Mycobacterial Culture Test To Detect TB and Related Infections

Mycobacterial Culture Test To Detect TB and Related Infections

The Mycobacterial Culture Test is a laboratory procedure that helps doctors detect slow-growing bacteria responsible for diseases like tuberculosis, aiding in the diagnosis of respiratory infections.

 

Mycobacterial Culture Test

Here are the basic details of the Mycobacterial Culture Test.

Also Known As
  • TB Culture Test
  • Mycobacterial Culture Sensitivity Test
Type Microbiological Culture
Purpose Detects mycobacterial infections
Sample Type Sputum or other clinical samples
Preparation Sample decontamination
Fasting No
Gender Unisex
Age Group All
Normal Value Negative
Reporting Time within 24 hours
Cost 1000-1200 INR*

*Price range may vary as per location, lab type, and procedure of lab test.

 

Mycobacterial Culture Test Means

Mycobacterial Culture Test is a diagnostic procedure to identify slow-growing bacteria causing tuberculosis and other infections.

  • It uses sputum or clinical samples for observation, taking up to 8 weeks to report negative results.
  • Multiple tests may be needed for confirmation due to slow mycobacterial growth.
  • This test doesn't require fasting, suits all genders and age groups, and is crucial for accurate diagnosis.
  • Often, several tests may be required to confirm results, as mycobacteria grow slowly, impacting the test duration.



Mycobacterial Culture Test Purpose

The purpose of the Mycobacterial Culture Test is to:

  • Mycobacterial Culture Test identifies tuberculosis and other mycobacterial infections.
  • Enables tailored treatment plans for better patient outcomes.
  • Essential for preventing disease spread and public health management.
  • Offers definitive proof of mycobacterial infections for healthcare decisions.
  • Helps initiate appropriate therapies, enhancing recovery chances.

Mycobacterial Culture Test Price, Normal Range, Result, Purpose, Meaning and Interpretation - Drlogy Test Info

 

Mycobacterial Culture Test Preparation

Here is the basic preparation for the Mycobacterial Culture Test.

 

Before Test

  • Collect clinical sample (e.g., sputum) as per healthcare provider's instructions.
  • Label and transport the sample to the laboratory promptly.

 

During Test

  • Laboratory professionals perform sample decontamination if necessary.
  • Incubate the sample for a specified period to allow mycobacterial growth.

 

After Test

  • Observe for visible mycobacterial growth.
  • Report results to the healthcare provider for diagnosis and treatment planning.

 

Mycobacterial Culture Test Procedure

Here is the basic Mycobacterial Culture Test Procedure.

  • Obtain clinical sample (e.g., sputum) under aseptic conditions.
  • If needed, decontaminate the sample to remove unwanted microbes.
  • Place the prepared sample on special culture media.
  • Allow the culture to incubate for weeks, observing for growth.
  • Assess for mycobacterial growth and report findings.

 

Mycobacterial Culture Test Result

  • Positive Result: Indicates the presence of mycobacteria, potentially TB or another mycobacterial infection.
  • Negative Result: Suggests the absence of mycobacterial growth, reducing the likelihood of active TB or similar infections.
  • Confirmatory Testing: One positive result may require additional cultures for a definitive diagnosis.

 

Mycobacterial Culture Test Report

Mycobacterial Culture test report format example sample template- drlogy lab report

Mycobacterial Culture Test Report PDF

 

Mycobacterial Culture Test Positive Report

Mycobacterium Rapid Culture Positive Test Report Format Example Sample Template - Drlogy Pathology Lab Report Format

Mycobacterial Culture Positive Test Report PDF Format

Mycobacterial Culture Test Positive Result Report PDF

 

Mycobacterial Culture Test Negative Report

Mycobacterium Rapid Culture Negative Test Report Format Example Sample Template - Drlogy Pathology Lab Report Format

Mycobacterial Culture Negative Test Report PDF Format

Mycobacterial Culture Test Negative Result Report PDF

 

Mycobacterial Culture Test Normal Range

Here is the normal range of the Mycobacterial Culture Test.

Mycobacterial Culture Test Normal Range
Mycobacteria 10–100 cfu/ml

 

Mycobacterial Culture Test Interpretation

Here is the Interpretation of the Mycobacterial Culture Test.

Result Interpretation
Positive Indicates the presence of mycobacteria, potentially a mycobacterial infection, such as tuberculosis.
Negative Suggests the absence of mycobacterial growth, reducing the likelihood of active mycobacterial infections. Additional tests may be needed for confirmation.

Myco. Culture Test Positive means possible mycobacterial infection, while negative suggests no growth, but further tests may be needed.

 

Mycobacterial Culture Test Positive

Here are some possible causes of positive Mycobacterial Culture.

Possible Causes Effects
Tuberculosis (TB) Infection caused by Mycobacterium tuberculosis.
Nontuberculous Mycobacteria (NTM) Infections from various other mycobacterial species.
Other Respiratory Infections Conditions like lung abscess, pneumonia, or bronchitis.
Contaminants Potential for false positives due to contamination.

