34, 840Shihabuddin, Lamya S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 55, 557Shiku, Hiroshi. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 652Shilling, Christopher . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 581Shilling, Christopher J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 155, 290Shim, Kyu-Woong . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 818Shima, Midori . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 903Shimabukuro-Vornhagen, Alexander. . . . . . . . . . . . . . . . . . . . . . . . . . . 664, 887Shimada, Hideaki . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 851Shimada, Takashi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 410, 510, 680Shimamura, Munehisa. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 774Shimizu, Hirofumi. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 419Shimizu, Hiroyuki . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 192Shimizu, Keiji. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 513Shimizu, Masaki. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 227Shimoda, Shinya . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 899Shin, Jin-Hong . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 151, 587, 601Shin, Qiaoyun . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 731Shin, Seong-Phil . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 384Shin, Young Eun . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 128Shirakawa, Toshiro . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 167Shirazi, Rahau S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 393Shirley, Shawna . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 823Shi-Suo, Du . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 73Shitara, Shingo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 236Shivakumar, Rama . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 675Shontz, Kimberly . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 149Shoshani, Ehud . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 616Shovlin, Lindsay . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 41Shu, Yuelong . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 172Shuai, Lifang . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 171, 807, 808Shui, Hongshu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 620Shukla, Ravi S.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 567Shukla, Vasundhara . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 132Shultz, Leonard D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 285Siddiq, Ishita . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 783Sidow, Arend . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14Siegal, Gene P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 36Silbergeld, Daniel L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 294Siler, Ulrich . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 233, 869Silka, Kimberly A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 21Silva, Ana Carina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 579Silva, Flavia H.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 440Simão, Daniel . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 579Simioni, Paolo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 615Simonelli, Francesca . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 59Simonsson, Bengt. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 83, 820Simula, Pekka . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 177Singh, Anand Kamal . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 132Singh, Harjeet . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 479Singh, Rakesh K. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 593Sirrka, Liisa . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 538Sitaraman, Varsha . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 372Sivakumar, Kumaraswamy. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 155Skarica, Mario . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 859Skiena, Steven. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 372Skinner, Amy M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 692Skog, Johan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 57, 846Skripchenko, Yelena . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 274Skvorak, K. J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 139Slawin, Kevin M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 474Sleep, Susan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 668Sleeper, Meg M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 433, 598Sleer, Leanne. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 536Sloan, Jennifer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 135Slobodkin, Gregory . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 893Sloniecka, Marta . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 204Slovin, Susan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 184Smerdou, Cristian . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 42Smith, Bruce F.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 379, 587Smith, Carol. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 162Smith, Edvard C. I. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 556Smith, Jeffrey S.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 542Smith, Laura J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3Smogorzewska, Monika . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 296Snead, Nicholas M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 888Snyder, Brooke R.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 778, 782EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 177Abstract Author IndexSnyder, Jenni A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 310Snyder, Richard O. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 305, 365Soballe, Kjeld. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 787Sobczak, Krzysztof . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 49Sobolewki, Peter . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 425Soden, Declan M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 736Soedling, Helen M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 716Sokolic, Robert. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 296Soldati, Corrado . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 295Söllü, Cem. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 95Soma, Emilienne . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 110, 113Somanathan, Suryanarayan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 543Somia, Nikunj V.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 221, 232Sommerfield, Marla . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 488Somoto, Vivian. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 440Sondhi, Dolan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19Song, Cunxian . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 753Song, Hyung Geun . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 406Song, Jae J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 257Song, Min-sun . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 888Song, Shuxian . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 326Song, Sihong . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 375, 775Song, Xiao-Tong . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 656Song, Xiatong . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 816Sørensen, Charlotte Brandt. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 91Sorenson, Brent . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 852Sorrentino, Brian P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 222, 354, 860, 861Sosale, Nisha. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 357Sousa, Marcos F. Q. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 579Soustek, Meghan S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 596Sowers, A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 74Sowers, Anastasia. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 77Spanggaard, Iben . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 106Sparks, Jeff . