Causes of Portal Hypertension According to Site of Vascular Obstruction

1) Prehepatic pre-sinusoidal: Portal vein thrombosis due to sepsis (umbilical, portal pyaemia) or procoagulopathy or secondary to cirrhosis, Abdominal trauma including surgery

2) Intrahepatic pre-sinusoidal: Schistosomiasis, Congenital hepatic fibrosis, Drugs, Vinyl chloride, Sarcoidosis

3) Sinusoidal: Cirrhosis, Polycystic liver disease, Nodular regenerative hyperplasia, Metastatic malignant disease

4) Intrahepatic post-sinusoidal: Veno-occlusive disease

5) Post-hepatic post-sinusoidal: Budd-Chiari syndrome



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