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2-Butanol (CAS 78-92-2)

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Alternate Names:
sec-Butyl alcohol
Application:
2-Butanol is a useful alcohol for proteomics research
CAS Number:
78-92-2
Purity:
≥99%
Molecular Weight:
74.12
Molecular Formula:
C4H10O
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

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2-Butanol, also referred to as sec-butanol or 2-methyl-1-propanol, falls under the category of short-chain alcohols in organic compounds. This transparent and colorless liquid possesses water solubility and emits a distinct scent. Its flammability and toxicity make it a substance of caution, finding widespread use in various industrial and commercial sectors. In scientific investigations, 2-Butanol serves as a solvent, enabling the dissolution of diverse substances for separation and analysis purposes. It acts as a surfactant, effectively reducing the surface tension of aqueous solutions and facilitating their mixing. In the realm of scientific research and various industries, 2-Butanol demonstrates its versatility and utility through its properties and diverse applications.

References:

  1. The participation of 2-butanone in 2-butanol-induced potentiation of carbon tetrachloride hepatotoxicity.  |  Traiger, GJ. and Bruckner, JV. 1976. J Pharmacol Exp Ther. 196: 493-500. PMID: 1255493
  2. 1-Butanol targets the Golgi apparatus in tobacco BY-2 cells, but in a different way to Brefeldin A.  |  Langhans, M. and Robinson, DG. 2007. J Exp Bot. 58: 3439-47. PMID: 17977851
  3. Shock tube studies on the decomposition of 2-butanol.  |  Rosado-Reyes, CM. and Tsang, W. 2012. J Phys Chem A. 116: 9599-606. PMID: 22946999
  4. Production of 2-butanol from crude glycerol by a genetically-engineered Klebsiella pneumoniae strain.  |  Oh, BR., et al. 2014. Biotechnol Lett. 36: 57-62. PMID: 24078128
  5. 2-Butanol and butanone production in Saccharomyces cerevisiae through combination of a B12 dependent dehydratase and a secondary alcohol dehydrogenase using a TEV-based expression system.  |  Ghiaci, P., et al. 2014. PLoS One. 9: e102774. PMID: 25054226
  6. Effect of 2-butanol and 2-butanone on rat hepatic ultrastructure and drug metabolizing enzyme activity.  |  Traiger, GJ., et al. 1989. J Toxicol Environ Health. 28: 235-48. PMID: 2507790
  7. Production of 2-butanol through meso-2,3-butanediol consumption in lactic acid bacteria.  |  Ghiaci, P., et al. 2014. FEMS Microbiol Lett. 360: 70-5. PMID: 25175699
  8. Metabolic engineering of Klebsiella pneumoniae for the de novo production of 2-butanol as a potential biofuel.  |  Chen, Z., et al. 2015. Bioresour Technol. 197: 260-5. PMID: 26342337
  9. Integrated Vacuum Stripping and Adsorption for the Efficient Recovery of (Biobased) 2-Butanol.  |  Pereira, JPC., et al. 2019. Ind Eng Chem Res. 58: 296-305. PMID: 30774191
  10. Microbial 2-butanol production with Lactobacillus diolivorans.  |  Russmayer, H., et al. 2019. Biotechnol Biofuels. 12: 262. PMID: 31709011
  11. Synergy at work: linking the metabolism of two lactic acid bacteria to achieve superior production of 2-butanol.  |  Mar, MJ., et al. 2020. Biotechnol Biofuels. 13: 45. PMID: 32180827
  12. P-x,y Equilibrium Data of the Binary Systems of 2-Propanol, 1-Butanol and 2-Butanol with Carbon Dioxide at 313.15 K and 333.15 K.  |  Borjan, D., et al. 2022. Molecules. 27: PMID: 36500443
  13. Pharmacokinetics of 2-butanol and its metabolites in the rat.  |  Dietz, FK., et al. 1981. J Pharmacokinet Biopharm. 9: 553-76. PMID: 7334459