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 893Spence, Alexander . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 294Spencer, David M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 288, 474Spencer, H. Trent . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 527, 814Spencer, H. Trent B. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 230Spencer, Jacqueline F. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 489Spitalieri, Paola . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 908Spratt, S. Kaye. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 783, 798Sprengel, Rolf . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 241Spriggs, David R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 183Springer, Joseph . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 44, 224, 373Springfeld, Christoph . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 833Spyridonidis, Alexandros . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 340, 729Squillace, Karen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 633Sreenath Nagamani, Sandesh C.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 677Srinivasan, Rahul . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 781Srivastava, Arun . . . . . . . . . . . . . 61, 363, 369, 370, 540, 587, 700, 704, 706Stabenow, Dirk. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 312Stalvey, Michael . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 444Stamatoyannopoulos, George. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 137Stanek, Lisa M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 55, 557Staunstrup, Nicklas H. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 726Staunstrup, Nicklas Heine . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 91Stavrou, Eleana . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 340, 729Stayton, Patrick S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 558Stedman, Hansell . . . . . . . . . . . . . . . . . . . . . . . 156, 374, 454, 458, 467, 785Stedman, Hansell H. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 600Steel, Jason C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 483Steet, Richard . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 759Stefanska, Anna . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 159Stefanski, Jolanta . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 32, 184Steffes, Christopher. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 250Stein, David. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 646Stemmer-Rachamimov, Anat O.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 665Stenderup, Karin. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 695Stephenson, Joe. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 33, 35Sterling, Brigid V. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 226Stern, Baruch S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 616Stetler-Stevenson, M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 31Stevenson, Mark . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 732Stewart, Duncan J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 907Stirling, Brigid . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 529Stirling, Brigid V.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 343Stocca, Alessia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 427Stockdale, Katie R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 662, 663Stoddard, Barry L.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 89Stok, Merel . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 315Stone, Brandon . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 514Stone, Daniel . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8Storb, Rainer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 553, 623Straathof, Karin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 288Strauss, Robert. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 265Strom, S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 139Stroup, Katie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 689Studer, Lorenz . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 283Su, Leonard . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 454Su, Qin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 58, 362, 450, 671Suda, Takeshi. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 322Sudol, Kelly L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 18Sudres, Muriel . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 552Suehara, Tetsuya . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 670Suehiro, Youko. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 263Suel-Petat, Laurence . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 793Suga, Tomohiro . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 468Sugiyama, Daisuke . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 263

178American Society of Gene & Cell TherapyAbstract Author IndexSugiyama, O.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 687Sukegawa, Jun. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 508Sule, Gautam. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 46Sullenger, Bruce A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 561, 667Sullivan, Millicent O. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 590Sullivan, Timothy A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 441Sumaroka, Marina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 600Sumimoto, Hidetoshi. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 480Sumiyoshi, Teiko . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 522Sumner-Jones, Stephanie G.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 880Sumners, Colin. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 518, 854Sun, Baodong . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 47, 136Sun, Bo K.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 257Sun, Lan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 433Sun, Q. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 139Sun, Samuel S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 326Sun, Wenchao . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 746Sun, Xingshen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 620Sundaram, Ramakrishnan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 852Surace, Enrico M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 59, 624, 702Surosky, Richard. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 783Sürth, Julia D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 304Suwanmanee, Thipparat . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 534Suzuki, Kei . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 184Suzuki, Masataka. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 46, 224, 309, 642Suzuki, Ryo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 102Suzuki, Ryosuke. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 748Suzuki, Takayuki . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 537Suzuki, Toru. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 216Suzuki, Yumi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 585Swaim, William D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 77Swain, JaBaris D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 600Swaney, William P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 280Swanson, Debra . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20, 221Swanson, Debra L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 232Sweeney, Colin L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 220Sweeney, H. Lee . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 433, 625Swiderski, Piotr . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 287Symens, Nathalie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 742Sysol, Justin R.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 135Sze, Daniel Y. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 214Szpirer, Cedric Y.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 740TTabata, Toshiaki . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 303, 634Tada, Yuji . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 851Tadlock, Matthew V. