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Chronic Ulceration from Mycobacterium marinum Infection and the Diagnostic Value of T-Cell Interferon-γ Release Assays

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Abstract

This case report describes the differential diagnosis of cutaneous ulcerations and the utility of the interferon-γ release assays as a tool to aid in the diagnosis. These new assays can be used to identify mycobacterial infections (specifically Mycobacterium marinum) as the etiologic agents.

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References

  1. Griffith DE, Wallace Jr R J. Myocobacterium marinum. In: Yu VL, Merigan TC, Barriere SL. Antimicrobial therapy and vaccines. Vol. I: microbes [online]. Available from URL: http://www.antimicrobe.org [Accessed 2010 Jan 18]

  2. Beran V, Matlova L, Dworska L, et al. Distribution of mycobacteria in clinically healthy ornamental fish and their aquarium environment. J Fish Dis 2006 Jul; 29(7): 383–93

    Article  PubMed  CAS  Google Scholar 

  3. Bartralot R, Garcia-Patos V, Sitjas D, et al. Clinical patterns of cutaneous nontuberculous mycobacterial infections. Br J Dermatol 2005 Apr; 152(4): 727–34

    Article  PubMed  CAS  Google Scholar 

  4. Speight L, William H. Fish tank granuloma in a 14-month old girl. Ped Derm 1997; 14(3): 209–12

    Article  CAS  Google Scholar 

  5. Brown BA, Wallace RJ. Infections caused by nontuberculous mycobacteria. In: Mandell GL, Bennett JE, Dolin R. Mandell principles and practice of infectious diseases. 6th ed. Vol. 2. Philadelphia: Elsevier, Churchill-Livingstone, 2005: 2909–16

    Google Scholar 

  6. Lalvani A. Diagnosing tuberculosis infection in the 21st century: new tools to tackle an old enemy. Chest 2007 Jun; 131(6): 1898–906

    Article  PubMed  Google Scholar 

  7. Kobashi Y, Mouri K, Yagi S, et al. Clinical evaluation of the QuantiFERON®-TB Gold test in patients with non-tuberculous mycobacterial disease. Int J Tuberc Lung Dis 2009; 13(11): 1422–6

    PubMed  CAS  Google Scholar 

  8. Mazureck GH, Jereb J, Lobue P, et al. Guidelines for using the QuantiFERON®-TB Gold test for detecting Myocobacterium tuberculosis infection, United States [published erratum appears in MMWR Morb Mortal Wkly Rep 2005; 54 (50): 1288]. MMWR Recomm Rep 2005; 54(RR-15): 49–55

    Google Scholar 

  9. Iseman MD, Atwood Jr CW. Group II: scotochromogenic Mycobacterium (M. scrofulaceum, M. szulgai, M. gordonae). In: Yu VL, Merigan TC, Barriere SL. Antimicrobial therapy and vaccines. Vol. I: microbes [online]. Available from URL: http://www.antimicrobe.org [Accessed 2010 Jan 18]

  10. Ena P, Sechi LA, Saccabusi S, et al. Rapid identification of cutaneous infections by nontubercular mycobacteria by polymerase chain reaction-restriction analysis length polymorphism of the hsp65 gene. Int J Dermatol 2001 Aug; 40(8): 495–9

    Article  PubMed  CAS  Google Scholar 

  11. Noguchi M, Taniwaki Y, Tani T. Atypycal mycobacterial infections of the upper extremity. Arch Orthop Trauma Surg 2005; 125: 475–8

    Article  PubMed  Google Scholar 

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Acknowledgments

No sources of funding were used to assist in the preparation of this article. The authors have no conflicts of interest that are directly relevant to the content of this article.

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Authors and Affiliations

  1. Department of Medicine, Hospital Universitario de La Ribera, Carretera de Corbera Km 1, Alzira, 46600, Spain

    Emilio V. Perez-Jorge

  2. Department of Medicine, Wright State University Boonshoft School of Medicine, Dayton, Ohio, USA

    Steven D. Burdette

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  1. Emilio V. Perez-Jorge
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  2. Steven D. Burdette
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Correspondence to Emilio V. Perez-Jorge.

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Perez-Jorge, E.V., Burdette, S.D. Chronic Ulceration from Mycobacterium marinum Infection and the Diagnostic Value of T-Cell Interferon-γ Release Assays. Mol Diag Ther 14, 119–122 (2010). https://doi.org/10.1007/BF03256362

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