A positive Mycobacterial Culture Test result can indicate tuberculosis, nontuberculous mycobacteria, other respiratory infections, or potential contaminants.

 

Mycobacterial Culture Test Negative

Here are some possible causes of negative Mycobacterial Culture.

Possible Causes Effects
Absence of Mycobacterial Infection Indicates no growth of mycobacteria, reducing the likelihood of tuberculosis or other mycobacterial infections.
Early Infection Infections in very early stages may not yield positive results initially.
Sample Quality Poor quality samples can lead to false-negative results.
Non-Mycobacterial Infections Other pathogens may cause respiratory infections not detected by this test.

A negative Mycobacterial Culture Test result suggests the absence of mycobacterial infections, but early stages, poor sample quality, or non-mycobacterial causes can impact the outcome.

 

Specimen Requirements For Mycobacterial Culture Test

Here are the specimen requirements for the Mycobacterial Culture Test.

Specimen

Serum

Volume

1 ml

Container

Red-top tube or gel-barrier tube

Collection

Separate serum from cells within one hour of collection. Transfer to a plastic transport tube before shipping.

Storage

Refrigerate or freeze.

Sample Stability

Temperature

Period

Room temperature

7 day

Refrigerated

14 days

Frozen

60 days

Freeze/thaw cycles

Stable x1

Causes for Rejection

Grossly hemolyzed; bacterial contamination; lipemic specimen; icteric specimen; non-serum specimen types

 

Mycobacterial Culture Test is Safe?

Mycobacterial Culture Test is generally safe for patients undergoing the test.

  • Requires strict safety measures and a BSL-3 facility to prevent laboratory-acquired infections.
  • Potential risk of contamination if not handled properly.
  • Healthcare professionals follow safety protocols to minimize hazards.

 

When Do You Get Mycobacterial Culture Test Results? 

  • The exact duration depends on mycobacterial growth rate.
  • Positive results may be evident earlier, but confirmatory tests might take longer.
  • Negative results are reported after 6-8 weeks of incubation.

 

Mycobacterial Culture Test Limitation

Here is the basic limitation of Mycobacterial Culture Test.

  • Slow-growing mycobacteria.
  • Potential contamination risk.
  • Long incubation period.
  • Not suitable for rapid diagnosis.

 

Mycobacterial Culture Test Risk Factors

Here are some of the risk factors of the Mycobacterial Culture Test.

  • Laboratory staff exposed to mycobacteria.
  • Contaminated samples.
  • Inadequate biosafety precautions.
  • Mishandling or improper disposal.
  • Risk of airborne transmission if not handled in BSL-3 facilities.

 

Doctor Recommendations After Mycobacterial Culture Test Result

 Here are the Doctor's recommendations or consult a specialist after the Mycobacterial Culture Test.

Result Doctor to Visit Reason
Positive Infectious Disease Confirm and manage infection.
Negative Primary Care Further evaluation if symptoms persist.

 

Mycobacterial Culture Test Price

Here are the estimated Mycobacterial Culture Test Prices in India with different top cities:

City

Price Range (INR)*

Mumbai

1000-1200

New Delhi

1000-1200

Bangalore

1000-1200

Hyderabad

1000-1500

Kolkata

1000-1200

Pune

1000-1500

Lucknow

1000-1200

Noida

1000-1500

Surat

1000-1500

Gurugram

1000-1200

Patna

1000-1500

Chennai

1000-1200

Jaipur

1000-1500

Ahmedabad

1000-1200

*Prices are approximate and vary depending on a specific laboratory or healthcare facility.

 

Summary

Overall, The Mycobacterial Culture Test is a sensitive but time-consuming diagnostic tool, detecting mycobacterial infections like TB, aiding in accurate diagnosis. Also check Drlogy Test for detailed information about all medical tests for patients, doctors, scholars and medical students.

 

Reference

  • Mycobacterium - Wikipedia [1].
  • Mycobacterial culture Test - UCSF [2].

 

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Mycobacterial Culture Test FAQ

What is a Mycobacterial Culture Test?

The Mycobacterial Culture Test is a diagnostic procedure used to detect the presence of Mycobacteria in clinical specimens. Mycobacteria are responsible for diseases like tuberculosis and are slow-growing bacteria that require specialized culture techniques for isolation. This test helps in confirming the presence of these bacteria.

Why is a Mycobacterial Culture Test performed?

This test is done when there's suspicion of Mycobacterial infection, like TB, in a patient. It's crucial for diagnosis, treatment planning, and monitoring. Culturing allows for drug susceptibility testing, aiding in choosing the most effective antibiotics.

What is the procedure for a Mycobacterial Culture Test?

The collected specimen is placed in a culture medium designed to support Mycobacterial growth. It's then incubated for several weeks, and the growth is monitored regularly. Identification is done through staining and microscopy.

Can Mycobacterial Culture Test be done at home?

No, this test requires specialized laboratory equipment and expertise, so it can't be done at home. It should be conducted by trained healthcare professionals in a clinical setting to ensure accuracy and safety.

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