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 408Tafuro, Sabrina. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 140Tagalakis, Aristides . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 747Tagawa, Masatoshi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 851Tahan, V.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 139Tahara, Hideaki . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 34, 840Tai, April . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 689Tai, Ching-Lung. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 583Tai, Khalid . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 350Tak, Paul P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 231, 548, 870Tak, Paul-Peter . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 66Takahashi, Atsushi. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 263, 899Takahashi, Masamichi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 832Takahashi, Rei . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 862Takahashi, Yoko E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 102Takahashi, Yuki . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 670, 862Takakura, Yoshinobu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 670, 862Takeda, Kiyoshi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 480Takeda, Shin’ichi . . . . . . . . . . . . . . . . . . . . . . . . . . . . 56, 151, 565, 582, 585Takeya, Yasushi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 884Takiya, Christina M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 440Talbot, Gill . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 158Tamai, Katsuto . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 187, 628Tampier, Lutske . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 766Tamura, Masakazu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 513Tan, L. G.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 697Tan, M. H. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 697Tan, Shuping . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 376Tan, Wenjie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 78, 114, 172, 238Tang, Qiushi. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 51, 53Tang, Ruhang. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 420Tang, Terence. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 218Tang, Yaoping . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 677Tang, Ying . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 635Tang, Yucheng . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 85Tangney, Mark . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 398, 705, 812, 848Tanguay, Robert M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 242Tani, Kenzaburo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 192, 263, 899Tani, Tomomi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 591Tannous, Bakhos A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 57Tansey, Malu G. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 773Tapscott, Stephen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 553Tapscott, Stephen J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 623Tarantal, Alice F. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 522Tarragona, Tony . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 162Tateno, Chise . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 141Tatsumi, Kohei . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 141, 903Tatsuzawa, Osamu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 678Taube, Ran . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 645Tavernier, Geertrui. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 261Tayler, Matthew A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 191Taylor, Catherine A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 218EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 179Abstract Author IndexTaylor, Clare. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 32, 911Taylor, Justin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 659Telen, Marilyn J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 667Tellez, Joe . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 857Tellez, Joseph. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 551Temme, Achim . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 833Templeton, Nancy S. . . . . . . . . . . . . . . . . . . . . . . . . . 247, 564, 574, 586, 731ten Bloemendaal, Lysbeth . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 138Tenenbaum, Lilianne . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 708Tennant, Peter . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 880Terada, Nobuyuki . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 500Terakura, Seitaro . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 618Terao, Shuji . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 216Tesarfreund, Matthew . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 475Testa, Francesco . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 59Teter, Mary A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 847Tey, Siok K. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 288Thaci, Bart. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 835Thakur, Garima. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 132Thatava, Tayaramma. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 633Theobald, Narda . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 354Thibault, Marc . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 396Thibodeau-Beganny, Stacey . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 95Thiel, Kristina W.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 662, 663Thiel, William H.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 662, 663Thomas, Darby L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 377, 571Thompson, Colin J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 254Thompson, Jill . . . . . . . . . . . . . . . . . 175, 481, 496, 606, 607, 610, 611, 653Thompson, John E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 218Thompson, Patrick . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 767Thornton, Charles A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 49Thrasher, Adrian . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 158, 617, 647Thrasher, Adrian J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 866, 229Throm, Robert E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 354, 861Thung, Swan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 38Thurlings, Rogier. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 548Tian, Jie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 542Tian, Jun . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 358Tian, Runxia. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 603Tian, Wenhong. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 238, 376Tiboni, Francesca . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 319, 523Tiemann, Katrin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 555Tikoo, Suresk K. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 724Tilstra, Jeremy S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 629, 635Timares, Laura . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 379Tisdale, John F.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 352Tkachuk, Vsevolod A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 434Tobita, Kimimasa . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 703Todo, Tomoki . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 832, 839Todorow, Carlyn . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 344, 676Toietta, Gabriele . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 898Toita, Nariaki . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 678Tojyo, Masahiko . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 825Tol, Nikki. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 40, 502Toma, Shoko . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 826Tomasulo, Catherine . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 600Tomizuka, Kazuma . