Acetylcholine (ACh)

  • Primary neurotransmitter of CNS output
  • Moves muscles
  • Autonomic nervous system
  • Role in REM sleep and learning
  • Acetylcholinesterase (AChE) degradation:
  •  AChE Degradation and Recycle

AcH Receptors Khan Academy: Types of Neurotransmitter Receptors

  • Cholinergic: Neurons releasing AcH
  • Ionotropic (nicotinic)
  • Moves skeletal muscles
  • Mostly excitatory
  • Blocked by curare
  • Metabotropic (muscarinic)
  • In brain M> N
  • Slower, but excitatory and inhibitory
  • Blocked by atropine (ex: iris dilator muscle of eye)

McGraw Hill: Animation: Function of the Neuromuscular Junction (Quiz 3)

Khan Academy: Neuronal Synapses (Chemical)

 

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