- Primary neurotransmitter of CNS output
- Moves muscles
- Autonomic nervous system
- Role in REM sleep and learning
- Acetylcholinesterase (AChE) degradation:
AcH Receptors Khan Academy: Types of Neurotransmitter Receptors
- Cholinergic: Neurons releasing AcH
- Ionotropic (nicotinic)
- Moves skeletal muscles
- Mostly excitatory
- Blocked by curare
- Metabotropic (muscarinic)
- In brain M> N
- Slower, but excitatory and inhibitory
- Blocked by atropine (ex: iris dilator muscle of eye)
McGraw Hill: Animation: Function of the Neuromuscular Junction (Quiz 3)
Khan Academy: Neuronal Synapses (Chemical)