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 236Tong, Alex W.. . . . . . . . . . . . . . . . . . 148, 196, 245, 248, 252, 292, 335, 564Tonne, Jason M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 599Torbett, Bruce E.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 348, 650Torrente, Yvan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 460, 464, 795Toscano, Miguel G. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 859Toth, Karoly . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 489, 837Totterman, Thomas H. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 176Toumadje, Araz . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 905Toutouna, Louiza . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 729Towers, Greg . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 647Townsend, Dewayne . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 584Toyota, Hiroyasu. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 862Tran, Kaylie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 64Tran, Kaylie N. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 169Tran, Rosa . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 361Trani, Marianna . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 430Transfiguracion, Julia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 361Tremblay, Jacques P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 462, 769, 784, 790Trevino, Isaac . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 773Tripic, Tamara. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 473, 799Trobridge, Grant D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 909Trochon-Joseph, Veronique . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 110, 113, 853Trueck, Christina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 693Trujillo, Miguel A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 80, 505Truong, Lynn . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 798Trygg, Cynthia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 314Tsai, Richard K.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 357Tschaika, Marina. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 189, 664, 822, 887Tschernia, Nick . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 551Tschulena, Ulrich. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 339Tsokolaeva, Zoya . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 434Tsokos, Maria. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 135Tsukahara, Tomonori . . . . . . . . . . . . . . . . . . . . . . . . . 207, 421, 428, 544, 554Tsuno, Takaya . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 482Tsuzuki, Teruhisa . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 97Tuppurainen, Venla . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 212Turchetto, Lucia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 276Turnis, Meghan E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 816Turrell, Susan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 215Tuschong, Laura M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 234, 524, 858Tuunanen, Pasi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 159

180American Society of Gene & Cell TherapyAbstract Author IndexTuve, Sebastian . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 180Tyr, Elena. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 445Tyr, Olena . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 622Tysome, James. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 605Tzekov, Radouil . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 444UUchibori, Ryosuke . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 207Uchida, Hiroaki. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 640Uchida, Naoya . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 352Uchida, Yuji . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 468Uchil, Pradeep . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 285Uchino, Makoto . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 468, 788Uchio, Katsuhisa. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 468Uchiyama, Masayuki. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 97Uchiyama, Toru . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 227Ueda, Yasuji. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 824Uesugi, Motonari . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 670Uhrig, Silke . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5Uitto, Jouni . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 320Ukawa, Masami . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 743Ulasov, Ilya V. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 191, 718, 835Ulkoski, David . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 893Ulrich-Vinther, Michael . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 787Uludag, Hasan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 129, 562, 568, 755Umino, Yumiko . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17Ungari, Silvia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 313, 316Ungaro, Daniela . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 313, 315Ungerechts, Guy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 833United Dystrophinopathy Project Consortium . . . . . . . . . . . . . . . . . . . . . . . . . 152Uno, Yoshitaka. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 259Unzu, Carmen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 42Urabe, Masashi . . . . . . . . . . . . . . . . . . . . . . . . . . . . 207, 421, 428, 544, 554Urasawa, Nobuyuki. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 56Urata, Yasuo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 192Urban, Jon. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 402Urban, Nicole . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 265Urness, Myra . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 325Urtti, Arto O. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 750Usachenko, Yelena . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 815Utoh, Rie. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 141, 419VVähäkangas, Elisa. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 765Völkel, Christine . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 284Vago, Luca. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 295Vaha-Koskela, Markus . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 39Valdmanis, Paul N. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 54Valero, Valderez B. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 440Vallanti, Giuliana. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 225, 276, 613Valles-Ayoub, Yadira . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 772, 794Valley, Robert. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 328Valli, Emanuele . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 258Valouev, Anton . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14van Beusechem, Victor W. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 40, 502van de Loo, Fons A. J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 559, 627van den Berg, Fiona . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 563van den Berg, Wim B. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 559, 627van der Loo, Johannes C. M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 280van der Meulen-Muileman, Ida . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 40van Deutekom, Judith C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 153van Deventer, Sander . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 255Van Dusen, Nate. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 353van Logtenstein, Richard . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 249van Ommen, Gert-Jan B. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 153Van Pijkeren, Jan P.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 398Van Poucke, Mario . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 875van Praag, Henriette . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 355van Rensburg, Ruan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 93van Rooijen, Nico . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 380, 723van Sinderen, Douwe . