2. Ectopic pregnancy is a high-risk condition where in a
fertilized ovum gets implanted outside the uterine
cavity.
This condition poses a significant threat to women
of reproductive age and is a leading cause of
maternaldeathduringthe first trimester.
Introduction
3. Ectopic pregnancy still contributes significantly to the
cause of maternalmortalityand morbidity.
While there has been about fourfold increase in
incidence over the couple of decades, but the
mortalityhasbeenslasheddownby 80%.
Recognition of high-risk cases , early diagnosis (even
before rupture) with the use of TVS, serum Beta-
hCG and laparoscopy have significantly improved the
managementof ectopicpregnancy.
Incidence
9. Classicaltriad found in only 1/3rd cases
Pain 90 % cases
Amenorrhoea 80 % cases
Bleeding 70 % cases
Symptomsof shockin acute rupture
Faintingattack typical but rare
It can be asymptomaticalso
Clinical Presentation (Symptoms)
Ectopic pregnancy is a great deceiver
11. Different Presentations
Emergency presentation Suddenly, without
warning a woman is very unwell, collapses and is
taken to hospital in stage of haemoperitoneum
and hemorrhagic shock.
Subacute presentation The most common
presentation is with a missed period, positive
pregnancy test, some abdominal pain, and
irregular vaginal bleeding
High Risk Pregnancy Group After previous
ectopic, tubal surgery or assisted conception
(IVF) → detection rate is high → women are
primary observed.
12. The discriminatory zone is based upon the
correlation between visibility of the gestational sac
andthehCGconcentration.
It is defined as the serum hCG level above which a
gestational sac should be visualized by ultrasound
examinationif an intrauterinepregnancyis present.
In most institutions, this serum hCG level is 1500 or
2000 IU/LwithTVS “
Thelevelishigher[6500 IU/L]withTAS.
Discriminatory Zone
13. Serum hCG greater than 1500 IU/L without
visualization of intrauterine or extrauterine
pathology may represent a multiple gestation
repeat the TVS examination and hCG concentration
two dayslater.
An ectopic pregnancy can be diagnosed if the serum
hCG concentration is increasing or plateaued.
Treatment can be instituted.
A falling hCG concentration is most consistent with a
failed pregnancy (eg, arrested pregnancy, blighted
ovum, tubal abortion, spontaneously resolving
ectopicpregnancy).
B-HCG Above The Discriminatory Zone