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 848van Til, Niek P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 530, 617Van Vliet, Kim . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 58, 65Van Zwieten, Ruthger . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 533Vandenberghe, Luk H. . . . . . . . . . . . . . . . . . . . . . . . . . . . 1, 65, 368, 412, 759Vanier, Marie-Thérèse . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19Vanrell, Lucia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 485, 708Varghese, Steve . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 773Varki, Ajit . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 546Varney, Michelle L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 593Vasan, Sandhya . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 162Vasseur, Virginie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 552Vaughan, Andrew E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 623Vaughan, Erin E.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 424, 588Veenbergen, Sharon . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 559Velazquez, Omaida C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 603Venditti, Charles P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 135, 679, 701Vera, Juan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 469Vera, Juan F. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 28, 29, 672, 799Verhoeyen, Els . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 336Vermeij, Eline A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 627Vermeulen, Christie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 40, 502Verstegen, Monique M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 617Vervoordeldonk, Margriet J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 66, 231, 548Vetrini, Franesco. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 388Viale, Diego L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 609, 834Viapiano, Mariano . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 199Viarengo, G. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 360EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 181Abstract Author IndexVickers, Selwyn M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 391, 497Viita, Helena . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 512Vile, Richard. . . . . . . . . . . . . . . . . . . 175, 481, 496, 606, 607, 610, 611, 653Vile, Richard G.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 208Villa, Anna. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 225, 617Villani, Edoardo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 59Vincent, Justin M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 572, 575, 738Vinogradov, Serguei V.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 593Vinti, Maria . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 777Viola, Francesco . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 59Viollet, Laurence. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 155Virk, Mandeep S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 687Virtanen, Siru. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 145Visel, Meike. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 442Visigalli, Ilaria . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 313, 315, 316Visser, Trudi P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 530, 617Vitetta, Ellen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 288Vlasik, Tatyana. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 434Vleck, Jan P.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 856Vo, Thuy D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 98Vogel, Peter. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 525Vogler, Carole. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 768Voigtlander, Richard . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 385Voit, Thomas . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 154Volpin, Monica . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 298Volz, Baerbel . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 189, 822von Bergwelt-Baildon, Michael S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 664, 887von Kalle, Christof. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 286, 305Von Kalle, Christof. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 345von Kalle, Christof. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 347, 612, 833von Messling, Veronika . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 169VonKalle, Christof . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 297, 298Vorhies, John . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 564Voss, Tiffini . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 779Vosters, Jelle L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 870Voutetakis, Antonis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 143Vrettou, Christina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 880WWada, Jun . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 167Waddington, S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 223, 697Wade-Martins, Richard. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 602, 732Wadhwa, Renu. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 242, 841Wagemaker, Gerard . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 530, 617Waisbren, Emily . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 237Waite, Katherine. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 39Wakimoto, Hiroaki . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 608, 829Walker, Christopher M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 149, 155,. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 290, 581Walker, William . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 685Wall, Cheryl . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 155Wallraven, Gladice . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 292, 520Wan, Wen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 36Wancewicz, Edward . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 557Wanders, Alkwin. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 176Wandless, Tom J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 350Wang, Adele Y.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 79Wang, Anqi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 171, 807, 808, 854Wang, Bing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 457, 635Wang, Cathy X. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 348Wang, Danher . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 504, 643Wang, Gang. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 238, 376Wang, Gary P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13Wang, Hao . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 453Wang, Hong . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 515Wang, Hongjie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 415, 657, 843Wang, Hongxun . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 195, 495Wang, Huan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 416Wang, Hui . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 200Wang, James . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 341Wang, Jenny . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 39Wang, Jianbin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11, 801Wang, Jun. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 422Wang, Li . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 433Wang, Lijun . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 377, 571Wang, Lili . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 45, 416Wang, Minghui. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 36, 503, 834Wang, Mingxing. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 890Wang, Nanya. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 510Wang, Pengju . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 605Wang, Pin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 686, 689Wang, Pin-Yi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 498Wang, Qiang . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 58Wang, Shengdian . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 605Wang, Wei . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 347Wang, Weijun . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 200Wang, Wen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 172Wang, Wenjing. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 171, 806, 808Wang, Xinzhong. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 517Wang, Xiuyan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 32, 184, 911Wang, Yaohe . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 605Wang, Yifeng. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 186Wang, Yong. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 753Wang, Yuan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 266Wang, Yue. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 694Wang, Yuhua . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 329Wang, Yun. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 709Wang, Zejing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 553, 623

182American Society of Gene & Cell TherapyAbstract Author IndexWang, Zhaohui. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 245, 247, 532, 564, 892Wang, Zhongya . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 306, 681, 682Wanisch, Klaus. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 451Ward, Charles. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 372Wargo, Jennifer A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 190Warlich, Eva. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 284Washington, Kareem N.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 352Watanabe, Yoshihiko. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 862Watcharanurak, Kanitta . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 862Watts, Ashlee A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 912Watts, Korashon L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 631Watts, Victoria . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 155Weaver, Donald W. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 250Webb, Craig. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 487Weber, Christian . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 305Weber, Christophe. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 432Weihrauch, Martin R.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 664, 887Weiland, Ola . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 289Weinberg, Marc S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 563Weiner, D. B. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 648Weiner, David B.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 103, 115, 327, 477Weinfeld, Michael. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 568Weiss, Robert B.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 152Wenzel, Daniela . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 693Werfel, Stanislas M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 241Wesa, Amy K. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 271Westenberg, Marcel . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 716Wheeler, Thurman M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 49White, Edward A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 394Whitehouse, Adrian. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 215Whitley, Chester B. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20Wibowo, Mia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 181Wicke, Daniel C.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 318Wielgosz, Matthew M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 733Wilber, Andrew. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 338, 339Wilen, Craig B.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 801Wilkinson, Leslie. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 893Willenbring, Holger . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 910Willerth, Stephanie M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 802Williams, Bradley A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 796Williams, James A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 166, 572, 575, 738Williams, Jon P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 201Williams, Kyha . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 142Willmon, Candice L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 611Wilson, Aisha . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 412Wilson, Carolyn . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 649Wilson, James M. . . . . . . . . . . . 1, 45, 65, 164, 368, 412, 416, 543, 625, 759Wilson, John . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 672Wilson, Kyle A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 273Wilson, Matthew H. . . . . . . . . . . . . . . . . . . . . . . . . . . . 12, 15, 179, 472, 813Wilson, W. H.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 31Wilton, Steve D.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 789Wimley, William . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 314, 411Wimmer, Eckard . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 372Windebank, Anthony J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 780Winnik, Francoise M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 756Winterton, Matthew . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 659Wipf, Peter . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 157Wirth, Thomas . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 212, 512Wittig, Burghardt . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 189, 664, 822, 887Witting, Scott R.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 52, 675Wohlgensinger, Vital . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 233, 869Wolchok, Jedd D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 817Wold, William . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 196, 496Wold, William S. M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 489, 837Wolf, Daniel A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20Wolf, Gernot . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 726Wolfe, John H. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 317, 901Wolff, Jon . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 160Wolff, Thomas . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 430, 597Wong, Fay E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 645Wong, Kamehameha K.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3Wonganan, Piyanuch. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 435Wongsrikeao, Pimprapar . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 804Wongthida, Phonphimon . . . . . . . . . . . . . . . . . . . . . . . . . . 175, 481, 607, 610Woo, Savio . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 38, 277Wood, Josh . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 857Woodward, Josha A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 692Worgall, Stefan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 161, 452, 752Worgall, Stefen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 163Worley, Kim C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 574Wozniak, David F.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 768Wright, J. F. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 308Wright, J. Fraser. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 614Writer, Michele J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 394Wu, Bo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 890Wu, Chih-Hsien. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 882Wu, Hao . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 84Wu, Lily. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 714, 850Wu, Ping . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 390Wu, Robert A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 864Wu, Shourong . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 891Wu, Susan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 598Wu, Xiaobing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 78, 238, 376Wu, Yihan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 839Wunder, Stephanie L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 757Wurdinger, Thomas . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 665EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 183Abstract Author IndexXXagorari, Angeliki . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 137Xia, Danny. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 98Xia, Xuexing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 737Xiao, Bin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 683Xiao, Ping-Jie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 60Xiao, Ru . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1, 65, 368Xiao, Weidong . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 310Xiao, Xiao . . . . . . . . . . . . . . . . . . . . . . . . . . 6, 160, 420, 457, 581, 683, 790Xiao, Yan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 332Xie, Boxun. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 38Xie, Jun. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 58, 362, 450, 671Xie, Qing. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 58, 362, 450Xiong, Weidong . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 26Xiong, Zhengming. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 826Xiuying, Liu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 663Xu, Acong . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 467Xu, Xiabin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 423Xu, Yaqin. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 163Xu, Zhili . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 542Xu, Zuoshang. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 450Xue, Shao-An . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 349YYáñez-Muñoz, Rafael J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 451Yadav, Swati . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 160Yagi, Hiroya. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 421, 544, 554Yagiz, Kader . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 26, 181, 475Yaguchi, Tomoko . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 841Yamada, Masafumi. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 678Yamada, Meiko . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 192Yamada, Yuma. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 748Yamaguchi, Saori . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 899Yamaguchi, Tomoko . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 537Yamamoto, Masato. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 80, 391, 497Yamamoto, Motoko . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 410Yamamoto, Sakura . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 167Yamamoto, Seiko . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 680Yamaoka, Norie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 500Yamasaki, Satoshi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 391Yamashita, Atsushi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 401Yamato, Masayuki . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 419Yamazaki, Takehiko . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 187, 628Yamazoe, Sayumi. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 670Yamoshita, Satoshi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 468Yan, J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 648Yan, Jian . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 115, 327, 477Yan, Ziying . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4, 620Yanagisawa, Teruyuki . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 508Yang, Bin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 450Yang, James C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25Yang, Lin. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6Yang, Ningning. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 741Yang, Shan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 851Yang, Sherry W. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 507Yang, Shicheng . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 476, 478Yang, Wendy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 557Yang, Xiao. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 69, 885Yang, Xiao Yi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 47Yang, Y. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 913Yang, Ye . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 130Yanik, Tulin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 143Yannaki, Evangelia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 137Yao, Feng . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 237Yaouanc, Jean Jacques . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 745Yardeni, Tal . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 144Yarnall, Charles . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 156Yasukawa, Masaki . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 652Yasumura, Eduardo G. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 440Yawata, Toshio. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 513Ye, Bin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 218Ye, Delia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 165Ye, Guo-jie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 377, 571Ye, L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 913Ye, Peiqing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 535, 550Ye, Yihong. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 876Yeagy, Brian A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 408Yeh, Raymond . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 32, 815Yehling, Eric. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 23Yen, Benjamin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 535Yen, Tzu-Chen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 583Yeung, Jonathan C.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 872Yi, Yaling. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 620Yin, Xiao . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 78, 114Yip, Ping . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 451Ylä-Herttuala, Seppo . . . . . . . . . . . . . . . . . . . . . 159, 209, 212, 512, 669, 765Ylaya, Kris . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 659Yockman, James W. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 86, 126Yokota, Takanori. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 259Yokota, Toshifumi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 56, 565Yonemitsu, Yoshikazu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 824Yong, Liu. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 819Yongabi, Felicitas . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 159Yoo, Ji Young . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 198, 811, 841Yoo, Ji-Young . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 836Yoon, A-Rum . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 84, 198, 720Yoon, DoHeum. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 260Yoon, Sang Soon . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 406

184American Society of Gene & Cell TherapyAbstract Author IndexYoshida, Kie. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 259Yoshihara, Chieko . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 825Yoshikawa, Hiroyuki . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 554Yoshimura, Toshiro . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 585Yoshizato, Katsutoshi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 141You, Chang Xuan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 819You, Chia Chin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 173Younes, Anas . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 473Yu, Di . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 501, 828Yu, Gang . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 105Yu, Hongwei . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 412, 759Yu, Jimin. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 411Yu, Julie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 299Yu, Seungshin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 818Yu, William . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 713Yu, Yang . . . . . . . . . . . . . . . . . . . . . . . . . 248, 275, 292, 335, 487, 532, 564Yu, Zhiya. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 190, 478Yuan, C. M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 31Yuan, Jinyun . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 650Yuan, Zhenhua. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6, 683Yue, Yongping . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 150, 466, 587, 601Yuen, Carrie. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 809Yu-Feng, Lin. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 288Yugeta, Naoko . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 582Yui, Nobuhiko . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 401Yumul, Roma . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 180, 264, 843, 849, 863Yun, Chae-Ok . . . . . . . . . . . . 84, 86, 188, 198, 202, 242, 516, 720, 811, 841Yun-shan, Tan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 73Yurek, David M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 776Yusa, Kosuke . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15Yvon, Eric . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 288ZZacchigna, Serena. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 423, 431Zahid, Maliha. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7Zaitseva, Marina A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 735Zamore, Phillip D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 362Zaoui, Karim . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 305Zavaljevski, Maja . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 730Zeigerman, Haim . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 719Zenadi, Rahima . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 667Zeng, Jinfeng . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 807Zeng, Lepeng . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 402Zeng, Yué . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 463Zeng, Zhao-Chong. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 211Zentilin, Lorena . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 311, 423, 431Zerah, Michel. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19Zerfas, Patricia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 135Zervou, Fani. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 137Zhan, Jun . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 733Zhang, Dazhi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 819Zhang, Fang . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 617Zhang, Feijie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 306Zhang, Guisheng. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 322Zhang, Hongwei . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 362, 450, 593Zhang, Jane. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 287, 661Zhang, L.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 178Zhang, Lin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 775Zhang, Ling . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 219, 476, 478, 808, 854Zhang, Ping . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 47Zhang, Shuyuan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 274, 803Zhang, Song-Nan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 202, 811Zhang, Ting . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 493Zhang, Wei . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 574, 876Zhang, Wenli . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 92, 636Zhang, Xiaoling . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 756Zhang, Xiao-Xiang. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 392Zhang, Xichen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 515Zhang, Xiongwen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 217Zhang, Yadong . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 876Zhang, Yanling . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 219Zhang, Yonggong . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 251Zhang, Yonghui . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 694Zhang, Zheng-Yu. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 211Zhao, Hui Fen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 867Zhao, Huifen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 524, 525Zhao, Ling . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 789Zhao, Lu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 647Zhao, Tongmao . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 482Zhao-Chong, Zeng. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 73Zheng, Changyu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 77, 143, 761Zheng, Heng . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 580Zheng, Xin. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 808Zheng, Zhili . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 476, 478Zheng-Yu, Zhang. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 73Zhong, Li. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 58, 61, 363, 369, 370, 700Zhong-shan, Liu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 73Zhou, Dongming. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 389Zhou, Jiehua . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 287, 555Zhou, Jingmin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 69, 673Zhou, Liqin. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15Zhou, Shangzhen . . . . . . . . . . . . . . . . . . . . . . . . . . . . 43, 546, 615, 630, 885Zhou, Sheng . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 222, 860Zhou, Tian . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 108Zhou, Xiangyang . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 389Zhou, Xianzheng . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 868Zhou, Xiaoou . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 656Zhu, Liwei . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 186, 566EXHIBITOR PROSPECTUSfinal program

13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010 185Abstract Author IndexZhu, Quan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 645Zhu, Wen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 163Zhu, Zeng B. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 834Zhuge, Ying . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 603Zidovska, Alexandra . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 393Ziliotto, Raul . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 276Zimmermann, Katrin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 693Zinn, Kurt . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 36Zolopa, Andrew . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 646Zolotukhin, Irene . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 763Zolotukhin, Sergei. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 61, 371, 378Zoltick, Philip W.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 320, 344, 357, 676Zoon, Kathryn . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 482Zou, Jie. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 130Zou, Jizhong . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 220Zoumbos, Nikolas . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 340, 729Zourelias, Lee. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 104Zubair, Adnan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 689Zuhaili, Baraa. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 237Zurita, Juan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 185Zweier-Renn, Lynnsey A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 342, 690

186American Society of Gene & Cell TherapyNotesEXHIBITOR PROSPECTUSfinal program

ASGCT-1209-226Mark Your Calendars!American Socie t y of Gene & Cell Therapy14 th Annual MeetingS e at t l e , WA | May 18-22, 2 011Exciting scientific session topicswill include:- Stem Cell Therapeutics- Oligonucleotide Therapies- Novel Vector Development- Mechanisms of Vector Transduction- Host-Vector Interactions- Clinical Trial Advancements

FINAL PROGRAM - American Society of Gene & Cell Therapy

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